Recently,weak supervision has received growing attention in the field of salient object detection due to the convenience of labelling.However,there is a large performance gap between weakly supervised and fully superv...Recently,weak supervision has received growing attention in the field of salient object detection due to the convenience of labelling.However,there is a large performance gap between weakly supervised and fully supervised salient object detectors because the scribble annotation can only provide very limited foreground/background information.Therefore,an intuitive idea is to infer annotations that cover more complete object and background regions for training.To this end,a label inference strategy is proposed based on the assumption that pixels with similar colours and close positions should have consistent labels.Specifically,k-means clustering algorithm was first performed on both colours and coordinates of original annotations,and then assigned the same labels to points having similar colours with colour cluster centres and near coordinate cluster centres.Next,the same annotations for pixels with similar colours within each kernel neighbourhood was set further.Extensive experiments on six benchmarks demonstrate that our method can significantly improve the performance and achieve the state-of-the-art results.展开更多
The coronavirus disease 2019(COVID-19)has severely disrupted both human life and the health care system.Timely diagnosis and treatment have become increasingly important;however,the distribution and size of lesions va...The coronavirus disease 2019(COVID-19)has severely disrupted both human life and the health care system.Timely diagnosis and treatment have become increasingly important;however,the distribution and size of lesions vary widely among individuals,making it challenging to accurately diagnose the disease.This study proposed a deep-learning disease diagnosismodel based onweakly supervised learning and clustering visualization(W_CVNet)that fused classification with segmentation.First,the data were preprocessed.An optimizable weakly supervised segmentation preprocessing method(O-WSSPM)was used to remove redundant data and solve the category imbalance problem.Second,a deep-learning fusion method was used for feature extraction and classification recognition.A dual asymmetric complementary bilinear feature extraction method(D-CBM)was used to fully extract complementary features,which solved the problem of insufficient feature extraction by a single deep learning network.Third,an unsupervised learning method based on Fuzzy C-Means(FCM)clustering was used to segment and visualize COVID-19 lesions enabling physicians to accurately assess lesion distribution and disease severity.In this study,5-fold cross-validation methods were used,and the results showed that the network had an average classification accuracy of 85.8%,outperforming six recent advanced classification models.W_CVNet can effectively help physicians with automated aid in diagnosis to determine if the disease is present and,in the case of COVID-19 patients,to further predict the area of the lesion.展开更多
N-11-azaartemisinins potentially active against Plasmodium falciparum are designed by combining molecular electrostatic potential (MEP), ligand-receptor interaction, and models built with supervised machine learning m...N-11-azaartemisinins potentially active against Plasmodium falciparum are designed by combining molecular electrostatic potential (MEP), ligand-receptor interaction, and models built with supervised machine learning methods (PCA, HCA, KNN, SIMCA, and SDA). The optimization of molecular structures was performed using the B3LYP/6-31G* approach. MEP maps and ligand-receptor interactions were used to investigate key structural features required for biological activities and likely interactions between N-11-azaartemisinins and heme, respectively. The supervised machine learning methods allowed the separation of the investigated compounds into two classes: cha and cla, with the properties ε<sub>LUMO+1</sub> (one level above lowest unoccupied molecular orbital energy), d(C<sub>6</sub>-C<sub>5</sub>) (distance between C<sub>6</sub> and C<sub>5</sub> atoms in ligands), and TSA (total surface area) responsible for the classification. The insights extracted from the investigation developed and the chemical intuition enabled the design of sixteen new N-11-azaartemisinins (prediction set), moreover, models built with supervised machine learning methods were applied to this prediction set. The result of this application showed twelve new promising N-11-azaartemisinins for synthesis and biological evaluation.展开更多
Single-molecule force spectroscopy(SMFS)measurements of the dynamics of biomolecules typically require identifying massive events and states from large data sets,such as extracting rupture forces from force-extension ...Single-molecule force spectroscopy(SMFS)measurements of the dynamics of biomolecules typically require identifying massive events and states from large data sets,such as extracting rupture forces from force-extension curves(FECs)in pulling experiments and identifying states from extension-time trajectories(ETTs)in force-clamp experiments.The former is often accomplished manually and hence is time-consuming and laborious while the latter is always impeded by the presence of baseline drift.In this study,we attempt to accurately and automatically identify the events and states from SMFS experiments with a machine learning approach,which combines clustering and classification for event identification of SMFS(ACCESS).As demonstrated by analysis of a series of data sets,ACCESS can extract the rupture forces from FECs containing multiple unfolding steps and classify the rupture forces into the corresponding conformational transitions.Moreover,ACCESS successfully identifies the unfolded and folded states even though the ETTs display severe nonmonotonic baseline drift.Besides,ACCESS is straightforward in use as it requires only three easy-to-interpret parameters.As such,we anticipate that ACCESS will be a useful,easy-to-implement and high-performance tool for event and state identification across a range of single-molecule experiments.展开更多
Rare labeled data are difficult to recognize by using conventional methods in the process of radar emitter recogni-tion.To solve this problem,an optimized cooperative semi-supervised learning radar emitter recognition...Rare labeled data are difficult to recognize by using conventional methods in the process of radar emitter recogni-tion.To solve this problem,an optimized cooperative semi-supervised learning radar emitter recognition method based on a small amount of labeled data is developed.First,a small amount of labeled data are randomly sampled by using the bootstrap method,loss functions for three common deep learning net-works are improved,the uniform distribution and cross-entropy function are combined to reduce the overconfidence of softmax classification.Subsequently,the dataset obtained after sam-pling is adopted to train three improved networks so as to build the initial model.In addition,the unlabeled data are preliminarily screened through dynamic time warping(DTW)and then input into the initial model trained previously for judgment.If the judg-ment results of two or more networks are consistent,the unla-beled data are labeled and put into the labeled data set.Lastly,the three network models are input into the labeled dataset for training,and the final model is built.As revealed by the simula-tion results,the semi-supervised learning method adopted in this paper is capable of exploiting a small amount of labeled data and basically achieving the accuracy of labeled data recognition.展开更多
