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Clinical characteristics of testicular torsion and factors influencing testicular salvage in children:A 12-year study in tertiary center
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作者 Xiang-Hui Gang Yuan-Yuan Duan +5 位作者 Bin Zhang Zheng-Gan Jiang Rong Zhang Jun Chen Xiang-Yu Teng Duo-Bing Zhang 《World Journal of Clinical Cases》 SCIE 2024年第7期1251-1259,共9页
BACKGROUND Testicular torsion is the most common acute scrotum worldwide and mainly occurs in children and adolescents.Studies have demonstrated that the duration of symptoms and torsion grade lead to different outcom... BACKGROUND Testicular torsion is the most common acute scrotum worldwide and mainly occurs in children and adolescents.Studies have demonstrated that the duration of symptoms and torsion grade lead to different outcomes in children diagnosed with testicular torsion.AIM To predict the possibility of testicular salvage(TS)in patients with testicular torsion in a tertiary center.METHODS We reviewed the charts of 75 pediatric patients with acute testicular torsion during a 12-year period from November 2011 to July 2023 at the Suzhou Hospital of Anhui Medical University.Univariate and multivariate logistic regression analyses were used to determine independent predictors of testicular torsion.The data included clinical findings,physical examinations,laboratory data,color Doppler ultrasound findings,operating results,age,presenting institution status,and follow-up results.RESULTS Our study included 75 patients.TS was possible in 57.3%of all patients;testicular torsion occurred mostly in winter,and teenagers aged 11-15 years old accounted for 60%.Univariate logistic regression analyses revealed that younger age(P=0.09),body mass index(P=0.004),torsion angle(P=0.013),red blood cell count(P=0.03),neutrophil-to-lymphocyte ratio(P=0.009),and initial presenting institution(P<0.001)were associated with orchiectomy.In multivariate analysis,only the initial presenting institution predicted TS(P<0.05).CONCLUSION The initial presenting institution has a predictive value for predicting TS in patients with testicular torsion.Children with scrotal pain should be admitted to a tertiary hospital as soon as possible. 展开更多
关键词 testicular torsion testicular salvage PEDIATRICS PREDICTORS Case report
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Blood perfusion of the contralateral testis evaluated with contrast-enhanced ultrasound in rabbits with unilateral testicular torsion 被引量:10
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作者 Lin Chen Wei-Wei Zhan +7 位作者 Zhou-Jun Shen Wen-Bin Rui Chen Lv Man Chen Jian-Qiao Zhou Ping Zhou Mi Zhou Ying Zhu 《Asian Journal of Andrology》 SCIE CAS CSCD 2009年第2期253-260,共8页
The changes of blood perfusion of contralateral testis after unilateral testicular torsion remain controversial.In this study,28 New Zealand white male rabbits were randomly divided into five groups.Group A(n=8),the c... The changes of blood perfusion of contralateral testis after unilateral testicular torsion remain controversial.In this study,28 New Zealand white male rabbits were randomly divided into five groups.Group A(n=8),the control group,underwent a sham operation on the unilateral testis without inducing testicular torsion.In groups B,C,and D(n=5 each),unilateral testicular torsion was induced,and,after 3,6 or 24 h,respectively,detorsion was performed.In group E(n=5),permanent unilateral testicular torsion was applied.Contrast-enhanced ultrasound was used to observe the blood perfusion of the contralateral testis at the following stages:pre-torsion(preopration),immediately post-torsion(postopration),pre-detorsion,immediately post-detorsion,and late-stage post-detorsion(6-12 h post-detorsion in groups B-D)or at a similar time point(15-21 h post-torsion in group E).Time-intensity curves were generated,and the following parameters were derived and analyzed:arrival time,time to peak intensity,peak intensity,and half-time of the descending peak intensity.The analysis revealed that blood perfusion of the contralateral testis increased immediately after testicular torsion on the opposite side(P<0.05),which increased with prolonged testicular torsion of the other testis.This research demonstrated that contrast-enhanced ultrasound was valuable in evaluating blood perfusion of the contralateral testis after unilateral testicular torsion. 展开更多
关键词 contrast-enhanced ultrasound RABBITS testicular torsion
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Single intratesticular injection of blood-serum-derived exosomes can potentially alleviate testopathy following testicular torsion 被引量:3
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作者 Mona Keivan Fatemeh Mansouri Torghabeh +2 位作者 Samira Davoodi Shima Moradi Maryamneghari Reza Dadfar 《Animal Models and Experimental Medicine》 CAS CSCD 2022年第4期362-368,共7页
