The cross-shore variation in wind speeds influenced by beach nourishment,especially the dramatic changes at the nourished berm,is important for understanding the aeolian sand transport processes that occur after beach...The cross-shore variation in wind speeds influenced by beach nourishment,especially the dramatic changes at the nourished berm,is important for understanding the aeolian sand transport processes that occur after beach nourishment,which will contribute to better beach nourishment project design on windy coasts.In this paper,the influencing factors and potential mechanism of wind speed variation at the edge of a nourished berm were studied.Field observations,together with the Duna model,were used to study the cross-shore wind speed distribution for different nourishment schemes.The results show that the nourished berm elevation and beachface slope are the main factors controlling the increase in wind speed at the berm edge.When the upper beach slope is constant,the wind speed at the berm edge has a positive linear correlation with the berm elevation.When the berm elevation remains constant,the wind speed at the berm edge is also proportional to the upper beach slope.Considering the coupling effects of nourished berm elevation and beachface slope,a model for predicting the wind speed amplification rate at the nourished berm edge was established,and the underlying coupling mechanism was illustrated.展开更多
To explore the nourishment effect and disaster reduction efficiency of a fully dissipative dry beach under the impact of storms,this paper uses the measured topography and hydrodynamic data to establish a one-dimensio...To explore the nourishment effect and disaster reduction efficiency of a fully dissipative dry beach under the impact of storms,this paper uses the measured topography and hydrodynamic data to establish a one-dimensional numerical model of the XBeach beach profile.By numerically modeling the change in the nourished profile for different dry beach widths under normal waves and storm conditions and the recovery process of the profile after the storm,the degree of response in dry beach nourishment for the fully dissipative beach is analyzed.The results show that under normal wave conditions,the response of the nourished dry beach is obvious.Sediment on the dry beach erodes heavily,and the shoreline moves landward over a long distance.With the increase in the width and size of the dry beach,the wave height at the bottom of the backshore profile decreases,the wave height attenuation rate increases continuously,and the wave elimination effect is remarkable.When the storm incident wave intensifies,the wave height attenuation rate of the nourished dry beach decreases,indicating that the smaller the storm intensity is,the more significant the wave reduction effect of the nourished dry beach is.At the same time,different profile arrangements of nourished dry beaches suffer from different degrees of erosion under storm conditions,with significant changes in profile morphology.With intensified storm action,the intensity of sediment erosion in the nourished dry beach increases,the nourishment is weakened,and the recovery effect of the profile after the storm is not obvious.The results of the numerical modeling highlight that the dry beach nourishment method can resist storms to a certain extent,but the overall effect is relatively limited.展开更多
Medicine,especially traditional Chinese medicine,is by no means a single level of knowledge system and operational skills,blit is frill of humanistic color,encompassing natural science and social science,medical theor...Medicine,especially traditional Chinese medicine,is by no means a single level of knowledge system and operational skills,blit is frill of humanistic color,encompassing natural science and social science,medical theory and traditional culture.Traditional Chinese medicine is rooted in the splendid traditional culture of China,and its theoretical exploration methods and explanations are based on the historical and colorful traditional Chinese culture.This article will give advice on the irrigation and nourishment of traditional culture.展开更多
In recent years, owing to global warming and the rising sea levels, beach nourishment and groin building have been increasingly employed to protect coastal land from shoreline erosion. These actions may degrade beach ...In recent years, owing to global warming and the rising sea levels, beach nourishment and groin building have been increasingly employed to protect coastal land from shoreline erosion. These actions may degrade beach habitats and reduce biomass and invertebrate density at sites where they were employed. We conducted an eco-environmental evaluation at the Anping artificial beach-nourishment project area. At this site, sand piles within a semi-enclosed spur groin have been enforced by use of eco-engineering concepts since 2003. Four sampling sites were monitored during the study period from July 2002 to September 2008. The environmental impact assessment and biological investigations that we conducted are presented here. The results from this study indicate that both biotic （number of species, number of individual organisms, and Shannon-Wiener diversity） and abiotic parameters （suspended solids, biological oxygen demand, chemical oxygen demand, dissolved inorganic nitrogen, dissolved inorganic phosphorus, total phosphorus, total organic carbon, median diameter, and water content） showed significant differences before and after beach engineering construction. Biological conditions became worse in the beginning stages of the engineering but improved after the restoration work completion. This study reveals that the composition of benthic invertebrates changed over the study period, and two groups of organisms, Bivalvia and Gastropoda, seemed to be particularly suitable to this habitat after the semi-enclosed artificial structures completion.展开更多
“Daoyin Benjing”(Art of Nourishing Life)discusses the kidney meridian in depth.It is a dense and heterogeneous text that is heavily influenced by Daoism.The text proposes rules for the maintenance of life using lang...“Daoyin Benjing”(Art of Nourishing Life)discusses the kidney meridian in depth.It is a dense and heterogeneous text that is heavily influenced by Daoism.The text proposes rules for the maintenance of life using language that is often cryptic and under-standable only to the initiated.This language is closely interwoven with the classical terms of traditional Chinese medicine.The kidney is the home of vital energy,which is a type of sexual energy and the root of life.Engagement in moderate sexual activity nourishes life and leads to a long life.This is the goal of every Daoist follower and the goal of every doctor.展开更多
