A new non-invasive blood glucose measuring apparatus (NBGMA) made up of MSP430F149 SCM (single chip micyoco) was developed,which can measure blood glucose level (BGL) frequently,conveniently and painlessly. The hardwa...A new non-invasive blood glucose measuring apparatus (NBGMA) made up of MSP430F149 SCM (single chip micyoco) was developed,which can measure blood glucose level (BGL) frequently,conveniently and painlessly. The hardware and software of this apparatus were designed,and detecting algorithms based on conservation of energy method (COEM) were presented. According to the law of conservation of energy that the energy derived by human body equals energy consumed by metabolism,and the relationship between convection,evaporation,radiation and the BGL was established. The sensor module was designed. 20 healthy volunteers were involved in the clinical experiment. The BGL measured by an automatic biochemical analyzer (ABA) was set as the reference. Regression analysis was performed to compare the conservation of energy method with the biochemical method,using the 20 data points with blood glucose concentrations ranging from 680 to 1 100 mg/L. Reproducibility was measured for healthy fasting volunteers. The results show that the means of BGL detected by NBGMA and ANA are very close to each other,and the difference of standard deviation (SD) is 24.7 mg/L. The correlative coefficient is 0.807. The coefficient of variation (CV) is 4% at 921.6 mg/L. The resultant regression is evaluated by the Clarke error grid analysis (EGA) and all data points are included in the clinically acceptable regions (region A:100%,region B:0%). Accordingly,it is feasible to measure BGL with COEM.展开更多
目的:探究问题导引-目标链接式护理干预对糖尿病患者低血糖发生率的影响。方法:选择2022年2月—2023年1月泰州市第三人民医院收治的86例糖尿病患者为研究对象,采用计算机法以01~086对患者进行编号,设置01~043患者为对照组(n=43),实施常...目的:探究问题导引-目标链接式护理干预对糖尿病患者低血糖发生率的影响。方法:选择2022年2月—2023年1月泰州市第三人民医院收治的86例糖尿病患者为研究对象,采用计算机法以01~086对患者进行编号,设置01~043患者为对照组(n=43),实施常规护理,设置044~086患者为观察组(n=43),实施问题导引-目标链接式护理干预。比较两组血糖水平、糖尿病自我管理行为及低血糖发生率。结果:护理前,两组血糖水平比较,差异无统计学意义(P>0.05);护理后,两组空腹血糖(FBG)、餐后2 h血糖(2 h PBG)及糖化血红蛋白(HbA1c)水平均下降,观察组低于对照组,差异有统计学意义(P<0.05)。护理前,两组糖尿病患者自我管理行为量表(SDSCA)评分比较,差异无统计学意义(P>0.05);护理14 d后,两组SDSCA评分升高,观察组高于对照组,差异有统计学意义(P<0.05);观察组低血糖发生率低于对照组,差异有统计学意义(P<0.05)。结论:在糖尿病患者的护理中采用问题导引-目标链接式护理干预,能有效控制血糖水平,提升患者自护能力,降低低血糖发生率。展开更多
Electrochemical methods have been widely used in the chemical and pharmaceutical industries,which require accurate concentration measurements,chemical reaction detections and analyses.The electrochemical potentiostat,...Electrochemical methods have been widely used in the chemical and pharmaceutical industries,which require accurate concentration measurements,chemical reaction detections and analyses.The electrochemical potentiostat,the core element in electrochemical instruments,have been discussed as a hot topic addressing the difficulty of applying high-precision constant voltage and picoampere current measurements.Meanwhile,reliable potentiostats are in demand for complicated industrial environments with noises as well as requirements of remotemonitors.This paper describes a potentiostat for industrial glucose measurement that is not only accurate but also fault tolerant to guarantee high reliability in industrial environments.The instrument uses standard industrial communication protocols,profibus,and a 4-20 mA current loop,for remote control and monitoring.Experimental results show that this design has 0.01% accuracy with 1 mV resolution for voltage applications and 0.01% accuracy with 1 pA resolution for current measurements.The design is also shown to be highly reliable in noisy environments.展开更多
