A 68-years old woman presented with ahistory of recurrent fever of 38-39°ac-companied by chills and weakness over the past month.Her physical examination was unremarkable except for an audible 3/6 ejection murmur...A 68-years old woman presented with ahistory of recurrent fever of 38-39°ac-companied by chills and weakness over the past month.Her physical examination was unremarkable except for an audible 3/6 ejection murmur at the 2nd right intercostal space.Her vital signs were normal with no fever at presentation.Laboratory tests showed elevated white blood count of 11,800cells/mm3 with a remarkable neutrophilia and elevated C-reactive protein of 14 mg/dL.Blood glucose,renal and liver function tests were all normal.展开更多
Face forgery detection is drawing ever-increasing attention in the academic community owing to security concerns.Despite the considerable progress in existing methods,we note that:Previous works overlooked finegrain f...Face forgery detection is drawing ever-increasing attention in the academic community owing to security concerns.Despite the considerable progress in existing methods,we note that:Previous works overlooked finegrain forgery cues with high transferability.Such cues positively impact the model’s accuracy and generalizability.Moreover,single-modality often causes overfitting of the model,and Red-Green-Blue(RGB)modal-only is not conducive to extracting the more detailed forgery traces.We propose a novel framework for fine-grain forgery cues mining with fusion modality to cope with these issues.First,we propose two functional modules to reveal and locate the deeper forged features.Our method locates deeper forgery cues through a dual-modality progressive fusion module and a noise adaptive enhancement module,which can excavate the association between dualmodal space and channels and enhance the learning of subtle noise features.A sensitive patch branch is introduced on this foundation to enhance the mining of subtle forgery traces under fusion modality.The experimental results demonstrate that our proposed framework can desirably explore the differences between authentic and forged images with supervised learning.Comprehensive evaluations of several mainstream datasets show that our method outperforms the state-of-the-art detection methods with remarkable detection ability and generalizability.展开更多
Nowadays,it is extremely urgent for the software engineering education to cultivate the knowledge and ability of database talents in the era of big data.To this end,this paper proposes a talent training teaching modal...Nowadays,it is extremely urgent for the software engineering education to cultivate the knowledge and ability of database talents in the era of big data.To this end,this paper proposes a talent training teaching modality that integrates knowledge,ability,practice,and innovation(KAPI)for Database System Course.The teaching modality contains three parts:top-level design,course learning process,and course assurance and evaluation.The top-level design sorts out the core knowledge of the course and determines a mixed online and offline teaching platform.The course learning process emphasizes the correspondence transformation relationship between core knowledge points and ability enhancement,and the course is practiced in the form of experimental projects to finally enhance students’innovation consciousness and ability.The assurance and evaluation of the course are based on the outcome-based education(OBE)orientation,which realizes the objective evaluation of students’learning process and final performance.The teaching results of the course in the past 2 years show that the KAPI-based teaching modality has achieved better results.Meanwhile,students are satisfied with the evaluation of the modality.The teaching modality in this paper helps to stimulate students’initiatives,and improve their knowledge vision and practical ability,and thus helps to cultivate innovative and high-quality engineering talents required by the emerging engineering education.展开更多
This paper aims at examing how modality values are realized in native and non-native English news reporting and comparing the values they each take.By analyzing,the writer hopes to contribute to the awareness of forei...This paper aims at examing how modality values are realized in native and non-native English news reporting and comparing the values they each take.By analyzing,the writer hopes to contribute to the awareness of foreign language learners in terms of the importance of modality values in news analysis and make readers benefit from their reading,writing.展开更多
Modality is used to express subjective judgment as well as the speaker’s opinions and attitudes.This paper aims to analyze the reporters’orientation reflected by linguistic modal expressions in English news reports ...Modality is used to express subjective judgment as well as the speaker’s opinions and attitudes.This paper aims to analyze the reporters’orientation reflected by linguistic modal expressions in English news reports from the perspective of Systemic-Functional Grammar,especially from the perspective of type,value,orientation and polarity.展开更多
Although the current standard treatment for hepatocellular carcinoma(HCC) with portal vein tumor thrombosis(PVTT) is sorafenib, many previous studies have established the need for a reliable local modality for PVTT co...Although the current standard treatment for hepatocellular carcinoma(HCC) with portal vein tumor thrombosis(PVTT) is sorafenib, many previous studies have established the need for a reliable local modality for PVTT control, which is a major cause of liver function deterioration and metastasis. Additionally, there is growing evidence for the prognostic significance of PVTT classification according to the location of tumor thrombosis. Favorable outcomes can be obtained by applying local modalities, including surgery or transarterial chemoembolization, especially in second-order or distal branch PVTT. Rapid control of PVTT could maintain or improve liver function and reduce intrahepatic as well as distant metastasis. Radiotherapy(RT) is one of the main locoregional treatment modalities in oncologic fields, but has rarely been used in HCC because of concerns regarding hepatic toxicity. However, with the development of advanced techniques, RT has been increasingly applied in HCC management. Randomized studies have yet to definitively prove the benefit of RT, but several comparative studies have justified the application of RT in HCC. The value of RT is especially noticeable in HCC with PVTT; several prospective and retrospective studies have reported favorable outcomes, including a 40% to 60% objective response rate and median overall survival of 15 mo to 20 mo in responders. In this review, we evaluate the role of RT as an alternative local modality in HCC with PVTT.展开更多
