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Electromagnetic Performance Analysis of Variable Flux Memory Machines with Series-magnetic-circuit and Different Rotor Topologies
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作者 Qiang Wei Z.Q.Zhu +4 位作者 Yan Jia Jianghua Feng Shuying Guo Yifeng Li Shouzhi Feng 《CES Transactions on Electrical Machines and Systems》 EI CSCD 2024年第1期3-11,共9页
In this paper,the electromagnetic performance of variable flux memory(VFM)machines with series-magnetic-circuit is investigated and compared for different rotor topologies.Based on a V-type VFM machine,five topologies... In this paper,the electromagnetic performance of variable flux memory(VFM)machines with series-magnetic-circuit is investigated and compared for different rotor topologies.Based on a V-type VFM machine,five topologies with different interior permanent magnet(IPM)arrangements are evolved and optimized under same constrains.Based on two-dimensional(2-D)finite element(FE)method,their electromagnetic performance at magnetization and demagnetization states is evaluated.It reveals that the iron bridge and rotor lamination region between constant PM(CPM)and variable PM(VPM)play an important role in torque density and flux regulation(FR)capabilities.Besides,the global efficiency can be improved in VFM machines by adjusting magnetization state(MS)under different operating conditions. 展开更多
关键词 Memory machine Permanent magnet rotor topologies Series magnetic circuit Variable flux
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Optimization of the Gas Generator in Composite Power System with Tip-Jet Rotor
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作者 Jianxiang Tang Yifei Wu +1 位作者 Yun Wang Jinwu Wu 《Journal of Power and Energy Engineering》 2024年第3期60-74,共15页
The key and bottleneck of research on the tip-jet rotor compound helicopter lies in the power system. Computational Fluid Dynamics (CFD) was used to numerically simulate the gas generator and rotor inner passage of th... The key and bottleneck of research on the tip-jet rotor compound helicopter lies in the power system. Computational Fluid Dynamics (CFD) was used to numerically simulate the gas generator and rotor inner passage of the tip-jet rotor composite power system, studying the effects of intake mode, inner cavity structure, propellant components, and injection amount on the characteristics of the composite power system. The results show that when a single high-temperature exhaust gas enters, the gas generator outlet fluid is uneven and asymmetric;when two-way high-temperature exhaust gas enters, the outlet temperature of the gas generator with a tilted inlet is more uniform than that with a vertical inlet;adding an inner cavity improves the temperature and velocity distribution of the gas generator's internal flow field;increasing the energy of the propellant is beneficial for improving the available moment. 展开更多
关键词 Tip-Jet Driven rotor Composite Power System Gas Generator Optimization Hydrogen Peroxide Aerodynamic Characteristics Numerical Simulation
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Analysis and Research on Aerodynamic Characteristics of Quad Tilt Rotor Aircraft
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作者 Jike Jia Xiaomei Ye +2 位作者 Guoyi He Qingjin Huang Zhile Hong 《Advances in Aerospace Science and Technology》 2024年第1期28-39,共12页
For the quad tilt rotor aircraft, a computational fluid dynamics method based on multiple reference frames (MRF) was used to analyze the influence of aerodynamic layout parameters on the aerodynamic characteristics of... For the quad tilt rotor aircraft, a computational fluid dynamics method based on multiple reference frames (MRF) was used to analyze the influence of aerodynamic layout parameters on the aerodynamic characteristics of the quad tilt rotor aircraft. Firstly, a numerical simulation method for the interference flow field of the quad tilt rotor aircraft is established. Based on this method, the aerodynamic characteristics of isolated rotors, rotor combinations at different lateral positions on the wing, and rotor rotation directions under different inflow velocities were calculated and analyzed, in order to grasp their aerodynamic interference laws and provide reference for the design and control theory research of such aircraft. 展开更多
关键词 Quad Tilt rotor Aircraft Analysis of Aerodynamic Characteristics CFD Method
