Purpose:Diaspora researchers work in one country but have ancestral origins in another,either through moves during a research career(mobile diaspora researchers)or by starting research in the target country(embedded d...Purpose:Diaspora researchers work in one country but have ancestral origins in another,either through moves during a research career(mobile diaspora researchers)or by starting research in the target country(embedded diaspora researchers).Whilst mobile researchers might be tracked through affiliation changes in bibliometric databases,embedded researchers cannot.This article reports an evidence-based discussion of which countries’diaspora researchers can be partially tracked using first or last names,addressing this limitation.Design/methodology/approach:A frequency analysis of first and last names of authors of all Scopus journal articles 2001-2021 for 200 countries or regions.Findings:There are great variations in the extent to which first or last names are uniquely national,from Monserrat(no unique first names)to Thailand(81%unique last names).Nevertheless,most countries have a subset of first or last names that are relatively unique.For the 50 countries with the most researchers,authors with relatively national names are always more likely to research their name-associated country,suggesting a continued national association.Lists of researchers’first and last name frequencies and proportions are provided for 200 countries/regions.Research limitations:Only one period is tracked(2001-2021)and no attempt was made to validate the ancestral origins of any researcher.Practical implications:Simple name heuristics can be used to identify the international spread of a sample of most countries’diaspora researchers,but some manual checks of individual names are needed to weed out false matches.This can supplement mobile researcher data from bibliometric databases.Originality/value:This is the first attempt to list name associations for the authors of all countries and large regions,and to identify the countries for which diaspora researchers could be tracked by name.展开更多
Background:Researchers have a higher risk of anxiety and depression than the general population,so it is important to promote researchers’mental health.Method:Based on the data from 3210 global researchers surveyed b...Background:Researchers have a higher risk of anxiety and depression than the general population,so it is important to promote researchers’mental health.Method:Based on the data from 3210 global researchers surveyed by the journal Nature in 2021,confirmatory factor analysis,OLS regression and other regressions were used to explore the research incentive dimensions and their effects on researchers’mental health.Results:(1)Material incentive factors,work-family life balance factors,good organizational environment and spiritual motivation had significant positive effects on researchers’mental health.(2)The spiritual motivation could better promote researchers’mental health than the other factors.(3)Heterogeneity analysis showed that material incentive factors and spiritual motivation created more significant stimulating effects on the mental health of humanities and social sciences researchers.Work-family life balance factors were more effective in promoting the mental health of the mid-career group and the overtime group.Conclusion:Application of the four research incentives resulted in lower likelihood of anxiety or depression among researchers,and special attention should be paid to the role of the spiritual motivation.In order to promote researchers’mental health,different incentives should be applied to different researcher groups to better improve researchers’mental health.展开更多
BACKGROUND Good clinical practice(GCP)is put in place to protect human participants in clinical trials as well as to ensure the quality of research.Non-adherence to these guidelines can produce research that may not m...BACKGROUND Good clinical practice(GCP)is put in place to protect human participants in clinical trials as well as to ensure the quality of research.Non-adherence to these guidelines can produce research that may not meet the standards set by the scientific community.Therefore,it must be ensured that researchers are wellversed in the GCP.But not much is known about the knowledge and practices of the GCP in the medical colleges of North India.AIM To assess the knowledge and practices of researchers about GCP and analyze these with respect to the demographics of participants.METHODS This is a cross-sectional study.A self-structured questionnaire about GCP,after expert validations,was circulated among researchers,at a tertiary healthcare institute,All India Institute of Medical Sciences(AIIMS),Rishikesh.A total of 59 individuals,who were selected by universal sampling,participated in the study.All healthcare workers who have been investigators of Institutional Ethics Committee-approved research projects,except residents and faculty,and are still a part of the institute have been included in the study.The study was approved by the Institutional Ethics Committee of AIIMS,Rishikesh.We used descriptive analysis and the Chi-squared test to analyze data.P value<0.05 was considered significant.RESULTS Out of 59 participants,only 11(18.6%)were certified for GCP.Most of the participants(64.4%)had“Average”knowledge,33.9%had“Good”knowledge and 1.7%had“Poor”knowledge.Only 49%of participants had satisfactory practices related to GCP.There was a significant difference in the knowledge based on the current academic position for the items assessing knowledge of institutional review board(P=0.010),confidentiality&privacy(P=0.011),and participant safety&adverse events(P<0.001).There was also a significant difference in knowledge of research misconduct(P=0.024)and participant safety&adverse events(P=0.011)based on certification of GCP.There was a notable difference in the practices related to recruitment&retention on the basis of current academic position(P<0.001)and certification of GCP(P=0.023).We also observed a considerable difference between the knowledge and practices of GCP among the participants(P=0.013).CONCLUSION Participants have basic knowledge of GCP but show a lack thereof in certain domains of GCP.This can be addressed by holding training sessions focusing on these particular domains.展开更多
Researchers from the Institute of Process Engineering(IPE)of the Chinese Academy of Sciences have proposed a new“nano-micro composite”concept for vaccine delivery.Based on this idea,they have developed a single-dose...Researchers from the Institute of Process Engineering(IPE)of the Chinese Academy of Sciences have proposed a new“nano-micro composite”concept for vaccine delivery.Based on this idea,they have developed a single-dose,dry-powder,inhalable vaccine platform using nano-micro composite multilevel structures,which has been successfully prepared in the laboratory.展开更多