Objective： To evaluate whether herbs of supplementing Qi and nourishing Yin combined with chemotherapy （versus chemotherapy alone） improve survival, increase tumor response, improve performance status or reduce ch...Objective： To evaluate whether herbs of supplementing Qi and nourishing Yin combined with chemotherapy （versus chemotherapy alone） improve survival, increase tumor response, improve performance status or reduce chemotherapy toxicity in patients with lung cancer. Methods： Searching the randomized controlled trials （RCT） studies from the databases （China HowNet database, Wan Fang database, VIP database, Master Thesis and Pubmed） between January 2013 and January 2017. RevMan 5.3 software was used to evaluate the quality of these collected papers. Results： Of 48 potentially relevant publications, 10 randomized studies representing 691 patients met inclusion criteria with 369 cases in the supplementing Qi and nourishing Yin plus Chemotherapy group （Herbs ＋ Chem group） and 322 cases in Chemotherapy group （Chem only group）. There were significant differences between Herbs ＋ Chem group and Chem only group in improving the treatment efficacy and reducing the side effects of chemotherapy （P 〈 0.001 for all）. There were also significant differences between the two groups in tumor response and quality of life （P 〈 0.001 for all）. Conclusion： Herbs of supplementing Qi and nourishing Yin may increase chemotherapy effectiveness, reduce chemotherapy toxicity and improve the quality of life of patients with lung cancer when combined with chemotherapy.展开更多
GABAergic input to Gonadotropin-releasing hormone (GnRH) neurons is necessary to initiate the onset of puberty and its action mainly depends on GABAA receptor of which the subunit composition, properties and consequen...GABAergic input to Gonadotropin-releasing hormone (GnRH) neurons is necessary to initiate the onset of puberty and its action mainly depends on GABAA receptor of which the subunit composition, properties and consequently function varies during this period. Nourishing “Yin”-Removing “Fire” Chinese herb mixture, a Chinese herb-based formulation, has been proved that it may retard the initiation of pubertal development in female precocious puberty rats. Our objective is to investigate the effects of Nourishing “Yin”-Removing “Fire” Chinese herb mixture on the expression of GABAA receptor α subunits in hypothalamus. Female Sprague-Dawley rats were divided into normal (N), precocious puberty model (M) induced by danazol, model exposed to saline (MS) and model exposed to Chinese herb mixture (CHM) groups. All rats were administered by the Chinese herb mixture from P15 on. Coefficients of reproductive organs and serum gonadotropins and estradiol levels in M were significantly enhanced while they were significantly decreased in CHM. The hypothalamic GnRH mRNA was also significantly increased in M and in CHM, as well as ERα mRNA. At the mean time, the hypothalamic GABAA receptor α1 and α3 subunits mRNA were more significantly decreased in M than those of N, while they were more significantly enhanced in CHM than those in M (p 0.01), the protein expression of which in hypothalamus had the same trend as the mRNA expression. The evidence suggests that Nourishing “Yin”-Removing “Fire” Chinese herb mixture could significantly retard the sexual development of the precocious rats, and up-regulate the expressions of hypothalamic GABAA receptor α1 and α3 subunits. Our result indicated that GABAA receptor α1 and α3 subunits might involve in the effective treatment of herb mixture on idiopathic precocious puberty.展开更多
Zhu Zhenheng (courtesy name:Zhu Yanxiu,1281-1358) was from Yiwu County,Zhejiang Province.His family lived near a river named Dan Xi for many generations,hence his sobriquet Old Man Dan Xi,or Mr Dan Xi.Since he was int...Zhu Zhenheng (courtesy name:Zhu Yanxiu,1281-1358) was from Yiwu County,Zhejiang Province.His family lived near a river named Dan Xi for many generations,hence his sobriquet Old Man Dan Xi,or Mr Dan Xi.Since he was intelligent,diligent and eager to learn,he traveled around to visit literary celebrities with the expectation to pass the imperial examination and seek an official position.When he was 36 years old,he heard that Xu Qian,a famous scholar of the Neo-Confucianism came to give lectures in Dongyang County,Zhejiang Province,he soon rushed there to learn from him.1 He kept on study for years and made great progress.But he suffered a reversal of fortune and failed the imperial examinations.At this moment,Xu Qian was badly ill and completely bedridden.One day,when Zhu went to visit him,he said:'I have been ill for a long time,and only those who are skillful in medicine can save me.展开更多
OBJECTIVE: To explore the efficacy and safety of the decoction of nourishing marrow and raising energy in terms of Traditional Chinese Medicine(TCM) in patients with vascular dementia.METHODS: Totally 86 patients with...OBJECTIVE: To explore the efficacy and safety of the decoction of nourishing marrow and raising energy in terms of Traditional Chinese Medicine(TCM) in patients with vascular dementia.METHODS: Totally 86 patients with vascular dementia patients hospitalized from September 2010 to January 2015 were recruited and randomly divided into two groups: control group and observation group. Patients in control group received the conventional treatment, whereas patients in another group were treated with the therapy of nourishing marrow and raising energy according to the theory of TCM. Blesse dementia scale scores were measured before and after the treatment for both groups and adverse effect was documented as well.RESULTS: After treatment, Blesse dementia scale scores reduced in both groups, and the difference in score reduction between the two groups was significant(P<0.05). The rate of adverse events was significantly lower in observation group than in control group(P<0.05).CONCLUSION: Our results demonstrate that the decoction of nourishing marrow and raising energy was an effective and safe alternative to vascular dementia in human subjects.展开更多
The pathogenesis of malignant tumors is the deficiency of vital Qi and the excess of pathogenic Qi.Its basic treating principle is to strengthen vital Qi to eliminate pathogenic factor.The paper is to summarize the cl...The pathogenesis of malignant tumors is the deficiency of vital Qi and the excess of pathogenic Qi.Its basic treating principle is to strengthen vital Qi to eliminate pathogenic factor.The paper is to summarize the clinical experiences in tumor treatment of Dr.Chen Shizhou,a well-known traditional Chinese medicine expert in Weifang City,Shandong Province.He put forward the treatment method of"replenishing Qi and nourishing blood,detoxicating and resolving masses",paying attention to protecting stomach qi and advocating survival with tumor,with remarkable clinical effects.展开更多
