This study takes the students who intend to study for graduate students as the research object,and makes a questionnaire survey on the mathematics learning situation and learning platform of the postgraduate candidate...This study takes the students who intend to study for graduate students as the research object,and makes a questionnaire survey on the mathematics learning situation and learning platform of the postgraduate candidates.Questionnaires were distributed online and offline,and a total of 326 valid questionnaires were collected.Based on 326 questionnaires,this paper analyzes the current learning situation of mathematics in the postgraduate entrance examination and studies the strategies based on the present situation,which points out the direction for the construction of mathematics learning and communication platform based on the needs of postgraduate entrance examination.展开更多
This paper describes in detail three kinds of typical compound braking strategy of wheel motor drive electric vehicle and summarizes the current commonly used strategies based on the three typical strategies developed...This paper describes in detail three kinds of typical compound braking strategy of wheel motor drive electric vehicle and summarizes the current commonly used strategies based on the three typical strategies developed. In the end, a new compound braking strategy is proposed;that is, we take braking mode classify, ECE regulations and SOC value of the battery as an important reference of braking force that joins the motor braking force, as well as we join the different identification models;according to the different braking modes, the purpose is that we can apply the different braking program.展开更多
The reduction of molecular nitrogen(N_(2))to ammonia(NH_(3))under mild conditions is one of the most promising studies in the energy field due to the important role of NH_(3)in modern industry,production,and life.The ...The reduction of molecular nitrogen(N_(2))to ammonia(NH_(3))under mild conditions is one of the most promising studies in the energy field due to the important role of NH_(3)in modern industry,production,and life.The photocatalytic reduction of N_(2)is expected to achieve clean and sustainable NH_(3)production by using clean solar energy.To date,the new photocatalysts for photocatalytic reduction of N_(2)to NH_(3)at room temperature and atmospheric pressure have not been fully developed.The major challenge is to achieve high light-absorption efficiency,conversion efficiency,and stability of photocatalysts.Herein,the methods for measuring produced NH_(3)are compared,and the problems related to possible NH_(3)pollution in photocatalytic systems are mentioned to provide accurate ideas for measuring photocatalytic efficiency.The recent progress of nitrogen reduction reaction(NRR)photocatalysts at ambient temperature and pressure is summarized by introducing charge transfer,migration,and separation in photocatalytic NRR,which provides a guidance for the selection of future photocatalyst.More importantly,we introduce the latest research strategies of photocatalysts in detail,which can guide the preparation and design of photocatalysts with high NRR activity.展开更多
How to put forward advisory suggestions regarded as feasible, workable and acceptable by the State leaders through the integration of the goodwill cherished by our scientists with the blueprint masterminded by the hos...How to put forward advisory suggestions regarded as feasible, workable and acceptable by the State leaders through the integration of the goodwill cherished by our scientists with the blueprint masterminded by the hosts of various R&D projects? It seems to me a problem worthy of our serious consideration. Here I would like to suggest that under the leading group of national S&T affairs, a new organ functionally similar to the State R&D Center be set up. Acting as a counselling team to the group, it must be small in payroll and include by strategists spe-展开更多
The Daming Palace site has an important status and far-reaching influence as a national critical cultural relics protection unit and world cultural heritage.Likewise,as a 5A tourist attraction,it has a unique tourist ...The Daming Palace site has an important status and far-reaching influence as a national critical cultural relics protection unit and world cultural heritage.Likewise,as a 5A tourist attraction,it has a unique tourist attraction.By studying the strategy of improving the tourism experience of the Daming Palace ruins,analyzing the current situation of the utilization of cultural tourism resources and the existing problems,and proposing corresponding solutions,we can contribute to the improvement and enhancement of the tourism experience of the Daming Palace ruins in the future.展开更多
