Hydrodistillation has commonly been used to recover essential oil from various plant materials,including lavender(Lavandula officinalis) flowers.The main objectives of the present study were to model the kinetics of t...Hydrodistillation has commonly been used to recover essential oil from various plant materials,including lavender(Lavandula officinalis) flowers.The main objectives of the present study were to model the kinetics of the lavender essential oil(LEO) hydrodistillation using a phenomenological model,to evaluate the statistical significance of the hydromodule and hydrodistillation time on LEO yield combining a 4~2 full factorial design with the response surface methodology,to model statistically LEO yield by multiple non-linear regression and to determine the optimal process conditions that provided the maximum LEO yield.The fast-essential oil distillation(washing stage) in the initial period and the slow diffusion stage until the saturation occurring simultaneously were observed,justifying the use of the phenomenological model.With increasing the hydromodule,the saturation LEO yield and the washable fraction of the LEO decreased while the washing and diffusion rate constants increased.Knowledge of the LEO oil yield and the hydrodistillation kinetics is important from the techno-economical point of view.展开更多
Objective:In cardiovascular disease,a patient’s anxiety and depression can increase cardiac rehabilitation duration and recovery.Lavender aromatherapy as a non-pharmacological intervention effective in other contexts...Objective:In cardiovascular disease,a patient’s anxiety and depression can increase cardiac rehabilitation duration and recovery.Lavender aromatherapy as a non-pharmacological intervention effective in other contexts may be an efficient intervention to alleviating anxiety and depression in patients with Acute Coronary Syndrome(ACS).Methods:In this study,110 ACS patients were randomly assigned to two intervention and control groups.Inhalation of the lavender fragrance was prescribed for the intervention group and the drop of aromatic almond for the control group for 3 days.Results:The first-day anxiety and depression were significantly different in the two groups at 1 h and 9 h after the intervention.The’morning’s difference before the intervention was not significant,but it was substantial 1 h after the intervention.On the third morning of the intervention,this difference was confirmed.Conclusions:This study confirmed the effectiveness of lavender aromatherapy in reducing anxiety and depression in ACS patients.This’study’s results enable intensive care nurses to use aromatherapy with lavender oil as a non-pharmacological and cost-effective intervention to reduce their psychological tensions and increase patient satisfaction during hospitalization in the cardiac care units(CCU).展开更多
The contaminated soil has become a global problem for agricultural and environmental scientists. The soil as a natural resource is polluted by cadmium as a heavy metals from the different sources such as phosphorus fe...The contaminated soil has become a global problem for agricultural and environmental scientists. The soil as a natural resource is polluted by cadmium as a heavy metals from the different sources such as phosphorus fertilizers. The aim of this study was to investigate the biochar effect on absorption factor (AF) and translocation factor (TF) as the phytoremediation factors at different cadmium concentrations by lavender plant. The experiment was conducted in 3 × 4 factorial design including biochar treatment at the volumetric percentage ratio of 0%, 20% and 40% v/v and cadmium treatment at 0, 50, 100 and 150 mg Cd⋅kg−1 soil under greenhouse condition. The data analysis indicated that the biochar and cadmium treatments significantly (p ≤0.05) affected the plant dry biomass. The biochar addition caused to decrease the cadmium content of the root tissue. Biochar decreased cadmium uptake by lavender plant and also cadmium was accumulated by the root tissue and was prevented to translocate cadmium into the shoot tissue. Increasing cadmium concentration in soil caused an increase in cadmium adsorption factor however there was a significant decrease for translocation factor. It can be concluded to consider the possibility of planting the lavender with biochar application to amend the cadmium contaminated soils.展开更多
Near-infrared and mid-infrared spectroscopies were currently used to analyze natural compounds. During the last ten years various multiblocks methods were developed such as Concatenated PLS, Hierarchical-PLS (H-PLS), ...Near-infrared and mid-infrared spectroscopies were currently used to analyze natural compounds. During the last ten years various multiblocks methods were developed such as Concatenated PLS, Hierarchical-PLS (H-PLS), and MultiBlock-PLS (MB-PLS). These three algorithms were used to analyze 55 lavender (Lavandula angustifolia) essential oil samples. The results obtained were compared to the ones obtained respectively in NIR and MIR ranges. The accuracies of the models depend on the spectroscopic technique, pretreatment and the PLS methods. The results showed that the choice of the factor numbers used to build the multiblock models was the most important parameter for the H-PLS and MB-PLS methods.展开更多
