Alzheimer’s disease and related dementias have made a considerable impact on society, and can take a significant toll on familial caregivers. Recent successful caregiving interventions suggest a promising future, tho...Alzheimer’s disease and related dementias have made a considerable impact on society, and can take a significant toll on familial caregivers. Recent successful caregiving interventions suggest a promising future, though informed research design, a priori, is paramount in ensuring quality results that the Government and public may use to make informed policy and personal healthcare decisions. Research designs including basic science, randomized controlled trials (RCTs), qualitative, and quasi-experimental designs serve as the primary basis for discussion with literary examples and caveats.展开更多
To present the advances of evidence-based medicine and clinical research methodology in integrative oncology,we conducted a literature review of real-world studies of traditional Chinese medicine(TCM)in cancer care an...To present the advances of evidence-based medicine and clinical research methodology in integrative oncology,we conducted a literature review of real-world studies of traditional Chinese medicine(TCM)in cancer care and summarized the available evidence.Pragmatic randomized controlled trials(pRCTs)and clinical registry studies are becoming more popular as they could compensate for the limitations of RCTs.Many RCTs of TCM for cancer treatment as well as systematic reviews have been published.The most investigated therapies are based on acupuncture,Chinese herbal compounds,and Chinese patent medicines.Acupuncture has a significant advantage in relieving cancer-related symptoms.Published studies focus more on improving clinical symptoms and laboratory indicators.However,the patient's quality of life deserves more attention.展开更多
Distributed System Course is a professional computer course of Harbin Institute of Technology.With the guidance of the education strategy under the background of New Engineering,we adhere to the concept of cultivating...Distributed System Course is a professional computer course of Harbin Institute of Technology.With the guidance of the education strategy under the background of New Engineering,we adhere to the concept of cultivating diverse and innovative outstanding engineering and technology talents.This course conducts research on the teaching content,teaching mode,and evaluation system.It combines the traditional teaching mode with the online teaching mode,as well as problem-driven theories with practice,and adopts a diversified evaluation system.The research of the course has fully mobilized students’learning enthusiasm,improved teaching quality,and achieved significant teaching results.展开更多
The results of years of dental study serve as the foundation for the practise of medicine and,for that matter,dentistry.Doctors may have their own preferences for techniques and materials,but whether directly or indir...The results of years of dental study serve as the foundation for the practise of medicine and,for that matter,dentistry.Doctors may have their own preferences for techniques and materials,but whether directly or indirectly,their decisions are influenced by systematic reviews and meta-analyses.However,due to poorly conducted or presented research,this very basic foundation may not be reliable.Bias in research is one of several factors that might make study results or research itself unreliable.Bias can be introduced into research at many stages,deliberately or unknowingly.Bias can appear at any point during the research process,even before the study itself begins.There are many biases in research,but some of them are more relevant to dentistry research than others.Because it is said that“eyes see what the mind knows”,it is essential to have a complete understanding of the different types of bias,how and when they get entrenched,and what steps may be taken to prevent or lessen them if they do occur.This comprehensive summary of bias in dentistry research is provided by this synoptic review.The goal is to identify gaps and measures that have been taken-or that should have been taken-by providing both descriptive and evaluative summaries,as well as examples from the literature,when needed.展开更多
为更好地了解设计研究领域的发展趋势,掌握设计研究过程的前沿热点,以Web of Science数据库收录的核心期刊Design Studies于2007—2021年发表的论文为例,利用文献计量法和VOSviewer可视化工具对发文国家、文献共被引、研究机构、高产作...为更好地了解设计研究领域的发展趋势,掌握设计研究过程的前沿热点,以Web of Science数据库收录的核心期刊Design Studies于2007—2021年发表的论文为例,利用文献计量法和VOSviewer可视化工具对发文国家、文献共被引、研究机构、高产作者、高频关键词等方面进行分析。结果表明:设计研究领域发展脉络清晰,英国、美国占据主导地位。近年来的研究热点聚焦于设计实践方法、设计交互理念、设计成果评估与设计解决方案创新等方面;而设计方法开发、设计灵感来源及未来服务设计等主题已成为该领域的研究前沿。结合当前国内设计研究领域发展现状,中国学者需适当兼顾国际期刊发表规律,积极促进与设计过程相关的理论开发与应用,在该领域发出更多“中国声音”。展开更多