A large variety of complaint reports reflect subjective information expressed by citizens.A key challenge of text summarization for complaint reports is to ensure the factual consistency of generated summary.Therefore...A large variety of complaint reports reflect subjective information expressed by citizens.A key challenge of text summarization for complaint reports is to ensure the factual consistency of generated summary.Therefore,in this paper,a simple and weakly supervised framework considering factual consistency is proposed to generate a summary of city-based complaint reports without pre-labeled sentences/words.Furthermore,it considers the importance of entity in complaint reports to ensure factual consistency of summary.Experimental results on the customer review datasets(Yelp and Amazon)and complaint report dataset(complaint reports of Shenyang in China)show that the proposed framework outperforms state-of-the-art approaches in ROUGE scores and human evaluation.It unveils the effectiveness of our approach to helping in dealing with complaint reports.展开更多
Contrastive self‐supervised representation learning on attributed graph networks with Graph Neural Networks has attracted considerable research interest recently.However,there are still two challenges.First,most of t...Contrastive self‐supervised representation learning on attributed graph networks with Graph Neural Networks has attracted considerable research interest recently.However,there are still two challenges.First,most of the real‐word system are multiple relations,where entities are linked by different types of relations,and each relation is a view of the graph network.Second,the rich multi‐scale information(structure‐level and feature‐level)of the graph network can be seen as self‐supervised signals,which are not fully exploited.A novel contrastive self‐supervised representation learning framework on attributed multiplex graph networks with multi‐scale(named CoLM^(2)S)information is presented in this study.It mainly contains two components:intra‐relation contrast learning and interrelation contrastive learning.Specifically,the contrastive self‐supervised representation learning framework on attributed single‐layer graph networks with multi‐scale information(CoLMS)framework with the graph convolutional network as encoder to capture the intra‐relation information with multi‐scale structure‐level and feature‐level selfsupervised signals is introduced first.The structure‐level information includes the edge structure and sub‐graph structure,and the feature‐level information represents the output of different graph convolutional layer.Second,according to the consensus assumption among inter‐relations,the CoLM^(2)S framework is proposed to jointly learn various graph relations in attributed multiplex graph network to achieve global consensus node embedding.The proposed method can fully distil the graph information.Extensive experiments on unsupervised node clustering and graph visualisation tasks demonstrate the effectiveness of our methods,and it outperforms existing competitive baselines.展开更多
Nowadays, in data science, supervised learning algorithms are frequently used to perform text classification. However, African textual data, in general, have been studied very little using these methods. This article ...Nowadays, in data science, supervised learning algorithms are frequently used to perform text classification. However, African textual data, in general, have been studied very little using these methods. This article notes the particularity of the data and measures the level of precision of predictions of naive Bayes algorithms, decision tree, and SVM (Support Vector Machine) on a corpus of computer jobs taken on the internet. This is due to the data imbalance problem in machine learning. However, this problem essentially focuses on the distribution of the number of documents in each class or subclass. Here, we delve deeper into the problem to the word count distribution in a set of documents. The results are compared with those obtained on a set of French IT offers. It appears that the precision of the classification varies between 88% and 90% for French offers against 67%, at most, for Cameroonian offers. The contribution of this study is twofold. Indeed, it clearly shows that, in a similar job category, job offers on the internet in Cameroon are more unstructured compared to those available in France, for example. Moreover, it makes it possible to emit a strong hypothesis according to which sets of texts having a symmetrical distribution of the number of words obtain better results with supervised learning algorithms.展开更多
In recent years, the place occupied by the various manifestations of cyber-crime in companies has been considerable. Indeed, due to the rapid evolution of telecommunications technologies, companies, regardless of thei...In recent years, the place occupied by the various manifestations of cyber-crime in companies has been considerable. Indeed, due to the rapid evolution of telecommunications technologies, companies, regardless of their size or sector of activity, are now the target of advanced persistent threats. The Work 2035 study also revealed that cyber crimes (such as critical infrastructure hacks) and massive data breaches are major sources of concern. Thus, it is important for organizations to guarantee a minimum level of security to avoid potential attacks that can cause paralysis of systems, loss of sensitive data, exposure to blackmail, damage to reputation or even a commercial harm. To do this, among other means, hardening is used, the main objective of which is to reduce the attack surface within a company. The execution of the hardening configurations as well as the verification of these are carried out on the servers and network equipment with the aim of reducing the number of openings present by keeping only those which are necessary for proper operation. However, nowadays, in many companies, these tasks are done manually. As a result, the execution and verification of hardening configurations are very often subject to potential errors but also highly consuming human and financial resources. The problem is that it is essential for operators to maintain an optimal level of security while minimizing costs, hence the interest in automating hardening processes and verifying the hardening of servers and network equipment. It is in this logic that we propose within the framework of this work the reinforcement of the security of the information systems (IS) by the automation of the mechanisms of hardening. In our work, we have, on the one hand, set up a hardening procedure in accordance with international security standards for servers, routers and switches and, on the other hand, designed and produced a functional application which makes it possible to: 1) Realise the configuration of the hardening;2) Verify them;3) Correct the non conformities;4) Write and send by mail a verification report for the configurations;5) And finally update the procedures of hardening. Our web application thus created allows in less than fifteen (15) minutes actions that previously took at least five (5) hours of time. This allows supervised network operators to save time and money, but also to improve their security standards in line with international standards.展开更多
