Objective:To evaluate the effect of the clinical nursing pathway applied to functional exercise in patients with hip replacements before and after the operation.Methods:The China National Knowledge Infrastructure(CNKI...Objective:To evaluate the effect of the clinical nursing pathway applied to functional exercise in patients with hip replacements before and after the operation.Methods:The China National Knowledge Infrastructure(CNKI),WanFang Data,Chinese science and technology journal database(VIP),PubMed,Web of Science,EMBASE,CBM and the Cochrane Library(2015-5) were searched for randomized controlled trials(RCTs) on clinical nursing pathways for functional exercise in patients with hip replacements before and after surgery from June 2015 to January2010.The references included in the literature were also retrieved.To meet the literature standard,2reviewers independently selected and extracted data according to the inclusion criteria and assessed the risks of bias.RevMan 5.3 software was used in this meta-analysis.The quality of evidence was evaluated using grade profiler3.6 software,the level recommended for grading.Results:A total of 15 RCTs and 1248 patients were included.The meta-analysis showed that,in the clinical nursing path group,the Harris score of hip function[SMD = 3.35,95%CI(2.53.4.16),P < 0.00001]and incidence of thrombosis embolism[RR = 0.28,95%CI(0.15,0.53),P < 0.0001],pulmonary infection[RR = 0.33,95%CI(0.14,0.82),P = 0.02],urinary retention[RR = 0.22,95%CI(0.09.0.52),P = 0.0005],constipation[RR = 0.20,95%CI(0.10,0.40),P < 0.00001],patients' satisfaction for nursing care[RR = 1.26,95%CI(1.17,1.36),P< 0.000011 and shortened hospitalization times[SMD =-1.91,95%CI(-2.39.-1.43),P < 0.0001[were statistically significantly better than those in the control group.However,in reducing joint dislocations[RR- 0.25,95%CI(0.05,1.15),P = 0.08],pressure ulcers[RR = 0.25,95%CI(0.03,2.19),P=0.21],and incidence of complications[RR = 0.42,95%CI(0.15.1.12),P = 0.08],there was no statistically significant difference between the two groups.Funnel plot analysis of the average length of stay showed that there might be some publication bias in the literature.The GRADE evaluation results showed that the level of Harris scores for hip function was moderate and the incidence of thrombosis,urinary retention and satisfaction of patients regarding nursing were low,and the rest of the factors analyzed were very low.Conclusions:The effect of the clinical nursing pathway applied to functional exercises in patients with hip replacements before and after surgery was significantly better than that of routine nursing.However,it was restricted by the evaluation grade of the research results and the standardization and uniformity of the research.The results of the above study need to be verified by more high-quality RCTs.展开更多
To systematically evaluate the clinical efficacy and safety of Maren Runchang Pill(麻仁润肠丸)in the treatment of senile constipation.Randomized controlled trials(RCT)on the treatment of senile constipation with Maren...To systematically evaluate the clinical efficacy and safety of Maren Runchang Pill(麻仁润肠丸)in the treatment of senile constipation.Randomized controlled trials(RCT)on the treatment of senile constipation with Maren Runchang Pill(麻仁润肠丸)were searched by computer in CNKI,CBM,WanFang,VIP,PubMed,EMbase and the Cochrane Library databases.The retrieval time limit was from the establishment of the database to May 2019.A total of 2 researchers independently screened literature and extracted data according to the inclusion criteria,and Meta-analyzed the RCT that met the standards by applying RevMan5.3 software.A total of 5 randomized controlled trials were included,including 395 patients with senile constipation,199 in the experimental group and 196 in the control group.The treatment group was treated with Maren Runchang Pill(麻仁润肠丸),while the control group was treated with other Western medicine,including fruit guide tablets,lactulose oral liquid or kaisailu,etc.The results of Meta-analysis showed that there was no significant difference in the total clinical efficacy between Maren Runchang Pill(麻仁润肠丸)and other Western medicines[RR=1.02,95%CI(0.88,1.17),P=0.83].In terms of improvement of abdominal distension and inappetence,there was no significant difference between the treatment with Maren Runchang Pill(麻仁润肠丸)and other Western medicine[RR=1.03,95%CI(0.85,1.24),P=0.78].Maren Runchang Pill(麻仁润肠丸).This study showed that the efficacy of Maren Runchang Pill(麻仁润肠丸)in the treatment of senile constipation was not significantly different from that of conventional Western medicine,and was safe,and effective,with few adverse reactions.Maren Runchang Pill(麻仁润肠丸),as a traditional Chinese patent medicine,can play the role of regulating qi and replenishing blood,and regulating bowel and bowel laxative,with fewer cost.It is more suitable for the elderly to use,with good compliance,and clinically it should be used with syndrome differentiation.However,due to the quantity and quality of the original study,multi-center,high-quality randomized controlled trials are still needed to further confirm it.展开更多