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Dynamic stiffness characteristics of aero-engine elastic support structure and its effects on rotor systems:mechanism and numerical and experimental studies 被引量:2
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作者 Lei LI Zhong LUO +1 位作者 Kaining LIU Jilai ZHOU 《Applied Mathematics and Mechanics(English Edition)》 SCIE EI CSCD 2023年第2期221-236,共16页
The support structure of a rotor system is subject to vibration excitation,which results in the stiffness of the support structure varying with the excitation frequency(i.e.,the dynamic stiffness).However,the dynamic ... The support structure of a rotor system is subject to vibration excitation,which results in the stiffness of the support structure varying with the excitation frequency(i.e.,the dynamic stiffness).However,the dynamic stiffness and its effect mechanism have been rarely incorporated in open studies of the rotor system.Therefore,this study theoretically reveals the effect mechanism of dynamic stiffness on the rotor system.Then,the numerical study and experimental verification are conducted on the dynamic stiffness characteristics of a squirrel cage,which is a common support structure for aero-engine.Moreover,the static stiffness experiment is also performed for comparison.Finally,a rotor system model considering the dynamic stiffness of the support structure is presented.The presented rotor model is used to validate the results of the theoretical analysis.The results illustrate that the dynamic stiffness reduces the critical speed of the rotor system and may lead to a new resonance. 展开更多
关键词 dynamic stiffness squirrel cage rotor system dynamic characteristic critical speed
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Investigation of Nonlinear PI Multi-loop Control Strategy for Aircraft HVDC Generator System with Wound Rotor Synchronous Machine 被引量:1
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作者 Zhaoyang Qu Zhuoran Zhang +1 位作者 Jincai Li Heng Shi 《CES Transactions on Electrical Machines and Systems》 CSCD 2023年第1期92-99,共8页
In order to enhance the transient performance of aircraft high voltage DC(HVDC)generation system with wound rotor synchronous machine(WRSM)under a wide speed range,the nonlinear PI multi-loop control strategy is propo... In order to enhance the transient performance of aircraft high voltage DC(HVDC)generation system with wound rotor synchronous machine(WRSM)under a wide speed range,the nonlinear PI multi-loop control strategy is proposed in this paper.Traditional voltage control method is hard to achieve the dynamic performance requirements of the HVDC generation system under a wide speed range,so the nonlinear PI parameter adjustment,load current feedback and speed feedback are added to the voltage and excitation current double loop control.The transfer function of the HVDC generation system is derived,and the relationship between speed,load current and PI parameters is obtained.The PI parameters corresponding to the load at certain speed are used to shorten the adjusting time when the load suddenly changes.The dynamic responses in transient processes are analyzed by experiment.The results illustrate that the WRSM HVDC generator system with this method has better dynamic performance. 展开更多
关键词 Aircraft HVDC generation system More electric aircraft Transient performance Wound rotor synchronous machine
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Rotor performance enhancement by alternating current dielectric barrier discharge plasma actuation
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作者 赵光银 王畅 +2 位作者 杨永东 李国强 史喆羽 《Plasma Science and Technology》 SCIE EI CAS CSCD 2023年第1期120-127,共8页
An experimental system was established to explore the plasma flow control effect for helicopter rotors in hover mode.With the plasma actuator applied at the leading edge of the rotor blades,alternating current dielect... An experimental system was established to explore the plasma flow control effect for helicopter rotors in hover mode.With the plasma actuator applied at the leading edge of the rotor blades,alternating current dielectric barrier discharge(AC-DBD) plasma actuation was generated by a sinusoidal AC high-voltage generator.By direct force measurement,the influence of actuation parameters on the aerodynamic performance of the rotor was investigated at a tip Reynolds number of 1.7 × 105.AC-DBD actuation can delay the blade stall to more than 3° with a 20%increase of about in the thrust coefficient at the post-stall pitch.At a constant motor power driving the rotor,AC-DBD actuation could reduce the rotor’s torque at the stalled pitch and increase the rotational speed of the rotor.Also,AC-DBD actuation could maintain a relatively high hover efficiency of the rotor at large collective pitches.In a wide range of actuation parameters,AC-DBD plasma actuation could improve the rotor’s aerodynamic performance at large blade pitches.High-speed photography of the tuft motion on the blade’s upper surface showed that AC-DBD plasma actuation could promote the reattachment of the blade’s separation flow. 展开更多
