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Management of Penetrating Cranioencephalic Trauma Caused by Sharp Metal Objects—Therapeutic and Evolutionary Aspects: 12 Cases at the Renaissance University Hospital in N’Djamena
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作者 Goumantar Félicien Toudjingar Li-Iyane Olivier Ouambi +3 位作者 Yannick Canton Kessely Donal Djasdé Mahouli Fata Vounki Momar Codé Ba 《Open Journal of Modern Neurosurgery》 2024年第2期170-178,共9页
Introduction: Cranioencephalic trauma caused by bladed weapons is rare, and that caused by sharp objects is exceptional. The aim of our study was to describe the clinical, therapeutic and evolutionary aspects. Materia... Introduction: Cranioencephalic trauma caused by bladed weapons is rare, and that caused by sharp objects is exceptional. The aim of our study was to describe the clinical, therapeutic and evolutionary aspects. Materials and method: This was a descriptive and analytical study over a 48-month period at CHU la Renaissance from January 1, 2018 to December 31, 2021, concerning patients admitted for penetrating cranioencephalic trauma by pointed object. Results: Twelve cases, all male, of penetrating cranioencephalic sharp-force trauma were identified. The mean age was 34 ± 7 years, with extremes of 11 and 60 years. Farmers and herders accounted for 31% and 25% of cases respectively. The average admission time was 47 hours. Brawls were the circumstances of occurrence in 81.2% of cases. Knives (33%), arrows (25%) and iron bars (16.6%) were the objects used. Altered consciousness was present in 43.8% of cases, and focal deficit in 50%. Scannographic lesions were fracture and/or embarrhment (12 cases), intra-parenchymal haematomas (6 cases) and presence of object in place (4 cases). Surgery was performed in 11 patients. Postoperative outcome was favorable in 9 patients. After 12 months, 2 patients were declared unfit. Conclusion: Penetrating head injuries caused by sharp objects are common in Chad. Urgent surgery can prevent disabling after-effects. 展开更多
关键词 penetrating trauma SKULL Encephalon Sharp Object Surgery Patient Outcome
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Delayed Pseudoaneurysms of Vertebral Artery Post Penetrating Trauma: A Case Report
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作者 Ahmad Rezaee Azandariani Leili Ebrahimi Farsangi Mohammad Mahdi Talimkhani 《Case Reports in Clinical Medicine》 2024年第4期95-100,共6页
Objective: Vascular injuries usually present immediately after the penetration, but the delayed onset of vascular symptoms caused by vessel dissection or aneurysm after a traumatic event is extremely rare. Vertebral a... Objective: Vascular injuries usually present immediately after the penetration, but the delayed onset of vascular symptoms caused by vessel dissection or aneurysm after a traumatic event is extremely rare. Vertebral artery injury is a low-frequency but high-mortality injury. We aim to report evidence of delayed onset of vascular symptoms following penetrating trauma in the neck. Materials and Methods: A case report. Results: A 19-year-old boy was referred to our hospital and complained of a mass in the right part of his neck (right mandibular angle). He gave a history of penetrating trauma to his neck 2 months ago. The mass was expanding during these 2 months and doesn’t respond to antibiotic therapy. In the examination, 3 × 3 cm, firm, nonmobile, and without tenderness and pain mass was palpated in the second level of his neck. Doctors ordered a Doppler sonography in the hospital where a yin-yang pattern was reported. A 36 × 43 × 40 mm heterogeneous, solid, and hypodense area close to C1-C2-C3 with vascular flow was discovered in the right submandibular area after computed tomography (CT)-angiography. The patient was referred to an interventional neurologist for angiography and due to the lack of flow at the distal of the V3 segment, he decided to sacrifice this artery by two coils. Conclusion: Penetrating neck injuries are usually asymptomatic, but these injuries are often accompanied by hemorrhage, neurological symptoms, dysphagia, odynophagia, and windpipe. Penetrating lesions of the vertebral artery are rare and very difficult to diagnose. Also, these lesions are challenging for surgeons due to complex anatomy and difficult surgical exposure. So, endovascular treatment was used to treat the patient. 展开更多
关键词 penetrating trauma Delayed Pseudoaneurysms Vertebral Artery
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Effect of corneal graft diameter on therapeutic penetrating keratoplasty for fungal keratitis 被引量:5
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作者 Cui Li Gui-Qiu Zhao +6 位作者 Cheng-Ye Che Jing Lin Na Li Wen-Yan Jia Qiu-QiuZhang Nan Jiang Li-Ting Hu 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2012年第6期698-703,共6页