Objective: To re-evaluate the systematic review of Rheumatoid arthritis (RA) treatmentwith total glucosides of paeony (TGP) to provide evidence-based evidence for the treatmentof RA with TGP in the clinic. Methods: A ...Objective: To re-evaluate the systematic review of Rheumatoid arthritis (RA) treatmentwith total glucosides of paeony (TGP) to provide evidence-based evidence for the treatmentof RA with TGP in the clinic. Methods: A total of eight databases including CNKI, Wan FangData, CBM, VIP, PubMed, Embase, Cochrane Library, and Web of Science were searched bycomputer for the systematic reviews/meta-analyses concerning the treatment of RA withTGP. The retrieval period was from the establishment of the database to May 2, 2022.Literature screening was conducted based on the randomized controlled trial, and thematerials of the included literature were extracted. Using the preferred reporting items forsystematic reviews and meta-analyses statement. The a measurement tool to assesssystematic reviews 2 scale and grades of recommendation, assessment, development, andevaluation system evaluated the reporting quality, methodological quality, and outcomeindicators evidence levels included in the literature. Results: Six systematicreviews/meta-analysis literature were finally included. Evaluation of the preferred reportingitems for systematic reviews and meta-analyses statement showed that the overall reportingquality of included literature was low, and only one piece with high quality was included.The results of the a measurement tool to assess systematic reviews 2 scale evaluationshowed that the qualities of included literature were all low-level and highly low-level. Thegrades of recommendation, assessment, development, and evaluation evidence qualityevaluation showed a total of 39 outcome indicators in the six included literature, and alloutcome indicators were intermediate, low-level, and extremely low in evidence evaluation.Conclusion: Many pieces of evidence show that TGP has certain advantages in alleviatingclinical symptoms, reducing adverse reactions, and reducing hepatotoxicity in the treatmentof RA, but this conclusion lacks high-level evidence to support it, which needs to be provedby more studies in the future.展开更多
With the advent of the pandemic, the Brazilian Ministry of Health structured in record time the Telehealth Service of the Unified Health System called TeleSUS, an ecosystem based on the intensive use of information te...With the advent of the pandemic, the Brazilian Ministry of Health structured in record time the Telehealth Service of the Unified Health System called TeleSUS, an ecosystem based on the intensive use of information technology involving automated mechanisms and a personalized health care center at distance. In addition to constant evaluations carried out in the service as a public health strategy, at clinical and epidemiological levels, the team involved in the project was also concerned with evaluating the system developed to enable the operation of remote care, from the conception of the organization of health actions to the technological development of the digital health tool. The objective of this study was to carry out an evaluation of a telehealth system, measuring the degree of satisfaction of users of health professionals regarding its usability and identifying factors that positively and/or negatively influence the evaluation.展开更多
Agricultural irrigation is a primary user for freshwater withdrawal. Irrigation plays an important role in crop production, as it provides the benefit of reducing the effects of prolonged dryness and erratic precipita...Agricultural irrigation is a primary user for freshwater withdrawal. Irrigation plays an important role in crop production, as it provides the benefit of reducing the effects of prolonged dryness and erratic precipitation. Center pivot irrigation system is the most common irrigation system in agriculture. As the center pivot irrigation system ages, the system could develop a leaking joint, clogged sprinklers, and physical damage. This can cause areas of non-uniformity that can lead to under- or over-irrigated in some areas of the land, resulting in excess energy use and cost, wasting resources, and environmental impacts. Thus, it is important to evaluate the performance of a center pivot irrigation system regularly to maximize return on investments and minimize wasting resources. This study focuses on evaluating the impacts and benefits of improved center pivot irrigation distribution uniformity by performing distribution uniformity evaluations pre- and post-retrofit. This study also focused on demonstrating an unmanned aerial vehicle (UAV) to assess the performance of the center pivot irrigation system in two irrigated farmlands. The Coefficient of Uniformity (CU), Distribution Uniformity (DU), and Scheduling Coefficient (SC) were calculated based on the catch can test data. The values were utilized to evaluate water and energy savings from the improved coefficients. The team has found that replacing sprinkler packages increased the CU from 78 to 89 and the DU from 77 to 82, and reduced the SC from 1.3 to 1.2 in Field A. In Field B, replacing sprinkler packages increased the CU from 73 to 91 and the DU from 62 to 84 and reduced the SC from 1.6 to 1.2. The estimated water savings in Field A due to the reduced scheduling coefficient was approximately 151,000 liters/hectare/year, with consideration of the corn and soybean rotation field in Michigan. The estimated water savings in Field B was 608,000 liters/hectare/year. The data from this demonstration study showed the value of distribution uniformity evaluation and retrofit of irrigation systems. This information will encourage farmers and agricultural industries to consider performing more distribution uniformity evaluations, ultimately improving irrigation water use efficiency and supporting sustainable water management in agriculture.展开更多
