The large-scale multi-objective optimization algorithm(LSMOA),based on the grouping of decision variables,is an advanced method for handling high-dimensional decision variables.However,in practical problems,the intera...The large-scale multi-objective optimization algorithm(LSMOA),based on the grouping of decision variables,is an advanced method for handling high-dimensional decision variables.However,in practical problems,the interaction among decision variables is intricate,leading to large group sizes and suboptimal optimization effects;hence a large-scale multi-objective optimization algorithm based on weighted overlapping grouping of decision variables(MOEAWOD)is proposed in this paper.Initially,the decision variables are perturbed and categorized into convergence and diversity variables;subsequently,the convergence variables are subdivided into groups based on the interactions among different decision variables.If the size of a group surpasses the set threshold,that group undergoes a process of weighting and overlapping grouping.Specifically,the interaction strength is evaluated based on the interaction frequency and number of objectives among various decision variables.The decision variable with the highest interaction in the group is identified and disregarded,and the remaining variables are then reclassified into subgroups.Finally,the decision variable with the strongest interaction is added to each subgroup.MOEAWOD minimizes the interactivity between different groups and maximizes the interactivity of decision variables within groups,which contributed to the optimized direction of convergence and diversity exploration with different groups.MOEAWOD was subjected to testing on 18 benchmark large-scale optimization problems,and the experimental results demonstrate the effectiveness of our methods.Compared with the other algorithms,our method is still at an advantage.展开更多
BACKGROUND Infections by non-tuberculous mycobacteria(NTM)have become more common in recent years.Mycobacterium canariasense(M.canariasense)was first reported as an opportunistic pathogen in 2004,but there have been v...BACKGROUND Infections by non-tuberculous mycobacteria(NTM)have become more common in recent years.Mycobacterium canariasense(M.canariasense)was first reported as an opportunistic pathogen in 2004,but there have been very few case reports since then.Nocardia is a genus of aerobic and Gram-positive bacilli,and these species are also opportunistic pathogens and in the Mycobacteriales order.Conventional methods for diagnosis of NTM are inefficient.Metagenomic next-generation sequencing(mNGS)can rapidly detect many pathogenic microorganisms,even rare species.Most NTM and Nocardia infections occur in immunocompromised patients with atypical clinical symptoms.There are no previous reports of infection by M.canariasense and Nocardia farcinica(N.farcinica),especially in immunocompetent patients.This case report describes an immunocompetent 52-year-old woman who had overlapping infections of M.canariasense,N.farcinica,and Candida parapsilosis(C.parapsilosis)based on mNGS.CASE SUMMARY A 52-year-old woman presented with a productive cough and chest pain for 2 wk,and recurrent episodes of moderate-grade fever for 1 wk.She received antibiotics for 1 wk at a local hospital,and experienced defervescence,but the productive cough and chest pain persisted.We collected samples of a lung lesion and alveolar lavage fluid for mNGS.The lung tissue was positive for M.canariasense,N.farcinica,and C.parapsilosis,and the alveolar lavage fluid was positive for M.canariasense.The diagnosis was pneumonia,and application of appropriate antibiotic therapy cured the patient.CONCLUSION Etiological diagnosis is critical for patients with infectious diseases.mNGS can identify rare and novel pathogens,and does not require a priori knowledge.展开更多
This article discusses the roadbed splicing for hub interchanges.The article starts with a description of the characteristics of junction roadbed splicing.The application of splicing technology is explained using a su...This article discusses the roadbed splicing for hub interchanges.The article starts with a description of the characteristics of junction roadbed splicing.The application of splicing technology is explained using a subgrade splicing scheme of a project.Roadbed splicing involves stepwise excavation and preparative measures like surface cleaning and backfilling.This article serves to provide a valuable reference for road and bridge construction and improve the quality of China’s road and bridge projects,so as to achieve sustainable development of the road and bridge engineering industry.展开更多
This article analyzes the differential settlement of new and old roadbeds after widening and its characteristics based on a highway reconstruction and expansion project case study.The research proposes a subgrade sett...This article analyzes the differential settlement of new and old roadbeds after widening and its characteristics based on a highway reconstruction and expansion project case study.The research proposes a subgrade settlement control standard that states that the maximum differential settlement value should be less than 5 cm when the embankment fill height exceeds 20 m.Similarly,the maximum differential settlement value should be less than 10 cm when the embankment fill height does not exceed 20 m.The findings of the study can provide a useful reference for the design of roadbed widening in highway reconstruction and expansion projects.展开更多
There are many problems in Social Internet of Things(IoTs),such as complex topology information,different degree of association between nodes and overlapping communities.The idea of set pair information grain computin...There are many problems in Social Internet of Things(IoTs),such as complex topology information,different degree of association between nodes and overlapping communities.The idea of set pair information grain computing and clustering is introduced to solve the above problems so as to accurately describe the similarity between nodes and fully explore the multi-community structure.A Set Pair Three-Way Overlapping Community Discovery Algorithm for Weighted Social Internet of Things(WSIoT-SPTOCD)is proposed.In the local network structure,which fully considers the topological information between nodes,the set pair connection degree is used to analyze the identity,difference and reverse of neighbor nodes.The similarity degree of different neighbor nodes is defined from network edge weight and node degree,and the similarity measurement method of set pair between nodes based on the local information structure is proposed.According to the number of nodes'neighbors and the connection degree of adjacent edges,the clustering intensity of nodes is defined,and an improved algorithm for initial value selection of k-means is proposed.The nodes are allocated according to the set pair similarity between nodes and different communities.Three-way community structures composed of a positive domain,boundary domain and negative domain are generated iteratively.Next,the overlapping node set is generated according to the calculation results of community node membership.Finally,experiments are carried out on artificial networks and real networks.The results show that WSIoT-SPTOCD performs well in terms of standardized mutual information,overlapping community modularity and F1.展开更多
