Objective:To investigate the clinical efficacy and safety of Chuzhi Shengfa Tablets combined with ketoconazole shampoo and Chuzhi Shengfa Tablets combined with 5%minoxidil foam in the treatment of male androgenetic al...Objective:To investigate the clinical efficacy and safety of Chuzhi Shengfa Tablets combined with ketoconazole shampoo and Chuzhi Shengfa Tablets combined with 5%minoxidil foam in the treatment of male androgenetic alopecia.Methods:From July 2022 to July 2023,120 male patients with androgenetic alopecia were selected from our Department of Dermatology and randomly divided into Control Group 1,Control Group 2,Observation Group 1,and Observation Group 2,with 30 patients in each group.Control Group 1 was treated with ketoconazole shampoo,Control Group 2 with 5%minoxidil foam,Observation Group 1 with ketoconazole shampoo combined with Chuzhi Shengfa Tablets,and Observation Group 2 with 5%minoxidil foam combined with Chuzhi Shengfa Tablets.Hair density,hair diameter,scalp oil secretion(using oil secretion scoring),and adverse reactions were compared before and after treatment across the four groups.Results:After treatment,hair density and hair diameter significantly increased in all four groups compared to before treatment,while scalp oil secretion scores significantly decreased(P<0.05).The improvements in Observation Groups 1 and 2 were significantly better than those in Control Groups 1 and 2(P<0.05).No significant differences in the incidence of adverse reactions were observed among the four groups(P>0.05).Conclusion:Chuzhi Shengfa Tablets combined with ketoconazole shampoo and Chuzhi Shengfa Tablets combined with 5%minoxidil foam are both effective and safe for treating male androgenetic alopecia.These combinations can significantly improve hair growth and are worthy of clinical promotion.展开更多
The contamination of shampoo with bacteria is not very common but can happen and can be a potential cause of conjunctivitis. This case report describes a 24-year-old male who developed conjunctivitis after using a Ser...The contamination of shampoo with bacteria is not very common but can happen and can be a potential cause of conjunctivitis. This case report describes a 24-year-old male who developed conjunctivitis after using a Serratia marcescens contaminated shampoo in a fitness club. The patient had redness, swelling, and discharge in both eyes. Cultures of the shampoo and eye swabs were positive for S. marcescens with indistinguishable DNA fingerprints. The patient was treated with an eye drop antibiotic and his symptoms resolved within a week. This case highlights the possibility of exposure in places where shampoos containers are refilled or shared. The avoidance of refilling them and using replaceable cartridges, single-sealed refill bags, or bringing personal shampoo is highly recommended to prevent such incidents.展开更多
Objective: To evaluate the efficacy of Thai herbal shampoos [Cartoxylum formosum(C.formosum) + eucalyptus essential oil(EO), C. formosum + citrus EO, Solanum trilobatum+ eucalyptus EO, Solanum trilobatum + citrus EO, ...Objective: To evaluate the efficacy of Thai herbal shampoos [Cartoxylum formosum(C.formosum) + eucalyptus essential oil(EO), C. formosum + citrus EO, Solanum trilobatum+ eucalyptus EO, Solanum trilobatum + citrus EO, Moringa oleifera + eucalyptus EO and Moringa oleifera + citrus EO] for killing all stages of Pediculus humanus capitis(Phthiraptera).Methods: A filter paper contact method was applied with three concentrations(0.05, 0.10 and 0.20 mL/cm^2) of each Thai herbal shampoo as well as permethrin pediculicide(positive control) and drinking water(negative control) against eggs, nymphs and adults of Pediculus humanus capitis. Mortality rates of the eggs were recorded after 7 days of incubation while those of nymphs and adults were recorded after 5 minutes of contact. Results: All herbal shampoos at the high concentration were highly effective against nymphs and adults, but not effective against the eggs. C. formosum + eucalyptus EO and C. formosum + citrus EO shampoos at all concentrations exhibited the highest efficacy against nymphs and adults with100% mortality rate at 5 min and LC_(50) values of 0.004 and 0.005 mL/cm^2, respectively. All formulation of Solanum trilobatum and Moringa oleifera shampoos added with eucalyptus EO showed mortality rates against nymphs at 92.0%-100.0% and 76.0%-100.0% and against adults at 84.0%-100.0% and 20.0%-32.0%, respectively. Permethrin pediculicide was not effective against the eggs, but showed 68.0%-92.0% and 28.0%-60.0% mortality rates against nymphs and adults. Conclusions: These results indicate that C. formosum + eucalyptus EO shampoo can be used as an effective nymphicide and adulticide against Pediculus humanus capitis.展开更多
