UK manufacturers experienced a challenging start to 2024,with sales in the first quarter(Q1)down 10 per cent on the previous quarter,according to a report by Unleashed.However,year-on-year growth showed a modest incre...UK manufacturers experienced a challenging start to 2024,with sales in the first quarter(Q1)down 10 per cent on the previous quarter,according to a report by Unleashed.However,year-on-year growth showed a modest increase of 2 per cent,reflecting the Bank of England’s assessment of weak growth in the manufacturing sector.展开更多
One of the core competencies of a supermarket lies in its branding.With the continuous development of the market economy and the ongoing evolution of consumer demand,private brands have progressively emerged as signif...One of the core competencies of a supermarket lies in its branding.With the continuous development of the market economy and the ongoing evolution of consumer demand,private brands have progressively emerged as significant contributors to supermarket growth.However,a pivotal developmental challenge for supermarkets is navigating the innovative decision-making process between private brands and designated manufacturers.This paper aims to investigate the innovative decisions between private brands and designated manufacturers,along with the relevant promotional strategies employed during entry into the United States market.展开更多
The potential Chinese market is increasingly attracting the major PC producers of the world, against a background of a forecast that the global PC market is shrinking. According to an analysis of experts with the Mini...The potential Chinese market is increasingly attracting the major PC producers of the world, against a background of a forecast that the global PC market is shrinking. According to an analysis of experts with the Ministry of the Electronics Industry, the institutional demand for PCs will substantially increase with the implementation of the national economy information management system.展开更多
Similar to the cross-border flow of commodities through trade,the global allocation of capital and the globalization of manufacturing are also subject to important domestic political influence.By increasing demand for...Similar to the cross-border flow of commodities through trade,the global allocation of capital and the globalization of manufacturing are also subject to important domestic political influence.By increasing demand for production factors and supply of products,the inflow of IFDI will increase competitive pressures facing manufacturers in the host country.This effect is similar to the import of goods.As such,in the face of external competitive pressures,the host country's manufacturers will oppose the inflow of foreign capital like they oppose the import of commodities unless restrictive measures are introduced.However,as revealed by the analysis on the attitudes of US semiconductor,renewable energy and steel manufacturers toward IFDI since the 1980 s,whether or not the manufacturers of a host country will call for restrictive or discriminatory policy against IFDI is largely influenced by the magnitude of their commercial interests in the source country of investment.A major factor of such influence is the potential reaction of the source country.Specifically,when a manufacturer has significant commercial interests in the source country of investment,this manufacturer is more likely to have an open policy preference toward direct investment from this country,and vice versa.展开更多
For more than half a centurymanufacturers in search of independentrepresentatives to sell their products innew markets and to establishrelationships with prospective customershave relied upon the services of theManufa...For more than half a centurymanufacturers in search of independentrepresentatives to sell their products innew markets and to establishrelationships with prospective customershave relied upon the services of theManufacturers’ Agents NationalAssociation (MANA).展开更多
Since the year 2006, having been trained in EHV power grid construction, indigenous manufacturing companies have gradually become full-fledged. With the advancement of the UHV program, they become more confident. Amon...Since the year 2006, having been trained in EHV power grid construction, indigenous manufacturing companies have gradually become full-fledged. With the advancement of the UHV program, they become more confident. Among these companies, there are Xi'an Shiky High Voltage Electric Co., Ltd.(Shiky) of China XD Group(XD), a mega state-owned enterprise, Tebian Electric Apparatus Stock Co., Ltd. (TBEA), a stock company, as well as Baoding Tianwei Baobian Electric Co., Ltd. (TWBB), a dark horse among private sectors. Moreover, Shanghai Sieyuan Electric Co., Ltd.(Sieyuan), which is especially mentionable, has attracted more attention in the industry for its outstanding and rapidly rising market performance.展开更多
According to Q2 Report on China’s Wearable Device Market,China’s wearable devices in Q2 2016 saw an output of 9.54 million units,up 13.2%month-on-month and 81.4%yearon-year.The basic wearable devices representing by...According to Q2 Report on China’s Wearable Device Market,China’s wearable devices in Q2 2016 saw an output of 9.54 million units,up 13.2%month-on-month and 81.4%yearon-year.The basic wearable devices representing by wristband,children watch and smart shoes increased by92.1%year-on-year and the smart wearable devices represented by smart watch increased by 3.4%year-on-year.'Unlike the overseas展开更多
Shanghai, China. August 29, 2008-Cutting edge fashion and design, advanced textile technology and innovative industry partnerships were brought together in Shanghai at the launch of XLA? Denim Fashion Show to introduc...Shanghai, China. August 29, 2008-Cutting edge fashion and design, advanced textile technology and innovative industry partnerships were brought together in Shanghai at the launch of XLA? Denim Fashion Show to introduce the next-generation XLA<sup>TM</sup> stretch fiber for denim application.展开更多
Garment manufacturers give utmost importance on quality of fabrics, cuts and design as they make a fashion statement. Manufacturers adjust their production cycles as per fashion oriented changes.