AIM: To evaluate the effect of corneal graft diameter on therapeutic penetrating keratoplasty(PKP) for fungal keratitis. METHODS: A total of 116 patients (116 eyes) suffered from fungal keratitis underwent PKP at the ... AIM: To evaluate the effect of corneal graft diameter on therapeutic penetrating keratoplasty(PKP) for fungal keratitis. METHODS: A total of 116 patients (116 eyes) suffered from fungal keratitis underwent PKP at the Affiliated Hospital of Medical College Qingdao University from May 2006 to May 2010. They were divided into two groups according to the corneal graft diameter. 64 eyes' corneal graft diameter was 8.00mm or larger and 52 eyes' graft diameter was smaller than 8.00mm. The follow-up time was 2 years. The postoperative visual acuity and complications were documented and compared. RESULTS: Sixty-two (96.88%) eyes and fifty (96.15%) eyes preserved eyeballs respectively in two groups. There was no statistical difference in postoperative visual acuity (P =0.961), corneal graft clear rate (P =0.132) or the incidence of recurred fungal infection (P =0.770) between two groups. But there was a higher incidence of graft rejection (P =0.020) and secondary glaucoma (P =0.039) in group with corneal graft diameter 8.00mm or larger. CONCLUSION: PKP is an effective treatment approach for fungal keratitis. There is a higher incidence of complications in large-diameter PKP for fungal keratitis.Effective, preventive and therapeutic measures can improve the prognosis. 展开更多
关键词 KERATOPLASTY penetrating eye infection FUNGAL corneal GRAFT
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Cerebral Fat Embolism Syndrome from Penetrating Trauma: A Rare Cause-and-Effect 被引量:1
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作者 Stephen J. Gleich James D. Hannon 《Open Journal of Anesthesiology》 2013年第4期228-232,共5页
A 42 year-old male sustained an accidental rifle gunshot wound to his left foot, resulting in fracture deformities of the calcaneus, navicular, cuneiform, 1st and 2nd metatarsal bases, and talus. As he was transported... A 42 year-old male sustained an accidental rifle gunshot wound to his left foot, resulting in fracture deformities of the calcaneus, navicular, cuneiform, 1st and 2nd metatarsal bases, and talus. As he was transported to our trauma center, he developed progressive encephalopathy. Urgent external fixator placement under general anesthesia was postponed due to his encephalopathy of unknown etiology. Brain magnetic resonance imaging demonstrated a “starfield” pattern of infarcts, consistent with cerebral fat embolism syndrome. Subsequently, he underwent uneventful general anesthesia. The patient was managed supportively and continued to have persistent neurologic dysfunction two months after injury. 展开更多
关键词 penetrating trauma CEREBRAL FAT EMBOLISM Syndrome
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Management and outcome of bronchial trauma due to blunt versus penetrating injuries 被引量:1
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作者 Jin-Mou Gao Hui Li +5 位作者 Ding-Yuan Du Jun Yang Ling-Wen Kong Jian-Bai Wang Ping He Gong-Bin Wei 《World Journal of Clinical Cases》 SCIE 2022年第16期5185-5195,共11页
BACKGROUND The number of patients with bronchial trauma(BT)who survived to hospital admission has increased with the improvement of prehospital care;early diagnosis and treatment should be considered,especially among ... BACKGROUND The number of patients with bronchial trauma(BT)who survived to hospital admission has increased with the improvement of prehospital care;early diagnosis and treatment should be considered,especially among blunt trauma patients,whose diagnosis is frequently delayed.AIM To describe the early recognition and surgical management considerations of blunt and penetrating BTs,and to elaborate the differences between them.METHODS All patients with BTs during the past 15 years were reviewed,and data were retrospectively analyzed regarding the mechanism of injury,diagnostic and therapeutic procedures,and outcomes.According to the injury mechanisms,the patients were divided into two groups:Blunt BT(BBT)group and penetrating BT(PBT)group.The injury severity,treatment procedures,and prognoses of the two groups were compared.RESULTS A total of 73 patients with BT were admitted during the study period.The proportion of BTs among the entire cohort with chest trauma was 2.4%(73/3018),and all 73 underwent thoracotomy.Polytrauma patients accounted for 81.6% in the BBT group and 22.9%in the PBT group,and the mean Injury Severity Score was 38.22±8.13 and 21.33±6.12,respectively.Preoperative three-dimensional spiral computed tomography(CT)and/or fiberoptic bronchoscopy(FB)were performed in 92.1% of cases in the BBT group(n=38)and 34.3% in the PBT group(n=35).In the BBT group,a delay in diagnosis for over 48 h occurred in 55.3% of patients.In the PBT group,31 patients underwent emergency thoracotomy due to massive hemothorax,and BT was confirmed during the operation.Among them,22 underwent pulmo-tractotomy for hemostasis,avoiding partial pneumonectomy.In this series,the overall mortality rate was 6.9%(5/73),and it was 7.9%(3/38)and 5.7%(2/35)in the BBT group and PBT group,respectively(P>0.05).All 68 survivors were followed for 6 to 42(23±6.4)mo,and CT,FB,and pulmonary function examinations were performed as planned.All patients exhibited normal lung function and healthy conditions except three who required reoperations.CONCLUSION The difference between blunt and penetrating BTs is obvious.In BBT,patients generally have no vessel injury,and the diagnosis is easily missed,leading to delayed treatment.The main cause of death is ventilation disturbance due to tension pneumothorax early and refractory atelectasis with pneumonia late.However,in PBT,most patients require emergency thoracotomy because of simultaneous vessel trauma and massive hemothorax,and delays in diagnosis are infrequent.The leading cause of death is hemorrhagic shock. 