AIM：To quantitatively assess narrow anterior chamber angle using spectral-domain anterior segment optical coherence tomography（SD-AS-OCT） and ultrasound biomicroscopy（UBM）,and to evaluate the correlations and con...AIM：To quantitatively assess narrow anterior chamber angle using spectral-domain anterior segment optical coherence tomography（SD-AS-OCT） and ultrasound biomicroscopy（UBM）,and to evaluate the correlations and consistency between SD-AS-OCT and UBM.· METHODS：Fifty-five eyes from 40 patients were examined.Patients were diagnosed with primary angleclosure glaucoma（PACG） remission（11 eyes from 8patients）,primary angle closure（PAC,20 eyes from 20patients） and PAC suspect（24 eyes from 12 patients）.Each eye was examined by SD-AS-OCT and UBM after laser peripheral iridotomy（LPI）.The measurements of SD-AS-OCT were angle open distance（AOD）,anterior chamber angle（ACA）,trabecular iris angle（TIA）,and trabecular iris space area（TISA）.UBM measurements were AOD and TIA.Correlations of AOD500 and TIA500 between UBM and AS-OCT were assessed.All parameters were analysed by SPSS 16.0 and MedCalc.· RESULTS：ACA,TIA and AOD measured by SD-ASOCT reached a maximum at the temporal quadrant and minimum at the nasal quadrant.Group parameters of AOD500 and AOD750 showed a linear positive correlation,and AOD750 had less variability.UBM outcomes of AOD500 and TIA500 were significantly smaller than those of SD-AS-OCT.The results of the two techniques were correlated at the superior,nasal and inferior quadrants.CONCLUSION：Both UBM and SD-AS-OCT are efficient tools for follow-up during the course of PACG.We recommended using parameters at 750 μm anterior to the sclera spur for the screening and follow-up of PACG and PAC.The two methods might be alternatives to each other.展开更多
The similarity measure is crucial to the performance of spectral clustering. The Gaussian kernel function based on the Euclidean distance is usual y adopted as the similarity measure. However, the Euclidean distance m...The similarity measure is crucial to the performance of spectral clustering. The Gaussian kernel function based on the Euclidean distance is usual y adopted as the similarity measure. However, the Euclidean distance measure cannot ful y reveal the complex distribution data, and the result of spectral clustering is very sensitive to the scaling parameter. To solve these problems, a new manifold distance measure and a novel simulated anneal-ing spectral clustering （SASC） algorithm based on the manifold distance measure are proposed. The simulated annealing based on genetic algorithm （SAGA）, characterized by its rapid convergence to the global optimum, is used to cluster the sample points in the spectral mapping space. The proposed algorithm can not only reflect local and global consistency better, but also reduce the sensitivity of spectral clustering to the kernel parameter, which improves the algorithm’s clustering performance. To efficiently apply the algorithm to image segmentation, the Nystrom method is used to reduce the computation complexity. Experimental results show that compared with traditional clustering algorithms and those popular spectral clustering algorithms, the proposed algorithm can achieve better clustering performances on several synthetic datasets, texture images and real images.展开更多
A simple and fast approach based on eigenvalue similarity metric for Polarimetric SAR image segmentation of Land Cover is proposed in this paper. The approach uses eigenvalues of the coherency matrix as to construct s...A simple and fast approach based on eigenvalue similarity metric for Polarimetric SAR image segmentation of Land Cover is proposed in this paper. The approach uses eigenvalues of the coherency matrix as to construct similarity metric of clustering algorithm to segment SAR image. The Mahalanobis distance is used to metric pairwise similarity between pixels to avoid the manual scale parameter tuning in previous spectral clustering method. Furthermore, the spatial coherence constraints and spectral clustering ensemble are employed to stabilize and improve the segmentation performance. All experiments are carried out on three sets of Polarimetric SAR data. The experimental results show that the proposed method is superior to other comparison methods.展开更多