In order to solve the problem of automatic defect detection and process control in the welding and arc additive process,the paper monitors the current,voltage,audio,and other data during the welding process and extrac...In order to solve the problem of automatic defect detection and process control in the welding and arc additive process,the paper monitors the current,voltage,audio,and other data during the welding process and extracts the minimum value,standard deviation,deviation from the voltage and current data.It extracts spectral features such as root mean square,spectral centroid,and zero-crossing rate from audio data,fuses the features extracted from multiple sensor signals,and establishes multiple machine learning supervised and unsupervised models.They are used to detect abnormalities in the welding process.The experimental results show that the established multiple machine learning models have high accuracy,among which the supervised learning model,the balanced accuracy of Ada boost is 0.957,and the unsupervised learning model Isolation Forest has a balanced accuracy of 0.909.展开更多
We have presented an integrated approach based on supervised and unsupervised learning tech- nique to improve the accuracy of six predictive models. They are developed to predict outcome of tuberculosis treatment cour...We have presented an integrated approach based on supervised and unsupervised learning tech- nique to improve the accuracy of six predictive models. They are developed to predict outcome of tuberculosis treatment course and their accuracy needs to be improved as they are not precise as much as necessary. The integrated supervised and unsupervised learning method (ISULM) has been proposed as a new way to improve model accuracy. The dataset of 6450 Iranian TB patients under DOTS therapy was applied to initially select the significant predictors and then develop six predictive models using decision tree, Bayesian network, logistic regression, multilayer perceptron, radial basis function, and support vector machine algorithms. Developed models have integrated with k-mean clustering analysis to calculate more accurate predicted outcome of tuberculosis treatment course. Obtained results, then, have been evaluated to compare prediction accuracy before and after ISULM application. Recall, Precision, F-measure, and ROC area are other criteria used to assess the models validity as well as change percentage to show how different are models before and after ISULM. ISULM led to improve the prediction accuracy for all applied classifiers ranging between 4% and 10%. The most and least improvement for prediction accuracy were shown by logistic regression and support vector machine respectively. Pre-learning by k- mean clustering to relocate the objects and put similar cases in the same group can improve the classification accuracy in the process of integrating supervised and unsupervised learning.展开更多
Detecting naturally arising structures in data is central to knowledge extraction from data. In most applications, the main challenge is in the choice of the appropriate model for exploring the data features. The choi...Detecting naturally arising structures in data is central to knowledge extraction from data. In most applications, the main challenge is in the choice of the appropriate model for exploring the data features. The choice is generally poorly understood and any tentative choice may be too restrictive. Growing volumes of data, disparate data sources and modelling techniques entail the need for model optimization via adaptability rather than comparability. We propose a novel two-stage algorithm to modelling continuous data consisting of an unsupervised stage whereby the algorithm searches through the data for optimal parameter values and a supervised stage that adapts the parameters for predictive modelling. The method is implemented on the sunspots data with inherently Gaussian distributional properties and assumed bi-modality. Optimal values separating high from lows cycles are obtained via multiple simulations. Early patterns for each recorded cycle reveal that the first 3 years provide a sufficient basis for predicting the peak. Multiple Support Vector Machine runs using repeatedly improved data parameters show that the approach yields greater accuracy and reliability than conventional approaches and provides a good basis for model selection. Model reliability is established via multiple simulations of this type.展开更多
The purpose of this study was to explore the effects of supervised movie appreciation on improving the life meaning sense among college students. The intervention combined by “pre-video, post counseling” was conduct...The purpose of this study was to explore the effects of supervised movie appreciation on improving the life meaning sense among college students. The intervention combined by “pre-video, post counseling” was conducted on the experimental group, while the control group received no intervention. Results have shown that the scores on the subscales of will to meaning, life purpose, life control, suffer acceptance and on the total scale have improved significantly. No gender difference was found on the intervention effect, and participants receiving intervention maintained higher level on related subscales a week later, indicating that supervised movie appreciation is an effective way to improve the life meaning sense among college students.展开更多
In order to obtain a high-quality weld during the laser welding process, extracting the characteristic parameters of weld pool is an important issue for automated welding. In this paper, the type 304 austenitic stainl...In order to obtain a high-quality weld during the laser welding process, extracting the characteristic parameters of weld pool is an important issue for automated welding. In this paper, the type 304 austenitic stainless steel is welded by a 5 kW high-power fiber laser and a high-speed camera is employed to capture the topside images of weld pools. Then we propose a robust visual-detection approach for the molten pool based on the supervised descent method. It provides an elegant framework for representing the outline of a weld pool and is especially efficient for weld pool detection in the presence of strong uncertainties and disturbances. Finally, welding experimental results verified that the proposed approach can extract the weld pool boundary accurately, which will lay a solid foundation for controlling the weld quality of fiber laser welding process.展开更多