Purpose:In studies of the research process,the association between how researchers conceptualize research and their strategic research agendas has been largely overlooked.This study aims to address this gap.Design/met...Purpose:In studies of the research process,the association between how researchers conceptualize research and their strategic research agendas has been largely overlooked.This study aims to address this gap.Design/methodology/approach:This study analyzes this relationship using a dataset of more than 8,500 researchers across all scientific fields and the globe.It studies the associations between the dimensions of two inventories:the Conceptions of Research Inventory(CoRI)and the Multi-Dimensional Research Agenda Inventory—Revised(MDRAI-R).Findings:The findings show a relatively strong association between researchers’conceptions of research and their research agendas.While all conceptions of research are positively related to scientific ambition,the findings are mixed regarding how the dimensions of the two inventories relate to one another,which is significant for those seeking to understand the knowledge production process better.Research limitations:The study relies on self-reported data,which always carries a risk of response bias.Practical implications:The findings provide a greater understanding of the inner workings of knowledge processes and indicate that the two inventories,whether used individually or in combination,may provide complementary analytical perspectives to research performance indicators.They may thus offer important insights for managers of research environments regarding how to assess the research culture,beliefs,and conceptualizations of individual researchers and research teams when designing strategies to promote specific institutional research focuses and strategies.Originality/value:To the best of the authors’knowledge,this is the first study to associate research agendas and conceptions of research.It is based on a large sample of researchers working worldwide and in all fields of knowledge,which ensures that the findings have a reasonable degree of generalizability to the global population of researchers.展开更多
The majority of academic researchers present the results of their scientific activity on the Web. This trace can be used to derive useful information of their past, present activity and forecast the future intentions....The majority of academic researchers present the results of their scientific activity on the Web. This trace can be used to derive useful information of their past, present activity and forecast the future intentions. Hence, social network of academic researchers can be of important value for scientific community. This information can be retrieved from various data source currently available on the Web. From each of them a separate net-work can be built. In this paper we present a method which can be used to combine multiple single-relational networks into a single network which will combine all relations, hence it will be multi-relational.展开更多
Purpose:The ranking lists of highly cited researchers receive much public attention.In common interpretations,highly cited researchers are perceived to have made extraordinary contributions to science.Thus,the metrics...Purpose:The ranking lists of highly cited researchers receive much public attention.In common interpretations,highly cited researchers are perceived to have made extraordinary contributions to science.Thus,the metrics of highly cited researchers are often linked to notions of breakthroughs,scientific excellence,and lone geniuses.Design/methodology/approach:In this study,we analyze a sample of individuals who appear on Clarivate Analytics’Highly Cited Researchers list.The main purpose is to juxtapose the characteristics of their research performance against the claim that the list captures a small fraction of the researcher population that contributes disproportionately to extending the frontier and gaining—on behalf of society—knowledge and innovations that make the world healthier,richer,sustainable,and more secure.Findings:The study reveals that the highly cited articles of the selected individuals generally have a very large number of authors.Thus,these papers seldom represent individual contributions but rather are the result of large collective research efforts conducted in research consortia.This challenges the common perception of highly cited researchers as individual geniuses who can be singled out for their extraordinary contributions.Moreover,the study indicates that a few of the individuals have not even contributed to highly cited original research but rather to reviews or clinical guidelines.Finally,the large number of authors of the papers implies that the ranking list is very sensitive to the specific method used for allocating papers and citations to individuals.In the"whole count"methodology applied by Clarivate Analytics,each author gets full credit of the papers regardless of the number of additional co-authors.The study shows that the ranking list would look very different using an alternative fractionalised methodology.Research limitations:The study is based on a limited part of the total population of highly cited researchers.Practical implications:It is concluded that"excellence"understood as highly cited encompasses very different types of research and researchers of which many do not fit with dominant preconceptions.Originality/value:The study develops further knowledge on highly cited researchers,addressing questions such as who becomes highly cited and the type of research that benefits by defining excellence in terms of citation scores and specific counting methods.展开更多
Context:Since the end of 2019,the COVID-19 pandemic had a worst impact on world’s economy,healthcare,and education.There are several aspects where the impact of COVID-19 could be visualized.Among these,one aspect is ...Context:Since the end of 2019,the COVID-19 pandemic had a worst impact on world’s economy,healthcare,and education.There are several aspects where the impact of COVID-19 could be visualized.Among these,one aspect is the productivity of researcher,which plays a significant role in the success of an organization.Problem:There are several factors that could be aligned with the researcher’s productivity of each domain and whose analysis through researcher’s feedback could be beneficial for decision makers in terms of their decision making and implementation of mitigation plans for the success of an organization.Method:We perform an empirical study to investigate the substantial impact of COVID-19 on the productivity of researchers by analyzing the relevant factors through their perceptions.Our study aims to find out the impact of COVID-19 on the researcher’s productivity that are working in different fields.In this study,we conduct a questionnaire-based analysis,which included feedback of 152 researchers of certain domains.These researchers are currently involved in different research activities.Subsequently,we perform a statistical analysis to analyze the collected responses and report the findings.Findings:The results indicate the substantial impact of COVID-19 pandemics on the researcher’s productivity in terms of mental disturbance,lack of regular meetings,and field visits for the collection of primary data.Conclusion:Finally,it is concluded that researcher’s daily or weekly meetings with their supervisors and colleagues are necessary to keep them more productive in task completion.These findings would help the decision makers of an organization in the settlement of their plan for the success of an organization.展开更多