关键词 rotor flow control plasma actuator dielectric barrier discharge force measurement
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Accelerator-mode islands and superdiffusion in double-kicked rotor
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作者 王风涤 方萍 《Chinese Physics B》 SCIE EI CAS CSCD 2023年第6期1-8,共8页
This paper presents a theoretical investigation of the presence of acceleration islands in the phase space of doublekicked rotor(DKR) systems, which can lead to superdiffusive behavior. We establish the conditions for... This paper presents a theoretical investigation of the presence of acceleration islands in the phase space of doublekicked rotor(DKR) systems, which can lead to superdiffusive behavior. We establish the conditions for the existence of period-1 acceleration centers and subsequently calculate the stability conditions for both period-1 and period-2 accelerate mode islands. A detailed analysis of local and global diffusion in the vicinity of the islands and the stickiness regions is provided. It is demonstrated that the mean stickiness time decays exponentially when the phase point is located in the interior of the island. Moreover, the phase point undergoes a power-law decay with a power equal to approximately 5when entering the sticky region. These findings offer a foundation for future exploration of quantum dynamics in the DKR system. 展开更多
关键词 superdiffuision accelerator-mode islands double-kicked rotor
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Crack Fault Diagnosis and Location Method for a Dual-Disk Hollow Shaft Rotor System Based on the Radial Basis Function Network and Pattern Recognition Neural Network
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作者 Yuhong Jin Lei Hou +1 位作者 Zhenyong Lu Yushu Chen 《Chinese Journal of Mechanical Engineering》 SCIE EI CAS CSCD 2023年第2期180-197,共18页
The crack fault is one of the most common faults in the rotor system,and researchers have paid close attention to its fault diagnosis.However,most studies focus on discussing the dynamic response characteristics cause... The crack fault is one of the most common faults in the rotor system,and researchers have paid close attention to its fault diagnosis.However,most studies focus on discussing the dynamic response characteristics caused by the crack rather than estimating the crack depth and position based on the obtained vibration signals.In this paper,a novel crack fault diagnosis and location method for a dual-disk hollow shaft rotor system based on the Radial basis function(RBF)network and Pattern recognition neural network(PRNN)is presented.Firstly,a rotor system model with a breathing crack suitable for a short-thick hollow shaft rotor is established based on the finite element method,where the crack's periodic opening and closing pattern and different degrees of crack depth are considered.Then,the dynamic response is obtained by the harmonic balance method.By adjusting the crack parameters,the dynamic characteristics related to the crack depth and position are analyzed through the amplitude-frequency responses and waterfall plots.The analysis results show that the first critical speed,first subcritical speed,first critical speed amplitude,and super-harmonic resonance peak at the first subcritical speed can be utilized for the crack fault diagnosis.Based on this,the RBF network and PRNN are adopted to determine the depth and approximate location of the crack respectively by taking the above dynamic characteristics as input.Test results show that the proposed method has high fault diagnosis accuracy.This research proposes a crack detection method adequate for the hollow shaft rotor system,where the crack depth and position are both unknown. 展开更多
关键词 Hollow shaft rotor Breathing crack Radial basis function network Pattern recognition neural network Machine learning
