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Exploring the regulatory mechanism of tRNA-derived fragments 36 in acute pancreatitis based on small RNA sequencing and experiments 被引量:2
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作者 Xi-Rui Fan Yun Huang +4 位作者 Yu Su Si-Jin Chen Yu-Lu Zhang Wei-Kang Huang Hui Wang 《World Journal of Gastroenterology》 SCIE CAS 2023年第30期4642-4656,共15页
BACKGROUND Acute pancreatitis(AP)is a disease featuring acute inflammation of the pancreas and histological destruction of acinar cells.Approximately 20%of AP patients progress to moderately severe or severe pancreati... BACKGROUND Acute pancreatitis(AP)is a disease featuring acute inflammation of the pancreas and histological destruction of acinar cells.Approximately 20%of AP patients progress to moderately severe or severe pancreatitis,with a case fatality rate of up to 30%.However,a single indicator that can serve as the gold standard for prognostic prediction has not been discovered.Therefore,gaining deeper insights into the underlying mechanism of AP progression and the evolution of the disease and exploring effective biomarkers are important for early diagnosis,progression evaluation,and precise treatment of AP.AIM To determine the regulatory mechanisms of tRNA-derived fragments(tRFs)in AP based on small RNA sequencing and experiments.METHODS Small RNA sequencing and functional enrichment analyses were performed to identify key tRFs and the potential mechanisms in AP.Reverse transcription quantitative polymerase chain reaction(RT-qPCR)was conducted to determine tRF expression.AP cell and mouse models were created to investigate the role of tRF36 in AP progression.Lipase,amylase,and cytokine levels were assayed to examine AP progression.Ferritin expression,reactive oxygen species,malondialdehyde,and ferric ion levels were assayed to evaluate cellular ferroptosis.RNA pull down assays and methylated RNA immunoprecipitation were performed to explore the molecular mechanisms.RESULTS RT-qPCR results showed that tRF36 was significantly upregulated in the serum of AP patients,compared to healthy controls.Functional enrichment analysis indicated that target genes of tRF36 were involved in ferroptosisrelated pathways,including the Hippo signaling pathway and ion transport.Moreover,the occurrence of pancreatic cell ferroptosis was detected in AP cells and mouse models.The results of interference experiments and AP cell models suggested that tRF-36 could promote AP progression through the regulation of ferroptosis.Furthermore,ferroptosis gene microarray,database prediction,and immunoprecipitation suggested that tRF-36 accelerated the progression of AP by recruiting insulin-like growth factor 2 mRNA binding protein 3(IGF2BP3)to the p53 mRNA m6A modification site by binding to IGF2BP3,which enhanced p53 mRNA stability and promoted the ferroptosis of pancreatic follicle cells.CONCLUSION In conclusion,regulation of nuclear pre-mRNA domain-containing protein 1B promoted AP development by regulating the ferroptosis of pancreatic cells,thereby acting as a prospective therapeutic target for AP.In addition,this study provided a basis for understanding the regulatory mechanisms of tRFs in AP. 展开更多
关键词 Acute pancreatitis trna-derived fragments trna-derived fragments 36 Mouse models Ferroptosis Reverse transcription quantitative polymerase chain reaction
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Identification of tRNA-derived Fragments and Their Potential Roles in Atherosclerosis 被引量:2
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作者 Jian WANG Pei-kang DONG +10 位作者 Xiu-feng XU Tao HUANG Shuai MAO Qing-guo WANG Jie HAO Xiao-hong LIU Xiao-dong SUN Kai KANG Quan ZHANG Jing-tian LI Tao WANG 《Current Medical Science》 2021年第4期712-721,共10页
Objective Atherosclerosis(AS),a chronic inflammatory disease,is the basis of cardiovascular disease(CVD).Although the treatment has been greatly improved,AS still imposes a large burden on human health and the medical... Objective Atherosclerosis(AS),a chronic inflammatory disease,is the basis of cardiovascular disease(CVD).Although the treatment has been greatly improved,AS still imposes a large burden on human health and the medical system,and we still need to further study its pathogenesis.As a novel biomolecule,transfer RNA-derived fragments(tRFs)play a key role in the progression of various disease.However,whether tRFs contribute to atherosclerosis pathogenesis remains unexplored.Methods With deep sequencing technology,the change of tRFs expression profiles in patients with AS compared to healthy control group was identified.The accuracy of the sequencing data was validated using RT qPCR.Subsequently,we predicted the potential target genes of tRFs by online miRNA target prediction algorithms.The potential functions of tRFs were evaluated with Gene Ontology(GO)and Kyoto Encyclopedia of Genes and Genomes(KEGG)pathway analyses.Results There were 13 tRFs differentially expressed between patients with AS and healthy controls,of which 2 were up-regulated and 11 were down-regulated.Validation by RT-qPCR analysis confirmed the sequencing results,and tRF-Gly-GCC-009 was highly up-regulated in the AS group based on the results of sequencing which was confirmed by RT-qPCR analysis.Furthermore,GO enrichment and KEGG pathway analyses indicated that 10 signaling pathways were related to tRF-Gly-GCC-009.These pathways might be physiopathological fundamentals of AS,mainly involving in Apelin signaling,Notch signaling and calcium signaling.Conclusion The results of our study provide important novel insight into the underlying pathogenesis and demonstrate that tRFs might be potential biomarkers and therapeutic targets for AS in the future. 展开更多
关键词 ATHEROSCLEROSIS noncoding RNAs transfer RNA-derived fragments bioinformatic prediction