Background:Testicular torsion(TT)is an acute inflammatory process leading to male infertility.Today,anti-i nflammatory effects of exosomes derived from blood serum are used in various laboratory procedures.In the pres... Background:Testicular torsion(TT)is an acute inflammatory process leading to male infertility.Today,anti-i nflammatory effects of exosomes derived from blood serum are used in various laboratory procedures.In the present study,the anti-i nflammatory effects of blood-serum-derived exosomes in treatment of acute inflammation following TT in mice were evaluated.Materials and Methods:Eighteen male mice were grouped as healthy control,TT,and TT+exosome.TT was induced surgically,and exosomes were extracted from blood serum and administrated by a single intratesticular injection(10 IU).Malondialdehyde(MDA)and Griess assays were used to evaluate the level of oxidative stress.Sperm indices,testosterone(Tes),and apoptotic gene expression(p-53,Bcl2,and Caspase-3)were also assessed.H&E and immunohistochemistry(IHC)stainings were used for histopathological investigations.Data analysis was applied by SPSS(v.19)software.Results:Oxidative stress and apoptotic genes expression were increased significantly(p<0.05)in TT group compared with control.Sperm parameters and Tes were significantly increased,and expression of apoptotic genes was significantly reduced in TT+exosome group(p<0.05).Conclusion:Since the blood-serum-derived exosomes have anti-i nflammatory features,the intratesticular application of blood-serum-derived exosomes can be used clinically in acute phase of orchitis following TT to inhibit testicular inflammation. 展开更多
关键词 anti-i nflammation EXOSOME parameter SPERM testicular torsion
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Clinical evaluation of testicular torsion presenting with acute abdominal pain in young males 被引量:3
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作者 Fujun Wang Zengnan Mo 《Asian Journal of Urology》 CSCD 2019年第4期368-372,共5页
Objective:To evaluate the features of testicular torsion presenting with acute abdominal pain and to raise awareness of testicular torsion with specific symptoms.Methods:From October 2005 to June 2016,nine patients wi... Objective:To evaluate the features of testicular torsion presenting with acute abdominal pain and to raise awareness of testicular torsion with specific symptoms.Methods:From October 2005 to June 2016,nine patients with testicular torsion who presented with isolated acute abdominal pain rather than scrotal pain as their primary symptom were retrospectively reviewed.Data,including the age of patients,season at admission,initial medical history,external genital examination,emergency ultrasound findings,operative findings,duration of abdominal pain,complications,and follow-up results,were collected.Results:The average age of patients was 14 years(range 10-17 years).Seven patients whose genitals were not initially examined externally were misdiagnosed as having ordinary abdominal diseases.Surgical exploration revealed that all the involved testes necrotized,and orchidectomy was performed.In the other two patients,scrotal and testicular abnormalities were detected immediately on admission,and emergency surgical exploration determined that the involved testis remained vital,so orchiopexy was performed.The mean duration from symptom onset to diagnosis was 4 h(3-5 h)in the orchiopexy group and 37 h(18-72 h)in the orchidectomy group.Six patients were psychologically affected during postoperative follow-up.Neither recurrence of testicular torsion nor testicular atrophy was recorded.Conclusion:Acute abdominal pain can be the initial and sole symptom of testicular torsion in young males.Physicians should pay close attention to the specific clinical presentation of testicular torsion. 展开更多
关键词 Acute abdominal pain testicular torsion Young males Initial symptom Retrospective analysis
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Ultrasound heterogeneity as an indicator of testicular salvage in testicular torsion: A single center experience 被引量:1
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作者 Omran Hasan Mohamed Mubarak +6 位作者 S.Mohamed Jawad Alwedaie Hasan Baksh Husain Alaradi Ameer Alarayedh Ali Alaradi Abdolsalam Ahmadi Akbar Jalal 《Asian Journal of Urology》 CSCD 2022年第1期57-62,共6页
Objective:Testicular torsion is a common urological emergency,mainly in the younger population.Our aim is to evaluate the efficacy and value of testicular echogenicity in predicting testicular viability.Methods:Patien... Objective:Testicular torsion is a common urological emergency,mainly in the younger population.Our aim is to evaluate the efficacy and value of testicular echogenicity in predicting testicular viability.Methods:Patients who were older than 13 years of age and were discharged with the diagnosis of testicular torsion were reviewed.Data obtained included demographic data,history,physical examination results,ultrasound findings including size,color Doppler flow,and echotexture,torsion degrees,and surgical procedure.In addition,the