AIM: To determine angle closure agreements between gonioscopy and anterior segment optical coherence tomography(AS-OCT), as well as gonioscopy and spectral domain OCT(SD-OCT). A secondary objective was to quantify int...AIM: To determine angle closure agreements between gonioscopy and anterior segment optical coherence tomography(AS-OCT), as well as gonioscopy and spectral domain OCT(SD-OCT). A secondary objective was to quantify inter-observer agreements of AS-OCT and SD-OCT assessments.METHODS: Seventeen consecutive subjects(33 eyes)were recruited from the study hospital’s Glaucoma clinic.Gonioscopy was performed by a glaucomatologist masked to OCT results. OCT images were read independently by 2 other glaucomatologists masked to gonioscopy findings as well as each other’s analyses of OCT images.RESULTS: Totally 84.8% and 45.5% of scleral spurs were visualized in AS-OCT and SD-OCT images respectively(P 【0.01). The agreement for angle closure between AS-OCT and gonioscopy was fair at k =0.31(95% confidence interval, CI: 0.03-0.59) and k =0.35(95%CI: 0.07-0.63) for reader 1 and 2 respectively. The agreement for angle closure between SD-OCT and gonioscopy was fair at k =0.21(95% CI: 0.07-0.49) and slight at k =0.17(95% CI: 0.08-0.42) for reader 1 and 2 respectively. The inter-reader agreement for angle closure in AS-OCT images was moderate at 0.51(95% CI: 0.13-0.88). The inter-reader agreement for angle closure in SD-OCT images was slight at 0.18(95% CI: 0.08-0.45).CONCLUSION: Significant proportion of scleral spurs were not visualised with SD-OCT imaging resulting in weaker inter-reader agreements. Identifying other angle landmarks in SD-OCT images will allow more consistent angle closure assessments. Gonioscopy and OCT imaging do not always agree in angle closure assessments but have their own advantages, and should be used together and not exclusively.展开更多
This paper studies spectral density estimation of a strictly stationary r-vector valued continuous time series including missing observations. The finite Fourier transform is constructed in L-joint segments of observa...This paper studies spectral density estimation of a strictly stationary r-vector valued continuous time series including missing observations. The finite Fourier transform is constructed in L-joint segments of observations. The modified periodogram is defined and smoothed to estimate the spectral density matrix. We explore the properties of the proposed estimator. Asymptotic distribution is discussed.展开更多
A novel flat-flat resonator consisting of two crystals（Nd：YAG ＋ Nd：YVO4） is established for power scaling in a diode-end-pumped solid-state laser. We systematically compare laser characteristics between multi-seg...A novel flat-flat resonator consisting of two crystals（Nd：YAG ＋ Nd：YVO4） is established for power scaling in a diode-end-pumped solid-state laser. We systematically compare laser characteristics between multi-segmented（Nd：YAG ＋ Nd：YVO4） and conventional composite（Nd：YAG ＋ Nd：YAG） crystals to demonstrate the feasibility of spectral line matching for output power scale-up in end-pumped lasers. A maximum continuous-wave output power of 79.2 W is reported at 1064 nm, with Mx2= 4.82, My2= 5.48, and a pumping power of 136 W in the multi-segmented crystals（Nd：YAG ＋ Nd：YVO4）. Compared to conventional composite crystals（Nd：YAG ＋ Nd：YAG）, the optical-optical conversion efficiency of multi-segmented crystals（Nd：YAG ＋ Nd：YVO4） from 808 nm to 1064 nm is enhanced from 30% to 58.8%,while the laser output sensitivity as affected by the diode-laser temperature is reduced from 55% to 9%.展开更多
文摘AIM：To quantitatively assess narrow anterior chamber angle using spectral-domain anterior segment optical coherence tomography（SD-AS-OCT） and ultrasound biomicroscopy（UBM）,and to evaluate the correlations and consistency between SD-AS-OCT and UBM.· METHODS：Fifty-five eyes from 40 patients were examined.Patients were diagnosed with primary angleclosure glaucoma（PACG） remission（11 eyes from 8patients）,primary angle closure（PAC,20 eyes from 20patients） and PAC suspect（24 eyes from 12 patients）.Each eye was examined by SD-AS-OCT and UBM after laser peripheral iridotomy（LPI）.The measurements of SD-AS-OCT were angle open distance（AOD）,anterior chamber angle（ACA）,trabecular iris angle（TIA）,and trabecular iris space area（TISA）.UBM measurements were AOD and TIA.Correlations of AOD500 and TIA500 between UBM and AS-OCT were assessed.All parameters were analysed by SPSS 16.0 and MedCalc.· RESULTS：ACA,TIA and AOD measured by SD-ASOCT reached a maximum at the temporal quadrant and minimum at the nasal quadrant.Group parameters of AOD500 and AOD750 showed a linear positive correlation,and AOD750 had less variability.UBM outcomes of AOD500 and TIA500 were significantly smaller than those of SD-AS-OCT.The results of the two techniques were correlated at the superior,nasal and inferior quadrants.CONCLUSION：Both UBM and SD-AS-OCT are efficient tools for follow-up during the course of PACG.We recommended using parameters at 750 μm anterior to the sclera spur for the screening and follow-up of PACG and PAC.The two methods might be alternatives to each other.