Matrix multiplication plays a pivotal role in the symmetric cipher algorithms, but it is one of the most complex and time consuming units, its performance directly affects the efficiency of cipher algorithms. Combined...Matrix multiplication plays a pivotal role in the symmetric cipher algorithms, but it is one of the most complex and time consuming units, its performance directly affects the efficiency of cipher algorithms. Combined with the characteristics of VLIW processor and matrix multiplication of symmetric cipher algorithms, this paper extracted the reconfigurable elements and analyzed the principle of matrix multiplication, then designed the reconfigurable architecture of matrix multiplication of VLIW processor further, at last we put forward single instructions for matrix multiplication between 4×1 and 4×4 matrix or two 4×4 matrix over GF(2~8), through the instructions extension, the instructions could support larger dimension operations. The experiment shows that the instructions we designed supports different dimensions matrix multiplication and improves the processing speed of multiplication greatly.展开更多
IPv6 is the foundation of the development of Next Generation Internet (NGI). An IPv6 network management and operations support system is necessary for real operable NGI. Presently there are no approved standards yet a...IPv6 is the foundation of the development of Next Generation Internet (NGI). An IPv6 network management and operations support system is necessary for real operable NGI. Presently there are no approved standards yet and relevant equipment interfaces are not perfect. A Network Management System (NMS) at the network layer helps implement the integrated management of a network with equipment from multiple vendors, including the network resources and topology, end-to-end network performance, network failures and customer Service Level Agreement (SLA) management. Though the NMS will finally realize pure IPv6 network management, it must be accommodated to the management of relevant IPv4 equipment. Therefore, modularized and layered structure is adopted for the NMS in order to implement its smooth transition.展开更多
The technique of cutting slabstone with stone-sawi ng machine is analyzed completely. A new kind of cutting movement trajectory is gi ven whose actual cutting efficiency is near to 100%. It can reduce the energy w ear...The technique of cutting slabstone with stone-sawi ng machine is analyzed completely. A new kind of cutting movement trajectory is gi ven whose actual cutting efficiency is near to 100%. It can reduce the energy w earing greatly, and the surface quality of the product is improved to the utmost extent. The design mechanism of the optimal cutting movement trajectory system structure is analyzed incisively. At the same time, the principle of the complex movement of horizontal movement and swing is researched. The optimal design scheme of th e cutting movement trajectory system structure is set up. The choice method to g et the superior value of the movement system structure is found. The mathematics function formula is established which exhibits the relationship between the par ameter of the complex movement structure and that of the system movement structu re. By the formula, the precision value of the offset can be figured out. The r ule is adapted to different types of energy-saving stone-sawing machines. The complex movement structure of horizontal movement and swing is designed to f ulfill the cutting movement. It can make the saw frame move up with the hanging pod deviating from the vertical direction. At the same time, the saw frame have a down-movement. Then the sum of the two movements is near to zero, and the saw blade and the stone can keep in touch during the whole horizontal cutting. The result is that the actual cutting efficiency is 100%. Also, when the hanging pod moves to the limited position, the saw frame can keep the original inertia, and continue to swing up. It makes the back-cutting have high energy-storing. The optimal design of the eccentricity balance wheel is done. The mathematics fo rmula for expressing the movement system structure is deduced. The calculation m ethod and formula is set up which is used to get the value of important componen ts such as offset. The choice method and formula of elasticity distortion coeffi cient is set up when the saw frame moves smoothly. It is concluded that the offs et is the key dimension to actualize the optimal cutting movement trajectory. The resolving of the technical problems discussed above offers a theoretic and technical basis for optimal design of energy-saving stone-sawing machines.展开更多