Stress concentration occurs in the foundations of railway tracks where discontinuous components are located.The exacerbated stress under the expansion joints in slab tracks may trigger foundation failures such as mud ...Stress concentration occurs in the foundations of railway tracks where discontinuous components are located.The exacerbated stress under the expansion joints in slab tracks may trigger foundation failures such as mud pumping.Although the higher stress due to the discontinuities of track structures has been discussed in past studies,few focused on the stress response of roadbeds in slab tracks and quantitatively characterized the stress pattern.In this paper,we performed a dynamic finite element analysis of a track-formation system,incorporating expansion joints as primary longitudinal discontinuities.The configurations of CRTS Ⅲ slab tracks and the contact conditions between concrete layers were considered.Numerical results show that longitudinal influencing length of induced stress on roadbed under wheel load relates to the contact conditions between concrete layers,increasing nonlinearly at a larger coefficient of friction.Given a measured coefficient of friction of 0.7,the calculated longitudinal influencing length(9.0 m) matches with field data.The longitudinal influencing length is not affected with the increasing velocity.As stress concentration arises with expansion joints,the worstcase scenario emerges when double-axle loads are exerted immediately above the expansion joints between concrete bases.A stress concentration factor Cvon the roadbed is proposed;it increases with the increasing velocity,changing from 1.33 to 1.52 at velocities between 5 and 400 km/h.The stress distribution on roadbeds transforms from a trapezoid pattern at continuous sections to a triangle pattern at points with longitudinal discontinuities.An explicit expression is finally proposed for the stress pattern on roadbed under expansion joints.Although structural discontinuities induce stress raiser,the extent of concentration is mitigated with increasing depth at different velocity levels.展开更多
With the continuous development of China,the requirements for road construction are also increasing.Among them,strengthening the performance of roadbed test can effectively improve road construction.Besides,it is also...With the continuous development of China,the requirements for road construction are also increasing.Among them,strengthening the performance of roadbed test can effectively improve road construction.Besides,it is also crucial to perform suitable tests in a timely manner.Therefore,highway inspection technology should be improved for the continuous development of highway construction,which will be explained in this paper,in hopes of improving the construction of highway in China.展开更多
A two-stage automatic key frame selection method is proposed to enhance stitching speed and quality for UAV aerial videos. In the first stage, to reduce redundancy, the overlapping rate of the UAV aerial video sequenc...A two-stage automatic key frame selection method is proposed to enhance stitching speed and quality for UAV aerial videos. In the first stage, to reduce redundancy, the overlapping rate of the UAV aerial video sequence within the sampling period is calculated. Lagrange interpolation is used to fit the overlapping rate curve of the sequence. An empirical threshold for the overlapping rate is then applied to filter candidate key frames from the sequence. In the second stage, the principle of minimizing remapping spots is used to dynamically adjust and determine the final key frame close to the candidate key frames. Comparative experiments show that the proposed method significantly improves stitching speed and accuracy by more than 40%.展开更多
The effect of overlapping treatment on microstructure of laser clad WC/Ni60A composite coating was studied with XRD, SEM, TEM and SAED etc. The results show that during the overlapping treatment the existence of the r...The effect of overlapping treatment on microstructure of laser clad WC/Ni60A composite coating was studied with XRD, SEM, TEM and SAED etc. The results show that during the overlapping treatment the existence of the residual heat and edge angle effect on the substrate has changed the composition and microstructure of the coating by raising the fusion temperature and increasing the dilution degree of the coating.展开更多
This work is concerned with the analysis of blood flow through inclined catheterized arteries having a balloon(angioplasty) with time-variant overlapping stenosis. The nature of blood in small arteries is analyzed mat...This work is concerned with the analysis of blood flow through inclined catheterized arteries having a balloon(angioplasty) with time-variant overlapping stenosis. The nature of blood in small arteries is analyzed mathematically by considering it as a Carreau nanofluid. The highly nonlinear momentum equations of nanofluid model are simplified by considering the mild stenosis case. The formulated problem is solved by a homotopy perturbation expansion in terms of a variant of the Weissenberg number to obtain explicit forms for the axial velocity, the stream function, the pressure gradient, the resistance impedance and the wall shear stress distribution. These solutions depend on the Brownian motion number, thermophoresis number, local temperature Grashof number G_r and local nanoparticle Grash of number B_r. The results were also studied for various values of the physical parameters, such as the Weissenberg number W_i, the power law index n, the taper angle φ, the maximum height of stenosis δ~*, the angle of inclination α, the maximum height of balloon σ~*, the axial displacement of the balloon z_d~*,the flow rate F and the Froud number Fr. The obtained results show that the transmission of axial velocity curves through a Newtonian fluid(Wi=0, n=1, Gr=0, Br=0, Nt=0, Nb≠0) is substantially lower than that through a Carreau nanofluid near the wall of balloon while the inverse occurs in the region between the balloon and stenosis. The streamlines have a clearly distinguished shifting toward the stenotic region and this shifting appears near the wall of the balloon, while it has almost disappeared near the stenotic wall and the trapping bolus in the case of horizontal arteries and Newtonian fluid(Wi=0, n=1, Gr=0, Br=0, Nt=0, Nb≠0) does not appear but for the case of Carreau nanofluid bolus appears.展开更多