AIM To evaluate the effect of a 12-mo supervised aerobic and resistance training, on renal function and exercise capacity compared to usual care recommendations.METHODS Ninety-nine kidney transplant recipients(KTRs) w...AIM To evaluate the effect of a 12-mo supervised aerobic and resistance training, on renal function and exercise capacity compared to usual care recommendations.METHODS Ninety-nine kidney transplant recipients(KTRs) were assigned to interventional exercise(Group A; n = 52) and a usual care cohort(Group B; n = 47). Blood and urine chemistry, exercise capacity, muscular strength, anthropometric measures and health-related quality of life(HRQo L) were assessed at baseline, and after 6 and 12 mo. Group A underwent a supervised training three times per week for 12 mo. Group B received only general recommendations about home-based physical activities.RESULTS Eighty-five KTRs completed the study(Group A, n = 44; Group B, n = 41). After 12 mo, renal function remained stable in both groups. Group A significantly increased maximum workload(+13 W, P = 0.0003), V'O2 peak(+3.1 mL/kg per minute, P = 0.0099), muscular strength in plantar flexor(+12 kg, P = 0.0368), height in the countermovement jump(+1.9 cm, P = 0.0293) and decreased in Body Mass Index(-0.5 kg/m^2, P = 0.0013). HRQo L significantly improved in physical function(P = 0.0019), physical-role limitations(P = 0.0321) and social functioning scales(P = 0.0346). Noimprovements were found in Group B.CONCLUSION Twelve-month of supervised aerobic and resistance training improves the physiological variables related to physical fitness and cardiovascular risks without consequences on renal function. Recommendations alone are not sufficient to induce changes in exercise capacity of KTRs. Our study is an example of collaborative working between transplant centres, sports medicine and exercise facilities.展开更多
Recently,video object segmentation has received great attention in the computer vision community.Most of the existing methods heavily rely on the pixel-wise human annotations,which are expensive and time-consuming to ...Recently,video object segmentation has received great attention in the computer vision community.Most of the existing methods heavily rely on the pixel-wise human annotations,which are expensive and time-consuming to obtain.To tackle this problem,we make an early attempt to achieve video object segmentation with scribble-level supervision,which can alleviate large amounts of human labor for collecting the manual annotation.However,using conventional network architectures and learning objective functions under this scenario cannot work well as the supervision information is highly sparse and incomplete.To address this issue,this paper introduces two novel elements to learn the video object segmentation model.The first one is the scribble attention module,which captures more accurate context information and learns an effective attention map to enhance the contrast between foreground and background.The other one is the scribble-supervised loss,which can optimize the unlabeled pixels and dynamically correct inaccurate segmented areas during the training stage.To evaluate the proposed method,we implement experiments on two video object segmentation benchmark datasets,You Tube-video object segmentation(VOS),and densely annotated video segmentation(DAVIS)-2017.We first generate the scribble annotations from the original per-pixel annotations.Then,we train our model and compare its test performance with the baseline models and other existing works.Extensive experiments demonstrate that the proposed method can work effectively and approach to the methods requiring the dense per-pixel annotations.展开更多
This study proposes a supervised learning method that does not rely on labels.We use variables associated with the label as indirect labels,and construct an indirect physics-constrained loss based on the physical mech...This study proposes a supervised learning method that does not rely on labels.We use variables associated with the label as indirect labels,and construct an indirect physics-constrained loss based on the physical mechanism to train the model.In the training process,the model prediction is mapped to the space of value that conforms to the physical mechanism through the projection matrix,and then the model is trained based on the indirect labels.The final prediction result of the model conforms to the physical mechanism between indirect label and label,and also meets the constraints of the indirect label.The present study also develops projection matrix normalization and prediction covariance analysis to ensure that the model can be fully trained.Finally,the effect of the physics-constrained indirect supervised learning is verified based on a well log generation problem.展开更多
A method that applies clustering technique to reduce the number of samples of large data sets using input-output clustering is proposed.The proposed method clusters the output data into groups and clusters the input d...A method that applies clustering technique to reduce the number of samples of large data sets using input-output clustering is proposed.The proposed method clusters the output data into groups and clusters the input data in accordance with the groups of output data.Then,a set of prototypes are selected from the clustered input data.The inessential data can be ultimately discarded from the data set.The proposed method can reduce the effect from outliers because only the prototypes are used.This method is applied to reduce the data set in regression problems.Two standard synthetic data sets and three standard real-world data sets are used for evaluation.The root-mean-square errors are compared from support vector regression models trained with the original data sets and the corresponding instance-reduced data sets.From the experiments,the proposed method provides good results on the reduction and the reconstruction of the standard synthetic and real-world data sets.The numbers of instances of the synthetic data sets are decreased by 25%-69%.The reduction rates for the real-world data sets of the automobile miles per gallon and the 1990 census in CA are 46% and 57%,respectively.The reduction rate of 96% is very good for the electrocardiogram(ECG) data set because of the redundant and periodic nature of ECG signals.For all of the data sets,the regression results are similar to those from the corresponding original data sets.Therefore,the regression performance of the proposed method is good while only a fraction of the data is needed in the training process.展开更多
