本研究采用5 Gy X 射线全身照射雄性大鼠,观察人参三醇组甙对下丘脑-垂体-睾丸系统功能的影响。动物于照前24 h 及照后每天经腹腔给予三醇组甙5 mg,共14次。实验结果表明,单纯照射组与正常对照组比较,睾丸组织受到明显损伤,血清睾丸酮...本研究采用5 Gy X 射线全身照射雄性大鼠,观察人参三醇组甙对下丘脑-垂体-睾丸系统功能的影响。动物于照前24 h 及照后每天经腹腔给予三醇组甙5 mg,共14次。实验结果表明,单纯照射组与正常对照组比较,睾丸组织受到明显损伤,血清睾丸酮水平和睾丸环磷酸腺苷(cAMP)及下丘脑亮氨酸脑啡肽(L-Enk)含量明显降低,血清滤泡刺激素(FSH)水平明显增加;但在照射加人参组中,上述指标都接近正常对照组水平。提示人参三醇组甙可减轻受照大鼠生殖内分泌轴的损伤,具有保护下丘脑-垂体-性腺系统功能的作用,并促进其辐射损伤的恢复过程。展开更多
Panaxatriol ginsenoside (PTGS) is the major element of ginsenoside. It was shown that ginsenoside could regulate the functions of several immune cells, possibly mediated by enhanced secretion of interleukine-2 (IL-2) ...Panaxatriol ginsenoside (PTGS) is the major element of ginsenoside. It was shown that ginsenoside could regulate the functions of several immune cells, possibly mediated by enhanced secretion of interleukine-2 (IL-2) and interferon (IFN) . Recently, it was shown that the promotion of cytokines (IL-1, 2, 3, 4, 5, 6, IFN)with PTGS was related展开更多
It was shown that the enhancement of interleukin-2 (IL-2) production by lymphocytes stimulated with phytohemagglutinin (PHA) and promoted by panaxatriol ginsenoside (PTGS) was related to augmentation of protein synthe...It was shown that the enhancement of interleukin-2 (IL-2) production by lymphocytes stimulated with phytohemagglutinin (PHA) and promoted by panaxatriol ginsenoside (PTGS) was related to augmentation of protein synthesis, but not to that of RNA synthesis, by using radioisotope-labeling method. The results of further experiments展开更多
文摘本研究采用5 Gy X 射线全身照射雄性大鼠,观察人参三醇组甙对下丘脑-垂体-睾丸系统功能的影响。动物于照前24 h 及照后每天经腹腔给予三醇组甙5 mg,共14次。实验结果表明,单纯照射组与正常对照组比较,睾丸组织受到明显损伤,血清睾丸酮水平和睾丸环磷酸腺苷(cAMP)及下丘脑亮氨酸脑啡肽(L-Enk)含量明显降低,血清滤泡刺激素(FSH)水平明显增加;但在照射加人参组中,上述指标都接近正常对照组水平。提示人参三醇组甙可减轻受照大鼠生殖内分泌轴的损伤,具有保护下丘脑-垂体-性腺系统功能的作用,并促进其辐射损伤的恢复过程。
文摘Panaxatriol ginsenoside (PTGS) is the major element of ginsenoside. It was shown that ginsenoside could regulate the functions of several immune cells, possibly mediated by enhanced secretion of interleukine-2 (IL-2) and interferon (IFN) . Recently, it was shown that the promotion of cytokines (IL-1, 2, 3, 4, 5, 6, IFN)with PTGS was related
文摘It was shown that the enhancement of interleukin-2 (IL-2) production by lymphocytes stimulated with phytohemagglutinin (PHA) and promoted by panaxatriol ginsenoside (PTGS) was related to augmentation of protein synthesis, but not to that of RNA synthesis, by using radioisotope-labeling method. The results of further experiments
