In this work, we experimentally demonstrate an image information transfer between two channels by using slow light based on electromagnetically induced transparency（EIT） in a solid. The probe optical image is slowed...In this work, we experimentally demonstrate an image information transfer between two channels by using slow light based on electromagnetically induced transparency（EIT） in a solid. The probe optical image is slowed due to steep dispersion induced by EIT. By applying an additional control field to an EIT-driven medium, the slowed image is transferred into two information channels. Image intensities between two information channels can be controlled by adjusting the intensities of the control fields. The similarity of output images is further analyzed. This image information transfer allows for manipulating images in a controlled fashion, and will be important in further information processing.展开更多
We focus on the study of the transferred image property in an electromagnetically induced transparency （EIT）system. In our experiment, a triple-peak image is effectively transferred trom a coupling beam to a signal ...We focus on the study of the transferred image property in an electromagnetically induced transparency （EIT）system. In our experiment, a triple-peak image is effectively transferred trom a coupling beam to a signal beam based on the FIT effect. It is found that the transferred image intensity profile of the signal beam is the same as that of the coupling beam while not in phase. Furthermore, the propagation property of the transferred image is studied. Due to the narrowing effect, the transferred image keeps narrowing and maintains the shape well within a certain distance outside of the medium. Our experimental results are in excellent agreement with the theoretical analysis.展开更多
Fast Fourier Transfer Image Processing was widely applied to the analysis of wood anatomy structure in re-cent years. The cells in the wood transverse section have obviously periodicity and regularity. FFT power spect...Fast Fourier Transfer Image Processing was widely applied to the analysis of wood anatomy structure in re-cent years. The cells in the wood transverse section have obviously periodicity and regularity. FFT power spectral patternscan extract the periodic characteristics so that they can be compared. identified and classified quaytitatively. This paperSummarizes the application of FFT image analysis in wood science and the general way to study wood anatomy by FFT.展开更多
Amide proton transfer (APT) magnetic resonance imaging (MRI) is an important molecularimaging technique at the protein level in tissue. Neurodegenerative diseases have a highlikelihood of causing abnormal protein accu...Amide proton transfer (APT) magnetic resonance imaging (MRI) is an important molecularimaging technique at the protein level in tissue. Neurodegenerative diseases have a highlikelihood of causing abnormal protein accumulation in the brain, which can be detectedby APT MRI. This article briefly introduces the principles and image processing technologyof APT MRI, and reviews the current state of research on Alzheimer's disease and Parkinson's disease using this technique. Early applications of this approach in these twoneurodegenerative diseases are encouraging, which also suggests continued technicaldevelopment and larger clinical trials to gauge the value of this technique.展开更多
A novel low-cost sub-50nm poly-Si gate patterning technology is proposed and experimentally demonstrated.The technology is resolution-independent,ie.,it does not contain any critical photolithographic steps.The nano-s...A novel low-cost sub-50nm poly-Si gate patterning technology is proposed and experimentally demonstrated.The technology is resolution-independent,ie.,it does not contain any critical photolithographic steps.The nano-scale masking pattern for gate formation is formed according to the image transfer of an edge-defined spacer.Experimental results reveal that the resultant gate length,about 75 to 85 percent of the thickness,is determined by the thickness of the film to form the spacer.From SEM photograph,the cross-section of the poly-Si gate is seen to be an inverted-trapezoid,which is useful to reduce the gate resistance.展开更多
AIM: To evaluate the spatial distribution of cerebral abnormalities in cirrhotic subjects with and without hepatic encephalopathy (HE) found with magnetization transfer imaging (MTI).METHODS: Nineteen cirrhotic patien...AIM: To evaluate the spatial distribution of cerebral abnormalities in cirrhotic subjects with and without hepatic encephalopathy (HE) found with magnetization transfer imaging (MTI).METHODS: Nineteen cirrhotic patients graded from neurologically normal to HE grade 2 and 18 healthy control subjects underwent magnetic resonance imaging. They gave institutional-review-board-approved written consent. Magnetization transfer ratio (MTR) maps were generated from MTI. We tested for significant differences compared to the control group using statistical non-parametric mapping (SnPM) for a voxelbased evaluation.RESULTS: The MTR of grey and white matter was lower in subjects with more severe HE. Changes were found in patients with cirrhosis without neurological defi cits in the basal ganglia and bilateral white matter. The loss in magnetization transfer increased in severity and spatial extent in patients with overt HE. Patients with HE grade 2 showed an MTR decrease in white and grey matter: the maximum loss of magnetization transfer effect was located in the basal ganglia [SnPM (pseudo-)t = 17.98, P = 0.0001].CONCLUSION: The distribution of MTR changes in HE points to an early involvement of basal ganglia and white matter in HE.展开更多