To evaluate the effectiveness and safety of Jinye Baidu Granules(金叶败毒颗粒)for acute upper respiratory tract infection(AURTI).Database such as CNKI,Wan-fang,VIP,Sino Med,Web of science,Clinical Trials gov,Medline、...To evaluate the effectiveness and safety of Jinye Baidu Granules(金叶败毒颗粒)for acute upper respiratory tract infection(AURTI).Database such as CNKI,Wan-fang,VIP,Sino Med,Web of science,Clinical Trials gov,Medline、EMBASE,CENTRAL,Cochrane Library were retrieved to collect randomized controlled trials(RCTs)on Jinye Baidu Granules(金叶败毒颗粒)in treating AURTI from the estabslishment of the database to March 2019.A total of 2 reviewers independently screened the literature according to the inclusion and exclusion criteria,and extracted material and the quality evaluation of the included studies.Quality evaluation adopted Cochrane Handbook 5.1 evaluation standards and tools.Rev Man5.3 was used to perform Meta-analysis for the adopted study.Finally a total of 4 RCTs involving 636 patients were included.Meta-analysis results showed that:compared with conventional Western medicine alone,Jinye Baidu Granules(金叶败毒颗粒)combined with Western medicine in the treatment of acute upper respiratory tract infection can improve the total effective rate of clinical efficacy[RR=0.13,95%CI(0.06,0.29),P<0.00001],shorten the time of antipyretic time for acute upper respiratory tract infection[MD=–1.22,95%CI(–1.43,–1.00),P<0.00001],shorten the time of pharyngeal pain[MD=–1.97,95%CI(–2.97,–0.96),P<0.0001]and shorten the cough disappear time[MD=–1.97,95%CI(–2.97,–0.96),P<0.0001].There were 2 papers reporting adverse reactions during the study period,and one of them specifically reported diarrhea,nausea,vomiting and stomachache in the experimental group.In the control group:diarrhea,nausea and adverse reactions disappeared after drug withdrawal;the incidence of adverse reactions was 3.92%in the control group and 5.88%in the observation group.There was no significant difference between the 2 groups(P>0.05).Based on existing data and methods,the systematic evaluation showed that,compared with Western medicine alone,Jinye Baidu Granules(金叶败毒颗粒)combined with Western medicine alone could improve the total effective rate of clinical efficacy,reduce the time of fever,sore throat,and the disappearance of cough with less adverse reactions.However,due to the low quality of the included study,large samples,multicenter,randomized,double-blind trials and trials are still needed to randomized controlled trials with reference to the CONSORT standard and the STRICTA statement.展开更多
Financial regulation and supervision is an important subject in finance research. After the U. S. subprime mortgage crisis,the weakness in this field becomes the research focus. Every country attaches importance to st...Financial regulation and supervision is an important subject in finance research. After the U. S. subprime mortgage crisis,the weakness in this field becomes the research focus. Every country attaches importance to strengthen the financial supervision and management. But the financial regulatory system is a large system,and the process of model building and index selection is very complicated. A model for China's financial regulation and supervision system was proposed and a system evaluation method was improved. A more exact result was drawn by choosing 2003- 2009 index data.展开更多
Objective:Through literature research,the distribution of TCM constitution of nonalcoholic fatty liver(NAFLD)was discussed,the common constitution types of the disease were determined,and medical evidence was provided...Objective:Through literature research,the distribution of TCM constitution of nonalcoholic fatty liver(NAFLD)was discussed,the common constitution types of the disease were determined,and medical evidence was provided for the prevention and treatment of NAFLD by traditional Chinese medicine.Methods:The literatures on the correlation between NAFLD and TCM constitution published in domestic journals from the database establishment to April 2020 were searched with"non-alcoholic fatty liver disease and TCM constitution"as the search term,and screening,quality evaluation and data extraction were conducted according to the na exclusion criteria.Statistical software stata16.0 was used for meta analysis of the included literature.Results:Sixteen studies were included.The results showed that the proportions of TCM constitution types and 95%CI of NAFLD patients were phlegm-dampness0.28(0.24,0.31),moisture-heat0.16(0.13,0.20),qi-asthenia0.13(0.10,0.16),qi-stagnation0.11(0.06,0.17),qi-stagnation0.08(0.06,0.10),yi-stagnation0.08(0.06,0.10),yi--stagnation0.08(0.06,0.10),blood stasis0.07(0.04,0.08),yang-asthenia0.06(0.04,0.08),and special report 0.02(0.01,0.02).Conclusion:The common constitution types of patients with nonalcoholic fatty liver are phlegm-dam-pness,damp-heat,q-asthenia,and mild,especially phlegm-dampness,which are most closely related to nonalcoholic fatty liver.展开更多
Objective:To systematically evaluate the effects of statins combined with trimetazidine on the regulation of inflammatory factors and the improvement of ventricular remodeling in coronary atherosclerotic heart disease...Objective:To systematically evaluate the effects of statins combined with trimetazidine on the regulation of inflammatory factors and the improvement of ventricular remodeling in coronary atherosclerotic heart disease based on the inflammasomes/immune damage response theory.Methods:Using computer to search for EMbase,The Cochrane Library,Web of Science,MEDLINE,PubMed,WanFang Data,CNKI,China Biomedical Document Service System(CBM),VIP database(VIP),9 databases in total.The search time limit is from the inception of the databases to June 7,2021.All reference documents included in the study were manually searched.According to the Cochrane systematic review method,the information on atorvastatin combined with trimetazidine and conventional treatment(antiplatelet,control blood pressure,diuresis,coronary artery dilation and other expectant treatments)contrast the use of trimetazidine or stains combined