to examine the effect of dry cupping therapy with lavender oil massage on the intensity of postpartum perineal pain.Methods:A 33 years old female had suffered with postpartum perineal pain.She experienced bilateral ep...to examine the effect of dry cupping therapy with lavender oil massage on the intensity of postpartum perineal pain.Methods:A 33 years old female had suffered with postpartum perineal pain.She experienced bilateral episiotomy on the third birth.Dry cupping therapy was administrated on selected areas two times.Before giving cupping therapy,at the 4th and 24th hours of birth was investigated effectiveness of dry cupping therapy on postpartum perineal pain based on the short-form of McGill pain scale.Results:According to the McGill pain scale,the mean of postpartum perineal pain intensity decreased from 37.9±10.5 before the dry cupping therapy with lavender oil massage to 12.1±5.3 in 4th hour,and 6.3±1.3.2 in 24th hour after delivery.The patient on cupping therapy with lavender oil message showed better results terms of pain intensity(P<0.001).Conclusion:The study confirmed that dry cupping therapy with lavender oil massage reduced postpartum perineal pain.In this regard,this intervention may be considered as affective method for reducing postpartum perineal pain.However,further trials are required to identify the effectiveness of this therapy regiment.展开更多
Background:Patie nts un dergo ing hemodialysis experie nces some symptoms.Pruritus,an xiety,and sleep quality are three of the most com mon symptoms.Eve n though some pharmacological treatme nts use to cope with these...Background:Patie nts un dergo ing hemodialysis experie nces some symptoms.Pruritus,an xiety,and sleep quality are three of the most com mon symptoms.Eve n though some pharmacological treatme nts use to cope with these symptoms,they are still experie need by the patie nts at a high level.Aim:This study aimed to determine the effect of lavender oil aromatherapy on pruritus,anxiety,and sleep quality of patients undergoing hemodialysis.Method:This randomized con trolled study was carried out betwee n December 2019 and March 2020.Eighty of 895 eligible patients were included in the study.Aromatherapy inhalation and massage together applied to the patients for six weeks.5D-Itch Scale,State Anxiety Inventory(SAI),and Richard Campbell Sleep Questio nn aire(RCSQ)were used for data collecti on.IBM SPSS 25.0 were used for statistical an alysis.Mann-Whit ney U,Wilcox on sig ned-ra nks test,and repeated measures-ANOVA tests were used to compare the difference between the groups and simple regression analysis to investigate the relationship between the dependent and independent variables.Results:Most of the patients were male(57.5%)and aged between 41 and 55 years(52.5%).There was significant difference in the mean scores of SAI(Pretest:44.02±5.33,Post-test:35.40±4.52,P=0.003),5D-Itch scale(Pretest:9.80±2.04,Post-test:7.00±2.31,P=0.001),and RCSQ(Pretest:17.11±40.30,Post-test:58.55±33.74,P=0.002)with in time in the in terve ntio n group.There was a statistically significant differenee between the groups regarding the mean scores of SAI(Intervention:35.40±4.52,Control:46.84±4.62,P=0.003),5D-Itch scale(Intervention:7.00±2.31,Control:8.96±2.05,P=0.004),and RCSQ(Intervention:58.55±33.74,Control:19.93±28.36,P=0.001)after the intervention.Conclusion:After six-weeks intervention,lavender aromatherapy was found an effective way to reduce pruritus,anxiety and to improve the sleep quality of patients undergoing hemodialysis.展开更多
In this paper, the preparation technique of lavender essential oil microcapsules and the construction method of aromatic textiles were expounded, and the research status of bed curtains and lavender microcapsules at h...In this paper, the preparation technique of lavender essential oil microcapsules and the construction method of aromatic textiles were expounded, and the research status of bed curtains and lavender microcapsules at home and abroad was analyzed and studied from the perspective of application in textiles. The application of lavender essential oil to bed curtains through the microcapsule technique was put forward to allow lavender essential oil to play its role of helping sleep in bed curtains. This paper expounded the material selection and preparation technique of lavender microcapsule agents, and put forward the preparation method of microcapsules with mixed solutions of pure Chinese medicine extracts and natural essences as core material and high-viscosity epoxy resin as wall materials. The post-processing techniques and the spray ironing method for clothing were studied and developed, and these techniques and methods were applied to bed curtains, and good results were obtained.展开更多
An effective in vitro propagation protocol was designed for Lavandula angustifolia Miller,a medicinal aromatic plant that is a prominent source of volatile organic compounds(VOCs).Murashige and Skoog media were supple...An effective in vitro propagation protocol was designed for Lavandula angustifolia Miller,a medicinal aromatic plant that is a prominent source of volatile organic compounds(VOCs).Murashige and Skoog media were supplemented with various concentrations of Plant Growth Regulators(PGRs),and the growth parameters of the nodal segments were examined.Nodal explants formed callus when they were supplemented with 2 mg/L of 6-Benzylaminopurine(BAP).The superior hormonal concentration of Murashige and Skoog(MS)media for the proliferation of shoots from callus cultures(39.33%)was 5 mg/L of 2-Isopentenyl adenine(2iP),and the favorable media for the growth of L.angustifolia callus cultures was 1 and 2 mg/L of BAP,with a 98%for-mation rate in each case.The callus cultures and in vitro propagated L.angustifolia seedlings obtained from var-ious PGR concentrations of MS media were exposed to qualitative and quantitative analysis in terms of phenolic profiles,flavonoids,High-performance liquid chromatography(HPLC)analysis of phenolic acids,and headspace-SPME analysis for volatiles.Such analysis revealed that micropropagated seedlings grown in media containing 1 mg/L of 6-Furfurylaminopurine(KIN)accumulated the highest yield(11.95±0.01 mg GAE/g)of phenolic acids.In contrast,the lowest concentration(2.17±0.04 mg GAE/g)was detected in 0.5 mg/L of BAP+0.5 mg/L of Naphthaleneacetic acid(NAA)media.The plantlets grown in 0.5 mg/L of BAP+0.5 mg/L of NAA media showed the highestflavonoid yield(31.67±0.06μg/g QE/g).In contrast,callus samples exhibited the lowest yield(11.59±0.02μg/g QE/g)offlavonoids in MS media supplemented with a concentration of 0.5 mg/L of BAP.HPLC analysis revealed the variability of phenolic acid contents within the callus cultures as well as plantlets,with gallic acid,4-OH benzoic acid,chlorogenic acid,vanillic acid,caffeic acid,cinnamic acid,and rosmarinic acid being the prominent constituents.The presence of twenty-two chemicals was revealed by headspace-SPME analysis.Eucalyptol,nonanal,borneol,carvone,andβ-caryophyllene were the most abundant.This study demonstrated that micropropagation of L.angustifolia may be an effective method to produce large numbers of genetically identical plantlets for the production of high-value bio compounds.展开更多