The motivation for this article is to propose new damage classifiers based on a supervised learning problem for locating and quantifying damage.A new feature extraction approach using time series analysis is introduce...The motivation for this article is to propose new damage classifiers based on a supervised learning problem for locating and quantifying damage.A new feature extraction approach using time series analysis is introduced to extract damage-sensitive features from auto-regressive models.This approach sets out to improve current feature extraction techniques in the context of time series modeling.The coefficients and residuals of the AR model obtained from the proposed approach are selected as the main features and are applied to the proposed supervised learning classifiers that are categorized as coefficient-based and residual-based classifiers.These classifiers compute the relative errors in the extracted features between the undamaged and damaged states.Eventually,the abilities of the proposed methods to localize and quantify single and multiple damage scenarios are verified by applying experimental data for a laboratory frame and a four-story steel structure.Comparative analyses are performed to validate the superiority of the proposed methods over some existing techniques.Results show that the proposed classifiers,with the aid of extracted features from the proposed feature extraction approach,are able to locate and quantify damage;however,the residual-based classifiers yield better results than the coefficient-based classifiers.Moreover,these methods are superior to some classical techniques.展开更多
文摘Recently,weak supervision has received growing attention in the field of salient object detection due to the convenience of labelling.However,there is a large performance gap between weakly supervised and fully supervised salient object detectors because the scribble annotation can only provide very limited foreground/background information.Therefore,an intuitive idea is to infer annotations that cover more complete object and background regions for training.To this end,a label inference strategy is proposed based on the assumption that pixels with similar colours and close positions should have consistent labels.Specifically,k-means clustering algorithm was first performed on both colours and coordinates of original annotations,and then assigned the same labels to points having similar colours with colour cluster centres and near coordinate cluster centres.Next,the same annotations for pixels with similar colours within each kernel neighbourhood was set further.Extensive experiments on six benchmarks demonstrate that our method can significantly improve the performance and achieve the state-of-the-art results.
基金funded by the Open Foundation of Anhui EngineeringResearch Center of Intelligent Perception and Elderly Care,Chuzhou University(No.2022OPA03)the Higher EducationNatural Science Foundation of Anhui Province(No.KJ2021B01)and the Innovation Team Projects of Universities in Guangdong(No.2022KCXTD057).
文摘The coronavirus disease 2019(COVID-19)has severely disrupted both human life and the health care system.Timely diagnosis and treatment have become increasingly important;however,the distribution and size of lesions vary widely among individuals,making it challenging to accurately diagnose the disease.This study proposed a deep-learning disease diagnosismodel based onweakly supervised learning and clustering visualization(W_CVNet)that fused classification with segmentation.First,the data were preprocessed.An optimizable weakly supervised segmentation preprocessing method(O-WSSPM)was used to remove redundant data and solve the category imbalance problem.Second,a deep-learning fusion method was used for feature extraction and classification recognition.A dual asymmetric complementary bilinear feature extraction method(D-CBM)was used to fully extract complementary features,which solved the problem of insufficient feature extraction by a single deep learning network.Third,an unsupervised learning method based on Fuzzy C-Means(FCM)clustering was used to segment and visualize COVID-19 lesions enabling physicians to accurately assess lesion distribution and disease severity.In this study,5-fold cross-validation methods were used,and the results showed that the network had an average classification accuracy of 85.8%,outperforming six recent advanced classification models.W_CVNet can effectively help physicians with automated aid in diagnosis to determine if the disease is present and,in the case of COVID-19 patients,to further predict the area of the lesion.
文摘N-11-azaartemisinins potentially active against Plasmodium falciparum are designed by combining molecular electrostatic potential (MEP), ligand-receptor interaction, and models built with supervised machine learning methods (PCA, HCA, KNN, SIMCA, and SDA). The optimization of molecular structures was performed using the B3LYP/6-31G* approach. MEP maps and ligand-receptor interactions were used to investigate key structural features required for biological activities and likely interactions between N-11-azaartemisinins and heme, respectively. The supervised machine learning methods allowed the separation of the investigated compounds into two classes: cha and cla, with the properties ε<sub>LUMO+1</sub> (one level above lowest unoccupied molecular orbital energy), d(C<sub>6</sub>-C<sub>5</sub>) (distance between C<sub>6</sub> and C<sub>5</sub> atoms in ligands), and TSA (total surface area) responsible for the classification. The insights extracted from the investigation developed and the chemical intuition enabled the design of sixteen new N-11-azaartemisinins (prediction set), moreover, models built with supervised machine learning methods were applied to this prediction set. The result of this application showed twelve new promising N-11-azaartemisinins for synthesis and biological evaluation.
基金the support from the Physical Research Platform in the School of Physics of Sun Yat-sen University(PRPSP,SYSU)Project supported by the National Natural Science Foundation of China(Grant No.12074445)the Open Fund of the State Key Laboratory of Optoelectronic Materials and Technologies of Sun Yat-sen University(Grant No.OEMT-2022-ZTS-05)。
文摘Single-molecule force spectroscopy(SMFS)measurements of the dynamics of biomolecules typically require identifying massive events and states from large data sets,such as extracting rupture forces from force-extension curves(FECs)in pulling experiments and identifying states from extension-time trajectories(ETTs)in force-clamp experiments.The former is often accomplished manually and hence is time-consuming and laborious while the latter is always impeded by the presence of baseline drift.In this study,we attempt to accurately and automatically identify the events and states from SMFS experiments with a machine learning approach,which combines clustering and classification for event identification of SMFS(ACCESS).As demonstrated by analysis of a series of data sets,ACCESS can extract the rupture forces from FECs containing multiple unfolding steps and classify the rupture forces into the corresponding conformational transitions.Moreover,ACCESS successfully identifies the unfolded and folded states even though the ETTs display severe nonmonotonic baseline drift.Besides,ACCESS is straightforward in use as it requires only three easy-to-interpret parameters.As such,we anticipate that ACCESS will be a useful,easy-to-implement and high-performance tool for event and state identification across a range of single-molecule experiments.
