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Practice of Pediatric Neurosurgery at the “Hôpital SpécialiséMère-Enfant Blanche Gomes” in the Republic of the Congo
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作者 Boukaka Kala Rel Gerald Kinata Bambino Sinclair Brice +4 位作者 Ekouele Mbaki Hughes Brieux Bingui Outman Pascal Diogène Boukassa Léon Moukouengo Nee Kaya Fleur Patricia Mabiala Babela Jean Robert 《Open Journal of Modern Neurosurgery》 2023年第1期41-50,共10页
Introduction: Pediatric Neurosurgery is a growing specialty in its own right worldwide. Its practice in sub-Saharan Africa remains confronted with many challenges, notably the absence of a pediatric neurosurgeon, the ... Introduction: Pediatric Neurosurgery is a growing specialty in its own right worldwide. Its practice in sub-Saharan Africa remains confronted with many challenges, notably the absence of a pediatric neurosurgeon, the lack of a dedicated service and the absence of multidisciplinary pediatric collaboration (neuroanesthesist, neurologist, oncologist and psychotherapist). The objective of this preliminary study is to describe the practice of pediatric neurosurgery at the HSMEBG and to present perspectives for its improvement. Methods: This is a retrospective, monocentric, descriptive study covering the period from March 2021 to March 2022 at the Pediatric Surgery Department of the HSMEBG. Résults: During the study period, 50 children were hospitalized for a neurosurgical condition. The sex ratio was 1.77. The average age was 6 years with extremes of 2 weeks and 16 years. Most children were from the emergency department (46%). Computed tomography (CT) was performed in 35 patients (70%), magnetic resonance imaging (MRI) in 4% and plain radiography in two patients (8%). Malformative, traumatic (cranial and spinal) and tumor pathology were the most frequent with 42%, 36% and 12% respectively. Twenty-six patients were operated (52%). We recorded one postoperative infection (2.5%). The overall mortality was 8% (N = 4). Conclusion: This preliminary study allowed us to identify the epidemiological and clinical profile of the patients treated in our context as well as the therapeutic approach. Malformative pathology remains the most frequent, followed by traumatic and tumor pathology. The development of the practice of this discipline remains a challenge in our working conditions and requires the training of pediatric neurosurgeons and dedicated paramedical staff. 展开更多
关键词 neurosurgery Pediatric PRACTICE BRAZZAVILLE
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Patient Safety Risks and Measures for Pediatric Neurosurgery Nursing
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作者 Lili Jiang Weifang Yang Song Zhang 《Journal of Clinical and Nursing Research》 2023年第3期8-12,共5页
The aim of this study was to determine the patient safety risks and measures for pediatric neurosurgery nursing.A total of 564 pediatric patients admitted to the hospital from June 2020 to June 2023 under the neurosur... The aim of this study was to determine the patient safety risks and measures for pediatric neurosurgery nursing.A total of 564 pediatric patients admitted to the hospital from June 2020 to June 2023 under the neurosurgery department were included in this study.We analyzed the safety incidents in pediatric neurosurgery nursing and their causes and proposed corresponding measures for pediatric neurosurgery nursing in hope to reduce the occurrence of patient safety incidents in pediatric neurosurgery nursing and establish harmonious nurse-patient relationships. 展开更多
关键词 neurosurgery Pediatric patients Patient safety risks COUNTERMEASURES
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Neurosurgery:颈动脉内膜剥脱术后同侧瞳孔散大是怎么回事?
