BACKGROUND: Previous studies reported that frontal-temporal-parietal-occipital pathological changes and diseased range in the right cerbral hemisphere were correlated with neglect.But studies on the correlation of neg...BACKGROUND: Previous studies reported that frontal-temporal-parietal-occipital pathological changes and diseased range in the right cerbral hemisphere were correlated with neglect.But studies on the correlation of neglect with diseased region and area in patients who suffer from initial attack of single focus of cerebral infarction(CI) in left and right cerebral hemispheres are few.OBJECTIVE: To observe the status of neglect in patients who suffer from single focus of CI in cerebral hemisphere and analyze the correlation of neglect with diseased region and area of CI.DESIGN: Case analysis SETTING: Treatment Center for Cardiocerebrovascular Disease,Second Hospital of Xiamen city;Department of Neurology,First Hospital Affiliated to Baotou Medical College.PARTICIPANTS: All the CI patients hospitalized in the Department of Neurology.First Hospital Affiliated to Baotou Medical College from June 1998 to May 2001 were retrieved.Inclusive criteria:①Patients who suffered from initial attack of CI.which was confirmed by skull CT or MRI within 24 hours after onset and presented single focus in cerebral hemisphere. ②be conscious and could cooperate in the examination. ③did not receive formal education, but could do accounts and some simple writing and reading. ④Patients with homonymous hemianopia were excluded through the examination of perimeter.⑤Informed consents were obtained from all the patients.Among 67 patients who met the inclusive criteria.33 suffered from CI in the left cerebral hemisphere and 34 in the right cerebral hemisphere.METHODS:①Patients received neglect supplement examination and Chinese aphasia examination within 2.5 to 3 months after the attack of CI.The diagnostic criteria of neglect in the tests of line cancellation. 1ine bisection and copying the figures were as follows:In the line cancellation test based on the method of Albert.patients who could not cancel one or more lines were regarded as abnormal.In the line bisection test based on the method of Peter.patients who left deviated 1.16% or right deviated 2.51% were regarded as abnormal.In the test of copying the figures,round-shape,square,cruciform and other shapes were asked to be copied, defect appeared in the figure was regarded as abnormal.The diagnostic criteria of aphasia were according to the diagnostic method of Chinese aphasia examination and type identification flow-sheet of aphasia. Infarct area was calculated based on Palisino formula: infarct area=π/6×the longest diameter of infarct area×the widest diameter of infarct area×the number of CT positive layer.②Chi-square test was used for compadng the difference of measurement data.MAIN OUTCOME MEASURES:Diseased region and area of CI and their correlations with neglect.RESULTS:Sixty-seven patients were involved in result analysis.①The correlation of the occurrence of neglect with the diseased regions of CI:Neglect was not found in 33 patients with CI in left cerebral hemisphere.but was found in 7 of 34 patients with CI in right cerebral hemisphere.The diseased regions involved right temporoparietal region,temporal-parietal-occipital region,frontal-temporal-parietal region,frontal-temporal-parietal-occipital region,temporoparietal basal nucleus,basal nucleus and dorsal caudate putamen.②The correlation of the occurrence of neglect with diseased area:infarcl area≤30 cm3 was found in 2 patients with neglect(12.5%).infarct area at 31 to 60 cm3 in 1 patient with neglect(14.3%),infarct area≥61 cm3 in 4 patients with neglect (36.4%).There was no significant difference in infarct area among groups(P＞0.05).CONCLUSION:①Right cerebral hemisphere takes advantage in spatial attention.②Neglect is more possibly caused by the combined pathological changes in temporal and parietal lobe.Temporal and parietal lobes may not cause neglect independently,but the occurrence of neglect is not directly correlated with infarct area.展开更多