文摘Rare labeled data are difficult to recognize by using conventional methods in the process of radar emitter recogni-tion.To solve this problem,an optimized cooperative semi-supervised learning radar emitter recognition method based on a small amount of labeled data is developed.First,a small amount of labeled data are randomly sampled by using the bootstrap method,loss functions for three common deep learning net-works are improved,the uniform distribution and cross-entropy function are combined to reduce the overconfidence of softmax classification.Subsequently,the dataset obtained after sam-pling is adopted to train three improved networks so as to build the initial model.In addition,the unlabeled data are preliminarily screened through dynamic time warping(DTW)and then input into the initial model trained previously for judgment.If the judg-ment results of two or more networks are consistent,the unla-beled data are labeled and put into the labeled data set.Lastly,the three network models are input into the labeled dataset for training,and the final model is built.As revealed by the simula-tion results,the semi-supervised learning method adopted in this paper is capable of exploiting a small amount of labeled data and basically achieving the accuracy of labeled data recognition.
基金supported by National Natural Science Foundation of China(62276058,61902057,41774063)Fundamental Research Funds for the Central Universities(N2217003)Joint Fund of Science&Technology Department of Liaoning Province and State Key Laboratory of Robotics,China(2020-KF-12-11).
文摘A large variety of complaint reports reflect subjective information expressed by citizens.A key challenge of text summarization for complaint reports is to ensure the factual consistency of generated summary.Therefore,in this paper,a simple and weakly supervised framework considering factual consistency is proposed to generate a summary of city-based complaint reports without pre-labeled sentences/words.Furthermore,it considers the importance of entity in complaint reports to ensure factual consistency of summary.Experimental results on the customer review datasets(Yelp and Amazon)and complaint report dataset(complaint reports of Shenyang in China)show that the proposed framework outperforms state-of-the-art approaches in ROUGE scores and human evaluation.It unveils the effectiveness of our approach to helping in dealing with complaint reports.
基金support by the National Natural Science Foundation of China(NSFC)under grant number 61873274.
文摘Contrastive self‐supervised representation learning on attributed graph networks with Graph Neural Networks has attracted considerable research interest recently.However,there are still two challenges.First,most of the real‐word system are multiple relations,where entities are linked by different types of relations,and each relation is a view of the graph network.Second,the rich multi‐scale information(structure‐level and feature‐level)of the graph network can be seen as self‐supervised signals,which are not fully exploited.A novel contrastive self‐supervised representation learning framework on attributed multiplex graph networks with multi‐scale(named CoLM^(2)S)information is presented in this study.It mainly contains two components:intra‐relation contrast learning and interrelation contrastive learning.Specifically,the contrastive self‐supervised representation learning framework on attributed single‐layer graph networks with multi‐scale information(CoLMS)framework with the graph convolutional network as encoder to capture the intra‐relation information with multi‐scale structure‐level and feature‐level selfsupervised signals is introduced first.The structure‐level information includes the edge structure and sub‐graph structure,and the feature‐level information represents the output of different graph convolutional layer.Second,according to the consensus assumption among inter‐relations,the CoLM^(2)S framework is proposed to jointly learn various graph relations in attributed multiplex graph network to achieve global consensus node embedding.The proposed method can fully distil the graph information.Extensive experiments on unsupervised node clustering and graph visualisation tasks demonstrate the effectiveness of our methods,and it outperforms existing competitive baselines.
文摘Nowadays, in data science, supervised learning algorithms are frequently used to perform text classification. However, African textual data, in general, have been studied very little using these methods. This article notes the particularity of the data and measures the level of precision of predictions of naive Bayes algorithms, decision tree, and SVM (Support Vector Machine) on a corpus of computer jobs taken on the internet. This is due to the data imbalance problem in machine learning. However, this problem essentially focuses on the distribution of the number of documents in each class or subclass. Here, we delve deeper into the problem to the word count distribution in a set of documents. The results are compared with those obtained on a set of French IT offers. It appears that the precision of the classification varies between 88% and 90% for French offers against 67%, at most, for Cameroonian offers. The contribution of this study is twofold. Indeed, it clearly shows that, in a similar job category, job offers on the internet in Cameroon are more unstructured compared to those available in France, for example. Moreover, it makes it possible to emit a strong hypothesis according to which sets of texts having a symmetrical distribution of the number of words obtain better results with supervised learning algorithms.
