A growing number of studies have demonstrated that repeated exposure to sevoflurane during development results in persistent social abnormalities and cognitive impairment.Davunetide,an active fragment of the activity-...A growing number of studies have demonstrated that repeated exposure to sevoflurane during development results in persistent social abnormalities and cognitive impairment.Davunetide,an active fragment of the activity-dependent neuroprotective protein(ADNP),has been implicated in social and cognitive protection.However,the potential of davunetide to attenuate social deficits following sevoflurane exposure and the underlying developmental mechanisms remain poorly understood.In this study,ribosome and proteome profiles were analyzed to investigate the molecular basis of sevoflurane-induced social deficits in neonatal mice.The neuropathological basis was also explored using Golgi staining,morphological analysis,western blotting,electrophysiological analysis,and behavioral analysis.Results indicated that ADNP was significantly down-regulated following developmental exposure to sevoflurane.In adulthood,anterior cingulate cortex(ACC)neurons exposed to sevoflurane exhibited a decrease in dendrite number,total dendrite length,and spine density.Furthermore,the expression levels of Homer,PSD95,synaptophysin,and vglut2 were significantly reduced in the sevoflurane group.Patch-clamp recordings indicated reductions in both the frequency and amplitude of miniature excitatory postsynaptic currents(mEPSCs).Notably,davunetide significantly ameliorated the synaptic defects,social behavior deficits,and cognitive impairments induced by sevoflurane.Mechanistic analysis revealed that loss of ADNP led to dysregulation of Ca^(2+)activity via the Wnt/β-catenin signaling,resulting in decreased expression of synaptic proteins.Suppression of Wnt signaling was restored in the davunetide-treated group.Thus,ADNP was identified as a promising therapeutic target for the prevention and treatment of neurodevelopmental toxicity caused by general anesthetics.This study provides important insights into the mechanisms underlying social and cognitive disturbances caused by sevoflurane exposure in neonatal mice and elucidates the regulatory pathways involved.展开更多
During the Sui and Tang dynasties,Buddhism and Zen poetry underwent great development.Zen poetry is diverse in form,strong in personality,and high in achievement.Among the types of Zen poetry are poems,lyrics,and pros...During the Sui and Tang dynasties,Buddhism and Zen poetry underwent great development.Zen poetry is diverse in form,strong in personality,and high in achievement.Among the types of Zen poetry are poems,lyrics,and prose,some of which have social attributes closely related to the development of Chinese Buddhism.An analysis reveals that the viewpoints and information conveyed in these poems,lyrics,and prose are positively correlated with the attitudes of the emperors towards Buddhism.When the attitude of the emperor towards Buddhism reached its peak of positivity during the Tang dynasty,there was a change towards a negative correlation with the viewpoints expressed in poetry.展开更多
Gender and genetic strain are two prominent variants that influence drug abuse. Although certain sexrelated behavioral responses have been previously characterized in ICR mice, little is known about the effects of sex...Gender and genetic strain are two prominent variants that influence drug abuse. Although certain sexrelated behavioral responses have been previously characterized in ICR mice, little is known about the effects of sex on morphine-induced behavioral responses in this outbred strain. Therefore, in this study, we investigated the sex differences of morphine-induced locomotion, anxiety-like and social behaviors in ICR mice. After morphine or saline exposure for four consecutive days（twice daily）, increased locomotion, more time spent in the central area, as well as attenuated rearing and self-grooming behaviors were found in morphine-treated females in an open field; no differences were found in locomotion and the time spent in the central area between male and female controls. When interacting with the samesex individuals, female controls were engaged in more social investigation, following, body contacting and self-grooming behaviors than controls; morphine exposure reduced contacting and self-grooming behaviors in females; in contrast, these effects were not found in males. These results indicate that female ICR mice are more prosocial and are more susceptible to morphine exposure than males.展开更多
C57BL/6J and BALB/cJ mice display significant differences in sociability and response to drugs, but the phenotypic variability of their susceptibility to cocaine is still not well known. In this study, the differences...C57BL/6J and BALB/cJ mice display significant differences in sociability and response to drugs, but the phenotypic variability of their susceptibility to cocaine is still not well known. In this study, the differences between these two mice strains in the persistence of cocaine-induced conditioned place preference （CPP）, as well as the locomotion and social behaviors after the 24-hour withdrawal from a four-day cocaine （20 mg/kg/day） administration were investigated. The results showed that the cocaine-induced CPP persisted over two weeks in C57BL/6J mice, while it diminished within one week among BALB/cJ mice. After 24-hours of cocaine withdrawal, high levels of locomotion as well as low levels of social interaction and aggressive behavior were found in C57BL/6J mice, but no significant changes were found in BALB/cJ mice, indicating that cocaine-induced CPP persistence, locomotion and social behavior are not consistent between these two strains, and that overall C57BL/6J mice are more susceptible to cocaine than BALB/cJ mice at the tested doses.展开更多
Adult male tree shrews vigorously defend against intruding male conspecifics. However, the characteristics of social behavior have not been entirely explored in these males. In this study, male wild-type tree shrews(T...Adult male tree shrews vigorously defend against intruding male conspecifics. However, the characteristics of social behavior have not been entirely explored in these males. In this study, male wild-type tree shrews(Tupaia belangeri chinensis)and C57 BL/6 J mice were first allowed to familiarize themselves with an open-field apparatus. The tree shrews exhibited a short duration of movement(moving) in the novel environment, whereas the mice exhibited a long duration of movement. In the 30 min social preference-avoidance test, target animals significantly decreased the time spent by the experimental tree shrews in the social interaction(SI)zone, whereas experimental male mice exhibited the opposite. In addition, experimental tree shrews displayed a significantly longer latency to enter the SI zone in the second 15 min session(targetpresent) than in the first 15 min session(targetabsent), which was different from that found in mice.Distinct behavioral patterns in response to a conspecific male were also observed in male tree shrews and mice in the first, second, and third 5 min periods. Thus, social behaviors in tree shrews and mice appeared to be time dependent. In summary,our study provides results of a modified social preference-avoidance test designed for the assessment of social behavior in tree shrews. Our findings demonstrate the existence of social avoidance behavior in male tree shrews and prosocial behavior in male mice toward unfamiliar conspecifics. The tree shrew may be a new animal model, which differs from mice, for the study of social avoidance and prosocial behaviors.展开更多