with expectant treatment of coronary atherosclerotic heart disease patients in Chinese and English randomized controlled trials(RCT),and conduct the extraction and quality evaluation of the included literature data,using RevMan5.4 software for Meta analysis.Outcome indicators include inflammatory factors:C-reactive protein(CRP),IL-6(interleukin 6),tumor necrosis factor(TNF-α),and ventricular remodeling related outcome indicators:left ventricular end diastolic diameter(LVEDD),left Ventricular end systolic diameter(LVESD).Results:12 randomized controlled trials were included,a total of 1120 patients with coronary heart disease.Meta-analysis results:(1)inflammatory factors:the statin combined with trimetazidine group can significantly reduce the CRP,IL-6,TNF-α’s expression degree in the blood of patients with coronary heart disease compared with the control group(only statins or trimetazidine).CRP[n=770,SMD=-2.70,95%CI(-2.55,-1.40),P<-0.00001],TNF-α[n=678,SMD=-2.25,95%CI(-3.39,-1.12),P<-0.0001],IL-6[n=770,SMD=-2.10,95%CI(-3.10,-1.10),P<0.00001].(2)Ventricular remodeling:Compared with the control group(using statins or trimetazidine alone),the statin combined with trimetazidine group can significantly reduce the left ventricular end-systolic diameter of patients with coronary heart disease before treatment[n=626,SMD=-1.55,95%CI(-2.10,-0.99),P<-0.00001]and leftVentricular end diastolic diameter[n=626,SMD=-1.18,95%CI(-1.56,-0.80),P<-0.00001].Conclusion:Compared with the control group,statins combined with trimetazidine can significantly reduce the level of inflammatory factors based on the inflammasomes/immune injury response theory,and improve the ventricular remodeling in patients with coronary heart disease.展开更多
Objective:Through literature research,the distribution of TCM constitution of nonalcoholic fatty liver(NAFLD)was discussed,the common constitution types of the disease were determined,and medical evidence was provided...Objective:Through literature research,the distribution of TCM constitution of nonalcoholic fatty liver(NAFLD)was discussed,the common constitution types of the disease were determined,and medical evidence was provided for the prevention and treatment of NAFLD by traditional Chinese medicine.Methods:The literatures on the correlation between NAFLD and TCM constitution published in domestic journals from the database establishment to April 2020 were searched with"non-alcoholic fatty liver disease and TCM constitution"as the search term,and screening,quality evaluation and data extraction were conducted according to the na exclusion criteria.Statistical software stata16.0 was used for meta analysis of the included literature.Results:Sixteen studies were included.The results showed that the proportions of TCM constitution types and 95%CI of NAFLD patients were phlegm-dampness0.28(0.24,0.31),moisture-heat0.16(0.13,0.20),qi-asthenia0.13(0.10,0.16),qi-stagnation0.11(0.06,0.17),qi-stagnation0.08(0.06,0.10),yi-stagnation0.08(0.06,0.10),yi--stagnation0.08(0.06,0.10),blood stasis0.07(0.04,0.08),yang-asthenia0.06(0.04,0.08),and special report 0.02(0.01,0.02).Conclusion:The common constitution types of patients with nonalcoholic fatty liver are phlegm-dam-pness,damp-heat,q-asthenia and mild,especially phlegm-dampness,which are most closely related to nonalcoholic fatty liver.展开更多
Objective:To A randomized controlled trial(RCTS)of lung tonifying and kidney tonifying in the treatment of chronic obstructive pulmonary disease(copd)by meta-analysis.Methods:Computer retrieval of databases such as C...Objective:To A randomized controlled trial(RCTS)of lung tonifying and kidney tonifying in the treatment of chronic obstructive pulmonary disease(copd)by meta-analysis.Methods:Computer retrieval of databases such as CNKI、VIP、WanFang、Cochrane Library、EMbase、PubMed.The retrieval time was from the database construction to March 2020,and two evaluators were selected to screen the documents according to the na sorting standards,extract the data with Excel 2010 software,and perform Meta analysis with Rev Man5.3 software.Results:21 RCTS were included.Meta-analysis results show that compared with the conventional treatment,the method of supplementing lung and tonifying kidney can obviously improve lung function(MD=1.69,95%CI[1.36,2.01],P<0.00001)、reduce TCM syndrome score(MD=39.83,95%CI[18.10,61.56],P=0.0003)、improve life quality(MD=-5.90,95%CI[-8.95,-2.85],P=0.0001)、regulates serum immunoglobulin(MD=0.37,95%CI[0.31,0.44],P<0.00001)、improve 6MWD(MD=39.83,95%CI[18.10,61.56],P=0.0003)、improve CAT(MD=-1.68,95%CI[-2.05,-1.30],P<0.00001).The differences were statistically significant.For improved T lymphocyte subsets(MD=0.96,95%CI[-0.10,2.03],P=0.08)not statistically significant.Conclusion:Lung-tonifying kidney-tonifying method had better efficacy in improving lung function,reducing TCM syndrome score,improving quality of life,improving immunoglobulin,improving 6WMD,improving CAT,but the efficacy in improving t-lymphocyte subgroup was similar to that in the control group.Due to the limited quantity and quality of samples included in this paper,more multicenter randomized controlled trials with rigorous design of large samples should be carried out for verification.展开更多
