Ten neolignans or norlignans(1-10)including eight new compounds were isolated from the whole bodies of Polyphaga plancyi Bolivar.Their structures were identified by spectroscopic data.Compounds 3,4,8,and 9 are racemat...Ten neolignans or norlignans(1-10)including eight new compounds were isolated from the whole bodies of Polyphaga plancyi Bolivar.Their structures were identified by spectroscopic data.Compounds 3,4,8,and 9 are racemates indicated by chiral HPLC analysis.Chiral separation followed by ECD calculations allowed to clarify the absolute configurations of all the antipodes.All the new compounds were evaluated for their biological properties toward extracellular matrix in rat renal proximal tubular cells,human cancer cells(K562,A549,and Huh7),EV71,ROCK2,JAK3,DDR1,and coagulation.展开更多
2012~2014年，采用人工饲养实验观察法辅以野外调查法对中华山蝠（Nyctalus plancyi）冬眠期间生理特性及生态习性进行了初步研究.结果表明：中华山蝠冬眠期从当年的11月开始至翌年的3月结束，平均持续113±15.56 d；整个冬眠期冬眠...2012~2014年，采用人工饲养实验观察法辅以野外调查法对中华山蝠（Nyctalus plancyi）冬眠期间生理特性及生态习性进行了初步研究.结果表明：中华山蝠冬眠期从当年的11月开始至翌年的3月结束，平均持续113±15.56 d；整个冬眠期冬眠阵10.2±3.03个，包含深冬眠阵和短冬眠阵两种形式，冬眠阵平均时长9.87±9.17 d；冬眠时间占整个冬眠期的77%±4.5%.中华山蝠在入眠前会积累大量的脂肪，体重增加到30 g 左右.越冬期内，中华山蝠苏醒状态下的最低环境温度为8℃，当环境温度降低到8℃以下时，全部个体进入冬眠.激醒后由醒到眠的呼吸频率变化很大，可在10 min 内从1225次/ min 下降到7次/ min.展开更多
基金supported by the National Science Fund for Distinguished Young Scholars(81525026)Shenzhen Government’s Plan of Science and Technology(JCYJ20170412110504956).
文摘Ten neolignans or norlignans(1-10)including eight new compounds were isolated from the whole bodies of Polyphaga plancyi Bolivar.Their structures were identified by spectroscopic data.Compounds 3,4,8,and 9 are racemates indicated by chiral HPLC analysis.Chiral separation followed by ECD calculations allowed to clarify the absolute configurations of all the antipodes.All the new compounds were evaluated for their biological properties toward extracellular matrix in rat renal proximal tubular cells,human cancer cells(K562,A549,and Huh7),EV71,ROCK2,JAK3,DDR1,and coagulation.
文摘2012~2014年，采用人工饲养实验观察法辅以野外调查法对中华山蝠（Nyctalus plancyi）冬眠期间生理特性及生态习性进行了初步研究.结果表明：中华山蝠冬眠期从当年的11月开始至翌年的3月结束，平均持续113±15.56 d；整个冬眠期冬眠阵10.2±3.03个，包含深冬眠阵和短冬眠阵两种形式，冬眠阵平均时长9.87±9.17 d；冬眠时间占整个冬眠期的77%±4.5%.中华山蝠在入眠前会积累大量的脂肪，体重增加到30 g 左右.越冬期内，中华山蝠苏醒状态下的最低环境温度为8℃，当环境温度降低到8℃以下时，全部个体进入冬眠.激醒后由醒到眠的呼吸频率变化很大，可在10 min 内从1225次/ min 下降到7次/ min.