Stress from dominance ranks in human societies, or that of other social animals, especially nonhuman primates, can have negative influences on health. Individuals holding different social status may be burdened with v...Stress from dominance ranks in human societies, or that of other social animals, especially nonhuman primates, can have negative influences on health. Individuals holding different social status may be burdened with various stress levels. The middle class experiences a special stress situation within the dominance hierarchy due to its position between the higher and lower classes. Behaviorally, questions about where middle-class stress comes from and how individuals adapt to middle-class stress remain poorly understood in nonhuman primates. In the present study, social interactions, including aggression, avoidance, grooming and mounting behaviors, between beta males, as well as among group members holding higher or lower social status, were analyzed in captive male-only cynomolgus monkey groups. We found that aggressive tension from the higher hierarchy members was the main origin of stress for middle- class individuals. However, behaviors such as attacking lower hierarchy members immediately after being the recipient of aggression, as well as increased avoidance, grooming and mounting toward both higher and lower hierarchy members helped alleviate middle-class stress and were particular adaptations to middle-class social status.展开更多
The spring home range and social behavior of Hazel grouse, (Bonasa bonasia) were studied at Changbai Mountain using radiotelemetry in 1993–94. Flock dissolution and pair formation started in mid-March. Paired males h...The spring home range and social behavior of Hazel grouse, (Bonasa bonasia) were studied at Changbai Mountain using radiotelemetry in 1993–94. Flock dissolution and pair formation started in mid-March. Paired males held territories in spring, the area was from 3.2 hm2 to 17.3 hm2 (n=2). Hazel grouse was proved to be monogamous by radiotelemetry work. The overlap of home range between paired No.10 and No.8 was 82.4%. The time of birds being together was 83.0% of the time during the prelaying period (n=53), showing that the pair bond was stable. Unpaired males showed different behavior, held a territory or wandering, and they changed their behavior in early May. The study suggested that unpaired males gave up their reproduction goal, and the acquisition for survival became more important in early May, when female started incubation.展开更多
The present review provides a compilation of the published data on the ecology and social behavior of tamarisk gerbils. Both field studies anddirect observations under semi-natural conditions provide evidence that the...The present review provides a compilation of the published data on the ecology and social behavior of tamarisk gerbils. Both field studies anddirect observations under semi-natural conditions provide evidence that the tamarisk gerbil is a nocturnal herbivorous rodent that lives in highlyseasonal habitats and displays seasonal fluctuations in reproduction and spatial organization. A typical feature of the tamarisk gerbils’ spatialorganization is higher mobility of males during the breeding season (as compared with the nonbreeding period) and formation of temporaryaggregations of males competing for access to receptive females;the composition of these aggregations was variable and depended on thereproductive condition of the females. Females tend to occupy exclusive home ranges irrespective of their reproductive condition. The matingsystem of the species can be defined as scramble competition polygyny with some features of polygynandry and promiscuity. The tamariskgerbil has distinct features of a solitary species and its social structure is primarily based on aggressive interactions or mutual avoidance ofconspecifics resulting in a dominance hierarchy among males and site-dependent dominance among females during the breeding season. Bythe end of the breeding season, males become less mobile and occupy nearly exclusive home ranges, consistent with solitary living. The mainfeatures of the spatial and social organization of this species, which distinguish it from other solitary rodents, are the higher mobility of malesand the formation of temporary multimale–multifemale aggregations during the breeding season. Overall, the data presented expand our understanding of socioecology of gerbils.展开更多
Synapse organizers are essential for the development,transmission,and plasticity of synapses.Acting as rare synapse suppressors,the MAM domain containing glycosylphosphatidylinositol anchor(MDGA)proteins contributes t...Synapse organizers are essential for the development,transmission,and plasticity of synapses.Acting as rare synapse suppressors,the MAM domain containing glycosylphosphatidylinositol anchor(MDGA)proteins contributes to synapse organization by inhibiting the formation of the synaptogenic neuroligin-neurexin complex.A previous analysis of MDGA2 mice lacking a single copy of Mdga2 revealed upregulated glutamatergic synapses and behaviors consistent with autism.However,MDGA2 is expressed in diverse cell types and is localized to both excitatory and inhibitory synapses.Differentiating the network versus cell-specific effects of MDGA2 loss-of-function requires a cell-type and brain region-selective strategy.To address this,we generated mice harboring a conditional knockout of Mdga2 restricted to CA1 pyramidal neurons.Here we report that MDGA2 suppresses the density and function of excitatory synapses selectively on pyramidal neurons in the mature hippocampus.Conditional deletion of Mdga2 in CA1 pyramidal neurons of adult mice upregulated miniature and spontaneous excitatory postsynaptic potentials,vesicular glutamate transporter 1 intensity,and neuronal excitability.These effects were limited to glutamatergic synapses as no changes were detected in miniature and spontaneous inhibitory postsynaptic potential properties or vesicular GABA transporter intensity.Functionally,evoked basal synaptic transmission and AMPAR receptor currents were enhanced at glutamatergic inputs.At a behavioral level,memory appeared to be compromised in Mdga2 cKO mice as both novel object recognition and contextual fear conditioning performance were impaired,consistent with deficits in long-term potentiation in the CA3-CA1 pathway.Social affiliation,a behavioral analog of social deficits in autism,was similarly compromised.These results demonstrate that MDGA2 confines the properties of excitatory synapses to CA1 neurons in mature hippocampal circuits,thereby optimizing this network for plasticity,cognition,and social behaviors.展开更多
Background: The use of social media platforms for health and nutrition information has become popular among college students. Although social media made information readily accessible in different formats, nutritional...Background: The use of social media platforms for health and nutrition information has become popular among college students. Although social media made information readily accessible in different formats, nutritional misinformation promoted by influencers and non-experts caused negative impact on diet behavior and perception of body image. Previous research indicated that extensive use of social media was positively linked to disordered eating behaviors. Social media platforms like Facebook and Instagram that allow users to follow celebrities intensified exposure to influencers’ messages and images and resulted in negative moods and body dissatisfaction. Objective: This paper aims to explore the impact of social media on college students’ dietary behaviors and body image. Participants: 18 undergraduate students from a public university in the Southern United States were recruited through a mass email. Methods: A cross-sectional qualitative study of three focus groups was conducted. The focus groups were based on guiding open-ended questions. Atlas.ti was used to code and analyze the data using inductive and deductive codes. Results: Three main themes were identified. The conditions theme included elements that explain why and how social media influences the participants’ actions. The actions theme included eating behavior, physical activity, and dietary supplement intake. The consequences theme describes anticipated or actual outcomes of actions such as body image and ideal weight. Conclusions: Social media has had a negative influence on diet behaviors and a positive influence on physical activity. Evidence-based nutrition and weight management information is needed to thwart potential misinformation.展开更多
