The widespread interest in layered P2-type Mn-based cathode materials for sodium-ion batteries(SIBs)stems from their cost-effectiveness and abundant resources.However,the inferior cycle stability and mediocre rate per...The widespread interest in layered P2-type Mn-based cathode materials for sodium-ion batteries(SIBs)stems from their cost-effectiveness and abundant resources.However,the inferior cycle stability and mediocre rate performance impede their further development in practical applications.Herein,we devised a wet chemical precipitation method to deposit an amorphous aluminum phosphate(AlPO_(4),denoted as AP)protective layer onto the surface of P2-type Na_(0.55)Ni_(0.1)Co_(0.7)Mn_(0.8)O_(2)(NCM@AP).The resulting NCM@5AP electrode,with a 5 wt%coating,exhibits extended cycle life(capacity retention of78.4%after 200 cycles at 100 mA g^(-1))and superior rate performance(98 mA h g^(-1)at 500 mA g^(-1))compared to pristine NCM.Moreover,our investigation provides comprehensive insights into the phase stability and active Na^(+)ion kinetics in the NCM@5AP composite electrode,shedding light on the underlying mechanisms responsible for the enhanced performance observed in the coated electrode.展开更多
Electrochemical carbon dioxide reduction reaction(CO_(2)RR)provides a promising way to convert CO_(2)to chemicals.The multicarbon(C_(2+))products,especially ethylene,are of great interest due to their versatile indust...Electrochemical carbon dioxide reduction reaction(CO_(2)RR)provides a promising way to convert CO_(2)to chemicals.The multicarbon(C_(2+))products,especially ethylene,are of great interest due to their versatile industrial applications.However,selectively reducing CO_(2)to ethylene is still challenging as the additional energy required for the C–C coupling step results in large overpotential and many competing products.Nonetheless,mechanistic understanding of the key steps and preferred reaction pathways/conditions,as well as rational design of novel catalysts for ethylene production have been regarded as promising approaches to achieving the highly efficient and selective CO_(2)RR.In this review,we first illustrate the key steps for CO_(2)RR to ethylene(e.g.,CO_(2)adsorption/activation,formation of~*CO intermediate,C–C coupling step),offering mechanistic understanding of CO_(2)RR conversion to ethylene.Then the alternative reaction pathways and conditions for the formation of ethylene and competitive products(C_1 and other C_(2+)products)are investigated,guiding the further design and development of preferred conditions for ethylene generation.Engineering strategies of Cu-based catalysts for CO_(2)RR-ethylene are further summarized,and the correlations of reaction mechanism/pathways,engineering strategies and selectivity are elaborated.Finally,major challenges and perspectives in the research area of CO_(2)RR are proposed for future development and practical applications.展开更多
The sluggish kinetics of multiphase sulfur conversion with homogeneous and heterogeneous electrochemical processes,causing the“shuttle effect”of soluble polysulfide species(PSs),is the challenges in terms of lithium...The sluggish kinetics of multiphase sulfur conversion with homogeneous and heterogeneous electrochemical processes,causing the“shuttle effect”of soluble polysulfide species(PSs),is the challenges in terms of lithium-sulfur batteries(LSBs).In this paper,a Mn_(3)O_(4-x) catalyst,which has much higher activity for heterogeneous reactions than for homogeneous reactions(namely,preferentialactivity catalysts),is designed by surface engineering with rational oxygen vacancies.Due to the rational design of the electronic structure,the Mn_(3)O_(4-x) catalyst prefers to accelerate the conversion of Li2S4 into Li_(2)S_(2)/Li_(2)S and optimize Li_(2)S deposition,reducing the accumulation of PSs and thus suppressing the“shuttle effect.”Both density functional theory calculations and in situ X-ray diffraction measurements are used to probe the catalytic mechanism and identify the reaction intermediates of MnS and Li_(y)Mn_(z)O_(4-x) for fundamental understanding.The cell with Mn_(3)O_(4-x) delivers an ultralow attenuation rate of 0.028% per cycle over 2000 cycles at 2.5 C.Even with sulfur loadings of 4.93 and 7.10mg cm^(-2) in a lean electrolyte(8.4μL mg s^(-1)),the cell still shows an initial areal capacity of 7.3mAh cm^(-2).This study may provide a new way to develop preferential-activity heterogeneous-reaction catalysts to suppress the“shuttle effect”of the soluble PSs generated during the redox process of LSBs.展开更多
The surface properties of catalysts determine the intrinsic activity and adaptability.Ruthenium is regarded as a potential candidate to substitute platinum for water electrolysis due to the low cost and analogous elec...The surface properties of catalysts determine the intrinsic activity and adaptability.Ruthenium is regarded as a potential candidate to substitute platinum for water electrolysis due to the low cost and analogous electronic structures while it suffers from severe dissolution and stability problems.Herein,the modification of Ru/C with atomically dispersed cobalt atoms is achieved via a simple thermal doping method.The newly formed amorphous shell with Ru-Co sites on the Ru/C catalyst improved the hydrogen evolution reaction activity and stability significantly.Impressively,the obtained Co1Ru@Ru/CN_(x)catalyst exhibited an overpotential as low as 30 mV at 10 mA cm^(-2)in an alkaline medium,which is among the best HER catalysts reported so far.The oxygen oxophile Co prevents the fast oxidation and dissolution of Ru species,ensuring outstanding long-term durability up to 70 h.Theoretical calculations reveal that the Ru-Co coordination acts as a more active site for water dissociation than the Ru-Ru.Meanwhile,the"Ru-Co shell/Ru core"structures show high adaptability for the reaction conditions.This simple doping strategy offers prospects for scalable preparation of highly active electrocatalysts.展开更多
Lithium-sulfur(Li-S)batteries have been recognized as one of the most promising candidates for nextgeneration portable electronic devices,owing to their extremely high energy density and low cost.However,the dissoluti...Lithium-sulfur(Li-S)batteries have been recognized as one of the most promising candidates for nextgeneration portable electronic devices,owing to their extremely high energy density and low cost.However,the dissolution of lithium polysulfides(LiPSs)and consequent"shuttle effect"seriously hinder the practical deployment of Li-S batteries.Herein,multi-metal oxide nanorods named attapulgite are proposed as multifunctional ionic sieve to immobilize LiPSs and further promote the regulation of LiPSs.Attapulgite,consisting of Al,Mg,Fe,Si and O ions,possesses more polar sites to immobilize LiPSs in comparison with single metal oxides.In addition,the catalytic nature(Fe ions)of attapulgite avails the LiPSs conversion reaction,which is further confirmed by the linear sweep voltammetry and electrochemical impedance spectroscopy.Benefited from the synergistic effect of multi-metal oxide and conductive carbon,the Li-S battery with the modified separator delivers remarkable discharge capacities of 1059.4 mAh g-1 and 792.5 mAh g-1 for the first and 200th cycle at 0.5 C,respectively.The work presents an effective way to improve the electrochemical performance of Li-S batteries by employing attapulgite nanorods assisted separator surface engineering.展开更多