Purpose:In studies of the research process,the association between how researchers conceptualize research and their strategic research agendas has been largely overlooked.This study aims to address this gap.Design/met...Purpose:In studies of the research process,the association between how researchers conceptualize research and their strategic research agendas has been largely overlooked.This study aims to address this gap.Design/methodology/approach:This study analyzes this relationship using a dataset of more than 8,500 researchers across all scientific fields and the globe.It studies the associations between the dimensions of two inventories:the Conceptions of Research Inventory(CoRI)and the Multi-Dimensional Research Agenda Inventory—Revised(MDRAI-R).Findings:The findings show a relatively strong association between researchers’conceptions of research and their research agendas.While all conceptions of research are positively related to scientific ambition,the findings are mixed regarding how the dimensions of the two inventories relate to one another,which is significant for those seeking to understand the knowledge production process better.Research limitations:The study relies on self-reported data,which always carries a risk of response bias.Practical implications:The findings provide a greater understanding of the inner workings of knowledge processes and indicate that the two inventories,whether used individually or in combination,may provide complementary analytical perspectives to research performance indicators.They may thus offer important insights for managers of research environments regarding how to assess the research culture,beliefs,and conceptualizations of individual researchers and research teams when designing strategies to promote specific institutional research focuses and strategies.Originality/value:To the best of the authors’knowledge,this is the first study to associate research agendas and conceptions of research.It is based on a large sample of researchers working worldwide and in all fields of knowledge,which ensures that the findings have a reasonable degree of generalizability to the global population of researchers.展开更多
This paper discusses the optimization and design of the new-energy vehicle transmission systems.Traditional automatic transmission systems suffer from fuel consumption and emissions issues,as well as limitations in th...This paper discusses the optimization and design of the new-energy vehicle transmission systems.Traditional automatic transmission systems suffer from fuel consumption and emissions issues,as well as limitations in the efficiency of mechanical transmission systems.In order to solve these problems,different types of transmission systems are used in new-energy vehicles,including battery electric vehicles(BEV),hybrid electric vehicles(HEV),and fuel cell electric vehicles(FCEV).The key factors for optimizing the transmission systems of new-energy vehicles include battery technology and energy management system,electric motor and electronic control system,energy recovery and reuse technology,and lightweight and aerodynamic design of the vehicle.This paper also introduces methods and tools for designing new-energy vehicle transmission systems,including simulation tools,optimization algorithms and data analysis,as well as experimental verification and testing methods.Besides,new-energy vehicle transmission system designs are proposed,and future challenges and development directions are discussed through case studies.展开更多
This paper studies the significance of setting up color design course in higher vocational education,analyzes the problems existing in the current higher vocational color design course,and probes into the teaching str...This paper studies the significance of setting up color design course in higher vocational education,analyzes the problems existing in the current higher vocational color design course,and probes into the teaching strategies of color design course in higher vocational education.展开更多
Starting from the background of the"Double High Plan"in conjunction with the role of personnel file management in advancing the"Double High Plan",this paper analyzes the current status of personnel...Starting from the background of the"Double High Plan"in conjunction with the role of personnel file management in advancing the"Double High Plan",this paper analyzes the current status of personnel file management in higher vocational colleges and the necessity of personnel management in higher vocational colleges,and explores the effective measures to strengthen the informatization of personnel files management to make it more reasonable,standardized and informatized.展开更多
Stressing the uniqueness and complexity of traditional Chinese medicine(TCM)theory system,this paper analyzes the characteristics of TCM as a discipline from four perspectives:scientific nature,fundamental theory,clin...Stressing the uniqueness and complexity of traditional Chinese medicine(TCM)theory system,this paper analyzes the characteristics of TCM as a discipline from four perspectives:scientific nature,fundamental theory,clinical practice,and pharmacological action.It suggests that when the research strategy of TCM theory is designed,the core theory of TCM should be emphasized on the theoretical research on TCM original thinking theory,TCM theory,Chinese materia medica and formulas,acupuncture and moxibustion,meridians and collaterals,and other related fields.Researchers and practitioners should ensure that the basic research on TCM theory is based on clinical practice,research methods(both traditional and contemporary)are exploited,and methodological innovation is underscored.The rule of TCM development should be followed and the characteristics and advantages of TCM carried forward.Meanwhile,the methods and theory of contemporary science and technology should be exploited to fulfill the goal of inheriting,enriching,and developing the fundamental theory of TCM.展开更多