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作者 杨中华 《中国卒中杂志》 2018年第1期71-71,共1页
急性瞳孔散大往往提示脑疝,是神经外科最严重的临床征象。颈动脉内膜剥脱术(carotid endarterectomy,CEA)后,急性瞳孔散大意味着再灌注出血引起占位效应压迫动眼神经。CEA手术后出血非常罕见,不足0.5%。
关键词 瞳孔散大 手术后 neurosurgery
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Mycoplasma hominis meningitis after operative neurosurgery:A case report and review of literature 被引量:3
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作者 Nian-Long Yang Xiao Cai +3 位作者 Qing Que Hua Zhao Kai-Long Zhang Sheng Lv 《World Journal of Clinical Cases》 SCIE 2022年第3期1131-1139,共9页
BACKGROUND Mycoplasma hominis(M.hominis),which causes central nervous system infections in adults,is very rare.It is also relatively difficult to culture mycoplasma and culturing requires special media,resulting in a ... BACKGROUND Mycoplasma hominis(M.hominis),which causes central nervous system infections in adults,is very rare.It is also relatively difficult to culture mycoplasma and culturing requires special media,resulting in a high rate of clinical underdiagnosis.Therefore,clinicians often treat patients based on their own experience before obtaining pathogenic results and may ignore infections with atypical pathogens,thus delaying the diagnosis and treatment of patients and increasing the length of hospital stay and costs.CASE SUMMARY A 44-year-old man presented to the hospital complaining of recurrent dizziness for 1 year,which had worsened in the last week.After admission,brain magnetic resonance imaging(MRI)revealed a 7.0 cm×6.0 cm×6.1 cm lesion at the skull base,which was irregular in shape and had a midline shift to the left.Based on imaging findings,meningioma was our primary consideration.After lesion resection,the patient had persistent fever and a diagnosis of suppurative meningitis based on cerebrospinal fluid(CSF)examination.The patient was treated with the highest level of antibiotics(meropenem and linezolid),but the response was ineffective.Finally,M.hominis was detected by next-generation metagenomic sequencing(mNGS)in the CSF.Therefore,we changed the antibiotics to moxifloxacin 0.4 g daily combined with doxycycline 0.1 g twice a day for 2 wk,and the patient had a normal temperature the next day.CONCLUSION Mycoplasma meningitis after neurosurgery is rare.We can use mNGS to detect M.hominis in the CSF and then provide targeted treatment. 展开更多
关键词 neurosurgery Central nervous system infections MENINGITIS Mycoplasma hominis Next-generation sequencing Case report
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Preliminary Recommendations for Surgical Practice of Neurosurgery Department in the Central Epidemic Area of 2019 Coronavirus Infection 被引量:1
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作者 Yu-tang TAN Jun-wen WANG +5 位作者 Kai ZHAO Lin HAN Hua-qiu ZHANG Hong-quan NIU Kai SHU Ting LEI 《Current Medical Science》 SCIE CAS 2020年第2期281-284,共4页
Since December 2019,an outbreak of coronavirus disease 2019(COVID-19)has.posed significant threats to the public health and life in China.Unlike the other 6 identified coronaviruscs,the SARS-Cov-2 has a high infectiou... Since December 2019,an outbreak of coronavirus disease 2019(COVID-19)has.posed significant threats to the public health and life in China.Unlike the other 6 identified coronaviruscs,the SARS-Cov-2 has a high infectious rate,a long incubation period and a variety of manifestations.In the absence of effective treatments for the virus,it becomes extremely urgent to develop scientific and standardized proposals for prevention and control of virus transmission.Hereby we focused on the surgical practice in Neurosurgery Department,Tongji Hospital,Wuhan,and drafted several recommendations based on the latest relevant guidelines and our experience.These recommendations have helped us until now to achieve'zero infection'of doctors and nurses in our department,we would like to share them with other medical staff of neurosurgery to fight 2019-nCoV infection. 展开更多
关键词 SARS-CoV-2 neurosurgery Diagnosis Treatment Prevention
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Postoperative Outcome in Children Aged between 6 and 10 Years in Major Abdominal Surgery, Neurosurgery and Orthopedic Surgery 被引量:2
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作者 Claudine Kumba 《Open Journal of Pediatrics》 2021年第4期636-645,共10页