AIM: To compare the therapeutic effect and significances of multimodality treatment for hepatocellular carcinoma (HCC) with tumor thrombi in portal vein (PVTT). METHODS: HCC patients (n=147) with tumor thrombi in the ...AIM: To compare the therapeutic effect and significances of multimodality treatment for hepatocellular carcinoma (HCC) with tumor thrombi in portal vein (PVTT). METHODS: HCC patients (n=147) with tumor thrombi in the main portal vein or the first branch of portal vein were divided into four groups by the several therapeutic methods. There were conservative treatment group in 18 out of patients (group A); and hepatic artery ligation(HAL) and/or hepatic artery infusion (HAI) group in 18 patients (group B), in whom postoperative chemoembolization was done periodically; group of removal of HCC with PVTT in 79 (group C) and group of transcatheter hepatic arterial chemoembolization (TACE) or HAI and/or portal vein infusion (PVI) after operation in 32 (group D). RESULTS: The median survival period was 12 months in our series and the 1-,3-, and 5-year survival rates were 44.3%, 24.5% and 15.2%, respectively. The median survival times were 2, 5, 12 and 16 months in group A, B, C and D, respectively. The 1-, 3- and 5-year survival rates were 5.6%, 0% and 0% in group A; 22.2%, 5.6% and 0% in group B; 53.9%, 26.9% and 16.6% in group C; 79.3%, 38.9% and 26.8% in group D, respectively. Significant difference appeared in the survival rates among the groups (P 【 0.05). CONCLUSION: Hepatic resection with removal of tumor thrombi and HCC should increase the curative effects and be encouraged for the prolongation of life span and quality of life for HCC patients with PVTT, whereas the best therapeutic method for HCC with PVTT is with regional hepatic chemotherapy or chemoembolization after hepatic resection with removal of tumor thrombi.展开更多
There is a problem of unfairness in allocation of radio resources among heterogeneous mobile terminals in heterogeneous wireless networks. Low-capability mobile terminals (such as single-mode terminals) suffer high ca...There is a problem of unfairness in allocation of radio resources among heterogeneous mobile terminals in heterogeneous wireless networks. Low-capability mobile terminals (such as single-mode terminals) suffer high call blocking probability whereas high-capability mobile terminals (such as quad-mode terminals) experience very low call blocking probability, in the same heterogeneous wireless network. This paper proposes a Terminal-Modality-Based Joint Call Admission Control (TJCAC) algorithm to reduce this problem of unfairness. The proposed TJCAC algorithm makes call admission decisions based on mobile terminal modality (capability), network load, and radio access technology (RAT) terminal support index. The objectives of the proposed TJCAC algorithm are to reduce call blocking/dropping probability, and ensure fairness in allocation of radio resources among heterogeneous mobile terminals in heterogeneous networks. An analytical model is developed to evaluate the performance of the proposed TJCAC scheme in terms of call blocking/dropping probability in a heterogeneous wireless network. The performance of the proposed TJCAC algorithm is compared with that of other JCAC algorithms. Results show that the proposed algorithm reduces call blocking/dropping probability in the networks, and ensure fairness in allocation of radio resources among heterogeneous terminals.展开更多
The number of modes (also known as modality) of a kernel density estimator (KDE) draws lots of interests and is important in practice. In this paper, we develop an inference framework on the modality of a KDE under mu...The number of modes (also known as modality) of a kernel density estimator (KDE) draws lots of interests and is important in practice. In this paper, we develop an inference framework on the modality of a KDE under multivariate setting using Gaussian kernel. We applied the modal clustering method proposed by [1] for mode hunting. A test statistic and its asymptotic distribution are derived to assess the significance of each mode. The inference procedure is applied on both simulated and real data sets.展开更多
This study entails a first approach to epistemic modality in Woolf＇s essays. In particular, we will distinguish between assertive and non-assertive epistemic modality. Woolf uses assertive epistemic modality when tra...This study entails a first approach to epistemic modality in Woolf＇s essays. In particular, we will distinguish between assertive and non-assertive epistemic modality. Woolf uses assertive epistemic modality when transmitting her criticism to, sometimes, women＇s inferiority condition in history, revealing Woolf＇s more confident stance. These markers are different from those used in more ＂gentle＂ themes related to reviewing an author and her work. In this second case, non-assertive epistemic modality is more frequent. Being less harsh towards an author＇s surroundings and her literary production, Woolf＇s stance proves less self-assured. The corpus consists of 10 short essays. We also refer to her longer essays A Room of One＇s Own （1929） and Three Guineas 0938）. They were selected bearing in mind their subject-matter. Half of them deal with literature and women writers, their lives and works; the other half ones also have to do with women-related topics, but referring to their position in history and their difficulties to undertake, for example, a literary career. Some concluding remarks indicate the predominance of non-assertive epistemic modality in relation to an intersubjective reading of her texts. This reading favours the inclusion of her audience in her commentary about women writing.展开更多