histopathological findings of patients who underwent orchiectomy were reviewed.Results:A total of 71 cases were diagnosed with testicular torsion between January 2016 to December 2018.The mean age at presentation was 20.4±7.0 years.The average time from the onset of pain until the presentation was 36.0±55.1 h.Out of the 71 ultrasound scans reviewed,45.1%showed homogenous echotexture and 54.9%showed heterogeneous echotexture of the affected testis.On scrotal exploration,the mean degree of torsion was 475.7±301.8 degrees;66.2%of the patients had a viable testis;and bilateral orchidopexy was done.The remaining 33.8%had a non-viable testis.Homogenous echotexture was after an average of 13.5 h of scrotal pain,while heterogeneous echotexture presented after 53.7 h of scrotal pain.There was a statistically significant difference between the time of presentation and echotexture changes on scrotal ultrasonography(p<0.01).The relationship between echotexture changes and testicular viability was statistically significant as well(p<0.001).Conclusion:A long time since the onset of pain coupled with heterogeneous changes in testicular parenchyma is a good indicator of non-viability.However,we still advocate for surgical exploration as the gold standard in diagnosis and management. 展开更多
关键词 TESTIS testicular torsion ORCHIOPEXY ORCHIECTOMY ULTRASOUND Echotexture
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Emergency Treatment of Testicular Torsion and Postoperative Follow-up: A 71 Case Report
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作者 潘峰 朱朝晖 +3 位作者 李兵 庞自力 肖亚军 曾甫清 《Journal of Huazhong University of Science and Technology(Medical Sciences)》 SCIE CAS 2012年第5期704-706,共3页
This study presented our experience in the treatment of testicular torsion,which may help achieve early diagnosis and improve therapeutic effects.A retrospective analysis was conducted in 71 patients with testicular t... This study presented our experience in the treatment of testicular torsion,which may help achieve early diagnosis and improve therapeutic effects.A retrospective analysis was conducted in 71 patients with testicular torsion who were treated in our hospital from October 2007 to April 2011.The age of the patients ranged from 16 days to 34 years.All the patients had unilateral testicular torsion,which took place on the left side in 43 cases and on the right side in 28 cases.The course of the disease varied between three hours to 30 days.Post-operative follow-up was conducted until October 2011.Items examined included signs and symptoms at their first clinical visit,ultrasound findings,treatment in emergency surgery,and post-operative follow-up.In this study,the 71 patients were diagnosed with testicular torsion by color Doppler sonography,7 had testicular fixation,63 patients received orchiectomy,while 1 patient did not undergo surgery due to pressure from family members.Post-operative follow-up showed that the one patient’s testicle,which had been reserved,atrophied,while all the other survived.No recurrence was found during the follow-up visits.It is concluded that an early diagnosis and surgery is important in improving the survival rate of testicular torsion,and the diagnosis and treatment by the first attending clinician is of critical importance. 展开更多
关键词 testicular torsion emergency treatment post-operative follow-up
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Improving testicular examinations on paediatric patients in the emergency department:A quality improvement study to improve early diagnosis of testicular torsion
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作者 Ernest M.Cheng Juanita N.Chui +1 位作者 Murray Crowe Andrew Cooke 《Asian Journal of Urology》 CSCD 2022年第2期152-156,共5页
Objective:Male paediatric patients presenting with abdominal and/or testicular pain are common in the emergency department.As a time-sensitive diagnosis,the importance of early recognition,referral,and definitive mana... Objective:Male paediatric patients presenting with abdominal and/or testicular pain are common in the emergency department.As a time-sensitive diagnosis,the importance of early recognition,referral,and definitive management is critical.Missed or delayed diagnoses and management of testicular torsion can result in significant long-term sequelae including impaired fertility and psychological burden.In this quality improvement study,we utilised educational posters aiming to improve awareness of testicular torsion as a differential for abdominal pain and therefore,improve the quality of testicular examinations performed in the emergency department.Methods:Observational pre-and post-intervention study was conducted at a tertiary hospital emergency department.A pre-interventional retrospective review of the electronic medical records was conducted.All male patients under 16-years-old presenting with“abdominal pain”or“testicular problem”were included.We assessed the rate of testicular examination and the quality of the examination