The automotive seat market is positioned to significantly grow over the next five years. Research into how sensor implementation in every day driver cars can enhance driver wellness is becoming increasingly popular an...The automotive seat market is positioned to significantly grow over the next five years. Research into how sensor implementation in every day driver cars can enhance driver wellness is becoming increasingly popular and visible in the automotive seat industry. However, in the competitive race car industry,?drivers prioritize driving ability over wellness. To further examine this phenomenon, the Human-Machine Interaction?Lab at the Georgia Institute of Technology took a unique approach to developing strong use cases for implementing sensor technology to improve driving ability for race car drivers by combining qualitative and quantitative research data obtained through modern design research and planning methodology. Following a process relying heavily on user-centered design methods, the authors developed a business case concept?for?a sensor-based seat accessory that acts as a competitive racer’s?driving coach?that is able to identify the mechanics of braking, turning, and accelerating through pressure sensors in the driver’s seat pan surface. This technology allows drivers to precisely understand when and how hard to brake, turn, or accelerate out of turns, thus reducing heat times and financial burden for drivers.展开更多
Safety systems, built on state-of-the-art technology, are essential for achieving acceptable levels of plant safety to minimize hazards to the reactor and the general public. The second shutdown system(SSS) as an engi...Safety systems, built on state-of-the-art technology, are essential for achieving acceptable levels of plant safety to minimize hazards to the reactor and the general public. The second shutdown system(SSS) as an engineered safety feature and a part of the reactor protection system(RPS) is a means for rapidly shutting down a nuclear reactor, keeping it in a subcritical state and serving as a backup to the first shutdown system(FSS). In this research, one SSS with two types of optimum chamber designs is proposed that take into account the main current characteristic features of the Tehran research reactor with improvements over earlier designs. They are based on a liquid neutron absorber injection that is preferably different, diverse, and independent from the FSS based on the rod drop mechanism. The major design characteristics of this SSS with two different chambers were investigated using MCNPX 2.6.0 code. The performed calculations showed that the designed SSS is a reliable shutdown system, assuring an appropriate shutdown margin and injection time, with no significant effects on the effective delayed neutron fraction while causing minimal variations to the core structure. Further, the reasonable financial cost and the prolongation of the operation cycle are additional advantages of this design.展开更多
The retrospective study by Lei et al is an investigation of the relationship between age and subfoveal choroidal thickness(SFCT)in Chinese patients with proliferative diabetic retinopathy.Elements of the study design ...The retrospective study by Lei et al is an investigation of the relationship between age and subfoveal choroidal thickness(SFCT)in Chinese patients with proliferative diabetic retinopathy.Elements of the study design prevent the generalizability of the study findings,limiting their clinical implications.We recommend consideration of stricter eligibility criteria,other variables like duration of diabetes,interpretation of gender-differences in SFCT,longitudinal follow-up,use of newer choroidal flow indices,comparison of values with normal controls,subgroup analysis to determine the effect of prior treatment,as well as consideration of various real-world scenarios in future studies.展开更多
文摘Alzheimer’s disease and related dementias have made a considerable impact on society, and can take a significant toll on familial caregivers. Recent successful caregiving interventions suggest a promising future, though informed research design, a priori, is paramount in ensuring quality results that the Government and public may use to make informed policy and personal healthcare decisions. Research designs including basic science, randomized controlled trials (RCTs), qualitative, and quasi-experimental designs serve as the primary basis for discussion with literary examples and caveats.
基金This study was supported by the Key Project of the National Natural Science Foundation of China(81830115).
文摘To present the advances of evidence-based medicine and clinical research methodology in integrative oncology,we conducted a literature review of real-world studies of traditional Chinese medicine(TCM)in cancer care and summarized the available evidence.Pragmatic randomized controlled trials(pRCTs)and clinical registry studies are becoming more popular as they could compensate for the limitations of RCTs.Many RCTs of TCM for cancer treatment as well as systematic reviews have been published.The most investigated therapies are based on acupuncture,Chinese herbal compounds,and Chinese patent medicines.Acupuncture has a significant advantage in relieving cancer-related symptoms.Published studies focus more on improving clinical symptoms and laboratory indicators.However,the patient's quality of life deserves more attention.