<strong>Background:</strong> <span "=""><span>Anticipating postoperative evolution in surgical patients is an important issue in our daily practice. We demonstrated in a previous... <strong>Background:</strong> <span "=""><span>Anticipating postoperative evolution in surgical patients is an important issue in our daily practice. We demonstrated in a previous study </span><span>that there were multiple predictors of postoperative outcome, including</span><span> American Society of Anesthesiologists status (ASA), transfusion, emergency, surgery and age. A secondary analysis describing intraoperative and postoperative outcomes was undertaken in children aged between 6 and 10 years old included in the initial study. </span><b><span>Objective: </span></b><span>To describe intraoperative and postoperative outcomes in children aged between 6 and 10 years old included in the initial cohort in abdominal surgery, neurosurgery and orthopedics. </span><b><span>Methods: </span></b><span>The secondary analysis of postoperative outcomes in children aged between 6 and 10 years old w</span></span><span>as</span><span "=""><span> retrospectively included in the initial study of 594 patients. The study was approved by the Ethics Committee. </span><b><span>Results: </span></b><span>There were 88 patients with a mean age of 98.7 ±</span></span><span "=""> </span><span "=""><span>13.8 months. The most common surgical interventions were scoliosis in 23 patients (26.1%), limb tumor resection in 8 patients (9.1%), femoral osteotomy in 6 patients (6.8%), intracerebral tumor resection in 6 patients (6.8%), intestinal resection in 5 patients (5.6%), Chiari’s malformation in 4 patients (4.5%), pelvic osteotomy in 4 patients (4.5%) and renal transplantation in 4 patients (4.5%). Most patients (45%) were American Society of Anesthesiologists grade 3 (ASA 3), and 13 (14.8%) were ASA grade 4. Twenty-two (25%) patients had intraoperative and/or postoperative complications (organ dysfunction or sepsis). Two patients (2.3%) had intraoperative hemorrhage, 1 patient (1.1%) had intraoperative difficult intubation, and 1 patient experienced intraoperative anaphy</span><span>laxis. Nine patients (10.2%) had postoperative neurologic failure, and 2</span><span> (2.3%) had postoperative cardio-circulatory failure. Three patients (3.4%) had postoperative septicemia, 2 patients (2.3%) had postoperative pulmonary and urinary sepsis, and 1 patient (1.1%) had postoperative abdominal sepsis. 3 patients (3.4%) had re-operations. 42</span></span><span "=""> </span><span>(47.7%) patients had intra-operative transfusion. There was 1 in-hospital death (1.1%). The median total length of hospital stay was 9 days [5</span><span "=""> </span><span>-</span><span "=""> </span><span "=""><span>16]. </span><b><span>Conclusion: </span></b><span>Twenty-five percent of the patients had intraoperative and/or postoperative complications, and most of them were ASA grade </span></span><span>3</span><span> 3. Integrating goal-directed therapies to optimize intraoperative management in these patients could be necessary to improve postoperative outcomes in surgical pediatric patients. 展开更多
关键词 CHILDREN Abdominal Surgery neurosurgery ORTHOPEDICS OUTCOME Goal-Directed Therapies
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Prolonged coexistent central diabetes insipidus and cerebral salt wasting syndrome following neurosurgery 被引量:1
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作者 D. López de Lara B. Joyanes +3 位作者 A. Llaneza O. Pérez B. Llorente I. Runkle 《Open Journal of Pediatrics》 2013年第2期74-77,共4页
The coexistence of different water homeostasis abnormalities following neurosurgery represents a diagnostic and therapeutic challenge for intensive care units. This paper reports the case of a 13 year-old boy who unde... The coexistence of different water homeostasis abnormalities following neurosurgery represents a diagnostic and therapeutic challenge for intensive care units. This paper reports the case of a 13 year-old boy who underwent surgery for a suprasellar tumour and, immediately after surgery, developed a cerebral abscess, persistent diabetes insipidus (DI) as well as cerebral salt wasting syndrome (CSWS). The early onset of CSWS following DI has been associated with a poor prognosis and increased mortality. In cases in which these abnormalities coexist, the increased polyuria secondary to the rise in natriuresis associated with CSWS might be erroneously interpreted as a sign of poor control of the DI, thereby leading to therapeutic mistakes. Treatment basically consists of restoring electrolytes and the joint administration of desmopressin and fludrocortisone. 展开更多
关键词 ELECTROLYTE DISORDER Diabetes Insipidus CEREBRAL Salt WASTING Syndrome neurosurgery
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Comparison of Nasal and Frontal BIS Monitoring in Neurosurgery: Does the Site of Sensor Placement Affect the BIS Values? 被引量:1