Objective:To investigate the clinical effects of applying the magnetic resonance double mismatch technique to endovascular treatment of acute anterior circulation,large vessel occlusion with cerebral infarction in an ...Objective:To investigate the clinical effects of applying the magnetic resonance double mismatch technique to endovascular treatment of acute anterior circulation,large vessel occlusion with cerebral infarction in an unknown time window.Methods:The research work was carried out in our hospital,the work was carried out from November 2018 to November 2019,the patients with acute anterior circulation large vessel occlusion with cerebral infarction who were treated in our hospital during this period,100 patients,50 patients with an unknown time window and 50 patients with definite time window were selected,and they were named as the experimental and control groups,given different examination methods,were given to investigate the clinical treatment effect.Results:Patients’data on HIHSS score before treatment,the incidence of intracranial hemorrhage and rate of Mrs≤2 rating after 90 days of treatment were not significantly different(P>0.05),which was not meaningful.The differences in data between the two groups concerning HIHSS scores were relatively significant before,and after treatment(P<0.05).Conclusion:The magnetic resonance double mismatch technique will be applied in the endovascular treatment of acute anterior circulation large vessel occlusion with cerebral infarction of unknown time window.展开更多
We reported a 50-year-old female patient with left supplementary motor area infarction who presented right lower limb apraxia and investigated the possible causes using transcranial magnetic stimulation. The patient w...We reported a 50-year-old female patient with left supplementary motor area infarction who presented right lower limb apraxia and investigated the possible causes using transcranial magnetic stimulation. The patient was able to walk and climb stairs spontaneously without any assistance at 3 weeks after onset. However, she was unable to intentionally move her right lower limb although she understood what she supposed to do. The motor evoked potential evoked by transcranial magnetic stimulation from the right lower limb was within the normal range, indicating that the corticospinal tract innervating the right lower limb was uninjured. Thus, we thought that her motor dysfunction was not induced by motor weakness, and confirmed her symptoms as apraxia. In addition, these results also suggest that transcranial magnetic stimulation is helpful for diagnosing apraxia.展开更多
Objective:Study the clinical effect of atorvastatin combined with clopidogrel on patients with progressive cerebral infarction of intracranial aortic stenosis.Methods: Chose eighty-eight patients with progressive cere...Objective:Study the clinical effect of atorvastatin combined with clopidogrel on patients with progressive cerebral infarction of intracranial aortic stenosis.Methods: Chose eighty-eight patients with progressive cerebral infarction in our hospital from June 2014 to October 2015. They were randomly divided into study group and study group, 44 cases in each group. The patients in the control group were treated with oral clopidogrel. On the basis of this, the patients in the study group were treated with atorvastatin;all patients were treated for 4 weeks. Compared the total effective rate, adverse reaction rate, coagulation function index and blood lipid level between the two groups, and compared the NIHSS score and daily life ability (ADL) score between the two groups before and after treatment.Results: The total effective rate (90.90%) was significantly higher in the study group than in the control group (72.73%). After treatment, the NIHSS score of the study group was significantly lower than that of the control group. The levels of LDL-C, TG and TC in the study group were significantly lower than those in the control group, and HDL-C was significantly higher than that in the control group. There was no significant difference between the two groups.Conclusion: Clopidogrel combined with atorvastatin has a significant effect on the patients with intracranial large artery stenosis and improve the neurological function and quality of life. It is safe and reliable. It is worthy to be popularized.展开更多