Objective:The objective of this study is to study the best inclusion technology of Lavender-and fennel-mixed volatile oil by beta?cyclodextrin(β-CD) and characterize the final product thereafter.Methods:Using the sat...Objective:The objective of this study is to study the best inclusion technology of Lavender-and fennel-mixed volatile oil by beta?cyclodextrin(β-CD) and characterize the final product thereafter.Methods:Using the saturated water solution method,the volatile β-CD inclusion complex was produced.The effect of volatile oil weight ratio,inclusion temperature and inclusion time on the inclusive quality was studied by measuring the yield of inclusion and inclusion rate of volatile oil as evaluation indexes.The preparation method of inclusion complex was then optimized by the Box-Behnken response surface method.The inclusion complex was characterized by ultraviolet spectrophotometry,thin-layer chromatography,thermogravimetry and differential thermal analysis,and the microscopic imaging method.Results:The optimized conditions were the weight ratio of β-CD to volatile oil was 8.13:1(g/ml).The inclusion temperature was 44°C.The inclusion time was 1 h.Conclusion:We were able to produce an inclusion complex with high inclusion rate of volatile oil and high yield of inclusion using the preparation method mentioned above.Furthermore,the method can also improve the stability of volatile oil in abnormal savda munziq.This study can provide a good reference for the development of new preparations.展开更多
Background: Major depressive disorder(MDD) accompanied by anxious distress is a chronic and disabling disorder. Its conventional drug therapies often have low patient compliance due to drug-related side effects. In Pe...Background: Major depressive disorder(MDD) accompanied by anxious distress is a chronic and disabling disorder. Its conventional drug therapies often have low patient compliance due to drug-related side effects. In Persian medicine, lavender-dodder syrup is one formula often recommended for such disorders.Objective: This study compares the effects of lavender-dodder syrup to the standard drug, citalopram, for treating MDD with anxious distress.Design, setting, participants and intervention: This six-week, double-blind, randomized, clinical trial was carried out in a psychiatric outpatient clinic. During the six-week intervention period, patients in citalopram group received citalopram tablets 20 mg/d plus 5 mL placebo syrup every 12 h;patients in group B received placebo tablets once daily plus 5 mL of lavender-dodder herbal syrup every 12 h.Main outcome measures: Primary outcome measures, depression and anxiety, were evaluated using the Hamilton Depression/Anxiety Rating Scales, and were scored at the beginning of the study and at weeks three and six. Secondary outcome measures including response to treatment and remission rates were also compared between the two groups.Results: Fifty-six participants with MDD and anxious distress were randomly assigned to two groups.Mean depression scores significantly decreased in citalopram and herbal groups at weeks three and six(time effect: P < 0.001), although the observed changes were not significantly different between the groups(intervention effect: P = 0.61). Mean anxiety scores were not significantly different between the two groups at week three(P = 0.75). However, at the end of week six, the observed decrease was significantly higher in the herbal syrup group than the citalopram group(intervention effect: P = 0.007).Conclusion: The herbal syrup is an effective and tolerable supplement for treating MDD with anxious distress.Trial registration number: IRCT2016102430459 N1 on Iranian Registry of Clinical Trials.展开更多
This research aims to perform an energy input-output analysis of lavender plant production in Isparta Province of Turkey.In order to determine the energy use efficiency of lavender plant,experiments and trials have be...This research aims to perform an energy input-output analysis of lavender plant production in Isparta Province of Turkey.In order to determine the energy use efficiency of lavender plant,experiments and trials have been conducted on 10 lavender farms around Keçiborlu region of Isparta Province.Keçiborlu region of Isparta Province is an important location for lavender production.On these 10 lavender farms,energy input-output has also been calculated through trial and measurement methods during the production season of 2013.In lavender production,energy input has been calculated as 6336.50 MJ/hm^(2)and energy output has been calculated as 17528.81 MJ/hm^(2).Energy inputs consist of chemical fertilizers energy by 52.88%,diesel energy by 33.32%,machinery energy by 9.72%,human labour energy by 2.85%and chemicals by 1.23%.Energy use efficiency,energy productivity,specific energy and net energy in lavender production have been calculated as 2.77;0.75 kg/MJ,1.34 MJ/kg and 11192.31 MJ/hm^(2),respectively.Benefit-cost ratio has been calculated as 3.41 by dividing the gross value of production by the total cost of production per hectare.展开更多
