Plants and plant-based products are the bases of many modern pharmaceuticals that are current in use today for various diseases.The aim of the study was to investigate the biochemical constituents and high performance...Plants and plant-based products are the bases of many modern pharmaceuticals that are current in use today for various diseases.The aim of the study was to investigate the biochemical constituents and high performance thin layer chromatography(HPTLC) finger printing of the ethanolic extract of Evolvulus alsinoides.Phytochemical screening was done by standard procedures and HPTLC method was also established to analyze alkaloids,flavonoids and phenolic compounds from the ethanolic extract of Evolvulus alsinoides.Preliminary phytochemical screening showed that ethanol extracted more secondary metabolites than other solvents.HPTLC fingerprinting analysis showed the presence of various alkaloids,flavonoids and phenols(quercetin) in the ethanolic extract.It can be concluded that Evolvulus alsinoides may serve as a source of potent antioxidants that may be used in the prevention of various diseases such as cancer,diabetes and cardiovascular diseases due to the presence of phenolic compounds.HPTLC finger print of Evolvulus alsinoides may be useful in the differentiation of the species from adulterants and act as a biochemical marker for this medicinally important plant in the pharmaceutical industry and plant systematic studies.展开更多
We use the secondary relative benefit model based on DEA to evaluate the performance of agricultural financial expenditure in Guizhou Province, which can give due consideration to the production effectiveness determin...We use the secondary relative benefit model based on DEA to evaluate the performance of agricultural financial expenditure in Guizhou Province, which can give due consideration to the production effectiveness determined by objective natural conditions, and management effectiveness of all regions (as decision-making body) in the use of financial fund for supporting agriculture. In general, there is north-south gradient difference in the performance of financial support for agriculture between regions in Guizhou Province. The drought in 2010 has significant impact on the technical efficiency in the whole province; the performance score of each item in Liupanshui City and Southwest Guizhou is very low; the technical efficiency and management efficiency in most regions need to be improved. In order to improve the performance of financial support for agriculture, we need to ensure the scale of input; at the same time, provide appropriate preferential financial policies for agricultural infrastructure, especially the construction of rural water conservancy, development and promotion of agricultural science and technology, and other fields; adopt the way of special check and acceptance of supporting projects to strengthen the use management of the fund for agriculture.展开更多
背景:前交叉韧带重建后肌肉功能的恢复通常评估肌肉的最大力量,最近的研究认为还应考虑神经肌肉功能,比如肌肉等长发力率,即在肌肉等长收缩条件下测量不同时间间隔的力-时间曲线斜率。目的:阐述前交叉韧带重建后患者肌肉等长发力率的研...背景:前交叉韧带重建后肌肉功能的恢复通常评估肌肉的最大力量,最近的研究认为还应考虑神经肌肉功能,比如肌肉等长发力率,即在肌肉等长收缩条件下测量不同时间间隔的力-时间曲线斜率。目的:阐述前交叉韧带重建后患者肌肉等长发力率的研究现状与不足,分析术后不同时间内股四头肌和腘绳肌等长发力率的缺陷程度;等长发力率对术后患者功能表现的影响,为优化前交叉韧带重建后康复、减少患者二次损伤以及降低膝骨关节炎发生率提供重要信息。方法:检索中国知网、维普、万方和PubMed数据库,以“前交叉韧带,发力率”为中文检索词,以“anterior cruciate ligament,rate of force development,rate of torque development”为英文检索词,按照纳入和排除标准最终纳入69篇文献。结果与结论:(1)大多数研究发现前交叉韧带重建后半年内患者双侧肌肉等长发力率存在缺陷,双侧腘绳肌早期等长发力率(即肌肉收缩100 ms时间段内任意时间间隔的力-时间曲线斜率)在半年后有显著改善,但双侧股四头肌早期等长发力率长期缺陷,表明术后股四头肌神经肌肉功能长期受损。(2)有关晚期等长发力率(肌肉收缩100 ms后时间段内任意时间间隔的力-时间曲线斜率)的相关研究较少,无法得出确切结论。(3)关于着陆运动(跳跃落地和侧切等)和日常生活活动(走、跑),股四头肌早期等长发力率比等长峰值力矩相关性更强,运动过程中生物力学的异常改变被认为是患者二次损伤以及创伤性膝骨关节炎发生的重要风险因素,积极改善股四头肌早期等长发力率可能会降低二次损伤以及创伤性膝骨关节炎的发生率。(4)目前仅有很少的证据表明,全身振动训练能改善前交叉韧带重建后患者股四头肌早期等长发力率,建议今后在术后早期阶段应用神经肌肉电刺激干预股四头肌和腘绳肌,而在术后晚期阶段实施爆发力、高阻力训练,这可能会改善患者等长发力率。(5)短时间产生足够的肌肉力量才能有效保护前交叉韧带,而腘绳肌等长发力率与功能表现的关系尚不清楚,这可能会提供有关预防患者二次损伤的信息。(6)作者建议将等长发力率作为指导康复以及恢复运动的评估指标之一,除了关注对称性的改善以及与正常人的差异,还要考虑腘绳肌与股四头肌力量的比值,合适的比值范围才能保证肌肉快速发力时的平衡,这可能会降低再次损伤的发生,但比值的正常范围尚不清楚。(7)未来研究要考虑移植物类型和膝关节屈曲角度对等长发力率的影响,以尽可能找出患者存在的神经肌肉功能障碍,帮助患者更好地康复。展开更多