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tRNA^(Glu)-derived fragments from embryonic extracellular vesicles modulate bovine embryo hatching
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作者 Yuan Fan Krishna Chaitanya Pavani +2 位作者 Katrien Smits Ann Van Soom Luc Peelman 《Journal of Animal Science and Biotechnology》 SCIE CAS CSCD 2024年第4期1559-1566,共8页
Transfer RNA-derived small RNAs(tsRNAs)have been shown to be involved in early embryo development and repression of endogenous retroelements in embryos and stem cells.However,it is unknown whether tsRNAs also regulate... Transfer RNA-derived small RNAs(tsRNAs)have been shown to be involved in early embryo development and repression of endogenous retroelements in embryos and stem cells.However,it is unknown whether tsRNAs also regulate embryo hatching.In this study,we mined the sequencing data of a previous experiment in which we demonstrated that the microRNA(miRNA)cargo of preimplantation embryonic extracellular vesicles(EVs)influences embryo development.We thus profiled the tsRNA cargo of EVs secreted by blastocysts and non-blastocysts.The majority of tsRNAs was identified as tRNA halves originating from the 5'ends of tRNAs.Among the 148 differentially expressed tsRNAs,the 19 nt tRNA fragment(tRF)tDR-14:32-Glu-CTC-1 was found to be significantly up-regulated in EVs derived from non-blastocysts.RT-qPCR assays confirmed its significant up-regulation in non-blastocyst embryos and their conditioned medium compared to the blastocyst group(P<0.05).Inhibition of tDR-14:32-Glu-CTC-1 by supplementing antagomirs to the conditioned medium improved embryo hatching(P<0.05).Transcriptomic analysis of embryos treated with tDR-14:32-Glu-CTC-1 antagomirs further showed differential expression of genes that are associated with embryo hatching and implantation.In summary,tDR-14:32-Glu-CTC-1 is up-regulated in non-blastocyst embryos and their secretions,and inhibition of tDR-14:32-Glu-CTC-1 promotes embryo hatching,while influencing embryo implantation-related genes and pathways.These results indicate that embryonic EVs containing specific tRFs may regulate preimplantation embryo development. 展开更多
关键词 EMBRYO Extracellular vesicles HATCHING tRNA fragments ts RNAs
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Warhead fragments motion trajectories tracking and spatio-temporal distribution reconstruction method based on high-speed stereo photography
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作者 Pengyu Hu Jiangpeng Wu +3 位作者 Zhengang Yan Meng He Chao Liang Hao Bai 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2024年第7期162-172,共11页
High speed photography technique is potentially the most effective way to measure the motion parameter of warhead fragment benefiting from its advantages of high accuracy,high resolution and high efficiency.However,it... High speed photography technique is potentially the most effective way to measure the motion parameter of warhead fragment benefiting from its advantages of high accuracy,high resolution and high efficiency.However,it faces challenge in dense objects tracking and 3D trajectories reconstruction due to the characteristics of small size and dense distribution of fragment swarm.To address these challenges,this work presents a warhead fragments motion trajectories tracking and spatio-temporal distribution reconstruction method based on high-speed stereo photography.Firstly,background difference algorithm is utilized to extract the center and area of each fragment in the image sequence.Subsequently,a multi-object tracking(MOT)algorithm using Kalman filtering and Hungarian optimal assignment is developed to realize real-time and robust trajectories tracking of fragment swarm.To reconstruct 3D motion trajectories,a global stereo trajectories matching strategy is presented,which takes advantages of epipolar constraint and continuity constraint to correctly retrieve stereo correspondence followed by 3D trajectories refinement using polynomial fitting.Finally,the simulation and experimental results demonstrate that the proposed method can accurately track the motion trajectories and reconstruct the spatio-temporal distribution of 1.0×10^(3)fragments in a field of view(FOV)of 3.2 m×2.5 m,and the accuracy of the velocity estimation can achieve 98.6%. 展开更多
关键词 Warhead fragment measurement High speed photography Stereo vision Multi-object tracking Spatio-temporal reconstruction
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A cloud model target damage effectiveness assessment algorithm based on spatio-temporal sequence finite multilayer fragments dispersion
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作者 Hanshan Li Xiaoqian Zhang Junchai Gao 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2024年第10期48-64,共17页
To solve the problem of target damage assessment when fragments attack target under uncertain projectile and target intersection in an air defense intercept,this paper proposes a method for calculating target damage p... To solve the problem of target damage assessment when fragments attack target under uncertain projectile and target intersection in an air defense intercept,this paper proposes a method for calculating target damage probability leveraging spatio-temporal finite multilayer fragments distribution and the target damage assessment algorithm based on cloud model theory.Drawing on the spatial dispersion characteristics of fragments of projectile proximity explosion,we divide into a finite number of fragments distribution planes based on the time series in space,set up a fragment layer dispersion model grounded in the time series and intersection criterion for determining the effective penetration of each layer of fragments into the target.Building on the precondition that the multilayer fragments of the time series effectively assail the target,we also establish the damage criterion of the perforation and penetration damage and deduce the damage probability calculation model.Taking the damage probability of the fragment layer in the spatio-temporal sequence to the target as the input state variable,we introduce cloud model theory to research the target damage assessment method.Combining the equivalent simulation experiment,the scientific and rational nature of the proposed method were validated through quantitative calculations and comparative analysis. 展开更多