展开更多
关键词 Bronchial trauma Bronchial repair BLUNT penetrating ATELECTASIS PNEUMONECTOMY
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Accelerated versus standard corneal cross linking in the treatment of ectasia post refractive surgery and penetrating keratoplasty: a medium term randomized trial
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作者 Hany A.Khairy Moataz F.Elsawy +2 位作者 Khaled Said-Ahmed Marwa A.Zaki Sameh S Mandour 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2019年第11期1714-1719,共6页
AIM: To compare the clinical outcomes of the standard corneal cross linking(CXL) and the accelerated CXL in patients with progressive corneal ectasia post refractive surgery and penetrating keratoplasty.METHODS: Total... AIM: To compare the clinical outcomes of the standard corneal cross linking(CXL) and the accelerated CXL in patients with progressive corneal ectasia post refractive surgery and penetrating keratoplasty.METHODS: Totally 120 eyes of 83 patients scheduled to receive either standard CXL(3 m W/cm^2 for a period of 30 min) or accelerated CXL(18 m W/cm2 for a period of 5 min). The main outcomes for comparison were the change in: maximum-K reading(K-max), manifest refractive spherical equivalent(SE), central corneal thickness(CCT), and the best corrected distance visual acuity(CDVA).RESULTS: One hundred and eleven eyes completed the study. The main outcome measurement was the K-max reading. Both group showed significant improvement in the value postoperatively at 6 and 12 mo. The mean change in the standard group was 1.21±0.11 D and in the accelerated group was 0.90±0.05 D at the end of 12 mo postoperatively, with no statistically significant difference between the 2 groups. Similarly, CDVA improved significantly from their preoperative value in the standard group by 2.98±0.11 letters, and in the accelerated group by 2.20±0.06 letters, with no statistically significant difference between the two groups. Both of the SE, and CCT showed no statistically significant difference at the end of follow up period in each group.CONCLUSION: Both standard CXL and accelerated CXL are safe and effective treatment in halting ectasia after corneal refractive surgery. The accelerated CXL results are comparable to the standard CXL with short time exposure of the cornea to ultraviolet irradiation, leading to reduced operation time, reduced operative ocular discomfort, and corneal haze. 展开更多
关键词 corneal cross LINKING ACCELERATED refractivesurgery penetrating KERATOPLASTY corneal ECTASIA
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Black diaphragm intraocular lens implantation and penetrating keratoplasty in aphakic eyes with traumatic aniridia
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作者 Jun Li Xiao-Guang Dong 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2013年第2期183-186,共4页
AIM:To evaluate the long-term outcome of implantation of black diaphragm intraocular (BDI) lens combined with penetrating keratoplasty (PKP) for managing aphakic eyes with traumatic aniridia and corneal damage. METHOD... AIM:To evaluate the long-term outcome of implantation of black diaphragm intraocular (BDI) lens combined with penetrating keratoplasty (PKP) for managing aphakic eyes with traumatic aniridia and corneal damage. METHODS: Six aphakic eyes of six patients with traumatic aniridia and corneal damage had BDI lens implantation at Qingdao Eye Hospital, Shandong Eye Institute from June 2008 to November 2011. Medical records of the patients were reviewed. Three patients received PKP and after 12-18months were implanted with BDI lens. The other three patients completed PKP and BDI lens implantation at the same time. The corrected visual acuity, intraocular pressure and number of corneal endothelial cells were monitored. RESULTS: The patients were followed up for an average of 24.3 ±12.1months (range 14-48 months). All BDI lenses were located well. The best corrected visual acuity got improved in 5 patients (0.1-1.0) and decreased in 1 patient from 0.4 to 0.2. Three patients had normal intraocular pressure (IOP) after implantation. Two patients required antiglaucoma medications to control IOP within the normal range and 1 patient implanted Ahmed glaucoma valve to control IOP. The corneal grafts kept transparent in all eyes and the corneal endothelial counting >1 000/mm2 , although two patients experienced acute graft rejection and loss more than 30% corneal endothelial cells.CONCLUSION: Implantation of BDI lens combined with PKP is an effective option for managing aphakic eyes with traumatic aniridia and corneal damage. Although the results in our study are encouraging, additional studies of the long -term safety and efficacy are required. Alarger study population and longer follow-up may be beneficial. 展开更多