Aluminum alloy 5 A02 with low plasticity was used as target sheet, and stainless steel SUS304 with good plasticity was used as overlapping sheet to investigate the effect of interface friction on bulging formability a...Aluminum alloy 5 A02 with low plasticity was used as target sheet, and stainless steel SUS304 with good plasticity was used as overlapping sheet to investigate the effect of interface friction on bulging formability and microstructure of target sheet in overlapping sheets bulging process. Sheet sliding experiment was performed to measure interface friction coefficient of 5 A02/SUS304 in different lubricating conditions and normal pressure. Overlapping sheets bulging experiment of 5 A02/SUS304 was carried out to investigate the influence of interface friction on limit bulging height, wall thickness distribution, microstructure and fracture morphology of 5 A02 bulging specimens. The results showed that increase of the interface friction coefficient of 5 A02/SUS304 could effectively improve the limit bulging height and deformation uniformity of 5 A02. And the fracture style of 5 A02 transformed from toughness fracture of dimples-micropores gathered to fault slip separation fracture. Therefore, target sheet bulging formability is improved with the increase of interface friction coefficient.展开更多
Identification of nuclear pulse signal is of importance in radioactive measurements,especially in recognizing adjacent overlapping nuclear pulses.In this article,we propose an estimation method for parameters of typic...Identification of nuclear pulse signal is of importance in radioactive measurements,especially in recognizing adjacent overlapping nuclear pulses.In this article,we propose an estimation method for parameters of typical overlapping nuclear pulse signals.First,the nuclear pulses are regarded as individual genes and the norm is set as the fitness function.Second,the global optimal solution is found by searching the population of genetic algorithm,so as to estimate the parameters of nuclear pulse.With high precision,this method can identify parameters of overlapping nuclear pulses in the Sallen-Key Gaussian signal decomposition experiments.This pulse recognition method is of great significance to improve the precision of radioactive measurement and is suitable for serious overlap of nuclear pluses.展开更多
The influenza A viruses have three gene segments, M, NS, and PB1, which code for more than one protein. The overlapping genes from the same segment entail their interdependence, which could be reflected in the evoluti...The influenza A viruses have three gene segments, M, NS, and PB1, which code for more than one protein. The overlapping genes from the same segment entail their interdependence, which could be reflected in the evolutionary constraints, host distinction, and co-mutations of influenza. Most previous studies of overlapping genes focused on their unique evolutionary constraints, and very little was achieved to assess the potential impact of the overlap on other biological aspects of influenza. In this study, our aim was to explore the mutual dependence in host differentiation and co-mutations in M, NS, and PB1 of avian, human, 2009 H1N1, and swine viruses, with Random Forests, information entropy, and mutual information. The host markers and highly co-mutated individual sites and site pairs (P values < 0.035) in the three gene segments were identified with their relative significance between the overlapping genes calculated. Further, Random Forests predicted that among the three stop codons in the current PB1-F2 gene of 2009 H1N1, the significance of a mutation at these sites for host differentiation was, in order from most to least, that at 12, 58, and 88, i.e., the closer to the start of the gene the more important the mutation was. Finally, our sequence analysis surprisingly revealed that the full-length PB1-F2, if the three stop codons were all mutated, would function more as a swine protein than a human protein, although the PB1 of 2009 H1N1 was derived from human H3N2.展开更多
Community discovery of complex networks,esp.of social networks,has been a hotly debated topic in academic circles in recent years.Since actual networks usually contain some overlapping nodes that are difficult to assi...Community discovery of complex networks,esp.of social networks,has been a hotly debated topic in academic circles in recent years.Since actual networks usually contain some overlapping nodes that are difficult to assign to a certain community,overlapping community discovery is under great demand in practical applications.However,at present network community discovery is mainly done by non-overlapping community discovery methods,overlapping discovery methods are not common.In this context,an overlapping community discovery method is proposed hereby based on topological potential and specific algorithms are also provided.This method not only considers the spread of the uncertainty of community identity of the overlapping nodes in the network,but also realizes a quantified representation,i.e.,uncertainty measure,of the community identity of the overlapping nodes.The experiment results show that this method yields the results that are consistent with those by the classic methods and are more reasonable.展开更多
The failure data at the system level are often limited,resulting in high uncertainty to system reliability assessment. Integrating data drawn from various structural levels of the target system(e.g. the system, subsys...The failure data at the system level are often limited,resulting in high uncertainty to system reliability assessment. Integrating data drawn from various structural levels of the target system(e.g. the system, subsystems, assemblies and components), i.e. the multi-level data, through Bayesian analysis can improve the precision of system reliability assessment. However, if the multi-level data are overlapping, it is challenging for Bayesian integration to develop the likelihood function. Especially for multistate systems(MSS), the Bayesian integration with overlapping data is even more difficult. The major disadvantage of previous approaches is the intensive computation for the development of the likelihood function caused by the workload to opt the appropriate combinations of the vectors of component states consistent with the overlapping data. An improved fully Bayesian integration approach from a geometric perspective is proposed for the reliability assessment of MSS with overlapping data. In this method, a specific combination of component states is regarded as a state vector, which leads to a specific system state of the MSS, and all state vectors generate a system state space. The overlapping data are regarded as the constraints which create hyperplanes in the system state space. And a point in a hyperplane corresponds to a particular combination of the state vectors. In the light of the features of the constraints, the proposed approach introduces space partition and hyperplane segmentation, which reduces the selection workload significantly and simplifies the likelihood function for overlapping data. Two examples demonstrate the feasibility and efficiency of the proposed approach.展开更多