Single Pilot Operations(SPO),as a NextGen concept of operation,can save both crew costs and human resources for airlines,and has attracted the attention of aviation researchers.To explore in advance the problems that ...Single Pilot Operations(SPO),as a NextGen concept of operation,can save both crew costs and human resources for airlines,and has attracted the attention of aviation researchers.To explore in advance the problems that the introduction of SPO into the aviation system would bring,the Human-Centered Design(HCD)approach has been widely used in the development of SPO.A systematic review of the progress of HCD approach in SPO research can promote further development of SPO.In this paper,the literature resources of SPO were firstly retrieved from scientific research databases by subject search and were used as the input of scientometric analysis to obtain the highly cited literature,the number of annual publications,and the co-authorship network,which enables readers to understand the research trends and research groups of current SPO.Secondly,the development,application,and research process of the HCD approach were introduced in detail,and the progress of the HCD approach in SPO research was reviewed systematically from three aspects:concept design,function allocation,and system evaluation.Finally,limitations of current SPO research and future research directions for applying the HCD approach to SPO were also discussed.展开更多
文摘Objective:To evaluate the effect of the clinical nursing pathway applied to functional exercise in patients with hip replacements before and after the operation.Methods:The China National Knowledge Infrastructure(CNKI),WanFang Data,Chinese science and technology journal database(VIP),PubMed,Web of Science,EMBASE,CBM and the Cochrane Library(2015-5) were searched for randomized controlled trials(RCTs) on clinical nursing pathways for functional exercise in patients with hip replacements before and after surgery from June 2015 to January2010.The references included in the literature were also retrieved.To meet the literature standard,2reviewers independently selected and extracted data according to the inclusion criteria and assessed the risks of bias.RevMan 5.3 software was used in this meta-analysis.The quality of evidence was evaluated using grade profiler3.6 software,the level recommended for grading.Results:A total of 15 RCTs and 1248 patients were included.The meta-analysis showed that,in the clinical nursing path group,the Harris score of hip function[SMD = 3.35,95%CI(2.53.4.16),P < 0.00001]and incidence of thrombosis embolism[RR = 0.28,95%CI(0.15,0.53),P < 0.0001],pulmonary infection[RR = 0.33,95%CI(0.14,0.82),P = 0.02],urinary retention[RR = 0.22,95%CI(0.09.0.52),P = 0.0005],constipation[RR = 0.20,95%CI(0.10,0.40),P < 0.00001],patients' satisfaction for nursing care[RR = 1.26,95%CI(1.17,1.36),P< 0.000011 and shortened hospitalization times[SMD =-1.91,95%CI(-2.39.-1.43),P < 0.0001[were statistically significantly better than those in the control group.However,in reducing joint dislocations[RR- 0.25,95%CI(0.05,1.15),P = 0.08],pressure ulcers[RR = 0.25,95%CI(0.03,2.19),P=0.21],and incidence of complications[RR = 0.42,95%CI(0.15.1.12),P = 0.08],there was no statistically significant difference between the two groups.Funnel plot analysis of the average length of stay showed that there might be some publication bias in the literature.The GRADE evaluation results showed that the level of Harris scores for hip function was moderate and the incidence of thrombosis,urinary retention and satisfaction of patients regarding nursing were low,and the rest of the factors analyzed were very low.Conclusions:The effect of the clinical nursing pathway applied to functional exercises in patients with hip replacements before and after surgery was significantly better than that of routine nursing.However,it was restricted by the evaluation grade of the research results and the standardization and uniformity of the research.The results of the above study need to be verified by more high-quality RCTs.
基金Supported by National Key Research&Development Plan(2018YFC1707400,2018YFC1707410)。
文摘To systematically evaluate the clinical efficacy and safety of Maren Runchang Pill(麻仁润肠丸)in the treatment of senile constipation.Randomized controlled trials(RCT)on the treatment of senile constipation with Maren Runchang Pill(麻仁润肠丸)were searched by computer in CNKI,CBM,WanFang,VIP,PubMed,EMbase and the Cochrane Library databases.The retrieval time limit was from the establishment of the database to May 2019.A total of 2 researchers independently screened literature and extracted data according to the inclusion criteria,and Meta-analyzed the RCT that met the standards by applying RevMan5.3 software.A total of 5 randomized controlled trials were included,including 395 patients with senile constipation,199 in the experimental group and 196 in the control group.The treatment group was treated with Maren Runchang Pill(麻仁润肠丸),while the control group was treated with other Western medicine,including fruit guide tablets,lactulose oral liquid or kaisailu,etc.The results of Meta-analysis showed that there was no significant difference in the total clinical efficacy between Maren Runchang Pill(麻仁润肠丸)and other Western medicines[RR=1.02,95%CI(0.88,1.17),P=0.83].In terms of improvement of abdominal distension and inappetence,there was no significant difference between the treatment with Maren Runchang Pill(麻仁润肠丸)and other Western medicine[RR=1.03,95%CI(0.85,1.24),P=0.78].Maren Runchang Pill(麻仁润肠丸).This study showed that the efficacy of Maren Runchang Pill(麻仁润肠丸)in the treatment of senile constipation was not significantly different from that of conventional Western medicine,and was safe,and effective,with few adverse reactions.Maren Runchang Pill(麻仁润肠丸),as a traditional Chinese patent medicine,can play the role of regulating qi and replenishing blood,and regulating bowel and bowel laxative,with fewer cost.It is more suitable for the elderly to use,with good compliance,and clinically it should be used with syndrome differentiation.However,due to the quantity and quality of the original study,multi-center,high-quality randomized controlled trials are still needed to further confirm it.
