<strong>Rationale:</strong> The three-dimensional (3D) computer-made titanium mesh is widely used in the skull repair for those patients receiving decompression of the bone flap. It can restore normal anat...<strong>Rationale:</strong> The three-dimensional (3D) computer-made titanium mesh is widely used in the skull repair for those patients receiving decompression of the bone flap. It can restore normal anatomy to a greater extent and make a better appearance. <strong>Case Presentation: </strong>We reported two cases of patients admitted to our hospital who have experienced high scalp tension after skull repair. At first, these two patients underwent decompression of the bone flap, and the physical examination results showed a defect of skull. No neurological symptoms and signs were found. The 3D computed tomography (CT) reconstruction of skull was performed, and then the skull repair with 3D titanium mesh was conducted. But because of high scalp tension, they underwent a second operation, during which we re-trimmed and reduce the arc of the titanium mesh. The scalp incision of both patients healed well and no titanium mesh was exposed. Both patients have a good prognosis. <strong>Lessons:</strong> We highlight that the high tension of scalp due to overstretching after 3D titanium mesh repair for skull defect should be paid much attention to. Trimming and reducing the arc of titanium mesh is an effective treatment for this situation.展开更多
背景:神经内镜经鼻蝶手术因其微创、显露充分、术后恢复快等特点,已成为前颅底中线及侧颅底占位最常用的手术方式。随着手术范围及适应证也的不断扩展,颅底磨除范围相应增加,这也使术后脑脊液漏发生率也相应增高。严重的脑脊液漏可导致...背景:神经内镜经鼻蝶手术因其微创、显露充分、术后恢复快等特点,已成为前颅底中线及侧颅底占位最常用的手术方式。随着手术范围及适应证也的不断扩展,颅底磨除范围相应增加,这也使术后脑脊液漏发生率也相应增高。严重的脑脊液漏可导致患者致命性的颅内感染及极差的预后。因此在神经内镜手术后,可靠的颅底重建是手术成功的基本条件,文章以此对颅底重建原则、方法、颅底重建应用的不同材料的生物学特性等展开综述。目的:阐述颅底重建的原则方法,总结不同重建材料的研究进展及不同生物学特性在颅底重建中的作用。方法:计算机检索万方及PubMed数据库2012年1月至2022年1月收录的文献,中文检索词为“颅底重建、神经内镜、颅底骨缺损、经鼻蝶手术入路、多重修补、带蒂黏膜瓣、聚醚醚酮、羟基磷灰石”,英文检索词为“Skull base reconstruction,Neuroendoscopy,Skull base bone defect,Transnasal-sphenoidal operative approach,Multiple repair,Pedicled mucosal flap,Polyether-ether-ketone(PEEK),Hydroxylapatite”,最终纳入60篇文献进行综述。结果与结论:(1)神经内镜经鼻蝶术后,即使颅底缺损越来越大,颅底重建的目地依旧是预防脑脊液漏避免严重并发症,目前多层修补是一致认可的修复原则。(2)骨性支撑的类骨材料诸如聚醚醚酮、羟基磷灰石因为价格昂贵且术前准备繁琐,临床应用较少;临床医生多靠类硬膜结构的生物材料及带蒂黏膜瓣完成修补,但受限于修补支撑力弱及黏膜瓣血运情况,少数病患仍有一定概率存在脑脊液漏的风险。(3)因此,术中类硬膜、类骨结构人工生物材料以及带蒂黏膜瓣修补颅底缺损符合恢复颅底的解剖修复,有助于硬膜、骨质结构的再生,这样也使疏水组织-类硬膜结构-类骨结构-黏膜的一体化生物材料研发具有广阔的应用前景。展开更多
目的:研究分析脑室腹腔分流术配合不同时期颅骨修补治疗创伤性颅脑外伤的临床疗效及对患者神经功能的影响。方法:86例创伤性颅脑外伤患者,根据颅骨修补时期的不同分为对照组和观察组,每组各43例。对照组患者脑室腹腔分流术后3个月行颅...目的:研究分析脑室腹腔分流术配合不同时期颅骨修补治疗创伤性颅脑外伤的临床疗效及对患者神经功能的影响。方法:86例创伤性颅脑外伤患者,根据颅骨修补时期的不同分为对照组和观察组,每组各43例。对照组患者脑室腹腔分流术后3个月行颅骨修补术,观察组患者在实施脑室腹腔分流术同期给予颅骨缺损修补术治疗。比较两组临床疗效、并发症以及手术前、后活动能力和神经功能。结果:观察组临床疗效97.67%,高于对照组的76.74%,差异有统计学意义(P<0.05);观察组患者术前的ADL及Fugl-Meyer评分与对照组相比,差异无统计学意义(P>0.05);术后30 d,两组患者的ADL及Fugl-Meyer评分均较术前提高显著,且观察组上升幅度更大,差异有统计学意义(P<0.05);观察组术后15 d、30 d NIHSS评分比对照组低,差异有统计学意义(P<0.05);观察组术后并发症发生率11.63%低于对照组的27.91%,差异有统计学意义(P<0.05)。结论:创伤性颅脑损伤患者给予颅骨缺损修补术联合早期脑室腹腔分流术治疗效果确切,有助于改善患者日常活动能力和四肢运动功能,促进神经功能恢复,减少并发症发生,利于预后,值得积极应用推广。展开更多
文摘<strong>Rationale:</strong> The three-dimensional (3D) computer-made titanium mesh is widely used in the skull repair for those patients receiving decompression of the bone flap. It can restore normal anatomy to a greater extent and make a better appearance. <strong>Case Presentation: </strong>We reported two cases of patients admitted to our hospital who have experienced high scalp tension after skull repair. At first, these two patients underwent decompression of the bone flap, and the physical examination results showed a defect of skull. No neurological symptoms and signs were found. The 3D computed tomography (CT) reconstruction of skull was performed, and then the skull repair with 3D titanium mesh was conducted. But because of high scalp tension, they underwent a second operation, during which we re-trimmed and reduce the arc of the titanium mesh. The scalp incision of both patients healed well and no titanium mesh was exposed. Both patients have a good prognosis. <strong>Lessons:</strong> We highlight that the high tension of scalp due to overstretching after 3D titanium mesh repair for skull defect should be paid much attention to. Trimming and reducing the arc of titanium mesh is an effective treatment for this situation.