关键词 BLACK DIAPHRAGM INTRAOCULAR lens penetrating KERATOPLASTY ANIRIDIA trauma
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Penetrating Trauma Resulting in Ventricular Septal Defect
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作者 Daniel Juneau Daniel Hermann Gretchen L. Wells 《World Journal of Cardiovascular Surgery》 2014年第5期77-80,共4页
Most ventricular septal defects (VSDs) are congenital. Acquired VSDs are generally due to myocardial infarction. An unusual case of VSD from penetrating trauma is described. In this case, the lack of a hemopericardium... Most ventricular septal defects (VSDs) are congenital. Acquired VSDs are generally due to myocardial infarction. An unusual case of VSD from penetrating trauma is described. In this case, the lack of a hemopericardium at presentation led the treatment team not to pursue cardiac pathology. Once the patient developed heart failure, the diagnosis of a VSD was made. Patients with penetrating chest wounds should undergo echocardiography, as such lesions may not be detected by physical examination or chest exploration. 展开更多
关键词 VENTRICULAR SEPTAL DEFECT penetrating trauma ECHOCARDIOGRAPHY
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Penetrating Abdominal Trauma: Experience in A Teaching Hospital, Calabar, Southern Nigeria
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作者 Maurice Asuquo Mark Umoh +3 位作者 Victor Nwagbara Gabriel Ugare Cyril Agbor Emmanuel Japhet 《International Journal of Clinical Medicine》 2012年第5期426-430,共5页
Background: Penetrating abdominal trauma (PAT) typically involves the violation of the abdominal cavity by a gun-shot wound (GSW) or stab wound Recently several studies have favored a more conservative approach as opp... Background: Penetrating abdominal trauma (PAT) typically involves the violation of the abdominal cavity by a gun-shot wound (GSW) or stab wound Recently several studies have favored a more conservative approach as opposed to mandatory exploratory laparotomy. Methods: Patients admitted in the University of Calabar Teaching Hospital (UCTH), Calabar, with PAT from January 2008 to December 2010 were prospectively studied based on a questionnaire. The total number of patients with PAT was compared with total number of emergencies, traumatic injuries and abdominal trauma seen during the same period. Results: A total of 48 patients presented with abdominal trauma: PAT 29 (60%) and blunt abdominal trauma (BAT) 19 (40%). The ages of the patients (28 male, 1 female) ranged from 3 - 62 years (mean 28.1 years). Gunshot wound (GSW) 11 (38%) patients, stab wound 8 (27.6%) patients and machete cut 4 (13.8%) patients ranked first, second and third respectively as causes of PAT. The commonest organ injury was perforation of the small intestine. Four (13.8%) patients were managed conservatively while 25 (86.2%) patients had laparotomy. The duration of admission ranged from 2 - 19 days (mean 10.5 days). Morbidity [surgical site infection (SSI)] and mortality were recorded in 2 (6.9%) and 3 (10.3%) patients respectively. Conclusion: Key areas that require attention have been highlighted. Revamping the ailing economy and gainful employment for youths are paramount areas that require prompt, dedicated and sustained intervention for reduction in violent crimes. 展开更多
关键词 penetrating ABDOMINAL trauma Pattern Management
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Penetrating keratoplasty in children under 3 years old with congenital corneal opacities
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作者 Made Susiyanti Burhana Mawarasti Florence M.Manurung 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2022年第1期45-51,共7页
AIM:To evaluate the graft rejection and visual outcomes after penetrating keratoplasty(PK)in the presence of various congenital corneal opacities in children.METHODS:In this retrospective cohort study,children who und... AIM:To evaluate the graft rejection and visual outcomes after penetrating keratoplasty(PK)in the presence of various congenital corneal opacities in children.METHODS:In this retrospective cohort study,children who underwent PK were then followed for 5 y.The patient’s medical records were collected from June 2014 until June 2019 and analyzed in December 2019.All patients were children under three years old with congenital corneal opacities with or without microcornea who came to a pediatric ophthalmologist and underwent PK in Jakarta Eye Center(JEC).Beforehand,all children have participated in a thorough evaluation for PK.In the case