基金supported by the National Natural Science Foundationof China(61272119)
文摘The similarity measure is crucial to the performance of spectral clustering. The Gaussian kernel function based on the Euclidean distance is usual y adopted as the similarity measure. However, the Euclidean distance measure cannot ful y reveal the complex distribution data, and the result of spectral clustering is very sensitive to the scaling parameter. To solve these problems, a new manifold distance measure and a novel simulated anneal-ing spectral clustering （SASC） algorithm based on the manifold distance measure are proposed. The simulated annealing based on genetic algorithm （SAGA）, characterized by its rapid convergence to the global optimum, is used to cluster the sample points in the spectral mapping space. The proposed algorithm can not only reflect local and global consistency better, but also reduce the sensitivity of spectral clustering to the kernel parameter, which improves the algorithm’s clustering performance. To efficiently apply the algorithm to image segmentation, the Nystrom method is used to reduce the computation complexity. Experimental results show that compared with traditional clustering algorithms and those popular spectral clustering algorithms, the proposed algorithm can achieve better clustering performances on several synthetic datasets, texture images and real images.
文摘A simple and fast approach based on eigenvalue similarity metric for Polarimetric SAR image segmentation of Land Cover is proposed in this paper. The approach uses eigenvalues of the coherency matrix as to construct similarity metric of clustering algorithm to segment SAR image. The Mahalanobis distance is used to metric pairwise similarity between pixels to avoid the manual scale parameter tuning in previous spectral clustering method. Furthermore, the spatial coherence constraints and spectral clustering ensemble are employed to stabilize and improve the segmentation performance. All experiments are carried out on three sets of Polarimetric SAR data. The experimental results show that the proposed method is superior to other comparison methods.
文摘AIM: To determine angle closure agreements between gonioscopy and anterior segment optical coherence tomography(AS-OCT), as well as gonioscopy and spectral domain OCT(SD-OCT). A secondary objective was to quantify inter-observer agreements of AS-OCT and SD-OCT assessments.METHODS: Seventeen consecutive subjects(33 eyes)were recruited from the study hospital’s Glaucoma clinic.Gonioscopy was performed by a glaucomatologist masked to OCT results. OCT images were read independently by 2 other glaucomatologists masked to gonioscopy findings as well as each other’s analyses of OCT images.RESULTS: Totally 84.8% and 45.5% of scleral spurs were visualized in AS-OCT and SD-OCT images respectively(P 【0.01). The agreement for angle closure between AS-OCT and gonioscopy was fair at k =0.31(95% confidence interval, CI: 0.03-0.59) and k =0.35(95%CI: 0.07-0.63) for reader 1 and 2 respectively. The agreement for angle closure between SD-OCT and gonioscopy was fair at k =0.21(95% CI: 0.07-0.49) and slight at k =0.17(95% CI: 0.08-0.42) for reader 1 and 2 respectively. The inter-reader agreement for angle closure in AS-OCT images was moderate at 0.51(95% CI: 0.13-0.88). The inter-reader agreement for angle closure in SD-OCT images was slight at 0.18(95% CI: 0.08-0.45).CONCLUSION: Significant proportion of scleral spurs were not visualised with SD-OCT imaging resulting in weaker inter-reader agreements. Identifying other angle landmarks in SD-OCT images will allow more consistent angle closure assessments. Gonioscopy and OCT imaging do not always agree in angle closure assessments but have their own advantages, and should be used together and not exclusively.
文摘This paper studies spectral density estimation of a strictly stationary r-vector valued continuous time series including missing observations. The finite Fourier transform is constructed in L-joint segments of observations. The modified periodogram is defined and smoothed to estimate the spectral density matrix. We explore the properties of the proposed estimator. Asymptotic distribution is discussed.
基金Project supported by the National Defense Pre-Research Foundation of China(Grant No.9140A020105)
文摘A novel flat-flat resonator consisting of two crystals（Nd：YAG ＋ Nd：YVO4） is established for power scaling in a diode-end-pumped solid-state laser. We systematically compare laser characteristics between multi-segmented（Nd：YAG ＋ Nd：YVO4） and conventional composite（Nd：YAG ＋ Nd：YAG） crystals to demonstrate the feasibility of spectral line matching for output power scale-up in end-pumped lasers. A maximum continuous-wave output power of 79.2 W is reported at 1064 nm, with Mx2= 4.82, My2= 5.48, and a pumping power of 136 W in the multi-segmented crystals（Nd：YAG ＋ Nd：YVO4）. Compared to conventional composite crystals（Nd：YAG ＋ Nd：YAG）, the optical-optical conversion efficiency of multi-segmented crystals（Nd：YAG ＋ Nd：YVO4） from 808 nm to 1064 nm is enhanced from 30% to 58.8%,while the laser output sensitivity as affected by the diode-laser temperature is reduced from 55% to 9%.