This paper analyzes the current situation of training young scientific and technological talents,attracting talents and making good use of talents in Changli Fruit Tree Research Institute of Hebei Academy of Agricultu...This paper analyzes the current situation of training young scientific and technological talents,attracting talents and making good use of talents in Changli Fruit Tree Research Institute of Hebei Academy of Agricultural and Forestry Sciences.There are some problems,such as lack of talent recruitment planning,and lack of follow-up training mechanism.This paper puts forward some measures,such as formulating a scientific recruitment plan,making a follow-up plan for talent training,building an ability-and performance-oriented evaluation mechanism for scientific and technological talents,so as to attach importance to the training of young scientific research talents and promote the echelon construction of the research institute.展开更多
Most research-based fertilizer inputs proposed for small scale farmers to increase their productivity do not achieve the required results and should consider indigenous practices. This study evaluates the practices of...Most research-based fertilizer inputs proposed for small scale farmers to increase their productivity do not achieve the required results and should consider indigenous practices. This study evaluates the practices of nutrient fertilizer input by farmers and researchers and relates them to their corresponding yields and profit so as to establish the appropriateness of the practices in 13 districts of the Northern regions of Ghana. Soil nutrients assessment of Nitrogen (N), Phosphorus (P) and Potassium (K) contents used to evaluate the soil NPK status was based on previous studies. Data on fertilizer application by farmers and researchers were obtained from the Savanna Agricultural Research Institute (SARI). The amount of N, P and K fertilizer input in 13 Districts and its associated maize grain yields by both farmers (89) and researchers were calculated and compared using two-sample t-test. The t-test results indicated that average amount of fertilizer input by researchers was significantly (p < 0.05) higher than the average amount of fertilizer input by the smallholder farmers, but the high fertilizer input did not significantly (p = 0.74) increase researchers’ maize yields and profits in all 13 study districts grouped together, but there was maize increment in only eight districts. On the average, farmers from five districts applied low fertilizer and recorded low yields. However, when researchers increased quantities of fertilizer applied in these five districts, yield significantly (p < 0.05) increased. The outcome showed that smallholder farmers in these five districts could increase maize yields by 36% in the region should they adopt the maize production strategy by the researchers. The study concluded that, for best options, recommended fertilizer doses to enhance maize yields should consider district-specific farmers’ practices and soil NPK status. The study could enable better implementation of location-based nutrient recommendation in the Northern Region of Ghana.展开更多
A new study entitled"Hard-Sphere Random Close-Packed Au47Cd2(TBBT)31 Nanoclusters with a Faradaic Efficiency of up to 96%for Electrocatalytic CO2 Reduction to CO"recently appeared in the journal of Angewandt...A new study entitled"Hard-Sphere Random Close-Packed Au47Cd2(TBBT)31 Nanoclusters with a Faradaic Efficiency of up to 96%for Electrocatalytic CO2 Reduction to CO"recently appeared in the journal of Angewandte Chemie International Edition.展开更多
On January 3,2019,the Chang’e 4 probe sent back photos of the Von Karman crater in the South Pole-Aitken basin,after its successful soft landing, the first ever by a man-made vehicle, on the surface of the far side o...On January 3,2019,the Chang’e 4 probe sent back photos of the Von Karman crater in the South Pole-Aitken basin,after its successful soft landing, the first ever by a man-made vehicle, on the surface of the far side of the moon. This feat was hailed as opening a new chapter in mankind’s lunar exploration.展开更多
The Report of the 18thNational Congress of the CPC pointed out that we must earnestly promote public diplomacy.The key phrases here are"we"and"earnestly".Who are"we"?What kind of organiza...The Report of the 18thNational Congress of the CPC pointed out that we must earnestly promote public diplomacy.The key phrases here are"we"and"earnestly".Who are"we"?What kind of organizations and people does it refer to?How can be"earnest"?These questions are worth the contemplation of people like us who are performing China’s public diplomacy.展开更多
Scientists have found few cluesabout the origin of feathersfrom the structurally modemfeathers of Archaeopteryx, the ear-liest bird known to date. A new hy-pothesis was recently proposed
In recent years,flexible materials are widely concerned by scientists because of their unique bendingproperties and potential applications in flexible wearable electronic devices.Magnetic material,especially one dimen...In recent years,flexible materials are widely concerned by scientists because of their unique bendingproperties and potential applications in flexible wearable electronic devices.Magnetic material,especially one dimensional nano structure with high orientation,are also research focus for researchers due to their important applications in the fields of high density magnetic storage and sensors.Compared展开更多
In the past decades,a number of researchers have tried hard to identify the move-step structure of different sections in research articles(RAs)from various disciplines.However,there is a very few amount of previous st...In the past decades,a number of researchers have tried hard to identify the move-step structure of different sections in research articles(RAs)from various disciplines.However,there is a very few amount of previous studies conducted on the move-step structure of the Introduction section of English medical science research articles(MSRAs)written by Chinese researchers published in international journals.In order to fill this gap,the present study aims to identify the moves,steps,and their structure of the Introduction section of English MSRAs written by Chinese researchers at Zunyi Medical University(ZMU)published in international journals.To create the target corpus of the present study,30 Introductions were purposively selected from 25 international medical science journals,which were published from 2007 to 2015.It is worth noting that all the authors are restricted to Chinese researchers only and at least one author must come from ZMU.The framework of Kanoksilapatham’s(2005)was adopted for the move-step analysis in the present study.The results demonstrated that these Introduction sections were generally written with three moves following the selected framework.In addition,there were two new steps that occurred in the Introduction section of these English MSRAs.In conclusion,the findings of the present study might provide a guideline for the research who plan to write English MSRAs for international articles more effectively.Moreover,the findings may provide valuable information for academic writing textbook designers as well.展开更多
