Heart transplantation remains the gold standard in the treatment of end-stage heart failure(HF).Heart transplantation patients present lower exercise capacity due to cardiovascular and musculoskeletal alterations lead...Heart transplantation remains the gold standard in the treatment of end-stage heart failure(HF).Heart transplantation patients present lower exercise capacity due to cardiovascular and musculoskeletal alterations leading thus to poor quality of life and reduction in the ability of daily self-service.Impaired vascular function and diastolic dysfunction cause lower cardiac output while decreased skeletal muscle oxidative fibers,enzymes and capillarity cause arteriovenous oxygen difference,leading thus to decreased peak oxygen uptake in heart transplant recipients.Exercise training improves exercise capacity,cardiac and vascular endothelial function in heart transplant recipients.Pre-rehabilitation regular aerobic or combined exercise is beneficial for patients with end-stage HF awaiting heart transplantation in order to maintain a higher fitness level and reduce complications afterwards like intensive care unit acquired weakness or cardiac cachexia.All hospitalized patients after heart transplantation should be referred to early mobilization of skeletal muscles through kinesiotherapy of the upper and lower limbs and respiratory physiotherapy in order to prevent infections of the respiratory system prior to hospital discharge.Moreover,all heart transplant recipients after hospital discharge who have not already participated in an early cardiac rehabilitation program should be referred to a rehabilitation center by their health care provider.Although high intensity interval training seems to have more benefits than moderate intensity continuous training,especially in stable transplant patients,individualized training based on the abilities and needs of each patient still remains the most appropriate approach.Cardiac rehabilitation appears to be safe in heart transplant patients.However,long-term follow-up data is incomplete and,therefore,further high quality and adequately-powered studies are needed to demonstrate the long-term benefits of exercise training in this population.展开更多
目的比较中等强度持续运动(moderate-intensity continuous exercise,MCE)与膈肌吸气肌肉训练(inspiratory muscle training,IMT)对稳定期支气管哮喘患者肺功能、生活质量、运动能力、依从性的影响。方法2021年1月-6月招募60例确诊支气...目的比较中等强度持续运动(moderate-intensity continuous exercise,MCE)与膈肌吸气肌肉训练(inspiratory muscle training,IMT)对稳定期支气管哮喘患者肺功能、生活质量、运动能力、依从性的影响。方法2021年1月-6月招募60例确诊支气管哮喘至少6个月以上的患者,随机分为MCE组和IMT组,各30例。MCE组每周至少5次中等强度步行训练。IMT组被指导进行膈肌呼吸结合吸气阻力训练,每周5次。康复训练前后分别测定肺功能、哮喘控制问卷(asthma control questionnaire,ACQ)、哮喘生活质量问卷(asthma quality of life questionnaire,AQLQ)、6 min步行试验(6-minute walk test,6MWT)及依从性评分等。结果2组在康复训练后PEF,ACQ、AQLQ、6WMT步行距离较康复训练前均得到改善,差异有统计学意义(P<0.05),且康复训练后MCE组6WMT步行距离优于IMT组,依从性评分MCE组高于IMT组,差异有统计学意义(P<0.05)。结论MCE与IMT康复训练均有助于支气管哮喘患者生活质量、运动能力的改善,但MCE在步行运动能力,依从性评分上更优,值得深入研究与推广。展开更多
目的:对比分析高强度间歇训练(HIIT)和中等强度持续训练(MICT)对心血管患者血脂水平的影响,探究有氧运动改善心血管疾病危险因素的价值。方法:计算机检索PubMed、Cochrane Library、Web of Science、中国知网(CNKI)和中国生物医学文献...目的:对比分析高强度间歇训练(HIIT)和中等强度持续训练(MICT)对心血管患者血脂水平的影响,探究有氧运动改善心血管疾病危险因素的价值。方法:计算机检索PubMed、Cochrane Library、Web of Science、中国知网(CNKI)和中国生物医学文献数据库(CMB)中关于HIIT和MICT对心血管危险因素影响的随机对照实验(RCTs)成果,检索时限为建库至2023年2月,通过文献质量评价提取数据,采用Sata15.0、RevMan5.3统计软件进行Meta分析。结果:纳入文献11篇,涉及受试者327名。实验组(HIIT)与对照组(MICT)相比,对心血管改善作用相近,对高密度脂蛋白(HDL-C)改善程度略优于对照组(WMD=0.062,95%CI,0.005-0.119,P=0.033),对低密度脂蛋白(LDL-C)改善程度无显著差异(WMD=-0.001,95%CI,-0.159-0.158,P=0.995),对总胆固醇(TC)改善程度无显著差异(WMD=0.021,95%CI,-0.177-0.220,P=0.834),对甘油三酯(TRG)改善程度不及对照组(WMD=-0.138,95%CI,-0.262--0.014,P=0.03),研究中没有提示明显异质性和发表偏倚。结论:有氧运动对心血管患者有益,HIIT在血脂改善方面对比MICT没有显著差异,并不能带来更大效益,但HIIT作为新手段,耗时短,效率高,有效降低心血管疾病风险,预防或延缓心血管疾病发展,在临床和亚临床中值得推广。展开更多