Photocatalytic conversion of CO_(2)into solar fuels provides a bright route for the green and sustainable development of human society.However,the realization of efficient photocatalytic CO_(2)reduction reaction(CO_(2...Photocatalytic conversion of CO_(2)into solar fuels provides a bright route for the green and sustainable development of human society.However,the realization of efficient photocatalytic CO_(2)reduction reaction(CO_(2)RR)is still challenging owing to the sluggish kinetics or unfavorable thermodynamics for basic chemical processes of CO_(2)RR,such as adsorption,activation,conversion and product desorption.To overcome these shortcomings,recent works have demonstrated that surface engineering of semiconductors,such as introducing surface vacancy,surface doping,and cocatalyst loading,serves as effective or promising strategies for improved photocatalytic CO_(2)RR with high activity and selectivity.The essential reason lies in the activation and reaction pathways can be optimized and regulated through the reconstruction of surface atomic and electronic structures.Herein,in this review,we focus on recent research advances about rational design of semiconductor surface for photocatalytic CO_(2)RR.The surface engineering strategies for improved CO_(2)adsorption,activation,and product selectivity will be reviewed.In addition,theoretical calculations along with in situ characterization techniques will be in the spotlight to clarify the kinetics and thermodynamics of the reaction process.The aim of this review is to provide deep understanding and rational guidance on the design of semiconductors for photocatalytic CO_(2)RR.展开更多
Solid oxide cells(SOCs)have attracted great attention in the past decades because of their high conversion efficiency,low environmental pollution and diversified fuel options.Nickel-based catalysts are the most widely...Solid oxide cells(SOCs)have attracted great attention in the past decades because of their high conversion efficiency,low environmental pollution and diversified fuel options.Nickel-based catalysts are the most widely used fuel electrode materials for SOCs due to the low price and high activity.However,when hydrocarbon fuels are employed,nickel-based electrodes face serious carbon deposition challenges,leading to a rapid decline of cell performance.Great efforts have been devoted to understanding the occurrence of the coking reaction,and to improving the stability of the electrodes in hydrocarbon fuels.In this review,we summarize recent research progress of utilizing surface modification to improve the stability and activity of Ni-based electrodes for SOCs by preventing carbon coking.The review starts with a briefly introduction about the reaction mechanism of carbon deposition,followed by listing several surface modification technologies and their working principles.Then we introduce representative works using surface modification strategies to prevent carbon coking on Ni-based electrodes.Finally,we highlight future direction of improving electrode catalytic activity and anti-coking performance through surface engineering.展开更多
As system of a serial of technologies and engineering activities, remanufacturing aims at restoring and rebuilding waste machinery through advanced technologies and industrialized measures under the direction of the p...As system of a serial of technologies and engineering activities, remanufacturing aims at restoring and rebuilding waste machinery through advanced technologies and industrialized measures under the direction of the product total life cycle theory. With the development of surface engineering, nano-surface engineering has been one subject of intensive studies. In addition, nano-surface engineering has become an important means for property reforming and promoting of remanufacturing parts. Many low-dimension and nano-size or nano-structure functional coatings, which can improve materials properties evidently, are deposited by new methods. In this paper, some researches about the new achievement and remanufacturing application of the nano-stmctured coatings by different nano-surface engineering technologies in our laboratory were introduced. Especially, nano-structured DLC multilayer coatings by d.c. plasma CVD, nano-composed Al2O3/Ni, SiC/Ni and Diamond/Ni coatings by brush plating, and nano-composed Al2O3/TiO2 coating by plasma spraying were introduced in detail.展开更多
Peculiar hierarchical microstructures in creatures inspire modern material design with distinct functionalities.Creatures can effortlessly construct sophisticated yet long-range ordered microstructure across bio-membr...Peculiar hierarchical microstructures in creatures inspire modern material design with distinct functionalities.Creatures can effortlessly construct sophisticated yet long-range ordered microstructure across bio-membrane through ion secretion and precipitation.However,microstructure biomimicry in current technology generally requires elaborate,point-by-point fabrication.Herein,a spontaneous yet controllable strategy is developed to achieve surface microstructure engineering through a natural surface phenomenon similar to ion secretion-precipitation,that is,coupled dissolution-precipitation.A series of hierarchical microstructures on mineral surfaces in fluids with tunable morphology,orientation,dimension,and spatial distribution are achieved by simply controlling initial dissolution and fluid chemistry.In seawater,long-range ordered film of vertically aligned brucite flakes forms through interfacial dissolution,nucleation,and confinement-induced orientation of flakes with vertically grown{110}plane,on the edge of which,fusiform aragonite epitaxially precipitates.With negligible initial surface dissolution,prismatic aragonite epitaxially grows on a calcite polyhedron-packed surface.By tuning fluid chemistry,closely packed calcite polyhedron and loosely packed calcite micro-pillars are engineered through rapid and retarded precipitation,respectively.Surprisingly,the spontaneously grown microstructures resemble those deliberately created by human or found in nature,and tremendously modulate surface functionality.These findings open new possibilities for facile and customizable engineering of microstructural surfaces,hierarchical heterostructures,and biomimetic materials.展开更多
Surface engineering,which modulates the electronic structure and adsorption/desorption properties of electrocatalysts,is one of the key strategies for improving the catalytic performance.Herein,we demonstrate a facile...Surface engineering,which modulates the electronic structure and adsorption/desorption properties of electrocatalysts,is one of the key strategies for improving the catalytic performance.Herein,we demonstrate a facile solid-phase reaction for surface engineering of MnO_(2)to boost the oxygen reduction kinetics.Via reaction with surface hydroxy groups,La single atoms with loading amount up to 2.7 wt%are anchored onto a-MnO_(2)nanorods.After surface engineering,the oxygen reduction reaction(ORR)kinetics is significantly improved with the half-wave potential from 0.70 to 0.84 V,the number of transferred electrons from 2.5 to 3.9 and the limiting current density from 4.8 to 6.0 mA·cm^(-2).In addition,the catalyst delivers superior discharge performance in both alkaline and neutral metal–air batteries.Density functional theory(DFT)calculations reveal that atomic La modulates the surface electronic configuration of MnO_(2),reduces its d-band center and thus lowers the OOH*and O*reaction energy barrier.This work provides a new route for rational design of highly active electrocatalyst and holds great potential for application in various catalytic reactions.展开更多
Electrolytic water splitting by renewable energy is a technology with great potential for producing hydrogen(H_(2))without carbon emission,but this technical route is hindered by its huge energy(electricity)cost,which...Electrolytic water splitting by renewable energy is a technology with great potential for producing hydrogen(H_(2))without carbon emission,but this technical route is hindered by its huge energy(electricity)cost,which is mainly wasted by the anode oxygen evolution reaction(OER)while the value of the anode product(oxygen)is very limited.Replacing the high-energy-cost OER with a selective organic compound electrooxidation carried out at a relatively lower potential can reduce the electricity cost while producing value-added chemicals.Currently,H_(2) generation coupled with synthesis of value-added organic compounds faces the challenge of low selectivity and slow generation rate of the anodic products.One-dimensional(1D)nanocatalysts with a unique morphology,well-defined active sites,and good electron conductivity have shown excellent performance in many electrocatalytic reactions.The rational design and regulation of 1D nanocatalysts through surface engineering can optimize the adsorption energy of intermediate molecules and improve the selectivity of organic electrooxidation reactions.Herein,we summarized the recent research progress of 1D nanocatalysts applied in different organic electrooxidation reactions and introduced several different fabrication strategies for surface engineering of 1D nanocatalysts.Then,we focused on the relationship between surface engineering and the selectivity of organic electrooxidation reaction products.Finally,future challenges and development prospects of 1D nanocatalysts in the coupled system consisting of organic electrooxidation and hydrogen evolution reactions are briefly outlined.展开更多