In order to support scientific evaluation and decision-making,this paper characterizes and identifies core researchers and their research topics by modeling the portrait of core researchers in technical fields.In this...In order to support scientific evaluation and decision-making,this paper characterizes and identifies core researchers and their research topics by modeling the portrait of core researchers in technical fields.In this paper,we constructed a portrait model of core researchers,explained the information attributes and their label data in each dimension of the portrait.Selected six identification indicators that can be measured,used the CRITIC method and gray correlation method to determine the weight coefficient and comprehensive score of the index,and designed quantitative identification methods for core researchers using Price's calculation formula and golden section coefficient.Took the field of artificial intelligence as an example for empirical analysis and result verification,selected representative core researchers to track the changes of research topics at the two levels of their teams and individuals,and characterize them based on the portrait model.展开更多
Diabetic eye disease refers to a group of eye complications that occur in diabetic patients and include diabetic retinopathy, diabetic macular edema, diabetic cataracts, and diabetic glaucoma. However, the global epid...Diabetic eye disease refers to a group of eye complications that occur in diabetic patients and include diabetic retinopathy, diabetic macular edema, diabetic cataracts, and diabetic glaucoma. However, the global epidemiology of these conditions has not been well characterized. In this study, we collected information on diabetic eye disease-related research grants from seven representative countries––the United States, China, Japan, the United Kingdom, Spain, Germany, and France––by searching for all global diabetic eye disease journal articles in the Web of Science and Pub Med databases, all global registered clinical trials in the Clinical Trials database, and new drugs approved by the United States, China, Japan, and EU agencies from 2012 to 2021. During this time period, diabetic retinopathy accounted for the vast majority(89.53%) of the 2288 government research grants that were funded to investigate diabetic eye disease, followed by diabetic macular edema(9.27%). The United States granted the most research funding for diabetic eye disease out of the seven countries assessed. The research objectives of grants focusing on diabetic retinopathy and diabetic macular edema differed by country. Additionally, the United States was dominant in terms of research output, publishing 17.53% of global papers about diabetic eye disease and receiving 22.58% of total citations. The United States and the United Kingdom led international collaborations in research into diabetic eye disease. Of the 415 clinical trials that we identified, diabetic macular edema was the major disease that was targeted for drug development(58.19%). Approximately half of the trials(49.13%) pertained to angiogenesis. However, few drugs were approved for ophthalmic(40 out of 1830;2.19%) and diabetic eye disease(3 out of 1830;0.02%) applications. Our findings show that basic and translational research related to diabetic eye disease in the past decade has not been highly active, and has yielded few new treatment methods and newly approved drugs.展开更多
Purpose:Interdisciplinary fields have become the driving force of modern science and a significant source of scientific innovation.However,there is still a paucity of analysis about the essential characteristics of di...Purpose:Interdisciplinary fields have become the driving force of modern science and a significant source of scientific innovation.However,there is still a paucity of analysis about the essential characteristics of disciplines’cross-disciplinary impact.Design/methodology/approach:In this study,we define cross-disciplinary impact on one discipline as its impact to other disciplines,and refer to a three-dimensional framework of variety-balance-disparity to characterize the structure of cross-disciplinary impact.The variety of cross-disciplinary impact of the discipline was defined as the proportion of the high cross-disciplinary impact publications,and the balance and disparity of cross-disciplinary impact were measured as well.To demonstrate the cross-disciplinary impact of the disciplines in science,we chose Microsoft Academic Graph(MAG)as the data source,and investigated the relationship between disciplines’cross-disciplinary impact and their positions in the Hierarchy of Science(HOS).Findings:Analytical results show that there is a significant correlation between the ranking of cross-disciplinary impact and the HOS structure,and that the discipline exerts a greater cross-disciplinary impact on its neighboring disciplines.Several bibliometric features that measure the hardness of a discipline,including the number of references,the number of cited disciplines,the citation distribution,and the Price index have a significant positive effect on the variety of cross-disciplinary impact.The number of references,the number of cited disciplines,and the citation distribution have significant positive and negative effects on balance and disparity,respectively.It is concluded that the less hard the discipline,the greater the cross-disciplinary impact,the higher balance and the lower disparity of cross-disciplinary impact.Research limitations:In the empirical analysis of HOS,we only included five broad disciplines.This study also has some biases caused by the data source and applied regression models.Practical implications:This study contributes to the formulation of discipline-specific policies and promotes the growth of interdisciplinary research,as well as offering fresh insights for predicting the cross-disciplinary impact of disciplines.Originality/value:This study provides a new perspective to properly understand the mechanisms of cross-disciplinary impact and disciplinary integration.展开更多