文摘背景:神经内镜经鼻蝶手术因其微创、显露充分、术后恢复快等特点,已成为前颅底中线及侧颅底占位最常用的手术方式。随着手术范围及适应证也的不断扩展,颅底磨除范围相应增加,这也使术后脑脊液漏发生率也相应增高。严重的脑脊液漏可导致患者致命性的颅内感染及极差的预后。因此在神经内镜手术后,可靠的颅底重建是手术成功的基本条件,文章以此对颅底重建原则、方法、颅底重建应用的不同材料的生物学特性等展开综述。目的:阐述颅底重建的原则方法,总结不同重建材料的研究进展及不同生物学特性在颅底重建中的作用。方法:计算机检索万方及PubMed数据库2012年1月至2022年1月收录的文献,中文检索词为“颅底重建、神经内镜、颅底骨缺损、经鼻蝶手术入路、多重修补、带蒂黏膜瓣、聚醚醚酮、羟基磷灰石”,英文检索词为“Skull base reconstruction,Neuroendoscopy,Skull base bone defect,Transnasal-sphenoidal operative approach,Multiple repair,Pedicled mucosal flap,Polyether-ether-ketone(PEEK),Hydroxylapatite”,最终纳入60篇文献进行综述。结果与结论:(1)神经内镜经鼻蝶术后,即使颅底缺损越来越大,颅底重建的目地依旧是预防脑脊液漏避免严重并发症,目前多层修补是一致认可的修复原则。(2)骨性支撑的类骨材料诸如聚醚醚酮、羟基磷灰石因为价格昂贵且术前准备繁琐,临床应用较少;临床医生多靠类硬膜结构的生物材料及带蒂黏膜瓣完成修补,但受限于修补支撑力弱及黏膜瓣血运情况,少数病患仍有一定概率存在脑脊液漏的风险。(3)因此,术中类硬膜、类骨结构人工生物材料以及带蒂黏膜瓣修补颅底缺损符合恢复颅底的解剖修复,有助于硬膜、骨质结构的再生,这样也使疏水组织-类硬膜结构-类骨结构-黏膜的一体化生物材料研发具有广阔的应用前景。
文摘目的:研究分析脑室腹腔分流术配合不同时期颅骨修补治疗创伤性颅脑外伤的临床疗效及对患者神经功能的影响。方法:86例创伤性颅脑外伤患者,根据颅骨修补时期的不同分为对照组和观察组,每组各43例。对照组患者脑室腹腔分流术后3个月行颅骨修补术,观察组患者在实施脑室腹腔分流术同期给予颅骨缺损修补术治疗。比较两组临床疗效、并发症以及手术前、后活动能力和神经功能。结果:观察组临床疗效97.67%,高于对照组的76.74%,差异有统计学意义(P<0.05);观察组患者术前的ADL及Fugl-Meyer评分与对照组相比,差异无统计学意义(P>0.05);术后30 d,两组患者的ADL及Fugl-Meyer评分均较术前提高显著,且观察组上升幅度更大,差异有统计学意义(P<0.05);观察组术后15 d、30 d NIHSS评分比对照组低,差异有统计学意义(P<0.05);观察组术后并发症发生率11.63%低于对照组的27.91%,差异有统计学意义(P<0.05)。结论:创伤性颅脑损伤患者给予颅骨缺损修补术联合早期脑室腹腔分流术治疗效果确切,有助于改善患者日常活动能力和四肢运动功能,促进神经功能恢复,减少并发症发生,利于预后,值得积极应用推广。