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作者 Konul Hajiyeva Basak Ceyda Meco +3 位作者 Cigdem Yildirim Guclu Dilek Yorukoglu Beyza Doganay Mehmet Oral 《International Journal of Clinical Medicine》 2021年第3期108-114,共7页
<strong>Background and Goal of Study:</strong> Intraoperative awareness is a serious but preventable complication of general anaesthesia. Bispectral index (BIS) is the most widely used method monitoring an... <strong>Background and Goal of Study:</strong> Intraoperative awareness is a serious but preventable complication of general anaesthesia. Bispectral index (BIS) is the most widely used method monitoring anaesthesia depth. BIS monitoring requires attachment of forehead sensors, which poses a challenge when the surgical field involves the forehead. We aimed to compare the gold standard forehead position of BIS sensors with an alternative position across the nasal dorsum for neurosurgical procedures.<strong> Materials and Methods: </strong>After ethical committee approval and informed consent were obtained, 62 patients were enrolled in this prospective observational study. Frontal and nasal BIS values were compared in all patients.<strong> Results and Discussion:</strong> The mean BIS value from frontal versus nasal sensors was 49 ± 22 and 49 ± 21 respectively (n: 62). These values were statistically correlated (ICC 0.78, p < 0.001) indicating that nasal BIS measurement does not present a disadvantage for routine use when needed. <strong>Conclusion:</strong> Our data reveal that for measuring anesthesia depth, BIS sensor placement on the nasal dorsum shows comparable efficiency in comparison to standard frontal 展开更多
关键词 BIS NEUROMONITORING neurosurgery
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27th Congress of the European Society for Pediatric Neurosurgery
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《中国现代神经疾病杂志》 CAS 北大核心 2020年第3期229-229,共1页
Time:May 3-6,2020,Venue:Athens,Greece,Website:https://www.erasmus.gr/microsites/1179The 27th Congress of the European Society for Pediatric Neurosurgery(ESPN)will take place in Athens,Greece on May 3-6,2020.ESPN aims ... Time:May 3-6,2020,Venue:Athens,Greece,Website:https://www.erasmus.gr/microsites/1179The 27th Congress of the European Society for Pediatric Neurosurgery(ESPN)will take place in Athens,Greece on May 3-6,2020.ESPN aims to organize an outstanding scientific and educational congress to facilitate the spread and exchange of knowledge,skills and attitudes,between experts,researchers,clinicians and trainees,and to continue the development of pediatric neurosurgery in Europe. 展开更多
关键词 the European Society Pediatric neurosurgery KNOWLEDGE
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Emergency treatment and anesthesia management of internal carotid artery injury during neurosurgery:Four case reports
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作者 Jie Wang Yu-Ming Peng 《World Journal of Clinical Cases》 SCIE 2022年第27期9865-9872,共8页
BACKGROUND During skull base surgery,intraoperative internal carotid artery(ICA) injury is a catastrophic complication that can lead to fatal blood loss or secondary cerebral ischemia.Appropriate management of ICA inj... BACKGROUND During skull base surgery,intraoperative internal carotid artery(ICA) injury is a catastrophic complication that can lead to fatal blood loss or secondary cerebral ischemia.Appropriate management of ICA injury plays a crucial role in the prognosis of patients.Neurosurgeons have reported multiple techniques and management strategies;however,the literature on managing this complication from the anesthesiologist’s perspective is limited,especially in the aspect of circulation management and airway management when patients need transit for further endovascular treatment.CASE SUMMARY We describe 4 cases of ICA injury during neurosurgery;there were 3 cases of pathologically proven pituitary adenoma and 1 case of cavernous sinus endothelial meningioma.After the onset of ICA injury,all four patients were immediately transferred for endovascular therapy under general anesthesia with vital signs monitored and mechanical ventilation.Three patients were transferred to the hybrid operating room,and one patient was transferred to the catheter operating room.Three patients underwent covered stent implantation,and one patient underwent embolization.All four patients experienced hypovolemic shock and received blood products infusion and vasoactive drugs to maintain stable circulation.After the neurosurgery,one patient was extubated and returned to the ward,and the other three were delayed tracheal extubation and returned to the intensive care unit.One patient died from serious neurological complications after 62 d in the hospital,but the other three showed good clinical outcomes.CONCLUSION ICA injury imposes a high risk of massive hemorrhage and subsequent infarction.Immediate treatment is critical and requires interdisciplinary collaboration among neurosurgeons,anesthesiologists,and interventional neuroradiologists.Effective hemostatic methods,stable hemodynamics sufficient to ensure perfusion of vital organs,airway safety during transit,rapid localization and implementation of appropriate measures to occlude the damaged vessel are strong guarantees of patient safety. 展开更多