of severe microcornea was not advised to undergo surgery.The visual outcomes and graft survival rate were described in percentages.The graft survival plot was presented with Kaplan-Meier,while the visual acuity was analyzed using the Wilcoxon signed ranks test.RESULTS:Sixteen eyes from eleven patients(seven girls and four boys)underwent PK.The graft survival rate of the first 6,12,and 18 mo later of keratoplasty was 100%,83.3%,and 66.7%,respectively.The overall mean survival time is 22 mo(standard error 2.419),and no significant difference between the patients underwent PK before and after 36 mo of their age(P=0.52).The graft failure was 50%,and postsurgery complications included cataract 43.7%,band keratopathy 12.5%,and scleromalasia 6.25%.Wilcoxon test analysis of visual acuity post keratoplasty was not statistically significant(P=0.34),while overall showed 44%improvements of visual outcome for 5 y of follow-up.With a good survival at one year up to 22 mo(83.3%),the visual acuity could be achieved(63%),and showed improvements(44%)during follow-up.CONCLUSION:The complications are frequent for pediatric PK.Thus,corneal surgery on infants requires careful case selection,adequate pre-operative evaluation,skilled surgery(optical correction),very close cooperation family–physician,intensive post-operation care,and amblyopia management in the future. 展开更多
关键词 pediatric penetrating keratoplasty congenital corneal opacities MICROCORNEA CHILDREN
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Contralateral hemopneumothorax after penetrating thoracic trauma:A case report
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作者 Mehlikaİşcan 《World Journal of Clinical Cases》 SCIE 2021年第15期3773-3778,共6页
BACKGROUND Trauma is the leading cause of death in young adults up to the age of 45 years.Hemothorax is a frequent consequence of penetrating thoracic trauma,and is usually associated with pneumothorax and pneumoderma... BACKGROUND Trauma is the leading cause of death in young adults up to the age of 45 years.Hemothorax is a frequent consequence of penetrating thoracic trauma,and is usually associated with pneumothorax and pneumoderma.Intercostal arterial bleeding or intrathoracic hemorrhage occurs after penetrating thoracic trauma,and uncontrolled bleeding is the main cause of death.CASE SUMMARY In this case report,a patient who developed a right hemopneumothorax after penetrating thoracic trauma was examined.A 19-year-old male patient,who was brought to the emergency room with a penetrating stab injury to the posterior of the left hemithorax,was diagnosed with a right hemopneumothorax after physical examination and thoracic imaging.Chest tube thoracostomy was performed as the initial intervention.Bleeding control was achieved with right posterolateral thoracotomy in the patient,who developed massive hemorrhage after 1 h and hemodynamic instability.The patient recovered and was discharged on the fourth postoperative day.CONCLUSION Contralateral hemopneumothorax that accounts for 30%of thoracic traumas and can be encountered in penetrating thoracic traumas requiring major surgery in 15-30%of cases was emphasized and the contralateral development mechanism was addressed. 展开更多
关键词 Chest tube Contralateral hemopneumothorax penetrating thoracic trauma THORACOTOMY Thoracic surgery Tube thoracostomy Case report
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Evaluation of traumatic retinopathy with ultra-wide field imaging under corneal scar or fixed small pupil
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作者 Min Tang Yan-Nian Hui +4 位作者 You-Yi Li Yue He Yang Cao Xiao-Hong Xiang Hong-Bin Lyu 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2018年第8期1371-1376,共6页
AIM: To evaluate the value of ultra-wide field(UWF) imaging in the management of traumatic retinopathy under the condition of corneal scar or fixed small pupil after complicated ocular trauma. METHODS: Twenty-eight pa... AIM: To evaluate the value of ultra-wide field(UWF) imaging in the management of traumatic retinopathy under the condition of corneal scar or fixed small pupil after complicated ocular trauma. METHODS: Twenty-eight patients(28 eyes) with complicated ocular trauma were enrolled in the study from June 2016 to May 2017, including 19 males and 9 females with age ranged from 11 to 64(43.42±12.62)y. All patients were treated with secondary vitrectomy after emergency operation for wound repair of open ocular trauma. Direct ophthalmoscopy and 45-degree fundus photography were taken at each time point of follow up for comparison of findings with UWF images. Routine eye examination including visual acuity, intraocular pressure, slit lamp examination were performed and analyzed as well.RESULTS: Among the 28 traumatized eyes, the positive rate for identification of traumatic retinopathed was 32.1%(9 cases), 14.9%(5 cases), and 85.7%(24 cases) with direct ophthalmoscopy, 45-degree fundus photography, and UWF imaging, respectively. The detective rate of UWF imaging under the condition of corneal scar or fixed small pupil was statistically greater than that of 45-degree fundus photography and direct ophthalmoscopy(Bonferroni correction, P<0.001). UWF image was obtained in 19 eyes with opaque corneal scar, otherwise their fundus could not be seen by conventional methods. The additional findings of traumatic retinopathies by UWF imaging included periretinal membranes or pre-retinal proliferating strip, retinal holes, hemorrhage in the vitreous or sub-retinal space.CONCLUSION: UWF imaging is superior to traditional fundus photography in the evaluation of traumatic retinopathies under the condition of corneal scar or fixed small pupil after complicated ocular trauma. 展开更多