文摘Distributed System Course is a professional computer course of Harbin Institute of Technology.With the guidance of the education strategy under the background of New Engineering,we adhere to the concept of cultivating diverse and innovative outstanding engineering and technology talents.This course conducts research on the teaching content,teaching mode,and evaluation system.It combines the traditional teaching mode with the online teaching mode,as well as problem-driven theories with practice,and adopts a diversified evaluation system.The research of the course has fully mobilized students’learning enthusiasm,improved teaching quality,and achieved significant teaching results.
文摘The results of years of dental study serve as the foundation for the practise of medicine and,for that matter,dentistry.Doctors may have their own preferences for techniques and materials,but whether directly or indirectly,their decisions are influenced by systematic reviews and meta-analyses.However,due to poorly conducted or presented research,this very basic foundation may not be reliable.Bias in research is one of several factors that might make study results or research itself unreliable.Bias can be introduced into research at many stages,deliberately or unknowingly.Bias can appear at any point during the research process,even before the study itself begins.There are many biases in research,but some of them are more relevant to dentistry research than others.Because it is said that“eyes see what the mind knows”,it is essential to have a complete understanding of the different types of bias,how and when they get entrenched,and what steps may be taken to prevent or lessen them if they do occur.This comprehensive summary of bias in dentistry research is provided by this synoptic review.The goal is to identify gaps and measures that have been taken-or that should have been taken-by providing both descriptive and evaluative summaries,as well as examples from the literature,when needed.
文摘为更好地了解设计研究领域的发展趋势,掌握设计研究过程的前沿热点,以Web of Science数据库收录的核心期刊Design Studies于2007—2021年发表的论文为例,利用文献计量法和VOSviewer可视化工具对发文国家、文献共被引、研究机构、高产作者、高频关键词等方面进行分析。结果表明:设计研究领域发展脉络清晰,英国、美国占据主导地位。近年来的研究热点聚焦于设计实践方法、设计交互理念、设计成果评估与设计解决方案创新等方面;而设计方法开发、设计灵感来源及未来服务设计等主题已成为该领域的研究前沿。结合当前国内设计研究领域发展现状,中国学者需适当兼顾国际期刊发表规律,积极促进与设计过程相关的理论开发与应用,在该领域发出更多“中国声音”。
基金supported in part by open project foundation of State Key Laboratory of Cryptology National Natural Science Foundation of China (NSFC) under Grant No. 61272492, No. 61572521 and No. 61309008Natural Science Foundation for Young of Shaanxi Province under Grant No. 2013JQ8013
文摘Matrix multiplication plays a pivotal role in the symmetric cipher algorithms, but it is one of the most complex and time consuming units, its performance directly affects the efficiency of cipher algorithms. Combined with the characteristics of VLIW processor and matrix multiplication of symmetric cipher algorithms, this paper extracted the reconfigurable elements and analyzed the principle of matrix multiplication, then designed the reconfigurable architecture of matrix multiplication of VLIW processor further, at last we put forward single instructions for matrix multiplication between 4×1 and 4×4 matrix or two 4×4 matrix over GF(2~8), through the instructions extension, the instructions could support larger dimension operations. The experiment shows that the instructions we designed supports different dimensions matrix multiplication and improves the processing speed of multiplication greatly.
文摘IPv6 is the foundation of the development of Next Generation Internet (NGI). An IPv6 network management and operations support system is necessary for real operable NGI. Presently there are no approved standards yet and relevant equipment interfaces are not perfect. A Network Management System (NMS) at the network layer helps implement the integrated management of a network with equipment from multiple vendors, including the network resources and topology, end-to-end network performance, network failures and customer Service Level Agreement (SLA) management. Though the NMS will finally realize pure IPv6 network management, it must be accommodated to the management of relevant IPv4 equipment. Therefore, modularized and layered structure is adopted for the NMS in order to implement its smooth transition.