文摘Heart transplantation remains the gold standard in the treatment of end-stage heart failure(HF).Heart transplantation patients present lower exercise capacity due to cardiovascular and musculoskeletal alterations leading thus to poor quality of life and reduction in the ability of daily self-service.Impaired vascular function and diastolic dysfunction cause lower cardiac output while decreased skeletal muscle oxidative fibers,enzymes and capillarity cause arteriovenous oxygen difference,leading thus to decreased peak oxygen uptake in heart transplant recipients.Exercise training improves exercise capacity,cardiac and vascular endothelial function in heart transplant recipients.Pre-rehabilitation regular aerobic or combined exercise is beneficial for patients with end-stage HF awaiting heart transplantation in order to maintain a higher fitness level and reduce complications afterwards like intensive care unit acquired weakness or cardiac cachexia.All hospitalized patients after heart transplantation should be referred to early mobilization of skeletal muscles through kinesiotherapy of the upper and lower limbs and respiratory physiotherapy in order to prevent infections of the respiratory system prior to hospital discharge.Moreover,all heart transplant recipients after hospital discharge who have not already participated in an early cardiac rehabilitation program should be referred to a rehabilitation center by their health care provider.Although high intensity interval training seems to have more benefits than moderate intensity continuous training,especially in stable transplant patients,individualized training based on the abilities and needs of each patient still remains the most appropriate approach.Cardiac rehabilitation appears to be safe in heart transplant patients.However,long-term follow-up data is incomplete and,therefore,further high quality and adequately-powered studies are needed to demonstrate the long-term benefits of exercise training in this population.
文摘目的比较中等强度持续运动(moderate-intensity continuous exercise,MCE)与膈肌吸气肌肉训练(inspiratory muscle training,IMT)对稳定期支气管哮喘患者肺功能、生活质量、运动能力、依从性的影响。方法2021年1月-6月招募60例确诊支气管哮喘至少6个月以上的患者,随机分为MCE组和IMT组,各30例。MCE组每周至少5次中等强度步行训练。IMT组被指导进行膈肌呼吸结合吸气阻力训练,每周5次。康复训练前后分别测定肺功能、哮喘控制问卷(asthma control questionnaire,ACQ)、哮喘生活质量问卷(asthma quality of life questionnaire,AQLQ)、6 min步行试验(6-minute walk test,6MWT)及依从性评分等。结果2组在康复训练后PEF,ACQ、AQLQ、6WMT步行距离较康复训练前均得到改善,差异有统计学意义(P<0.05),且康复训练后MCE组6WMT步行距离优于IMT组,依从性评分MCE组高于IMT组,差异有统计学意义(P<0.05)。结论MCE与IMT康复训练均有助于支气管哮喘患者生活质量、运动能力的改善,但MCE在步行运动能力,依从性评分上更优,值得深入研究与推广。
文摘目的:对比分析高强度间歇训练(HIIT)和中等强度持续训练(MICT)对心血管患者血脂水平的影响,探究有氧运动改善心血管疾病危险因素的价值。方法:计算机检索PubMed、Cochrane Library、Web of Science、中国知网(CNKI)和中国生物医学文献数据库(CMB)中关于HIIT和MICT对心血管危险因素影响的随机对照实验(RCTs)成果,检索时限为建库至2023年2月,通过文献质量评价提取数据,采用Sata15.0、RevMan5.3统计软件进行Meta分析。结果:纳入文献11篇,涉及受试者327名。实验组(HIIT)与对照组(MICT)相比,对心血管改善作用相近,对高密度脂蛋白(HDL-C)改善程度略优于对照组(WMD=0.062,95%CI,0.005-0.119,P=0.033),对低密度脂蛋白(LDL-C)改善程度无显著差异(WMD=-0.001,95%CI,-0.159-0.158,P=0.995),对总胆固醇(TC)改善程度无显著差异(WMD=0.021,95%CI,-0.177-0.220,P=0.834),对甘油三酯(TRG)改善程度不及对照组(WMD=-0.138,95%CI,-0.262--0.014,P=0.03),研究中没有提示明显异质性和发表偏倚。结论:有氧运动对心血管患者有益,HIIT在血脂改善方面对比MICT没有显著差异,并不能带来更大效益,但HIIT作为新手段,耗时短,效率高,有效降低心血管疾病风险,预防或延缓心血管疾病发展,在临床和亚临床中值得推广。