[Objective] The aim was to identify the nourishing compositions of Fagopyrum tataricum and screen high-quality buckwheat materials.[Method]A total of 10 species of buckwheat including T32,T31,T30,T14,T28,T23,T24,Jiuji...[Objective] The aim was to identify the nourishing compositions of Fagopyrum tataricum and screen high-quality buckwheat materials.[Method]A total of 10 species of buckwheat including T32,T31,T30,T14,T28,T23,T24,Jiujiang Buckwheat,Weiku 2 and WK-1 were employed as experimental materials,and the contents of the nutritional components（including total sugar,reducing sugar,starch,amylose,amylopectin and protein）,flavonoids content,physical and chemical characteristics（such as expansive force,water holding capacity）of them were respectively measured.[Result]There were significant differences in contents of soluble protein,total sugar,reduced sugar,amylase and expansive force among the cultivars,but the differences in contents of total starch,amylopectin,flavonoids content and water holding capacity were not significant.[Conclusion]The starch content in seeds of buckwheat was relatively high,and amylopectin was the main composition.展开更多
Conch Island is a typical artificial island at the Tanghe Estuary in Bohai Sea,China.To improve natural environment and boost local tourism,beach nourishment will be applied to its north-western shore.The projected be...Conch Island is a typical artificial island at the Tanghe Estuary in Bohai Sea,China.To improve natural environment and boost local tourism,beach nourishment will be applied to its north-western shore.The projected beach is landward and opposite to the Jinmeng Bay Beach.Nowadays,with climate changes,frequent heavy rainfalls in Hebei Province rise flood hazards at the Tanghe Estuary.Under this circumstance,potential influences on the projected beach of a flood are investigated for sustainable managements.A multi-coupled model is established and based on the data from field observations,where wave model,flow model and multifraction sediment transport model are included.In addition,the impacts on the projected beach of different components in extreme events are discussed,including the spring tides,storm winds,storm waves,and sediment inputs.The numerical results indicate the following result.(1)Artificial islands protect the coasts from erosion by obstructing landward waves,but rise the deposition risks along the target shore.(2)Flood brings massive sediment inputs and leads to scours at the estuary,but the currents with high sediment concentration contribute to the accretions along the target shore.(3)The projected beach mitigates flood actions and reduces the maximum mean sediment concentration along the target shore by 20%.(4)The storm winds restrict the flood and decrease the maximum mean sediment concentration by 21%.With the combined actions of storm winds and waves,the maximum value further declines by 38%.(5)A quadratic polynomial relationship between the deposition depths and the maximum sediment inputs with flood is established for estimations on the potential morphological changes after the flood process in extreme events.For the uncertainty of estuarine floods,continuous monitoring on local hydrodynamic variations and sediment characteristics at Tanghe Estuary is necessary.展开更多
AIM： TO observe the therapeutic effects of new traditional Chinese medicine （TClVl） therapy on coagulation disorder and accompanying intractable jaundice in HBV-related liver cirrhosis patients. METHODS： Using str...AIM： TO observe the therapeutic effects of new traditional Chinese medicine （TClVl） therapy on coagulation disorder and accompanying intractable jaundice in HBV-related liver cirrhosis patients. METHODS： Using stratified random sampling according to fibrinogen （Fib） levels, 145 liver cirrhosis patients due to hepatitis B complicated by coagulation disorder were treated. Of them, 70 in research group were treated with TCM by ＂nourishing yin, cooling blood and invigorating blood circulation＂ and Western medicine, 75 in control group were treated with conventional Western medicine. The indexes of liver function, coagulation function and bleeding events were observed and compared. RESULTS： The prothrombin time （PT） was shorter and the fibrinogen （Fib） level was higher in the research group than in the control group （Fib = 1.6-2.0 g/L, 1.1-1.5 g/L, and ≤ 1.0 g/L）. The total bilirubin （TBIL） level was significantly lower in the research group than in the control group, except for the subgroup of FIB ≤ 1.0 g/L. CONCLUSION： TCM therapy can improve coagulation fuction and decrease TBIL.展开更多
Objective: To explore the possibility of using traditional Chinese medicine (TCM) in treating β thalassemia, its clinical effect and molecular mechanism of the action.Methods: According to the TCM theory of“Shen pro...Objective: To explore the possibility of using traditional Chinese medicine (TCM) in treating β thalassemia, its clinical effect and molecular mechanism of the action.Methods: According to the TCM theory of“Shen producing marrow”, the composite recipe, Yisui Shenxueling Granule (YSSXL), consisting of Chinese drugs for nourishing Shen and supplementing marrow (NS&SM) was given orally to 7 8 patients with β thalassemia (49 of the severe type and 29 of moderate type ), 3 times a day, 10 g each time (for children, the dose would be reduced proper ly), with 3 months as one therapeutic course, and no blood transfusion used in t he course. The clinical therapeutic efficacy and hematologic parameters in patie nts were observed, and systemic gene analysis was conducted with PAGE, PCR, PCR SSCP, RT PCR and DNA sequences analysis and mRNA detection, in order to s tudy the molecular mechanism from the relationships between genetic mutation and clinical efficacy, gene expression and its regulation. Results: YSSXL showed obvious therapeutic effect in treating β thalassemia. Gene analysis revealed that it did not change the genetic mutatio n type, but could obviously increase hemoglobin, fetal hemoglobin (HbF), γ/(β+ γ) globin ratio, γ globin mRNA expression and GM CSF mRNA expression in patients, as well as the GM CSFmRMA in marrow of mice after 60 Co radia tion. Conclusion: YSSXL has a remarkable therapeutic effect on β tha lassemia, and its possible mechanism is its action in unlocking γ gene, in creasing the γ globin expression and enhancing HbF synthesis so as to compe nsate for the gene defect. This study has opened a new path for the treatment of β thalassemia with TCM.展开更多
By use of a shorehne-change numerical model （GENESIS） based on one-line theory, a preliminary modeling study on shoreline changes caused by a beach nourishment project in Beidaihe, China, is presented in this paper....By use of a shorehne-change numerical model （GENESIS） based on one-line theory, a preliminary modeling study on shoreline changes caused by a beach nourishment project in Beidaihe, China, is presented in this paper. Firstly, the GENESIS model is verified and model sensitivity to the major parameter changes is discussed by simulating a hydraulic model test. The beach nourishment project, after that the shoreline change is kept being monitored, is a small-scale emergency one carried out to use two bathing places on the west beach in the summer, 2008. In this paper the shoreline changes caused by the beach nourishment project are modeled by the GENESIS model, and the computed results fit well with the measured shorelines. With the same model and parameters, a long-term performance of the project is predicted, and the result shows that the bathing places only can be suitable for bathing in 2 to 3 years without subsequence nourishment project. Therefore, it is proposed to nourish the beaches in time to keep the service life of the beach in recent years and carry out the beach nourishment project for the whole west beach as soon as possible.展开更多