基金National Natural Science Foundation of China(NO.81804050)Henan province traditional Chinese medicine scientific research special major subject(NO.20-21ZYZD05)Henan province traditional Chinese medicine scientific research special general subject(NO.2022ZY1062).
文摘Objective: To re-evaluate the systematic review of Rheumatoid arthritis (RA) treatmentwith total glucosides of paeony (TGP) to provide evidence-based evidence for the treatmentof RA with TGP in the clinic. Methods: A total of eight databases including CNKI, Wan FangData, CBM, VIP, PubMed, Embase, Cochrane Library, and Web of Science were searched bycomputer for the systematic reviews/meta-analyses concerning the treatment of RA withTGP. The retrieval period was from the establishment of the database to May 2, 2022.Literature screening was conducted based on the randomized controlled trial, and thematerials of the included literature were extracted. Using the preferred reporting items forsystematic reviews and meta-analyses statement. The a measurement tool to assesssystematic reviews 2 scale and grades of recommendation, assessment, development, andevaluation system evaluated the reporting quality, methodological quality, and outcomeindicators evidence levels included in the literature. Results: Six systematicreviews/meta-analysis literature were finally included. Evaluation of the preferred reportingitems for systematic reviews and meta-analyses statement showed that the overall reportingquality of included literature was low, and only one piece with high quality was included.The results of the a measurement tool to assess systematic reviews 2 scale evaluationshowed that the qualities of included literature were all low-level and highly low-level. Thegrades of recommendation, assessment, development, and evaluation evidence qualityevaluation showed a total of 39 outcome indicators in the six included literature, and alloutcome indicators were intermediate, low-level, and extremely low in evidence evaluation.Conclusion: Many pieces of evidence show that TGP has certain advantages in alleviatingclinical symptoms, reducing adverse reactions, and reducing hepatotoxicity in the treatmentof RA, but this conclusion lacks high-level evidence to support it, which needs to be provedby more studies in the future.
文摘With the advent of the pandemic, the Brazilian Ministry of Health structured in record time the Telehealth Service of the Unified Health System called TeleSUS, an ecosystem based on the intensive use of information technology involving automated mechanisms and a personalized health care center at distance. In addition to constant evaluations carried out in the service as a public health strategy, at clinical and epidemiological levels, the team involved in the project was also concerned with evaluating the system developed to enable the operation of remote care, from the conception of the organization of health actions to the technological development of the digital health tool. The objective of this study was to carry out an evaluation of a telehealth system, measuring the degree of satisfaction of users of health professionals regarding its usability and identifying factors that positively and/or negatively influence the evaluation.
文摘Agricultural irrigation is a primary user for freshwater withdrawal. Irrigation plays an important role in crop production, as it provides the benefit of reducing the effects of prolonged dryness and erratic precipitation. Center pivot irrigation system is the most common irrigation system in agriculture. As the center pivot irrigation system ages, the system could develop a leaking joint, clogged sprinklers, and physical damage. This can cause areas of non-uniformity that can lead to under- or over-irrigated in some areas of the land, resulting in excess energy use and cost, wasting resources, and environmental impacts. Thus, it is important to evaluate the performance of a center pivot irrigation system regularly to maximize return on investments and minimize wasting resources. This study focuses on evaluating the impacts and benefits of improved center pivot irrigation distribution uniformity by performing distribution uniformity evaluations pre- and post-retrofit. This study also focused on demonstrating an unmanned aerial vehicle (UAV) to assess the performance of the center pivot irrigation system in two irrigated farmlands. The Coefficient of Uniformity (CU), Distribution Uniformity (DU), and Scheduling Coefficient (SC) were calculated based on the catch can test data. The values were utilized to evaluate water and energy savings from the improved coefficients. The team has found that replacing sprinkler packages increased the CU from 78 to 89 and the DU from 77 to 82, and reduced the SC from 1.3 to 1.2 in Field A. In Field B, replacing sprinkler packages increased the CU from 73 to 91 and the DU from 62 to 84 and reduced the SC from 1.6 to 1.2. The estimated water savings in Field A due to the reduced scheduling coefficient was approximately 151,000 liters/hectare/year, with consideration of the corn and soybean rotation field in Michigan. The estimated water savings in Field B was 608,000 liters/hectare/year. The data from this demonstration study showed the value of distribution uniformity evaluation and retrofit of irrigation systems. This information will encourage farmers and agricultural industries to consider performing more distribution uniformity evaluations, ultimately improving irrigation water use efficiency and supporting sustainable water management in agriculture.