Background/Aim: Dandruff is a common scalp problem associated with flaky and inflamed skin. In this study, we investigated the efficacy of a shampoo containing piroctone olamine and climbazole and the combination of t...Background/Aim: Dandruff is a common scalp problem associated with flaky and inflamed skin. In this study, we investigated the efficacy of a shampoo containing piroctone olamine and climbazole and the combination of this shampoo with a scalp tonic containing piroctone olamine and licochalcone A, derived from Glycyrrhiza inflata root extract, to reduce dandruff. Study Design/Methods: After conditioning, 102 subjects (♂ 56 and 46 ♀) with moderate to very strong dandruff affection underwent a randomized half head study for 4 weeks. The volunteers’ heads were washed regularly either with a placebo or the anti-dandruff shampoo, followed by the anti-dandruff tonic application or no treatment. In a 2-week post-treatment phase, subjects only applied placebo shampoo. Every two weeks, trained experts assessed dandruff affection based on a scale of 1 to 6. At study start and after every 2 weeks, cytokine concentrations and anti-fungal activity of test products were determined in scalp wash-ups by enzyme-linked immunosorbant assays or a Malassezia colony-forming assay, respectively. Results: Results of expert grading and anti-fungal activity revealed a significant reduction in dandruff affection and Malassezia colony-forming units after treatment with the anti-dandruff shampoo or its combination with the tonic. Dandruff affection even remained reduced in the post-treatment phase when levels of Malassezia colony-forming units had returned to baseline. Cytokine analyses proved a significant decrease in pro-inflammatory dandruff markers after treatment with both anti-dandruff products. For the shampoo/tonic combination, a superior reduction of one scalp inflammatory marker was determined even after the post-treatment phase. Conclusion: Both the rinse-off shampoo as well as its combination with the leave-on tonic excellently alleviated dandruff and its associated micro-inflammation. Both treatments showed anti-fungal activity. The superior benefit, exerted by the combination, is primarily based on the known anti-inflammatory effect of licochalcone A and the improved scalp substantivity of the leave-on application.展开更多
Patimas shampoos are three in one——Shampoo,tonic and moisturizer. The shampoo contains the essence ofnatural flowers and Chinese traditionalmedicinal herbs,and are matched with naturalcomposition for stopping itches...Patimas shampoos are three in one——Shampoo,tonic and moisturizer. The shampoo contains the essence ofnatural flowers and Chinese traditionalmedicinal herbs,and are matched with naturalcomposition for stopping itches,removingdandruff and stimulating blood circulation.展开更多
表观故事Cover story 露华浓公司在其已有的名为Colorstay系列产品中又添加了一个新品Stay Natural Concealer,一种轻质、可混合的液体遮瑕粉底液。该新产品据说可以提供自然的遮盖效果,并且由于其配方中采用了柔软的硅酮球体,使得遮瑕...表观故事Cover story 露华浓公司在其已有的名为Colorstay系列产品中又添加了一个新品Stay Natural Concealer,一种轻质、可混合的液体遮瑕粉底液。该新产品据说可以提供自然的遮盖效果,并且由于其配方中采用了柔软的硅酮球体,使得遮瑕效果可以持续16小时以上。展开更多
The effects of pH and water hardness on the foaming properties of sodium methyl cocoyl taurate and its performance in combination with zwitterionic surfactants were investigated.The irritation of sodium methyl cocoyl ...The effects of pH and water hardness on the foaming properties of sodium methyl cocoyl taurate and its performance in combination with zwitterionic surfactants were investigated.The irritation of sodium methyl cocoyl taurate and its application in a shampoo formula were also studied.According to the result of experiment,sodium methyl cocoyl taurate had a wide pH stability range and good resistance to hard water,and it showed good synergistic thickening effect with betaine surfactants,especially when mixed with acyl hydroxysulfo betaine;The skin cholesterol dissolution test and red blood cell hemolysis test showed that its irritation was very low.Sodium methyl cocoyl taurate was applied to the transparent shampoo formula,and the sulfate-free transparent shampoo thus prepared had good stability and low eye irritation.It was both mild and non-irritating to skin.展开更多
An in vitro biological model for evaluation of the anti-dandruff performance of hair care products was established. In this model, Malasseziafurfur(M.furfur) was used as indicator bacteria with pigskin as substrate.Th...An in vitro biological model for evaluation of the anti-dandruff performance of hair care products was established. In this model, Malasseziafurfur(M.furfur) was used as indicator bacteria with pigskin as substrate.This model functions in following steps: pretreatment for the substrate; inoculation of indicator bacteria;measuring the bacteriostatic efficacy by the contact plates after washing the pigskin with the sample shampoo;calculation of the effective index P; evaluation of the anti-dandruff performance by the effective index P. Three kinds of anti-dandruff agents including BPT, ZPT and OCT were tested by the model. Results showed that the order for antibacterial efficacy of the anti-dandruff agents within the mass fraction range of 0.1 %~2.0% was BPT>ZPT>OCT. Results of the evaluation on each type of shampoo showed that: one displays no antidandruff efficacy; three displays medium anti-dandruff efficacy; two displays strong anti-dandruff efficacy.展开更多