Background:Patients with schizophrenia(SCZ)and major depressive disorder(MDD)share significant clinical overlap,although it remains unknown to what extent this overlap reflects shared neural profiles.To identify the s...Background:Patients with schizophrenia(SCZ)and major depressive disorder(MDD)share significant clinical overlap,although it remains unknown to what extent this overlap reflects shared neural profiles.To identify the shared and specific abnormalities in SCZ and MDD,we performed a whole-brain voxel-based meta-analysis using magnetization transfer imaging,a technique that characterizes the macromolecular structural integrity of brain tissue in terms of the magnetization transfer ratio(MTR).Methods:A systematic search based on Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines was conducted in PubMed,EMBASE,International Scientific Index(ISI)Web of Science,and MEDLINE for relevant studies up to March 2022.Two researchers independently screened the articles.Rigorous scrutiny and data extraction were performed for the studies that met the inclusion criteria.Voxel-wise meta-analyses were conducted using anisotropic effect size-signed differential mapping with a unified template.Meta-regression was used to explore the potential effects of demographic and clinical characteristics.Results:A total of 15 studies with 17 datasets describing 365 SCZ patients,224 MDD patients,and 550 healthy controls(HCs)were identified.The conjunction analysis showed that both disorders shared higher MTR than HC in the left cerebellum(P=0.0006)and left fusiform gyrus(P=0.0004).Additionally,SCZ patients showed disorder-specific lower MTR in the anterior cingulate/paracingulate gyrus,right superior temporal gyrus,and right superior frontal gyrus,and higher MTR in the left thalamus,precuneus/cuneus,posterior cingulate gyrus,and paracentral lobule;and MDD patients showed higher MTR in the left middle occipital region.Meta-regression showed no statistical significance in either group.Conclusions:The results revealed a structural neural basis shared between SCZ and MDD patients,emphasizing the importance of shared neural substrates across psychopathology.Meanwhile,distinct disease-specific characteristics could have implications for future differential diagnosis and targeted treatment.展开更多
Background：Amide proton transfer （APT） imaging has recently emerged as an important contrast mechanism for magnetic resonance imaging （MRI） in the field of molecular and cellular imaging.The aim of this study was...Background：Amide proton transfer （APT） imaging has recently emerged as an important contrast mechanism for magnetic resonance imaging （MRI） in the field of molecular and cellular imaging.The aim of this study was to evaluate the feasibility of APT imaging to detect cerebral abnormality in patients with Alzheimer＆#39;s disease （AD） at 3.0 Tesla.Methods：Twenty AD patients （9 men and 11 women; age range,67-83 years） and 20 age-matched normal controls （11 men and 9 women; age range,63-82 years） underwent APT and traditional MRI examination on a 3.0 Tesla MRI system.The magnetic resonance ratio asymmetry （MTRasym） values at 3.5 ppm of bilateral hippocampi （Hc）,temporal white matter regions,occipital white matter regions,and cerebral peduncles were measured on oblique axial APT images.MTRasym （3.5 ppm） values of the cerebral structures between AD patients and control subjects were compared with independent samples t-test.Controlling for age,partial correlation analysis was used to investigate the associations between mini-mental state examination （MMSE） and the various MRI measures among AD patients.Results：Compared with normal controls,MTRasym （3.5 ppm） values of bilateral Hc were significantly increased in AD patients （right 1.24% ± 0.21% vs.0.83% ± 0.19%,left 1.18% ± 0.18% vs.0.80%± 0.17%,t =3.039,3.328,P =0.004,0.002,respectively）.MTRasym （3.5 ppm） values of bilateral Hc were significantly negatively correlated with MMSE （right r =-0.559,P =0.013; left r=-0.461,P =0.047）.Conclusions：Increased MTRasym （3.5 ppm） values of bilateral Hc in AD patients and its strong correlations with MMSE suggest that APT imaging could potentially provide imaging biomarkers for the noninvasive molecular diagnosis of AD.展开更多
基金Project supported by the National Basic Research Program of China(Grant No.2011CB921603)the National Natural Science Foundation of China(Grant Nos.11374126,11347137,11204103,11404336,and 11204029)the Fund for Fostering Talents in Basic Science of the National Natural Science Foundation of China(Grant No.J1103202)
文摘In this work, we experimentally demonstrate an image information transfer between two channels by using slow light based on electromagnetically induced transparency（EIT） in a solid. The probe optical image is slowed due to steep dispersion induced by EIT. By applying an additional control field to an EIT-driven medium, the slowed image is transferred into two information channels. Image intensities between two information channels can be controlled by adjusting the intensities of the control fields. The similarity of output images is further analyzed. This image information transfer allows for manipulating images in a controlled fashion, and will be important in further information processing.