Developing Country Vaccine Industry represented by Developing Country Vaccine Manufacturer Network has a track record of manufacturing high quality vaccines.The timely and consistently supplies by DCVMN has led to sig...Developing Country Vaccine Industry represented by Developing Country Vaccine Manufacturer Network has a track record of manufacturing high quality vaccines.The timely and consistently supplies by DCVMN has led to significant progress in expanding the coverage of vaccine globally,resulting in the prevention of more than 2 million death annually.The contributions of industry to polio eradication,meningitis epidemic,pandemic influenza,MMR vaccination and DPTbased combination vaccines have created a significant impact on global health indicators[1].展开更多
Lightweight aluminum(Al)alloys have been widely used in frontier fields like aerospace and automotive industries,which attracts great interest in additive manufacturing(AM)to process high-value Al parts.As a mainstrea...Lightweight aluminum(Al)alloys have been widely used in frontier fields like aerospace and automotive industries,which attracts great interest in additive manufacturing(AM)to process high-value Al parts.As a mainstream AM technique,laser-directed energy deposition(LDED)shows good scalability to meet the requirements for large-format component manufacturing and repair.However,LDED Al alloys are highly challenging due to their inherent poor printability(e.g.low laser absorption,high oxidation sensitivity and cracking tendency).To further promote the development of LDED high-performance Al alloys,this review offers a deep understanding of the challenges and strategies to improve printability in LDED Al alloys.The porosity,cracking,distortion,inclusions,element evaporation and resultant inferior mechanical properties(worse than laser powder bed fusion)are the key challenges in LDED Al alloys.Processing parameter optimizations,in-situ alloy design,reinforcing particle addition and field assistance are the efficient approaches to improving the printability and performance of LDED Al alloys.The underlying correlations between processes,alloy innovation,characteristic microstructures,and achievable performances in LDED Al alloys are discussed.The benchmark mechanical properties and primary strengthening mechanism of LDED Al alloys are summarized.This review aims to provide a critical and in-depth evaluation of current progress in LDED Al alloys.Future opportunities and perspectives in LDED high-performance Al alloys are also outlined.展开更多
Melt extrusion-based additive manufacturing(ME-AM)is a promising technique to fabricate porous scaffolds for tissue engi-neering applications.However,most synthetic semicrystalline polymers do not possess the intrinsi...Melt extrusion-based additive manufacturing(ME-AM)is a promising technique to fabricate porous scaffolds for tissue engi-neering applications.However,most synthetic semicrystalline polymers do not possess the intrinsic biological activity required to control cell fate.Grafting of biomolecules on polymeric surfaces of AM scaffolds enhances the bioactivity of a construct;however,there are limited strategies available to control the surface density.Here,we report a strategy to tune the surface density of bioactive groups by blending a low molecular weight poly(ε-caprolactone)5k(PCL5k)containing orthogonally reactive azide groups with an unfunctionalized high molecular weight PCL75k at different ratios.Stable porous three-dimensional(3D)scaf-folds were then fabricated using a high weight percentage(75 wt.%)of the low molecular weight PCL 5k.As a proof-of-concept test,we prepared films of three different mass ratios of low and high molecular weight polymers with a thermopress and reacted with an alkynated fluorescent model compound on the surface,yielding a density of 201-561 pmol/cm^(2).Subsequently,a bone morphogenetic protein 2(BMP-2)-derived peptide was grafted onto the films comprising different blend compositions,and the effect of peptide surface density on the osteogenic differentiation of human mesenchymal stromal cells(hMSCs)was assessed.After two weeks of culturing in a basic medium,cells expressed higher levels of BMP receptor II(BMPRII)on films with the conjugated peptide.In addition,we found that alkaline phosphatase activity was only significantly enhanced on films contain-ing the highest peptide density(i.e.,561 pmol/cm^(2)),indicating the importance of the surface density.Taken together,these results emphasize that the density of surface peptides on cell differentiation must be considered at the cell-material interface.Moreover,we have presented a viable strategy for ME-AM community that desires to tune the bulk and surface functionality via blending of(modified)polymers.Furthermore,the use of alkyne-azide“click”chemistry enables spatial control over bioconjugation of many tissue-specific moieties,making this approach a versatile strategy for tissue engineering applications.展开更多
China removed fertilizer manufacturing subsidies from 2015 to 2018 to bolster market-oriented reforms and foster environmentally sustainable practices.However,the impact of this policy reform on food security and the ...China removed fertilizer manufacturing subsidies from 2015 to 2018 to bolster market-oriented reforms and foster environmentally sustainable practices.However,the impact of this policy reform on food security and the environment remains inadequately evaluated.Moreover,although green and low-carbon technologies offer environmental advantages,their widespread adoption is hindered by prohibitively high costs.This study analyzes the impact of removing fertilizer manufacturing subsidies and explores the potential feasibility of redirecting fertilizer manufacturing subsidies to invest in the diffusion of these technologies.Utilizing the China Agricultural University Agri-food Systems model,we analyzed the potential for achieving mutually beneficial outcomes regarding food security and environmental sustainability.The findings indicate that removing fertilizer manufacturing subsidies has reduced greenhouse gas(GHG)emissions from agricultural activities by 3.88 million metric tons,with minimal impact on food production.Redirecting fertilizer manufacturing subsidies to invest in green and low-carbon technologies,including slow and controlled-release fertilizer,organic-inorganic compound fertilizers,and machine deep placement of fertilizer,emerges as a strategy to concurrently curtail GHG emissions,ensure food security,and secure robust economic returns.Finally,we propose a comprehensive set of government interventions,including subsidies,field guidance,and improved extension systems,to promote the widespread adoption of these technologies.展开更多