目的探究急性大面积脑梗死患者开展开颅去大骨瓣减压联合康复治疗的临床效果。方法选择2021年2月—2023年2月高密市人民医院收治的46例急性大面积脑梗死患者为研究对象,按随机数表法分为研究组和对照组,各23例。所有患者全部开展开颅去...目的探究急性大面积脑梗死患者开展开颅去大骨瓣减压联合康复治疗的临床效果。方法选择2021年2月—2023年2月高密市人民医院收治的46例急性大面积脑梗死患者为研究对象,按随机数表法分为研究组和对照组,各23例。所有患者全部开展开颅去大骨瓣减压术治疗,对照组予以基础康复治疗,研究组予以综合康复治疗。比较两组患肢关节改良Ashworth分级(Modified Ashworth Scale,MAS)、美国国立卫生研究院卒中量表(National Institute of Health Stroke Scale,NIHSS)、Fugl-Meyer肢体运动功能量表(Fugl-Meyer Assessment,FMA)、Barthel指数(Barthel Index,BI)影响。结果治疗前,两组MAS评分、NIHSS评分、FMA评分、BI指数比较,差异无统计学意义(P均>0.05)。治疗后,研究组NIHSS评分(15.26±2.21)分、MAS评分(1.18±0.42)分,低于对照组的(17.21±2.70)分、(1.96±0.37)分,差异有统计学意义(t=2.680、6.683,P均<0.05)。治疗后,研究组FMA评分(59.90±8.23)分、BI指数(81.96±10.59)分,高于对照组的(55.50±3.69)分、(72.25±13.36)分,差异有统计学意义(t=2.340、2.708,P均<0.05)。结论急性大面积脑梗死患者开展开颅去大骨瓣减压联合综合康复治疗的效果显著,可改善神经受损情况,提升肢体功能、自理能力。展开更多
基金the Natural Science Foundation of Nei Monggol Autonomous Region, No. 980204
文摘BACKGROUND: Previous studies reported that frontal-temporal-parietal-occipital pathological changes and diseased range in the right cerbral hemisphere were correlated with neglect.But studies on the correlation of neglect with diseased region and area in patients who suffer from initial attack of single focus of cerebral infarction(CI) in left and right cerebral hemispheres are few.OBJECTIVE: To observe the status of neglect in patients who suffer from single focus of CI in cerebral hemisphere and analyze the correlation of neglect with diseased region and area of CI.DESIGN: Case analysis SETTING: Treatment Center for Cardiocerebrovascular Disease,Second Hospital of Xiamen city;Department of Neurology,First Hospital Affiliated to Baotou Medical College.PARTICIPANTS: All the CI patients hospitalized in the Department of Neurology.First Hospital Affiliated to Baotou Medical College from June 1998 to May 2001 were retrieved.Inclusive criteria:①Patients who suffered from initial attack of CI.which was confirmed by skull CT or MRI within 24 hours after onset and presented single focus in cerebral hemisphere. ②be conscious and could cooperate in the examination. ③did not receive formal education, but could do accounts and some simple writing and reading. ④Patients with homonymous hemianopia were excluded through the examination of perimeter.⑤Informed consents were obtained from all the patients.Among 67 patients who met the inclusive criteria.33 suffered from CI in the left cerebral hemisphere and 34 in the right cerebral hemisphere.METHODS:①Patients received neglect supplement examination and Chinese aphasia examination within 2.5 to 3 months after the attack of CI.The diagnostic criteria of neglect in the tests of line cancellation. 1ine bisection and copying the figures were as follows:In the line cancellation test based on the method of Albert.patients who could not cancel one or more lines were regarded as abnormal.In the line bisection test based on the method of Peter.patients who left deviated 1.16% or right deviated 2.51% were regarded as abnormal.In the test of copying the figures,round-shape,square,cruciform and other shapes were asked to be copied, defect appeared in the figure was regarded as abnormal.The diagnostic criteria of aphasia were according to the diagnostic method of Chinese aphasia examination and type identification flow-sheet of aphasia. Infarct area was calculated based on Palisino formula: infarct area=π/6×the longest diameter of infarct area×the widest diameter of infarct area×the number of CT positive layer.②Chi-square test was used for compadng the difference of measurement data.MAIN OUTCOME MEASURES:Diseased region and area of CI and their correlations with neglect.RESULTS:Sixty-seven patients were involved in result analysis.①The correlation of the occurrence of neglect with the diseased regions of CI:Neglect was not found in 33 patients with CI in left cerebral hemisphere.but was found in 7 of 34 patients with CI in right cerebral hemisphere.The diseased regions involved right temporoparietal region,temporal-parietal-occipital region,frontal-temporal-parietal region,frontal-temporal-parietal-occipital region,temporoparietal basal nucleus,basal nucleus and dorsal caudate putamen.②The correlation of the occurrence of neglect with diseased area:infarcl area≤30 cm3 was found in 2 patients with neglect(12.5%).infarct area at 31 to 60 cm3 in 1 patient with neglect(14.3%),infarct area≥61 cm3 in 4 patients with neglect (36.4%).There was no significant difference in infarct area among groups(P＞0.05).CONCLUSION:①Right cerebral hemisphere takes advantage in spatial attention.②Neglect is more possibly caused by the combined pathological changes in temporal and parietal lobe.Temporal and parietal lobes may not cause neglect independently,but the occurrence of neglect is not directly correlated with infarct area.