The tenth BRICS Summit was held in Johannesburg,South Africa in 2018,which attracted attention from the whole world.Especially,it is of great importance to the BRICS nations,for it is the first ten years of BRICS,whic...The tenth BRICS Summit was held in Johannesburg,South Africa in 2018,which attracted attention from the whole world.Especially,it is of great importance to the BRICS nations,for it is the first ten years of BRICS,which marks its growth.Meanwhile,this year the Trump administration imposed more strict policies on protectionism.Particularly,the trade war between China and the United States is so intensive.China,as the core member of BRICS has great clout on BRICS,so the trade war between China and US also arouse a heat discussion among the BRICS nations.During the Summit,CGTN invited experts from the five BRICS nations to discuss related topics.Systemic Functional Linguistics,as one of the most influential branches of Linguistics,was firstly established by M.A.K.Halliday,and it has been greatly developed over the past decades.Interpersonal meaning is one of the three meta-functions,which focuses on how addressers use language to communicate,establish and maintain relationships with addressees,and express their opinions.Mood and modality are two basic resources to the realization of interpersonal meaning.Mood is used to represent the interaction of the language users,while modality reflects the utterers’attitudes and judgments.The paper discusses the three aspects of modality:modal operators,modal adjuncts and metaphors of modality.The paper applies the modality system to the analysis of the transcript of BRICS TALK.The author selects the experts’speeches on the trade war between China and US as the data.The research questions are as followed:(1)the characteristics of the modality resources appeared in their talks;(2)the BRICS nations attitudes and stance on trade war and America’s protectionism.展开更多
Imagine how many times your attention is distracted by the surrounding sounds or sights irrelevant to your work or study.To maintain concentrated,you have to control yourself intentionally,which is called"attenti...Imagine how many times your attention is distracted by the surrounding sounds or sights irrelevant to your work or study.To maintain concentrated,you have to control yourself intentionally,which is called"attentional control"or"cognitive control"in psychology.An interesting question arises:when we successfully direct our attention away from one visual distractor,can we be immune to another展开更多
Researchers in computer science and computer engineering devote a significant part of their efforts on communication and interaction between man and machine. Indeed, with the advent of multimedia and multimodal proces...Researchers in computer science and computer engineering devote a significant part of their efforts on communication and interaction between man and machine. Indeed, with the advent of multimedia and multimodal processing in real time, the computer is no longer considered only as a computational tool, but as a machine for processing, communication, collection and control. Many machines assist and support many activities in daily life. The main objective of this paper is to propose a new methodological solution by modeling an architecture that facilitates the work of multimodal system especially for a fission module. To realize such systems, we rely on ontology to integrate data semantically. Ontologies provide a structured vocabulary usedas support for data representation. This paper provides a better understanding of the fission system and multimodal interaction. We present our architecture and the description of the detection of optimal modalities. This is done by using an ontological model that contains different applicable scenarios and describes the environment where a multimodal system exists.展开更多
Business letter with friendly modality is an effective means to represent the best advantage of one's self and firm. The paper in vestigates modality in business letter according to Halliday's view on modality...Business letter with friendly modality is an effective means to represent the best advantage of one's self and firm. The paper in vestigates modality in business letter according to Halliday's view on modality. The modal devices mainly cover modal operator, modal ad junct, and modal cohesion. By means of binary approach modal logic is tentative divided into: perfective and imperfective; positive and neg ative; subjective and objective or explicit and implicit; high, median and low value. Modal devices or modal logic has formal and semantic level. Modality is regarded as a potential analyzing method to business text in this paper. The significance of the study is for understanding modal expression in business letter, meanwhile, this is a way to better understand modal logic, and to better use modal device in business let ter.展开更多
The paper conducts Critical Discourse Analysis on the use of Modality in political interviews. The purpose of this study is to investigate whether the use of Motlality is driven by the speakers' ideology, and thus...The paper conducts Critical Discourse Analysis on the use of Modality in political interviews. The purpose of this study is to investigate whether the use of Motlality is driven by the speakers' ideology, and thus helps lo build the power relationships between the two participants. Such a linguistic awareness can inform a capacity to resist and change exploitative and dominating linguistic practices, and it' s an issue of importance to everyone with a concem and interest in the problems of our contemporary society. With such awareness, people can get a more incisive recogni-tion and judgment of the political implications, and correctly acquire new trends in politics and developnient of current affairs.展开更多