Removal of boric acid from seawater and wastewater using reverse osmosis membrane technologies is imperative and yet remains inadequately addressed by current commercial membranes.Existing research efforts performed p...Removal of boric acid from seawater and wastewater using reverse osmosis membrane technologies is imperative and yet remains inadequately addressed by current commercial membranes.Existing research efforts performed post-modification of reverse osmosis membranes to enhance boron rejection,which is usually accompanied by substantial sacrifice in water permeability.This study delves into the surface engineering of low-pressure reverse osmosis membranes,aiming to elevate boron removal efficiency while maintaining optimal salt rejection and water permeability.Membranes were modified by the self-polymerization and co-deposition of dopamine and polystyrene sulfonate at varying ratios and concentrations.The surfaces became smoother and more hydrophilic after modification.The optimum membrane exhibited a water permeability of 9.2±0.1 L·m^(-2)·h^(-1)·bar^(-1),NaCl rejection of 95.8%±0.3%,and boron rejection of 49.7%±0.1% and 99.6%±0.3% at neutral and alkaline pH,respectively.The water permeability is reduced by less than 15%,while the boron rejection is 3.7 times higher compared to the blank membrane.This research provides a promising avenue for enhancing boron removal in reverse osmosis membranes and addressing water quality concerns in the desalination process.展开更多
Lithium-rich manganese-based oxides(LRMOs) exhibit high theoretical energy densities, making them a prominent class of cathode materials for lithium-ion batteries. However, the performance of these layered cathodes of...Lithium-rich manganese-based oxides(LRMOs) exhibit high theoretical energy densities, making them a prominent class of cathode materials for lithium-ion batteries. However, the performance of these layered cathodes often declines because of capacity fading during cycling. This decline is primarily attributed to anisotropic lattice strain and oxygen release from cathode surfaces. Given notable structural transformations, complex redox reactions, and detrimental interface side reactions in LRMOs, the development of a single modification approach that addresses bulk and surface issues is challenging. Therefore,this study introduces a surface double-coupling engineering strategy that mitigates bulk strain and reduces surface side reactions. The internal spinel-like phase coating layer, featuring threedimensional(3D) lithium-ion diffusion channels, effectively blocks oxygen release from the cathode surface and mitigates lattice strain. In addition, the external Li_(3)PO_(4) coating layer, noted for its superior corrosion resistance, enhances the interfacial lithium transport and inhibits the dissolution of surface transition metals. Notably, the spinel phase, as excellent interlayer, securely anchors Li_(3)PO_(4) to the bulk lattice and suppresses oxygen release from lattices. Consequently, these modifications considerably boost structural stability and durability, achieving an impressive capacity retention of 83.4% and a minimal voltage decay of 1.49 m V per cycle after 150 cycles at 1 C. These findings provide crucial mechanistic insights into the role of surface modifications and guide the development of high-capacity cathodes with enhanced cyclability.展开更多
Biocatalysis in organic solvents(OSs)has numerous important applications,but native enzymes in OSs often exhibit limited catalytic performance.Herein,we proposed a computation-aided surface charge engineering strategy...Biocatalysis in organic solvents(OSs)has numerous important applications,but native enzymes in OSs often exhibit limited catalytic performance.Herein,we proposed a computation-aided surface charge engineering strategy to improve the catalytic performance of haloalkane dehalogenase DhaA in OSs based on the energetic analysis of substrate binding to the DhaA surface.Several variants with enhanced OS resistance were obtained by replacing negative charged residues on the surface with positive charged residue(Arg).Particularly,a four-substitution variant E16R/E93R/E121R/E257R exhibited the best catalytic performance(five-fold improvement in OS resistance and seven-fold half-life increase in 40%(vol)dimethylsulfoxide).As a result,the overall catalytic performance of the variant could be at least 26 times higher than the wild-type DhaA.Fluorescence spectroscopy and molecular dynamics simulation studies revealed that the residue substitution mainly enhanced OS resistance from four aspects:(a)improved the overall structural stability,(b)increased the hydrophobicity of the local microenvironment around the catalytic triad,(c)enriched the hydrophobic substrate around the enzyme molecule,and(d)lowered the contact frequency between OS molecules and the catalytic triad.Our findings validate that computationaided surface charge engineering is an effective and ingenious rational strategy for tailoring enzyme performance in OSs.展开更多
Layered oxide cathodes with high Ni content promise high energy density and competitive cost for Li-ion batteries(LIBs).However,Ni-rich cathodes suffer from irreversible interface reconstruction and undesirable cracki...Layered oxide cathodes with high Ni content promise high energy density and competitive cost for Li-ion batteries(LIBs).However,Ni-rich cathodes suffer from irreversible interface reconstruction and undesirable cracking with severe performance degradation upon long-term operation,especially at elevated temperatures.Herein,we demonstrate in situ surface engineering of Ni-rich cathodes to construct a dual ion/electron-conductive NiTiO 3 coating layer and Ti gradient doping(NC90–Ti@NTO)in parallel.The dual-modification synergy helps to build a thin,robust cathode–electrolyte interface with rapid Li-ion transport and enhanced reaction kinetics,and effec-tively prevents unfavorable crystalline phase transformation during long-term cycling under harsh environments.The optimized NC90–Ti@NTO delivers a high reversible capacity of 221.0 mAh g^(-1) at 0.1C and 158.9 mAh g^(-1) at 10C.Impressively,it exhibits a capacity retention of 88.4%at 25?C after 500 cycles and 90.7%at 55?C after 300 cycles in a pouch-type full battery.This finding provides viable clues for stabilizing the lattice and interfacial chemistry of Ni-rich cathodes to achieve durable LIBs with high energy density.展开更多
Opportunities coexist with challenges for the development of carbon-based cathodes with a high energy density applied for zinc ion hybrid capacitors(ZIHCs).In the present study,a facile and effective surface engineeri...Opportunities coexist with challenges for the development of carbon-based cathodes with a high energy density applied for zinc ion hybrid capacitors(ZIHCs).In the present study,a facile and effective surface engineering approach is demonstrated to greatly improve the energy storage ability of commercial carbon paper(CP)in ZIHC.Benefiting from the introduced oxygen functional groups,larger surface area and improved surface wettability upon air calcination,the assembled aqueous ZIHC with the functionalized carbon paper(FCP)exhibits a much higher areal capacity of 0.22 mAh/cm^(2)at 1 mA/cm^(2),outperforming the counterpart with blank CP by over 5000 times.More importantly,a superior energy density and power density of 130.8μWh/cm^(2)and 7460.5μW/cm^(2),are respectively delivered.Furthermore,more than 90%of the initial capacity is retained over 10000 cycles.This surface engineering strategy to improve the energy storage capability is potentially applicable to developing a wide range of high-energy carbon electrode materials.展开更多