关键词 ultra-wide field imaging complicated ocular trauma corneal scar fixed small pupil fundus photography traumatic retinopathy
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Simultaneous tectonic Descemet stripping endothelial keratoplasty and tectonic Bowman layer transplant for the management of corneal perforation
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作者 Abdo Karim Tourkmani Colm McAlinden +2 位作者 David F.Anderson Jorge L.Alio del Barrio Jorge L.Alió 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2023年第9期1549-1554,共6页
AIM:To report the outcomes of three cases of corneal perforation managed with simultaneous tectonic Descemet stripping endothelial keratoplasty(t-DSEK)and tectonic Bowman layer transplant(t-BLT)as an alternative to te... AIM:To report the outcomes of three cases of corneal perforation managed with simultaneous tectonic Descemet stripping endothelial keratoplasty(t-DSEK)and tectonic Bowman layer transplant(t-BLT)as an alternative to tectonic penetrating keratoplasty(t-PKP).METHODS:Three eyes of three patients receiving simultaneous t-DSEK and t-BLT for corneal perforation were included.The technique for DSEK was modified depending on individual requirements.The t-BLT technique was standardised using an 8 mm graft and fixated with a running suture.Success was measured by the ability of this procedure to close a corneal perforation.RESULTS:All three cases achieved tectonic eye globe restoration and remained stable during the minimum 3-month observation period.Reinterventions were relatively common:2 cases required amniotic membrane transplant for persistent epithelial defects.One case required DSEK rebubbling.One case developed angle closure glaucoma requiring surgical peripheral iridectomy.CONCLUSION:Simultaneous t-DSEK and t-BLT may be a useful strategy for the management of corneal perforation as an alternative management to t-PKP for selected cases. 展开更多
关键词 tectonic corneal graft Descemet stripping endothelial keratoplasty Bowman layer transplant penetrating keratoplasty
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Frontal penetrating arrow injury:A case report
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作者 Alejandra Rodríguez-Ramos Carlos A Zapata-Castilleja +5 位作者 José L Treviño-González Gerardo C Palacios-Saucedo Ramón G Sánchez-Cortés Leonor G Hinojosa-Amaya Adriana Nieto-Sanjuanero Manuel de la O-Cavazos 《World Journal of Clinical Cases》 SCIE 2023年第17期4117-4122,共6页
BACKGROUND Penetrating arrow injuries of the head and neck are exceedingly rare in pediatric patients.This pathology has high morbidity and mortality because of the presence of vital organs,the airway,and large vessel... BACKGROUND Penetrating arrow injuries of the head and neck are exceedingly rare in pediatric patients.This pathology has high morbidity and mortality because of the presence of vital organs,the airway,and large vessels.Therefore,the treatment and removal of an arrow is a challenge that requires multidisciplinary management.CASE SUMMARY A 13-year-old boy was brought to the emergency room after an arrow injury to the frontal region.The arrowhead was lodged in the oropharynx.Imaging studies showed a lesion of the paranasal sinuses without compromising vital structures.The arrow was successfully removed by retrograde nasoendoscopy without complications,and the patient was discharged.CONCLUSION Although rare,maxillofacial arrow injuries have high morbidity and mortality and require multidisciplinary management to preserve function and aesthetics. 展开更多
关键词 ARROW penetrating trauma Maxillofacial injuries PEDIATRICS Pediatric emergency medicine Case report
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塞来昔布固体脂质纳米粒对兔角膜重度热烧伤行穿透性角膜移植术后CNV、MMP-2的影响
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作者 贾雍 张百珂 +2 位作者 郭丽莎 李巧云 田学敏 《联勤军事医学》 CAS 2024年第2期99-104,共6页