文摘In recent years, the place occupied by the various manifestations of cyber-crime in companies has been considerable. Indeed, due to the rapid evolution of telecommunications technologies, companies, regardless of their size or sector of activity, are now the target of advanced persistent threats. The Work 2035 study also revealed that cyber crimes (such as critical infrastructure hacks) and massive data breaches are major sources of concern. Thus, it is important for organizations to guarantee a minimum level of security to avoid potential attacks that can cause paralysis of systems, loss of sensitive data, exposure to blackmail, damage to reputation or even a commercial harm. To do this, among other means, hardening is used, the main objective of which is to reduce the attack surface within a company. The execution of the hardening configurations as well as the verification of these are carried out on the servers and network equipment with the aim of reducing the number of openings present by keeping only those which are necessary for proper operation. However, nowadays, in many companies, these tasks are done manually. As a result, the execution and verification of hardening configurations are very often subject to potential errors but also highly consuming human and financial resources. The problem is that it is essential for operators to maintain an optimal level of security while minimizing costs, hence the interest in automating hardening processes and verifying the hardening of servers and network equipment. It is in this logic that we propose within the framework of this work the reinforcement of the security of the information systems (IS) by the automation of the mechanisms of hardening. In our work, we have, on the one hand, set up a hardening procedure in accordance with international security standards for servers, routers and switches and, on the other hand, designed and produced a functional application which makes it possible to: 1) Realise the configuration of the hardening;2) Verify them;3) Correct the non conformities;4) Write and send by mail a verification report for the configurations;5) And finally update the procedures of hardening. Our web application thus created allows in less than fifteen (15) minutes actions that previously took at least five (5) hours of time. This allows supervised network operators to save time and money, but also to improve their security standards in line with international standards.
文摘In order to solve the problem of automatic defect detection and process control in the welding and arc additive process,the paper monitors the current,voltage,audio,and other data during the welding process and extracts the minimum value,standard deviation,deviation from the voltage and current data.It extracts spectral features such as root mean square,spectral centroid,and zero-crossing rate from audio data,fuses the features extracted from multiple sensor signals,and establishes multiple machine learning supervised and unsupervised models.They are used to detect abnormalities in the welding process.The experimental results show that the established multiple machine learning models have high accuracy,among which the supervised learning model,the balanced accuracy of Ada boost is 0.957,and the unsupervised learning model Isolation Forest has a balanced accuracy of 0.909.
文摘We have presented an integrated approach based on supervised and unsupervised learning tech- nique to improve the accuracy of six predictive models. They are developed to predict outcome of tuberculosis treatment course and their accuracy needs to be improved as they are not precise as much as necessary. The integrated supervised and unsupervised learning method (ISULM) has been proposed as a new way to improve model accuracy. The dataset of 6450 Iranian TB patients under DOTS therapy was applied to initially select the significant predictors and then develop six predictive models using decision tree, Bayesian network, logistic regression, multilayer perceptron, radial basis function, and support vector machine algorithms. Developed models have integrated with k-mean clustering analysis to calculate more accurate predicted outcome of tuberculosis treatment course. Obtained results, then, have been evaluated to compare prediction accuracy before and after ISULM application. Recall, Precision, F-measure, and ROC area are other criteria used to assess the models validity as well as change percentage to show how different are models before and after ISULM. ISULM led to improve the prediction accuracy for all applied classifiers ranging between 4% and 10%. The most and least improvement for prediction accuracy were shown by logistic regression and support vector machine respectively. Pre-learning by k- mean clustering to relocate the objects and put similar cases in the same group can improve the classification accuracy in the process of integrating supervised and unsupervised learning.
文摘Detecting naturally arising structures in data is central to knowledge extraction from data. In most applications, the main challenge is in the choice of the appropriate model for exploring the data features. The choice is generally poorly understood and any tentative choice may be too restrictive. Growing volumes of data, disparate data sources and modelling techniques entail the need for model optimization via adaptability rather than comparability. We propose a novel two-stage algorithm to modelling continuous data consisting of an unsupervised stage whereby the algorithm searches through the data for optimal parameter values and a supervised stage that adapts the parameters for predictive modelling. The method is implemented on the sunspots data with inherently Gaussian distributional properties and assumed bi-modality. Optimal values separating high from lows cycles are obtained via multiple simulations. Early patterns for each recorded cycle reveal that the first 3 years provide a sufficient basis for predicting the peak. Multiple Support Vector Machine runs using repeatedly improved data parameters show that the approach yields greater accuracy and reliability than conventional approaches and provides a good basis for model selection. Model reliability is established via multiple simulations of this type.
文摘The purpose of this study was to explore the effects of supervised movie appreciation on improving the life meaning sense among college students. The intervention combined by “pre-video, post counseling” was conducted on the experimental group, while the control group received no intervention. Results have shown that the scores on the subscales of will to meaning, life purpose, life control, suffer acceptance and on the total scale have improved significantly. No gender difference was found on the intervention effect, and participants receiving intervention maintained higher level on related subscales a week later, indicating that supervised movie appreciation is an effective way to improve the life meaning sense among college students.
基金Project was supported by the National Key R&D Program of China(Grant No.2017YFB1104404)
文摘In order to obtain a high-quality weld during the laser welding process, extracting the characteristic parameters of weld pool is an important issue for automated welding. In this paper, the type 304 austenitic stainless steel is welded by a 5 kW high-power fiber laser and a high-speed camera is employed to capture the topside images of weld pools. Then we propose a robust visual-detection approach for the molten pool based on the supervised descent method. It provides an elegant framework for representing the outline of a weld pool and is especially efficient for weld pool detection in the presence of strong uncertainties and disturbances. Finally, welding experimental results verified that the proposed approach can extract the weld pool boundary accurately, which will lay a solid foundation for controlling the weld quality of fiber laser welding process.
