Medical knowledge graphs(MKGs)are the basis for intelligent health care,and they have been in use in a variety of intelligent medical applications.Thus,understanding the research and application development of MKGs wi...Medical knowledge graphs(MKGs)are the basis for intelligent health care,and they have been in use in a variety of intelligent medical applications.Thus,understanding the research and application development of MKGs will be crucial for future relevant research in the biomedical field.To this end,we offer an in-depth review of MKG in this work.Our research begins with the examination of four types of medical information sources,knowledge graph creation methodologies,and six major themes for MKG development.Furthermore,three popular models of reasoning from the viewpoint of knowledge reasoning are discussed.A reasoning implementation path(RIP)is proposed as a means of expressing the reasoning procedures for MKG.In addition,we explore intelligent medical applications based on RIP and MKG and classify them into nine major types.Finally,we summarize the current state of MKG research based on more than 130 publications and future challenges and opportunities.展开更多
The research on graph pattern matching(GPM) has attracted a lot of attention. However, most of the research has focused on complex networks, and there are few researches on GPM in the medical field. Hence, with GPM th...The research on graph pattern matching(GPM) has attracted a lot of attention. However, most of the research has focused on complex networks, and there are few researches on GPM in the medical field. Hence, with GPM this paper is to make a breast cancer-oriented diagnosis before the surgery. Technically, this paper has firstly made a new definition of GPM, aiming to explore the GPM in the medical field, especially in Medical Knowledge Graphs(MKGs). Then, in the specific matching process, this paper introduces fuzzy calculation, and proposes a multi-threaded bidirectional routing exploration(M-TBRE) algorithm based on depth first search and a two-way routing matching algorithm based on multi-threading. In addition, fuzzy constraints are introduced in the M-TBRE algorithm, which leads to the Fuzzy-M-TBRE algorithm. The experimental results on the two datasets show that compared with existing algorithms, our proposed algorithm is more efficient and effective.展开更多
基金supported in part by the National Key Research and Development Program of China(No.2021YFF1201200)the National Natural Science Foundation of China(No.62006251)the Science and Technology Innovation Program of Hunan Province(No.2021RC4008).
文摘Medical knowledge graphs(MKGs)are the basis for intelligent health care,and they have been in use in a variety of intelligent medical applications.Thus,understanding the research and application development of MKGs will be crucial for future relevant research in the biomedical field.To this end,we offer an in-depth review of MKG in this work.Our research begins with the examination of four types of medical information sources,knowledge graph creation methodologies,and six major themes for MKG development.Furthermore,three popular models of reasoning from the viewpoint of knowledge reasoning are discussed.A reasoning implementation path(RIP)is proposed as a means of expressing the reasoning procedures for MKG.In addition,we explore intelligent medical applications based on RIP and MKG and classify them into nine major types.Finally,we summarize the current state of MKG research based on more than 130 publications and future challenges and opportunities.
基金supported by the National Natural Science Foundation of China under grants 62076087&61906059the Program for Changjiang Scholars and Innovative Research Team in University(PCSIRT)of the Ministry of Education of China under grant IRT17R32
文摘The research on graph pattern matching(GPM) has attracted a lot of attention. However, most of the research has focused on complex networks, and there are few researches on GPM in the medical field. Hence, with GPM this paper is to make a breast cancer-oriented diagnosis before the surgery. Technically, this paper has firstly made a new definition of GPM, aiming to explore the GPM in the medical field, especially in Medical Knowledge Graphs(MKGs). Then, in the specific matching process, this paper introduces fuzzy calculation, and proposes a multi-threaded bidirectional routing exploration(M-TBRE) algorithm based on depth first search and a two-way routing matching algorithm based on multi-threading. In addition, fuzzy constraints are introduced in the M-TBRE algorithm, which leads to the Fuzzy-M-TBRE algorithm. The experimental results on the two datasets show that compared with existing algorithms, our proposed algorithm is more efficient and effective.