The issue about how outstanding scientists obtained innovative findings has drawn the interest of researchers in science, policy and scientometrics. Here, we attempt to address this question by using computational met...The issue about how outstanding scientists obtained innovative findings has drawn the interest of researchers in science, policy and scientometrics. Here, we attempt to address this question by using computational methods to measure the cognitive content and concepts of K. Barry Sharpless’ research and estimate the knowledge flow of his click chemistry to other fields. First, we traced Sharpless’ conceptual journey over time through topic modeling approach, mapping and clustering of the epistemic network from distant reading his publications. We find that connectivity and functions, the core features of click chemistry, are embodied in his constant search for simplicity. What makes simplicity possible is his continuous work with collaborators on reactivity and reaction mechanisms. Moreover, citation and link analysis show that click chemistry had a much richer impact on other research fields than what is generally acknowledged, and drew solutions to significant and practical questions back to chemistry from biology.Together with these findings, we propose that the click chemistry philosophy follows the way that values nature’s principle. Chemistry has a clear-cut epistemic domain in modeling Nature. Thus, click chemistry as a concept on doing science beyond a connective technology goes across the boundaries between disciplines and impacts many other fields.展开更多
Advancements in genomics have dramatically accelerated the research on medicinal plants,and the development of herbgenomics has promoted the“Project of 1K Medicinal Plant Genome”to decipher their genetic code.Howeve...Advancements in genomics have dramatically accelerated the research on medicinal plants,and the development of herbgenomics has promoted the“Project of 1K Medicinal Plant Genome”to decipher their genetic code.However,it is difficult to obtain their high-quality whole genomes because of the prevalence of polyploidy and/or high genomic heterozygosity.Whole genomes of 123 medicinal plants were published until September 2022.These published genome sequences were investigated in this review,covering their classification,research teams,ploidy,medicinal functions,and sequencing strategies.More than 1,000 institutes or universities around the world and 50 countries are conducting research on medicinal plant genomes.Diploid species account for a majority of sequenced medicinal plants.The whole genomes of plants in the Poaceae family are the most studied.Almost 40%of the published papers studied species with tonifying,replenishing,and heat-cleaning medicinal effects.Medicinal plants are still in the process of domestication as compared with crops,thereby resulting in unclear genetic backgrounds and the lack of pure lines,thus making their genomes more difficult to complete.In addition,there is still no clear routine framework for a medicinal plant to obtain a high-quality whole genome.Herein,a clear and complete strategy has been originally proposed for creating a high-quality whole genome of medicinal plants.Moreover,whole genome-based biological studies of medicinal plants,including breeding and biosynthesis,were reviewed.We also advocate that a research platform of model medicinal plants should be established to promote the genomics research of medicinal plants.展开更多
Aim:This study aimed to translate a known drug-resistance mechanism of long-term CSFIR inhibition into multicellu-lar biomarkers that can serve as potential therapeutic targets as well as predictive markers for the su...Aim:This study aimed to translate a known drug-resistance mechanism of long-term CSFIR inhibition into multicellu-lar biomarkers that can serve as potential therapeutic targets as well as predictive markers for the survival of glioma patients.Methods:Using existing data from a published mouse study of drug resistance in immunotherapy for glioma,we identified mulicellular differentially expressed genes(DEGs)between drug-sensitive and drug-resistant mice and translated the DEGs in mouse genome to human homolog.We constructed correlation gene networks for drug re-sistance in mice and glioma patients and selected candidate genes via concordance analysis of human with mouse gene networks.Markers of drug resistance and an associated predictive signature for patient survival were developed using regularized Cox models with data of glioma patients from The Cancer Genome Atlas(TCGA)database.Predic-tive performance of the identified predictive signature was evaluated using an independent human dataset from the Chinese Glioma Genome Atlas(CGGA)database.Results:Fourteen genes(CCL22,ADCY2,PDK1,ZFP36,CP,CD2,PLAUR,ACAPI,COL5A1,FAM83D,PBK,FANCA,ANXA7,and TACC3)were identified as genetic biomarkers that were all associated with pathways in glioma progression and drug resistance.Five of the 14 genes(CCL22,ADCY2,PDK1,CD2,and COL5A1)were used to construct a signature that is predictive of patient survival in the proneural subtype GBM patients with an AUC under the time-dependent receiver operating characteristic(ROC)of 2-year survival equal to 0.89.This signature also shows promising predic-tive accuracy for the survival of LGG patients but not for non-proneural type GBMs.Conclusion:Our translational approach can utilize gene correlation networks from multiple types of cells in the tu-mor microenvironment of an imals.The identified biomarkers of drug resistance have good power to predict patient survival in some major subtypes of gliomas(the proneural subtype of GBM and LGG).The expression levels of the biomarkers of drug resistance may be modified for the development of personalized immunotherapies to prolong survival for a large portion of glioma patients.展开更多
基金Tianjin University Students Innovation Training Program(202110061104)Education and Teaching Research and Reform Project of Tianjin Agricultural University(2021-B-04).