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Weak Fault Detection of Rotor Winding Inter-Turn Short Circuit in Excitation System Based on Residual Interval Observer
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作者 Gang Liu Xinqi Chen +4 位作者 Lijuan Bao Linbo Xu Chaochao Dai Lei Yang Chengmin Wang 《Structural Durability & Health Monitoring》 EI 2023年第4期337-351,共15页
Aiming at the fact that the rotor winding inter-turn weak faults can hardly be detected due to the strong electromagnetic coupling effect in the excitation system,an interval observer based on current residual is desi... Aiming at the fact that the rotor winding inter-turn weak faults can hardly be detected due to the strong electromagnetic coupling effect in the excitation system,an interval observer based on current residual is designed.Firstly,the mechanism of the inter-turn short circuit of the rotor winding in the excitation system is modeled under the premise of stable working conditions,and electromagnetic decoupling and system simplification are carried out through Park Transform.An interval observer is designed based on the current residual in the two-phase coordinate system,and the sensitive and stable conditions of the observer is preset.The fault diagnosis process based on the interval observer is formulated,and the observer gain matrix is convexly optimized by linear matrix inequality.The numerical simulation and experimental results show that the inter-turn short circuit weak fault is hardly detected directly through the current signal,but the fault is quickly and accurately diagnosed through the residual internal observer.Compared with the traditional fault diagnosis method based on excitation current,the diagnosis speed and accuracy are greatly improved,and the probability of misdiagnosis also decreases.This method provides a theoretical basis for weak fault identification of excitation systems,and is of great significance for the operation and maintenance of excitation systems. 展开更多
关键词 Excitation system interval observer rotor winding weak fault detection inter-turn shortcut
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Numerical Study on Low-Reynolds Compressible Flows around Mars Helicopter Rotor Blade Airfoil
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作者 Takuma Yamaguchi Masayuki Anyoji 《Journal of Flow Control, Measurement & Visualization》 CAS 2023年第2期30-48,共19页
High-speed rotor rotation under the low-density condition creates a special low-Reynolds compressible flow around the rotor blade airfoil where the compressibility effect on the laminar separated shear layer occurs. H... High-speed rotor rotation under the low-density condition creates a special low-Reynolds compressible flow around the rotor blade airfoil where the compressibility effect on the laminar separated shear layer occurs. However, the compressibility effect and shock wave generation associated with the increase in the Mach number (M) and the trend change due to their interference have not been clarified. The purpose is to clear the compressibility effect and its impact of shock wave generation on the flow field and aerodynamics. Therefore, we perform a two-dimensional unsteady calculation by Computational fluid dynamics (CFD) analysis using the CLF5605 airfoil used in the Mars helicopter Ingenuity, which succeeded in its first flight on Mars. The calculation conditions are set to the Reynolds number (Re) at 75% rotor span in hovering (Re = 15,400), and the Mach number was varied from incompressible (M = 0.2) to transonic (M = 1.2). The compressible fluid dynamics solver FaSTAR developed by the Japan aerospace exploration agency (JAXA) is used, and calculations are performed under multiple conditions in which the Mach number and angle of attack (α) are swept. The results show that a flow field is similar to that in the Earth’s atmosphere above M = 1.0, such as bow shock at the leading edge, whereas multiple λ-type shock waves are observed over the separated shear layer above α = 3° at M = 0.80. However, no significant difference is found in the C<sub>p</sub> distribution around the airfoil between M = 0.6 and M = 0.8. From the results, it is found that multiple λ-type shock waves have no significant effect on the airfoil surface pressure distribution, the separated shear layer effect is dominant in the surface pressure change and aerodynamic characteristics. 展开更多