based on four domains:Cremasteric reflex,lie,swelling,and hardness.Educational posters targeting both patients and clinicians were placed around the emergency department.Subsequent review of the electronic medical records post-intervention was performed assessing the same domains.Results:A total of 235 presentations were analysed with 124 in the pre-intervention group and 111 in the post-intervention group.Overall rate of documented testicular examinations increased by 14%(p=0.032).The quality of testicular examinations also improved from an average of 0.85 domains documented to 2.29 post-intervention(p<0.001).Subgroup analysis found doctors in training had a greater improvement in both rate and quality of documented testicular examination.Conclusion:Our study demonstrated the value of continuing education in promoting awareness of testicular torsion in the emergency department.We found a clear improvement in the quality of clinical documentation of a time-sensitive condition which may infer a decreased risk of missed and delayed diagnosis of testicular torsion. 展开更多
关键词 testicular torsion testicular examination Emergency department Quality improvement Urological emergency
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Evaluation of the neutrophil-lymphocyte ratio, platelet-lymphocyte ratio and monocyte lymphocyte ratio for diagnosis of testicular torsion
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作者 Cihan Bedel Mustafa Korkut 《Journal of Acute Disease》 2020年第5期213-217,共5页
Objective:To explore the value of complete blood count(CBC),including neutrophil-lymphocyte ratio(NLR),platelet-lymphocyte ratio(PLR),and monocyte lymphocyte ratio(MLR)in diagnosis of testicular torsion(TT)and differe... Objective:To explore the value of complete blood count(CBC),including neutrophil-lymphocyte ratio(NLR),platelet-lymphocyte ratio(PLR),and monocyte lymphocyte ratio(MLR)in diagnosis of testicular torsion(TT)and differential diagnosis from epididymo-orchitis.Methods:The study was conducted at the Antalya Training and Research Hospital Emergency Department in Turkey with acute scrotal pain patients from January 1st,2016 to January 1st,2018.The patients were categorized into 3 groups:the TT group who underwent an operation for TT(n=70),the epididymo-orchitis group who received epididymo-orchitis treatment(n=120),and the healthy control group(n=100).NLR,PLR,and MLR of the three groups were analysed and compared.The optimum cut-off values of NLR,MLR,and PLR were analyzed.Results:Mean NLR and MLR values were significantly higher in the epididymo-orchitis group and the TT group compared to the control group(P<0.001).Receiver operating characteristic analysis revealed a sensitivity of 77.1%and a specificity of 80%for NLR(77.1)and a sensitivity of 68.2%and a specificity of 78%for PLR(124.80).Moreover,when MLR was used to differentiate the two treatment groups,the optimal cut-off value had a sensitivity of 67.1%and a specificity of 75%(AUC:0.677-0.826,P<0.001).Conclusions:NLR,PLR,and MLR might be associated with the diagnosis of TT.These parameters provide a useful and economical method to help diagnose TT in the emergency department. 展开更多
关键词 testicular torsion EPIDIDYMO-ORCHITIS Monocyte lymphocyte ratio Emergency department
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Perinatal testicular torsion—An emergency with grave consequences
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作者 Dietrich Doll Josef Erkel +1 位作者 Thomas Erhart Christian Honemann 《Case Reports in Clinical Medicine》 2013年第1期66-69,共4页
Introduction: Perinatal testicular torsion is not a frequent, but a grave finding finding. As only immediate surgical retorsion may save the viability of the testicle, time is of essence. We report the case of a newbo... Introduction: Perinatal testicular torsion is not a frequent, but a grave finding finding. As only immediate surgical retorsion may save the viability of the testicle, time is of essence. We report the case of a newborn where delayed diagnosis led to an unnecessary loss of one testicle. Presentation of Case: The newborn was presented one day after delivery with a swollen left blue scrotal pouch. The left testicle was little tender, higher in position and enlarged. Ultrasound revealed a globular, enlarged testicle left, showing hypodense necrotic areas within. Doppler sound could not detect any perfusion of the spermatic vessels. Scrotal fluid was present bilaterally. At operation, the testicle was considered unsalvageable, and left orchiectomy and right orchidopexy were performed. Discussion: In the new-born, it is more than convenient to perfom ultrasound of both testicles at the same time, which allows to compare texture and perfusion easily. Immediate surgical exploration should be performed at any time, even if in diagnostic doubt. The very most important step though is to professionally recognise and to react to this pediatric emergency, as time is of paramount essence. Conclusion: A case of a male newborn with unilateral perinatal testicular torsion is presented, where typical clinical signs and ultrasound features can be seen. Early exploration with orchiectomy of the necrotic testicle and orchidopexy of the healthy side may save the endocrine function and fertility. 展开更多