The news,a special form of discourse,can easily influence people's emotion and evaluation.Although its characteristics require the reported messages to be objective and fair,there is no absolute objectivity.This p...The news,a special form of discourse,can easily influence people's emotion and evaluation.Although its characteristics require the reported messages to be objective and fair,there is no absolute objectivity.This paper aims to conduct a systematic analysis of finite modal operator and modal adjuncts under the framework of Halliday's systemic-functional grammar.The linguistic data is drawn from two pieces of news reports on hand-foot-mouth disease in English and Chinese.Both qualitative and quantitative research methods are adopted to discover the difference as well as similarity between the two languages with regards to the realization of modality.展开更多
This study investigates the language strategies adopted by the major British political parties in their 2010 general election man-ifestoes to persuade and influence the public in order to win their support.The way in ...This study investigates the language strategies adopted by the major British political parties in their 2010 general election man-ifestoes to persuade and influence the public in order to win their support.The way in which interpersonal meanings are expressed in thetexts is examined in accordance with the three aspects of modality as outlined in Halliday's Systemic Functional Grammar:orientation,value and type.Corresponding with these three aspects,it is found that subjective orientation,median value,and obligation are used ex-tensively by all three parties for persuasive purposes.This demonstrates that modal choices are conditioned or determined by the writers' communicative intentions and by non-linguistic factors such as their social positions and political stances.展开更多
BACKGROUND It was shown in previous studies that high definition endoscopy, high magnification endoscopy and image enhancement technologies, such as chromoendoscopy and digital chromoendoscopy [narrow-band imaging(NBI...BACKGROUND It was shown in previous studies that high definition endoscopy, high magnification endoscopy and image enhancement technologies, such as chromoendoscopy and digital chromoendoscopy [narrow-band imaging(NBI), iScan] facilitate the detection and classification of colonic polyps during endoscopic sessions. However, there are no comprehensive studies so far that analyze which endoscopic imaging modalities facilitate the automated classification of colonic polyps. In this work, we investigate the impact of endoscopic imaging modalities on the results of computer-assisted diagnosis systems for colonic polyp staging.AIM To assess which endoscopic imaging modalities are best suited for the computerassisted staging of colonic polyps.METHODS In our experiments, we apply twelve state-of-the-art feature extraction methods for the classification of colonic polyps to five endoscopic image databases of colonic lesions. For this purpose, we employ a specifically designed experimental setup to avoid biases in the outcomes caused by differing numbers of images per image database. The image databases were obtained using different imaging modalities. Two databases were obtained by high-definition endoscopy in combination with i-Scan technology(one with chromoendoscopy and one without chromoendoscopy). Three databases were obtained by highmagnification endoscopy(two databases using narrow band imaging and one using chromoendoscopy). The lesions are categorized into non-neoplastic and neoplastic according to the histological diagnosis.RESULTS Generally, it is feature-dependent which imaging modalities achieve high results and which do not. For the high-definition image databases, we achieved overall classification rates of up to 79.2% with chromoendoscopy and 88.9% without chromoendoscopy. In the case of the database obtained by high-magnification chromoendoscopy, the classification rates were up to 81.4%. For the combination of high-magnification endoscopy with NBI, results of up to 97.4% for one database and up to 84% for the other were achieved. Non-neoplastic lesions were classified more accurately in general than non-neoplastic lesions. It was shown that the image recording conditions highly affect the performance of automated diagnosis systems and partly contribute to a stronger effect on the staging results than the used imaging modality.CONCLUSION Chromoendoscopy has a negative impact on the results of the methods. NBI is better suited than chromoendoscopy. High-definition and high-magnification endoscopy are equally suited.展开更多
OBJECTIVE: To analyze the efficacy of recurrence prophylaxis using radiation and chemotherapy following bladder conservation surgery for muscle invasive bladder cancer. METHODS: 23 patients with muscle invasive bladde...OBJECTIVE: To analyze the efficacy of recurrence prophylaxis using radiation and chemotherapy following bladder conservation surgery for muscle invasive bladder cancer. METHODS: 23 patients with muscle invasive bladder cancer were treated with radiotherapy combined with bladder mitomycin infusion after bladder conservation surgery (study group). Radiotherapy was given using an external beam at an average dose of 5148 +/- 462 cGy with conventional fractionation. For comparison, 29 similar patients treated with postoperative bladder mitomycin infusion without radiation served as control (control group). All patients were followed up for more than 3 years, an average of 41.6 months (36 - 60 months). RESULTS: The 3-year pelvic recurrent rate of muscle invasive bladder cancer was 17.4% in the study group and 44.8% (P = 0.036) in the control group. The 3-year distant metastasis rates were 17.4% and 24.1%, respectively (P = 0.554). The 3-year overall survival rates were 81.8% and 86.2%, respectively (P = 0.670). Two patients from the study group had their treatment interrupted, one for 3 days and the other for one week due to acute cystitis, while the rest of the patients were able to complete the treatment according to schedule. CONCLUSION: Radiotherapy plus chemotherapy after bladder conservation surgery for muscle invasive bladder cancer can decrease the rate of pelvic recurrence effectively and be used as a realistic adjuvant treatment.展开更多
