Objective: The efficacy of Ji Desheng snake pills combined with hypertonic glucose external application in treating drug-induced superficial phlebitis caused by parenteral nutrition (PN) is observed. Methods: Fifty-tw...Objective: The efficacy of Ji Desheng snake pills combined with hypertonic glucose external application in treating drug-induced superficial phlebitis caused by parenteral nutrition (PN) is observed. Methods: Fifty-two cases of drug-induced superficial phlebitis after peripheral parenteral nutrition (PPN) were selected, which were randomly divided into experimental group and control group in accordance with the phlebitis grading. In the experimental group, Ji Desheng snake pills were crushed to make a paste with 50% glucose solution, which was then applied to the affected area of phlebitis, the surface was covered with clean gauze, and properly fixed with tape or bandage. The drug was replaced once a day. In the control group, the gauze soaked with 50% magnesium sulfate solution was used, which was applied to the affected part three times a day in wet, and the efficacy was observed respectively on the 1st, 3rd, 5th and 7th days after applying the drug. Results: On the 1st and 3rd days after treatment, the observed effective rate of the experimental group was higher than that of the control group (42.31% vs. 15.38% and 76.92% vs. 46.15%, respectively). The difference was statistically significant (p th and 7th days after treatment, there was no statistical significance with respect to the efficacy between the experimental group and the control group (p > 0.05). Conclusion: The significant efficacy could be found in early stage after drug-induced superficial phlebitis was treated by Ji Desheng snake pills combined with hypertonic glucose external application, which was superior to that of the traditional treatment of wet application by using gauze soaked in 50% magnesium sulfate solution.展开更多
目的应用Cox回归模型分析神经内科患者外周浅静脉留置针相关性静脉炎发生的危险因素。方法收集2015年6—8月南京地区3家三级甲等医院神经内科患者外周浅静脉穿刺留置针相关临床资料,采用Cox回归模型对外周浅静脉留置针静脉炎相关因素进...目的应用Cox回归模型分析神经内科患者外周浅静脉留置针相关性静脉炎发生的危险因素。方法收集2015年6—8月南京地区3家三级甲等医院神经内科患者外周浅静脉穿刺留置针相关临床资料,采用Cox回归模型对外周浅静脉留置针静脉炎相关因素进行单因素、多因素分析,建立模型。结果 Cox回归多因素分析显示：高渗透压（HR=7.243,95%CI：4.590~11.429,P〈0.001）、p H〉9（HR=4.683,95%CI：2.274~9.642,P〈0.001）、p H〈5（HR=1.840,95%CI：1.043~3.246,P=0.035）、在肘窝处置管（HR=4.109,95%CI：1.808~9.338,P〈0.001）、每日输注液体总量〉1 500 m L（HR=1.753,95%CI：1.105~2.782,P=0.017）为静脉炎发生的危险因素。建立静脉炎危险因素模型预后指数（PI）为PI=7.243高渗透压药物＋4.683 p H〉9药物＋1.840 p H〈5药物＋4.109在肘窝处置管＋1.753每日输注液体总量〉1 500 m L。PI值越小,静脉炎发生危险性越低;PI值越大,静脉炎发生危险性越高。结论影响神经内科患者静脉炎发生的危险因素为高渗透压（〉600 m Osm/L）、p H〉9、p H〈5、肘窝处置管、每日液体总量〉1 500 m L,并建立回归模型,为正确实施预防静脉炎措施提供参考。展开更多
文摘Objective: The efficacy of Ji Desheng snake pills combined with hypertonic glucose external application in treating drug-induced superficial phlebitis caused by parenteral nutrition (PN) is observed. Methods: Fifty-two cases of drug-induced superficial phlebitis after peripheral parenteral nutrition (PPN) were selected, which were randomly divided into experimental group and control group in accordance with the phlebitis grading. In the experimental group, Ji Desheng snake pills were crushed to make a paste with 50% glucose solution, which was then applied to the affected area of phlebitis, the surface was covered with clean gauze, and properly fixed with tape or bandage. The drug was replaced once a day. In the control group, the gauze soaked with 50% magnesium sulfate solution was used, which was applied to the affected part three times a day in wet, and the efficacy was observed respectively on the 1st, 3rd, 5th and 7th days after applying the drug. Results: On the 1st and 3rd days after treatment, the observed effective rate of the experimental group was higher than that of the control group (42.31% vs. 15.38% and 76.92% vs. 46.15%, respectively). The difference was statistically significant (p th and 7th days after treatment, there was no statistical significance with respect to the efficacy between the experimental group and the control group (p > 0.05). Conclusion: The significant efficacy could be found in early stage after drug-induced superficial phlebitis was treated by Ji Desheng snake pills combined with hypertonic glucose external application, which was superior to that of the traditional treatment of wet application by using gauze soaked in 50% magnesium sulfate solution.
文摘目的应用Cox回归模型分析神经内科患者外周浅静脉留置针相关性静脉炎发生的危险因素。方法收集2015年6—8月南京地区3家三级甲等医院神经内科患者外周浅静脉穿刺留置针相关临床资料,采用Cox回归模型对外周浅静脉留置针静脉炎相关因素进行单因素、多因素分析,建立模型。结果 Cox回归多因素分析显示：高渗透压（HR=7.243,95%CI：4.590~11.429,P〈0.001）、p H〉9（HR=4.683,95%CI：2.274~9.642,P〈0.001）、p H〈5（HR=1.840,95%CI：1.043~3.246,P=0.035）、在肘窝处置管（HR=4.109,95%CI：1.808~9.338,P〈0.001）、每日输注液体总量〉1 500 m L（HR=1.753,95%CI：1.105~2.782,P=0.017）为静脉炎发生的危险因素。建立静脉炎危险因素模型预后指数（PI）为PI=7.243高渗透压药物＋4.683 p H〉9药物＋1.840 p H〈5药物＋4.109在肘窝处置管＋1.753每日输注液体总量〉1 500 m L。PI值越小,静脉炎发生危险性越低;PI值越大,静脉炎发生危险性越高。结论影响神经内科患者静脉炎发生的危险因素为高渗透压（〉600 m Osm/L）、p H〉9、p H〈5、肘窝处置管、每日液体总量〉1 500 m L,并建立回归模型,为正确实施预防静脉炎措施提供参考。