Take Everything Alison: Shall we go swimming today? Richard: Sure. Let's go and have fun! Alison: What should we take with us? Richard: Let me think... Swimming suits! Alison: Wait, let me take clean towels, slipp...Take Everything Alison: Shall we go swimming today? Richard: Sure. Let's go and have fun! Alison: What should we take with us? Richard: Let me think... Swimming suits! Alison: Wait, let me take clean towels, slippers... Richard: OK. That's all. Shall we go? Alison: Wait, I still need some shampoo, soap, lotion and... Richard: Oh my god. How many things do you need anyway? Alison: Let me think it over. They're all necessary.展开更多
文摘Objective:To investigate the clinical efficacy and safety of Chuzhi Shengfa Tablets combined with ketoconazole shampoo and Chuzhi Shengfa Tablets combined with 5%minoxidil foam in the treatment of male androgenetic alopecia.Methods:From July 2022 to July 2023,120 male patients with androgenetic alopecia were selected from our Department of Dermatology and randomly divided into Control Group 1,Control Group 2,Observation Group 1,and Observation Group 2,with 30 patients in each group.Control Group 1 was treated with ketoconazole shampoo,Control Group 2 with 5%minoxidil foam,Observation Group 1 with ketoconazole shampoo combined with Chuzhi Shengfa Tablets,and Observation Group 2 with 5%minoxidil foam combined with Chuzhi Shengfa Tablets.Hair density,hair diameter,scalp oil secretion(using oil secretion scoring),and adverse reactions were compared before and after treatment across the four groups.Results:After treatment,hair density and hair diameter significantly increased in all four groups compared to before treatment,while scalp oil secretion scores significantly decreased(P<0.05).The improvements in Observation Groups 1 and 2 were significantly better than those in Control Groups 1 and 2(P<0.05).No significant differences in the incidence of adverse reactions were observed among the four groups(P>0.05).Conclusion:Chuzhi Shengfa Tablets combined with ketoconazole shampoo and Chuzhi Shengfa Tablets combined with 5%minoxidil foam are both effective and safe for treating male androgenetic alopecia.These combinations can significantly improve hair growth and are worthy of clinical promotion.
文摘The contamination of shampoo with bacteria is not very common but can happen and can be a potential cause of conjunctivitis. This case report describes a 24-year-old male who developed conjunctivitis after using a Serratia marcescens contaminated shampoo in a fitness club. The patient had redness, swelling, and discharge in both eyes. Cultures of the shampoo and eye swabs were positive for S. marcescens with indistinguishable DNA fingerprints. The patient was treated with an eye drop antibiotic and his symptoms resolved within a week. This case highlights the possibility of exposure in places where shampoos containers are refilled or shared. The avoidance of refilling them and using replaceable cartridges, single-sealed refill bags, or bringing personal shampoo is highly recommended to prevent such incidents.
基金supported by King Mongkut's Institute of Technology Ladkrabang,Ladkrabang,Bangkok 10520,Thailand(Grant No.2560-01-04-003)the National Research Council of Thailand(Grant for the Doctoral Degree Student Fly 2016)
文摘Objective: To evaluate the efficacy of Thai herbal shampoos [Cartoxylum formosum(C.formosum) + eucalyptus essential oil(EO), C. formosum + citrus EO, Solanum trilobatum+ eucalyptus EO, Solanum trilobatum + citrus EO, Moringa oleifera + eucalyptus EO and Moringa oleifera + citrus EO] for killing all stages of Pediculus humanus capitis(Phthiraptera).Methods: A filter paper contact method was applied with three concentrations(0.05, 0.10 and 0.20 mL/cm^2) of each Thai herbal shampoo as well as permethrin pediculicide(positive control) and drinking water(negative control) against eggs, nymphs and adults of Pediculus humanus capitis. Mortality rates of the eggs were recorded after 7 days of incubation while those of nymphs and adults were recorded after 5 minutes of contact. Results: All herbal shampoos at the high concentration were highly effective against nymphs and adults, but not effective against the eggs. C. formosum + eucalyptus EO and C. formosum + citrus EO shampoos at all concentrations exhibited the highest efficacy against nymphs and adults with100% mortality rate at 5 min and LC_(50) values of 0.004 and 0.005 mL/cm^2, respectively. All formulation of Solanum trilobatum and Moringa oleifera shampoos added with eucalyptus EO showed mortality rates against nymphs at 92.0%-100.0% and 76.0%-100.0% and against adults at 84.0%-100.0% and 20.0%-32.0%, respectively. Permethrin pediculicide was not effective against the eggs, but showed 68.0%-92.0% and 28.0%-60.0% mortality rates against nymphs and adults. Conclusions: These results indicate that C. formosum + eucalyptus EO shampoo can be used as an effective nymphicide and adulticide against Pediculus humanus capitis.