This study investigated the efects of boarding at school on students'prosocial behaviors in rural China using data from the National Children's Study of China.The instrumental variable(IV)approach was used to ...This study investigated the efects of boarding at school on students'prosocial behaviors in rural China using data from the National Children's Study of China.The instrumental variable(IV)approach was used to control for potential endogeneity,and the IVs were the proportion of boarding students in higher grades and the school area per student.The ordinary least squares and IV estimates showed that boarding students exhibited more prosocial behaviors,including compliance with rules,positive traits,and altruistic attitudes.These results were robust.Heterogeneity analyses suggested that students from low-income families,children who were not"left behind,"high-grade students,and female students were more likely to benefit from boarding.We found that these effects were primarily due to boarding students developing stronger feelings of trust and support from their peers and teachers and participating in more school-organized events and team activities.展开更多
As social media and online activity continue to pervade all age groups, it serves as a crucial platform for sharing personal experiences and opinions as well as information about attitudes and preferences for certain ...As social media and online activity continue to pervade all age groups, it serves as a crucial platform for sharing personal experiences and opinions as well as information about attitudes and preferences for certain interests or purchases. This generates a wealth of behavioral data, which, while invaluable to businesses, researchers, policymakers, and the cybersecurity sector, presents significant challenges due to its unstructured nature. Existing tools for analyzing this data often lack the capability to effectively retrieve and process it comprehensively. This paper addresses the need for an advanced analytical tool that ethically and legally collects and analyzes social media data and online activity logs, constructing detailed and structured user profiles. It reviews current solutions, highlights their limitations, and introduces a new approach, the Advanced Social Analyzer (ASAN), that bridges these gaps. The proposed solutions technical aspects, implementation, and evaluation are discussed, with results compared to existing methodologies. The paper concludes by suggesting future research directions to further enhance the utility and effectiveness of social media data analysis.展开更多
Fertility control has been identified by studies in the laboratory and the field as a more appropriate and long-term control strategy for rodent pests than lethal control.In this study,we investigated the effects of q...Fertility control has been identified by studies in the laboratory and the field as a more appropriate and long-term control strategy for rodent pests than lethal control.In this study,we investigated the effects of quinestrol on mass of reproductive organs and on social behaviors in female and male Himalayan field rats(Rattus nitidus).A total of 16 adult females and 16 adult males were randomly assigned to 4 groups.One male and one female group were fed rice with 0.005%quinestrol by weight for 7 days,and another 2 groups were fed rice only.After 7 days,rats were assigned to 10 min dyadic encounters between groups,and investigation,aggression,defense and attack latency were quantified.All animals were killed on day 10,and reproductive organs were dissected and weighed.Dyadic encounter data showed that there were obvious changes in social behaviors of quinestrol-treated rats.Quinestrol significantly inhibited the investigative behavior of quinestrol-treated males toward control females in Rattus nitidus,but seldom affected investigation between control males and quinestrol-treated females.Aggression of control females toward quinestrol-treated males was higher than that of quinestrol-treated females,and defense of quinestrol-treated males toward control females was more remarkable than that of control males.Quinestrol remarkably decreased wet masses of epididymis and spermotophore in males and ovaries in females,but had no effect on wet masses of testes and uteri after quinestrol treatment.These results indicate that the anti-fertility effects of quinestrol on R.nitidus are attributed to not only suppressing reproductive organs but also impacting social behaviors associated with territory defense and mate choice.展开更多
Rapid advances in Ribonucleic Acid sequencing(or RNA-seq)technology for analyzing entire transcriptomes of desired tissue samples,or even of single cells at scale,have revolutionized biology in the past decade.Increas...Rapid advances in Ribonucleic Acid sequencing(or RNA-seq)technology for analyzing entire transcriptomes of desired tissue samples,or even of single cells at scale,have revolutionized biology in the past decade.Increasing accessibility and falling costs are making it possible to address many problems in biology that were once considered intractable,including the study of various social behaviors.RNA-seq is opening new avenues to understand long-standing questions on the molecular basis of behavioral plasticity and individual variation in the expression of a behavior.As whole transcriptomes are examined,it has become possible to make unbiased discoveries of underlying mechanisms with little or no necessity to predict genes involved in advance.However,researchers need to be aware of technical limitations and have to make specific decisions when applying RNA-seq to study social behavior.Here,we provide a perspective on the applications of RNA-seq and experimental design considerations for behavioral scientists who are unfamiliar with the technology but are considering using it in their research.展开更多
This study is based on the emergence of teenagers1 behaviors which is deviated from the tradition of Minangkabau society.It aims to determine how hedonism affects Minangkabau's local pearls of wisdom.A qualitative...This study is based on the emergence of teenagers1 behaviors which is deviated from the tradition of Minangkabau society.It aims to determine how hedonism affects Minangkabau's local pearls of wisdom.A qualitative approach with phenomenology research design was used where 25 Minangkabau teenagers,religious and traditional leaders who live in Lima Puluh Kota,Tanah Datar,and Agam involved in the study.The data taken from observation,interview,and documentation.The results reveal that the paradigm shift of young Minangkabau's social behavior is caused by hedonism that can be seen in both positive and negative aspects.In positive ways,they live their lives mainly to fulfill their needs,add experiences,create a sense of secure for the community,and be open minded.Meanwhile,in negative ways,traditions based on Islamic laws and the Holly Quran were regarded only as symbols.Such hedonism tends to trigger crime,individualism,laziness,free-sex,insecurity,and consumptive.Thus,this kind of behavior was caused by the absence of religious and custom education they had in the family and social lives.展开更多