AIM: The incorporation of hepatitis B virus (HBV) preS1 region into epitope-based vaccines against HBV has been accepted widely, but the incorporate site and size of preS1 sequence is controversial. Therefore our purp...AIM: The incorporation of hepatitis B virus (HBV) preS1 region into epitope-based vaccines against HBV has been accepted widely, but the incorporate site and size of preS1 sequence is controversial. Therefore our purpose was to further investigate its immunogenic domains for the epitopebased hepatitis B vaccine design.METHODS: Eight GST fusion proteins containing overlapping preS1 fragments in preS1 (21-119) region were expressed in E.coli. Using these purified fusion proteins, the immunogenic domains in preS1 region were identified in detail in mice and humans by Western blot analysis and ELISA.RESULTS: The results in mice showed that the immunogenic domains mainly existed in preS1 (21-59) and preS1 (95-109). Similarly, these fragments had strong immunogenicity in humans; whereas the other parts except for preS1 (60-70) also had some immunogenicity.More importantly, a major immunogenic domain, preS1 (34-59), which has much stronger immunogenicity, was identified. Additionally, the antibodies against some preS1 fragments, especially preS1 (34-59), were speculated to be virus-neutralizing.CONCLUSION: Eight GST fusion proteins containing overlapping preS1 fragments were prepared successfully. They were used for the study on the immunogenic domains in preS1 (21-119) region. The preS1 (34-59) fragments were the major immunogenic domains in the preS1 region, and the antibodies against these fragments were speculated to be virus-neutralizing. Therefore, the incorporation of preS1 (34-59) fragments into epitopebased HBV vaccines may be efficient for enhancement of immune response. Additionally, the results also imply that there are more complex immune responses to preS1 region and more abundant immunogenic domains in humans.展开更多
Purpose: This paper intends to explore methodologies and indicators for the analysis of overlapping structures and evolution properties in a co-citation network, and provide reference for overlapping structure analysi...Purpose: This paper intends to explore methodologies and indicators for the analysis of overlapping structures and evolution properties in a co-citation network, and provide reference for overlapping structure analysis of other scientific networks.Design/methodology/approach: The Q-value variance is defined to achieve overlapping structures of different levels in the scientific networks. At the same time, analyses for time correlation variance and subject correlation variance are used to present the formation of overlapping structures in scientific networks. As a test, a co-citation network of highly cited papers on Molecular Biology & Genetics from Essential Science Indicator(ESI) is taken as an example for an empirical analysis.Findings: Our research showed that the Q-value variance is effective for achieving the desired overlapping structures. Meanwhile, the time correlation variance and subject correlation variance are equally useful for uncovering the evolution progress of scientific research, and the properties of overlapping structures in the research of co-citation network as well.Research limitations: In this paper, the theoretical analysis and verification of time and subject correlation variances are still at its initial stage. Further studies in this regard need to take actual evolution of research areas into consideration.Practical implications: Evolution properties of overlapping structures pave the way for overlapping and evolution analysis of disciplines or areas, this study is of practical value for the planning of scientific and technical innovation.Originality/value: This paper proposes an analytical method of time correlation variance and subject correlation variance based on the evolution properties of overlapping structures, which would provide the foundation for the evolution analysis of disciplines and interdisciplinary research.展开更多
The deformation and strength characteristics of roadbed slope under seismic loading in permafrost regions are simulated numerically. The seismic response of roadbed at different positions and inclinations of a slope s...The deformation and strength characteristics of roadbed slope under seismic loading in permafrost regions are simulated numerically. The seismic response of roadbed at different positions and inclinations of a slope section was analyzed.Results show that, roadbed slope damage is mainly led by lateral displacement, and the deformation gradually decreases with increasing depth; roadbed and foundation displacement and plastic strain increases with the magnitude of slope angle,hence the roadbed safety factor will be reduced.展开更多
According to the main characters of overlapping underground chambers, the roof (floor) of two adjacent underground chambers is simplified to the mechanical model that is the beam with build-in ends. And vibration load...According to the main characters of overlapping underground chambers, the roof (floor) of two adjacent underground chambers is simplified to the mechanical model that is the beam with build-in ends. And vibration load due to blasting is simplified to harmonic wave. The catastrophic model of double cusp for underground chambers destabilization induced by blasting vibration has been established under the circumstances of considering deadweight of the beam, and the condition of destabilization has been worked out. The critical safety thickness of the roof (floor) of underground chambers has been confirmed according to the destabilization condition. The influence of amplitude and frequency of blasting vibration load on the critical safety thickness has been analyzed, and the quantitative relation between velocity, frequency of blasting vibration and critical safety thickness has been determined. Research results show that the destabilization of underground chambers is not only dependent on the amplitude and frequency of blasting vibration load, but also related to deadweight load and intrinsic attribute. It is accordant to testing results and some related latest research results of blasting seismic effect. With increasing amplitude, the critical safety thickness of underground chambers decreases gradually. And the possibility of underground chambers destabilization increases. When the frequency of blasting vibration is equal to or very close to the frequency of beam, resonance effect will take place in the system. Then the critical safety thickness will turn to zero, underground chambers will be damaged severely, and its loading capacity will lose on the whole.展开更多
基金supported in part by the Central Government Guides Local Science and TechnologyDevelopment Funds(Grant No.YDZJSX2021A038)in part by theNational Natural Science Foundation of China under(Grant No.61806138)in part by the China University Industry-University-Research Collaborative Innovation Fund(Future Network Innovation Research and Application Project)(Grant 2021FNA04014).