Zero-shot learning enables the recognition of new class samples by migrating models learned from semanticfeatures and existing sample features to things that have never been seen before. The problems of consistencyof ...Zero-shot learning enables the recognition of new class samples by migrating models learned from semanticfeatures and existing sample features to things that have never been seen before. The problems of consistencyof different types of features and domain shift problems are two of the critical issues in zero-shot learning. Toaddress both of these issues, this paper proposes a new modeling structure. The traditional approach mappedsemantic features and visual features into the same feature space;based on this, a dual discriminator approachis used in the proposed model. This dual discriminator approach can further enhance the consistency betweensemantic and visual features. At the same time, this approach can also align unseen class semantic features andtraining set samples, providing a portion of information about the unseen classes. In addition, a new feature fusionmethod is proposed in the model. This method is equivalent to adding perturbation to the seen class features,which can reduce the degree to which the classification results in the model are biased towards the seen classes.At the same time, this feature fusion method can provide part of the information of the unseen classes, improvingits classification accuracy in generalized zero-shot learning and reducing domain bias. The proposed method isvalidated and compared with othermethods on four datasets, and fromthe experimental results, it can be seen thatthe method proposed in this paper achieves promising results.展开更多
文摘A 68-years old woman presented with ahistory of recurrent fever of 38-39°ac-companied by chills and weakness over the past month.Her physical examination was unremarkable except for an audible 3/6 ejection murmur at the 2nd right intercostal space.Her vital signs were normal with no fever at presentation.Laboratory tests showed elevated white blood count of 11,800cells/mm3 with a remarkable neutrophilia and elevated C-reactive protein of 14 mg/dL.Blood glucose,renal and liver function tests were all normal.
基金This study is supported by the Fundamental Research Funds for the Central Universities of PPSUC under Grant 2022JKF02009.
文摘Face forgery detection is drawing ever-increasing attention in the academic community owing to security concerns.Despite the considerable progress in existing methods,we note that:Previous works overlooked finegrain forgery cues with high transferability.Such cues positively impact the model’s accuracy and generalizability.Moreover,single-modality often causes overfitting of the model,and Red-Green-Blue(RGB)modal-only is not conducive to extracting the more detailed forgery traces.We propose a novel framework for fine-grain forgery cues mining with fusion modality to cope with these issues.First,we propose two functional modules to reveal and locate the deeper forged features.Our method locates deeper forgery cues through a dual-modality progressive fusion module and a noise adaptive enhancement module,which can excavate the association between dualmodal space and channels and enhance the learning of subtle noise features.A sensitive patch branch is introduced on this foundation to enhance the mining of subtle forgery traces under fusion modality.The experimental results demonstrate that our proposed framework can desirably explore the differences between authentic and forged images with supervised learning.Comprehensive evaluations of several mainstream datasets show that our method outperforms the state-of-the-art detection methods with remarkable detection ability and generalizability.
基金the support from the General Program of the Educational Teaching Reform Research Project of Northwestern Polytechnical University(Grant No.2023JGY35)the Guangdong Basic and Applied Basic Research Foundation(Grant No.2022A1515110252)+1 种基金the Double First-class Construction Foundation(Grant No.22GH010616)the Northwestern Polytechnical University of Graduate Student Quality Improvement Program(Grant No.22GZ210101)。
文摘Nowadays,it is extremely urgent for the software engineering education to cultivate the knowledge and ability of database talents in the era of big data.To this end,this paper proposes a talent training teaching modality that integrates knowledge,ability,practice,and innovation(KAPI)for Database System Course.The teaching modality contains three parts:top-level design,course learning process,and course assurance and evaluation.The top-level design sorts out the core knowledge of the course and determines a mixed online and offline teaching platform.The course learning process emphasizes the correspondence transformation relationship between core knowledge points and ability enhancement,and the course is practiced in the form of experimental projects to finally enhance students’innovation consciousness and ability.The assurance and evaluation of the course are based on the outcome-based education(OBE)orientation,which realizes the objective evaluation of students’learning process and final performance.The teaching results of the course in the past 2 years show that the KAPI-based teaching modality has achieved better results.Meanwhile,students are satisfied with the evaluation of the modality.The teaching modality in this paper helps to stimulate students’initiatives,and improve their knowledge vision and practical ability,and thus helps to cultivate innovative and high-quality engineering talents required by the emerging engineering education.
文摘This paper aims at examing how modality values are realized in native and non-native English news reporting and comparing the values they each take.By analyzing,the writer hopes to contribute to the awareness of foreign language learners in terms of the importance of modality values in news analysis and make readers benefit from their reading,writing.
文摘Modality is used to express subjective judgment as well as the speaker’s opinions and attitudes.This paper aims to analyze the reporters’orientation reflected by linguistic modal expressions in English news reports from the perspective of Systemic-Functional Grammar,especially from the perspective of type,value,orientation and polarity.