关键词 Target damage Cloud model fragments dispersion Effectiveness assessment Spatio-temporal sequence
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Double casing warhead with sandwiched charge:The axial distribution of fragments velocities
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作者 Ping Ye Yongxiang Dong +5 位作者 Qitian Sun Peizhuo Shi Wang Yao Yongnan Li Yujing Li Mingze Li 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2024年第4期201-216,共16页
The double casing warhead with sandwiched charge is a novel fragmentation warhead that can produce two groups of fragments with different velocity,and the previous work has presented a calculation formula to determine... The double casing warhead with sandwiched charge is a novel fragmentation warhead that can produce two groups of fragments with different velocity,and the previous work has presented a calculation formula to determine the maximum fragment velocity.The current work builds on the published formula to further develop a formula for calculating the axial distribution characteristics of the fragment velocity.For this type of warhead,the simulation of the dispersion characteristics of the detonation products at different positions shows that the detonation products at the ends have a much larger axial velocity than those in the middle,and the detonation products have a greater axial dispersion velocity when they are closer to the central axis.The loading process and the fragment velocity vary with the axial position for both casing layers,and the total velocity of the fragments is the vector sum of the radial velocity and the axial velocity.At the same axial position,the acceleration time of the inner casing is greater than that of the outer casing.For the same casing,the fragments generated at the ends have a longer acceleration time than the fragments from the middle.The proposed formula is validated with the X-ray radiography results of the four warheads previously tested experimentally and the 3D smoothedparticle hydrodynamics numerical simulation results of several series of new warheads with different configurations.The formula can accurately and reliably calculate the fragment velocity when the lengthto-diameter ratio of the charge is greater than 1.5 and the thickness of the casing is less than 20%its inner radius.This work thus provides a key reference for the theoretical analysis and the design of warheads with multiple casings. 展开更多
关键词 Double casing warhead Sandwiched charge fragment velocity Rarefaction wave Gurney formula Explosive loading
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Relationships between distribution characteristics of ceramic fragments and anti-penetration performance of ceramic composite bulletproof insert plates 被引量:1
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作者 Wen-hao Yu Wei-ping Li +3 位作者 Yi-fan Shangguan Xin-yang Ji Tian Ma Guo-qing Wu 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2023年第1期103-110,共8页
Through quantitative statistics and morphological characterization of ceramic fragments for ceramic composite bulletproof insert plates(CCBIPs),distribution characteristics of ceramic fragments within a specific size ... Through quantitative statistics and morphological characterization of ceramic fragments for ceramic composite bulletproof insert plates(CCBIPs),distribution characteristics of ceramic fragments within a specific size range were analyzed for different Armor Piercing Incendiary(API)and shot times.To quantitatively evaluate the effect of energy absorption for ceramic plates,a model of energy absorption during penetration for CCBIPs was established based on statistics of the size distribution of ceramic fragments(SDCF).Variation in the SDCF and its influence on energy absorption for CCBIPs were investigated.The results indicate that the distribution feature of ceramic fragments in the range of 0.25-2.25 mm is Gaussian distribution.Compared with Type 56 of API(56-API),ceramic fragments formed by 53-API with higher kinetic energy possess more quantity and more concentrated distribution,whose average equivalence size decreases by 6.5%,corresponding to increasing by 83.9%of estimated energy absorption.Besides,the ability of CCBIPs to resist the third shot is significantly weakened,whose estimated energy absorption decreases by 58.8%compared with the first shot.More concentrated distribution and fewer fragments are formed after the third shot,the average equivalence size of ceramic fragments increases by 6.9%,which may attribute to the micro-cracks induced by the previous two shots. 展开更多
关键词 Bulletproof insert plate Ceramic fragment Statistic Energy absorption Anti-penetration performance
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Debris cloud structure and hazardous fragments distribution under hypervelocity yaw impact 被引量:1
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作者 Chenyang Wu Qi-Guang He +2 位作者 Xiaowei Chen Chunbo Zhang Zebin Shen 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2023年第9期169-183,共15页