Nanosilver has been regarded as a promising alternative to traditional antibiotics for fighting pathogenassociated infections due to its efficacy toward a broad spectrum of pathogens.However,bacterial resistance to na...Nanosilver has been regarded as a promising alternative to traditional antibiotics for fighting pathogenassociated infections due to its efficacy toward a broad spectrum of pathogens.However,bacterial resistance to nanosilver has emerged recently.In this contribution,a surface engineering strategy based on N-halamine chemistry to address bacterial resistance to nanosilver was proposed.Using 1,3-dichloro-5,5-dimethylhydantoin(DCDMH)as an N-halamine source,AgCI nanodots were deposited on the surface of Ag nano wires(Ag NWs)via in situ redox reaction to prepare AgCl-on-Ag NWs.After in vitro and in vivo tests,AgCl-on-Ag NWs effectively inactivated two antibiotic-resistant bacteria,ampicillinresistant Escherichia coli(AREC)and methicillin-resistant Staphylococcus aureus(MRSA)with the minimum bactericidal concentration(MBC)as low as 10μg·ml~(-1)and exhibited good biosafety against normal cells.The experimental and theoretical tests demonstrated that AgCl-onAg NWs worked on AREC and MAS A by generating high level of reactive oxygen species under visible light irradiation,coupled with the sustained Ag ion release.Meanwhile,the antibacterial mechanism of AgCl-on-Ag NWs against MRSA was verified at the gene level by transcriptome analysis(RNA sequencing).Moreover,the fullthickness defect model verified that AgCl-on-Ag NWs reduced inflammatory cell infiltration and dramatically accelerated wound healing.This work provides a synergistic mechanism based on nanosilver surface engineering to eradicate the resistant bacteria that can alleviate drug resistance and develop an innovative approach for the treatment of bacterial infections.展开更多
Late in-stent thrombus and restenosis still represent two major challenges in stents’design.Surface treatment of stent is attracting attention due to the increasing importance of stenting intervention for coronary ar...Late in-stent thrombus and restenosis still represent two major challenges in stents’design.Surface treatment of stent is attracting attention due to the increasing importance of stenting intervention for coronary artery diseases.Several surface engineering techniques have been utilised to improve the biological response in vivo on a wide range of biomedical devices.As a tailorable,precise,and ultra-fast process,laser surface engineering offers the potential to treat stent materials and fabricate various 3D textures,including grooves,pillars,nanowires,porous and freeform structures,while also modifying surface chemistry through nitridation,oxidation and coatings.Laser-based processes can reduce the biodegradable materials’degradation rate,offering many advantages to improve stents’performance,such as increased endothelialisation rate,prohibition of SMC proliferation,reduced platelet adhesion and controlled corrosion and degradation.Nowadays,adequate research has been conducted on laser surface texturing and surface chemistry modification.Laser texturing on commercial stents has been also investigated and a promotion of performance of laser-textured stents has been proved.In this critical review,the influence of surface texture and surface chemistry on stents performance is firstly reviewed to understand the surface characteristics of stents required to facilitate cellular response.This is followed by the explicit illustration of laser surface engineering of stents and/or related materials.Laser induced periodic surface structure(LIPSS)on stent materials is then explored,and finally the application of laser surface modification techniques on latest generation of stent devices is highlighted to provide future trends and research direction on laser surface engineering of stents.展开更多
Biomimetic nanoengineering presents great potential in biomedical research by integrating cell membrane(CM) with functional nanoparticles. However, preparation of CM biomimetic nanomaterials for custom applications th...Biomimetic nanoengineering presents great potential in biomedical research by integrating cell membrane(CM) with functional nanoparticles. However, preparation of CM biomimetic nanomaterials for custom applications that can avoid the aggregation of nanocarriers while maintaining the biological activity of CM remains a challenge. Herein, a high-performance CM biomimetic graphene nanodecoy was fabricated via purposeful surface engineering, where polyethylene glycol(PEG) was used to modifying magnetic graphene oxide(MGO) to improve its stability in physiological solution, so as to improve the screening efficiency to active components of traditional Chinese medicine(TCM). With this strategy, the constructed PEGylated MGO(PMGO) could keep stable at least 10 days, thus improving the CM coating efficiency. Meanwhile, by taking advantage of the inherent ability of He La cell membrane(HM) to interact with specific ligands, HM-camouflaged PMGO showed satisfied adsorption capacity(116.2 mg/g) and selectivity. Finally, three potential active components, byakangelicol, imperatorin,and isoimperatorin, were screened from Angelica dahurica, whose potential antiproliferative activity were further validated by pharmacological studies. These results demonstrated that the purposeful surfaceengineering is a promising strategy for the design of efficient CM biomimetic nanomaterials, which will promote the development of active components screening in TCM.展开更多
In the past decade, nanopores have been developed extensively for various potential applications, and their performance greatly depends on the surface properties of the nanopores. Atomic layer deposition （ALD） is a ...In the past decade, nanopores have been developed extensively for various potential applications, and their performance greatly depends on the surface properties of the nanopores. Atomic layer deposition （ALD） is a new technology for depositing thin films, which has been rapidly developed from a niche technology to an established method. ALD films can cover the surface in confined regions even in nanoscale conformally, thus it is proved to be a powerful tool to modify the surface of the synthetic nanopores and also to fabricate complex nanopores. This review gives a brief introduction on nanopore synthesis and ALD fundamental knowledge, and then focuses on the various aspects of synthetic nanopores processing by ALD and their applications, including single-molecule sensing, nanofiuidic devices, nanostructure fabrication and other applications.展开更多
基金financially supported by the Australian Research Council(ARC) through the Future Fellowship(FT180100705)the financial support from China Scholarship Council+3 种基金the support from UTS-HUST Key Technology Partner Seed Fundthe support from Open Project of State Key Laboratory of Advanced Special Steel,the Shanghai Key Laboratory of Advanced Ferrometallurgy,Shanghai University(SKLASS 2021-04)the Science and Technology Commission of Shanghai Municipality(22010500400)“Joint International Laboratory on Environmental and Energy Frontier Materials”and“Innovation Research Team of High–Level Local Universities in Shanghai”in Shanghai University。
文摘The widespread interest in layered P2-type Mn-based cathode materials for sodium-ion batteries(SIBs)stems from their cost-effectiveness and abundant resources.However,the inferior cycle stability and mediocre rate performance impede their further development in practical applications.Herein,we devised a wet chemical precipitation method to deposit an amorphous aluminum phosphate(AlPO_(4),denoted as AP)protective layer onto the surface of P2-type Na_(0.55)Ni_(0.1)Co_(0.7)Mn_(0.8)O_(2)(NCM@AP).The resulting NCM@5AP electrode,with a 5 wt%coating,exhibits extended cycle life(capacity retention of78.4%after 200 cycles at 100 mA g^(-1))and superior rate performance(98 mA h g^(-1)at 500 mA g^(-1))compared to pristine NCM.Moreover,our investigation provides comprehensive insights into the phase stability and active Na^(+)ion kinetics in the NCM@5AP composite electrode,shedding light on the underlying mechanisms responsible for the enhanced performance observed in the coated electrode.