基金Supported by Samsung Medical Center,No.GF01130081Basic Science Research Program through the National Research Foundation of Korea funded by the Ministry of Education,No.NRF-2015R1D1A1A01060945Marine Biotechnology Program Funded by Ministry of Oceans and Fisheries,Korea,No.20150220
文摘Although the current standard treatment for hepatocellular carcinoma(HCC) with portal vein tumor thrombosis(PVTT) is sorafenib, many previous studies have established the need for a reliable local modality for PVTT control, which is a major cause of liver function deterioration and metastasis. Additionally, there is growing evidence for the prognostic significance of PVTT classification according to the location of tumor thrombosis. Favorable outcomes can be obtained by applying local modalities, including surgery or transarterial chemoembolization, especially in second-order or distal branch PVTT. Rapid control of PVTT could maintain or improve liver function and reduce intrahepatic as well as distant metastasis. Radiotherapy(RT) is one of the main locoregional treatment modalities in oncologic fields, but has rarely been used in HCC because of concerns regarding hepatic toxicity. However, with the development of advanced techniques, RT has been increasingly applied in HCC management. Randomized studies have yet to definitively prove the benefit of RT, but several comparative studies have justified the application of RT in HCC. The value of RT is especially noticeable in HCC with PVTT; several prospective and retrospective studies have reported favorable outcomes, including a 40% to 60% objective response rate and median overall survival of 15 mo to 20 mo in responders. In this review, we evaluate the role of RT as an alternative local modality in HCC with PVTT.
基金Surported by the Funds of Hundred Outsdanding Persons project of Shanghai(97BR029)Science and Technology Commission of Shanghai(984419067)
文摘AIM: To compare the therapeutic effect and significances of multimodality treatment for hepatocellular carcinoma (HCC) with tumor thrombi in portal vein (PVTT). METHODS: HCC patients (n=147) with tumor thrombi in the main portal vein or the first branch of portal vein were divided into four groups by the several therapeutic methods. There were conservative treatment group in 18 out of patients (group A); and hepatic artery ligation(HAL) and/or hepatic artery infusion (HAI) group in 18 patients (group B), in whom postoperative chemoembolization was done periodically; group of removal of HCC with PVTT in 79 (group C) and group of transcatheter hepatic arterial chemoembolization (TACE) or HAI and/or portal vein infusion (PVI) after operation in 32 (group D). RESULTS: The median survival period was 12 months in our series and the 1-,3-, and 5-year survival rates were 44.3%, 24.5% and 15.2%, respectively. The median survival times were 2, 5, 12 and 16 months in group A, B, C and D, respectively. The 1-, 3- and 5-year survival rates were 5.6%, 0% and 0% in group A; 22.2%, 5.6% and 0% in group B; 53.9%, 26.9% and 16.6% in group C; 79.3%, 38.9% and 26.8% in group D, respectively. Significant difference appeared in the survival rates among the groups (P 【 0.05). CONCLUSION: Hepatic resection with removal of tumor thrombi and HCC should increase the curative effects and be encouraged for the prolongation of life span and quality of life for HCC patients with PVTT, whereas the best therapeutic method for HCC with PVTT is with regional hepatic chemotherapy or chemoembolization after hepatic resection with removal of tumor thrombi.
文摘There is a problem of unfairness in allocation of radio resources among heterogeneous mobile terminals in heterogeneous wireless networks. Low-capability mobile terminals (such as single-mode terminals) suffer high call blocking probability whereas high-capability mobile terminals (such as quad-mode terminals) experience very low call blocking probability, in the same heterogeneous wireless network. This paper proposes a Terminal-Modality-Based Joint Call Admission Control (TJCAC) algorithm to reduce this problem of unfairness. The proposed TJCAC algorithm makes call admission decisions based on mobile terminal modality (capability), network load, and radio access technology (RAT) terminal support index. The objectives of the proposed TJCAC algorithm are to reduce call blocking/dropping probability, and ensure fairness in allocation of radio resources among heterogeneous mobile terminals in heterogeneous networks. An analytical model is developed to evaluate the performance of the proposed TJCAC scheme in terms of call blocking/dropping probability in a heterogeneous wireless network. The performance of the proposed TJCAC algorithm is compared with that of other JCAC algorithms. Results show that the proposed algorithm reduces call blocking/dropping probability in the networks, and ensure fairness in allocation of radio resources among heterogeneous terminals.
文摘The number of modes (also known as modality) of a kernel density estimator (KDE) draws lots of interests and is important in practice. In this paper, we develop an inference framework on the modality of a KDE under multivariate setting using Gaussian kernel. We applied the modal clustering method proposed by [1] for mode hunting. A test statistic and its asymptotic distribution are derived to assess the significance of each mode. The inference procedure is applied on both simulated and real data sets.