关键词 COMPLICATION Internal carotid artery injury neurosurgery Anesthesia Management Literature review Case reports
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Importance of the telemedicine network for neurosurgery in Slovenia
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作者 Tomaz Velnar Tilen Zele Roman Bosnjak 《World Journal of Methodology》 2019年第1期20-25,共6页
The number of invasive procedures in medicine is increasing,as is the employment of new technological achievements.In the era of informationcommunication technology,one such achievement is also the telemedicine networ... The number of invasive procedures in medicine is increasing,as is the employment of new technological achievements.In the era of informationcommunication technology,one such achievement is also the telemedicine network.In Slovenia,it is known as the Telekap(TeleStroke) network,which was primarily designed for fast and efficient management of stroke patients.In the neurosurgical community,the system is frequently used also for conveying vital information regarding subarachnoid haemorrhage and trauma.Especially in neurosurgical emergencies,this communication system offers thorough information about the extent and location of bleeding and facilitates the preoperative planning of neurosurgical interventions.From our experience so far,the system should be expanded to other neuro-centres as well to all neurosurgery departments in order to facilitate patient management,their acute hospital care,and inter-speciality collaboration. 展开更多
关键词 TELEMEDICINE neurosurgery NEUROSURGICAL PLANNING NEUROIMAGING Slovenia
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The contribution of functional neurosurgery to the understanding of the physiopathology of Parkinson’s disease
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作者 Juan Antonio Barcia Fernando Alonso-Frech 《Advances in Parkinson's Disease》 2013年第3期88-95,共8页
Functional neurosurgery is nowadays a recognized treatment for advanced Parkinson’s disease with pharmacologically uncontrolled symptoms. This procedure brings us the unique opportunity to deepen in the knowledge of... Functional neurosurgery is nowadays a recognized treatment for advanced Parkinson’s disease with pharmacologically uncontrolled symptoms. This procedure brings us the unique opportunity to deepen in the knowledge of PD’s physiopathology by recording patients’ neural activity, and possibly in the future it will let us select the appropriate target and the optimal chronic stimulation pattern. 展开更多
关键词 Parkinson’s Disease Functional neurosurgery OSCILLATORY Activity
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INTERNATIONAL NEUROSURGERY MEETING
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《中华神经外科疾病研究杂志》 CAS 2004年第1期32-32,共1页
关键词 WWW INTERNATIONAL neurosurgery MEETING IL
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Anesthetic Practice in Neurosurgery at University Hospital of Brazzaville (Congo)
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作者 Marie Elombila Hugues Brieux Ekouele Mbaki +1 位作者 Gilbert Fabrice Otiobanda Gilles Niengo Outsouta 《Neuroscience & Medicine》 2017年第4期77-86,共10页
Aim: To evaluate the anesthetic management of neurosurgical patients in University Hospital of Brazzaville. Materials and methods: We performed a transversal and descriptive study during the period from January to Jun... Aim: To evaluate the anesthetic management of neurosurgical patients in University Hospital of Brazzaville. Materials and methods: We performed a transversal and descriptive study during the period from January to June 2015 into operating room of the University Hospital of Brazzaville. 