文摘The large-scale multi-objective optimization algorithm(LSMOA),based on the grouping of decision variables,is an advanced method for handling high-dimensional decision variables.However,in practical problems,the interaction among decision variables is intricate,leading to large group sizes and suboptimal optimization effects;hence a large-scale multi-objective optimization algorithm based on weighted overlapping grouping of decision variables(MOEAWOD)is proposed in this paper.Initially,the decision variables are perturbed and categorized into convergence and diversity variables;subsequently,the convergence variables are subdivided into groups based on the interactions among different decision variables.If the size of a group surpasses the set threshold,that group undergoes a process of weighting and overlapping grouping.Specifically,the interaction strength is evaluated based on the interaction frequency and number of objectives among various decision variables.The decision variable with the highest interaction in the group is identified and disregarded,and the remaining variables are then reclassified into subgroups.Finally,the decision variable with the strongest interaction is added to each subgroup.MOEAWOD minimizes the interactivity between different groups and maximizes the interactivity of decision variables within groups,which contributed to the optimized direction of convergence and diversity exploration with different groups.MOEAWOD was subjected to testing on 18 benchmark large-scale optimization problems,and the experimental results demonstrate the effectiveness of our methods.Compared with the other algorithms,our method is still at an advantage.
基金Supported by The Guangxi TCM Suitable Technology Development and Promotion Project,No.GZSY20-20.
文摘BACKGROUND Infections by non-tuberculous mycobacteria(NTM)have become more common in recent years.Mycobacterium canariasense(M.canariasense)was first reported as an opportunistic pathogen in 2004,but there have been very few case reports since then.Nocardia is a genus of aerobic and Gram-positive bacilli,and these species are also opportunistic pathogens and in the Mycobacteriales order.Conventional methods for diagnosis of NTM are inefficient.Metagenomic next-generation sequencing(mNGS)can rapidly detect many pathogenic microorganisms,even rare species.Most NTM and Nocardia infections occur in immunocompromised patients with atypical clinical symptoms.There are no previous reports of infection by M.canariasense and Nocardia farcinica(N.farcinica),especially in immunocompetent patients.This case report describes an immunocompetent 52-year-old woman who had overlapping infections of M.canariasense,N.farcinica,and Candida parapsilosis(C.parapsilosis)based on mNGS.CASE SUMMARY A 52-year-old woman presented with a productive cough and chest pain for 2 wk,and recurrent episodes of moderate-grade fever for 1 wk.She received antibiotics for 1 wk at a local hospital,and experienced defervescence,but the productive cough and chest pain persisted.We collected samples of a lung lesion and alveolar lavage fluid for mNGS.The lung tissue was positive for M.canariasense,N.farcinica,and C.parapsilosis,and the alveolar lavage fluid was positive for M.canariasense.The diagnosis was pneumonia,and application of appropriate antibiotic therapy cured the patient.CONCLUSION Etiological diagnosis is critical for patients with infectious diseases.mNGS can identify rare and novel pathogens,and does not require a priori knowledge.
文摘This article discusses the roadbed splicing for hub interchanges.The article starts with a description of the characteristics of junction roadbed splicing.The application of splicing technology is explained using a subgrade splicing scheme of a project.Roadbed splicing involves stepwise excavation and preparative measures like surface cleaning and backfilling.This article serves to provide a valuable reference for road and bridge construction and improve the quality of China’s road and bridge projects,so as to achieve sustainable development of the road and bridge engineering industry.
文摘This article analyzes the differential settlement of new and old roadbeds after widening and its characteristics based on a highway reconstruction and expansion project case study.The research proposes a subgrade settlement control standard that states that the maximum differential settlement value should be less than 5 cm when the embankment fill height exceeds 20 m.Similarly,the maximum differential settlement value should be less than 10 cm when the embankment fill height does not exceed 20 m.The findings of the study can provide a useful reference for the design of roadbed widening in highway reconstruction and expansion projects.