Many extant species spin cocoons before their pupal stage,which can protect them from predators,pathogens,and fluctuant environmental factors in nests.However,owing to the scarcity of ant cocoon fossils,little is know...Many extant species spin cocoons before their pupal stage,which can protect them from predators,pathogens,and fluctuant environmental factors in nests.However,owing to the scarcity of ant cocoon fossils,little is known about the origin and evolution of this behavior in Formicidae.Here,we describe two ant pupae specimens from Myanmar amber.The presence of cocoons in these Mesozoic fossils suggests the ancestral origin of spinning cocoon behavior;based on our phylogenetic analysis and ancestral state reconstruction,this behavior was secondarily lost at least six times in Formicidae,which could be ascribed to the transition of nesting and feeding habits,as well as the development of eusociality.Moreover,the first specimen preserved worker ants with empty cocoons simultaneously,indicating garbage removal or brood care behavior,which improves our understanding of their eusociality in the Cretaceous.展开更多
Taking Nanjing as a case, the paper explains the spatial behavior differences existing in the information technology use among different groups of residents and households, by virtue of analyzing the survey data of ur...Taking Nanjing as a case, the paper explains the spatial behavior differences existing in the information technology use among different groups of residents and households, by virtue of analyzing the survey data of urban households in the 11 districts of Nanjing, from the social, spatial, life and other non-technical angles. Also it makes various analyses and evaluation quantitatively and qualitatively on the social and spatial effect of information technology. The results show that the new technology is changing the social spatial behaviors of urban residents. New behavioral spaces of urban family such as telecommuting, email and QQ have begun to emerge. With the help of Internet, the communication scope of families has expanded greatly, and more new forms of publicizing community information have begun to emerge. Telecommunication contact forms have been developing swiftly, and their frequencies of contact have been increasing dramatically.展开更多
The e-mail network is a type of social network. This study analyzes user behavior in e-mail subject participation in organizations by using social network analysis. First, the Enron dataset and the position-related in...The e-mail network is a type of social network. This study analyzes user behavior in e-mail subject participation in organizations by using social network analysis. First, the Enron dataset and the position-related information of an employee are introduced, and methods for deletion of false data are presented. Next, the three-layer model(User, Subject, Keyword) is proposed for analysis of user behavior. Then, the proposed keyword selection algorithm based on a greedy approach, and the influence and propagation of an e-mail subject are defined. Finally, the e-mail user behavior is analyzed for the Enron organization. This study has considerable significance in subject recommendation and character recognition.展开更多
Purpose:The aim of the present study was to analyze the associations of youths' sedentary behavior(SB) with parents' and siblings' SB and physical activity(PA),as well as the associations of youths' co...Purpose:The aim of the present study was to analyze the associations of youths' sedentary behavior(SB) with parents' and siblings' SB and physical activity(PA),as well as the associations of youths' coparticipation with parents,siblings,and friends in PA and SB with youths' SB.Methods:The sample consisted of 1543 youths(12.02±2.51 years;788 boys) enrolled in the baseline cohort of the UP&DOWN study.SB was assessed by accelerometry and questionnaire.Participants reported the time spent by their parents and siblings watching television,playing videogames,surfing the Internet,sitting/resting,and doing PA.Further,participants reported coparticipation with parents,siblings,and friends in these activities.Linear mixed models,including school and city as random effects,were performed.Results:Parents' television time was positively associated with youths' screen-based SB.Coparticipation with friends in playing videogames(in boys) and in surfing the Internet(in girls) showed a positive association with screen-based SB and a negative association with educational-based SB.Moreover,coparticipation with siblings and friends in PA was inversely associated with accelerometer-based SB in boys and girls.Conclusion:Our results emphasize the important role of social modeling in the development of sedentary lifestyles in youths.Interventions aimed at reducing health risk behaviors in youths could be more effective if they are oriented from a social perspective that involves their families and networks of their closest friends.展开更多
Stress studies frequently utilize physical stressors to establish animal models of stress. In the majority of cases, these models are not consistent with human circumstances. The present study simulated a social isola...Stress studies frequently utilize physical stressors to establish animal models of stress. In the majority of cases, these models are not consistent with human circumstances. The present study simulated a social isolation plus resident intruder stress model in the rat. The rats were subjected to daily social isolation and resident intruder stress for 2 weeks. Behaviors were then tested. Rats subjected to social stress exhibited different aggressive behavior styles; some rats had greater scores on composite aggression behaviors, as well as locomotor and exploratory activity, but lower scores on latency than others. The high-aggressive group exhibited predominantly anger-out, while the low-aggressive group exhibited anger-in. Results suggest that social isolation plus resident intruder may serve as an appropriate model for anger-in and anger-out emotion modeling in the rat.展开更多
基金supported by the National Natural Science Foundation of China(82171170,81971076,82371277 to H.Z.,82101345 to L.R.L.)。
文摘A growing number of studies have demonstrated that repeated exposure to sevoflurane during development results in persistent social abnormalities and cognitive impairment.Davunetide,an active fragment of the activity-dependent neuroprotective protein(ADNP),has been implicated in social and cognitive protection.However,the potential of davunetide to attenuate social deficits following sevoflurane exposure and the underlying developmental mechanisms remain poorly understood.In this study,ribosome and proteome profiles were analyzed to investigate the molecular basis of sevoflurane-induced social deficits in neonatal mice.The neuropathological basis was also explored using Golgi staining,morphological analysis,western blotting,electrophysiological analysis,and behavioral analysis.Results indicated that ADNP was significantly down-regulated following developmental exposure to sevoflurane.In adulthood,anterior cingulate cortex(ACC)neurons exposed to sevoflurane exhibited a decrease in dendrite number,total dendrite length,and spine density.Furthermore,the expression levels of Homer,PSD95,synaptophysin,and vglut2 were significantly reduced in the sevoflurane group.Patch-clamp recordings indicated reductions in both the frequency and amplitude of miniature excitatory postsynaptic currents(mEPSCs).Notably,davunetide significantly ameliorated the synaptic defects,social behavior deficits,and cognitive impairments induced by sevoflurane.Mechanistic analysis revealed that loss of ADNP led to dysregulation of Ca^(2+)activity via the Wnt/β-catenin signaling,resulting in decreased expression of synaptic proteins.Suppression of Wnt signaling was restored in the davunetide-treated group.Thus,ADNP was identified as a promising therapeutic target for the prevention and treatment of neurodevelopmental toxicity caused by general anesthetics.This study provides important insights into the mechanisms underlying social and cognitive disturbances caused by sevoflurane exposure in neonatal mice and elucidates the regulatory pathways involved.