Nd-Fe-B permanent magnets play a crucial role in energy conversion and electronic devices.The essential magnetic properties of Nd-Fe-B magnets,particularly coercivity and remanent magnetization,are significantly infue...Nd-Fe-B permanent magnets play a crucial role in energy conversion and electronic devices.The essential magnetic properties of Nd-Fe-B magnets,particularly coercivity and remanent magnetization,are significantly infuenced by the phase characteristics and microstructure.In this work,Nd-Fe-B magnets were manufactured using vacuum induction melting(VIM),laser directed energy deposition(LDED)and laser powder bed fusion(LPBF)technologies.Themicrostructure evolution and phase selection of Nd-Fe-B magnets were then clarified in detail.The results indicated that the solidification velocity(V)and cooling rate(R)are key factors in the phase selection.In terms of the VIM-casting Nd-Fe-B magnet,a large volume fraction of theα-Fe soft magnetic phase(39.7 vol.%)and Nd2Fe17Bxmetastable phase(34.7 vol.%)areformed due to the low R(2.3×10-1?C s-1),whereas only a minor fraction of the Nd2Fe14B hard magnetic phase(5.15 vol.%)is presented.For the LDED-processed Nd-Fe-B deposit,although the Nd2Fe14B hard magnetic phase also had a low value(3.4 vol.%)as the values of V(<10-2m s-1)and R(5.06×103?C s-1)increased,part of theα-Fe soft magnetic phase(31.7vol.%)is suppressed,and a higher volume of Nd2Fe17Bxmetastable phases(47.5 vol.%)areformed.As a result,both the VIM-casting and LDED-processed Nd-Fe-B deposits exhibited poor magnetic properties.In contrast,employing the high values of V(>10-2m s-1)and R(1.45×106?C s-1)in the LPBF process resulted in the substantial formation of the Nd2Fe14B hard magnetic phase(55.8 vol.%)directly from the liquid,while theα-Fe soft magnetic phase and Nd2Fe17Bxmetastable phase precipitation are suppressed in the LPBF-processed Nd-Fe-B magnet.Additionally,crystallographic texture analysis reveals that the LPBF-processedNd-Fe-B magnets exhibit isotropic magnetic characteristics.Consequently,the LPBF-processed Nd-Fe-B deposit,exhibiting a coercivity of 656 k A m-1,remanence of 0.79 T and maximum energy product of 71.5 k J m-3,achieved an acceptable magnetic performance,comparable to other additive manufacturing processed Nd-Fe-B magnets from MQP(Nd-lean)Nd-Fe-Bpowder.展开更多
Multi-material laser-based powder bed fusion (PBF-LB) allows manufacturing of parts with 3-dimensional gradient and additional functionality in a single step. This research focuses on the combination of thermally-cond...Multi-material laser-based powder bed fusion (PBF-LB) allows manufacturing of parts with 3-dimensional gradient and additional functionality in a single step. This research focuses on the combination of thermally-conductive CuCr1Zr with hard M300 tool steel.Two interface configurations of M300 on CuCr1Zr and CuCr1Zr on M300 were investigated. Ultra-fine grains form at the interface due to the low mutual solubility of Cu and steel. The material mixing zone size is dependent on the configurations and tunable in the range of0.1–0.3 mm by introducing a separate set of parameters for the interface layers. Microcracks and pores mainly occur in the transition zone.Regardless of these defects, the thermal diffusivity of bimetallic parts with 50vol% of CuCr1Zr significantly increases by 70%–150%compared to pure M300. The thermal diffusivity of CuCr1Zr and the hardness of M300 steel can be enhanced simultaneously by applying the aging heat treatment.展开更多
Bacterial colonization of orthopedic implants is one of the leading causes of failure and clinical complexities for load-bearing metallic implants. Topical or systemic administration of antibiotics may not offer the m...Bacterial colonization of orthopedic implants is one of the leading causes of failure and clinical complexities for load-bearing metallic implants. Topical or systemic administration of antibiotics may not offer the most efficient defense against colonization, especially in the case of secondary infection, leading to surgical removal of implants and in some cases even limbs. In this study, laser powder bed fusion was implemented to fabricate Ti3Al2V alloy by a 1:1 weight mixture of CpTi and Ti6Al4V powders. Ti-Tantalum(Ta)–Copper(Cu) alloys were further analyzed by the addition of Ta and Cu into the Ti3Al2V custom alloy. The biological,mechanical, and tribo-biocorrosion properties of Ti3Al2V alloy were evaluated. A 10 wt.% Ta(10Ta) and 3 wt.% Cu(3Cu) were added to the Ti3Al2V alloy to enhance biocompatibility and impart inherent bacterial resistance. Additively manufactured implants were investigated for resistance against Pseudomonas aeruginosa and Staphylococcus aureus strains of bacteria for up to 48 h. A 3 wt.% Cu addition to Ti3Al2V displayed improved antibacterial efficacy, i.e.78%–86% with respect to CpTi. Mechanical properties for Ti3Al2V–10Ta–3Cu alloy were evaluated, demonstrating excellent fatigue resistance, exceptional shear strength, and improved tribological and tribo-biocorrosion characteristics when compared to Ti6Al4V. In vivo studies using a rat distal femur model revealed improved early-stage osseointegration for alloys with10 wt.% Ta addition compared to CpTi and Ti6Al4V. The 3 wt.% Cu-added compositions displayed biocompatibility and no adverse infammatory response in vivo. Our results establish the Ti3Al2V–10Ta–3Cu alloy’s synergistic effect on improving both in vivo biocompatibility and microbial resistance for the next generation of load-bearing metallic implants.展开更多