This study investigates how the debris cloud structure and hazardous fragment distribution vary with attack angle by simulating a circular cylinder projectile hypervelocity impinging on a thin plate using the finite e... This study investigates how the debris cloud structure and hazardous fragment distribution vary with attack angle by simulating a circular cylinder projectile hypervelocity impinging on a thin plate using the finite element-smoothed particle hydrodynamics(FE-SPH)adaptive method.Based on the comparison and analysis of the experimental and simulation results,the FE-SPH adaptive method was applied to address the hypervelocity yaw impact problem,and the variation law of the debris cloud structure with the attack angle was obtained.The screening criterion of the hazardous fragment at yaw impact is given by analyzing the debris formation obtained by the FE-SPH adaptive method,and the distribution characteristics of hazardous fragments and their relationship with the attack angle are given.Moreover,the velocity space was used to evaluate the distribution range and damage capability of asymmetric hazardous fragments.The maximum velocity angle was extended from fully symmetrical working conditions to asymmetrical cases to describe the asymmetrical debris cloud distribution range.In this range,the energy density was calculated to quantitatively analyze how much damage hazardous fragments inflict on the rear plate.The results showed that the number of hazardous fragments generated by the case near the 35°attack angle was the largest,the distribution range was the smallest,and the energy density was the largest.These results suggest that in this case,debris cloud generated by the impact had the strongest damage to the rear plate. 展开更多
关键词 Debris cloud Hypervelocity yaw impact FE-SPH adaptive method Velocity space Hazardous fragments distribution
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Enhancing rock fragmentation prediction in mining operations:A hybrid GWO-RF model with SHAP interpretability 被引量:1
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作者 ZHANG Yu-lin QIU Yin-gui +2 位作者 ARMAGHANI Danial Jahed MONJEZI Masoud ZHOU Jian 《Journal of Central South University》 SCIE EI CAS CSCD 2024年第8期2916-2929,共14页
In the mining industry,precise forecasting of rock fragmentation is critical for optimising blasting processes.In this study,we address the challenge of enhancing rock fragmentation assessment by developing a novel hy... In the mining industry,precise forecasting of rock fragmentation is critical for optimising blasting processes.In this study,we address the challenge of enhancing rock fragmentation assessment by developing a novel hybrid predictive model named GWO-RF.This model combines the grey wolf optimization(GWO)algorithm with the random forest(RF)technique to predict the D_(80)value,a critical parameter in evaluating rock fragmentation quality.The study is conducted using a dataset from Sarcheshmeh Copper Mine,employing six different swarm sizes for the GWO-RF hybrid model construction.The GWO-RF model’s hyperparameters are systematically optimized within established bounds,and its performance is rigorously evaluated using multiple evaluation metrics.The results show that the GWO-RF hybrid model has higher predictive skills,exceeding traditional models in terms of accuracy.Furthermore,the interpretability of the GWO-RF model is enhanced through the utilization of SHapley Additive exPlanations(SHAP)values.The insights gained from this research contribute to optimizing blasting operations and rock fragmentation outcomes in the mining industry. 展开更多
关键词 BLASTING rock fragmentation random forest grey wolf optimization hybrid tree-based technique
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Numerical and experimental investigation on hydraulic-electric rock fragmentation of heterogeneous granite 被引量:1
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作者 Xiaohua Zhu Ling He +3 位作者 Weiji Liu Yunxu Luo Youjian Zhang Wuji Tang 《International Journal of Mining Science and Technology》 SCIE EI CAS CSCD 2024年第1期15-29,共15页
Hydraulic-electric rock fragmentation(HERF)plays a significant role in improving the efficiency of high voltage pulse rock breaking.However,the underlying mechanism of HERF remains unclear.In this study,considering th... Hydraulic-electric rock fragmentation(HERF)plays a significant role in improving the efficiency of high voltage pulse rock breaking.However,the underlying mechanism of HERF remains unclear.In this study,considering the heterogeneity of the rock,microscopic thermodynamic properties,and shockwave time domain waveforms,based on the shockwave model,digital imaging technology and the discrete element method,the cyclic loading numerical simulations of HERF is achieved by coupling electrical,thermal,and solid mechanics under different formation temperatures,confining pressure,initial peak voltage,electrode bit diameter,and loading times.Meanwhile,the HERF discharge system is conducive to the laboratory experiments with various electrical parameters and the resulting broken pits are numerically reconstructed to obtain the geometric parameters.The results show that,the completely broken area consists of powdery rock debris.In the pre-broken zone,the mineral cementation of the rock determines the transition of type CⅠcracks to type CⅡand type CⅢcracks.Furthermore,the peak pressure of the shockwave increased with initial peak voltage but decreased with electrode bit diameter,while the wave front time reduced.Moreover,increasing well depth,formation temperature and confining pressure augment and inhibit HERF,but once confining pressure surpassed the threshold of 60 MPa for 152.40,215.90,and 228.60 mm electrode bits,and 40 MPa for 309.88 mm electrode bits,HERF is promoted.Additionally,for the same kind of rock,the volume and width of the broken pit increase with higher initial peak voltage and rock fissures will promote HERF.Eventually,the electrode drill bit with a 215.90 mm diameter is more suitable for drilling pink granite.This research contributes to a better microscopic understanding of HERF and provides valuable insights for electrode bit selection,as well as the optimization of circuit parameters for HERF technology. 展开更多