文摘Objective:To investigate the clinical effects of applying the magnetic resonance double mismatch technique to endovascular treatment of acute anterior circulation,large vessel occlusion with cerebral infarction in an unknown time window.Methods:The research work was carried out in our hospital,the work was carried out from November 2018 to November 2019,the patients with acute anterior circulation large vessel occlusion with cerebral infarction who were treated in our hospital during this period,100 patients,50 patients with an unknown time window and 50 patients with definite time window were selected,and they were named as the experimental and control groups,given different examination methods,were given to investigate the clinical treatment effect.Results:Patients’data on HIHSS score before treatment,the incidence of intracranial hemorrhage and rate of Mrs≤2 rating after 90 days of treatment were not significantly different(P>0.05),which was not meaningful.The differences in data between the two groups concerning HIHSS scores were relatively significant before,and after treatment(P<0.05).Conclusion:The magnetic resonance double mismatch technique will be applied in the endovascular treatment of acute anterior circulation large vessel occlusion with cerebral infarction of unknown time window.
文摘We reported a 50-year-old female patient with left supplementary motor area infarction who presented right lower limb apraxia and investigated the possible causes using transcranial magnetic stimulation. The patient was able to walk and climb stairs spontaneously without any assistance at 3 weeks after onset. However, she was unable to intentionally move her right lower limb although she understood what she supposed to do. The motor evoked potential evoked by transcranial magnetic stimulation from the right lower limb was within the normal range, indicating that the corticospinal tract innervating the right lower limb was uninjured. Thus, we thought that her motor dysfunction was not induced by motor weakness, and confirmed her symptoms as apraxia. In addition, these results also suggest that transcranial magnetic stimulation is helpful for diagnosing apraxia.
文摘Objective:Study the clinical effect of atorvastatin combined with clopidogrel on patients with progressive cerebral infarction of intracranial aortic stenosis.Methods: Chose eighty-eight patients with progressive cerebral infarction in our hospital from June 2014 to October 2015. They were randomly divided into study group and study group, 44 cases in each group. The patients in the control group were treated with oral clopidogrel. On the basis of this, the patients in the study group were treated with atorvastatin;all patients were treated for 4 weeks. Compared the total effective rate, adverse reaction rate, coagulation function index and blood lipid level between the two groups, and compared the NIHSS score and daily life ability (ADL) score between the two groups before and after treatment.Results: The total effective rate (90.90%) was significantly higher in the study group than in the control group (72.73%). After treatment, the NIHSS score of the study group was significantly lower than that of the control group. The levels of LDL-C, TG and TC in the study group were significantly lower than those in the control group, and HDL-C was significantly higher than that in the control group. There was no significant difference between the two groups.Conclusion: Clopidogrel combined with atorvastatin has a significant effect on the patients with intracranial large artery stenosis and improve the neurological function and quality of life. It is safe and reliable. It is worthy to be popularized.
文摘目的探究急性大面积脑梗死患者开展开颅去大骨瓣减压联合康复治疗的临床效果。方法选择2021年2月—2023年2月高密市人民医院收治的46例急性大面积脑梗死患者为研究对象,按随机数表法分为研究组和对照组,各23例。所有患者全部开展开颅去大骨瓣减压术治疗,对照组予以基础康复治疗,研究组予以综合康复治疗。比较两组患肢关节改良Ashworth分级(Modified Ashworth Scale,MAS)、美国国立卫生研究院卒中量表(National Institute of Health Stroke Scale,NIHSS)、Fugl-Meyer肢体运动功能量表(Fugl-Meyer Assessment,FMA)、Barthel指数(Barthel Index,BI)影响。结果治疗前,两组MAS评分、NIHSS评分、FMA评分、BI指数比较,差异无统计学意义(P均>0.05)。治疗后,研究组NIHSS评分(15.26±2.21)分、MAS评分(1.18±0.42)分,低于对照组的(17.21±2.70)分、(1.96±0.37)分,差异有统计学意义(t=2.680、6.683,P均<0.05)。治疗后,研究组FMA评分(59.90±8.23)分、BI指数(81.96±10.59)分,高于对照组的(55.50±3.69)分、(72.25±13.36)分,差异有统计学意义(t=2.340、2.708,P均<0.05)。结论急性大面积脑梗死患者开展开颅去大骨瓣减压联合综合康复治疗的效果显著,可改善神经受损情况,提升肢体功能、自理能力。