Background Neonatal pain may affect long-term neurodevelopment and must be treated.Frenotomy is a painful procedure wherein a common strategy to relieve pain(sucking)cannot be used because the technique is performed o...Background Neonatal pain may affect long-term neurodevelopment and must be treated.Frenotomy is a painful procedure wherein a common strategy to relieve pain(sucking)cannot be used because the technique is performed on the tongue.Lavender essential oil(LEO)has sedative and antispasmodic properties and has been successfully used to treat pain during heel puncture and vaccination.Our aim was to demonstrate if the use of inhaled LEO is effective in reducing pain during frenotomy in healthy,full-term neonates.Methods We conducted a randomized clinical trial in neonates who underwent a frenotomy between August 2020 and April 2021.We assessed pain using pre and post-procedure heart rate and oxygen saturation,crying time and Neonatal Infant Pain Scale(NIPS)score.Patients with type 3 tongue tie were randomized into the“experimental group”and“control group”.In both groups,we performed swaddling,administered oral sucrose,and let the newborn suck for two minutes.In the experimental group,we also placed a gauze pad with one drop of LEO under the neonate’s nose for two minutes prior to and during the frenotomy.Results We enrolled 142 patients(71 per group).The experimental group showed significantly lower NIPS scores(1.88 vs 2.92)and cried almost half the amount of time(14.8 vs.24.6 seconds,P=0.006).Comparing with the control group,we observed no side effects in either of the groups.Conclusions We observed a significant decrease in crying time and lower NIPS scores in the neonates who received inhaled LEO and underwent a frenotomy for type 3 tongue-ties.Thus,we recommend using inhaled LEO during neonatal frenotomies.展开更多
Background: Conscious patients admitted to intensive care units(ICUs) suffer from pain for various reasons, which can affect their recovery process.Objective: The present study compared the effects of aromatherapy wit...Background: Conscious patients admitted to intensive care units(ICUs) suffer from pain for various reasons, which can affect their recovery process.Objective: The present study compared the effects of aromatherapy with Citrus aurantium and lavender essential oils against placebo for reducing pain in conscious intensive care patients.Design, setting, participants and interventions: This study was a parallel randomized placebo-controlled trial. The ICUs of two educational hospitals in Kerman in Southeastern Iran were the study setting.One hundred and fifty conscious intensive care patients were randomly divided into three groups using a stratified block randomization method. Two groups received aromatherapy with essential oils: one with lavender and the other with C. aurantium;these patients received a 30-minute therapy session using their assigned essential oil on the second day of their intensive care stay. The placebo group used 5 drops of normal saline instead of essential oil during their session.Main outcome measures: Patient’s pain was assessed using a visual analog scale before the aromatherapy intervention, as well as immediately after and one and three hours after intervention.Results: The mean pain score of the lavender group was 40.01 before the aromatherapy intervention and fell to 39.40, 30.60 and 23.68 immediately after the intervention, and at hour one and three postintervention, respectively. The mean pain score of the C. aurantium group was 45.48 before the intervention and was reduced to 32.34 at three hours after the intervention. The mean pain of the placebo group decreased from 42.80 before the intervention to 35.20 at three hours after the intervention. Pain scores of all groups decreased during the study(P < 0.001). The mean pain of the lavender group was significantly lower than that of the placebo group at three hours after the intervention.Conclusion: The results of this study showed that aromatherapy with lavender essential oil reduced pain in conscious ICU patients. Our data could not justify the use of C. aurantium for reducing pain in this population.展开更多
Essential oils of pure lavender and lavender blends have been employed as potential anxiolytic aromas in aromatherapy, but a direct comparison of their effectiveness is lacking. The current study investigated the effe...Essential oils of pure lavender and lavender blends have been employed as potential anxiolytic aromas in aromatherapy, but a direct comparison of their effectiveness is lacking. The current study investigated the effects of aroma on induced anxiety in non-clinical adults, comparing pure lavender, a commercially available blend and a no aroma control. An experimental, quantitative, mixed factorial design with an opportunity sample of 60 participants was employed. Participants were randomly allocated to three equal groups, one tested in a room infused with lavender aroma, the second with the doTerra Peace<sup>®</sup> blend, and the third free from any aroma. Participants’ state anxiety scores were measured before and after a novel video-based anxiety induction procedure. Data analysis revealed that the anxiety induction was successful and that both aromas delivered small to medium-sized buffering effects compared to no aroma. The findings add to a small body of research in an area where the practice is global yet has limited scientific evaluation. Future studies utilising brain imaging and blood serum analysis to investigate the anxiolytic mechanism of aromas would be beneficial to further our understanding.展开更多