关键词 Neonatal PERINATAL testicular torsion testicular Necrosis ORCHIDOPEXY Acute Scrotal Swelling
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Clinical Findings of Patients Undergone Surgery for Testicular Torsion: A 12-Year Single Center Experience in Northern Iran 被引量:2
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作者 Hamid Shafi Amin Zarghami +1 位作者 Arsalan Aliramaji Maryam Rahimi 《Open Journal of Urology》 2014年第5期63-69,共7页
Introduction: Testicular torsion is a surgical emergency which requires early diagnosis and prompt surgical management to avoid testicular damage. The aim of this study is to survey the clinical findings and outcome o... Introduction: Testicular torsion is a surgical emergency which requires early diagnosis and prompt surgical management to avoid testicular damage. The aim of this study is to survey the clinical findings and outcome of the patients treated for testicular torsion in a university hospital in Babol, northern Iran. Methods: In this cross sectional study, a retrospective survey of all cases presenting with acute scrotum and primarily diagnosed as testicular torsion was conducted during 2001 and 2012 in Babol, northern Iran. All 103 cases were reviewed and several clinical data, including duration of symptoms and operative findings were collected. Findings: Of 103 patients who presented to the emergency department with acute scrotum, the median age of the cases was 16.0 years. Thirty four percent of the patients presented emergency unit less than 6 hours from symptom exposure. Pain (95.1%) was the major symptom in all patients. Surgery revealed that 72 (70.9%) cases were diagnosed firmly as testicular torsion that 23 patients underwent orchidectomy for a necrotic torsed testis. There were significant differences between orchiectomized versus non-orchiectomized torsion cases in affected side, symptom presentation to operation time. Conclusion: According to our results more than half of the cases presented more than in the golden time. Late presentation to hospital was the major cause of delay leading to orchidectomy in patients with testicular torsion. Greater effort in health education and direct or selfreferal to hospital may reduce this delay. 展开更多
关键词 testicular torsion ORCHIDECTOMY ORCHIOPEXY
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Comparison of quercetin and resveratrol in the prevention of injury due to testicular torsion/ detorsion in rats 被引量:1
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作者 Kai-Kai Chi Wen-Hui Zhang +6 位作者 Zhu Chen Yong Cui Wei He Suo-Gang Wang Chan Zhang Jie Chen Guang-Ce Wang 《Asian Journal of Andrology》 SCIE CAS CSCD 2016年第6期908-912,共5页
Quercetin (QE) and resveratrol (RSV) are powerful antioxidants with the potential to protect the testes against ischemia/reperfusion (I/R) injury. We compared their effects in testicular torsion/detorsion (T/D... Quercetin (QE) and resveratrol (RSV) are powerful antioxidants with the potential to protect the testes against ischemia/reperfusion (I/R) injury. We compared their effects in testicular torsion/detorsion (T/D) in adult rats. Twenty-four male Wistar rats were divided into four groups: sham (group A), T/D (group B), T/D treated with QE (group C), and T/D treated with RSV (group D). QE (20 mg kg-1) and RSV (20 mg kg-1) were injected intra-peritoneally at 60 min of torsion. After 90 rain of surgically induced torsion, the testicular cord was restored to its anatomical position. Twenty-four hour after torsion, blood and tissue samples were obtained for further examination. Testicular tissue malondialdehyde (MDA) and nitric oxide (NO) levels and serum total oxidant status (TOS) were higher in group B than in group A (P 〈 0.05). Group A had higher serum total antioxidant status (TAS) than group B. (P 〈 0.05) QE and RSV significantly lowered MDA, NO, and TOS levels and TAS consumption (P 〈 0.05). QE reduced the MDA and TOS levels more than RSV (P〈 0.05), but their effects on NO reduction and TAS consumption were similar (P〉 0.05). Group A had normal testicular architecture (grade 1). Groups C (mean grade 2.60) and D (mean grade 3.00) had lower testicular injury grades than group B (mean grade 3.45) (P 〈 0.05). Group C had lower testicular injury grade than group D (P 〈 0.05). Treatment with QE and RSV protects against I/R injury after testicular T/D. QE may exhibit better function than RSV at the doses tested in this study. 展开更多
关键词 ISCHEMIA/REPERFUSION QUERCETIN RAT RESVERATROL testicular torsion/detorsion
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Long-term follow-up results of testicular torsion in children 被引量:1