文摘There are many problems in Social Internet of Things(IoTs),such as complex topology information,different degree of association between nodes and overlapping communities.The idea of set pair information grain computing and clustering is introduced to solve the above problems so as to accurately describe the similarity between nodes and fully explore the multi-community structure.A Set Pair Three-Way Overlapping Community Discovery Algorithm for Weighted Social Internet of Things(WSIoT-SPTOCD)is proposed.In the local network structure,which fully considers the topological information between nodes,the set pair connection degree is used to analyze the identity,difference and reverse of neighbor nodes.The similarity degree of different neighbor nodes is defined from network edge weight and node degree,and the similarity measurement method of set pair between nodes based on the local information structure is proposed.According to the number of nodes'neighbors and the connection degree of adjacent edges,the clustering intensity of nodes is defined,and an improved algorithm for initial value selection of k-means is proposed.The nodes are allocated according to the set pair similarity between nodes and different communities.Three-way community structures composed of a positive domain,boundary domain and negative domain are generated iteratively.Next,the overlapping node set is generated according to the calculation results of community node membership.Finally,experiments are carried out on artificial networks and real networks.The results show that WSIoT-SPTOCD performs well in terms of standardized mutual information,overlapping community modularity and F1.
基金This work was supported by the National Natural Science Foundation of China(Nos.41901073 and 52078435)the Sichuan Science and Technology Program(No.2021YJ0001)。
文摘Stress concentration occurs in the foundations of railway tracks where discontinuous components are located.The exacerbated stress under the expansion joints in slab tracks may trigger foundation failures such as mud pumping.Although the higher stress due to the discontinuities of track structures has been discussed in past studies,few focused on the stress response of roadbeds in slab tracks and quantitatively characterized the stress pattern.In this paper,we performed a dynamic finite element analysis of a track-formation system,incorporating expansion joints as primary longitudinal discontinuities.The configurations of CRTS Ⅲ slab tracks and the contact conditions between concrete layers were considered.Numerical results show that longitudinal influencing length of induced stress on roadbed under wheel load relates to the contact conditions between concrete layers,increasing nonlinearly at a larger coefficient of friction.Given a measured coefficient of friction of 0.7,the calculated longitudinal influencing length(9.0 m) matches with field data.The longitudinal influencing length is not affected with the increasing velocity.As stress concentration arises with expansion joints,the worstcase scenario emerges when double-axle loads are exerted immediately above the expansion joints between concrete bases.A stress concentration factor Cvon the roadbed is proposed;it increases with the increasing velocity,changing from 1.33 to 1.52 at velocities between 5 and 400 km/h.The stress distribution on roadbeds transforms from a trapezoid pattern at continuous sections to a triangle pattern at points with longitudinal discontinuities.An explicit expression is finally proposed for the stress pattern on roadbed under expansion joints.Although structural discontinuities induce stress raiser,the extent of concentration is mitigated with increasing depth at different velocity levels.
文摘With the continuous development of China,the requirements for road construction are also increasing.Among them,strengthening the performance of roadbed test can effectively improve road construction.Besides,it is also crucial to perform suitable tests in a timely manner.Therefore,highway inspection technology should be improved for the continuous development of highway construction,which will be explained in this paper,in hopes of improving the construction of highway in China.
文摘A two-stage automatic key frame selection method is proposed to enhance stitching speed and quality for UAV aerial videos. In the first stage, to reduce redundancy, the overlapping rate of the UAV aerial video sequence within the sampling period is calculated. Lagrange interpolation is used to fit the overlapping rate curve of the sequence. An empirical threshold for the overlapping rate is then applied to filter candidate key frames from the sequence. In the second stage, the principle of minimizing remapping spots is used to dynamically adjust and determine the final key frame close to the candidate key frames. Comparative experiments show that the proposed method significantly improves stitching speed and accuracy by more than 40%.
文摘The effect of overlapping treatment on microstructure of laser clad WC/Ni60A composite coating was studied with XRD, SEM, TEM and SAED etc. The results show that during the overlapping treatment the existence of the residual heat and edge angle effect on the substrate has changed the composition and microstructure of the coating by raising the fusion temperature and increasing the dilution degree of the coating.
文摘This work is concerned with the analysis of blood flow through inclined catheterized arteries having a balloon(angioplasty) with time-variant overlapping stenosis. The nature of blood in small arteries is analyzed mathematically by considering it as a Carreau nanofluid. The highly nonlinear momentum equations of nanofluid model are simplified by considering the mild stenosis case. The formulated problem is solved by a homotopy perturbation expansion in terms of a variant of the Weissenberg number to obtain explicit forms for the axial velocity, the stream function, the pressure gradient, the resistance impedance and the wall shear stress distribution. These solutions depend on the Brownian motion number, thermophoresis number, local temperature Grashof number G_r and local nanoparticle Grash of number B_r. The results were also studied for various values of the physical parameters, such as the Weissenberg number W_i, the power law index n, the taper angle φ, the maximum height of stenosis δ~*, the angle of inclination α, the maximum height of balloon σ~*, the axial displacement of the balloon z_d~*,the flow rate F and the Froud number Fr. The obtained results show that the transmission of axial velocity curves through a Newtonian fluid(Wi=0, n=1, Gr=0, Br=0, Nt=0, Nb≠0) is substantially lower than that through a Carreau nanofluid near the wall of balloon while the inverse occurs in the region between the balloon and stenosis. The streamlines have a clearly distinguished shifting toward the stenotic region and this shifting appears near the wall of the balloon, while it has almost disappeared near the stenotic wall and the trapping bolus in the case of horizontal arteries and Newtonian fluid(Wi=0, n=1, Gr=0, Br=0, Nt=0, Nb≠0) does not appear but for the case of Carreau nanofluid bolus appears.