关键词 CFD CLF5605 rotor Blade Airfoil Compressibility Effect Low-Reynolds Number Mars Helicopter Separation Bubble Shock Wave
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Coordinated Rotor-Side Control Strategy for Doubly-FedWind Turbine under Symmetrical and Asymmetrical Grid Faults
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作者 Quanchun Yan Chao Yuan +2 位作者 WenGu Yanan Liu Yiming Tang 《Energy Engineering》 EI 2023年第1期49-68,共20页
In order to solve the problems of rotor overvoltage,overcurrent and DC side voltage rise caused by grid voltage drops,a coordinated control strategy based on symmetrical and asymmetrical low voltage ride through of ro... In order to solve the problems of rotor overvoltage,overcurrent and DC side voltage rise caused by grid voltage drops,a coordinated control strategy based on symmetrical and asymmetrical low voltage ride through of rotor side converter of the doubly-fed generator is proposed.When the power grid voltage drops symmetrically,the generator approximate equation under steady-state conditions is no longer applicable.Considering the dynamic process of stator current excitation,according to the change of stator flux and the depth of voltage drop,the system can dynamically provide reactive power support for parallel nodes and suppress the rise of DC side voltage and rotor over-current.When the grid voltage drops asymmetrically,the positive and negative sequence components are separated in the rotating coordinate system.The doubly fed generator model is established to suppress the rotor positive sequence current and negative sequence current respectively.At the same time,the output voltage limit of the converter is discussed,and the reference value is adjusted within the allowable output voltage range.In order to adapt to the occurrence of different types of power grid faults and complex operating conditions,a fast switching module of fault type detection and rotor control mode is designed to detect the type of power grid faults and voltage drop depth in real time and switch the rotor side control mode dynamically.Finally,the simulation model of the doubly fed wind turbine is constructed in Matlab/Simulink.The simulation results verify that the proposed control strategy can improve the low-voltage ride through performance of the system when dealing with the symmetrical and asymmetric voltage drop of the power grid and identify the power grid fault type and provide the correct control strategy. 展开更多
关键词 Doubly-fed wind turbines symmetrical faults asymmetrical faults low voltage ride through rotor side control fault type detection
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The Advantages of Using Rotating Machines with Profiled Rotors
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作者 Gabriel Fischer-Szava Nicolae Băran +4 位作者 Mihaela Constantin Mugurel Oprea Cătălina Dobre Georgiana Duiculete Beatrice Ibrean 《World Journal of Engineering and Technology》 2023年第1期41-47,共7页
In order to achieve a lower consumed energy, the performance of a new type of rotating volumetric pump with two profiled rotors (variant I) which is compared with a centrifugal pump (variant II) is presented. The... In order to achieve a lower consumed energy, the performance of a new type of rotating volumetric pump with two profiled rotors (variant I) which is compared with a centrifugal pump (variant II) is presented. The analysis regarding the same flow rate of transported liquid and the same pressure increases points out the conduct of the system at the variation of the key operating parameters. The actual driving power of the rotating volumetric pump is higher stating that is more advantageous in operation. The effective efficiency of the system is improved due to the original constructive solution. 展开更多
关键词 Rotating Machine Volumetric Pump Profiled rotors Centrifugal Pump Energy Performances
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Permanent Magnet Assisted Synchronous Reluctance Motor with Asymmetric Rotor for High Torque Performance
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作者 Chengwu Diao Wenliang Zhao +1 位作者 Yan Liu Xiuhe Wang 《CES Transactions on Electrical Machines and Systems》 CSCD 2023年第2期179-186,共8页