基金financially supported via Australian Research Council(FT180100705)the support by the National Natural Science Foundation of China(22209103)+3 种基金the support from UTS Chancellor's Research Fellowshipsthe support from Open Project of State Key Laboratory of Advanced Special Steel,the Shanghai Key Laboratory of Advanced Ferrometallurgy,Shanghai University(SKLASS 2021-**)Joint International Laboratory on Environmental and Energy Frontier MaterialsInnovation Research Team of High-Level Local Universities in Shanghai。
文摘Electrochemical carbon dioxide reduction reaction(CO_(2)RR)provides a promising way to convert CO_(2)to chemicals.The multicarbon(C_(2+))products,especially ethylene,are of great interest due to their versatile industrial applications.However,selectively reducing CO_(2)to ethylene is still challenging as the additional energy required for the C–C coupling step results in large overpotential and many competing products.Nonetheless,mechanistic understanding of the key steps and preferred reaction pathways/conditions,as well as rational design of novel catalysts for ethylene production have been regarded as promising approaches to achieving the highly efficient and selective CO_(2)RR.In this review,we first illustrate the key steps for CO_(2)RR to ethylene(e.g.,CO_(2)adsorption/activation,formation of~*CO intermediate,C–C coupling step),offering mechanistic understanding of CO_(2)RR conversion to ethylene.Then the alternative reaction pathways and conditions for the formation of ethylene and competitive products(C_1 and other C_(2+)products)are investigated,guiding the further design and development of preferred conditions for ethylene generation.Engineering strategies of Cu-based catalysts for CO_(2)RR-ethylene are further summarized,and the correlations of reaction mechanism/pathways,engineering strategies and selectivity are elaborated.Finally,major challenges and perspectives in the research area of CO_(2)RR are proposed for future development and practical applications.
基金National Nature Science Foundation of China,Grant/Award Number:21908124。
文摘The sluggish kinetics of multiphase sulfur conversion with homogeneous and heterogeneous electrochemical processes,causing the“shuttle effect”of soluble polysulfide species(PSs),is the challenges in terms of lithium-sulfur batteries(LSBs).In this paper,a Mn_(3)O_(4-x) catalyst,which has much higher activity for heterogeneous reactions than for homogeneous reactions(namely,preferentialactivity catalysts),is designed by surface engineering with rational oxygen vacancies.Due to the rational design of the electronic structure,the Mn_(3)O_(4-x) catalyst prefers to accelerate the conversion of Li2S4 into Li_(2)S_(2)/Li_(2)S and optimize Li_(2)S deposition,reducing the accumulation of PSs and thus suppressing the“shuttle effect.”Both density functional theory calculations and in situ X-ray diffraction measurements are used to probe the catalytic mechanism and identify the reaction intermediates of MnS and Li_(y)Mn_(z)O_(4-x) for fundamental understanding.The cell with Mn_(3)O_(4-x) delivers an ultralow attenuation rate of 0.028% per cycle over 2000 cycles at 2.5 C.Even with sulfur loadings of 4.93 and 7.10mg cm^(-2) in a lean electrolyte(8.4μL mg s^(-1)),the cell still shows an initial areal capacity of 7.3mAh cm^(-2).This study may provide a new way to develop preferential-activity heterogeneous-reaction catalysts to suppress the“shuttle effect”of the soluble PSs generated during the redox process of LSBs.
基金support from the National Natural Science Foundation of China(21802120,21872121,and 21908189)the National Key R&D Program of China(2016YFA0202900)+3 种基金the Key R&D Project of Zhejiang Province(2020C01133)the Fundamental Research Funds for the Central Universities(G2019KY05119)the China Postdoctoral Science Foundation(2021 M692634)the Natural Science Basic Research Program of Shaanxi Province(2022JQ-118)are greatly appreciated.
文摘The surface properties of catalysts determine the intrinsic activity and adaptability.Ruthenium is regarded as a potential candidate to substitute platinum for water electrolysis due to the low cost and analogous electronic structures while it suffers from severe dissolution and stability problems.Herein,the modification of Ru/C with atomically dispersed cobalt atoms is achieved via a simple thermal doping method.The newly formed amorphous shell with Ru-Co sites on the Ru/C catalyst improved the hydrogen evolution reaction activity and stability significantly.Impressively,the obtained Co1Ru@Ru/CN_(x)catalyst exhibited an overpotential as low as 30 mV at 10 mA cm^(-2)in an alkaline medium,which is among the best HER catalysts reported so far.The oxygen oxophile Co prevents the fast oxidation and dissolution of Ru species,ensuring outstanding long-term durability up to 70 h.Theoretical calculations reveal that the Ru-Co coordination acts as a more active site for water dissociation than the Ru-Ru.Meanwhile,the"Ru-Co shell/Ru core"structures show high adaptability for the reaction conditions.This simple doping strategy offers prospects for scalable preparation of highly active electrocatalysts.
基金supported by the National Natural Science Foundation of China(Nos.51861165101,51822706,51777200)Beijing Natural Science Foundation(No.JQ19012)DNL Cooperation Fund,CAS(DNL201912)。
文摘Lithium-sulfur(Li-S)batteries have been recognized as one of the most promising candidates for nextgeneration portable electronic devices,owing to their extremely high energy density and low cost.However,the dissolution of lithium polysulfides(LiPSs)and consequent"shuttle effect"seriously hinder the practical deployment of Li-S batteries.Herein,multi-metal oxide nanorods named attapulgite are proposed as multifunctional ionic sieve to immobilize LiPSs and further promote the regulation of LiPSs.Attapulgite,consisting of Al,Mg,Fe,Si and O ions,possesses more polar sites to immobilize LiPSs in comparison with single metal oxides.In addition,the catalytic nature(Fe ions)of attapulgite avails the LiPSs conversion reaction,which is further confirmed by the linear sweep voltammetry and electrochemical impedance spectroscopy.Benefited from the synergistic effect of multi-metal oxide and conductive carbon,the Li-S battery with the modified separator delivers remarkable discharge capacities of 1059.4 mAh g-1 and 792.5 mAh g-1 for the first and 200th cycle at 0.5 C,respectively.The work presents an effective way to improve the electrochemical performance of Li-S batteries by employing attapulgite nanorods assisted separator surface engineering.