Mg-alloys have gained considerable attention in recent years for their outstanding properties such as lightweight,high specific strength,and corrosion resistance,making them attractive for applications in medical,aero...Mg-alloys have gained considerable attention in recent years for their outstanding properties such as lightweight,high specific strength,and corrosion resistance,making them attractive for applications in medical,aerospace,automotive,and other transport industries.However,their widespread application is hindered by their low formability at room temperature due to limited slip systems.Cast Mg-alloys have low mechanical properties due to the presence of casting defects such as porosity and anisotropy in addition to the high scrap.While casting methods benefit from established process optimization techniques for these problems,additive manufacturing methods are increasingly replacing casting methods in Mg alloys as they provide more precise control over the microstructure and allow specific grain orientations,potentially enabling easier optimization of anisotropy properties in certain applications.Although metal additive manufacturing(MAM)technology also results in some manufacturing defects such as inhomogeneous microstructural evolution and porosity and additively manufactured Mg alloy parts exhibit lower properties than the wrought parts,they in general exhibit superior properties than the cast counterparts.Thus,MAM is a promising technique to produce Mg alloy parts.Directed energy deposition processes,particularly wire arc directed energy deposition(WA-DED),have emerged as an advantageous additive manufacturing(AM)technique for metallic materials including magnesium alloys,offering advantages such as high deposition rates,improved material efficiency,and reduced production costs compared to subtractive processes.However,the inherent challenges associated with magnesium,such as its high reactivity and susceptibility to oxidation,pose unique hurdles in the application of this technology.This review paper delves into the progress made in the application of DED technology to Mg-alloys,its challenges,and prospects.Furthermore,the predominant imperfections,notably inhomogeneous microstructure evolution and porosity,observed in Mg-alloy components manufactured through DED are discussed.Additionally,the preventive measures implemented to counteract the formation of these defects are explored.展开更多
Metal matrix composites(MMCs)are frequently employed in various advanced industries due to their high modulus and strength,favorable wear and corrosion resistance,and other good properties at elevated temperatures.In ...Metal matrix composites(MMCs)are frequently employed in various advanced industries due to their high modulus and strength,favorable wear and corrosion resistance,and other good properties at elevated temperatures.In recent decades,additive manufacturing(AM)technology has garnered attention as a potential way for fabricating MMCs.This article provides a comprehensive review of recent endeavors and progress in AM of MMCs,encompassing available AM technologies,types of reinforcements,feedstock preparation,synthesis principles during the AM process,typical AM-produced MMCs,strengthening mechanisms,challenges,and future interests.Compared to conventionally manufactured MMCs,AM-produced MMCs exhibit more uniformly distributed reinforcements and refined microstructure,resulting in comparable or even better mechanical properties.In addition,AM technology can produce bulk MMCs with significantly low porosity and fabricate geometrically complex MMC components and MMC lattice structures.As reviewed,many AM-produced MMCs,such as Al matrix composites,Ti matrix composites,nickel matrix composites,Fe matrix composites,etc,have been successfully produced.The types and contents of reinforcements strongly influence the properties of AM-produced MMCs,the choice of AM technology,and the applied processing parameters.In these MMCs,four primary strengthening mechanisms have been identified:Hall–Petch strengthening,dislocation strengthening,load transfer strengthening,and Orowan strengthening.AM technologies offer advantages that enhance the properties of MMCs when compared with traditional fabrication methods.Despite the advantages above,further challenges of AM-produced MMCs are still faced,such as new methods and new technologies for investigating AM-produced MMCs,the intrinsic nature of MMCs coupled with AM technologies,and challenges in the AM processes.Therefore,the article concludes by discussing the challenges and future interests of AM of MMCs.展开更多
Machine tools,often referred to as the“mother machines”of the manufacturing industry,are crucial in developing smart manufacturing and are increasingly becoming more intelligent.Digital twin technology can promote m...Machine tools,often referred to as the“mother machines”of the manufacturing industry,are crucial in developing smart manufacturing and are increasingly becoming more intelligent.Digital twin technology can promote machine tool intelligence and has attracted considerable research interest.However,there is a lack of clear and systematic analyses on how the digital twin technology enables machine tool intelligence.Herein,digital twin modeling was identified as an enabling technology for machine tool intelligence based on a comparative study of the characteristics of machine tool intelligence and digital twin.The review then delves into state-of-the-art digital twin modelingenabled machine tool intelligence,examining it from the aspects of data-based modeling and mechanism-data dual-driven modeling.Additionally,it highlights three bottleneck issues facing the field.Considering these problems,the architecture of a digital twin machine tool(DTMT)is proposed,and three key technologies are expounded in detail:Data perception and fusion technology,mechanism-data-knowledge hybrid-driven digital twin modeling and virtual-real synchronization technology,and dynamic optimization and collaborative control technology for multilevel parameters.Finally,future research directions for the DTMT are discussed.This work can provide a foundation basis for the research and implementation of digital-twin modeling-enabled machine tool intelligence,making it significant for developing intelligent machine tools.展开更多
文摘UK manufacturers experienced a challenging start to 2024,with sales in the first quarter(Q1)down 10 per cent on the previous quarter,according to a report by Unleashed.However,year-on-year growth showed a modest increase of 2 per cent,reflecting the Bank of England’s assessment of weak growth in the manufacturing sector.