Permanent magnet assisted synchronous reluctance motor(PMA-SynRM)is a kind of high torque density energy conversion device widely used in modern industry.In this paper,based on the basic topology of PMA-SynRM,a novel ... Permanent magnet assisted synchronous reluctance motor(PMA-SynRM)is a kind of high torque density energy conversion device widely used in modern industry.In this paper,based on the basic topology of PMA-SynRM,a novel PMA-SynRM of asymmetric rotor with position-biased magnet is proposed.The asymmetric rotor design with position-biased magnet realizes the concentration of magnetic field lines in the motor air gap to obtain higher electromagnetic torque,and makes both of magnetic and reluctance torque obtain the peak value at the same current phase angle.The asymmetric rotor configuration is theoretically illustrated by space vector diagram,and the feasibility of high torque performance of the motor is verified.Through the finite element simulation,the effect of the side barrier on output torque and the Mises stress under the rotor asymmetrical design are analyzed.Then the motor characteristics including airgap flux density,back EMF,magnetic torque,reluctance torque,torque ripple,losses,and efficiency are calculated for both the basic and proposed PMA-SynRMs.The results show that the proposed PMA-SynRM has higher torque and efficiency than the basic topology.Moreover,the torque ripple of the proposed PMA-SynRM is reduced by the method with harmonic current injection,and the torque characteristics in the whole current cycle are analyzed.Finally,the endurance to avoid PM demagnetization is confirmed based on the PM remanence calculation. 展开更多
关键词 Permanent magnet assisted synchronous reluctance motor Asymmetric rotor Magnetic torque Reluctance torque Torque ripple
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Hybrid URANS/LES Method of Flow Fields in Axial-flow Compressor Rotor Rotor
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作者 Jia-hao Xiao Ya-ping Ju Chu-hua Zhang 《风机技术》 2023年第6期17-23,85,共8页
Accurate and efficient prediction of the aerodynamic performance and flow details of axial-flow com-pressors is of great engineering application value for the aerodynamic design and flow control of axial-flow compres-... Accurate and efficient prediction of the aerodynamic performance and flow details of axial-flow com-pressors is of great engineering application value for the aerodynamic design and flow control of axial-flow compres-sors.In this work,a delayed detached eddy simulation method is developed and applied to numerically simulate the tur-bulent channel flow and the aerodynamic performance of NASA Rotor 35.Several acceleration techniques including parallel implementation are also used to speed up the iteration convergence.The mean velocity distribution and Reyn-olds stress distribution in the boundary layer of turbulent channel flow and the aerodynamic performance curve of NASA Rotor 35 are predicted.The good agreement between the present delayed detached eddy simulation results and the available direct numerical simulation results or experimental data confirms the effectiveness of the developed meth-od in the accurate and efficient prediction of complex flow in turbomachinery. 展开更多
关键词 Delayed Detached Eddy Simulation Turbulent Channel Flow Axial-flow Compressor rotor Parallel Implementation
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Effect of Spinning Parameters on Thick, Thin Places and Neps of Rotor Spun Yarn
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作者 Md. Reazuddin Repon Rajib Al Mamun +2 位作者 Selim Reza Mithun Kumer Das Tarikul Islam 《Journal of Textile Science and Technology》 2016年第3期47-55,共9页
Defect free yarn is a great demand for spinner, knitter, and weaver and also other textile personnel because numerous end products from knit apparels to woven fabrics, from towels to sheets and from carpets to industr... Defect free yarn is a great demand for spinner, knitter, and weaver and also other textile personnel because numerous end products from knit apparels to woven fabrics, from towels to sheets and from carpets to industrial fabrics characteristics significantly depend on the physical properties of yarn. The qualities of rotor yarn are really directed by spinning parameters. The aim of this study is to observe the effect of spinning parameters such as rotor diameter and speed on thick, thin places and neps of yarn in rotor spinning process. 0.11 sliver hank of 100% cotton was used to produce 12 Ne yarn. 65% virgin cotton and 35% wastage cotton were mixed together. The positive impact of spinning parameters on yarn properties were accessed by thick places, thin places and neps. Results indicate that the yarn qualities were improved with increasing of rotor speed and rotor diameter. The rotor diameter was settled to 43 mm while rotor speed fluctuated from 35,000 to 45,000 rpm and rotor speed was fixed to 35,000 rpm while rotor diameter across contrasts from 43 mm to 66 mm. 展开更多