文摘Background/Aim: Dandruff is a common scalp problem associated with flaky and inflamed skin. In this study, we investigated the efficacy of a shampoo containing piroctone olamine and climbazole and the combination of this shampoo with a scalp tonic containing piroctone olamine and licochalcone A, derived from Glycyrrhiza inflata root extract, to reduce dandruff. Study Design/Methods: After conditioning, 102 subjects (♂ 56 and 46 ♀) with moderate to very strong dandruff affection underwent a randomized half head study for 4 weeks. The volunteers’ heads were washed regularly either with a placebo or the anti-dandruff shampoo, followed by the anti-dandruff tonic application or no treatment. In a 2-week post-treatment phase, subjects only applied placebo shampoo. Every two weeks, trained experts assessed dandruff affection based on a scale of 1 to 6. At study start and after every 2 weeks, cytokine concentrations and anti-fungal activity of test products were determined in scalp wash-ups by enzyme-linked immunosorbant assays or a Malassezia colony-forming assay, respectively. Results: Results of expert grading and anti-fungal activity revealed a significant reduction in dandruff affection and Malassezia colony-forming units after treatment with the anti-dandruff shampoo or its combination with the tonic. Dandruff affection even remained reduced in the post-treatment phase when levels of Malassezia colony-forming units had returned to baseline. Cytokine analyses proved a significant decrease in pro-inflammatory dandruff markers after treatment with both anti-dandruff products. For the shampoo/tonic combination, a superior reduction of one scalp inflammatory marker was determined even after the post-treatment phase. Conclusion: Both the rinse-off shampoo as well as its combination with the leave-on tonic excellently alleviated dandruff and its associated micro-inflammation. Both treatments showed anti-fungal activity. The superior benefit, exerted by the combination, is primarily based on the known anti-inflammatory effect of licochalcone A and the improved scalp substantivity of the leave-on application.
文摘Patimas shampoos are three in one——Shampoo,tonic and moisturizer. The shampoo contains the essence ofnatural flowers and Chinese traditionalmedicinal herbs,and are matched with naturalcomposition for stopping itches,removingdandruff and stimulating blood circulation.
文摘The effects of pH and water hardness on the foaming properties of sodium methyl cocoyl taurate and its performance in combination with zwitterionic surfactants were investigated.The irritation of sodium methyl cocoyl taurate and its application in a shampoo formula were also studied.According to the result of experiment,sodium methyl cocoyl taurate had a wide pH stability range and good resistance to hard water,and it showed good synergistic thickening effect with betaine surfactants,especially when mixed with acyl hydroxysulfo betaine;The skin cholesterol dissolution test and red blood cell hemolysis test showed that its irritation was very low.Sodium methyl cocoyl taurate was applied to the transparent shampoo formula,and the sulfate-free transparent shampoo thus prepared had good stability and low eye irritation.It was both mild and non-irritating to skin.
文摘An in vitro biological model for evaluation of the anti-dandruff performance of hair care products was established. In this model, Malasseziafurfur(M.furfur) was used as indicator bacteria with pigskin as substrate.This model functions in following steps: pretreatment for the substrate; inoculation of indicator bacteria;measuring the bacteriostatic efficacy by the contact plates after washing the pigskin with the sample shampoo;calculation of the effective index P; evaluation of the anti-dandruff performance by the effective index P. Three kinds of anti-dandruff agents including BPT, ZPT and OCT were tested by the model. Results showed that the order for antibacterial efficacy of the anti-dandruff agents within the mass fraction range of 0.1 %~2.0% was BPT>ZPT>OCT. Results of the evaluation on each type of shampoo showed that: one displays no antidandruff efficacy; three displays medium anti-dandruff efficacy; two displays strong anti-dandruff efficacy.
文摘Take Everything Alison: Shall we go swimming today? Richard: Sure. Let's go and have fun! Alison: What should we take with us? Richard: Let me think... Swimming suits! Alison: Wait, let me take clean towels, slippers... Richard: OK. That's all. Shall we go? Alison: Wait, I still need some shampoo, soap, lotion and... Richard: Oh my god. How many things do you need anyway? Alison: Let me think it over. They're all necessary.