In recent years,humanized immune system(HIS)mice have been gradually used as models for preclinical research in pharmacotherapies and cell therapies with major breakthroughs in tumor and other fields,better mimicking ...In recent years,humanized immune system(HIS)mice have been gradually used as models for preclinical research in pharmacotherapies and cell therapies with major breakthroughs in tumor and other fields,better mimicking the human immune system and the tumor immune microenvironment,compared to traditional immunodeficient mice.To better promote the application of HIS mice in preclinical research,we se-lectively summarize the current prevalent and breakthrough research and evaluation of chimeric antigen receptor(CAR)-T cells in various antiviral and antitumor treat-ments.By exploring its application in preclinical research,we find that it can better reflect the actual clinical patient condition,with the advantages of providing high-efficiency detection indicators,even for progressive research and development.We believe that it has better clinical patient simulation and promotion for the updated design of CAR-T cell therapy than directly transplanted immunodeficient mice.The characteristics of the main models are proposed to improve the use defects of the existing models by reducing the limitation of antihost reaction,combining multiple models,and unifying sources and organoid substitution.Strategy study of relapse and toxicity after CAR-T treatment also provides more possibilities for application and development.展开更多
文摘Purpose:Diaspora researchers work in one country but have ancestral origins in another,either through moves during a research career(mobile diaspora researchers)or by starting research in the target country(embedded diaspora researchers).Whilst mobile researchers might be tracked through affiliation changes in bibliometric databases,embedded researchers cannot.This article reports an evidence-based discussion of which countries’diaspora researchers can be partially tracked using first or last names,addressing this limitation.Design/methodology/approach:A frequency analysis of first and last names of authors of all Scopus journal articles 2001-2021 for 200 countries or regions.Findings:There are great variations in the extent to which first or last names are uniquely national,from Monserrat(no unique first names)to Thailand(81%unique last names).Nevertheless,most countries have a subset of first or last names that are relatively unique.For the 50 countries with the most researchers,authors with relatively national names are always more likely to research their name-associated country,suggesting a continued national association.Lists of researchers’first and last name frequencies and proportions are provided for 200 countries/regions.Research limitations:Only one period is tracked(2001-2021)and no attempt was made to validate the ancestral origins of any researcher.Practical implications:Simple name heuristics can be used to identify the international spread of a sample of most countries’diaspora researchers,but some manual checks of individual names are needed to weed out false matches.This can supplement mobile researcher data from bibliometric databases.Originality/value:This is the first attempt to list name associations for the authors of all countries and large regions,and to identify the countries for which diaspora researchers could be tracked by name.
文摘Background:Researchers have a higher risk of anxiety and depression than the general population,so it is important to promote researchers’mental health.Method:Based on the data from 3210 global researchers surveyed by the journal Nature in 2021,confirmatory factor analysis,OLS regression and other regressions were used to explore the research incentive dimensions and their effects on researchers’mental health.Results:(1)Material incentive factors,work-family life balance factors,good organizational environment and spiritual motivation had significant positive effects on researchers’mental health.(2)The spiritual motivation could better promote researchers’mental health than the other factors.(3)Heterogeneity analysis showed that material incentive factors and spiritual motivation created more significant stimulating effects on the mental health of humanities and social sciences researchers.Work-family life balance factors were more effective in promoting the mental health of the mid-career group and the overtime group.Conclusion:Application of the four research incentives resulted in lower likelihood of anxiety or depression among researchers,and special attention should be paid to the role of the spiritual motivation.In order to promote researchers’mental health,different incentives should be applied to different researcher groups to better improve researchers’mental health.
文摘BACKGROUND Good clinical practice(GCP)is put in place to protect human participants in clinical trials as well as to ensure the quality of research.Non-adherence to these guidelines can produce research that may not meet the standards set by the scientific community.Therefore,it must be ensured that researchers are wellversed in the GCP.But not much is known about the knowledge and practices of the GCP in the medical colleges of North India.AIM To assess the knowledge and practices of researchers about GCP and analyze these with respect to the demographics of participants.METHODS This is a cross-sectional study.A self-structured questionnaire about GCP,after expert validations,was circulated among researchers,at a tertiary healthcare institute,All India Institute of Medical Sciences(AIIMS),Rishikesh.A total of 59 individuals,who were selected by universal sampling,participated in the study.All healthcare workers who have been investigators of Institutional Ethics Committee-approved research projects,except residents and faculty,and are still a part of the institute have been included in the study.The study was approved by the Institutional Ethics Committee of AIIMS,Rishikesh.We used descriptive analysis and the Chi-squared test to analyze data.P value<0.05 was considered significant.RESULTS Out of 59 participants,only 11(18.6%)were certified for GCP.Most of the participants(64.4%)had“Average”knowledge,33.9%had“Good”knowledge and 1.7%had“Poor”knowledge.Only 49%of participants had satisfactory practices related to GCP.There was a significant difference in the knowledge based on the current academic position for the items assessing knowledge of institutional review board(P=0.010),confidentiality&privacy(P=0.011),and participant safety&adverse events(P<0.001).There was also a significant difference in knowledge of research misconduct(P=0.024)and participant safety&adverse events(P=0.011)based on certification of GCP.There was a notable difference in the practices related to recruitment&retention on the basis of current academic position(P<0.001)and certification of GCP(P=0.023).We also observed a considerable difference between the knowledge and practices of GCP among the participants(P=0.013).CONCLUSION Participants have basic knowledge of GCP but show a lack thereof in certain domains of GCP.This can be addressed by holding training sessions focusing on these particular domains.