L.stoechas subsp.luisieri is one of the five spontaneous species of the genus Lavandula that occurs spontaneously in Portugal.The chemical profile and antifungal activity of L.stoechas subsp.luisieri essential oils we...L.stoechas subsp.luisieri is one of the five spontaneous species of the genus Lavandula that occurs spontaneously in Portugal.The chemical profile and antifungal activity of L.stoechas subsp.luisieri essential oils were investigated.The essential oil of two phenological stages was isolated by hydrodistillation and their chemical components analyzed by GC-FID/GC-MS.The minimum inhibitory concentration(MIC)and the minimum fungicidal concentration(MFC)of both essential oils were determinate to verify antifungal activity against different strains of fungi isolated from strawberry tree.The fungi tested were Aspergillus carbonarius,Rhizopus stolonifer,Penicillium brevicompactum,Aureobasidium pullulans and Saccothecium rubi.Essential oils were characterized by a high percentage of oxygenated monoterpenes(46-64%)such as trans-α-necrodyl acetate(12.58%),fenchone(5.97%),1,8-cineole(4.84%)and 5-methylene-2,3,4,4-tetramethylcyclopenten-2-enone(10.97%)were the major compounds in essential oil from dormancy stage,while the main compounds in flowering stage were trans-α-necrodyl acetate(26.90%),trans-α-necrodol(13.02%),lavandulyl acetate(6.53%)and linalool(5.82%).A strong antifungal activity of the essential oils was found against all strains,with MIC and MFC values ranged from 0.07-0.29μL/mL and 0.58-9.33μL/mL,respectively.展开更多
基金funded by the Ministry of Education, Science and Technological Development of the Republic of Serbia (Project assigned to the Faculty of Technology, Leskovac, University of No, Research Group Ⅲ 45001, No. 451-03-68/2020-14/200133)。
文摘Hydrodistillation has commonly been used to recover essential oil from various plant materials,including lavender(Lavandula officinalis) flowers.The main objectives of the present study were to model the kinetics of the lavender essential oil(LEO) hydrodistillation using a phenomenological model,to evaluate the statistical significance of the hydromodule and hydrodistillation time on LEO yield combining a 4~2 full factorial design with the response surface methodology,to model statistically LEO yield by multiple non-linear regression and to determine the optimal process conditions that provided the maximum LEO yield.The fast-essential oil distillation(washing stage) in the initial period and the slow diffusion stage until the saturation occurring simultaneously were observed,justifying the use of the phenomenological model.With increasing the hydromodule,the saturation LEO yield and the washable fraction of the LEO decreased while the washing and diffusion rate constants increased.Knowledge of the LEO oil yield and the hydrodistillation kinetics is important from the techno-economical point of view.
文摘Objective:In cardiovascular disease,a patient’s anxiety and depression can increase cardiac rehabilitation duration and recovery.Lavender aromatherapy as a non-pharmacological intervention effective in other contexts may be an efficient intervention to alleviating anxiety and depression in patients with Acute Coronary Syndrome(ACS).Methods:In this study,110 ACS patients were randomly assigned to two intervention and control groups.Inhalation of the lavender fragrance was prescribed for the intervention group and the drop of aromatic almond for the control group for 3 days.Results:The first-day anxiety and depression were significantly different in the two groups at 1 h and 9 h after the intervention.The’morning’s difference before the intervention was not significant,but it was substantial 1 h after the intervention.On the third morning of the intervention,this difference was confirmed.Conclusions:This study confirmed the effectiveness of lavender aromatherapy in reducing anxiety and depression in ACS patients.This’study’s results enable intensive care nurses to use aromatherapy with lavender oil as a non-pharmacological and cost-effective intervention to reduce their psychological tensions and increase patient satisfaction during hospitalization in the cardiac care units(CCU).
文摘The contaminated soil has become a global problem for agricultural and environmental scientists. The soil as a natural resource is polluted by cadmium as a heavy metals from the different sources such as phosphorus fertilizers. The aim of this study was to investigate the biochar effect on absorption factor (AF) and translocation factor (TF) as the phytoremediation factors at different cadmium concentrations by lavender plant. The experiment was conducted in 3 × 4 factorial design including biochar treatment at the volumetric percentage ratio of 0%, 20% and 40% v/v and cadmium treatment at 0, 50, 100 and 150 mg Cd⋅kg−1 soil under greenhouse condition. The data analysis indicated that the biochar and cadmium treatments significantly (p ≤0.05) affected the plant dry biomass. The biochar addition caused to decrease the cadmium content of the root tissue. Biochar decreased cadmium uptake by lavender plant and also cadmium was accumulated by the root tissue and was prevented to translocate cadmium into the shoot tissue. Increasing cadmium concentration in soil caused an increase in cadmium adsorption factor however there was a significant decrease for translocation factor. It can be concluded to consider the possibility of planting the lavender with biochar application to amend the cadmium contaminated soils.
文摘Near-infrared and mid-infrared spectroscopies were currently used to analyze natural compounds. During the last ten years various multiblocks methods were developed such as Concatenated PLS, Hierarchical-PLS (H-PLS), and MultiBlock-PLS (MB-PLS). These three algorithms were used to analyze 55 lavender (Lavandula angustifolia) essential oil samples. The results obtained were compared to the ones obtained respectively in NIR and MIR ranges. The accuracies of the models depend on the spectroscopic technique, pretreatment and the PLS methods. The results showed that the choice of the factor numbers used to build the multiblock models was the most important parameter for the H-PLS and MB-PLS methods.