基金北京市大学生创新训练项目-中国传统诗词文化中的“社交行为”研究,Serial NumberS202210015035北京大学生创新训练项目-大学生传统文化习得中的实践逻辑研究,Serial Number S200210015037北京市大学生创新训练项目-先秦子部“寓言”文本生成与传播路径研究,Serial Number S202210015036.
文摘During the Sui and Tang dynasties,Buddhism and Zen poetry underwent great development.Zen poetry is diverse in form,strong in personality,and high in achievement.Among the types of Zen poetry are poems,lyrics,and prose,some of which have social attributes closely related to the development of Chinese Buddhism.An analysis reveals that the viewpoints and information conveyed in these poems,lyrics,and prose are positively correlated with the attitudes of the emperors towards Buddhism.When the attitude of the emperor towards Buddhism reached its peak of positivity during the Tang dynasty,there was a change towards a negative correlation with the viewpoints expressed in poetry.
基金supported by the National Natural Science Foundation of China(31260513)the National Innovation Experiment Program for University Students(XJCX-2014-106)
文摘Gender and genetic strain are two prominent variants that influence drug abuse. Although certain sexrelated behavioral responses have been previously characterized in ICR mice, little is known about the effects of sex on morphine-induced behavioral responses in this outbred strain. Therefore, in this study, we investigated the sex differences of morphine-induced locomotion, anxiety-like and social behaviors in ICR mice. After morphine or saline exposure for four consecutive days（twice daily）, increased locomotion, more time spent in the central area, as well as attenuated rearing and self-grooming behaviors were found in morphine-treated females in an open field; no differences were found in locomotion and the time spent in the central area between male and female controls. When interacting with the samesex individuals, female controls were engaged in more social investigation, following, body contacting and self-grooming behaviors than controls; morphine exposure reduced contacting and self-grooming behaviors in females; in contrast, these effects were not found in males. These results indicate that female ICR mice are more prosocial and are more susceptible to morphine exposure than males.
基金Foundation items： This research was supported by the National Nat- ural Science Foundation of China （31260513）, the National Natural Science Foundation of Ningxia （NZ14077） and the Science Foundation of Beifang University of Nationalities （2012Y052）
文摘C57BL/6J and BALB/cJ mice display significant differences in sociability and response to drugs, but the phenotypic variability of their susceptibility to cocaine is still not well known. In this study, the differences between these two mice strains in the persistence of cocaine-induced conditioned place preference （CPP）, as well as the locomotion and social behaviors after the 24-hour withdrawal from a four-day cocaine （20 mg/kg/day） administration were investigated. The results showed that the cocaine-induced CPP persisted over two weeks in C57BL/6J mice, while it diminished within one week among BALB/cJ mice. After 24-hours of cocaine withdrawal, high levels of locomotion as well as low levels of social interaction and aggressive behavior were found in C57BL/6J mice, but no significant changes were found in BALB/cJ mice, indicating that cocaine-induced CPP persistence, locomotion and social behavior are not consistent between these two strains, and that overall C57BL/6J mice are more susceptible to cocaine than BALB/cJ mice at the tested doses.
基金the National Natural Science Foundation of China(81671344,31500859)Major International(Regional)Joint Research Project of the National Natural Science Foundation of China(81920108018)+1 种基金1.3.5 Project for Disciplines of Excellence,Special Foundation for Brain Research from the Science and Technology Program of Guangdong(2018B030334001)West China Hospital of Sichuan University(ZY2016103,ZY2016203)。
文摘Adult male tree shrews vigorously defend against intruding male conspecifics. However, the characteristics of social behavior have not been entirely explored in these males. In this study, male wild-type tree shrews(Tupaia belangeri chinensis)and C57 BL/6 J mice were first allowed to familiarize themselves with an open-field apparatus. The tree shrews exhibited a short duration of movement(moving) in the novel environment, whereas the mice exhibited a long duration of movement. In the 30 min social preference-avoidance test, target animals significantly decreased the time spent by the experimental tree shrews in the social interaction(SI)zone, whereas experimental male mice exhibited the opposite. In addition, experimental tree shrews displayed a significantly longer latency to enter the SI zone in the second 15 min session(targetpresent) than in the first 15 min session(targetabsent), which was different from that found in mice.Distinct behavioral patterns in response to a conspecific male were also observed in male tree shrews and mice in the first, second, and third 5 min periods. Thus, social behaviors in tree shrews and mice appeared to be time dependent. In summary,our study provides results of a modified social preference-avoidance test designed for the assessment of social behavior in tree shrews. Our findings demonstrate the existence of social avoidance behavior in male tree shrews and prosocial behavior in male mice toward unfamiliar conspecifics. The tree shrew may be a new animal model, which differs from mice, for the study of social avoidance and prosocial behaviors.