关键词 Hydraulic-electric rock fragmentation SHOCKWAVE Thermodynamics MICROCRACKS Weak Linear Parallel Bond Model
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Lead spall velocity of fragments of ultra-high-performance concrete slabs under partially embedded cylindrical charge-induced explosion
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作者 Yi Fan Li Chen +2 位作者 Heng-bo Xiang Qin Fang Fang-yu Han 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2023年第5期50-59,共10页
When an explosion occurs close to or partially within the face of a concrete structure, fragments are rapidly launched from the opposite face of the structure owing to concrete spalling, posing a significant risk to n... When an explosion occurs close to or partially within the face of a concrete structure, fragments are rapidly launched from the opposite face of the structure owing to concrete spalling, posing a significant risk to nearby personnel and equipment. To study the lead fragment velocity of ultra-high-performance concrete(UHPC), partially embedded explosion experiments were performed on UHPC slabs of limited thickness using a cylindrical trinitrotoluene charge. The launch angles and velocities of the resulting fragments were the determined using images collected by high-speed camera to document the concrete spalling and fragment launching process. The results showed that UHPC slabs without fiber reinforcement had a fragment velocity distribution of 0-118.3 m/s, which are largely identical to that for a normal-strength concrete(NSC) slab. In addition, the fragment velocity was negatively correlated to the angle between the velocity vector and vertical direction. An empirical Eq. for the lead spall velocity of UHPC and NSC slabs was then proposed based on a large volume of existing experimental data. 展开更多
关键词 Ultra-high-performance concrete Reinforced concrete slabs Explosion fragment velocity Blast resistance
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SPAGINS:semiempirical parameterization for fragments in gamma-induced nuclear spallation
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作者 Hui‑Ling Wei Meng‑Die Zhou +8 位作者 Pu Jiao Yu‑Ting Wang Jie Pu Kai‑Xuan Cheng Ya‑Fei Guo Chun‑Yuan Qiao Gong‑Tao Fan Hong‑Wei Wang Chun‑Wang Ma 《Nuclear Science and Techniques》 SCIE EI CAS CSCD 2023年第12期112-122,共11页
From the empirical phenomena of fragment distributions in nuclear spallation reactions,semiempirical formulas named SPAGINS were constructed to predict fragment cross-sections in high-energyγ-induced nuclear spallati... From the empirical phenomena of fragment distributions in nuclear spallation reactions,semiempirical formulas named SPAGINS were constructed to predict fragment cross-sections in high-energyγ-induced nuclear spallation reactions(PNSR).In constructing the SPAGINS formulas,theoretical models,including the TALYS toolkit,SPACS,and Rudstam formulas,were employed to study the general phenomenon of fragment distributions in PNSR with incident energies ranging from 100 to 1000 MeV.Considering the primary characteristics of PNSR,the SPAGINS formulas modify the EPAX and SPACS formulas and efficiently reproduce the measured data.The SPAGINS formulas provide a new and effective tool for predicting fragment production in PNSR. 展开更多
关键词 High-energy gamma-rays Spallation reaction fragment cross-section Empirical formula EPAX SPACS TALYS
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Fracture behavior and mechanism of highly fragmented steel cylindrical shell under explosive loading
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作者 Kang Wang Peng Chen +5 位作者 Xingyun Sun Yufeng Liu Jiayu Meng Xiaoyuan Li Xiongwei Zheng Chuan Xiao 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2024年第6期122-132,共11页
An in-depth understanding of the fracture behavior and mechanism of metallic shells under internal explosive loading can help develop material designs for warheads and regulate the quantity and mass distribution of th... An in-depth understanding of the fracture behavior and mechanism of metallic shells under internal explosive loading can help develop material designs for warheads and regulate the quantity and mass distribution of the fragments formed.This study investigated the fragmentation performance of a new high-carbon silicon-manganese(HCSiMn)steel cylindrical shell through fragment recovery experiments.Compared with the conventional 45Cr steel shell,the number of small mass fragments produced by the HCSi Mn steel shell was significantly increased with a scale parameter of 0.57 g fitted by the Weibull distribution model.The fragmentation process of the HCSi Mn shell exhibited more brittle tensile fracture characteristics,with the microcrack damage zone on the outer surface being the direct cause of its high fragmentation.On the one hand,the doping of alloy elements resulted in grain refinement by forming metallographic structure of tempered sorbite,so that microscopic intergranular fracture reduces the characteristic mass of the fragments;on the other hand,the distribution of alloy carbides can exert a"pinning"effect on the substrate grains,causing more initial cracks to form and propagate along the brittle carbides,further improving the shell fragmentation.Although the killing power radius for light armored vehicles was slightly reduced by about 6%,the dense killing radius of HCSiMn steel projectile against personnel can be significantly increased by about 26%based on theoretical assessment.These results provided an experimental basis for high fragmentation warhead design,and to some extent,revealed the correlation mechanism between metallographic structure and shell fragmentation. 展开更多