文摘This study takes the students who intend to study for graduate students as the research object,and makes a questionnaire survey on the mathematics learning situation and learning platform of the postgraduate candidates.Questionnaires were distributed online and offline,and a total of 326 valid questionnaires were collected.Based on 326 questionnaires,this paper analyzes the current learning situation of mathematics in the postgraduate entrance examination and studies the strategies based on the present situation,which points out the direction for the construction of mathematics learning and communication platform based on the needs of postgraduate entrance examination.
文摘This paper describes in detail three kinds of typical compound braking strategy of wheel motor drive electric vehicle and summarizes the current commonly used strategies based on the three typical strategies developed. In the end, a new compound braking strategy is proposed;that is, we take braking mode classify, ECE regulations and SOC value of the battery as an important reference of braking force that joins the motor braking force, as well as we join the different identification models;according to the different braking modes, the purpose is that we can apply the different braking program.
基金Taishan Scholars Program of Shandong Province,Grant/Award Number:tsqn201812068Higher School Youth Innovation Team of Shandong Province,Grant/Award Number:2019KJA013+1 种基金The Opening Fund of State Key Laboratory of Heavy Oil Processing,Grant/Award Number:SKLOP202002006National Natural Science Foundation of China,Grant/Award Number:51872173。
文摘The reduction of molecular nitrogen(N_(2))to ammonia(NH_(3))under mild conditions is one of the most promising studies in the energy field due to the important role of NH_(3)in modern industry,production,and life.The photocatalytic reduction of N_(2)is expected to achieve clean and sustainable NH_(3)production by using clean solar energy.To date,the new photocatalysts for photocatalytic reduction of N_(2)to NH_(3)at room temperature and atmospheric pressure have not been fully developed.The major challenge is to achieve high light-absorption efficiency,conversion efficiency,and stability of photocatalysts.Herein,the methods for measuring produced NH_(3)are compared,and the problems related to possible NH_(3)pollution in photocatalytic systems are mentioned to provide accurate ideas for measuring photocatalytic efficiency.The recent progress of nitrogen reduction reaction(NRR)photocatalysts at ambient temperature and pressure is summarized by introducing charge transfer,migration,and separation in photocatalytic NRR,which provides a guidance for the selection of future photocatalyst.More importantly,we introduce the latest research strategies of photocatalysts in detail,which can guide the preparation and design of photocatalysts with high NRR activity.
文摘How to put forward advisory suggestions regarded as feasible, workable and acceptable by the State leaders through the integration of the goodwill cherished by our scientists with the blueprint masterminded by the hosts of various R&D projects? It seems to me a problem worthy of our serious consideration. Here I would like to suggest that under the leading group of national S&T affairs, a new organ functionally similar to the State R&D Center be set up. Acting as a counselling team to the group, it must be small in payroll and include by strategists spe-
文摘The Daming Palace site has an important status and far-reaching influence as a national critical cultural relics protection unit and world cultural heritage.Likewise,as a 5A tourist attraction,it has a unique tourist attraction.By studying the strategy of improving the tourism experience of the Daming Palace ruins,analyzing the current situation of the utilization of cultural tourism resources and the existing problems,and proposing corresponding solutions,we can contribute to the improvement and enhancement of the tourism experience of the Daming Palace ruins in the future.