文摘One of the core competencies of a supermarket lies in its branding.With the continuous development of the market economy and the ongoing evolution of consumer demand,private brands have progressively emerged as significant contributors to supermarket growth.However,a pivotal developmental challenge for supermarkets is navigating the innovative decision-making process between private brands and designated manufacturers.This paper aims to investigate the innovative decisions between private brands and designated manufacturers,along with the relevant promotional strategies employed during entry into the United States market.
文摘The potential Chinese market is increasingly attracting the major PC producers of the world, against a background of a forecast that the global PC market is shrinking. According to an analysis of experts with the Ministry of the Electronics Industry, the institutional demand for PCs will substantially increase with the implementation of the national economy information management system.
文摘Similar to the cross-border flow of commodities through trade,the global allocation of capital and the globalization of manufacturing are also subject to important domestic political influence.By increasing demand for production factors and supply of products,the inflow of IFDI will increase competitive pressures facing manufacturers in the host country.This effect is similar to the import of goods.As such,in the face of external competitive pressures,the host country's manufacturers will oppose the inflow of foreign capital like they oppose the import of commodities unless restrictive measures are introduced.However,as revealed by the analysis on the attitudes of US semiconductor,renewable energy and steel manufacturers toward IFDI since the 1980 s,whether or not the manufacturers of a host country will call for restrictive or discriminatory policy against IFDI is largely influenced by the magnitude of their commercial interests in the source country of investment.A major factor of such influence is the potential reaction of the source country.Specifically,when a manufacturer has significant commercial interests in the source country of investment,this manufacturer is more likely to have an open policy preference toward direct investment from this country,and vice versa.
文摘For more than half a centurymanufacturers in search of independentrepresentatives to sell their products innew markets and to establishrelationships with prospective customershave relied upon the services of theManufacturers’ Agents NationalAssociation (MANA).
文摘Since the year 2006, having been trained in EHV power grid construction, indigenous manufacturing companies have gradually become full-fledged. With the advancement of the UHV program, they become more confident. Among these companies, there are Xi'an Shiky High Voltage Electric Co., Ltd.(Shiky) of China XD Group(XD), a mega state-owned enterprise, Tebian Electric Apparatus Stock Co., Ltd. (TBEA), a stock company, as well as Baoding Tianwei Baobian Electric Co., Ltd. (TWBB), a dark horse among private sectors. Moreover, Shanghai Sieyuan Electric Co., Ltd.(Sieyuan), which is especially mentionable, has attracted more attention in the industry for its outstanding and rapidly rising market performance.
文摘According to Q2 Report on China’s Wearable Device Market,China’s wearable devices in Q2 2016 saw an output of 9.54 million units,up 13.2%month-on-month and 81.4%yearon-year.The basic wearable devices representing by wristband,children watch and smart shoes increased by92.1%year-on-year and the smart wearable devices represented by smart watch increased by 3.4%year-on-year.'Unlike the overseas
文摘Shanghai, China. August 29, 2008-Cutting edge fashion and design, advanced textile technology and innovative industry partnerships were brought together in Shanghai at the launch of XLA? Denim Fashion Show to introduce the next-generation XLA<sup>TM</sup> stretch fiber for denim application.
文摘Garment manufacturers give utmost importance on quality of fabrics, cuts and design as they make a fashion statement. Manufacturers adjust their production cycles as per fashion oriented changes.
文摘Developing Country Vaccine Industry represented by Developing Country Vaccine Manufacturer Network has a track record of manufacturing high quality vaccines.The timely and consistently supplies by DCVMN has led to significant progress in expanding the coverage of vaccine globally,resulting in the prevention of more than 2 million death annually.The contributions of industry to polio eradication,meningitis epidemic,pandemic influenza,MMR vaccination and DPTbased combination vaccines have created a significant impact on global health indicators[1].