Elliptical tanks were used as an alternative to circular tanks in order to improve mixing efficiency and reduce mixing time in unbaffled stirred tanks(USTs). Five different aspect ratios of elliptical vessels were des...Elliptical tanks were used as an alternative to circular tanks in order to improve mixing efficiency and reduce mixing time in unbaffled stirred tanks(USTs). Five different aspect ratios of elliptical vessels were designed to compare their mixing time and flow field. Computational fluid dynamics(CFD) simulations were performed using the k–ε model to calculate the mixing time and simulate turbulent flow field features, such as streamline shape, velocity distribution, vortex core region distribution, and turbulent kinetic energy(TKE) transfer. Visualization was also carried out to track the tinctorial evolution of the liquid phase. Results reveal that elliptical stirred tanks can significantly improve mixing performance in USTs. Specifically, the mixing time at an aspect ratio of 2.00 is only 45.3% of the one of a circular stirred tank. Furthermore, the secondary flow is strengthened and the vortex core region increases with the increase of aspect ratio. The axial velocity is more sensitive to the aspect ratio than the circumferential and radial velocity. Additionally, the TKE transfer in elliptical vessels is altered. These findings suggest that elliptical vessels offer a promising alternative to circular vessels for enhancing mixing performance in USTs.展开更多
近年来,医疗机构陆续建立以公益性为导向的绩效分配制度,充分利用以资源为基础的相对价值比率(resource-based relative value scale,RBRVS)等方法和经验,将技术水平、疑难系数、工作质量、患者满意度等作为绩效分配重点考核指标,使医...近年来,医疗机构陆续建立以公益性为导向的绩效分配制度,充分利用以资源为基础的相对价值比率(resource-based relative value scale,RBRVS)等方法和经验,将技术水平、疑难系数、工作质量、患者满意度等作为绩效分配重点考核指标,使医务人员收入真正体现劳动价值和技术价值,实现优绩优酬。口腔专科医院具有“大门诊小病房”特色,口腔患者更需要一个团队为其提供优质、有效的个体化综合性治疗方案。文章以口腔正畸学科为例,重点分析某口腔医院在实行绩效二次分配过程中遇到的痛点及难点,旨在多维度探讨主诊医师负责制在口腔专科医院的应用,加快推进绩效核算在二次分配层面的落实,提升工作积极性,实现医务人员及患者的“双满意”。展开更多
文摘Plants and plant-based products are the bases of many modern pharmaceuticals that are current in use today for various diseases.The aim of the study was to investigate the biochemical constituents and high performance thin layer chromatography(HPTLC) finger printing of the ethanolic extract of Evolvulus alsinoides.Phytochemical screening was done by standard procedures and HPTLC method was also established to analyze alkaloids,flavonoids and phenolic compounds from the ethanolic extract of Evolvulus alsinoides.Preliminary phytochemical screening showed that ethanol extracted more secondary metabolites than other solvents.HPTLC fingerprinting analysis showed the presence of various alkaloids,flavonoids and phenols(quercetin) in the ethanolic extract.It can be concluded that Evolvulus alsinoides may serve as a source of potent antioxidants that may be used in the prevention of various diseases such as cancer,diabetes and cardiovascular diseases due to the presence of phenolic compounds.HPTLC finger print of Evolvulus alsinoides may be useful in the differentiation of the species from adulterants and act as a biochemical marker for this medicinally important plant in the pharmaceutical industry and plant systematic studies.