基金Foundation items： This study was supported by the Ministry of Science and Technology of China Grant （2012CB825500） and the Youth Innovation Promotion Association of Chinese Academy of Sciences （2012075）
文摘Stress from dominance ranks in human societies, or that of other social animals, especially nonhuman primates, can have negative influences on health. Individuals holding different social status may be burdened with various stress levels. The middle class experiences a special stress situation within the dominance hierarchy due to its position between the higher and lower classes. Behaviorally, questions about where middle-class stress comes from and how individuals adapt to middle-class stress remain poorly understood in nonhuman primates. In the present study, social interactions, including aggression, avoidance, grooming and mounting behaviors, between beta males, as well as among group members holding higher or lower social status, were analyzed in captive male-only cynomolgus monkey groups. We found that aggressive tension from the higher hierarchy members was the main origin of stress for middle- class individuals. However, behaviors such as attacking lower hierarchy members immediately after being the recipient of aggression, as well as increased avoidance, grooming and mounting toward both higher and lower hierarchy members helped alleviate middle-class stress and were particular adaptations to middle-class social status.
文摘The spring home range and social behavior of Hazel grouse, (Bonasa bonasia) were studied at Changbai Mountain using radiotelemetry in 1993–94. Flock dissolution and pair formation started in mid-March. Paired males held territories in spring, the area was from 3.2 hm2 to 17.3 hm2 (n=2). Hazel grouse was proved to be monogamous by radiotelemetry work. The overlap of home range between paired No.10 and No.8 was 82.4%. The time of birds being together was 83.0% of the time during the prelaying period (n=53), showing that the pair bond was stable. Unpaired males showed different behavior, held a territory or wandering, and they changed their behavior in early May. The study suggested that unpaired males gave up their reproduction goal, and the acquisition for survival became more important in early May, when female started incubation.
文摘The present review provides a compilation of the published data on the ecology and social behavior of tamarisk gerbils. Both field studies anddirect observations under semi-natural conditions provide evidence that the tamarisk gerbil is a nocturnal herbivorous rodent that lives in highlyseasonal habitats and displays seasonal fluctuations in reproduction and spatial organization. A typical feature of the tamarisk gerbils’ spatialorganization is higher mobility of males during the breeding season (as compared with the nonbreeding period) and formation of temporaryaggregations of males competing for access to receptive females;the composition of these aggregations was variable and depended on thereproductive condition of the females. Females tend to occupy exclusive home ranges irrespective of their reproductive condition. The matingsystem of the species can be defined as scramble competition polygyny with some features of polygynandry and promiscuity. The tamariskgerbil has distinct features of a solitary species and its social structure is primarily based on aggressive interactions or mutual avoidance ofconspecifics resulting in a dominance hierarchy among males and site-dependent dominance among females during the breeding season. Bythe end of the breeding season, males become less mobile and occupy nearly exclusive home ranges, consistent with solitary living. The mainfeatures of the spatial and social organization of this species, which distinguish it from other solitary rodents, are the higher mobility of malesand the formation of temporary multimale–multifemale aggregations during the breeding season. Overall, the data presented expand our understanding of socioecology of gerbils.
基金supported by the National Natural Science Foundation of China(82001203,82173819,81871012,and 81571263)the Scientific Research Fund of Zhejiang Provincial Education Department(Y201839276)+3 种基金the Scientific Research Foundation of Zhejiang University City College(X-202103)the R&D Project of Zhejiang(2022C03034)the Natural Science Foundation of Zhejiang Province(LQ23C090001)a Canada Research Chair Award(P2018-0246).
文摘Synapse organizers are essential for the development,transmission,and plasticity of synapses.Acting as rare synapse suppressors,the MAM domain containing glycosylphosphatidylinositol anchor(MDGA)proteins contributes to synapse organization by inhibiting the formation of the synaptogenic neuroligin-neurexin complex.A previous analysis of MDGA2 mice lacking a single copy of Mdga2 revealed upregulated glutamatergic synapses and behaviors consistent with autism.However,MDGA2 is expressed in diverse cell types and is localized to both excitatory and inhibitory synapses.Differentiating the network versus cell-specific effects of MDGA2 loss-of-function requires a cell-type and brain region-selective strategy.To address this,we generated mice harboring a conditional knockout of Mdga2 restricted to CA1 pyramidal neurons.Here we report that MDGA2 suppresses the density and function of excitatory synapses selectively on pyramidal neurons in the mature hippocampus.Conditional deletion of Mdga2 in CA1 pyramidal neurons of adult mice upregulated miniature and spontaneous excitatory postsynaptic potentials,vesicular glutamate transporter 1 intensity,and neuronal excitability.These effects were limited to glutamatergic synapses as no changes were detected in miniature and spontaneous inhibitory postsynaptic potential properties or vesicular GABA transporter intensity.Functionally,evoked basal synaptic transmission and AMPAR receptor currents were enhanced at glutamatergic inputs.At a behavioral level,memory appeared to be compromised in Mdga2 cKO mice as both novel object recognition and contextual fear conditioning performance were impaired,consistent with deficits in long-term potentiation in the CA3-CA1 pathway.Social affiliation,a behavioral analog of social deficits in autism,was similarly compromised.These results demonstrate that MDGA2 confines the properties of excitatory synapses to CA1 neurons in mature hippocampal circuits,thereby optimizing this network for plasticity,cognition,and social behaviors.