基金supported by the 2022 MTC Young Individual Research Grants(Grant No.M22K3c0097)the Singapore Research,Innovation and Enterprise(RIE)2025 PlanSingapore Aerospace Programme Cycle 16(Grant No.M2215a0073)。
文摘Lightweight aluminum(Al)alloys have been widely used in frontier fields like aerospace and automotive industries,which attracts great interest in additive manufacturing(AM)to process high-value Al parts.As a mainstream AM technique,laser-directed energy deposition(LDED)shows good scalability to meet the requirements for large-format component manufacturing and repair.However,LDED Al alloys are highly challenging due to their inherent poor printability(e.g.low laser absorption,high oxidation sensitivity and cracking tendency).To further promote the development of LDED high-performance Al alloys,this review offers a deep understanding of the challenges and strategies to improve printability in LDED Al alloys.The porosity,cracking,distortion,inclusions,element evaporation and resultant inferior mechanical properties(worse than laser powder bed fusion)are the key challenges in LDED Al alloys.Processing parameter optimizations,in-situ alloy design,reinforcing particle addition and field assistance are the efficient approaches to improving the printability and performance of LDED Al alloys.The underlying correlations between processes,alloy innovation,characteristic microstructures,and achievable performances in LDED Al alloys are discussed.The benchmark mechanical properties and primary strengthening mechanism of LDED Al alloys are summarized.This review aims to provide a critical and in-depth evaluation of current progress in LDED Al alloys.Future opportunities and perspectives in LDED high-performance Al alloys are also outlined.
基金the European Research Council starting grant “Cell Hybridge” for financial support under the Horizon2020 framework program (Grant#637308)the Province of Limburg for support and funding
文摘Melt extrusion-based additive manufacturing(ME-AM)is a promising technique to fabricate porous scaffolds for tissue engi-neering applications.However,most synthetic semicrystalline polymers do not possess the intrinsic biological activity required to control cell fate.Grafting of biomolecules on polymeric surfaces of AM scaffolds enhances the bioactivity of a construct;however,there are limited strategies available to control the surface density.Here,we report a strategy to tune the surface density of bioactive groups by blending a low molecular weight poly(ε-caprolactone)5k(PCL5k)containing orthogonally reactive azide groups with an unfunctionalized high molecular weight PCL75k at different ratios.Stable porous three-dimensional(3D)scaf-folds were then fabricated using a high weight percentage(75 wt.%)of the low molecular weight PCL 5k.As a proof-of-concept test,we prepared films of three different mass ratios of low and high molecular weight polymers with a thermopress and reacted with an alkynated fluorescent model compound on the surface,yielding a density of 201-561 pmol/cm^(2).Subsequently,a bone morphogenetic protein 2(BMP-2)-derived peptide was grafted onto the films comprising different blend compositions,and the effect of peptide surface density on the osteogenic differentiation of human mesenchymal stromal cells(hMSCs)was assessed.After two weeks of culturing in a basic medium,cells expressed higher levels of BMP receptor II(BMPRII)on films with the conjugated peptide.In addition,we found that alkaline phosphatase activity was only significantly enhanced on films contain-ing the highest peptide density(i.e.,561 pmol/cm^(2)),indicating the importance of the surface density.Taken together,these results emphasize that the density of surface peptides on cell differentiation must be considered at the cell-material interface.Moreover,we have presented a viable strategy for ME-AM community that desires to tune the bulk and surface functionality via blending of(modified)polymers.Furthermore,the use of alkyne-azide“click”chemistry enables spatial control over bioconjugation of many tissue-specific moieties,making this approach a versatile strategy for tissue engineering applications.
基金The authors acknowledge the financial support received from the National Natural Science Foundation of China(72061147002).
文摘China removed fertilizer manufacturing subsidies from 2015 to 2018 to bolster market-oriented reforms and foster environmentally sustainable practices.However,the impact of this policy reform on food security and the environment remains inadequately evaluated.Moreover,although green and low-carbon technologies offer environmental advantages,their widespread adoption is hindered by prohibitively high costs.This study analyzes the impact of removing fertilizer manufacturing subsidies and explores the potential feasibility of redirecting fertilizer manufacturing subsidies to invest in the diffusion of these technologies.Utilizing the China Agricultural University Agri-food Systems model,we analyzed the potential for achieving mutually beneficial outcomes regarding food security and environmental sustainability.The findings indicate that removing fertilizer manufacturing subsidies has reduced greenhouse gas(GHG)emissions from agricultural activities by 3.88 million metric tons,with minimal impact on food production.Redirecting fertilizer manufacturing subsidies to invest in green and low-carbon technologies,including slow and controlled-release fertilizer,organic-inorganic compound fertilizers,and machine deep placement of fertilizer,emerges as a strategy to concurrently curtail GHG emissions,ensure food security,and secure robust economic returns.Finally,we propose a comprehensive set of government interventions,including subsidies,field guidance,and improved extension systems,to promote the widespread adoption of these technologies.