Presents the effect of enhanced coagulation with a composite chemical containing ferrate upon algae removal with results showing that enhanced coagulation is efficient for algae removal. A comparison made between enha...Presents the effect of enhanced coagulation with a composite chemical containing ferrate upon algae removal with results showing that enhanced coagulation is efficient for algae removal. A comparison made between enhanced coagulation with composite ferrate and conventional pre chlorination, indicates that algae removal efficiency of the former was higher than that of the latter. And the algae removal efficiency can be further improved by extending the time of enhanced coagulation with the composite chemical containing ferrate.展开更多
In this article, capacities and freedom approach, as well as lifestyles are explored taking into account child nutrition, and other relevant dimensions of human life more than just economic and other elementary resour...In this article, capacities and freedom approach, as well as lifestyles are explored taking into account child nutrition, and other relevant dimensions of human life more than just economic and other elementary resources, and also social, cultural, psychological, values and freedom dimensions. Nourishment, health and survival are considered some of the elementary capabilities, and the concept of malnutrition, including under and over-nutrition, is discussed, based upon the comparison of data on food production and distribution from the macro level context, as well as from the family and individual levels included anthropometrical measurements. The advantages and limits of different kinds of measurements are discussed, suggesting more complex approaches, based also upon family and gender equality. The double burden of malnutrition, under and over-nourishment of children is highlighted as a public health issue to be resolved by adequate policies and considering the role of female empowerment, nutrition-knowledge and education as relevant keys to achieve equality in family food and resource distribution, healthy lifestyles and human development.展开更多
Composition and utilization of nutria fat were studied in this paper.The results indicated that there were much amount of linoleic acid-necessary for human being and abundant fat-soluble vitamins VA,VE and VK.Nutria o...Composition and utilization of nutria fat were studied in this paper.The results indicated that there were much amount of linoleic acid-necessary for human being and abundant fat-soluble vitamins VA,VE and VK.Nutria oil is tasteless, clear transparent and stable. The nourishing cream made from it had good cold or heat- resistance properties and it is a perfect natural cosmetics.展开更多
Objective:To A randomized controlled trial(RCTS)of lung tonifying and kidney tonifying in the treatment of chronic obstructive pulmonary disease(copd)by meta-analysis.Methods:Computer retrieval of databases such as C...Objective:To A randomized controlled trial(RCTS)of lung tonifying and kidney tonifying in the treatment of chronic obstructive pulmonary disease(copd)by meta-analysis.Methods:Computer retrieval of databases such as CNKI、VIP、WanFang、Cochrane Library、EMbase、PubMed.The retrieval time was from the database construction to March 2020,and two evaluators were selected to screen the documents according to the na sorting standards,extract the data with Excel 2010 software,and perform Meta analysis with Rev Man5.3 software.Results:21 RCTS were included.Meta-analysis results show that compared with the conventional treatment,the method of supplementing lung and tonifying kidney can obviously improve lung function(MD=1.69,95%CI[1.36,2.01],P<0.00001)、reduce TCM syndrome score(MD=39.83,95%CI[18.10,61.56],P=0.0003)、improve life quality(MD=-5.90,95%CI[-8.95,-2.85],P=0.0001)、regulates serum immunoglobulin(MD=0.37,95%CI[0.31,0.44],P<0.00001)、improve 6MWD(MD=39.83,95%CI[18.10,61.56],P=0.0003)、improve CAT(MD=-1.68,95%CI[-2.05,-1.30],P<0.00001).The differences were statistically significant.For improved T lymphocyte subsets(MD=0.96,95%CI[-0.10,2.03],P=0.08)not statistically significant.Conclusion:Lung-tonifying kidney-tonifying method had better efficacy in improving lung function,reducing TCM syndrome score,improving quality of life,improving immunoglobulin,improving 6WMD,improving CAT,but the efficacy in improving t-lymphocyte subgroup was similar to that in the control group.Due to the limited quantity and quality of samples included in this paper,more multicenter randomized controlled trials with rigorous design of large samples should be carried out for verification.展开更多
Potential sandy coast erosion and socio-economic impacts under sea level rise scenarios as well as socio-economic pathways were assessed in Liaodong Bay.Results show that sea level is projected to rise by 20-43 cm in ...Potential sandy coast erosion and socio-economic impacts under sea level rise scenarios as well as socio-economic pathways were assessed in Liaodong Bay.Results show that sea level is projected to rise by 20-43 cm in Liaodong Bay by 2100.And dry land loss increases in all sea level rise scenarios,with the maximum loss of 32.1 km2 in 2100 under RCP8.5.Coastal erosion results in forced migration,and the forced migration is higher under SSP3 than other pathways due to its higher population growth rate,reaching the highest of 3.1×10^4 under SSP3/RCP8.5 in 2100.Moreover,the differences of forced migration among all scenarios increas after 2050,and the migration increasing rates tend to decrease under RCP2.6 and RCP4.5.The maximum economic loss due to coastal erosion will reach 8.05 billion yuan under SSP5/RCP8.5 in 2100,in which land loss cost is two order less than migration cost,and the share of total erosion-induced economic loss in local GDP varies from 1.12‰ to 4.76‰ under all scenarios,which is an important indicator to draw local government's attention to take measures such as beach nourishment,especially for tourist beaches.Optimally,it is recommended by cost-benefit analysis to carry out nourishment mainly on beaches with high value,while there is no need for nourishment in areas where erosion impacts are negligible.展开更多
基金The National Natural Science Foundation of China under contract Nos 42076211 and 41930538.