关键词 Projectile fragmentation fragment mass distribution Fracture mode Metallographic structure Damage power
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Assessing forest cover changes and fragmentation in the Himalayan temperate region: implications for forest conservation and management
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作者 Kaleem Mehmood Shoaib Ahmad Anees +6 位作者 Akhtar Rehman Aqil Tariq Qijing Liu Sultan Muhammad Fazli Rabbi Shao’an Pan Wesam Atef Hatamleh 《Journal of Forestry Research》 SCIE EI CAS CSCD 2024年第4期128-141,共14页
This study comprehensively assessed long-term vegetation changes and forest fragmentation dynamics in the Himalayan temperate region of Pakistan from 1989 to 2019.Four satellite images,including Landsat-5 TM and Lands... This study comprehensively assessed long-term vegetation changes and forest fragmentation dynamics in the Himalayan temperate region of Pakistan from 1989 to 2019.Four satellite images,including Landsat-5 TM and Landsat-8 Operational Land Imager(OLI),were chosen for subsequent assessments in October 1989,2001,2011 and 2019.The classified maps of 1989,2001,2011 and 2019 were created using the maximum likelihood classifier.Post-classification comparison showed an overall accuracy of 82.5%and a Kappa coefficient of 0.79 for the 2019 map.Results revealed a drastic decrease in closed-canopy and open-canopy forests by 117.4 and 271.6 km^(2),respectively,and an increase in agriculture/farm cultivation by 1512.8 km^(2).The two-way ANOVA test showed statistically significant differences in the area of various cover classes.Forest fragmentation was evaluated using the Landscape Fragmentation Tool(LFT v2.0)between 1989 and 2019.The large forest core(>2.00 km^(2))decreased from 149.4 to 296.7 km^(2),and a similar pattern was observed in medium forest core(1.00-2.00 km^(2))forests.On the contrary,the small core(<1.00 km^(2))forest increased from 124.8 to 145.3 km^(2) in 2019.The perforation area increased by 296.9 km^(2),and the edge effect decreased from 458.9 to 431.7 km^(2).The frequency of patches also increased by 119.1 km^(2).The closed and open canopy classes showed a decreasing trend with an annual rate of 0.58%and 1.35%,respectively.The broad implications of these findings can be seen in the studied region as well as other global ecological areas.They serve as an imperative baseline for afforestation and reforestation operations,highlighting the urgent need for efficient management,conservation,and restoration efforts.Based on these findings,sustainable land-use policies may be put into place that support local livelihoods,protect ecosystem services,and conserve biodiversity. 展开更多
关键词 Natural catastrophes Landsat Change detection Forest fragmentation Landscape fragmentation tool(LFT) AFFORESTATION REFORESTATION
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Comparison of microwave- and thermal-assisted rock fragmentation methods at different temperatures and loading rates
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作者 Wei Yao Shuai Wang +2 位作者 Bangbiao Wu Ying Xu Kaiwen Xia 《International Journal of Mining Science and Technology》 SCIE EI CAS CSCD 2024年第6期799-819,共21页
Understanding the effects of microwave irradiation and thermal treatment on the dynamic compression and fragmentation properties of rocks is essential to quantify energy consumption in rock engineering.In this study,F... Understanding the effects of microwave irradiation and thermal treatment on the dynamic compression and fragmentation properties of rocks is essential to quantify energy consumption in rock engineering.In this study,Fangshan granite(FG)specimens were exposed to microwave irradiation and heat treatment.The damage of FG specimens induced by these two methods was compared using X-ray CT scanning and ultrasonic wave method.The temperatures of FG after microwave irradiation and thermal treatment were effectively evaluated using a newly proposed technique.A novelty method for precisely determining the geometric features of fragments is developed to estimate the fragmentation energy.Thus,the dynamic uniaxial compressive strength(UCS),the dynamic fragmentation characteristics,and the fragmentation energy of FG after these two pretreatment methods can be reasonably compared.The noticeable distinction of loading rate effect on the dynamic UCS of FG between these two pretreatment methods is first observed.A relationship is established between the dynamic UCS and the damage induced by microwave irradiation and heat treatment.Moreover,fragmentation energy fan analysis is introduced to accurately compare the fragmentation properties of FG after two pretreatment methods in dynamic compression tests. 展开更多
关键词 Fangshan granite Dynamic experiments Microwave irradiation Thermal treatment Loading rate fragmentATION
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Progressive fragmentation of granular assemblies within rockslides: Insights from discrete-continuous numerical modeling
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作者 JIANG Hui ZHOU Yuande +2 位作者 WANG Jinting DU Xiuli HUANG Hailong 《Journal of Mountain Science》 SCIE CSCD 2024年第4期1174-1189,共16页