文摘to examine the effect of dry cupping therapy with lavender oil massage on the intensity of postpartum perineal pain.Methods:A 33 years old female had suffered with postpartum perineal pain.She experienced bilateral episiotomy on the third birth.Dry cupping therapy was administrated on selected areas two times.Before giving cupping therapy,at the 4th and 24th hours of birth was investigated effectiveness of dry cupping therapy on postpartum perineal pain based on the short-form of McGill pain scale.Results:According to the McGill pain scale,the mean of postpartum perineal pain intensity decreased from 37.9±10.5 before the dry cupping therapy with lavender oil massage to 12.1±5.3 in 4th hour,and 6.3±1.3.2 in 24th hour after delivery.The patient on cupping therapy with lavender oil message showed better results terms of pain intensity(P<0.001).Conclusion:The study confirmed that dry cupping therapy with lavender oil massage reduced postpartum perineal pain.In this regard,this intervention may be considered as affective method for reducing postpartum perineal pain.However,further trials are required to identify the effectiveness of this therapy regiment.
文摘Background:Patie nts un dergo ing hemodialysis experie nces some symptoms.Pruritus,an xiety,and sleep quality are three of the most com mon symptoms.Eve n though some pharmacological treatme nts use to cope with these symptoms,they are still experie need by the patie nts at a high level.Aim:This study aimed to determine the effect of lavender oil aromatherapy on pruritus,anxiety,and sleep quality of patients undergoing hemodialysis.Method:This randomized con trolled study was carried out betwee n December 2019 and March 2020.Eighty of 895 eligible patients were included in the study.Aromatherapy inhalation and massage together applied to the patients for six weeks.5D-Itch Scale,State Anxiety Inventory(SAI),and Richard Campbell Sleep Questio nn aire(RCSQ)were used for data collecti on.IBM SPSS 25.0 were used for statistical an alysis.Mann-Whit ney U,Wilcox on sig ned-ra nks test,and repeated measures-ANOVA tests were used to compare the difference between the groups and simple regression analysis to investigate the relationship between the dependent and independent variables.Results:Most of the patients were male(57.5%)and aged between 41 and 55 years(52.5%).There was significant difference in the mean scores of SAI(Pretest:44.02±5.33,Post-test:35.40±4.52,P=0.003),5D-Itch scale(Pretest:9.80±2.04,Post-test:7.00±2.31,P=0.001),and RCSQ(Pretest:17.11±40.30,Post-test:58.55±33.74,P=0.002)with in time in the in terve ntio n group.There was a statistically significant differenee between the groups regarding the mean scores of SAI(Intervention:35.40±4.52,Control:46.84±4.62,P=0.003),5D-Itch scale(Intervention:7.00±2.31,Control:8.96±2.05,P=0.004),and RCSQ(Intervention:58.55±33.74,Control:19.93±28.36,P=0.001)after the intervention.Conclusion:After six-weeks intervention,lavender aromatherapy was found an effective way to reduce pruritus,anxiety and to improve the sleep quality of patients undergoing hemodialysis.
基金Supported by Undergraduate Training Program for Innovation and Entrepreneurship of Guangxi University of Chinese Medicine in 2023(S202310600084)。
文摘In this paper, the preparation technique of lavender essential oil microcapsules and the construction method of aromatic textiles were expounded, and the research status of bed curtains and lavender microcapsules at home and abroad was analyzed and studied from the perspective of application in textiles. The application of lavender essential oil to bed curtains through the microcapsule technique was put forward to allow lavender essential oil to play its role of helping sleep in bed curtains. This paper expounded the material selection and preparation technique of lavender microcapsule agents, and put forward the preparation method of microcapsules with mixed solutions of pure Chinese medicine extracts and natural essences as core material and high-viscosity epoxy resin as wall materials. The post-processing techniques and the spray ironing method for clothing were studied and developed, and these techniques and methods were applied to bed curtains, and good results were obtained.
文摘An effective in vitro propagation protocol was designed for Lavandula angustifolia Miller,a medicinal aromatic plant that is a prominent source of volatile organic compounds(VOCs).Murashige and Skoog media were supplemented with various concentrations of Plant Growth Regulators(PGRs),and the growth parameters of the nodal segments were examined.Nodal explants formed callus when they were supplemented with 2 mg/L of 6-Benzylaminopurine(BAP).The superior hormonal concentration of Murashige and Skoog(MS)media for the proliferation of shoots from callus cultures(39.33%)was 5 mg/L of 2-Isopentenyl adenine(2iP),and the favorable media for the growth of L.angustifolia callus cultures was 1 and 2 mg/L of BAP,with a 98%for-mation rate in each case.The callus cultures and in vitro propagated L.angustifolia seedlings obtained from var-ious PGR concentrations of MS media were exposed to qualitative and quantitative analysis in terms of phenolic profiles,flavonoids,High-performance liquid chromatography(HPLC)analysis of phenolic acids,and headspace-SPME analysis for volatiles.Such analysis revealed that micropropagated seedlings grown in media containing 1 mg/L of 6-Furfurylaminopurine(KIN)accumulated the highest yield(11.95±0.01 mg GAE/g)of phenolic acids.In contrast,the lowest concentration(2.17±0.04 mg GAE/g)was detected in 0.5 mg/L of BAP+0.5 mg/L of Naphthaleneacetic acid(NAA)media.The plantlets grown in 0.5 mg/L of BAP+0.5 mg/L of NAA media showed the highestflavonoid yield(31.67±0.06μg/g QE/g).In contrast,callus samples exhibited the lowest yield(11.59±0.02μg/g QE/g)offlavonoids in MS media supplemented with a concentration of 0.5 mg/L of BAP.HPLC analysis revealed the variability of phenolic acid contents within the callus cultures as well as plantlets,with gallic acid,4-OH benzoic acid,chlorogenic acid,vanillic acid,caffeic acid,cinnamic acid,and rosmarinic acid being the prominent constituents.The presence of twenty-two chemicals was revealed by headspace-SPME analysis.Eucalyptol,nonanal,borneol,carvone,andβ-caryophyllene were the most abundant.This study demonstrated that micropropagation of L.angustifolia may be an effective method to produce large numbers of genetically identical plantlets for the production of high-value bio compounds.