60 cases of anesthesia have been analyzed. Results: The neurosurgery represented 2.88% of the activity of the operating room in University Hospital of Brazzaville. The average age was 44.7 ± 18.36 years old. The sex ratio was 1.07. The scheduled interventions have concerned 83.4% of cases. Surgical indications were concerned the spine degenerative disease and spinal trauma in 40% and 18.3% of cases respectively. The patients classified ASA I and II were most represented in 40% and 46.7% of cases respectively. General anesthesia was used in 98.4% of cases. The peroperative complications were represented by arterial hypotension (31.7%), hemorrhage (11.7%), bradycardia (5%), difficult intubation (3.3%) and one case of peroperative cardiac arrest. The blood transfusion rate was 18.7%. The stay in ICU concerned 8.3% of the cases. We recorded three cases (5%) of death in our series. Conclusion: The neuroanesthesia knows an evolution in our country because of increasing number of neurosurgeons;it’s necessary to train medical staff in her practice. 展开更多
关键词 ANESTHESIA neurosurgery PERIOPERATIVE Period
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Establishment and management of neurosurgery emergency observation ward during the COVID‑19 epidemic period
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作者 Hui‑Ting NIE Zong‑Ying ZOU Hui ZHANG 《Journal of Integrative Nursing》 2020年第3期138-143,共6页
During the COVID‑19 epidemic period,the front‑line antiepidemic departments have attracted much attention.However,to meet people’s daily needs for the diagnosis and treatment,emergency department and intensive care u... During the COVID‑19 epidemic period,the front‑line antiepidemic departments have attracted much attention.However,to meet people’s daily needs for the diagnosis and treatment,emergency department and intensive care unit are also the focus of work to control the source of infection,cut off the transmission route,and reduce the risk of novel coronavirus transmission while treating patients.In order to further strengthen the management,our department of neurosurgery took active measures in the emergency treatment for patients and summarized the coping strategies and relevant experience from the aspects of establishment of emergency observation wards,medical staff management,patients and family management,daily environment and object surface disinfection management,material management,and nursing quality management,hoping to provide reference for the nursing management of emergency wards after the outbreak of public health emergencies. 展开更多
关键词 COVID‑19 neurosurgery emergency observation wards nursing management public health emergencies
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Neurocritical Care Training for the Neurosurgery Resident
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作者 Paul EKaloostian Jennifer Kim Howard Yonas 《Open Journal of Modern Neurosurgery》 2013年第2期9-17,共9页
Introduction: Recent data has associated favorable outcomes in patients who were treated in a “semi-closed” intensive care unit and attended to by a devoted team of neurointensivists as opposed to the neurosurgeons.... Introduction: Recent data has associated favorable outcomes in patients who were treated in a “semi-closed” intensive care unit and attended to by a devoted team of neurointensivists as opposed to the neurosurgeons. This has led many to question the need for dedicated critical care education in the neurosurgical residency training program. Our aim was to determine what current neurosurgery residents and program directors/chairman thoughts were on NCC education in neurosurgical resident training, and to discuss possible methods to allow for collaboration between the NCC team and the neurosurgeons. Methods: Surveys were sent out electronically to all residency programs. Thirty-nine responses from junior residents, 36 responses from senior/chief residents, and eight responses from program directors/chairman were obtained. Results: No statistical difference between the majority responses of the different level residents, and between program directors/chairman and combined resident responses. Conclusions: Clearly, neurosurgery residents of all levels and program directors/chairman value NCC education and see a valuable role for this knowledge in their future. Most residents however do not want to spend an additional year of fellowship training to become certified neurointensivists. We discuss the role of NCC education in residency training and possible solutions to allow collaboration between the NCC team and the neurosurgical team. 展开更多
关键词 Neurocritical CARE neurosurgery RESIDENT neurosurgery SURVEY NEUROINTENSIVIST
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Intraoperative magnetic resonance imaging in neurosurgery and anesthetic considerations
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作者 Nidhi Gupta Girija Prasad Rath 《World Journal of Anesthesiology》 2014年第2期174-180,共7页