关键词 rotor Spinning rotor Diameter rotor Speed Thick Places Thin Places NEPS
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基于SAMCEF Rotor的高速泵转子临界转速分析 被引量:2
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作者 段小辉 孔繁余 +2 位作者 冯子政 黄丹 宋艳文 《中国农村水利水电》 北大核心 2016年第3期129-134,共6页
为了提高高速泵的可靠性,利用专业的转子动力学特性分析软件SAMCEF Rotor对高速矿用抢险泵转子系统进行分析,研究转子的动力特性--临界转速及其振型,根据径向轴承参数建模,分别采用一维梁模型,二维傅里叶模型和三维实体模型进行计算比对... 为了提高高速泵的可靠性,利用专业的转子动力学特性分析软件SAMCEF Rotor对高速矿用抢险泵转子系统进行分析,研究转子的动力特性--临界转速及其振型,根据径向轴承参数建模,分别采用一维梁模型,二维傅里叶模型和三维实体模型进行计算比对,得到了各自的坎贝尔图和临界转速及振型。研究表明,三种模型吻合的状态基本一致,设计方案避免了工作转速达到临界转速产生共振现象。根据转子动力学分析软件SAMCEF Rotor分析研究,临界转速的计算方法比较完善,分析结果较为精确,且一维及二维模型求解法对计算机配置要求低,求解耗时短。 展开更多
关键词 SAMCEF rotor 转子系统 临界转速 振型 高速泵
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Rotor综合征1例 被引量:4
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作者 汤善宏 曾维政 +4 位作者 曾建梅 陈易华 吴晓玲 王钊 蒋明德 《肝脏》 2016年第3期231-232,共2页
患者,女,39岁,因"反复皮肤巩膜黄染37年,复发1周"入院。患者于37年前(2岁时)无明显诱因出现皮肤巩膜黄染,无腹胀、腹痛、恶心、呕吐,无心慌、气急、纳差、乏力,无寒战、高热等不适。检查发现黄疸指数高(具体数值不详),院外保肝治... 患者,女,39岁,因"反复皮肤巩膜黄染37年,复发1周"入院。患者于37年前(2岁时)无明显诱因出现皮肤巩膜黄染,无腹胀、腹痛、恶心、呕吐,无心慌、气急、纳差、乏力,无寒战、高热等不适。检查发现黄疸指数高(具体数值不详),院外保肝治疗效果不佳,反复求治,先后就诊于多家医院均未明确病因,黄疸持续存在。 展开更多
关键词 皮肤巩膜黄染 黄疸指数 rotor综合征1 直接胆红素 保肝治疗 结合胆红素 Gilbert 肝细胞 肝小叶结构 茵陈蒿汤加味
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一例Rotor综合征SLCO1B1和SLCO1B3基因突变分析 被引量:2
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作者 张志华 郑必霞 +2 位作者 李玫 金玉 林谦 《肝脏》 2016年第7期542-544,605,共4页
目的初步探讨1例Rotor综合征患者的临床特点和SLCO1B1和SLCO1B3基因突变情况,从分子遗传学角度分析该疾病的发生机制。方法收集患者临床资料,从外周血白细胞提取基因组DNA,采用二代测序进行四千种已知单基因遗传性疾病筛查,用Sanger测... 目的初步探讨1例Rotor综合征患者的临床特点和SLCO1B1和SLCO1B3基因突变情况,从分子遗传学角度分析该疾病的发生机制。方法收集患者临床资料,从外周血白细胞提取基因组DNA,采用二代测序进行四千种已知单基因遗传性疾病筛查,用Sanger测序法分析验证二代测序发现的突变位点。结果患儿主要临床表现为反复皮肤及巩膜黄染,实验室检查示高胆红素血症,直接、间接胆红素双向增高。高通量测序发现患儿携带SLCO1B1基因c.1738 C>T纯合突变和SLCO1B3基因c.360_481 del纯合突变。c.1738 C>T突变为无义突变,已有文献报道,推测导致蛋白的第580位氨基酸密码子由精氨酸变为终止密码子。c.360_481 del突变为移码突变,蛋白编码区的第360至481位碱基缺失。该变异未见文献报道,也未见SNP数据库收录。此变异使蛋白缺失40个氨基酸的同时还造成开放阅读框移码,可能造成蛋白功能丧失。结论 SLCO1B1和SLCO1B3基因突变导致的有机阴离子转运多肽OATP1B1和OATP1B3功能缺陷是该Rotor综合征患者临床表现的分子遗传基础。 展开更多
关键词 rotor综合征 SLCO1B1基因 SLCO1B3基因
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DYNAMIC BEHAVIOR OF A CRACKED FLEXIBLE ROTOR SUPPORTED ON JOURNAL BEARINGS 被引量:6
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作者 Zheng Jibing Meng Guang(Institute of Vibratian Engineering, Northwestern PolytechnicalUniversity, Xi’an, China, 710072) 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 1997年第1期28-35,共8页
The dynamic behavior of a cracked flexible rotor supported on three kinds ofjournal bearings is presented. Numerical experiments show that nonsynchronous responseswill happen due to the rotor crack, and the amplitudes... The dynamic behavior of a cracked flexible rotor supported on three kinds ofjournal bearings is presented. Numerical experiments show that nonsynchronous responseswill happen due to the rotor crack, and the amplitudes of the nonsynchronous componentsbecome larger with the increase of crack. On the other hand, the fluid forces of journalbearings can suppress the nonsynchronous response. The (1/2) × or (3/2) × harmoniccomponent rarely appears for small crack near the rotating speed ratio Ω = 2Ωc or Ω =(2/3)Ωc. In the case of supercritical rotating speed, the additional 0× harmonic component is increased as the crack increases. The bearing parameters affect greatly the occur-rence of the nonsynchronous responses by means of exerting innuence on the critical spedand the stabi1ity of the system. 展开更多
关键词 rotor DYNAMICS cracks rotors JOURNAL bearings DYNAMIC characteristics BEHAVIOR
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Rotor综合征合并HBsAg携带者1例 被引量:2
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作者 李平 《实用肝脏病杂志》 CAS 2013年第3期274-274,共1页
Rotor综合征(RS)为常染色体隐性遗传性疾病。临床少见且常易与其他肝病相混淆。现将我们诊治的1例报告如下。 病例摘要 患者男,26岁。因反复皮肤黄、眼黄26年于2012年8月1日入院。患者诉自幼即出现皮肤黄和眼黄,并持续存在,劳累后加... Rotor综合征(RS)为常染色体隐性遗传性疾病。临床少见且常易与其他肝病相混淆。现将我们诊治的1例报告如下。 病例摘要 患者男,26岁。因反复皮肤黄、眼黄26年于2012年8月1日入院。患者诉自幼即出现皮肤黄和眼黄,并持续存在,劳累后加深,不伴有皮肤瘙痒,无腹胀,纳差及肝区不适。2002年体检时发现HBsAg/HBeAb/HB cAb阳性, 展开更多
关键词 rotor综合征 HBSAG携带 先天性非溶血性黄疸
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