Rock fragmentation plays a critical role in rock avalanches,yet conventional approaches such as classical granular flow models or the bonded particle model have limitations in accurately characterizing the progressive... Rock fragmentation plays a critical role in rock avalanches,yet conventional approaches such as classical granular flow models or the bonded particle model have limitations in accurately characterizing the progressive disintegration and kinematics of multi-deformable rock blocks during rockslides.The present study proposes a discrete-continuous numerical model,based on a cohesive zone model,to explicitly incorporate the progressive fragmentation and intricate interparticle interactions inherent in rockslides.Breakable rock granular assemblies are released along an inclined plane and flow onto a horizontal plane.The numerical scenarios are established to incorporate variations in slope angle,initial height,friction coefficient,and particle number.The evolutions of fragmentation,kinematic,runout and depositional characteristics are quantitatively analyzed and compared with experimental and field data.A positive linear relationship between the equivalent friction coefficient and the apparent friction coefficient is identified.In general,the granular mass predominantly exhibits characteristics of a dense granular flow,with the Savage number exhibiting a decreasing trend as the volume of mass increases.The process of particle breakage gradually occurs in a bottom-up manner,leading to a significant increase in the angular velocities of the rock blocks with increasing depth.The simulation results reproduce the field observations of inverse grading and source stratigraphy preservation in the deposit.We propose a disintegration index that incorporates factors such as drop height,rock mass volume,and rock strength.Our findings demonstrate a consistent linear relationship between this index and the fragmentation degree in all tested scenarios. 展开更多
关键词 Rock fragmentation ROCKSLIDE Numerical modelling Discrete-continuous modelling RUNOUT Cohesive zone model
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Effects of landscape fragmentation of plantation forests on carbon storage in the Loess Plateau,China
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作者 LEI Hangyu DUAN Dantong +3 位作者 CHEN Yi GUO Huifeng LI Jiangtao LI Xiang 《Journal of Arid Land》 SCIE CSCD 2024年第2期266-281,共16页
Tree plantation and forest restoration are the major strategies for enhancing terrestrial carbon sequestration and mitigating climate change.The Grain for Green Project in China has positively impacted global carbon s... Tree plantation and forest restoration are the major strategies for enhancing terrestrial carbon sequestration and mitigating climate change.The Grain for Green Project in China has positively impacted global carbon sequestration and the trend towards fragmentation of plantation forests.Limited studies have been conducted on changes in plantation biomass and stand structure caused by fragmentation,and the effect of fragmentation on the carbon storage of plantation forests remains unclear.This study evaluated the differences between carbon storage and stand structure in black locust forests in fragmented and continuous landscape in the Ansai District,China and discussed the effects of ecological significance of four landscape indices on carbon storage and tree density.We used structural equation modelling to explore the direct and indirect effects of fragmentation,edge,abiotic factors,and stand structure on above-ground carbon storage.Diameter at breast height(DBH)in fragmented forests was 53.3%thicker,tree density was 40.9%lower,and carbon storage was 49.8%higher than those in continuous forests;for all given DBH>10 cm,the trees in fragmented forests were shorter than those in continuous forests.The patch area had a negative impact on carbon storage,i.e.,the higher the degree of fragmentation,the lower the density of the tree;and fragmentation and distance to edge(DTE)directly increased canopy coverage.However,canopy coverage directly decreased carbon storage,and fragmentation directly increased carbon storage and tree density.In non-commercial forests,fragmentation reduces the carbon storage potential of plantation,and the influence of patch area,edge,and patchy connection on plantation should be considered when follow-up trees are planted and for the plantation management.Thus,expanding the area of plantation patches,repairing the edges of complex-shaped patches,enhancing the connectivity of similar patches,and applying nutrients to plantation forests at regular intervals are recommended in fragmented areas of the Loess Plateau. 展开更多
关键词 landscape fragmentation PLANTATION carbon storage tree allometry tree density structural equation modelling
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The Impacts and Causes of Land Fragmentation on Farm Productivity: Case Review of East African Countries
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作者 Joseph Mayindo Mayele Jacob B. Kolleh Joel Emmanuel Saburi 《Open Journal of Ecology》 2024年第5期455-482,共28页
This report provides an overall assessment of land fragmentation problems in East Africa. Many parts of East Africa have become highly fragmented, putting development systems and activities in these areas at risk of c... This report provides an overall assessment of land fragmentation problems in East Africa. Many parts of East Africa have become highly fragmented, putting development systems and activities in these areas at risk of complete collapse. Land fragmentation occurs when land gets converted for agriculture, industrialization, or urbanization, invaded by non-local plants, or enclosed for individual use and by subdividing farmlands into subsequent smaller units called parcels with varying average farm sizes. Fragmentation results from inappropriate agricultural development processes and ineffective land use planning that fails to recognize how farmland is used, and the importance of its interconnected areas. Insecurity of tenure and resource rights are key factors in making this possible. Land fragmentation is one of the key reasons why the ability of most resources in East