文摘This study entails a first approach to epistemic modality in Woolf＇s essays. In particular, we will distinguish between assertive and non-assertive epistemic modality. Woolf uses assertive epistemic modality when transmitting her criticism to, sometimes, women＇s inferiority condition in history, revealing Woolf＇s more confident stance. These markers are different from those used in more ＂gentle＂ themes related to reviewing an author and her work. In this second case, non-assertive epistemic modality is more frequent. Being less harsh towards an author＇s surroundings and her literary production, Woolf＇s stance proves less self-assured. The corpus consists of 10 short essays. We also refer to her longer essays A Room of One＇s Own （1929） and Three Guineas 0938）. They were selected bearing in mind their subject-matter. Half of them deal with literature and women writers, their lives and works; the other half ones also have to do with women-related topics, but referring to their position in history and their difficulties to undertake, for example, a literary career. Some concluding remarks indicate the predominance of non-assertive epistemic modality in relation to an intersubjective reading of her texts. This reading favours the inclusion of her audience in her commentary about women writing.
文摘The tenth BRICS Summit was held in Johannesburg,South Africa in 2018,which attracted attention from the whole world.Especially,it is of great importance to the BRICS nations,for it is the first ten years of BRICS,which marks its growth.Meanwhile,this year the Trump administration imposed more strict policies on protectionism.Particularly,the trade war between China and the United States is so intensive.China,as the core member of BRICS has great clout on BRICS,so the trade war between China and US also arouse a heat discussion among the BRICS nations.During the Summit,CGTN invited experts from the five BRICS nations to discuss related topics.Systemic Functional Linguistics,as one of the most influential branches of Linguistics,was firstly established by M.A.K.Halliday,and it has been greatly developed over the past decades.Interpersonal meaning is one of the three meta-functions,which focuses on how addressers use language to communicate,establish and maintain relationships with addressees,and express their opinions.Mood and modality are two basic resources to the realization of interpersonal meaning.Mood is used to represent the interaction of the language users,while modality reflects the utterers’attitudes and judgments.The paper discusses the three aspects of modality:modal operators,modal adjuncts and metaphors of modality.The paper applies the modality system to the analysis of the transcript of BRICS TALK.The author selects the experts’speeches on the trade war between China and US as the data.The research questions are as followed:(1)the characteristics of the modality resources appeared in their talks;(2)the BRICS nations attitudes and stance on trade war and America’s protectionism.
文摘Imagine how many times your attention is distracted by the surrounding sounds or sights irrelevant to your work or study.To maintain concentrated,you have to control yourself intentionally,which is called"attentional control"or"cognitive control"in psychology.An interesting question arises:when we successfully direct our attention away from one visual distractor,can we be immune to another
文摘Researchers in computer science and computer engineering devote a significant part of their efforts on communication and interaction between man and machine. Indeed, with the advent of multimedia and multimodal processing in real time, the computer is no longer considered only as a computational tool, but as a machine for processing, communication, collection and control. Many machines assist and support many activities in daily life. The main objective of this paper is to propose a new methodological solution by modeling an architecture that facilitates the work of multimodal system especially for a fission module. To realize such systems, we rely on ontology to integrate data semantically. Ontologies provide a structured vocabulary usedas support for data representation. This paper provides a better understanding of the fission system and multimodal interaction. We present our architecture and the description of the detection of optimal modalities. This is done by using an ontological model that contains different applicable scenarios and describes the environment where a multimodal system exists.
文摘Business letter with friendly modality is an effective means to represent the best advantage of one's self and firm. The paper in vestigates modality in business letter according to Halliday's view on modality. The modal devices mainly cover modal operator, modal ad junct, and modal cohesion. By means of binary approach modal logic is tentative divided into: perfective and imperfective; positive and neg ative; subjective and objective or explicit and implicit; high, median and low value. Modal devices or modal logic has formal and semantic level. Modality is regarded as a potential analyzing method to business text in this paper. The significance of the study is for understanding modal expression in business letter, meanwhile, this is a way to better understand modal logic, and to better use modal device in business let ter.
文摘The paper conducts Critical Discourse Analysis on the use of Modality in political interviews. The purpose of this study is to investigate whether the use of Motlality is driven by the speakers' ideology, and thus helps lo build the power relationships between the two participants. Such a linguistic awareness can inform a capacity to resist and change exploitative and dominating linguistic practices, and it' s an issue of importance to everyone with a concem and interest in the problems of our contemporary society. With such awareness, people can get a more incisive recogni-tion and judgment of the political implications, and correctly acquire new trends in politics and developnient of current affairs.
文摘The news,a special form of discourse,can easily influence people's emotion and evaluation.Although its characteristics require the reported messages to be objective and fair,there is no absolute objectivity.This paper aims to conduct a systematic analysis of finite modal operator and modal adjuncts under the framework of Halliday's systemic-functional grammar.The linguistic data is drawn from two pieces of news reports on hand-foot-mouth disease in English and Chinese.Both qualitative and quantitative research methods are adopted to discover the difference as well as similarity between the two languages with regards to the realization of modality.
