AIM:To evaluate the effect of lid scrubbing using a gel combining different natural extracts on ocular signs and symptoms of dry eye patients.METHODS:A retrospective study was performed on 19 dry eye patients(51.1...AIM:To evaluate the effect of lid scrubbing using a gel combining different natural extracts on ocular signs and symptoms of dry eye patients.METHODS:A retrospective study was performed on 19 dry eye patients(51.1±16.0y).Non-invasive tear break-up time,tear meniscus height,meibomian gland loss,lipid layer thickness,conjunctival redness,corneal staining,ocular surface disease index(OSDI),and ocular pain intensity were measured before(baseline),1wk,and 2mo after lid scrubbing with a gel containing different natural extracts(okra extract,aloe vera leaf juice,hydrolysed soy protein,caffeine,citrus unshiu peel extract,and raspberry seed oil).RESULTS:Compared with the baseline,there was a statistically significant improvement in both first(P=0.048)and average(P=0.026)non-invasive tear break-up time 2mo after treatment,as well as in corneal staining(P=0.043,0.012),OSDI(P<0.001),and ocular pain intensity(P<0.001)after 1wk and 2mo.In addition,there was no correlation between ocular signs and symptoms.CONCLUSION:The lid scrubbing with a gel combining different natural extracts show beneficial effects on tear film stability,corneal damage,and ocular symptoms,which is the reason why this therapeutic procedure is proposed as an alternative for dry eye management.However,it is not possible to attribute this beneficial effect solely to the presence of the natural extracts in the gel,primarily due to the absence of a negative control group.展开更多
The purpose of this paper is to investigate the simulation of mixed convection in a lid-driven wavy enclosure with blocks positioned at various positions. This study also examined the impact of the longitudinal positi...The purpose of this paper is to investigate the simulation of mixed convection in a lid-driven wavy enclosure with blocks positioned at various positions. This study also examined the impact of the longitudinal position of the heated block on heat transfer enhancement. The Galerkin weighted residual finite element method is employed to computationally solve the governing equations of Navier-Stokes, thermal energy, and mass conservation. The enclosure consists of two square heated blocks strategically placed at different heights—firstly, one set is closer to the bottom surface;secondly, one set is nearer to the middle area and finally, one set is closer to the upper undulating surface of the enclosure. The wavy top wall’s thermal insulation, along with active heating of the bottom wall and blocks, generates a dynamic convective atmosphere. In addition, the left wall ascends as the right wall falls, causing the flow formed by the lid. The study investigates the impact of the Richardson number on many factors, such as streamlines, isotherms, dimensionless temperature, velocity profiles, and average Nusselt numbers. These impacts are depicted through graphical illustrations. In all instances, two counter-rotating eddies were generated within the cage. Higher rotating speed consistently leads to improved performance, irrespective of other characteristics. Furthermore, an ideal amalgamation of the regulating factors would lead to increased heat transmission.展开更多
文摘AIM:To evaluate the effect of lid scrubbing using a gel combining different natural extracts on ocular signs and symptoms of dry eye patients.METHODS:A retrospective study was performed on 19 dry eye patients(51.1±16.0y).Non-invasive tear break-up time,tear meniscus height,meibomian gland loss,lipid layer thickness,conjunctival redness,corneal staining,ocular surface disease index(OSDI),and ocular pain intensity were measured before(baseline),1wk,and 2mo after lid scrubbing with a gel containing different natural extracts(okra extract,aloe vera leaf juice,hydrolysed soy protein,caffeine,citrus unshiu peel extract,and raspberry seed oil).RESULTS:Compared with the baseline,there was a statistically significant improvement in both first(P=0.048)and average(P=0.026)non-invasive tear break-up time 2mo after treatment,as well as in corneal staining(P=0.043,0.012),OSDI(P<0.001),and ocular pain intensity(P<0.001)after 1wk and 2mo.In addition,there was no correlation between ocular signs and symptoms.CONCLUSION:The lid scrubbing with a gel combining different natural extracts show beneficial effects on tear film stability,corneal damage,and ocular symptoms,which is the reason why this therapeutic procedure is proposed as an alternative for dry eye management.However,it is not possible to attribute this beneficial effect solely to the presence of the natural extracts in the gel,primarily due to the absence of a negative control group.
文摘The purpose of this paper is to investigate the simulation of mixed convection in a lid-driven wavy enclosure with blocks positioned at various positions. This study also examined the impact of the longitudinal position of the heated block on heat transfer enhancement. The Galerkin weighted residual finite element method is employed to computationally solve the governing equations of Navier-Stokes, thermal energy, and mass conservation. The enclosure consists of two square heated blocks strategically placed at different heights—firstly, one set is closer to the bottom surface;secondly, one set is nearer to the middle area and finally, one set is closer to the upper undulating surface of the enclosure. The wavy top wall’s thermal insulation, along with active heating of the bottom wall and blocks, generates a dynamic convective atmosphere. In addition, the left wall ascends as the right wall falls, causing the flow formed by the lid. The study investigates the impact of the Richardson number on many factors, such as streamlines, isotherms, dimensionless temperature, velocity profiles, and average Nusselt numbers. These impacts are depicted through graphical illustrations. In all instances, two counter-rotating eddies were generated within the cage. Higher rotating speed consistently leads to improved performance, irrespective of other characteristics. Furthermore, an ideal amalgamation of the regulating factors would lead to increased heat transmission.