文摘Researchers from the Institute of Process Engineering(IPE)of the Chinese Academy of Sciences have proposed a new“nano-micro composite”concept for vaccine delivery.Based on this idea,they have developed a single-dose,dry-powder,inhalable vaccine platform using nano-micro composite multilevel structures,which has been successfully prepared in the laboratory.
基金supported by doctoral grant PD/BD/113999/2015 from the Fundacao para a Ciência e Tecnologia and by the European Social Fund and the Portuguese Ministry of Science and Educationfunded by the Research Grants Council (Hong Kong SAR, China)project entitled “Characterizing researchers’ research agenda-setting: an international perspective across fields of knowledge” (project number: 27608516)。
文摘Purpose:In studies of the research process,the association between how researchers conceptualize research and their strategic research agendas has been largely overlooked.This study aims to address this gap.Design/methodology/approach:This study analyzes this relationship using a dataset of more than 8,500 researchers across all scientific fields and the globe.It studies the associations between the dimensions of two inventories:the Conceptions of Research Inventory(CoRI)and the Multi-Dimensional Research Agenda Inventory—Revised(MDRAI-R).Findings:The findings show a relatively strong association between researchers’conceptions of research and their research agendas.While all conceptions of research are positively related to scientific ambition,the findings are mixed regarding how the dimensions of the two inventories relate to one another,which is significant for those seeking to understand the knowledge production process better.Research limitations:The study relies on self-reported data,which always carries a risk of response bias.Practical implications:The findings provide a greater understanding of the inner workings of knowledge processes and indicate that the two inventories,whether used individually or in combination,may provide complementary analytical perspectives to research performance indicators.They may thus offer important insights for managers of research environments regarding how to assess the research culture,beliefs,and conceptualizations of individual researchers and research teams when designing strategies to promote specific institutional research focuses and strategies.Originality/value:To the best of the authors’knowledge,this is the first study to associate research agendas and conceptions of research.It is based on a large sample of researchers working worldwide and in all fields of knowledge,which ensures that the findings have a reasonable degree of generalizability to the global population of researchers.
文摘The majority of academic researchers present the results of their scientific activity on the Web. This trace can be used to derive useful information of their past, present activity and forecast the future intentions. Hence, social network of academic researchers can be of important value for scientific community. This information can be retrieved from various data source currently available on the Web. From each of them a separate net-work can be built. In this paper we present a method which can be used to combine multiple single-relational networks into a single network which will combine all relations, hence it will be multi-relational.
基金the Research Council of Norway,grant number 256223(the R-QUEST centre)。
文摘Purpose:The ranking lists of highly cited researchers receive much public attention.In common interpretations,highly cited researchers are perceived to have made extraordinary contributions to science.Thus,the metrics of highly cited researchers are often linked to notions of breakthroughs,scientific excellence,and lone geniuses.Design/methodology/approach:In this study,we analyze a sample of individuals who appear on Clarivate Analytics’Highly Cited Researchers list.The main purpose is to juxtapose the characteristics of their research performance against the claim that the list captures a small fraction of the researcher population that contributes disproportionately to extending the frontier and gaining—on behalf of society—knowledge and innovations that make the world healthier,richer,sustainable,and more secure.Findings:The study reveals that the highly cited articles of the selected individuals generally have a very large number of authors.Thus,these papers seldom represent individual contributions but rather are the result of large collective research efforts conducted in research consortia.This challenges the common perception of highly cited researchers as individual geniuses who can be singled out for their extraordinary contributions.Moreover,the study indicates that a few of the individuals have not even contributed to highly cited original research but rather to reviews or clinical guidelines.Finally,the large number of authors of the papers implies that the ranking list is very sensitive to the specific method used for allocating papers and citations to individuals.In the"whole count"methodology applied by Clarivate Analytics,each author gets full credit of the papers regardless of the number of additional co-authors.The study shows that the ranking list would look very different using an alternative fractionalised methodology.Research limitations:The study is based on a limited part of the total population of highly cited researchers.Practical implications:It is concluded that"excellence"understood as highly cited encompasses very different types of research and researchers of which many do not fit with dominant preconceptions.Originality/value:The study develops further knowledge on highly cited researchers,addressing questions such as who becomes highly cited and the type of research that benefits by defining excellence in terms of citation scores and specific counting methods.
文摘Context:Since the end of 2019,the COVID-19 pandemic had a worst impact on world’s economy,healthcare,and education.There are several aspects where the impact of COVID-19 could be visualized.Among these,one aspect is the productivity of researcher,which plays a significant role in the success of an organization.Problem:There are several factors that could be aligned with the researcher’s productivity of each domain and whose analysis through researcher’s feedback could be beneficial for decision makers in terms of their decision making and implementation of mitigation plans for the success of an organization.Method:We perform an empirical study to investigate the substantial impact of COVID-19 on the productivity of researchers by analyzing the relevant factors through their perceptions.Our study aims to find out the impact of COVID-19 on the researcher’s productivity that are working in different fields.In this study,we conduct a questionnaire-based analysis,which included feedback of 152 researchers of certain domains.These researchers are currently involved in different research activities.Subsequently,we perform a statistical analysis to analyze the collected responses and report the findings.Findings:The results indicate the substantial impact of COVID-19 pandemics on the researcher’s productivity in terms of mental disturbance,lack of regular meetings,and field visits for the collection of primary data.Conclusion:Finally,it is concluded that researcher’s daily or weekly meetings with their supervisors and colleagues are necessary to keep them more productive in task completion.These findings would help the decision makers of an organization in the settlement of their plan for the success of an organization.