基金Funded by the National Natural Science Foundation of China(No.51575364)the Program for Liaoning Innovation Talents in University(No.LR2017069)the Shenyang Science and Technology Innovation Support Program for Young Talented People(No.RC180189)
文摘Aluminum alloy 5 A02 with low plasticity was used as target sheet, and stainless steel SUS304 with good plasticity was used as overlapping sheet to investigate the effect of interface friction on bulging formability and microstructure of target sheet in overlapping sheets bulging process. Sheet sliding experiment was performed to measure interface friction coefficient of 5 A02/SUS304 in different lubricating conditions and normal pressure. Overlapping sheets bulging experiment of 5 A02/SUS304 was carried out to investigate the influence of interface friction on limit bulging height, wall thickness distribution, microstructure and fracture morphology of 5 A02 bulging specimens. The results showed that increase of the interface friction coefficient of 5 A02/SUS304 could effectively improve the limit bulging height and deformation uniformity of 5 A02. And the fracture style of 5 A02 transformed from toughness fracture of dimples-micropores gathered to fault slip separation fracture. Therefore, target sheet bulging formability is improved with the increase of interface friction coefficient.
基金supported by the National Natural Science Foundation of China(No.41204133)Sichuan Province Science and Technology Support Program(No.2014GZ0020)+1 种基金the Open Science Fund from Key Laboratory of Radioactive Geology and Exploration Technology Fundamental Science for National Defense,East China Institute of Technology(No.RGET1401)Scientific Research Fund of Sichuan Provincial Education Department(No.13ZA0066)
文摘Identification of nuclear pulse signal is of importance in radioactive measurements,especially in recognizing adjacent overlapping nuclear pulses.In this article,we propose an estimation method for parameters of typical overlapping nuclear pulse signals.First,the nuclear pulses are regarded as individual genes and the norm is set as the fitness function.Second,the global optimal solution is found by searching the population of genetic algorithm,so as to estimate the parameters of nuclear pulse.With high precision,this method can identify parameters of overlapping nuclear pulses in the Sallen-Key Gaussian signal decomposition experiments.This pulse recognition method is of great significance to improve the precision of radioactive measurement and is suitable for serious overlap of nuclear pluses.
文摘The influenza A viruses have three gene segments, M, NS, and PB1, which code for more than one protein. The overlapping genes from the same segment entail their interdependence, which could be reflected in the evolutionary constraints, host distinction, and co-mutations of influenza. Most previous studies of overlapping genes focused on their unique evolutionary constraints, and very little was achieved to assess the potential impact of the overlap on other biological aspects of influenza. In this study, our aim was to explore the mutual dependence in host differentiation and co-mutations in M, NS, and PB1 of avian, human, 2009 H1N1, and swine viruses, with Random Forests, information entropy, and mutual information. The host markers and highly co-mutated individual sites and site pairs (P values < 0.035) in the three gene segments were identified with their relative significance between the overlapping genes calculated. Further, Random Forests predicted that among the three stop codons in the current PB1-F2 gene of 2009 H1N1, the significance of a mutation at these sites for host differentiation was, in order from most to least, that at 12, 58, and 88, i.e., the closer to the start of the gene the more important the mutation was. Finally, our sequence analysis surprisingly revealed that the full-length PB1-F2, if the three stop codons were all mutated, would function more as a swine protein than a human protein, although the PB1 of 2009 H1N1 was derived from human H3N2.
基金Sponsored by the National Natural Science Foundation of China(Grant No.61073041,60873037,61100008 and 61073043)the Natural Science Foundation of Heilongjiang Province(Grant No.F200901 and F201023)+1 种基金the Harbin Special Funds for Technological Innovation Research(Grant No. 2010RFXXG002 and 2011RFXXG015)the Fundamental Research Funds for the Central Universities of China(Grant No.HEUCF100602)
文摘Community discovery of complex networks,esp.of social networks,has been a hotly debated topic in academic circles in recent years.Since actual networks usually contain some overlapping nodes that are difficult to assign to a certain community,overlapping community discovery is under great demand in practical applications.However,at present network community discovery is mainly done by non-overlapping community discovery methods,overlapping discovery methods are not common.In this context,an overlapping community discovery method is proposed hereby based on topological potential and specific algorithms are also provided.This method not only considers the spread of the uncertainty of community identity of the overlapping nodes in the network,but also realizes a quantified representation,i.e.,uncertainty measure,of the community identity of the overlapping nodes.The experiment results show that this method yields the results that are consistent with those by the classic methods and are more reasonable.
基金supported by the National Natural Science Foundation of China(61304218)the Beijing Higher Education Young Elite Teacher Project(YETP1123)
文摘The failure data at the system level are often limited,resulting in high uncertainty to system reliability assessment. Integrating data drawn from various structural levels of the target system(e.g. the system, subsystems, assemblies and components), i.e. the multi-level data, through Bayesian analysis can improve the precision of system reliability assessment. However, if the multi-level data are overlapping, it is challenging for Bayesian integration to develop the likelihood function. Especially for multistate systems(MSS), the Bayesian integration with overlapping data is even more difficult. The major disadvantage of previous approaches is the intensive computation for the development of the likelihood function caused by the workload to opt the appropriate combinations of the vectors of component states consistent with the overlapping data. An improved fully Bayesian integration approach from a geometric perspective is proposed for the reliability assessment of MSS with overlapping data. In this method, a specific combination of component states is regarded as a state vector, which leads to a specific system state of the MSS, and all state vectors generate a system state space. The overlapping data are regarded as the constraints which create hyperplanes in the system state space. And a point in a hyperplane corresponds to a particular combination of the state vectors. In the light of the features of the constraints, the proposed approach introduces space partition and hyperplane segmentation, which reduces the selection workload significantly and simplifies the likelihood function for overlapping data. Two examples demonstrate the feasibility and efficiency of the proposed approach.