基金Key Chongqing Municipal Humanities and Social Sciences Research Base Project in Southwest University(SWU0810026)the Fundamental Research Funds for the Central Universities(SWU1209457 and SWU0909510)+5 种基金National Soft Science Fund(2007GXS3D094)Youth Fund Project of Southwest Normal University(SWU07106)Chongqing Soft Science Project(CSTC,2009CE9016)2012 Shizhu Base Science and Technology Innovation Special Fund Projects(sz201208)National Social Science Fund Project(12ASH00412AGL008)
文摘We use the secondary relative benefit model based on DEA to evaluate the performance of agricultural financial expenditure in Guizhou Province, which can give due consideration to the production effectiveness determined by objective natural conditions, and management effectiveness of all regions (as decision-making body) in the use of financial fund for supporting agriculture. In general, there is north-south gradient difference in the performance of financial support for agriculture between regions in Guizhou Province. The drought in 2010 has significant impact on the technical efficiency in the whole province; the performance score of each item in Liupanshui City and Southwest Guizhou is very low; the technical efficiency and management efficiency in most regions need to be improved. In order to improve the performance of financial support for agriculture, we need to ensure the scale of input; at the same time, provide appropriate preferential financial policies for agricultural infrastructure, especially the construction of rural water conservancy, development and promotion of agricultural science and technology, and other fields; adopt the way of special check and acceptance of supporting projects to strengthen the use management of the fund for agriculture.
文摘背景:前交叉韧带重建后肌肉功能的恢复通常评估肌肉的最大力量,最近的研究认为还应考虑神经肌肉功能,比如肌肉等长发力率,即在肌肉等长收缩条件下测量不同时间间隔的力-时间曲线斜率。目的:阐述前交叉韧带重建后患者肌肉等长发力率的研究现状与不足,分析术后不同时间内股四头肌和腘绳肌等长发力率的缺陷程度;等长发力率对术后患者功能表现的影响,为优化前交叉韧带重建后康复、减少患者二次损伤以及降低膝骨关节炎发生率提供重要信息。方法:检索中国知网、维普、万方和PubMed数据库,以“前交叉韧带,发力率”为中文检索词,以“anterior cruciate ligament,rate of force development,rate of torque development”为英文检索词,按照纳入和排除标准最终纳入69篇文献。结果与结论:(1)大多数研究发现前交叉韧带重建后半年内患者双侧肌肉等长发力率存在缺陷,双侧腘绳肌早期等长发力率(即肌肉收缩100 ms时间段内任意时间间隔的力-时间曲线斜率)在半年后有显著改善,但双侧股四头肌早期等长发力率长期缺陷,表明术后股四头肌神经肌肉功能长期受损。(2)有关晚期等长发力率(肌肉收缩100 ms后时间段内任意时间间隔的力-时间曲线斜率)的相关研究较少,无法得出确切结论。(3)关于着陆运动(跳跃落地和侧切等)和日常生活活动(走、跑),股四头肌早期等长发力率比等长峰值力矩相关性更强,运动过程中生物力学的异常改变被认为是患者二次损伤以及创伤性膝骨关节炎发生的重要风险因素,积极改善股四头肌早期等长发力率可能会降低二次损伤以及创伤性膝骨关节炎的发生率。