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作者 Cheng-Jun Yu Jie Zhao +8 位作者 Jin Luo Yi-Fan Hong Tian-Xin Zhao Sheng Wen Li Jiang Tao Lin Da-Wei He Guang-Hui Wei Sheng-De Wu 《Asian Journal of Andrology》 SCIE CAS CSCD 2022年第6期653-659,共7页
December 2020 to investigate the long-term follow-up results after testicular torsion(TT)in children.Boys with TT were divided into the salvage orchiopexy group and the orchiectomy group,and the baseline characteristi... December 2020 to investigate the long-term follow-up results after testicular torsion(TT)in children.Boys with TT were divided into the salvage orchiopexy group and the orchiectomy group,and the baseline characteristics,ultrasonographic indications,intraoperative findings,testicular volumes,and adverse events during follow-up were compared.A total of 145 cases were included in this study.Approximately 56.6%of patients who underwent salvage orchiopexy had testicular atrophy(TA),and the median testicular volume loss of the testes was 57.4%.Age less than 6 years,delayed surgery,and intraoperative poor blood supply were associated with TA in pediatric TT after orchiopexy.Most atrophied testes appeared within 3-6 months after surgery.Compared with the corresponding age-matched healthy controls,the contralateral testicular volumes were larger in the orchiopexy(P=0.o01 without TA,and P=0.042 with TA)and orchiectomy groups(P=0.033).The adverse events were comparable in patients with orchiectomy or orchiopexy.In summary,follow-up before 3 months after surgery may not offer sufficient clinical value,while that 3 months after surgery should be regarded as the first follow-up time for testicular monitoring.The contralateral testes of patients with TT showed compensatory hypertrophy.We suggest performing orchiectomy when torsed testes are surgically assessed as Arda gradeⅢor inviable. 展开更多
关键词 LONG-TERM ORCHIECTOMY PEDIATRICS salvage orchiopexy testicular torsion
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Cryptorchid testicular torsion in children characteristics and treatment outcomes 被引量:1
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作者 Hai-Jun Zhong Liang-Feng Tang Yun-Li Bi 《Asian Journal of Andrology》 SCIE CAS CSCD 2021年第5期468-471,共4页
This study aimed to review and compare the characteristics and treatment outcomes of cryptorchid testicular torsion in pre-and postpubertal children.We reviewed the clinical data of 22 patients with testicular torsion... This study aimed to review and compare the characteristics and treatment outcomes of cryptorchid testicular torsion in pre-and postpubertal children.We reviewed the clinical data of 22 patients with testicular torsion complicated by cryptorchidism who were treated between January 2010 and December 2019.Patients were categorized into prepubertal(1 month to 9 years;n=12)and postpubertal groups(10-16 years;n=10).The age at presentation,clinical presentations,physical examination,and operation outcomes were assessed.The common clinical presentations in both groups were inguinal pain and a tender inguinal mass.Patients in the prepubertal group were significantly more likely to present with restlessness(33.3%)than those in the postpubertal group(0%;P-0.044).After detorsion,testicular blood flow recovered during surgery in 25.0%of the prepubertal and 80.0%of the postpubertal patients(P=0.010).Orchiectomy was required in 50.0%of the prepubertal and 20.0%of the postpubertal patients(P=0.145).Of the 22 patients with follow-up data,the rates of testicular salvage were significantly different,at 16.7%in the prepubertal patients and 60.0%in the postpubertal patients(P=0.035).Cryptorchid testicular torsion has various manifestations.Although an empty hemiscrotum and a painful groin mass were common in both groups,restlessness was more prevalent in the prepubertal patients during early testicular torsion onset than that in the postpubertal patients.Notably,the testicular salvage rate was significantly lower in the prepubertal patients than that in the postpubertal patients. 展开更多
关键词 CHILDREN CRYPTORCHIDISM testicular torsion
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Establishment and internal validation of preoperative nomograms for predicting the possibility of testicular salvage in patients with testicular torsion 被引量:1
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作者 Wan-Xiang Zheng Guang-Dong Hou +10 位作者 Wei Zhang Di Wei Xue-Lin Gao Mei-Hong Chen Lu-Guang Huang Fei Yan Geng Zhang Lei Yu Fei Liu Bo Zhang Jian-Lin Yuan 《Asian Journal of Andrology》 SCIE CAS CSCD 2021年第1期97-102,共6页