基金financially supported by JSPS KAKENHI(JP18H02065)Photo-excitonic Project in Hokkaido University,National Natural Science Foundation of China(21633004,22002060,and 51872138)+4 种基金Natural Science Foundation of Jiangsu Province(BK20181380)Qing Lan Project,Six Talent Peaks Project in Jiangsu Province(XCL-029)Priority Academic Program Development of the Jiangsu Higher Education Institutions(PAPD)the support provided by the China Scholarships Council(202008320109)China Postdoctoral Science Foundation(2020M681564)。
文摘Photocatalytic conversion of CO_(2)into solar fuels provides a bright route for the green and sustainable development of human society.However,the realization of efficient photocatalytic CO_(2)reduction reaction(CO_(2)RR)is still challenging owing to the sluggish kinetics or unfavorable thermodynamics for basic chemical processes of CO_(2)RR,such as adsorption,activation,conversion and product desorption.To overcome these shortcomings,recent works have demonstrated that surface engineering of semiconductors,such as introducing surface vacancy,surface doping,and cocatalyst loading,serves as effective or promising strategies for improved photocatalytic CO_(2)RR with high activity and selectivity.The essential reason lies in the activation and reaction pathways can be optimized and regulated through the reconstruction of surface atomic and electronic structures.Herein,in this review,we focus on recent research advances about rational design of semiconductor surface for photocatalytic CO_(2)RR.The surface engineering strategies for improved CO_(2)adsorption,activation,and product selectivity will be reviewed.In addition,theoretical calculations along with in situ characterization techniques will be in the spotlight to clarify the kinetics and thermodynamics of the reaction process.The aim of this review is to provide deep understanding and rational guidance on the design of semiconductors for photocatalytic CO_(2)RR.
基金This work was supported by the National Natural Science Foundation of China(91745203)the State Key Laboratory of Pulp and Paper Engineering(2020C01)the Guangdong Pearl River Talent Program(2017GC010281).
文摘Solid oxide cells(SOCs)have attracted great attention in the past decades because of their high conversion efficiency,low environmental pollution and diversified fuel options.Nickel-based catalysts are the most widely used fuel electrode materials for SOCs due to the low price and high activity.However,when hydrocarbon fuels are employed,nickel-based electrodes face serious carbon deposition challenges,leading to a rapid decline of cell performance.Great efforts have been devoted to understanding the occurrence of the coking reaction,and to improving the stability of the electrodes in hydrocarbon fuels.In this review,we summarize recent research progress of utilizing surface modification to improve the stability and activity of Ni-based electrodes for SOCs by preventing carbon coking.The review starts with a briefly introduction about the reaction mechanism of carbon deposition,followed by listing several surface modification technologies and their working principles.Then we introduce representative works using surface modification strategies to prevent carbon coking on Ni-based electrodes.Finally,we highlight future direction of improving electrode catalytic activity and anti-coking performance through surface engineering.
基金National"973"Projects (G1999065009) andNational Natural Science Foundation of China (50075086)
文摘As system of a serial of technologies and engineering activities, remanufacturing aims at restoring and rebuilding waste machinery through advanced technologies and industrialized measures under the direction of the product total life cycle theory. With the development of surface engineering, nano-surface engineering has been one subject of intensive studies. In addition, nano-surface engineering has become an important means for property reforming and promoting of remanufacturing parts. Many low-dimension and nano-size or nano-structure functional coatings, which can improve materials properties evidently, are deposited by new methods. In this paper, some researches about the new achievement and remanufacturing application of the nano-stmctured coatings by different nano-surface engineering technologies in our laboratory were introduced. Especially, nano-structured DLC multilayer coatings by d.c. plasma CVD, nano-composed Al2O3/Ni, SiC/Ni and Diamond/Ni coatings by brush plating, and nano-composed Al2O3/TiO2 coating by plasma spraying were introduced in detail.
基金National Key R&D Program of China,Grant/Award Number:2021YFB2600900National Science Fund for Distinguished Young Scholars of China,Grant/Award Number:51925903+3 种基金National Natural Science Foundation of China,Grant/Award Numbers:52108195,U21A20150Natural Science Foundation of Jiangsu Province,Grant/Award Number:BK20210264Natural Sciences and Engineering Research Council of CanadaCanada Research Chairs Program。
文摘Peculiar hierarchical microstructures in creatures inspire modern material design with distinct functionalities.Creatures can effortlessly construct sophisticated yet long-range ordered microstructure across bio-membrane through ion secretion and precipitation.However,microstructure biomimicry in current technology generally requires elaborate,point-by-point fabrication.Herein,a spontaneous yet controllable strategy is developed to achieve surface microstructure engineering through a natural surface phenomenon similar to ion secretion-precipitation,that is,coupled dissolution-precipitation.A series of hierarchical microstructures on mineral surfaces in fluids with tunable morphology,orientation,dimension,and spatial distribution are achieved by simply controlling initial dissolution and fluid chemistry.In seawater,long-range ordered film of vertically aligned brucite flakes forms through interfacial dissolution,nucleation,and confinement-induced orientation of flakes with vertically grown{110}plane,on the edge of which,fusiform aragonite epitaxially precipitates.With negligible initial surface dissolution,prismatic aragonite epitaxially grows on a calcite polyhedron-packed surface.By tuning fluid chemistry,closely packed calcite polyhedron and loosely packed calcite micro-pillars are engineered through rapid and retarded precipitation,respectively.Surprisingly,the spontaneously grown microstructures resemble those deliberately created by human or found in nature,and tremendously modulate surface functionality.These findings open new possibilities for facile and customizable engineering of microstructural surfaces,hierarchical heterostructures,and biomimetic materials.
基金financially supported by the Scientific Research Fund of Hunan Provincial Education Department(No.21B0289)Changsha Municipal Science and Technology Projects(No.2022cskj006)。
文摘Surface engineering,which modulates the electronic structure and adsorption/desorption properties of electrocatalysts,is one of the key strategies for improving the catalytic performance.Herein,we demonstrate a facile solid-phase reaction for surface engineering of MnO_(2)to boost the oxygen reduction kinetics.Via reaction with surface hydroxy groups,La single atoms with loading amount up to 2.7 wt%are anchored onto a-MnO_(2)nanorods.After surface engineering,the oxygen reduction reaction(ORR)kinetics is significantly improved with the half-wave potential from 0.70 to 0.84 V,the number of transferred electrons from 2.5 to 3.9 and the limiting current density from 4.8 to 6.0 mA·cm^(-2).In addition,the catalyst delivers superior discharge performance in both alkaline and neutral metal–air batteries.Density functional theory(DFT)calculations reveal that atomic La modulates the surface electronic configuration of MnO_(2),reduces its d-band center and thus lowers the OOH*and O*reaction energy barrier.This work provides a new route for rational design of highly active electrocatalyst and holds great potential for application in various catalytic reactions.