基金supported by the National Key R&D Program of China(Grant No.2022YFB4600300)the National Natural Science Foundation of China(No.U22A20189,52175364)the China Scholarship Council(Grant No.202206290134)。
文摘Nd-Fe-B permanent magnets play a crucial role in energy conversion and electronic devices.The essential magnetic properties of Nd-Fe-B magnets,particularly coercivity and remanent magnetization,are significantly infuenced by the phase characteristics and microstructure.In this work,Nd-Fe-B magnets were manufactured using vacuum induction melting(VIM),laser directed energy deposition(LDED)and laser powder bed fusion(LPBF)technologies.Themicrostructure evolution and phase selection of Nd-Fe-B magnets were then clarified in detail.The results indicated that the solidification velocity(V)and cooling rate(R)are key factors in the phase selection.In terms of the VIM-casting Nd-Fe-B magnet,a large volume fraction of theα-Fe soft magnetic phase(39.7 vol.%)and Nd2Fe17Bxmetastable phase(34.7 vol.%)areformed due to the low R(2.3×10-1?C s-1),whereas only a minor fraction of the Nd2Fe14B hard magnetic phase(5.15 vol.%)is presented.For the LDED-processed Nd-Fe-B deposit,although the Nd2Fe14B hard magnetic phase also had a low value(3.4 vol.%)as the values of V(<10-2m s-1)and R(5.06×103?C s-1)increased,part of theα-Fe soft magnetic phase(31.7vol.%)is suppressed,and a higher volume of Nd2Fe17Bxmetastable phases(47.5 vol.%)areformed.As a result,both the VIM-casting and LDED-processed Nd-Fe-B deposits exhibited poor magnetic properties.In contrast,employing the high values of V(>10-2m s-1)and R(1.45×106?C s-1)in the LPBF process resulted in the substantial formation of the Nd2Fe14B hard magnetic phase(55.8 vol.%)directly from the liquid,while theα-Fe soft magnetic phase and Nd2Fe17Bxmetastable phase precipitation are suppressed in the LPBF-processed Nd-Fe-B magnet.Additionally,crystallographic texture analysis reveals that the LPBF-processedNd-Fe-B magnets exhibit isotropic magnetic characteristics.Consequently,the LPBF-processed Nd-Fe-B deposit,exhibiting a coercivity of 656 k A m-1,remanence of 0.79 T and maximum energy product of 71.5 k J m-3,achieved an acceptable magnetic performance,comparable to other additive manufacturing processed Nd-Fe-B magnets from MQP(Nd-lean)Nd-Fe-Bpowder.
基金supported by VTT Technical Research Centre of Finland,Aalto University,Aerosint SA,and partially from European Union Horizon 2020 (No.768775)。
文摘Multi-material laser-based powder bed fusion (PBF-LB) allows manufacturing of parts with 3-dimensional gradient and additional functionality in a single step. This research focuses on the combination of thermally-conductive CuCr1Zr with hard M300 tool steel.Two interface configurations of M300 on CuCr1Zr and CuCr1Zr on M300 were investigated. Ultra-fine grains form at the interface due to the low mutual solubility of Cu and steel. The material mixing zone size is dependent on the configurations and tunable in the range of0.1–0.3 mm by introducing a separate set of parameters for the interface layers. Microcracks and pores mainly occur in the transition zone.Regardless of these defects, the thermal diffusivity of bimetallic parts with 50vol% of CuCr1Zr significantly increases by 70%–150%compared to pure M300. The thermal diffusivity of CuCr1Zr and the hardness of M300 steel can be enhanced simultaneously by applying the aging heat treatment.
基金supported by the National Institute of Arthritis and Musculoskeletal and Skin Diseases of the National Institutes of Health under Award Numbers R01 AR067306 and R01 AR078241。
文摘Bacterial colonization of orthopedic implants is one of the leading causes of failure and clinical complexities for load-bearing metallic implants. Topical or systemic administration of antibiotics may not offer the most efficient defense against colonization, especially in the case of secondary infection, leading to surgical removal of implants and in some cases even limbs. In this study, laser powder bed fusion was implemented to fabricate Ti3Al2V alloy by a 1:1 weight mixture of CpTi and Ti6Al4V powders. Ti-Tantalum(Ta)–Copper(Cu) alloys were further analyzed by the addition of Ta and Cu into the Ti3Al2V custom alloy. The biological,mechanical, and tribo-biocorrosion properties of Ti3Al2V alloy were evaluated. A 10 wt.% Ta(10Ta) and 3 wt.% Cu(3Cu) were added to the Ti3Al2V alloy to enhance biocompatibility and impart inherent bacterial resistance. Additively manufactured implants were investigated for resistance against Pseudomonas aeruginosa and Staphylococcus aureus strains of bacteria for up to 48 h. A 3 wt.% Cu addition to Ti3Al2V displayed improved antibacterial efficacy, i.e.78%–86% with respect to CpTi. Mechanical properties for Ti3Al2V–10Ta–3Cu alloy were evaluated, demonstrating excellent fatigue resistance, exceptional shear strength, and improved tribological and tribo-biocorrosion characteristics when compared to Ti6Al4V. In vivo studies using a rat distal femur model revealed improved early-stage osseointegration for alloys with10 wt.% Ta addition compared to CpTi and Ti6Al4V. The 3 wt.% Cu-added compositions displayed biocompatibility and no adverse infammatory response in vivo. Our results establish the Ti3Al2V–10Ta–3Cu alloy’s synergistic effect on improving both in vivo biocompatibility and microbial resistance for the next generation of load-bearing metallic implants.