文摘To evaluate the effectiveness and safety of Jinye Baidu Granules(金叶败毒颗粒)for acute upper respiratory tract infection(AURTI).Database such as CNKI,Wan-fang,VIP,Sino Med,Web of science,Clinical Trials gov,Medline、EMBASE,CENTRAL,Cochrane Library were retrieved to collect randomized controlled trials(RCTs)on Jinye Baidu Granules(金叶败毒颗粒)in treating AURTI from the estabslishment of the database to March 2019.A total of 2 reviewers independently screened the literature according to the inclusion and exclusion criteria,and extracted material and the quality evaluation of the included studies.Quality evaluation adopted Cochrane Handbook 5.1 evaluation standards and tools.Rev Man5.3 was used to perform Meta-analysis for the adopted study.Finally a total of 4 RCTs involving 636 patients were included.Meta-analysis results showed that:compared with conventional Western medicine alone,Jinye Baidu Granules(金叶败毒颗粒)combined with Western medicine in the treatment of acute upper respiratory tract infection can improve the total effective rate of clinical efficacy[RR=0.13,95%CI(0.06,0.29),P<0.00001],shorten the time of antipyretic time for acute upper respiratory tract infection[MD=–1.22,95%CI(–1.43,–1.00),P<0.00001],shorten the time of pharyngeal pain[MD=–1.97,95%CI(–2.97,–0.96),P<0.0001]and shorten the cough disappear time[MD=–1.97,95%CI(–2.97,–0.96),P<0.0001].There were 2 papers reporting adverse reactions during the study period,and one of them specifically reported diarrhea,nausea,vomiting and stomachache in the experimental group.In the control group:diarrhea,nausea and adverse reactions disappeared after drug withdrawal;the incidence of adverse reactions was 3.92%in the control group and 5.88%in the observation group.There was no significant difference between the 2 groups(P>0.05).Based on existing data and methods,the systematic evaluation showed that,compared with Western medicine alone,Jinye Baidu Granules(金叶败毒颗粒)combined with Western medicine alone could improve the total effective rate of clinical efficacy,reduce the time of fever,sore throat,and the disappearance of cough with less adverse reactions.However,due to the low quality of the included study,large samples,multicenter,randomized,double-blind trials and trials are still needed to randomized controlled trials with reference to the CONSORT standard and the STRICTA statement.
文摘Financial regulation and supervision is an important subject in finance research. After the U. S. subprime mortgage crisis,the weakness in this field becomes the research focus. Every country attaches importance to strengthen the financial supervision and management. But the financial regulatory system is a large system,and the process of model building and index selection is very complicated. A model for China's financial regulation and supervision system was proposed and a system evaluation method was improved. A more exact result was drawn by choosing 2003- 2009 index data.
基金Shaanxi administration of traditional Chinese medicine-Changan medical school of Zhang's liver disease inheritance studio(2018).
文摘Objective:Through literature research,the distribution of TCM constitution of nonalcoholic fatty liver(NAFLD)was discussed,the common constitution types of the disease were determined,and medical evidence was provided for the prevention and treatment of NAFLD by traditional Chinese medicine.Methods:The literatures on the correlation between NAFLD and TCM constitution published in domestic journals from the database establishment to April 2020 were searched with"non-alcoholic fatty liver disease and TCM constitution"as the search term,and screening,quality evaluation and data extraction were conducted according to the na exclusion criteria.Statistical software stata16.0 was used for meta analysis of the included literature.Results:Sixteen studies were included.The results showed that the proportions of TCM constitution types and 95%CI of NAFLD patients were phlegm-dampness0.28(0.24,0.31),moisture-heat0.16(0.13,0.20),qi-asthenia0.13(0.10,0.16),qi-stagnation0.11(0.06,0.17),qi-stagnation0.08(0.06,0.10),yi-stagnation0.08(0.06,0.10),yi--stagnation0.08(0.06,0.10),blood stasis0.07(0.04,0.08),yang-asthenia0.06(0.04,0.08),and special report 0.02(0.01,0.02).Conclusion:The common constitution types of patients with nonalcoholic fatty liver are phlegm-dam-pness,damp-heat,q-asthenia,and mild,especially phlegm-dampness,which are most closely related to nonalcoholic fatty liver.
基金General Project of the National Natural Science Foundation of China(81973686)National Key Research and Development Program Project(2019YFC0840608)。
文摘Objective:To systematically evaluate the effects of statins combined with trimetazidine on the regulation of inflammatory factors and the improvement of ventricular remodeling in coronary atherosclerotic heart disease based on the inflammasomes/immune damage response theory.Methods:Using computer to search for EMbase,The Cochrane Library,Web of Science,MEDLINE,PubMed,WanFang Data,CNKI,China Biomedical Document Service System(CBM),VIP database(VIP),9 databases in total.The search time limit is from the inception of the databases to June 7,2021.All reference documents included in the study were manually searched.According to the Cochrane systematic review method,the information on atorvastatin combined with trimetazidine and conventional treatment(antiplatelet,control blood pressure,diuresis,coronary artery dilation and other expectant treatments)contrast the use of trimetazidine or stains combined with expectant treatment of coronary atherosclerotic heart disease patients in Chinese and English randomized controlled trials(RCT),and conduct the extraction and quality evaluation of the included literature data,using RevMan5.4 software for Meta analysis.Outcome indicators include inflammatory factors:C-reactive protein(CRP),IL-6(interleukin 6),tumor necrosis factor(TNF-α),and ventricular remodeling related outcome indicators:left ventricular end diastolic diameter(LVEDD),left Ventricular end systolic diameter(LVESD).Results:12 randomized controlled trials were included,a total of 1120 patients with coronary heart disease.Meta-analysis results:(1)inflammatory factors:the statin combined with trimetazidine group can significantly reduce the CRP,IL-6,TNF-α’s expression degree in the blood of patients with coronary heart disease compared with the control group(only statins or trimetazidine).CRP[n=770,SMD=-2.70,95%CI(-2.55,-1.40),P<-0.00001],TNF-α[n=678,SMD=-2.25,95%CI(-3.39,-1.12),P<-0.0001],IL-6[n=770,SMD=-2.10,95%CI(-3.10,-1.10),P<0.00001].(2)Ventricular remodeling:Compared with the control group(using statins or trimetazidine alone),the statin combined with trimetazidine group can significantly reduce the left ventricular end-systolic diameter of patients with coronary heart disease before treatment[n=626,SMD=-1.55,95%CI(-2.10,-0.99),P<-0.00001]and leftVentricular end diastolic diameter[n=626,SMD=-1.18,95%CI(-1.56,-0.80),P<-0.00001].Conclusion:Compared with the control group,statins combined with trimetazidine can significantly reduce the level of inflammatory factors based on the inflammasomes/immune injury response theory,and improve the ventricular remodeling in patients with coronary heart disease.