基金supported by doctoral grant PD/BD/113999/2015 from the Fundacao para a Ciência e Tecnologia and by the European Social Fund and the Portuguese Ministry of Science and Educationfunded by the Research Grants Council (Hong Kong SAR, China)project entitled “Characterizing researchers’ research agenda-setting: an international perspective across fields of knowledge” (project number: 27608516)。
文摘Purpose:In studies of the research process,the association between how researchers conceptualize research and their strategic research agendas has been largely overlooked.This study aims to address this gap.Design/methodology/approach:This study analyzes this relationship using a dataset of more than 8,500 researchers across all scientific fields and the globe.It studies the associations between the dimensions of two inventories:the Conceptions of Research Inventory(CoRI)and the Multi-Dimensional Research Agenda Inventory—Revised(MDRAI-R).Findings:The findings show a relatively strong association between researchers’conceptions of research and their research agendas.While all conceptions of research are positively related to scientific ambition,the findings are mixed regarding how the dimensions of the two inventories relate to one another,which is significant for those seeking to understand the knowledge production process better.Research limitations:The study relies on self-reported data,which always carries a risk of response bias.Practical implications:The findings provide a greater understanding of the inner workings of knowledge processes and indicate that the two inventories,whether used individually or in combination,may provide complementary analytical perspectives to research performance indicators.They may thus offer important insights for managers of research environments regarding how to assess the research culture,beliefs,and conceptualizations of individual researchers and research teams when designing strategies to promote specific institutional research focuses and strategies.Originality/value:To the best of the authors’knowledge,this is the first study to associate research agendas and conceptions of research.It is based on a large sample of researchers working worldwide and in all fields of knowledge,which ensures that the findings have a reasonable degree of generalizability to the global population of researchers.
基金funded by the project“Development of New Energy Vehicle Transmission System”(Project number:21013).
文摘This paper discusses the optimization and design of the new-energy vehicle transmission systems.Traditional automatic transmission systems suffer from fuel consumption and emissions issues,as well as limitations in the efficiency of mechanical transmission systems.In order to solve these problems,different types of transmission systems are used in new-energy vehicles,including battery electric vehicles(BEV),hybrid electric vehicles(HEV),and fuel cell electric vehicles(FCEV).The key factors for optimizing the transmission systems of new-energy vehicles include battery technology and energy management system,electric motor and electronic control system,energy recovery and reuse technology,and lightweight and aerodynamic design of the vehicle.This paper also introduces methods and tools for designing new-energy vehicle transmission systems,including simulation tools,optimization algorithms and data analysis,as well as experimental verification and testing methods.Besides,new-energy vehicle transmission system designs are proposed,and future challenges and development directions are discussed through case studies.
文摘This paper studies the significance of setting up color design course in higher vocational education,analyzes the problems existing in the current higher vocational color design course,and probes into the teaching strategies of color design course in higher vocational education.
文摘Starting from the background of the"Double High Plan"in conjunction with the role of personnel file management in advancing the"Double High Plan",this paper analyzes the current status of personnel file management in higher vocational colleges and the necessity of personnel management in higher vocational colleges,and explores the effective measures to strengthen the informatization of personnel files management to make it more reasonable,standardized and informatized.
基金supported by the National Basic Research Program of China(973 Program)(2009CB522700).
文摘Stressing the uniqueness and complexity of traditional Chinese medicine(TCM)theory system,this paper analyzes the characteristics of TCM as a discipline from four perspectives:scientific nature,fundamental theory,clinical practice,and pharmacological action.It suggests that when the research strategy of TCM theory is designed,the core theory of TCM should be emphasized on the theoretical research on TCM original thinking theory,TCM theory,Chinese materia medica and formulas,acupuncture and moxibustion,meridians and collaterals,and other related fields.Researchers and practitioners should ensure that the basic research on TCM theory is based on clinical practice,research methods(both traditional and contemporary)are exploited,and methodological innovation is underscored.The rule of TCM development should be followed and the characteristics and advantages of TCM carried forward.Meanwhile,the methods and theory of contemporary science and technology should be exploited to fulfill the goal of inheriting,enriching,and developing the fundamental theory of TCM.
基金supported by the Research Funds of Happiness Flower ECNU (No. 2019ECNU-XFZH006)the National Social Science Fund of China (No. 19BZX041)+1 种基金the National Natural Science Foundation of China (Nos. 22125103 and 21971065)the Science Technology Commission Shanghai Municipality (Nos. 22JC1401000, 20JC1416800 and 20XD1421500)。
文摘The issue about how outstanding scientists obtained innovative findings has drawn the interest of researchers in science, policy and scientometrics. Here, we attempt to address this question by using computational methods to measure the cognitive content and concepts of K. Barry Sharpless’ research and estimate the knowledge flow of his click chemistry to other fields. First, we traced Sharpless’ conceptual journey over time through topic modeling approach, mapping and clustering of the epistemic network from distant reading his publications. We find that connectivity and functions, the core features of click chemistry, are embodied in his constant search for simplicity. What makes simplicity possible is his continuous work with collaborators on reactivity and reaction mechanisms. Moreover, citation and link analysis show that click chemistry had a much richer impact on other research fields than what is generally acknowledged, and drew solutions to significant and practical questions back to chemistry from biology.Together with these findings, we propose that the click chemistry philosophy follows the way that values nature’s principle. Chemistry has a clear-cut epistemic domain in modeling Nature. Thus, click chemistry as a concept on doing science beyond a connective technology goes across the boundaries between disciplines and impacts many other fields.