文摘Mg-alloys have gained considerable attention in recent years for their outstanding properties such as lightweight,high specific strength,and corrosion resistance,making them attractive for applications in medical,aerospace,automotive,and other transport industries.However,their widespread application is hindered by their low formability at room temperature due to limited slip systems.Cast Mg-alloys have low mechanical properties due to the presence of casting defects such as porosity and anisotropy in addition to the high scrap.While casting methods benefit from established process optimization techniques for these problems,additive manufacturing methods are increasingly replacing casting methods in Mg alloys as they provide more precise control over the microstructure and allow specific grain orientations,potentially enabling easier optimization of anisotropy properties in certain applications.Although metal additive manufacturing(MAM)technology also results in some manufacturing defects such as inhomogeneous microstructural evolution and porosity and additively manufactured Mg alloy parts exhibit lower properties than the wrought parts,they in general exhibit superior properties than the cast counterparts.Thus,MAM is a promising technique to produce Mg alloy parts.Directed energy deposition processes,particularly wire arc directed energy deposition(WA-DED),have emerged as an advantageous additive manufacturing(AM)technique for metallic materials including magnesium alloys,offering advantages such as high deposition rates,improved material efficiency,and reduced production costs compared to subtractive processes.However,the inherent challenges associated with magnesium,such as its high reactivity and susceptibility to oxidation,pose unique hurdles in the application of this technology.This review paper delves into the progress made in the application of DED technology to Mg-alloys,its challenges,and prospects.Furthermore,the predominant imperfections,notably inhomogeneous microstructure evolution and porosity,observed in Mg-alloy components manufactured through DED are discussed.Additionally,the preventive measures implemented to counteract the formation of these defects are explored.
基金the financial support from the Australian Research Council through the Discovery Project(DP110101653 and DP130103592)Basic and Applied Basic Research Foundation of Guangdong Province,China(2022A1515140123).
文摘Metal matrix composites(MMCs)are frequently employed in various advanced industries due to their high modulus and strength,favorable wear and corrosion resistance,and other good properties at elevated temperatures.In recent decades,additive manufacturing(AM)technology has garnered attention as a potential way for fabricating MMCs.This article provides a comprehensive review of recent endeavors and progress in AM of MMCs,encompassing available AM technologies,types of reinforcements,feedstock preparation,synthesis principles during the AM process,typical AM-produced MMCs,strengthening mechanisms,challenges,and future interests.Compared to conventionally manufactured MMCs,AM-produced MMCs exhibit more uniformly distributed reinforcements and refined microstructure,resulting in comparable or even better mechanical properties.In addition,AM technology can produce bulk MMCs with significantly low porosity and fabricate geometrically complex MMC components and MMC lattice structures.As reviewed,many AM-produced MMCs,such as Al matrix composites,Ti matrix composites,nickel matrix composites,Fe matrix composites,etc,have been successfully produced.The types and contents of reinforcements strongly influence the properties of AM-produced MMCs,the choice of AM technology,and the applied processing parameters.In these MMCs,four primary strengthening mechanisms have been identified:Hall–Petch strengthening,dislocation strengthening,load transfer strengthening,and Orowan strengthening.AM technologies offer advantages that enhance the properties of MMCs when compared with traditional fabrication methods.Despite the advantages above,further challenges of AM-produced MMCs are still faced,such as new methods and new technologies for investigating AM-produced MMCs,the intrinsic nature of MMCs coupled with AM technologies,and challenges in the AM processes.Therefore,the article concludes by discussing the challenges and future interests of AM of MMCs.
基金Supported by Tianjin Municipal University Science and Technology Development Foundation of China(Grant No.2021KJ176).
文摘Machine tools,often referred to as the“mother machines”of the manufacturing industry,are crucial in developing smart manufacturing and are increasingly becoming more intelligent.Digital twin technology can promote machine tool intelligence and has attracted considerable research interest.However,there is a lack of clear and systematic analyses on how the digital twin technology enables machine tool intelligence.Herein,digital twin modeling was identified as an enabling technology for machine tool intelligence based on a comparative study of the characteristics of machine tool intelligence and digital twin.The review then delves into state-of-the-art digital twin modelingenabled machine tool intelligence,examining it from the aspects of data-based modeling and mechanism-data dual-driven modeling.Additionally,it highlights three bottleneck issues facing the field.Considering these problems,the architecture of a digital twin machine tool(DTMT)is proposed,and three key technologies are expounded in detail:Data perception and fusion technology,mechanism-data-knowledge hybrid-driven digital twin modeling and virtual-real synchronization technology,and dynamic optimization and collaborative control technology for multilevel parameters.Finally,future research directions for the DTMT are discussed.This work can provide a foundation basis for the research and implementation of digital-twin modeling-enabled machine tool intelligence,making it significant for developing intelligent machine tools.