文摘Electrolytic water splitting by renewable energy is a technology with great potential for producing hydrogen(H_(2))without carbon emission,but this technical route is hindered by its huge energy(electricity)cost,which is mainly wasted by the anode oxygen evolution reaction(OER)while the value of the anode product(oxygen)is very limited.Replacing the high-energy-cost OER with a selective organic compound electrooxidation carried out at a relatively lower potential can reduce the electricity cost while producing value-added chemicals.Currently,H_(2) generation coupled with synthesis of value-added organic compounds faces the challenge of low selectivity and slow generation rate of the anodic products.One-dimensional(1D)nanocatalysts with a unique morphology,well-defined active sites,and good electron conductivity have shown excellent performance in many electrocatalytic reactions.The rational design and regulation of 1D nanocatalysts through surface engineering can optimize the adsorption energy of intermediate molecules and improve the selectivity of organic electrooxidation reactions.Herein,we summarized the recent research progress of 1D nanocatalysts applied in different organic electrooxidation reactions and introduced several different fabrication strategies for surface engineering of 1D nanocatalysts.Then,we focused on the relationship between surface engineering and the selectivity of organic electrooxidation reaction products.Finally,future challenges and development prospects of 1D nanocatalysts in the coupled system consisting of organic electrooxidation and hydrogen evolution reactions are briefly outlined.
基金the financial support by the Ministry of Education of Singapore via the Tier-1 project A-8000192-01-00.
文摘Removal of boric acid from seawater and wastewater using reverse osmosis membrane technologies is imperative and yet remains inadequately addressed by current commercial membranes.Existing research efforts performed post-modification of reverse osmosis membranes to enhance boron rejection,which is usually accompanied by substantial sacrifice in water permeability.This study delves into the surface engineering of low-pressure reverse osmosis membranes,aiming to elevate boron removal efficiency while maintaining optimal salt rejection and water permeability.Membranes were modified by the self-polymerization and co-deposition of dopamine and polystyrene sulfonate at varying ratios and concentrations.The surfaces became smoother and more hydrophilic after modification.The optimum membrane exhibited a water permeability of 9.2±0.1 L·m^(-2)·h^(-1)·bar^(-1),NaCl rejection of 95.8%±0.3%,and boron rejection of 49.7%±0.1% and 99.6%±0.3% at neutral and alkaline pH,respectively.The water permeability is reduced by less than 15%,while the boron rejection is 3.7 times higher compared to the blank membrane.This research provides a promising avenue for enhancing boron removal in reverse osmosis membranes and addressing water quality concerns in the desalination process.
基金National Natural Science Foundation of China (22179008, 21875022)Yibin ‘Jie Bang Gua Shuai’ (2022JB004)+3 种基金support from the Beijing Nova Program (20230484241)support from the Postdoctoral Fellowship Program of CPSF (GZB20230931)Special Support of the Chongqing Postdoctoral Research Project (2023CQBSHTB2041)Initial Energy Science & Technology Co., Ltd (IEST)。
文摘Lithium-rich manganese-based oxides(LRMOs) exhibit high theoretical energy densities, making them a prominent class of cathode materials for lithium-ion batteries. However, the performance of these layered cathodes often declines because of capacity fading during cycling. This decline is primarily attributed to anisotropic lattice strain and oxygen release from cathode surfaces. Given notable structural transformations, complex redox reactions, and detrimental interface side reactions in LRMOs, the development of a single modification approach that addresses bulk and surface issues is challenging. Therefore,this study introduces a surface double-coupling engineering strategy that mitigates bulk strain and reduces surface side reactions. The internal spinel-like phase coating layer, featuring threedimensional(3D) lithium-ion diffusion channels, effectively blocks oxygen release from the cathode surface and mitigates lattice strain. In addition, the external Li_(3)PO_(4) coating layer, noted for its superior corrosion resistance, enhances the interfacial lithium transport and inhibits the dissolution of surface transition metals. Notably, the spinel phase, as excellent interlayer, securely anchors Li_(3)PO_(4) to the bulk lattice and suppresses oxygen release from lattices. Consequently, these modifications considerably boost structural stability and durability, achieving an impressive capacity retention of 83.4% and a minimal voltage decay of 1.49 m V per cycle after 150 cycles at 1 C. These findings provide crucial mechanistic insights into the role of surface modifications and guide the development of high-capacity cathodes with enhanced cyclability.
基金funded by the National Key Research and Development Program of China(2018YFA0900702).
文摘Biocatalysis in organic solvents(OSs)has numerous important applications,but native enzymes in OSs often exhibit limited catalytic performance.Herein,we proposed a computation-aided surface charge engineering strategy to improve the catalytic performance of haloalkane dehalogenase DhaA in OSs based on the energetic analysis of substrate binding to the DhaA surface.Several variants with enhanced OS resistance were obtained by replacing negative charged residues on the surface with positive charged residue(Arg).Particularly,a four-substitution variant E16R/E93R/E121R/E257R exhibited the best catalytic performance(five-fold improvement in OS resistance and seven-fold half-life increase in 40%(vol)dimethylsulfoxide).As a result,the overall catalytic performance of the variant could be at least 26 times higher than the wild-type DhaA.Fluorescence spectroscopy and molecular dynamics simulation studies revealed that the residue substitution mainly enhanced OS resistance from four aspects:(a)improved the overall structural stability,(b)increased the hydrophobicity of the local microenvironment around the catalytic triad,(c)enriched the hydrophobic substrate around the enzyme molecule,and(d)lowered the contact frequency between OS molecules and the catalytic triad.Our findings validate that computationaided surface charge engineering is an effective and ingenious rational strategy for tailoring enzyme performance in OSs.
基金This work was supported by the National Natural Science Foundation of China(21975074,91834301)the Innovation Program of Shanghai Municipal Education Commission,and the Fundamental Research Funds for the Central Universities.
文摘Layered oxide cathodes with high Ni content promise high energy density and competitive cost for Li-ion batteries(LIBs).However,Ni-rich cathodes suffer from irreversible interface reconstruction and undesirable cracking with severe performance degradation upon long-term operation,especially at elevated temperatures.Herein,we demonstrate in situ surface engineering of Ni-rich cathodes to construct a dual ion/electron-conductive NiTiO 3 coating layer and Ti gradient doping(NC90–Ti@NTO)in parallel.The dual-modification synergy helps to build a thin,robust cathode–electrolyte interface with rapid Li-ion transport and enhanced reaction kinetics,and effec-tively prevents unfavorable crystalline phase transformation during long-term cycling under harsh environments.The optimized NC90–Ti@NTO delivers a high reversible capacity of 221.0 mAh g^(-1) at 0.1C and 158.9 mAh g^(-1) at 10C.Impressively,it exhibits a capacity retention of 88.4%at 25?C after 500 cycles and 90.7%at 55?C after 300 cycles in a pouch-type full battery.This finding provides viable clues for stabilizing the lattice and interfacial chemistry of Ni-rich cathodes to achieve durable LIBs with high energy density.
基金This research was funded by Key Scientific Research Projects of General Universities in Guangdong Province,China(No.2021KCXTD086)Guangzhou Basic and Applied Basic Research Project in China(No.202102020134)Youth Innovation Talents Project of Guangdong Universities(natural science)in China(No.2019KQNCX098).