Africa becomes scarcer, and those remaining become “privatized” by more powerful community members—keen to maintain their access to them. Such individualistic attitudes are new and disadvantage the poorest even further by affecting the traditional customary safety nets and agricultural outputs. Neither the government nor customary governance systems effectively protect resource access for the poorest. This review summary report identifies the key causes, measures, and implications, government interventions, and the common remedies to land fragmentation problems in the East African Countries of Kenya, Uganda, Rwanda, and Tanzania including neighboring Ethiopia, and the Sudan. The findings indicated from 2005 to 2015, the population kept increasing for all the named countries in East Africa with Rwanda and Uganda having a substantial increase in population density. The study review further explores the trend in the performance of agriculture by average farm sizes within the intervals of five years by highlighting their strong linkages and found that the average farm size has declined drastically, especially for Kenya. This can only mean that small farms kept becoming smaller and smaller and that there were more small-scale farmers. The results further depicted that the major and commonly cultivated food crops among the East African countries include maize, sorghum, rice, cassava, sweet potatoes, bananas, Irish potatoes, beans, peas, etc., with maize yields (Mt/ha) in 2003 for Uganda being the highest (1.79 Mt/ha) and the lowest in Rwanda (0.77 Mt/ha) respectively. Therefore, from the review results, recommendations are being made as to how the negative impacts of land fragmentation on agricultural productivity can be reduced or mitigated. One way is by community sensitization and awareness about the importance of land consolidation and its proposition on farm productivity. 展开更多
关键词 Land fragmentation Land Consolidation Farm Productivity INDUSTRIALIZATION Impacts CAUSES Average Farm Size Population East Africa
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Research on the Evolution Structure of Fragment Disordering Public Opinion in College Students’ Network Circle Group
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作者 Huawei Zhi Yan Qiao 《Social Networking》 2024年第4期45-65,共21页
Clarifying the evolution structure of public opinion induced and spread by fragmentation in college students’ network circle group is the key to understanding college students’ online social psychological demands, g... Clarifying the evolution structure of public opinion induced and spread by fragmentation in college students’ network circle group is the key to understanding college students’ online social psychological demands, grasping the development trend of public opinion, and designing targeted public opinion governance strategies. On the basis of identifying the key variables in the process of public opinion communication, DEMATEL-ISM model is used to explore the attribute positioning, relative importance level and hierarchical association mechanism of ante-variable and result variable, and then the governance strategies for fragment disordering public opinion in network circle groups of college students is designed. According to the study, exogenous stimuli, the uniqueness of discourse system, the number of spectacular texts and micro-narrative mode constituted the deep-rooted causes of fragment disordering public opinion. The unique situational and information attributes of network circle groups often become an important “booster” of disordered public opinion. The topic deviation is often accompanied with the formation of negative emotions. The corresponding public opinion governance strategies are sought from the aspects of shaping the network environment, adjusting the operation mechanism of the network circle group, improving the efficiency of using fragmented information, and optimizing the human resources of colleges. 展开更多
关键词 College Students’ Network Circle Group fragment Disordering Public Opinion Governance DEMATEL ISM
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A possible probe to neutron-skin thickness by fragment parallel momentum distribution in projectile fragmentation reactions
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作者 Chun-Wang Ma Yi-Jie Duan +5 位作者 Ya-Fei Guo Chun-Yuan Qiao Yu-Ting Wang Jie Pu Kai-Xuan Cheng Hui-Ling Wei 《Nuclear Science and Techniques》 SCIE EI CAS CSCD 2024年第6期114-119,共6页
Neutron-skin thickness is a key parameter for a neutron-rich nucleus;however,it is difficult to determine.In the framework of the Lanzhou Quantum Molecular Dynamics(LQMD)model,a possible probe for the neutron-skin thi... Neutron-skin thickness is a key parameter for a neutron-rich nucleus;however,it is difficult to determine.In the framework of the Lanzhou Quantum Molecular Dynamics(LQMD)model,a possible probe for the neutron-skin thickness(δ_(np))of neutron-rich ^(48)Ca was studied in the 140A MeV ^(48)Ca+^(9)Be projectile fragmentation reaction based on the parallel momentum distribution(p∥)of the residual fragments.A Fermi-type density distribution was employed to initiate the neutron density distributions in the LQMD simulations.A combined Gaussian function with different width parameters for the left side(Γ_(L))and the right side(Γ_(R))in the distribution was used to describe the p∥of the residual fragments.Taking neutron-rich sulfur isotopes as examples,Γ_(L) shows a sensitive correlation withδ_(np) of ^(48)Ca,and is proposed as a probe for determining the neutron skin thickness of the projectile nucleus. 展开更多
关键词 Neutron-skin thickness Projectile fragmentation Parallel momentum distribution Neutron-rich nucleus Quantum molecular dynamics model
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