文摘The cross-shore variation in wind speeds influenced by beach nourishment,especially the dramatic changes at the nourished berm,is important for understanding the aeolian sand transport processes that occur after beach nourishment,which will contribute to better beach nourishment project design on windy coasts.In this paper,the influencing factors and potential mechanism of wind speed variation at the edge of a nourished berm were studied.Field observations,together with the Duna model,were used to study the cross-shore wind speed distribution for different nourishment schemes.The results show that the nourished berm elevation and beachface slope are the main factors controlling the increase in wind speed at the berm edge.When the upper beach slope is constant,the wind speed at the berm edge has a positive linear correlation with the berm elevation.When the berm elevation remains constant,the wind speed at the berm edge is also proportional to the upper beach slope.Considering the coupling effects of nourished berm elevation and beachface slope,a model for predicting the wind speed amplification rate at the nourished berm edge was established,and the underlying coupling mechanism was illustrated.
基金The National Natural Science Foundation of China under contract No.41930538the Scientific Research Foundation of the Third Institute of Oceanography,Ministry of Natural Resources under contract No.2022017。
文摘To explore the nourishment effect and disaster reduction efficiency of a fully dissipative dry beach under the impact of storms,this paper uses the measured topography and hydrodynamic data to establish a one-dimensional numerical model of the XBeach beach profile.By numerically modeling the change in the nourished profile for different dry beach widths under normal waves and storm conditions and the recovery process of the profile after the storm,the degree of response in dry beach nourishment for the fully dissipative beach is analyzed.The results show that under normal wave conditions,the response of the nourished dry beach is obvious.Sediment on the dry beach erodes heavily,and the shoreline moves landward over a long distance.With the increase in the width and size of the dry beach,the wave height at the bottom of the backshore profile decreases,the wave height attenuation rate increases continuously,and the wave elimination effect is remarkable.When the storm incident wave intensifies,the wave height attenuation rate of the nourished dry beach decreases,indicating that the smaller the storm intensity is,the more significant the wave reduction effect of the nourished dry beach is.At the same time,different profile arrangements of nourished dry beaches suffer from different degrees of erosion under storm conditions,with significant changes in profile morphology.With intensified storm action,the intensity of sediment erosion in the nourished dry beach increases,the nourishment is weakened,and the recovery effect of the profile after the storm is not obvious.The results of the numerical modeling highlight that the dry beach nourishment method can resist storms to a certain extent,but the overall effect is relatively limited.
文摘Medicine,especially traditional Chinese medicine,is by no means a single level of knowledge system and operational skills,blit is frill of humanistic color,encompassing natural science and social science,medical theory and traditional culture.Traditional Chinese medicine is rooted in the splendid traditional culture of China,and its theoretical exploration methods and explanations are based on the historical and colorful traditional Chinese culture.This article will give advice on the irrigation and nourishment of traditional culture.
基金supported by the Science Council under Grant Nos. NSC96-2221-E-009-241-MY3 and NSC 96-2221-E- 216-051
文摘In recent years, owing to global warming and the rising sea levels, beach nourishment and groin building have been increasingly employed to protect coastal land from shoreline erosion. These actions may degrade beach habitats and reduce biomass and invertebrate density at sites where they were employed. We conducted an eco-environmental evaluation at the Anping artificial beach-nourishment project area. At this site, sand piles within a semi-enclosed spur groin have been enforced by use of eco-engineering concepts since 2003. Four sampling sites were monitored during the study period from July 2002 to September 2008. The environmental impact assessment and biological investigations that we conducted are presented here. The results from this study indicate that both biotic （number of species, number of individual organisms, and Shannon-Wiener diversity） and abiotic parameters （suspended solids, biological oxygen demand, chemical oxygen demand, dissolved inorganic nitrogen, dissolved inorganic phosphorus, total phosphorus, total organic carbon, median diameter, and water content） showed significant differences before and after beach engineering construction. Biological conditions became worse in the beginning stages of the engineering but improved after the restoration work completion. This study reveals that the composition of benthic invertebrates changed over the study period, and two groups of organisms, Bivalvia and Gastropoda, seemed to be particularly suitable to this habitat after the semi-enclosed artificial structures completion.
文摘“Daoyin Benjing”(Art of Nourishing Life)discusses the kidney meridian in depth.It is a dense and heterogeneous text that is heavily influenced by Daoism.The text proposes rules for the maintenance of life using language that is often cryptic and under-standable only to the initiated.This language is closely interwoven with the classical terms of traditional Chinese medicine.The kidney is the home of vital energy,which is a type of sexual energy and the root of life.Engagement in moderate sexual activity nourishes life and leads to a long life.This is the goal of every Daoist follower and the goal of every doctor.