This study aimed to establish nomograms to preoperatively predict the possibility of testicular salvage(TS)in patients with testicular torsion.The clinical data of 204 patients with testicular torsion diagnosed at Xij... This study aimed to establish nomograms to preoperatively predict the possibility of testicular salvage(TS)in patients with testicular torsion.The clinical data of 204 patients with testicular torsion diagnosed at Xijing Hospital and Tangdu Hospital(Xi'an,China)between August 2008 and November 2019 were retrospectively analyzed.Univariate and multivariate logistic regression analyses were used to determine the independent predictors of TS.Based on multivariate regression coefficients,nomograms to predict possibility of TS were established.The predictive ability of the nomograms was internally validated by receiver operating characteristic(ROC)curves and calibration plots.The duration of symptoms ranged from 2 h to 1 month,with a median of 3.5 days.Thirty(14.7%)patients underwent surgical reduction and contralateral orchiopexy,while the remaining 174(85.3%)underwent orchiectomy and contralateral orchiopexy.Finally,long symptom duration was an independent risk predictor for TS,while visible intratesticular blood flow and homogeneous testicular echotexture under color Doppler ultrasound were independent protective predictors.Internal validation showed that the nomograms,which were established by integrating these three predictive factors,had good discrimination ability in predicting the possibility of TS(areas under the ROC curves were 0.851 and 0.828,respectively).The calibration plots showed good agreement between the nomogram-predicted possibility of TS and the actual situation.In conclusion,this brief preoperative prediction tool will help clinicians to quickly determine the urgency of surgical exploration. 展开更多
关键词 NOMOGRAM testicular salvage testicular torsion
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Collagen fleece(Tachosil®)for treating testis torsion:A case report
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作者 Ki Min Kim Jae Heon Kim 《World Journal of Clinical Cases》 SCIE 2023年第18期4306-4312,共7页
BACKGROUND Testicular torsion is an emergent disease in urology,and there has been discussion of the treatment of testicular torsion.Testicular decompression has been established as a critical treatment for testicular... BACKGROUND Testicular torsion is an emergent disease in urology,and there has been discussion of the treatment of testicular torsion.Testicular decompression has been established as a critical treatment for testicular compartment syndrome(TCS),which occurs after detorsion in a patient who is diagnosed with testis torsion.Until now,testicular fasciotomy and incision of tunica albuginea with tunica vaginalis flap(TVF)graft have been suggested for decompression,and some studies about the efficacy of TVF were reported.However,this method is time consuming and needs meticulous technique,so other methods such as orchio-septopexy are suggested.The objective of this clinical case report was to propose new surgical method using collagen fleece(Tachosil®)instead of tunica vagina flap.CASE SUMMARY A 5-year-old boy with scrotal pain visited our hospital 24 h after symptom onset.After history taking,physical examination,and scrotum ultrasonography,he was diagnosed with testis torsion.Emergency surgery was performed after diagnosis.Following the incision of scrotum and fasciotomy,we covered his tunica albuginea with collagen fleece called Tachosil®instead of covering with TVF.CONCLUSION Short-term follow-up showed normal blood flow in testis without a TCS.This is the first case report of using Tachosil®in testicular torsion surgery,and its advantages were already reported in other surgeries like Peyronie’s disease.Our case suggests this new technique is an appropriate method because of its advantages including its cost-effective and time-saving characteristics.The main limitation is the short follow-up,so more studies are needed to provide a high level of evidence about its efficacy and safety. 展开更多
关键词 testicular torsion testicular compartment syndrome Collagen fleece Tachosil® Case report
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Tsc1/Tsc2 complex: A molecular target of capsaicin for protection against testicular torsion induced injury in rats 被引量:1
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作者 Nasim Javdan Seyed Abdulmajid Ayatollahi +5 位作者 Muhammad Iqbal Choudhary Safaa Al-Hasani Farzad Kobarfard Kobra Mokhtarian Majid Khoshmirsafa Athar Ata 《Chinese Herbal Medicines》 CAS 2019年第2期216-221,共6页
Objective: The detailed knowledge about protective effects of capsaicin(cap) and involved mechanisms against testicular torsion(TT) is still not available completely.Methods: Male Wistar rats were assigned into four m... Objective: The detailed knowledge about protective effects of capsaicin(cap) and involved mechanisms against testicular torsion(TT) is still not available completely.Methods: Male Wistar rats were assigned into four major cohorts:(i) sham,(ii) TT,(iii) three subgroups subjected to TT and different doses of cap(100, 500, and 1000 μg/mL), and(iv) three subgroups of healthy animals subjected to various concentrations of cap. The animals were decapitated at 24 h after reperfusion, and the evaluation of protein expression was performed by Western blotting assay. At 72 h after reperfusion, apoptotic cell death and tissue injury were evaluated by TUNEL nuclear and H&E staining,respectively.Results: The results showed that cap administration following TT significantly increased the expression of tuberous sclerosis proteins 1 and 2(Tsc1/Tsc2) in a dose-dependent manner(P < 0.05). Cap decreased cell apoptosis at highest dose. Likewise, cap contributed to the preservation of tubular morphology and decreased tissue injury at the highest tested concentration(1000 μg/m L).Conclusion: Collectively, our findings demonstrate the validity of cap as a therapeutic agent against TT through targeting Tsc1/Tsc2 in a dose-dependent manner. 展开更多