(4)目前仅有很少的证据表明,全身振动训练能改善前交叉韧带重建后患者股四头肌早期等长发力率,建议今后在术后早期阶段应用神经肌肉电刺激干预股四头肌和腘绳肌,而在术后晚期阶段实施爆发力、高阻力训练,这可能会改善患者等长发力率。(5)短时间产生足够的肌肉力量才能有效保护前交叉韧带,而腘绳肌等长发力率与功能表现的关系尚不清楚,这可能会提供有关预防患者二次损伤的信息。(6)作者建议将等长发力率作为指导康复以及恢复运动的评估指标之一,除了关注对称性的改善以及与正常人的差异,还要考虑腘绳肌与股四头肌力量的比值,合适的比值范围才能保证肌肉快速发力时的平衡,这可能会降低再次损伤的发生,但比值的正常范围尚不清楚。(7)未来研究要考虑移植物类型和膝关节屈曲角度对等长发力率的影响,以尽可能找出患者存在的神经肌肉功能障碍,帮助患者更好地康复。
基金supported by the National Key Research and Development Project(2022YFB3504305,2019YFC1905802)National Natural Science Foundation of China(22078030)+2 种基金Joint Funds of the National Natural Science Foundation of China(U1802255)Key Project of Independent Research Project of State Key Laboratory of Coal Mine Disaster Dynamics and Control(2011DA105287-zd201902)Three Gorges Laboratory Open Fund of Hubei Province(SK211009,SK215001).
文摘Elliptical tanks were used as an alternative to circular tanks in order to improve mixing efficiency and reduce mixing time in unbaffled stirred tanks(USTs). Five different aspect ratios of elliptical vessels were designed to compare their mixing time and flow field. Computational fluid dynamics(CFD) simulations were performed using the k–ε model to calculate the mixing time and simulate turbulent flow field features, such as streamline shape, velocity distribution, vortex core region distribution, and turbulent kinetic energy(TKE) transfer. Visualization was also carried out to track the tinctorial evolution of the liquid phase. Results reveal that elliptical stirred tanks can significantly improve mixing performance in USTs. Specifically, the mixing time at an aspect ratio of 2.00 is only 45.3% of the one of a circular stirred tank. Furthermore, the secondary flow is strengthened and the vortex core region increases with the increase of aspect ratio. The axial velocity is more sensitive to the aspect ratio than the circumferential and radial velocity. Additionally, the TKE transfer in elliptical vessels is altered. These findings suggest that elliptical vessels offer a promising alternative to circular vessels for enhancing mixing performance in USTs.
文摘近年来,医疗机构陆续建立以公益性为导向的绩效分配制度,充分利用以资源为基础的相对价值比率(resource-based relative value scale,RBRVS)等方法和经验,将技术水平、疑难系数、工作质量、患者满意度等作为绩效分配重点考核指标,使医务人员收入真正体现劳动价值和技术价值,实现优绩优酬。口腔专科医院具有“大门诊小病房”特色,口腔患者更需要一个团队为其提供优质、有效的个体化综合性治疗方案。文章以口腔正畸学科为例,重点分析某口腔医院在实行绩效二次分配过程中遇到的痛点及难点,旨在多维度探讨主诊医师负责制在口腔专科医院的应用,加快推进绩效核算在二次分配层面的落实,提升工作积极性,实现医务人员及患者的“双满意”。