文摘This study investigates the language strategies adopted by the major British political parties in their 2010 general election man-ifestoes to persuade and influence the public in order to win their support.The way in which interpersonal meanings are expressed in thetexts is examined in accordance with the three aspects of modality as outlined in Halliday's Systemic Functional Grammar:orientation,value and type.Corresponding with these three aspects,it is found that subjective orientation,median value,and obligation are used ex-tensively by all three parties for persuasive purposes.This demonstrates that modal choices are conditioned or determined by the writers' communicative intentions and by non-linguistic factors such as their social positions and political stances.
文摘BACKGROUND It was shown in previous studies that high definition endoscopy, high magnification endoscopy and image enhancement technologies, such as chromoendoscopy and digital chromoendoscopy [narrow-band imaging(NBI), iScan] facilitate the detection and classification of colonic polyps during endoscopic sessions. However, there are no comprehensive studies so far that analyze which endoscopic imaging modalities facilitate the automated classification of colonic polyps. In this work, we investigate the impact of endoscopic imaging modalities on the results of computer-assisted diagnosis systems for colonic polyp staging.AIM To assess which endoscopic imaging modalities are best suited for the computerassisted staging of colonic polyps.METHODS In our experiments, we apply twelve state-of-the-art feature extraction methods for the classification of colonic polyps to five endoscopic image databases of colonic lesions. For this purpose, we employ a specifically designed experimental setup to avoid biases in the outcomes caused by differing numbers of images per image database. The image databases were obtained using different imaging modalities. Two databases were obtained by high-definition endoscopy in combination with i-Scan technology(one with chromoendoscopy and one without chromoendoscopy). Three databases were obtained by highmagnification endoscopy(two databases using narrow band imaging and one using chromoendoscopy). The lesions are categorized into non-neoplastic and neoplastic according to the histological diagnosis.RESULTS Generally, it is feature-dependent which imaging modalities achieve high results and which do not. For the high-definition image databases, we achieved overall classification rates of up to 79.2% with chromoendoscopy and 88.9% without chromoendoscopy. In the case of the database obtained by high-magnification chromoendoscopy, the classification rates were up to 81.4%. For the combination of high-magnification endoscopy with NBI, results of up to 97.4% for one database and up to 84% for the other were achieved. Non-neoplastic lesions were classified more accurately in general than non-neoplastic lesions. It was shown that the image recording conditions highly affect the performance of automated diagnosis systems and partly contribute to a stronger effect on the staging results than the used imaging modality.CONCLUSION Chromoendoscopy has a negative impact on the results of the methods. NBI is better suited than chromoendoscopy. High-definition and high-magnification endoscopy are equally suited.
文摘OBJECTIVE: To analyze the efficacy of recurrence prophylaxis using radiation and chemotherapy following bladder conservation surgery for muscle invasive bladder cancer. METHODS: 23 patients with muscle invasive bladder cancer were treated with radiotherapy combined with bladder mitomycin infusion after bladder conservation surgery (study group). Radiotherapy was given using an external beam at an average dose of 5148 +/- 462 cGy with conventional fractionation. For comparison, 29 similar patients treated with postoperative bladder mitomycin infusion without radiation served as control (control group). All patients were followed up for more than 3 years, an average of 41.6 months (36 - 60 months). RESULTS: The 3-year pelvic recurrent rate of muscle invasive bladder cancer was 17.4% in the study group and 44.8% (P = 0.036) in the control group. The 3-year distant metastasis rates were 17.4% and 24.1%, respectively (P = 0.554). The 3-year overall survival rates were 81.8% and 86.2%, respectively (P = 0.670). Two patients from the study group had their treatment interrupted, one for 3 days and the other for one week due to acute cystitis, while the rest of the patients were able to complete the treatment according to schedule. CONCLUSION: Radiotherapy plus chemotherapy after bladder conservation surgery for muscle invasive bladder cancer can decrease the rate of pelvic recurrence effectively and be used as a realistic adjuvant treatment.
文摘Zero-shot learning enables the recognition of new class samples by migrating models learned from semanticfeatures and existing sample features to things that have never been seen before. The problems of consistencyof different types of features and domain shift problems are two of the critical issues in zero-shot learning. Toaddress both of these issues, this paper proposes a new modeling structure. The traditional approach mappedsemantic features and visual features into the same feature space;based on this, a dual discriminator approachis used in the proposed model. This dual discriminator approach can further enhance the consistency betweensemantic and visual features. At the same time, this approach can also align unseen class semantic features andtraining set samples, providing a portion of information about the unseen classes. In addition, a new feature fusionmethod is proposed in the model. This method is equivalent to adding perturbation to the seen class features,which can reduce the degree to which the classification results in the model are biased towards the seen classes.At the same time, this feature fusion method can provide part of the information of the unseen classes, improvingits classification accuracy in generalized zero-shot learning and reducing domain bias. The proposed method isvalidated and compared with othermethods on four datasets, and fromthe experimental results, it can be seen thatthe method proposed in this paper achieves promising results.