基金supported by the National Natural Science Foundation of China(no:81660667)
文摘Objective:The objective of this study is to study the best inclusion technology of Lavender-and fennel-mixed volatile oil by beta?cyclodextrin(β-CD) and characterize the final product thereafter.Methods:Using the saturated water solution method,the volatile β-CD inclusion complex was produced.The effect of volatile oil weight ratio,inclusion temperature and inclusion time on the inclusive quality was studied by measuring the yield of inclusion and inclusion rate of volatile oil as evaluation indexes.The preparation method of inclusion complex was then optimized by the Box-Behnken response surface method.The inclusion complex was characterized by ultraviolet spectrophotometry,thin-layer chromatography,thermogravimetry and differential thermal analysis,and the microscopic imaging method.Results:The optimized conditions were the weight ratio of β-CD to volatile oil was 8.13:1(g/ml).The inclusion temperature was 44°C.The inclusion time was 1 h.Conclusion:We were able to produce an inclusion complex with high inclusion rate of volatile oil and high yield of inclusion using the preparation method mentioned above.Furthermore,the method can also improve the stability of volatile oil in abnormal savda munziq.This study can provide a good reference for the development of new preparations.
基金a part of a PhD thesis by Dr. Toktam Sadat Firoozeei,supported by Tehran University of Medical Sciences,in order to fulfil the requirements of a PhD degree in Persian medicine。
文摘Background: Major depressive disorder(MDD) accompanied by anxious distress is a chronic and disabling disorder. Its conventional drug therapies often have low patient compliance due to drug-related side effects. In Persian medicine, lavender-dodder syrup is one formula often recommended for such disorders.Objective: This study compares the effects of lavender-dodder syrup to the standard drug, citalopram, for treating MDD with anxious distress.Design, setting, participants and intervention: This six-week, double-blind, randomized, clinical trial was carried out in a psychiatric outpatient clinic. During the six-week intervention period, patients in citalopram group received citalopram tablets 20 mg/d plus 5 mL placebo syrup every 12 h;patients in group B received placebo tablets once daily plus 5 mL of lavender-dodder herbal syrup every 12 h.Main outcome measures: Primary outcome measures, depression and anxiety, were evaluated using the Hamilton Depression/Anxiety Rating Scales, and were scored at the beginning of the study and at weeks three and six. Secondary outcome measures including response to treatment and remission rates were also compared between the two groups.Results: Fifty-six participants with MDD and anxious distress were randomly assigned to two groups.Mean depression scores significantly decreased in citalopram and herbal groups at weeks three and six(time effect: P < 0.001), although the observed changes were not significantly different between the groups(intervention effect: P = 0.61). Mean anxiety scores were not significantly different between the two groups at week three(P = 0.75). However, at the end of week six, the observed decrease was significantly higher in the herbal syrup group than the citalopram group(intervention effect: P = 0.007).Conclusion: The herbal syrup is an effective and tolerable supplement for treating MDD with anxious distress.Trial registration number: IRCT2016102430459 N1 on Iranian Registry of Clinical Trials.
文摘This research aims to perform an energy input-output analysis of lavender plant production in Isparta Province of Turkey.In order to determine the energy use efficiency of lavender plant,experiments and trials have been conducted on 10 lavender farms around Keçiborlu region of Isparta Province.Keçiborlu region of Isparta Province is an important location for lavender production.On these 10 lavender farms,energy input-output has also been calculated through trial and measurement methods during the production season of 2013.In lavender production,energy input has been calculated as 6336.50 MJ/hm^(2)and energy output has been calculated as 17528.81 MJ/hm^(2).Energy inputs consist of chemical fertilizers energy by 52.88%,diesel energy by 33.32%,machinery energy by 9.72%,human labour energy by 2.85%and chemicals by 1.23%.Energy use efficiency,energy productivity,specific energy and net energy in lavender production have been calculated as 2.77;0.75 kg/MJ,1.34 MJ/kg and 11192.31 MJ/hm^(2),respectively.Benefit-cost ratio has been calculated as 3.41 by dividing the gross value of production by the total cost of production per hectare.