文摘Objective： To evaluate whether herbs of supplementing Qi and nourishing Yin combined with chemotherapy （versus chemotherapy alone） improve survival, increase tumor response, improve performance status or reduce chemotherapy toxicity in patients with lung cancer. Methods： Searching the randomized controlled trials （RCT） studies from the databases （China HowNet database, Wan Fang database, VIP database, Master Thesis and Pubmed） between January 2013 and January 2017. RevMan 5.3 software was used to evaluate the quality of these collected papers. Results： Of 48 potentially relevant publications, 10 randomized studies representing 691 patients met inclusion criteria with 369 cases in the supplementing Qi and nourishing Yin plus Chemotherapy group （Herbs ＋ Chem group） and 322 cases in Chemotherapy group （Chem only group）. There were significant differences between Herbs ＋ Chem group and Chem only group in improving the treatment efficacy and reducing the side effects of chemotherapy （P 〈 0.001 for all）. There were also significant differences between the two groups in tumor response and quality of life （P 〈 0.001 for all）. Conclusion： Herbs of supplementing Qi and nourishing Yin may increase chemotherapy effectiveness, reduce chemotherapy toxicity and improve the quality of life of patients with lung cancer when combined with chemotherapy.
文摘GABAergic input to Gonadotropin-releasing hormone (GnRH) neurons is necessary to initiate the onset of puberty and its action mainly depends on GABAA receptor of which the subunit composition, properties and consequently function varies during this period. Nourishing “Yin”-Removing “Fire” Chinese herb mixture, a Chinese herb-based formulation, has been proved that it may retard the initiation of pubertal development in female precocious puberty rats. Our objective is to investigate the effects of Nourishing “Yin”-Removing “Fire” Chinese herb mixture on the expression of GABAA receptor α subunits in hypothalamus. Female Sprague-Dawley rats were divided into normal (N), precocious puberty model (M) induced by danazol, model exposed to saline (MS) and model exposed to Chinese herb mixture (CHM) groups. All rats were administered by the Chinese herb mixture from P15 on. Coefficients of reproductive organs and serum gonadotropins and estradiol levels in M were significantly enhanced while they were significantly decreased in CHM. The hypothalamic GnRH mRNA was also significantly increased in M and in CHM, as well as ERα mRNA. At the mean time, the hypothalamic GABAA receptor α1 and α3 subunits mRNA were more significantly decreased in M than those of N, while they were more significantly enhanced in CHM than those in M (p 0.01), the protein expression of which in hypothalamus had the same trend as the mRNA expression. The evidence suggests that Nourishing “Yin”-Removing “Fire” Chinese herb mixture could significantly retard the sexual development of the precocious rats, and up-regulate the expressions of hypothalamic GABAA receptor α1 and α3 subunits. Our result indicated that GABAA receptor α1 and α3 subunits might involve in the effective treatment of herb mixture on idiopathic precocious puberty.
文摘Zhu Zhenheng (courtesy name:Zhu Yanxiu,1281-1358) was from Yiwu County,Zhejiang Province.His family lived near a river named Dan Xi for many generations,hence his sobriquet Old Man Dan Xi,or Mr Dan Xi.Since he was intelligent,diligent and eager to learn,he traveled around to visit literary celebrities with the expectation to pass the imperial examination and seek an official position.When he was 36 years old,he heard that Xu Qian,a famous scholar of the Neo-Confucianism came to give lectures in Dongyang County,Zhejiang Province,he soon rushed there to learn from him.1 He kept on study for years and made great progress.But he suffered a reversal of fortune and failed the imperial examinations.At this moment,Xu Qian was badly ill and completely bedridden.One day,when Zhu went to visit him,he said:'I have been ill for a long time,and only those who are skillful in medicine can save me.
基金funded by Administration of Traditional Chinese Medicine of Shaanxi Province(Grant No.:200781)
文摘OBJECTIVE: To explore the efficacy and safety of the decoction of nourishing marrow and raising energy in terms of Traditional Chinese Medicine(TCM) in patients with vascular dementia.METHODS: Totally 86 patients with vascular dementia patients hospitalized from September 2010 to January 2015 were recruited and randomly divided into two groups: control group and observation group. Patients in control group received the conventional treatment, whereas patients in another group were treated with the therapy of nourishing marrow and raising energy according to the theory of TCM. Blesse dementia scale scores were measured before and after the treatment for both groups and adverse effect was documented as well.RESULTS: After treatment, Blesse dementia scale scores reduced in both groups, and the difference in score reduction between the two groups was significant(P<0.05). The rate of adverse events was significantly lower in observation group than in control group(P<0.05).CONCLUSION: Our results demonstrate that the decoction of nourishing marrow and raising energy was an effective and safe alternative to vascular dementia in human subjects.
文摘The pathogenesis of malignant tumors is the deficiency of vital Qi and the excess of pathogenic Qi.Its basic treating principle is to strengthen vital Qi to eliminate pathogenic factor.The paper is to summarize the clinical experiences in tumor treatment of Dr.Chen Shizhou,a well-known traditional Chinese medicine expert in Weifang City,Shandong Province.He put forward the treatment method of"replenishing Qi and nourishing blood,detoxicating and resolving masses",paying attention to protecting stomach qi and advocating survival with tumor,with remarkable clinical effects.