基金Supported by the National Natural Science Foundation of China under Grant Nos 11374238,11374239,11534008,11574247 and 11374008the China Postdoctoral Science Foundation under Grant No 2016M592771
文摘We focus on the study of the transferred image property in an electromagnetically induced transparency （EIT）system. In our experiment, a triple-peak image is effectively transferred trom a coupling beam to a signal beam based on the FIT effect. It is found that the transferred image intensity profile of the signal beam is the same as that of the coupling beam while not in phase. Furthermore, the propagation property of the transferred image is studied. Due to the narrowing effect, the transferred image keeps narrowing and maintains the shape well within a certain distance outside of the medium. Our experimental results are in excellent agreement with the theoretical analysis.
文摘Fast Fourier Transfer Image Processing was widely applied to the analysis of wood anatomy structure in re-cent years. The cells in the wood transverse section have obviously periodicity and regularity. FFT power spectral patternscan extract the periodic characteristics so that they can be compared. identified and classified quaytitatively. This paperSummarizes the application of FFT image analysis in wood science and the general way to study wood anatomy by FFT.
文摘Amide proton transfer (APT) magnetic resonance imaging (MRI) is an important molecularimaging technique at the protein level in tissue. Neurodegenerative diseases have a highlikelihood of causing abnormal protein accumulation in the brain, which can be detectedby APT MRI. This article briefly introduces the principles and image processing technologyof APT MRI, and reviews the current state of research on Alzheimer's disease and Parkinson's disease using this technique. Early applications of this approach in these twoneurodegenerative diseases are encouraging, which also suggests continued technicaldevelopment and larger clinical trials to gauge the value of this technique.
文摘A novel low-cost sub-50nm poly-Si gate patterning technology is proposed and experimentally demonstrated.The technology is resolution-independent,ie.,it does not contain any critical photolithographic steps.The nano-scale masking pattern for gate formation is formed according to the image transfer of an edge-defined spacer.Experimental results reveal that the resultant gate length,about 75 to 85 percent of the thickness,is determined by the thickness of the film to form the spacer.From SEM photograph,the cross-section of the poly-Si gate is seen to be an inverted-trapezoid,which is useful to reduce the gate resistance.
文摘AIM: To evaluate the spatial distribution of cerebral abnormalities in cirrhotic subjects with and without hepatic encephalopathy (HE) found with magnetization transfer imaging (MTI).METHODS: Nineteen cirrhotic patients graded from neurologically normal to HE grade 2 and 18 healthy control subjects underwent magnetic resonance imaging. They gave institutional-review-board-approved written consent. Magnetization transfer ratio (MTR) maps were generated from MTI. We tested for significant differences compared to the control group using statistical non-parametric mapping (SnPM) for a voxelbased evaluation.RESULTS: The MTR of grey and white matter was lower in subjects with more severe HE. Changes were found in patients with cirrhosis without neurological defi cits in the basal ganglia and bilateral white matter. The loss in magnetization transfer increased in severity and spatial extent in patients with overt HE. Patients with HE grade 2 showed an MTR decrease in white and grey matter: the maximum loss of magnetization transfer effect was located in the basal ganglia [SnPM (pseudo-)t = 17.98, P = 0.0001].CONCLUSION: The distribution of MTR changes in HE points to an early involvement of basal ganglia and white matter in HE.