文摘Background Neonatal pain may affect long-term neurodevelopment and must be treated.Frenotomy is a painful procedure wherein a common strategy to relieve pain(sucking)cannot be used because the technique is performed on the tongue.Lavender essential oil(LEO)has sedative and antispasmodic properties and has been successfully used to treat pain during heel puncture and vaccination.Our aim was to demonstrate if the use of inhaled LEO is effective in reducing pain during frenotomy in healthy,full-term neonates.Methods We conducted a randomized clinical trial in neonates who underwent a frenotomy between August 2020 and April 2021.We assessed pain using pre and post-procedure heart rate and oxygen saturation,crying time and Neonatal Infant Pain Scale(NIPS)score.Patients with type 3 tongue tie were randomized into the“experimental group”and“control group”.In both groups,we performed swaddling,administered oral sucrose,and let the newborn suck for two minutes.In the experimental group,we also placed a gauze pad with one drop of LEO under the neonate’s nose for two minutes prior to and during the frenotomy.Results We enrolled 142 patients(71 per group).The experimental group showed significantly lower NIPS scores(1.88 vs 2.92)and cried almost half the amount of time(14.8 vs.24.6 seconds,P=0.006).Comparing with the control group,we observed no side effects in either of the groups.Conclusions We observed a significant decrease in crying time and lower NIPS scores in the neonates who received inhaled LEO and underwent a frenotomy for type 3 tongue-ties.Thus,we recommend using inhaled LEO during neonatal frenotomies.
文摘Background: Conscious patients admitted to intensive care units(ICUs) suffer from pain for various reasons, which can affect their recovery process.Objective: The present study compared the effects of aromatherapy with Citrus aurantium and lavender essential oils against placebo for reducing pain in conscious intensive care patients.Design, setting, participants and interventions: This study was a parallel randomized placebo-controlled trial. The ICUs of two educational hospitals in Kerman in Southeastern Iran were the study setting.One hundred and fifty conscious intensive care patients were randomly divided into three groups using a stratified block randomization method. Two groups received aromatherapy with essential oils: one with lavender and the other with C. aurantium;these patients received a 30-minute therapy session using their assigned essential oil on the second day of their intensive care stay. The placebo group used 5 drops of normal saline instead of essential oil during their session.Main outcome measures: Patient’s pain was assessed using a visual analog scale before the aromatherapy intervention, as well as immediately after and one and three hours after intervention.Results: The mean pain score of the lavender group was 40.01 before the aromatherapy intervention and fell to 39.40, 30.60 and 23.68 immediately after the intervention, and at hour one and three postintervention, respectively. The mean pain score of the C. aurantium group was 45.48 before the intervention and was reduced to 32.34 at three hours after the intervention. The mean pain of the placebo group decreased from 42.80 before the intervention to 35.20 at three hours after the intervention. Pain scores of all groups decreased during the study(P < 0.001). The mean pain of the lavender group was significantly lower than that of the placebo group at three hours after the intervention.Conclusion: The results of this study showed that aromatherapy with lavender essential oil reduced pain in conscious ICU patients. Our data could not justify the use of C. aurantium for reducing pain in this population.
文摘Essential oils of pure lavender and lavender blends have been employed as potential anxiolytic aromas in aromatherapy, but a direct comparison of their effectiveness is lacking. The current study investigated the effects of aroma on induced anxiety in non-clinical adults, comparing pure lavender, a commercially available blend and a no aroma control. An experimental, quantitative, mixed factorial design with an opportunity sample of 60 participants was employed. Participants were randomly allocated to three equal groups, one tested in a room infused with lavender aroma, the second with the doTerra Peace<sup>®</sup> blend, and the third free from any aroma. Participants’ state anxiety scores were measured before and after a novel video-based anxiety induction procedure. Data analysis revealed that the anxiety induction was successful and that both aromas delivered small to medium-sized buffering effects compared to no aroma. The findings add to a small body of research in an area where the practice is global yet has limited scientific evaluation. Future studies utilising brain imaging and blood serum analysis to investigate the anxiolytic mechanism of aromas would be beneficial to further our understanding.
基金CENTRO 2020,PROVERE-Operational Program CENTRO-04-3928-FEDER-000009,Strawberry TreeInnovation Platform Action,Portugal 2020 and European Union by FEDER and by COOP4PAM-Cooperar para crescer no setor das plantas aromáticas e medicinais-Projeto INTERREG/Programa Espanha-Portugal(POCTEP),0665_COOP4PAM_4_P.
文摘L.stoechas subsp.luisieri is one of the five spontaneous species of the genus Lavandula that occurs spontaneously in Portugal.The chemical profile and antifungal activity of L.stoechas subsp.luisieri essential oils were investigated.The essential oil of two phenological stages was isolated by hydrodistillation and their chemical components analyzed by GC-FID/GC-MS.The minimum inhibitory concentration(MIC)and the minimum fungicidal concentration(MFC)of both essential oils were determinate to verify antifungal activity against different strains of fungi isolated from strawberry tree.The fungi tested were Aspergillus carbonarius,Rhizopus stolonifer,Penicillium brevicompactum,Aureobasidium pullulans and Saccothecium rubi.Essential oils were characterized by a high percentage of oxygenated monoterpenes(46-64%)such as trans-α-necrodyl acetate(12.58%),fenchone(5.97%),1,8-cineole(4.84%)and 5-methylene-2,3,4,4-tetramethylcyclopenten-2-enone(10.97%)were the major compounds in essential oil from dormancy stage,while the main compounds in flowering stage were trans-α-necrodyl acetate(26.90%),trans-α-necrodol(13.02%),lavandulyl acetate(6.53%)and linalool(5.82%).A strong antifungal activity of the essential oils was found against all strains,with MIC and MFC values ranged from 0.07-0.29μL/mL and 0.58-9.33μL/mL,respectively.