无创血糖监测不仅可以减少患者的痛苦 ,还能进行连续测量 ,从而降低并发症的发生 ,它是一种不需收集血样进行体内血糖浓度测量的新技术。本文根据朗伯—比尔定律 (The L ambert- Beer L aw)原理 ,为克服无创血糖检测研究中的难点和缺陷 ...无创血糖监测不仅可以减少患者的痛苦 ,还能进行连续测量 ,从而降低并发症的发生 ,它是一种不需收集血样进行体内血糖浓度测量的新技术。本文根据朗伯—比尔定律 (The L ambert- Beer L aw)原理 ,为克服无创血糖检测研究中的难点和缺陷 ,详细分析了血糖红外光谱的吸收特性 ,利用阵列技术设计了红外多波长无创血糖检测传感器阵列模型 ,对关键技术进行了讨论。用 ME算法建立了信号检测和标定数学模型 ,结合了人体各种影响因素 ,使红外无创血糖检测的精度和稳定性得到了改善。列举了详细的实验实施步骤 ,同时叙述了系统调试的详细过程 。展开更多
基金Project(07JJ6133) supported by the Natural Science Foundation of Hunan Province, China
文摘A new non-invasive blood glucose measuring apparatus (NBGMA) made up of MSP430F149 SCM (single chip micyoco) was developed,which can measure blood glucose level (BGL) frequently,conveniently and painlessly. The hardware and software of this apparatus were designed,and detecting algorithms based on conservation of energy method (COEM) were presented. According to the law of conservation of energy that the energy derived by human body equals energy consumed by metabolism,and the relationship between convection,evaporation,radiation and the BGL was established. The sensor module was designed. 20 healthy volunteers were involved in the clinical experiment. The BGL measured by an automatic biochemical analyzer (ABA) was set as the reference. Regression analysis was performed to compare the conservation of energy method with the biochemical method,using the 20 data points with blood glucose concentrations ranging from 680 to 1 100 mg/L. Reproducibility was measured for healthy fasting volunteers. The results show that the means of BGL detected by NBGMA and ANA are very close to each other,and the difference of standard deviation (SD) is 24.7 mg/L. The correlative coefficient is 0.807. The coefficient of variation (CV) is 4% at 921.6 mg/L. The resultant regression is evaluated by the Clarke error grid analysis (EGA) and all data points are included in the clinically acceptable regions (region A:100%,region B:0%). Accordingly,it is feasible to measure BGL with COEM.
文摘目的:探究问题导引-目标链接式护理干预对糖尿病患者低血糖发生率的影响。方法:选择2022年2月—2023年1月泰州市第三人民医院收治的86例糖尿病患者为研究对象,采用计算机法以01~086对患者进行编号,设置01~043患者为对照组(n=43),实施常规护理,设置044~086患者为观察组(n=43),实施问题导引-目标链接式护理干预。比较两组血糖水平、糖尿病自我管理行为及低血糖发生率。结果:护理前,两组血糖水平比较,差异无统计学意义(P>0.05);护理后,两组空腹血糖(FBG)、餐后2 h血糖(2 h PBG)及糖化血红蛋白(HbA1c)水平均下降,观察组低于对照组,差异有统计学意义(P<0.05)。护理前,两组糖尿病患者自我管理行为量表(SDSCA)评分比较,差异无统计学意义(P>0.05);护理14 d后,两组SDSCA评分升高,观察组高于对照组,差异有统计学意义(P<0.05);观察组低血糖发生率低于对照组,差异有统计学意义(P<0.05)。结论:在糖尿病患者的护理中采用问题导引-目标链接式护理干预,能有效控制血糖水平,提升患者自护能力,降低低血糖发生率。
文摘Electrochemical methods have been widely used in the chemical and pharmaceutical industries,which require accurate concentration measurements,chemical reaction detections and analyses.The electrochemical potentiostat,the core element in electrochemical instruments,have been discussed as a hot topic addressing the difficulty of applying high-precision constant voltage and picoampere current measurements.Meanwhile,reliable potentiostats are in demand for complicated industrial environments with noises as well as requirements of remotemonitors.This paper describes a potentiostat for industrial glucose measurement that is not only accurate but also fault tolerant to guarantee high reliability in industrial environments.The instrument uses standard industrial communication protocols,profibus,and a 4-20 mA current loop,for remote control and monitoring.Experimental results show that this design has 0.01% accuracy with 1 mV resolution for voltage applications and 0.01% accuracy with 1 pA resolution for current measurements.The design is also shown to be highly reliable in noisy environments.