基金Supported by Science and Technology Foundation of Guizhou Province([2009]2108)Doctoral Scientific Research Foundation of Guizhou Normal University[2008],Key Program of Student Scientific Research Foundation of Guizhou Normal University[2010]~~
文摘[Objective] The aim was to identify the nourishing compositions of Fagopyrum tataricum and screen high-quality buckwheat materials.[Method]A total of 10 species of buckwheat including T32,T31,T30,T14,T28,T23,T24,Jiujiang Buckwheat,Weiku 2 and WK-1 were employed as experimental materials,and the contents of the nutritional components（including total sugar,reducing sugar,starch,amylose,amylopectin and protein）,flavonoids content,physical and chemical characteristics（such as expansive force,water holding capacity）of them were respectively measured.[Result]There were significant differences in contents of soluble protein,total sugar,reduced sugar,amylase and expansive force among the cultivars,but the differences in contents of total starch,amylopectin,flavonoids content and water holding capacity were not significant.[Conclusion]The starch content in seeds of buckwheat was relatively high,and amylopectin was the main composition.
基金The National Key Research and Development Program of China under contract No.2022YFC3106205the National Natural Science Foundation of China under contract Nos 41976159 and 41776098.
文摘Conch Island is a typical artificial island at the Tanghe Estuary in Bohai Sea,China.To improve natural environment and boost local tourism,beach nourishment will be applied to its north-western shore.The projected beach is landward and opposite to the Jinmeng Bay Beach.Nowadays,with climate changes,frequent heavy rainfalls in Hebei Province rise flood hazards at the Tanghe Estuary.Under this circumstance,potential influences on the projected beach of a flood are investigated for sustainable managements.A multi-coupled model is established and based on the data from field observations,where wave model,flow model and multifraction sediment transport model are included.In addition,the impacts on the projected beach of different components in extreme events are discussed,including the spring tides,storm winds,storm waves,and sediment inputs.The numerical results indicate the following result.(1)Artificial islands protect the coasts from erosion by obstructing landward waves,but rise the deposition risks along the target shore.(2)Flood brings massive sediment inputs and leads to scours at the estuary,but the currents with high sediment concentration contribute to the accretions along the target shore.(3)The projected beach mitigates flood actions and reduces the maximum mean sediment concentration along the target shore by 20%.(4)The storm winds restrict the flood and decrease the maximum mean sediment concentration by 21%.With the combined actions of storm winds and waves,the maximum value further declines by 38%.(5)A quadratic polynomial relationship between the deposition depths and the maximum sediment inputs with flood is established for estimations on the potential morphological changes after the flood process in extreme events.For the uncertainty of estuarine floods,continuous monitoring on local hydrodynamic variations and sediment characteristics at Tanghe Estuary is necessary.
基金Science and Technology Agency of Guangdong Province,NO.2008B030301041
文摘AIM： TO observe the therapeutic effects of new traditional Chinese medicine （TClVl） therapy on coagulation disorder and accompanying intractable jaundice in HBV-related liver cirrhosis patients. METHODS： Using stratified random sampling according to fibrinogen （Fib） levels, 145 liver cirrhosis patients due to hepatitis B complicated by coagulation disorder were treated. Of them, 70 in research group were treated with TCM by ＂nourishing yin, cooling blood and invigorating blood circulation＂ and Western medicine, 75 in control group were treated with conventional Western medicine. The indexes of liver function, coagulation function and bleeding events were observed and compared. RESULTS： The prothrombin time （PT） was shorter and the fibrinogen （Fib） level was higher in the research group than in the control group （Fib = 1.6-2.0 g/L, 1.1-1.5 g/L, and ≤ 1.0 g/L）. The total bilirubin （TBIL） level was significantly lower in the research group than in the control group, except for the subgroup of FIB ≤ 1.0 g/L. CONCLUSION： TCM therapy can improve coagulation fuction and decrease TBIL.
基金This item was supported by National Funds of Natural Sciences (No. 3017119 9) and Natural Science Foundation of Guangxi Autonomous Region (No. 014402C)
文摘Objective: To explore the possibility of using traditional Chinese medicine (TCM) in treating β thalassemia, its clinical effect and molecular mechanism of the action.Methods: According to the TCM theory of“Shen producing marrow”, the composite recipe, Yisui Shenxueling Granule (YSSXL), consisting of Chinese drugs for nourishing Shen and supplementing marrow (NS&SM) was given orally to 7 8 patients with β thalassemia (49 of the severe type and 29 of moderate type ), 3 times a day, 10 g each time (for children, the dose would be reduced proper ly), with 3 months as one therapeutic course, and no blood transfusion used in t he course. The clinical therapeutic efficacy and hematologic parameters in patie nts were observed, and systemic gene analysis was conducted with PAGE, PCR, PCR SSCP, RT PCR and DNA sequences analysis and mRNA detection, in order to s tudy the molecular mechanism from the relationships between genetic mutation and clinical efficacy, gene expression and its regulation. Results: YSSXL showed obvious therapeutic effect in treating β thalassemia. Gene analysis revealed that it did not change the genetic mutatio n type, but could obviously increase hemoglobin, fetal hemoglobin (HbF), γ/(β+ γ) globin ratio, γ globin mRNA expression and GM CSF mRNA expression in patients, as well as the GM CSFmRMA in marrow of mice after 60 Co radia tion. Conclusion: YSSXL has a remarkable therapeutic effect on β tha lassemia, and its possible mechanism is its action in unlocking γ gene, in creasing the γ globin expression and enhancing HbF synthesis so as to compe nsate for the gene defect. This study has opened a new path for the treatment of β thalassemia with TCM.