文摘The technique of cutting slabstone with stone-sawi ng machine is analyzed completely. A new kind of cutting movement trajectory is gi ven whose actual cutting efficiency is near to 100%. It can reduce the energy w earing greatly, and the surface quality of the product is improved to the utmost extent. The design mechanism of the optimal cutting movement trajectory system structure is analyzed incisively. At the same time, the principle of the complex movement of horizontal movement and swing is researched. The optimal design scheme of th e cutting movement trajectory system structure is set up. The choice method to g et the superior value of the movement system structure is found. The mathematics function formula is established which exhibits the relationship between the par ameter of the complex movement structure and that of the system movement structu re. By the formula, the precision value of the offset can be figured out. The r ule is adapted to different types of energy-saving stone-sawing machines. The complex movement structure of horizontal movement and swing is designed to f ulfill the cutting movement. It can make the saw frame move up with the hanging pod deviating from the vertical direction. At the same time, the saw frame have a down-movement. Then the sum of the two movements is near to zero, and the saw blade and the stone can keep in touch during the whole horizontal cutting. The result is that the actual cutting efficiency is 100%. Also, when the hanging pod moves to the limited position, the saw frame can keep the original inertia, and continue to swing up. It makes the back-cutting have high energy-storing. The optimal design of the eccentricity balance wheel is done. The mathematics fo rmula for expressing the movement system structure is deduced. The calculation m ethod and formula is set up which is used to get the value of important componen ts such as offset. The choice method and formula of elasticity distortion coeffi cient is set up when the saw frame moves smoothly. It is concluded that the offs et is the key dimension to actualize the optimal cutting movement trajectory. The resolving of the technical problems discussed above offers a theoretic and technical basis for optimal design of energy-saving stone-sawing machines.
文摘The automotive seat market is positioned to significantly grow over the next five years. Research into how sensor implementation in every day driver cars can enhance driver wellness is becoming increasingly popular and visible in the automotive seat industry. However, in the competitive race car industry,?drivers prioritize driving ability over wellness. To further examine this phenomenon, the Human-Machine Interaction?Lab at the Georgia Institute of Technology took a unique approach to developing strong use cases for implementing sensor technology to improve driving ability for race car drivers by combining qualitative and quantitative research data obtained through modern design research and planning methodology. Following a process relying heavily on user-centered design methods, the authors developed a business case concept?for?a sensor-based seat accessory that acts as a competitive racer’s?driving coach?that is able to identify the mechanics of braking, turning, and accelerating through pressure sensors in the driver’s seat pan surface. This technology allows drivers to precisely understand when and how hard to brake, turn, or accelerate out of turns, thus reducing heat times and financial burden for drivers.
文摘Safety systems, built on state-of-the-art technology, are essential for achieving acceptable levels of plant safety to minimize hazards to the reactor and the general public. The second shutdown system(SSS) as an engineered safety feature and a part of the reactor protection system(RPS) is a means for rapidly shutting down a nuclear reactor, keeping it in a subcritical state and serving as a backup to the first shutdown system(FSS). In this research, one SSS with two types of optimum chamber designs is proposed that take into account the main current characteristic features of the Tehran research reactor with improvements over earlier designs. They are based on a liquid neutron absorber injection that is preferably different, diverse, and independent from the FSS based on the rod drop mechanism. The major design characteristics of this SSS with two different chambers were investigated using MCNPX 2.6.0 code. The performed calculations showed that the designed SSS is a reliable shutdown system, assuring an appropriate shutdown margin and injection time, with no significant effects on the effective delayed neutron fraction while causing minimal variations to the core structure. Further, the reasonable financial cost and the prolongation of the operation cycle are additional advantages of this design.
文摘The retrospective study by Lei et al is an investigation of the relationship between age and subfoveal choroidal thickness(SFCT)in Chinese patients with proliferative diabetic retinopathy.Elements of the study design prevent the generalizability of the study findings,limiting their clinical implications.We recommend consideration of stricter eligibility criteria,other variables like duration of diabetes,interpretation of gender-differences in SFCT,longitudinal follow-up,use of newer choroidal flow indices,comparison of values with normal controls,subgroup analysis to determine the effect of prior treatment,as well as consideration of various real-world scenarios in future studies.