目的观察塞来昔布(celecoxib,CXB)固体脂质纳米粒(solid lipid nanoparticles,SLN)对兔角膜重度热烧伤(severe corneal thermal burn,SCTB)行穿透性角膜移植术(penetrating keratoplasty,PKP)后角膜新生血管(corneal neovascularization... 目的观察塞来昔布(celecoxib,CXB)固体脂质纳米粒(solid lipid nanoparticles,SLN)对兔角膜重度热烧伤(severe corneal thermal burn,SCTB)行穿透性角膜移植术(penetrating keratoplasty,PKP)后角膜新生血管(corneal neovascularization,CNV)及基质金属蛋白酶2(matrix metalloproteinase-2,MMP-2)浓度的影响,探讨CXB-SLN对兔SCTB的作用机制。方法取36只新西兰白兔,恒温烧灼器制作兔SCTB模型(左眼),随机分为对照组、PKP组、CXB-PKP组,每组12只。对照组、PKP组球结膜下注射9 g/L的生理盐水0.1 ml,CXB-PKP组球结膜下注射1 g/L的CXB-SLN 0.1 ml。PKP组、CXB-PKP组于造模后第3天行PKP治疗。观察3组白兔术后角膜一般情况并记录术后10、20、40天CNV面积。在术后20、40天各组随机选择6只兔处死。采用酶联免疫吸附试验(enzyme-linked immunosorbent assay,ELISA)检测角膜上清液中MMP-2浓度,并分析CNV面积与MMP-2的相关性。结果术前3组白兔角膜均可见角膜缘充血明显,角膜烧伤区水肿,混浊,伴角膜上皮层坏死、剥脱。术后对照组可见角膜混浊逐渐加重呈瓷白色混浊,PKP组与CXB-PKP组可见角膜植片均成活,角膜透明度尚可。术后10、20、40天,CXB-PKP组CNV面积小于PKP组(P均<0.05),PKP组CNV面积小于对照组(P均<0.05)。术后20和40天角膜上清液MMP-2的浓度,CXB-PKP组低于PKP组,PKP组低于对照组(P均<0.05)。术后20、40天,CNV面积与MMP-2浓度呈正相关(r=0.742,P<0.001;r=0.827,P<0.001)。结论CXB-SLN对兔SCTB后的CNV具有明显抑制作用,可减轻角膜混浊,其机理可能与MMP-2的下调有关,能够为SCTB后行PKP创造有利条件。 展开更多
关键词 塞来昔布 固体脂质纳米粒 角膜重度热烧伤 穿透性角膜移植术 角膜新生血管 基质金属蛋白酶2
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Outcome analysis of management of liver trauma: A 10-year experience at a trauma center 被引量:3
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作者 Wong Hoi She Tan To Cheung +5 位作者 Wing Chiu Dai Simon HY Tsang Albert CY Chan Daniel KH Tong Gilberto KK Leung Chung Mau Lo 《World Journal of Hepatology》 CAS 2016年第15期644-648,共5页
AIM: To review the outcomes of liver trauma in patients with hepatic injuries only and in patients with associated injuries outside the liver.METHODS: Data of liver trauma patients presented to our center from January... AIM: To review the outcomes of liver trauma in patients with hepatic injuries only and in patients with associated injuries outside the liver.METHODS: Data of liver trauma patients presented to our center from January 2003 to October 2013 were reviewed. The patients were divided into two groups. Group 1 consisted of patients who had hepatic injuries only. Group 2 consisted of patients who also had associated injuries outside the liver.RESULTS: Seven(30.4%) patients in group 1 and 10(28.6%) patients in group 2 received non-operative management; the rest underwent operation. Blunt trauma occurred in 82.8%(48/58) of the patients and penetrative trauma in 17.2%(10/58). A higher injury severity score(ISS) was observed in group 2(median 45 vs 25, P < 0.0001). More patients in group 1 were hemodynamically stable(65.2% vs 37.1%, P = 0.036). Other parameters were comparable between groups. Group 1 had better 30-d survival(91.3% vs 71.4%, P = 0.045). On multivariate analysis using the logistic regression model, ISS was found to be associated with mortality(P = 0.004, hazard ratio = 1.035, 95%CI:CONCLUSION: Liver trauma patients with multiple injuries are relatively unstable on presentation. Despite a higher ISS in group 2, non-operative management was possible for selected patients. Associated injuries outside the liver usually account for morbidity and mortality. 展开更多
关键词 NON-OPERATIVE MANAGEMENT LIVER trauma Multiple injuries Penetrative trauma LIVER LACERATION BLUNT tr
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Morphometric study of endothelial wound-healing following penetrating keratoplasty 被引量:3
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作者 蒋华 宋振英 林庆华 《Journal of Medical Colleges of PLA(China)》 CAS 1993年第3期291-295,共5页
Twenty samples of endothelia removed from normal and post penetrating keratoplas-ty (0.5,1,2,3 months after penetrating keratoplasty) were observed by scanning electron mi-croscopy.The photographs of the endothelia in... Twenty samples of endothelia removed from normal and post penetrating keratoplas-ty (0.5,1,2,3 months after penetrating keratoplasty) were observed by scanning electron mi-croscopy.The photographs of the endothelia in graft-host junction were analyzed by computer-assisted image analysis system,and the morphometric indexes examined were area of the cells,perimeters,density,figure coefficient,long axis,coefficient of variation of the area,and oth-ers.Results showed that the morphology and the density of the endothelial cells changed obvi-ously after operation and improved slowly but progressively with time although at 3 monthspostoperatively some differences still existed.By using the new techniques,the experiment con-firmed and enriched the theories on the corneal endothelial wound-healing,revealing some ofthe new characters of the endothelial wound-healing following penetrating keratoplasty. 展开更多
关键词 KERATOPLASTY penetrating corneal ENDOTHELIUM wound healing MORPHOMETRY rabbits
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Application of pediatric ocular trauma score in pediatric open globe injuries 被引量:7
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作者 Chao Xue Li-Chun Yang Yi-Chun Kong 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2020年第7期1097-1101,共5页