文摘This paper analyzes the current situation of training young scientific and technological talents,attracting talents and making good use of talents in Changli Fruit Tree Research Institute of Hebei Academy of Agricultural and Forestry Sciences.There are some problems,such as lack of talent recruitment planning,and lack of follow-up training mechanism.This paper puts forward some measures,such as formulating a scientific recruitment plan,making a follow-up plan for talent training,building an ability-and performance-oriented evaluation mechanism for scientific and technological talents,so as to attach importance to the training of young scientific research talents and promote the echelon construction of the research institute.
文摘Most research-based fertilizer inputs proposed for small scale farmers to increase their productivity do not achieve the required results and should consider indigenous practices. This study evaluates the practices of nutrient fertilizer input by farmers and researchers and relates them to their corresponding yields and profit so as to establish the appropriateness of the practices in 13 districts of the Northern regions of Ghana. Soil nutrients assessment of Nitrogen (N), Phosphorus (P) and Potassium (K) contents used to evaluate the soil NPK status was based on previous studies. Data on fertilizer application by farmers and researchers were obtained from the Savanna Agricultural Research Institute (SARI). The amount of N, P and K fertilizer input in 13 Districts and its associated maize grain yields by both farmers (89) and researchers were calculated and compared using two-sample t-test. The t-test results indicated that average amount of fertilizer input by researchers was significantly (p < 0.05) higher than the average amount of fertilizer input by the smallholder farmers, but the high fertilizer input did not significantly (p = 0.74) increase researchers’ maize yields and profits in all 13 study districts grouped together, but there was maize increment in only eight districts. On the average, farmers from five districts applied low fertilizer and recorded low yields. However, when researchers increased quantities of fertilizer applied in these five districts, yield significantly (p < 0.05) increased. The outcome showed that smallholder farmers in these five districts could increase maize yields by 36% in the region should they adopt the maize production strategy by the researchers. The study concluded that, for best options, recommended fertilizer doses to enhance maize yields should consider district-specific farmers’ practices and soil NPK status. The study could enable better implementation of location-based nutrient recommendation in the Northern Region of Ghana.
文摘A new study entitled"Hard-Sphere Random Close-Packed Au47Cd2(TBBT)31 Nanoclusters with a Faradaic Efficiency of up to 96%for Electrocatalytic CO2 Reduction to CO"recently appeared in the journal of Angewandte Chemie International Edition.
文摘On January 3,2019,the Chang’e 4 probe sent back photos of the Von Karman crater in the South Pole-Aitken basin,after its successful soft landing, the first ever by a man-made vehicle, on the surface of the far side of the moon. This feat was hailed as opening a new chapter in mankind’s lunar exploration.
文摘The Report of the 18thNational Congress of the CPC pointed out that we must earnestly promote public diplomacy.The key phrases here are"we"and"earnestly".Who are"we"?What kind of organizations and people does it refer to?How can be"earnest"?These questions are worth the contemplation of people like us who are performing China’s public diplomacy.
文摘Scientists have found few cluesabout the origin of feathersfrom the structurally modemfeathers of Archaeopteryx, the ear-liest bird known to date. A new hy-pothesis was recently proposed
文摘In recent years,flexible materials are widely concerned by scientists because of their unique bendingproperties and potential applications in flexible wearable electronic devices.Magnetic material,especially one dimensional nano structure with high orientation,are also research focus for researchers due to their important applications in the fields of high density magnetic storage and sensors.Compared
文摘In the past decades,a number of researchers have tried hard to identify the move-step structure of different sections in research articles(RAs)from various disciplines.However,there is a very few amount of previous studies conducted on the move-step structure of the Introduction section of English medical science research articles(MSRAs)written by Chinese researchers published in international journals.In order to fill this gap,the present study aims to identify the moves,steps,and their structure of the Introduction section of English MSRAs written by Chinese researchers at Zunyi Medical University(ZMU)published in international journals.To create the target corpus of the present study,30 Introductions were purposively selected from 25 international medical science journals,which were published from 2007 to 2015.It is worth noting that all the authors are restricted to Chinese researchers only and at least one author must come from ZMU.The framework of Kanoksilapatham’s(2005)was adopted for the move-step analysis in the present study.The results demonstrated that these Introduction sections were generally written with three moves following the selected framework.In addition,there were two new steps that occurred in the Introduction section of these English MSRAs.In conclusion,the findings of the present study might provide a guideline for the research who plan to write English MSRAs for international articles more effectively.Moreover,the findings may provide valuable information for academic writing textbook designers as well.
基金support from the National Social Science Fund of China(16ZDA224)。
文摘In order to support scientific evaluation and decision-making,this paper characterizes and identifies core researchers and their research topics by modeling the portrait of core researchers in technical fields.In this paper,we constructed a portrait model of core researchers,explained the information attributes and their label data in each dimension of the portrait.Selected six identification indicators that can be measured,used the CRITIC method and gray correlation method to determine the weight coefficient and comprehensive score of the index,and designed quantitative identification methods for core researchers using Price's calculation formula and golden section coefficient.Took the field of artificial intelligence as an example for empirical analysis and result verification,selected representative core researchers to track the changes of research topics at the two levels of their teams and individuals,and characterize them based on the portrait model.