基金supported by two funds from the Department of Land and Resources of Hebei Province,China(Grant Nos.HEBEIGT2006ZT and HEBEIGT2008-2903)two grants from the Ministry of Science and Technology,China(Grant Nos.2008BAJ08B14 and 2007FY110300-03)
文摘By use of a shorehne-change numerical model （GENESIS） based on one-line theory, a preliminary modeling study on shoreline changes caused by a beach nourishment project in Beidaihe, China, is presented in this paper. Firstly, the GENESIS model is verified and model sensitivity to the major parameter changes is discussed by simulating a hydraulic model test. The beach nourishment project, after that the shoreline change is kept being monitored, is a small-scale emergency one carried out to use two bathing places on the west beach in the summer, 2008. In this paper the shoreline changes caused by the beach nourishment project are modeled by the GENESIS model, and the computed results fit well with the measured shorelines. With the same model and parameters, a long-term performance of the project is predicted, and the result shows that the bathing places only can be suitable for bathing in 2 to 3 years without subsequence nourishment project. Therefore, it is proposed to nourish the beaches in time to keep the service life of the beach in recent years and carry out the beach nourishment project for the whole west beach as soon as possible.
文摘Presents the effect of enhanced coagulation with a composite chemical containing ferrate upon algae removal with results showing that enhanced coagulation is efficient for algae removal. A comparison made between enhanced coagulation with composite ferrate and conventional pre chlorination, indicates that algae removal efficiency of the former was higher than that of the latter. And the algae removal efficiency can be further improved by extending the time of enhanced coagulation with the composite chemical containing ferrate.
文摘In this article, capacities and freedom approach, as well as lifestyles are explored taking into account child nutrition, and other relevant dimensions of human life more than just economic and other elementary resources, and also social, cultural, psychological, values and freedom dimensions. Nourishment, health and survival are considered some of the elementary capabilities, and the concept of malnutrition, including under and over-nutrition, is discussed, based upon the comparison of data on food production and distribution from the macro level context, as well as from the family and individual levels included anthropometrical measurements. The advantages and limits of different kinds of measurements are discussed, suggesting more complex approaches, based also upon family and gender equality. The double burden of malnutrition, under and over-nourishment of children is highlighted as a public health issue to be resolved by adequate policies and considering the role of female empowerment, nutrition-knowledge and education as relevant keys to achieve equality in family food and resource distribution, healthy lifestyles and human development.
文摘Composition and utilization of nutria fat were studied in this paper.The results indicated that there were much amount of linoleic acid-necessary for human being and abundant fat-soluble vitamins VA,VE and VK.Nutria oil is tasteless, clear transparent and stable. The nourishing cream made from it had good cold or heat- resistance properties and it is a perfect natural cosmetics.
基金National Natural Science Foundation of China(No.81473564)。
文摘Objective:To A randomized controlled trial(RCTS)of lung tonifying and kidney tonifying in the treatment of chronic obstructive pulmonary disease(copd)by meta-analysis.Methods:Computer retrieval of databases such as CNKI、VIP、WanFang、Cochrane Library、EMbase、PubMed.The retrieval time was from the database construction to March 2020,and two evaluators were selected to screen the documents according to the na sorting standards,extract the data with Excel 2010 software,and perform Meta analysis with Rev Man5.3 software.Results:21 RCTS were included.Meta-analysis results show that compared with the conventional treatment,the method of supplementing lung and tonifying kidney can obviously improve lung function(MD=1.69,95%CI[1.36,2.01],P<0.00001)、reduce TCM syndrome score(MD=39.83,95%CI[18.10,61.56],P=0.0003)、improve life quality(MD=-5.90,95%CI[-8.95,-2.85],P=0.0001)、regulates serum immunoglobulin(MD=0.37,95%CI[0.31,0.44],P<0.00001)、improve 6MWD(MD=39.83,95%CI[18.10,61.56],P=0.0003)、improve CAT(MD=-1.68,95%CI[-2.05,-1.30],P<0.00001).The differences were statistically significant.For improved T lymphocyte subsets(MD=0.96,95%CI[-0.10,2.03],P=0.08)not statistically significant.Conclusion:Lung-tonifying kidney-tonifying method had better efficacy in improving lung function,reducing TCM syndrome score,improving quality of life,improving immunoglobulin,improving 6WMD,improving CAT,but the efficacy in improving t-lymphocyte subgroup was similar to that in the control group.Due to the limited quantity and quality of samples included in this paper,more multicenter randomized controlled trials with rigorous design of large samples should be carried out for verification.
基金supported by the NMDIS Youth Fund Study on the contribution rate of sea level rise to coastal erosion of typical coastal segments(2018).
文摘Potential sandy coast erosion and socio-economic impacts under sea level rise scenarios as well as socio-economic pathways were assessed in Liaodong Bay.Results show that sea level is projected to rise by 20-43 cm in Liaodong Bay by 2100.And dry land loss increases in all sea level rise scenarios,with the maximum loss of 32.1 km2 in 2100 under RCP8.5.Coastal erosion results in forced migration,and the forced migration is higher under SSP3 than other pathways due to its higher population growth rate,reaching the highest of 3.1×10^4 under SSP3/RCP8.5 in 2100.Moreover,the differences of forced migration among all scenarios increas after 2050,and the migration increasing rates tend to decrease under RCP2.6 and RCP4.5.The maximum economic loss due to coastal erosion will reach 8.05 billion yuan under SSP5/RCP8.5 in 2100,in which land loss cost is two order less than migration cost,and the share of total erosion-induced economic loss in local GDP varies from 1.12‰ to 4.76‰ under all scenarios,which is an important indicator to draw local government's attention to take measures such as beach nourishment,especially for tourist beaches.Optimally,it is recommended by cost-benefit analysis to carry out nourishment mainly on beaches with high value,while there is no need for nourishment in areas where erosion impacts are negligible.