文摘Opportunities coexist with challenges for the development of carbon-based cathodes with a high energy density applied for zinc ion hybrid capacitors(ZIHCs).In the present study,a facile and effective surface engineering approach is demonstrated to greatly improve the energy storage ability of commercial carbon paper(CP)in ZIHC.Benefiting from the introduced oxygen functional groups,larger surface area and improved surface wettability upon air calcination,the assembled aqueous ZIHC with the functionalized carbon paper(FCP)exhibits a much higher areal capacity of 0.22 mAh/cm^(2)at 1 mA/cm^(2),outperforming the counterpart with blank CP by over 5000 times.More importantly,a superior energy density and power density of 130.8μWh/cm^(2)and 7460.5μW/cm^(2),are respectively delivered.Furthermore,more than 90%of the initial capacity is retained over 10000 cycles.This surface engineering strategy to improve the energy storage capability is potentially applicable to developing a wide range of high-energy carbon electrode materials.
基金financially supported by the National Natural Science Foundation of China (Nos.22062017 and 22164015)the Inner Mongolia Autonomous Region Program for Key Science and Technology (No.2020GG0161)+4 种基金the Natural Science Foundation of Inner Mongolia Autonomous Region (No.2019JQ03)the Ordos City Program for Key Science and Technology (No.2022YY003)the Open Project of State Key Laboratory of Supramolecular Structure and Materials (No.sklssm2022021)the Program of Higher-Level Talents of Inner Mongolia University (No.10000-22311201/035)the Science and Technology Research Projects in Colleges and Universities of Inner Mongolia Autonomous Region (No.NJZZ23091)。
文摘Nanosilver has been regarded as a promising alternative to traditional antibiotics for fighting pathogenassociated infections due to its efficacy toward a broad spectrum of pathogens.However,bacterial resistance to nanosilver has emerged recently.In this contribution,a surface engineering strategy based on N-halamine chemistry to address bacterial resistance to nanosilver was proposed.Using 1,3-dichloro-5,5-dimethylhydantoin(DCDMH)as an N-halamine source,AgCI nanodots were deposited on the surface of Ag nano wires(Ag NWs)via in situ redox reaction to prepare AgCl-on-Ag NWs.After in vitro and in vivo tests,AgCl-on-Ag NWs effectively inactivated two antibiotic-resistant bacteria,ampicillinresistant Escherichia coli(AREC)and methicillin-resistant Staphylococcus aureus(MRSA)with the minimum bactericidal concentration(MBC)as low as 10μg·ml~(-1)and exhibited good biosafety against normal cells.The experimental and theoretical tests demonstrated that AgCl-onAg NWs worked on AREC and MAS A by generating high level of reactive oxygen species under visible light irradiation,coupled with the sustained Ag ion release.Meanwhile,the antibacterial mechanism of AgCl-on-Ag NWs against MRSA was verified at the gene level by transcriptome analysis(RNA sequencing).Moreover,the fullthickness defect model verified that AgCl-on-Ag NWs reduced inflammatory cell infiltration and dramatically accelerated wound healing.This work provides a synergistic mechanism based on nanosilver surface engineering to eradicate the resistant bacteria that can alleviate drug resistance and develop an innovative approach for the treatment of bacterial infections.
文摘Late in-stent thrombus and restenosis still represent two major challenges in stents’design.Surface treatment of stent is attracting attention due to the increasing importance of stenting intervention for coronary artery diseases.Several surface engineering techniques have been utilised to improve the biological response in vivo on a wide range of biomedical devices.As a tailorable,precise,and ultra-fast process,laser surface engineering offers the potential to treat stent materials and fabricate various 3D textures,including grooves,pillars,nanowires,porous and freeform structures,while also modifying surface chemistry through nitridation,oxidation and coatings.Laser-based processes can reduce the biodegradable materials’degradation rate,offering many advantages to improve stents’performance,such as increased endothelialisation rate,prohibition of SMC proliferation,reduced platelet adhesion and controlled corrosion and degradation.Nowadays,adequate research has been conducted on laser surface texturing and surface chemistry modification.Laser texturing on commercial stents has been also investigated and a promotion of performance of laser-textured stents has been proved.In this critical review,the influence of surface texture and surface chemistry on stents performance is firstly reviewed to understand the surface characteristics of stents required to facilitate cellular response.This is followed by the explicit illustration of laser surface engineering of stents and/or related materials.Laser induced periodic surface structure(LIPSS)on stent materials is then explored,and finally the application of laser surface modification techniques on latest generation of stent devices is highlighted to provide future trends and research direction on laser surface engineering of stents.
基金National Natural Science Foundation of China(Nos.82073807 and 81973277)the WorldClass Universities(Disciplines)and the Characteristic Development Guidance Funds for the Central Universities(No.PY3A012,China)for financial support。
文摘Biomimetic nanoengineering presents great potential in biomedical research by integrating cell membrane(CM) with functional nanoparticles. However, preparation of CM biomimetic nanomaterials for custom applications that can avoid the aggregation of nanocarriers while maintaining the biological activity of CM remains a challenge. Herein, a high-performance CM biomimetic graphene nanodecoy was fabricated via purposeful surface engineering, where polyethylene glycol(PEG) was used to modifying magnetic graphene oxide(MGO) to improve its stability in physiological solution, so as to improve the screening efficiency to active components of traditional Chinese medicine(TCM). With this strategy, the constructed PEGylated MGO(PMGO) could keep stable at least 10 days, thus improving the CM coating efficiency. Meanwhile, by taking advantage of the inherent ability of He La cell membrane(HM) to interact with specific ligands, HM-camouflaged PMGO showed satisfied adsorption capacity(116.2 mg/g) and selectivity. Finally, three potential active components, byakangelicol, imperatorin,and isoimperatorin, were screened from Angelica dahurica, whose potential antiproliferative activity were further validated by pharmacological studies. These results demonstrated that the purposeful surfaceengineering is a promising strategy for the design of efficient CM biomimetic nanomaterials, which will promote the development of active components screening in TCM.
基金This work was financially supported by the Ministry of Science and Technology of China （Grant No. 2010CB832904）, NSAF （Grant No. U1230111）, and the National Natural Science Foundation of China （NSFC Grant Nos. 91226202, 11175024 and 11375031）.
文摘In the past decade, nanopores have been developed extensively for various potential applications, and their performance greatly depends on the surface properties of the nanopores. Atomic layer deposition （ALD） is a new technology for depositing thin films, which has been rapidly developed from a niche technology to an established method. ALD films can cover the surface in confined regions even in nanoscale conformally, thus it is proved to be a powerful tool to modify the surface of the synthetic nanopores and also to fabricate complex nanopores. This review gives a brief introduction on nanopore synthesis and ALD fundamental knowledge, and then focuses on the various aspects of synthetic nanopores processing by ALD and their applications, including single-molecule sensing, nanofiuidic devices, nanostructure fabrication and other applications.