文摘Background: The use of social media platforms for health and nutrition information has become popular among college students. Although social media made information readily accessible in different formats, nutritional misinformation promoted by influencers and non-experts caused negative impact on diet behavior and perception of body image. Previous research indicated that extensive use of social media was positively linked to disordered eating behaviors. Social media platforms like Facebook and Instagram that allow users to follow celebrities intensified exposure to influencers’ messages and images and resulted in negative moods and body dissatisfaction. Objective: This paper aims to explore the impact of social media on college students’ dietary behaviors and body image. Participants: 18 undergraduate students from a public university in the Southern United States were recruited through a mass email. Methods: A cross-sectional qualitative study of three focus groups was conducted. The focus groups were based on guiding open-ended questions. Atlas.ti was used to code and analyze the data using inductive and deductive codes. Results: Three main themes were identified. The conditions theme included elements that explain why and how social media influences the participants’ actions. The actions theme included eating behavior, physical activity, and dietary supplement intake. The consequences theme describes anticipated or actual outcomes of actions such as body image and ideal weight. Conclusions: Social media has had a negative influence on diet behaviors and a positive influence on physical activity. Evidence-based nutrition and weight management information is needed to thwart potential misinformation.
基金by the Science and Technology Project of Chongqing Municipal Education Commission(Nos.KJQN202100309 and KJZD-K202200307)the Chongqing Education Science Project(No.2018-GX-006)the Southwestern University of Finance and Economics under the 111 Project Research Base(No.B16040).
文摘This study investigated the efects of boarding at school on students'prosocial behaviors in rural China using data from the National Children's Study of China.The instrumental variable(IV)approach was used to control for potential endogeneity,and the IVs were the proportion of boarding students in higher grades and the school area per student.The ordinary least squares and IV estimates showed that boarding students exhibited more prosocial behaviors,including compliance with rules,positive traits,and altruistic attitudes.These results were robust.Heterogeneity analyses suggested that students from low-income families,children who were not"left behind,"high-grade students,and female students were more likely to benefit from boarding.We found that these effects were primarily due to boarding students developing stronger feelings of trust and support from their peers and teachers and participating in more school-organized events and team activities.
文摘As social media and online activity continue to pervade all age groups, it serves as a crucial platform for sharing personal experiences and opinions as well as information about attitudes and preferences for certain interests or purchases. This generates a wealth of behavioral data, which, while invaluable to businesses, researchers, policymakers, and the cybersecurity sector, presents significant challenges due to its unstructured nature. Existing tools for analyzing this data often lack the capability to effectively retrieve and process it comprehensively. This paper addresses the need for an advanced analytical tool that ethically and legally collects and analyzes social media data and online activity logs, constructing detailed and structured user profiles. It reviews current solutions, highlights their limitations, and introduces a new approach, the Advanced Social Analyzer (ASAN), that bridges these gaps. The proposed solutions technical aspects, implementation, and evaluation are discussed, with results compared to existing methodologies. The paper concludes by suggesting future research directions to further enhance the utility and effectiveness of social media data analysis.
基金supported by National Basic Research Program of China(2007CB109105)Guangdong Provincial Public Laboratory on Wild Animal Conservation and Management(Grant No.2009002)+2 种基金Science&Technology Planning Project of Guangzhou(2008Z1-E101)Guangdong(2010B020311003,2011B090300039)Guangdong Natural Science Fund(10151026001000006).
文摘Fertility control has been identified by studies in the laboratory and the field as a more appropriate and long-term control strategy for rodent pests than lethal control.In this study,we investigated the effects of quinestrol on mass of reproductive organs and on social behaviors in female and male Himalayan field rats(Rattus nitidus).A total of 16 adult females and 16 adult males were randomly assigned to 4 groups.One male and one female group were fed rice with 0.005%quinestrol by weight for 7 days,and another 2 groups were fed rice only.After 7 days,rats were assigned to 10 min dyadic encounters between groups,and investigation,aggression,defense and attack latency were quantified.All animals were killed on day 10,and reproductive organs were dissected and weighed.Dyadic encounter data showed that there were obvious changes in social behaviors of quinestrol-treated rats.Quinestrol significantly inhibited the investigative behavior of quinestrol-treated males toward control females in Rattus nitidus,but seldom affected investigation between control males and quinestrol-treated females.Aggression of control females toward quinestrol-treated males was higher than that of quinestrol-treated females,and defense of quinestrol-treated males toward control females was more remarkable than that of control males.Quinestrol remarkably decreased wet masses of epididymis and spermotophore in males and ovaries in females,but had no effect on wet masses of testes and uteri after quinestrol treatment.These results indicate that the anti-fertility effects of quinestrol on R.nitidus are attributed to not only suppressing reproductive organs but also impacting social behaviors associated with territory defense and mate choice.
基金This work was supported by Yale-NUS College through grants R-607-265-225-121 and IG16-LR003.
文摘Rapid advances in Ribonucleic Acid sequencing(or RNA-seq)technology for analyzing entire transcriptomes of desired tissue samples,or even of single cells at scale,have revolutionized biology in the past decade.Increasing accessibility and falling costs are making it possible to address many problems in biology that were once considered intractable,including the study of various social behaviors.RNA-seq is opening new avenues to understand long-standing questions on the molecular basis of behavioral plasticity and individual variation in the expression of a behavior.As whole transcriptomes are examined,it has become possible to make unbiased discoveries of underlying mechanisms with little or no necessity to predict genes involved in advance.However,researchers need to be aware of technical limitations and have to make specific decisions when applying RNA-seq to study social behavior.Here,we provide a perspective on the applications of RNA-seq and experimental design considerations for behavioral scientists who are unfamiliar with the technology but are considering using it in their research.