文摘AIM To evaluate the effect of a 12-mo supervised aerobic and resistance training, on renal function and exercise capacity compared to usual care recommendations.METHODS Ninety-nine kidney transplant recipients(KTRs) were assigned to interventional exercise(Group A; n = 52) and a usual care cohort(Group B; n = 47). Blood and urine chemistry, exercise capacity, muscular strength, anthropometric measures and health-related quality of life(HRQo L) were assessed at baseline, and after 6 and 12 mo. Group A underwent a supervised training three times per week for 12 mo. Group B received only general recommendations about home-based physical activities.RESULTS Eighty-five KTRs completed the study(Group A, n = 44; Group B, n = 41). After 12 mo, renal function remained stable in both groups. Group A significantly increased maximum workload(+13 W, P = 0.0003), V'O2 peak(+3.1 mL/kg per minute, P = 0.0099), muscular strength in plantar flexor(+12 kg, P = 0.0368), height in the countermovement jump(+1.9 cm, P = 0.0293) and decreased in Body Mass Index(-0.5 kg/m^2, P = 0.0013). HRQo L significantly improved in physical function(P = 0.0019), physical-role limitations(P = 0.0321) and social functioning scales(P = 0.0346). Noimprovements were found in Group B.CONCLUSION Twelve-month of supervised aerobic and resistance training improves the physiological variables related to physical fitness and cardiovascular risks without consequences on renal function. Recommendations alone are not sufficient to induce changes in exercise capacity of KTRs. Our study is an example of collaborative working between transplant centres, sports medicine and exercise facilities.
基金supported in part by the National Key R&D Program of China(2017YFB0502904)the National Science Foundation of China(61876140)。
文摘Recently,video object segmentation has received great attention in the computer vision community.Most of the existing methods heavily rely on the pixel-wise human annotations,which are expensive and time-consuming to obtain.To tackle this problem,we make an early attempt to achieve video object segmentation with scribble-level supervision,which can alleviate large amounts of human labor for collecting the manual annotation.However,using conventional network architectures and learning objective functions under this scenario cannot work well as the supervision information is highly sparse and incomplete.To address this issue,this paper introduces two novel elements to learn the video object segmentation model.The first one is the scribble attention module,which captures more accurate context information and learns an effective attention map to enhance the contrast between foreground and background.The other one is the scribble-supervised loss,which can optimize the unlabeled pixels and dynamically correct inaccurate segmented areas during the training stage.To evaluate the proposed method,we implement experiments on two video object segmentation benchmark datasets,You Tube-video object segmentation(VOS),and densely annotated video segmentation(DAVIS)-2017.We first generate the scribble annotations from the original per-pixel annotations.Then,we train our model and compare its test performance with the baseline models and other existing works.Extensive experiments demonstrate that the proposed method can work effectively and approach to the methods requiring the dense per-pixel annotations.
基金partially funded by the National Natural Science Foundation of China (Grants 51520105005 and U1663208)
文摘This study proposes a supervised learning method that does not rely on labels.We use variables associated with the label as indirect labels,and construct an indirect physics-constrained loss based on the physical mechanism to train the model.In the training process,the model prediction is mapped to the space of value that conforms to the physical mechanism through the projection matrix,and then the model is trained based on the indirect labels.The final prediction result of the model conforms to the physical mechanism between indirect label and label,and also meets the constraints of the indirect label.The present study also develops projection matrix normalization and prediction covariance analysis to ensure that the model can be fully trained.Finally,the effect of the physics-constrained indirect supervised learning is verified based on a well log generation problem.
基金supported by Chiang Mai University Research Fund under the contract number T-M5744
文摘A method that applies clustering technique to reduce the number of samples of large data sets using input-output clustering is proposed.The proposed method clusters the output data into groups and clusters the input data in accordance with the groups of output data.Then,a set of prototypes are selected from the clustered input data.The inessential data can be ultimately discarded from the data set.The proposed method can reduce the effect from outliers because only the prototypes are used.This method is applied to reduce the data set in regression problems.Two standard synthetic data sets and three standard real-world data sets are used for evaluation.The root-mean-square errors are compared from support vector regression models trained with the original data sets and the corresponding instance-reduced data sets.From the experiments,the proposed method provides good results on the reduction and the reconstruction of the standard synthetic and real-world data sets.The numbers of instances of the synthetic data sets are decreased by 25%-69%.The reduction rates for the real-world data sets of the automobile miles per gallon and the 1990 census in CA are 46% and 57%,respectively.The reduction rate of 96% is very good for the electrocardiogram(ECG) data set because of the redundant and periodic nature of ECG signals.For all of the data sets,the regression results are similar to those from the corresponding original data sets.Therefore,the regression performance of the proposed method is good while only a fraction of the data is needed in the training process.
文摘The motivation for this article is to propose new damage classifiers based on a supervised learning problem for locating and quantifying damage.A new feature extraction approach using time series analysis is introduced to extract damage-sensitive features from auto-regressive models.This approach sets out to improve current feature extraction techniques in the context of time series modeling.The coefficients and residuals of the AR model obtained from the proposed approach are selected as the main features and are applied to the proposed supervised learning classifiers that are categorized as coefficient-based and residual-based classifiers.These classifiers compute the relative errors in the extracted features between the undamaged and damaged states.Eventually,the abilities of the proposed methods to localize and quantify single and multiple damage scenarios are verified by applying experimental data for a laboratory frame and a four-story steel structure.Comparative analyses are performed to validate the superiority of the proposed methods over some existing techniques.Results show that the proposed classifiers,with the aid of extracted features from the proposed feature extraction approach,are able to locate and quantify damage;however,the residual-based classifiers yield better results than the coefficient-based classifiers.Moreover,these methods are superior to some classical techniques.