基金supported by the National Natural Science Foundation of China,No.82122009 (to JX)Science Research Foundation ofAier Eye Hospital Group,No.AM2001D1 (to JX)the Natural Science Foundation of Hunan Province,No.2020JJ5002 (to SJ)。
文摘Diabetic eye disease refers to a group of eye complications that occur in diabetic patients and include diabetic retinopathy, diabetic macular edema, diabetic cataracts, and diabetic glaucoma. However, the global epidemiology of these conditions has not been well characterized. In this study, we collected information on diabetic eye disease-related research grants from seven representative countries––the United States, China, Japan, the United Kingdom, Spain, Germany, and France––by searching for all global diabetic eye disease journal articles in the Web of Science and Pub Med databases, all global registered clinical trials in the Clinical Trials database, and new drugs approved by the United States, China, Japan, and EU agencies from 2012 to 2021. During this time period, diabetic retinopathy accounted for the vast majority(89.53%) of the 2288 government research grants that were funded to investigate diabetic eye disease, followed by diabetic macular edema(9.27%). The United States granted the most research funding for diabetic eye disease out of the seven countries assessed. The research objectives of grants focusing on diabetic retinopathy and diabetic macular edema differed by country. Additionally, the United States was dominant in terms of research output, publishing 17.53% of global papers about diabetic eye disease and receiving 22.58% of total citations. The United States and the United Kingdom led international collaborations in research into diabetic eye disease. Of the 415 clinical trials that we identified, diabetic macular edema was the major disease that was targeted for drug development(58.19%). Approximately half of the trials(49.13%) pertained to angiogenesis. However, few drugs were approved for ophthalmic(40 out of 1830;2.19%) and diabetic eye disease(3 out of 1830;0.02%) applications. Our findings show that basic and translational research related to diabetic eye disease in the past decade has not been highly active, and has yielded few new treatment methods and newly approved drugs.
基金funded by the National Natural Science Foundation of China(NSFC)Grant Nos.71921002 and 72174154.
文摘Purpose:Interdisciplinary fields have become the driving force of modern science and a significant source of scientific innovation.However,there is still a paucity of analysis about the essential characteristics of disciplines’cross-disciplinary impact.Design/methodology/approach:In this study,we define cross-disciplinary impact on one discipline as its impact to other disciplines,and refer to a three-dimensional framework of variety-balance-disparity to characterize the structure of cross-disciplinary impact.The variety of cross-disciplinary impact of the discipline was defined as the proportion of the high cross-disciplinary impact publications,and the balance and disparity of cross-disciplinary impact were measured as well.To demonstrate the cross-disciplinary impact of the disciplines in science,we chose Microsoft Academic Graph(MAG)as the data source,and investigated the relationship between disciplines’cross-disciplinary impact and their positions in the Hierarchy of Science(HOS).Findings:Analytical results show that there is a significant correlation between the ranking of cross-disciplinary impact and the HOS structure,and that the discipline exerts a greater cross-disciplinary impact on its neighboring disciplines.Several bibliometric features that measure the hardness of a discipline,including the number of references,the number of cited disciplines,the citation distribution,and the Price index have a significant positive effect on the variety of cross-disciplinary impact.The number of references,the number of cited disciplines,and the citation distribution have significant positive and negative effects on balance and disparity,respectively.It is concluded that the less hard the discipline,the greater the cross-disciplinary impact,the higher balance and the lower disparity of cross-disciplinary impact.Research limitations:In the empirical analysis of HOS,we only included five broad disciplines.This study also has some biases caused by the data source and applied regression models.Practical implications:This study contributes to the formulation of discipline-specific policies and promotes the growth of interdisciplinary research,as well as offering fresh insights for predicting the cross-disciplinary impact of disciplines.Originality/value:This study provides a new perspective to properly understand the mechanisms of cross-disciplinary impact and disciplinary integration.
基金CAMS Innovation Fund for Medical Sciences,Grant/Award Number:2021-I2M-1-035National Key Research and Development Project,Grant/Award Number:2022YFA1103803。
文摘In recent years,humanized immune system(HIS)mice have been gradually used as models for preclinical research in pharmacotherapies and cell therapies with major breakthroughs in tumor and other fields,better mimicking the human immune system and the tumor immune microenvironment,compared to traditional immunodeficient mice.To better promote the application of HIS mice in preclinical research,we se-lectively summarize the current prevalent and breakthrough research and evaluation of chimeric antigen receptor(CAR)-T cells in various antiviral and antitumor treat-ments.By exploring its application in preclinical research,we find that it can better reflect the actual clinical patient condition,with the advantages of providing high-efficiency detection indicators,even for progressive research and development.We believe that it has better clinical patient simulation and promotion for the updated design of CAR-T cell therapy than directly transplanted immunodeficient mice.The characteristics of the main models are proposed to improve the use defects of the existing models by reducing the limitation of antihost reaction,combining multiple models,and unifying sources and organoid substitution.Strategy study of relapse and toxicity after CAR-T treatment also provides more possibilities for application and development.