文摘This study is based on the emergence of teenagers1 behaviors which is deviated from the tradition of Minangkabau society.It aims to determine how hedonism affects Minangkabau's local pearls of wisdom.A qualitative approach with phenomenology research design was used where 25 Minangkabau teenagers,religious and traditional leaders who live in Lima Puluh Kota,Tanah Datar,and Agam involved in the study.The data taken from observation,interview,and documentation.The results reveal that the paradigm shift of young Minangkabau's social behavior is caused by hedonism that can be seen in both positive and negative aspects.In positive ways,they live their lives mainly to fulfill their needs,add experiences,create a sense of secure for the community,and be open minded.Meanwhile,in negative ways,traditions based on Islamic laws and the Holly Quran were regarded only as symbols.Such hedonism tends to trigger crime,individualism,laziness,free-sex,insecurity,and consumptive.Thus,this kind of behavior was caused by the absence of religious and custom education they had in the family and social lives.
基金This study was supported by the National Natural Science Foundation of China(No.of 31830084,31970440&32070466)also supported by“the Fundamental Research Funds for the Central Universities”,Nankai University(No.96172158,96173250&91822294).
文摘Many extant species spin cocoons before their pupal stage,which can protect them from predators,pathogens,and fluctuant environmental factors in nests.However,owing to the scarcity of ant cocoon fossils,little is known about the origin and evolution of this behavior in Formicidae.Here,we describe two ant pupae specimens from Myanmar amber.The presence of cocoons in these Mesozoic fossils suggests the ancestral origin of spinning cocoon behavior;based on our phylogenetic analysis and ancestral state reconstruction,this behavior was secondarily lost at least six times in Formicidae,which could be ascribed to the transition of nesting and feeding habits,as well as the development of eusociality.Moreover,the first specimen preserved worker ants with empty cocoons simultaneously,indicating garbage removal or brood care behavior,which improves our understanding of their eusociality in the Cretaceous.
基金Under the auspices of Key Project of National Natural Science Foundation of China (No. 40435013, 40301014)
文摘Taking Nanjing as a case, the paper explains the spatial behavior differences existing in the information technology use among different groups of residents and households, by virtue of analyzing the survey data of urban households in the 11 districts of Nanjing, from the social, spatial, life and other non-technical angles. Also it makes various analyses and evaluation quantitatively and qualitatively on the social and spatial effect of information technology. The results show that the new technology is changing the social spatial behaviors of urban residents. New behavioral spaces of urban family such as telecommuting, email and QQ have begun to emerge. With the help of Internet, the communication scope of families has expanded greatly, and more new forms of publicizing community information have begun to emerge. Telecommunication contact forms have been developing swiftly, and their frequencies of contact have been increasing dramatically.
基金sponsored by the National Natural Science Foundation of China under grant number No.61100008,61201084the China Postdoctoral Science Foundation under Grant No.2013M541346+3 种基金Heilongiiang Postdoctoral Special Fund(Postdoctoral Youth Talent Program)under Grant No.LBH-TZ0504Heilongjiang Postdoctoral Fund under Grant No.LBH-Z13058the Natural Science Foundation of Heilongjiang Province of China under Grant No.QC2015076The Fundamental Research Funds for the Central Universities of China under grant number HEUCF100602
文摘The e-mail network is a type of social network. This study analyzes user behavior in e-mail subject participation in organizations by using social network analysis. First, the Enron dataset and the position-related information of an employee are introduced, and methods for deletion of false data are presented. Next, the three-layer model(User, Subject, Keyword) is proposed for analysis of user behavior. Then, the proposed keyword selection algorithm based on a greedy approach, and the influence and propagation of an e-mail subject are defined. Finally, the e-mail user behavior is analyzed for the Enron organization. This study has considerable significance in subject recommendation and character recognition.
基金supported by a DEP 2010-21662-C04-00 grant from the National Plan for Research,Development and Innovation(R+D+i)of the Spanish Ministry(MICINN)supported by pre-doctoral grants(FPI)from the Autonomous University of Madrid。
文摘Purpose:The aim of the present study was to analyze the associations of youths' sedentary behavior(SB) with parents' and siblings' SB and physical activity(PA),as well as the associations of youths' coparticipation with parents,siblings,and friends in PA and SB with youths' SB.Methods:The sample consisted of 1543 youths(12.02±2.51 years;788 boys) enrolled in the baseline cohort of the UP&DOWN study.SB was assessed by accelerometry and questionnaire.Participants reported the time spent by their parents and siblings watching television,playing videogames,surfing the Internet,sitting/resting,and doing PA.Further,participants reported coparticipation with parents,siblings,and friends in these activities.Linear mixed models,including school and city as random effects,were performed.Results:Parents' television time was positively associated with youths' screen-based SB.Coparticipation with friends in playing videogames(in boys) and in surfing the Internet(in girls) showed a positive association with screen-based SB and a negative association with educational-based SB.Moreover,coparticipation with siblings and friends in PA was inversely associated with accelerometer-based SB in boys and girls.Conclusion:Our results emphasize the important role of social modeling in the development of sedentary lifestyles in youths.Interventions aimed at reducing health risk behaviors in youths could be more effective if they are oriented from a social perspective that involves their families and networks of their closest friends.
基金the National Natural Science Foundation of China,No.30973688the National Program of Key Basic Research Project(973Program),No.2006CB504804
文摘Stress studies frequently utilize physical stressors to establish animal models of stress. In the majority of cases, these models are not consistent with human circumstances. The present study simulated a social isolation plus resident intruder stress model in the rat. The rats were subjected to daily social isolation and resident intruder stress for 2 weeks. Behaviors were then tested. Rats subjected to social stress exhibited different aggressive behavior styles; some rats had greater scores on composite aggression behaviors, as well as locomotor and exploratory activity, but lower scores on latency than others. The high-aggressive group exhibited predominantly anger-out, while the low-aggressive group exhibited anger-in. Results suggest that social isolation plus resident intruder may serve as an appropriate model for anger-in and anger-out emotion modeling in the rat.