AIM:To evaluate the predictive value of pediatric penetrating ocular trauma score(POTS)on the visual outcome in children with open globe injury.METHODS:A retrospective study in 90 children(60 males and 30 females)aged... AIM:To evaluate the predictive value of pediatric penetrating ocular trauma score(POTS)on the visual outcome in children with open globe injury.METHODS:A retrospective study in 90 children(60 males and 30 females)aged 1-15 y(average,7.48±2.86 y)with penetrating ocular trauma was performed.Each patient’s POTS was calculated.The effects of POTS on final visual acuity(FVA)were examined.Correlation between factors affecting POTS and the FVA was established.RESULTS:All patients presented with single-eye trauma.The follow-up time was 3-21 mo(average,10.23±3.54 mo).Among the 90 cases of penetrating wounds,71 eyes(78.89%)were injured in Zone I(wound involvement limited to the cornea,including the corneoscleral limbus),17 eyes(18.89%)were injured in Zone II(wound involving the sclera and no more posterior than 5 mm from the corneoscleral limbus),and 2 eyes(2.22%)were injured in Zone III(wound involvement posterior to the anterior 5 mm of the sclera).Analysis of POTS and FVA showed important correlation between them(r=0.414,P=0.000).Initial visual acuity(P=0.00),age(P=0.02),injury location(P=0.002),traumatic cataract(P=0.00),vitreous hemorrhage(P=0.027),retinal detachment(P=0.003),and endophthalmitis(P=0.03)were found to be statistically significant factors for the FVA outcome.CONCLUSION:Ocular trauma presents serious consequences and poor prognosis in children.The POTS may be a reliable prognostic tool in children with open globe injury. 展开更多
关键词 the pediatric penetrating ocular trauma score CHILDREN open globe injury predictive value
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Prevalence and associated factors of corneal blindness in Ningxia in northwest China 被引量:1
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作者 Xun-Lun Sheng Hui-Ping Li +9 位作者 Qing-Xia Liu Wei-Ning Rong Wen-Zhang Du Li Ma Guang-Hui Yan Run-Qing Ma Jian-Ling Zhang Hui-Fang Xu Wen-Qing Zou Xiao-Jun Bi 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2014年第3期557-562,共6页
AIM:To describe the prevalence and demographic characteristics of corneal blindness in an urban and rural region of Ningxia,located in the northwest part of China.METHODS:A stratified,randomized sampling procedure was... AIM:To describe the prevalence and demographic characteristics of corneal blindness in an urban and rural region of Ningxia,located in the northwest part of China.METHODS:A stratified,randomized sampling procedure was employed in the study,including urban and rural area of all age group.Visual acuity,anterior segment and ocular fundus were checked.Related factor of corneal disease,including age,gender,education status,ethnic group,location and occupation,were identified according to uniform customized protocol.An eye was defined to be corneal blindness if the visual acuity was<20/400 due to a corneal disease.RESULTS:Three thousand individuals(1290 from urban area and 1710 from rural area)participated in the investigation,with a response rate of 80.380%.The prevalence of corneal blindness was 0.023%in both eyes and 0.733%in at least one eye.The blindness in at least one eye with varied causes was present in 106participants(3.533%)and in bilateral eyes in 34participants(1.133%).The corneal diseases accounted for 20.754%of blindness in at least one eye and 20.588%of bilateral blindness.The prevalence of corneal disease was higher in older and Han ethnic group,especially those who occupied in agriculture and outdoor work.People with corneal blindness were more likely to be older and lower education.Rural population were more likely to suffer from bilateral corneal blindness than the urban population in≥59-year group(χ2=6.716,P=0.019).Infectious,trauma and immune corneal disease were the three leading causes of corneal disease.Trauma cornealdisease was more likely leading to blindness in one eye.However,infectious and immune corneal diseases make more contribution to the bilateral corneal blindness.CONCLUSION:Corneal blindness is a significant burden of in Ningxia population,encompassing a variety of corneal infections and trauma;the majority of those were avoidable.Health promotion strategies and good hygienic conditions have to be developed. 展开更多
关键词 corneal disease EPIDEMIOLOGY BLINDNESS infectious keratitis trauma
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Hydration with Cefuroxime-a method for sealing a small leaking corneal perforation 被引量:1
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作者 Gilad Allon Itzchak Beiran Eytan Z.Blumenthal 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2016年第5期792-793,共2页
Dear Sir,Iam Dr.Gilad Allon from the Department of Ophthalmology of the Rambam Health Care Campus,Haifa,Israel.I write to present a case report of corneal hydration with Cefuroxime in order to seal a traumatic corneal... Dear Sir,Iam Dr.Gilad Allon from the Department of Ophthalmology of the Rambam Health Care Campus,Haifa,Israel.I write to present a case report of corneal hydration with Cefuroxime in order to seal a traumatic corneal perforation.In the case of a penetrating trauma limited to the cornea,the immediate objective of treatment is to seal the globe and avoid later intraocular infection.Sealing the globe can 展开更多
关键词 corneal PERFORATION HYDRATION INTRAOCULAR traumatic penetrating SEALING Israel write globe
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