基金Shaanxi administration of TCM-Changan medical school of Zhang's liver disease inheritance studio(2018)
文摘Objective:Through literature research,the distribution of TCM constitution of nonalcoholic fatty liver(NAFLD)was discussed,the common constitution types of the disease were determined,and medical evidence was provided for the prevention and treatment of NAFLD by traditional Chinese medicine.Methods:The literatures on the correlation between NAFLD and TCM constitution published in domestic journals from the database establishment to April 2020 were searched with"non-alcoholic fatty liver disease and TCM constitution"as the search term,and screening,quality evaluation and data extraction were conducted according to the na exclusion criteria.Statistical software stata16.0 was used for meta analysis of the included literature.Results:Sixteen studies were included.The results showed that the proportions of TCM constitution types and 95%CI of NAFLD patients were phlegm-dampness0.28(0.24,0.31),moisture-heat0.16(0.13,0.20),qi-asthenia0.13(0.10,0.16),qi-stagnation0.11(0.06,0.17),qi-stagnation0.08(0.06,0.10),yi-stagnation0.08(0.06,0.10),yi--stagnation0.08(0.06,0.10),blood stasis0.07(0.04,0.08),yang-asthenia0.06(0.04,0.08),and special report 0.02(0.01,0.02).Conclusion:The common constitution types of patients with nonalcoholic fatty liver are phlegm-dam-pness,damp-heat,q-asthenia and mild,especially phlegm-dampness,which are most closely related to nonalcoholic fatty liver.
基金National Natural Science Foundation of China(No.81473564)。
文摘Objective:To A randomized controlled trial(RCTS)of lung tonifying and kidney tonifying in the treatment of chronic obstructive pulmonary disease(copd)by meta-analysis.Methods:Computer retrieval of databases such as CNKI、VIP、WanFang、Cochrane Library、EMbase、PubMed.The retrieval time was from the database construction to March 2020,and two evaluators were selected to screen the documents according to the na sorting standards,extract the data with Excel 2010 software,and perform Meta analysis with Rev Man5.3 software.Results:21 RCTS were included.Meta-analysis results show that compared with the conventional treatment,the method of supplementing lung and tonifying kidney can obviously improve lung function(MD=1.69,95%CI[1.36,2.01],P<0.00001)、reduce TCM syndrome score(MD=39.83,95%CI[18.10,61.56],P=0.0003)、improve life quality(MD=-5.90,95%CI[-8.95,-2.85],P=0.0001)、regulates serum immunoglobulin(MD=0.37,95%CI[0.31,0.44],P<0.00001)、improve 6MWD(MD=39.83,95%CI[18.10,61.56],P=0.0003)、improve CAT(MD=-1.68,95%CI[-2.05,-1.30],P<0.00001).The differences were statistically significant.For improved T lymphocyte subsets(MD=0.96,95%CI[-0.10,2.03],P=0.08)not statistically significant.Conclusion:Lung-tonifying kidney-tonifying method had better efficacy in improving lung function,reducing TCM syndrome score,improving quality of life,improving immunoglobulin,improving 6WMD,improving CAT,but the efficacy in improving t-lymphocyte subgroup was similar to that in the control group.Due to the limited quantity and quality of samples included in this paper,more multicenter randomized controlled trials with rigorous design of large samples should be carried out for verification.
基金This research was funded by the Natural Science Foundation of Shanghai,China(No.20ZR1427800)the New Young Teachers Launch Program of Shanghai Jiao Tong University,China(No.20X100040036).
文摘Single Pilot Operations(SPO),as a NextGen concept of operation,can save both crew costs and human resources for airlines,and has attracted the attention of aviation researchers.To explore in advance the problems that the introduction of SPO into the aviation system would bring,the Human-Centered Design(HCD)approach has been widely used in the development of SPO.A systematic review of the progress of HCD approach in SPO research can promote further development of SPO.In this paper,the literature resources of SPO were firstly retrieved from scientific research databases by subject search and were used as the input of scientometric analysis to obtain the highly cited literature,the number of annual publications,and the co-authorship network,which enables readers to understand the research trends and research groups of current SPO.Secondly,the development,application,and research process of the HCD approach were introduced in detail,and the progress of the HCD approach in SPO research was reviewed systematically from three aspects:concept design,function allocation,and system evaluation.Finally,limitations of current SPO research and future research directions for applying the HCD approach to SPO were also discussed.