基金National Key R&D Program of China(No.2022YFC2009904/2022YFC2009900)National Natural Science Foundation(Nos.81621003,81820108018,82027808,and 82001800)Young Elite Scientists Sponsorship Program by CAST(No.2022QNRC001)
文摘Background:Patients with schizophrenia(SCZ)and major depressive disorder(MDD)share significant clinical overlap,although it remains unknown to what extent this overlap reflects shared neural profiles.To identify the shared and specific abnormalities in SCZ and MDD,we performed a whole-brain voxel-based meta-analysis using magnetization transfer imaging,a technique that characterizes the macromolecular structural integrity of brain tissue in terms of the magnetization transfer ratio(MTR).Methods:A systematic search based on Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines was conducted in PubMed,EMBASE,International Scientific Index(ISI)Web of Science,and MEDLINE for relevant studies up to March 2022.Two researchers independently screened the articles.Rigorous scrutiny and data extraction were performed for the studies that met the inclusion criteria.Voxel-wise meta-analyses were conducted using anisotropic effect size-signed differential mapping with a unified template.Meta-regression was used to explore the potential effects of demographic and clinical characteristics.Results:A total of 15 studies with 17 datasets describing 365 SCZ patients,224 MDD patients,and 550 healthy controls(HCs)were identified.The conjunction analysis showed that both disorders shared higher MTR than HC in the left cerebellum(P=0.0006)and left fusiform gyrus(P=0.0004).Additionally,SCZ patients showed disorder-specific lower MTR in the anterior cingulate/paracingulate gyrus,right superior temporal gyrus,and right superior frontal gyrus,and higher MTR in the left thalamus,precuneus/cuneus,posterior cingulate gyrus,and paracentral lobule;and MDD patients showed higher MTR in the left middle occipital region.Meta-regression showed no statistical significance in either group.Conclusions:The results revealed a structural neural basis shared between SCZ and MDD patients,emphasizing the importance of shared neural substrates across psychopathology.Meanwhile,distinct disease-specific characteristics could have implications for future differential diagnosis and targeted treatment.
文摘Background：Amide proton transfer （APT） imaging has recently emerged as an important contrast mechanism for magnetic resonance imaging （MRI） in the field of molecular and cellular imaging.The aim of this study was to evaluate the feasibility of APT imaging to detect cerebral abnormality in patients with Alzheimer＆#39;s disease （AD） at 3.0 Tesla.Methods：Twenty AD patients （9 men and 11 women; age range,67-83 years） and 20 age-matched normal controls （11 men and 9 women; age range,63-82 years） underwent APT and traditional MRI examination on a 3.0 Tesla MRI system.The magnetic resonance ratio asymmetry （MTRasym） values at 3.5 ppm of bilateral hippocampi （Hc）,temporal white matter regions,occipital white matter regions,and cerebral peduncles were measured on oblique axial APT images.MTRasym （3.5 ppm） values of the cerebral structures between AD patients and control subjects were compared with independent samples t-test.Controlling for age,partial correlation analysis was used to investigate the associations between mini-mental state examination （MMSE） and the various MRI measures among AD patients.Results：Compared with normal controls,MTRasym （3.5 ppm） values of bilateral Hc were significantly increased in AD patients （right 1.24% ± 0.21% vs.0.83% ± 0.19%,left 1.18% ± 0.18% vs.0.80%± 0.17%,t =3.039,3.328,P =0.004,0.002,respectively）.MTRasym （3.5 ppm） values of bilateral Hc were significantly negatively correlated with MMSE （right r =-0.559,P =0.013; left r=-0.461,P =0.047）.Conclusions：Increased MTRasym （3.5 ppm） values of bilateral Hc in AD patients and its strong correlations with MMSE suggest that APT imaging could potentially provide imaging biomarkers for the noninvasive molecular diagnosis of AD.