基金supported by Scientific and Technological Innovation Project of China Academy of Chinese Medical Sciences(CI2021A03910,CI2021A04106)the National Key Research and Development Program of China(2019YFC1710601)+1 种基金Fundamental Research Funds for the Central Public Welfare Research Institutes of China(ZXKT21026,ZZ15-YQ-033)Major Special Project of Scientific and Technological Cooperation of Bijie City(2021-02)。
文摘Advancements in genomics have dramatically accelerated the research on medicinal plants,and the development of herbgenomics has promoted the“Project of 1K Medicinal Plant Genome”to decipher their genetic code.However,it is difficult to obtain their high-quality whole genomes because of the prevalence of polyploidy and/or high genomic heterozygosity.Whole genomes of 123 medicinal plants were published until September 2022.These published genome sequences were investigated in this review,covering their classification,research teams,ploidy,medicinal functions,and sequencing strategies.More than 1,000 institutes or universities around the world and 50 countries are conducting research on medicinal plant genomes.Diploid species account for a majority of sequenced medicinal plants.The whole genomes of plants in the Poaceae family are the most studied.Almost 40%of the published papers studied species with tonifying,replenishing,and heat-cleaning medicinal effects.Medicinal plants are still in the process of domestication as compared with crops,thereby resulting in unclear genetic backgrounds and the lack of pure lines,thus making their genomes more difficult to complete.In addition,there is still no clear routine framework for a medicinal plant to obtain a high-quality whole genome.Herein,a clear and complete strategy has been originally proposed for creating a high-quality whole genome of medicinal plants.Moreover,whole genome-based biological studies of medicinal plants,including breeding and biosynthesis,were reviewed.We also advocate that a research platform of model medicinal plants should be established to promote the genomics research of medicinal plants.
基金supported by research grants P30CA016087,P50CA225450,P30AG066512 from the National Institute of Health(NIH).
文摘Aim:This study aimed to translate a known drug-resistance mechanism of long-term CSFIR inhibition into multicellu-lar biomarkers that can serve as potential therapeutic targets as well as predictive markers for the survival of glioma patients.Methods:Using existing data from a published mouse study of drug resistance in immunotherapy for glioma,we identified mulicellular differentially expressed genes(DEGs)between drug-sensitive and drug-resistant mice and translated the DEGs in mouse genome to human homolog.We constructed correlation gene networks for drug re-sistance in mice and glioma patients and selected candidate genes via concordance analysis of human with mouse gene networks.Markers of drug resistance and an associated predictive signature for patient survival were developed using regularized Cox models with data of glioma patients from The Cancer Genome Atlas(TCGA)database.Predic-tive performance of the identified predictive signature was evaluated using an independent human dataset from the Chinese Glioma Genome Atlas(CGGA)database.Results:Fourteen genes(CCL22,ADCY2,PDK1,ZFP36,CP,CD2,PLAUR,ACAPI,COL5A1,FAM83D,PBK,FANCA,ANXA7,and TACC3)were identified as genetic biomarkers that were all associated with pathways in glioma progression and drug resistance.Five of the 14 genes(CCL22,ADCY2,PDK1,CD2,and COL5A1)were used to construct a signature that is predictive of patient survival in the proneural subtype GBM patients with an AUC under the time-dependent receiver operating characteristic(ROC)of 2-year survival equal to 0.89.This signature also shows promising predic-tive accuracy for the survival of LGG patients but not for non-proneural type GBMs.Conclusion:Our translational approach can utilize gene correlation networks from multiple types of cells in the tu-mor microenvironment of an imals.The identified biomarkers of drug resistance have good power to predict patient survival in some major subtypes of gliomas(the proneural subtype of GBM and LGG).The expression levels of the biomarkers of drug resistance may be modified for the development of personalized immunotherapies to prolong survival for a large portion of glioma patients.