Currently, magnetic resonance imaging(MRI) is the only imaging modality available which is capable of acquiring intra-operative images frequently with acceptable spatial and contrast resolution. However, the incorpora... Currently, magnetic resonance imaging(MRI) is the only imaging modality available which is capable of acquiring intra-operative images frequently with acceptable spatial and contrast resolution. However, the incorporation of MRI technology into the operating room requires special anesthetic considerations. It may include various aspects such as transport, remote location anesthesia, strong electromagnetic field, use of approved items, equipment counts, possible emergencies, and surgery in awake patients. The patient safety may be compromised by health-related, equipment-related, and procedure-related risks. Direct patient observation may be compromised by acoustic noise, darkened environment, obstructed line of sight, and distractions along with difficult access to the patient for airway management. Most often, the patient's head will be 180° away from the anesthesiologist during the procedure. Several monitors exist that are designed for conditional use in a MR environment. The general design criterion in these monitors is to eliminate conductors that carry electrical signals for monitoring physiologic parameters of the patient. General anesthesia requires an extended anesthetic circuit for ventilation maintenance and drug administration because the patient is located farther from the anesthesia machine than in traditional operating room settings. Dead space creates a time delay before the volatile anesthetic and drugs are administered and when expected effects can be observed. Therefore, the attending anaesthesiologists must understand the above aspects for safe conduct of neurosurgical procedures by minimizing MRI associated accidents while assuring optimal patient vigilance. 展开更多
关键词 INTRAOPERATIVE magnetic RESONANCE imaging ELECTROMAGNETIC field Safety ANESTHESIA neurosurgery
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Intracerebral Microdialysis in Neurosurgery for Obsessive-Compulsive Disorder: Report of 2 Preliminary Cases
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作者 Sergio A. Sacchettoni Rafael Galera +11 位作者 Juan F. Del Corral Juan P. Abud Aníbal Pinero Luis Teneud Napoleón Torres Rafael Rojas Pedro Rada Félix Guerrero Edgar González Mónica Bifano Dely Yazawa Luis Hernández 《Open Journal of Modern Neurosurgery》 2020年第3期371-381,共11页
Neurosurgery for psychiatric disorders, notably for obsessive-compulsive disorder (OCD), was initiated in Venezuela in the decade of 1970, and consisted since that time in the classic stereotactic anterior cingulotomy... Neurosurgery for psychiatric disorders, notably for obsessive-compulsive disorder (OCD), was initiated in Venezuela in the decade of 1970, and consisted since that time in the classic stereotactic anterior cingulotomy. In order to know further about the physiopathology of this disorder, we performed intracerebral microdialysis in 2 patients who were operated on. The aim was to measure changes in extracellular neurotransmitters within the basal ganglia. The microdialysis probes were stereotactically placed in the right caudate nucleus and in the dorsomedial nucleus of the right thalamus. The microdialysis was done before the left cingulotomy, during the pause and after the right cingulotomy. Glutamate and gamma-aminobutyric acid (GABA) changes were similar in the caudate nucleus of both patients, whereas in the dorsomedial nucleus the changes were opposite among the 2 patients. Although this study does not bring enough data to explain such differences yet, the existence of dynamic changes in the neurochemistry of the basal ganglia during cingulotomy shows that intracerebral microdialysis can help in the understanding of the pathophysiology of OCD and eventually in the design of new surgeries with better results. 展开更多
关键词 Psychiatric neurosurgery PSYCHOSURGERY Obsessive-Compulsive Disorder Intracerebral Microdialysis
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NEUROSURGERY
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《外科研究与新技术》 1997年第4期230-233,共4页
关键词 BRAINSTEM GRANULOMA ADENOMA manifestation suffered NAUSEA epilepsy neurosurgery SEIZURE glioma
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NEUROSURGERY
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《外科研究与新技术》 1994年第1期32-42,共11页
关键词 graft BRAINSTEM ANEURYSM bilateral drainage EVOKED EDEMA neurosurgery suffered STENOSIS
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