文摘AIM: The incorporation of hepatitis B virus (HBV) preS1 region into epitope-based vaccines against HBV has been accepted widely, but the incorporate site and size of preS1 sequence is controversial. Therefore our purpose was to further investigate its immunogenic domains for the epitopebased hepatitis B vaccine design.METHODS: Eight GST fusion proteins containing overlapping preS1 fragments in preS1 (21-119) region were expressed in E.coli. Using these purified fusion proteins, the immunogenic domains in preS1 region were identified in detail in mice and humans by Western blot analysis and ELISA.RESULTS: The results in mice showed that the immunogenic domains mainly existed in preS1 (21-59) and preS1 (95-109). Similarly, these fragments had strong immunogenicity in humans; whereas the other parts except for preS1 (60-70) also had some immunogenicity.More importantly, a major immunogenic domain, preS1 (34-59), which has much stronger immunogenicity, was identified. Additionally, the antibodies against some preS1 fragments, especially preS1 (34-59), were speculated to be virus-neutralizing.CONCLUSION: Eight GST fusion proteins containing overlapping preS1 fragments were prepared successfully. They were used for the study on the immunogenic domains in preS1 (21-119) region. The preS1 (34-59) fragments were the major immunogenic domains in the preS1 region, and the antibodies against these fragments were speculated to be virus-neutralizing. Therefore, the incorporation of preS1 (34-59) fragments into epitopebased HBV vaccines may be efficient for enhancement of immune response. Additionally, the results also imply that there are more complex immune responses to preS1 region and more abundant immunogenic domains in humans.
基金supported by the National Science Library of Chinese Academy of Sciences
文摘Purpose: This paper intends to explore methodologies and indicators for the analysis of overlapping structures and evolution properties in a co-citation network, and provide reference for overlapping structure analysis of other scientific networks.Design/methodology/approach: The Q-value variance is defined to achieve overlapping structures of different levels in the scientific networks. At the same time, analyses for time correlation variance and subject correlation variance are used to present the formation of overlapping structures in scientific networks. As a test, a co-citation network of highly cited papers on Molecular Biology & Genetics from Essential Science Indicator(ESI) is taken as an example for an empirical analysis.Findings: Our research showed that the Q-value variance is effective for achieving the desired overlapping structures. Meanwhile, the time correlation variance and subject correlation variance are equally useful for uncovering the evolution progress of scientific research, and the properties of overlapping structures in the research of co-citation network as well.Research limitations: In this paper, the theoretical analysis and verification of time and subject correlation variances are still at its initial stage. Further studies in this regard need to take actual evolution of research areas into consideration.Practical implications: Evolution properties of overlapping structures pave the way for overlapping and evolution analysis of disciplines or areas, this study is of practical value for the planning of scientific and technical innovation.Originality/value: This paper proposes an analytical method of time correlation variance and subject correlation variance based on the evolution properties of overlapping structures, which would provide the foundation for the evolution analysis of disciplines and interdisciplinary research.
基金National 973 Project of China (No.2012CB026104)National Natural Science Foundation of China (No.41171064)
文摘The deformation and strength characteristics of roadbed slope under seismic loading in permafrost regions are simulated numerically. The seismic response of roadbed at different positions and inclinations of a slope section was analyzed.Results show that, roadbed slope damage is mainly led by lateral displacement, and the deformation gradually decreases with increasing depth; roadbed and foundation displacement and plastic strain increases with the magnitude of slope angle,hence the roadbed safety factor will be reduced.
基金Project(50490272) supported by the National Natural Science Foundation of China Project(040109) supported by the Doctor Degree Paper Innovation Engineering of Central South University
文摘According to the main characters of overlapping underground chambers, the roof (floor) of two adjacent underground chambers is simplified to the mechanical model that is the beam with build-in ends. And vibration load due to blasting is simplified to harmonic wave. The catastrophic model of double cusp for underground chambers destabilization induced by blasting vibration has been established under the circumstances of considering deadweight of the beam, and the condition of destabilization has been worked out. The critical safety thickness of the roof (floor) of underground chambers has been confirmed according to the destabilization condition. The influence of amplitude and frequency of blasting vibration load on the critical safety thickness has been analyzed, and the quantitative relation between velocity, frequency of blasting vibration and critical safety thickness has been determined. Research results show that the destabilization of underground chambers is not only dependent on the amplitude and frequency of blasting vibration load, but also related to deadweight load and intrinsic attribute. It is accordant to testing results and some related latest research results of blasting seismic effect. With increasing amplitude, the critical safety thickness of underground chambers decreases gradually. And the possibility of underground chambers destabilization increases. When the frequency of blasting vibration is equal to or very close to the frequency of beam, resonance effect will take place in the system. Then the critical safety thickness will turn to zero, underground chambers will be damaged severely, and its loading capacity will lose on the whole.