关键词 CAPSAICIN cell SURVIVAL molecular TARGETS testicular torsion Tsc1/Tsc2 COMPLEX
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Torsion of the Spermatic Cord in Adults: Epidemiological, Diagnostic and Therapeutic Aspects Observed in 46 Patients at the Bouake Teaching Hospital
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作者 Ndiamoi Akassimadou Kouassi Patrice Avion +5 位作者 Brice Aguia Freddy Zouan Vénance Alloka Ben Sadia Kamara Romain Danho Koffi Dje 《Open Journal of Urology》 2023年第9期382-390,共9页
Introduction: Torsion of the spermatic cord (TSC) is a serious surgical emergency because it is responsible for acute ischemia that can lead to the loss of the testicle. Very few studies have been carried out in C?te ... Introduction: Torsion of the spermatic cord (TSC) is a serious surgical emergency because it is responsible for acute ischemia that can lead to the loss of the testicle. Very few studies have been carried out in C?te d’Ivoire and particularly in Bouaké, on torsion of the testicle. The general objective of this work was to describe the epidemiological, diagnostic and therapeutic aspects of testicular torsion in our context. Materials and Methods: This is a retrospective study on 46 patients received urgently at the Teaching Hospital of Bouaké over a period of nine (9) years from December 01, 2010 to November 30, 2019 for torsion of the spermatic cord in adults. Results: The mean age of patients was 26.6 years with extremes of 17 to 41 years. 33 patients were seen before the sixth hour and 13 beyond. Scrotal pain, swelling of the hemibursa and testicular ascent were the dominant physical signs. Orchiectomy + contralateral testicular fixation was performed in 11 patients (23.9%). The average length of hospital stay was three (3) days. The immediate post-operative follow-up was simple. Late complications were marked by two testicular atrophy. Conclusion: Our series was marked by a high rate of orchiectomy. Actions to raise caregivers’ awareness of the population must be carried out so that they consult quickly in front of any painful stock market board to avoid the delay in diagnosis and management detrimental to the vitality of the torsional testicle. 展开更多
关键词 torsion testicular Cord ORCHIECTOMY Ochidopexy ATROPHY
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环境温度与睾丸扭转发生的相关性分析研究
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作者 孟庆松 杜家兴 +7 位作者 张明 贾江华 汪鑫 张鹏 马万里 王亚轩 王东彬 齐进春 《中华男科学杂志》 CAS CSCD 2024年第2期128-131,共4页
目的:探讨环境温度是否为睾丸扭转发生的影响因素。方法:收集河北医科大学第二医院2013年12月至2020年12月确诊为睾丸扭转患者的具体临床数据。根据其发病时间在国家气象科学数据中心(http://data.cma.cn/)查询当天当地的气温。将其分为... 目的:探讨环境温度是否为睾丸扭转发生的影响因素。方法:收集河北医科大学第二医院2013年12月至2020年12月确诊为睾丸扭转患者的具体临床数据。根据其发病时间在国家气象科学数据中心(http://data.cma.cn/)查询当天当地的气温。将其分为0℃以下组、0~10℃组、10~20℃组、20℃以上组。根据各个分组睾丸扭转的发生数量,通过相关性分析,获得研究结果。结果:172例睾丸扭转患者中,发生率最高的温度区间是0~10℃组(35.5%)。12.8%的病例发生在0℃以下;34.9%的病例发生在10~20℃;16.9%的病例发生在20℃以上。不同温度区间睾丸扭转的发病率比较,差异有统计学意义(χ^(2)=29.07,P<0.001)。Spearman检验提示不同温度区间与睾丸扭转患病率呈负相关(r=-0.261,P<0.01)。不同季节之间发病率比较差异无统计学意义(χ^(2)=5.349,P>0.05),但睾丸扭转的发病仍主要集中在秋冬季。结论:睾丸扭转的患病率与环境温度之间存在负相关趋势,环境温度降低时,睾丸扭转的患者会相对增加。不同季节之间睾丸扭转发病率无明显差别,但睾丸扭转的发病仍主要集中在秋冬季,提示临床秋冬季时要更加注意睾丸扭转的诊治。 展开更多
关键词 睾丸扭转 环境温度 寒冷 季节 影响因素
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Management of the Torsion of Spermatic Cord in the Urology-Andrology Department of the Ignace Deen National Hospital in Conakry
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作者 Thierno Mamadou Oury Diallo Mamadou Bissiriou Bah +8 位作者 Mamadou Diawo Bah Boris Amougou Daouda Kanté Alimou Diallo Demba Cissé Abdoul Haqq Bah L’Imam Mamadou Dian Oury Diallo Abdoulaye Bobo Diallo Oumar Raphiou Bah 《Open Journal of Urology》 2023年第10期399-406,共8页
Introduction: Torsion of the spermatic cord is an emergency whose delay in treatment conditions the functional prognosis of the testicle. The aim of this study was to analyze the management of spermatic cord torsion i... Introduction: Torsion of the spermatic cord is an emergency whose delay in treatment conditions the functional prognosis of the testicle. The aim of this study was to analyze the management of spermatic cord torsion in the Urology Andrology Department of the Ignace Deen National Hospital in Conakry. Material and methods: This was a ten-year retrospective descriptive study from January 1, 2012 to December 31, 2021. It involved all patients admitted for torsion of the spermatic cord, confirmed at surgical exploration. Results: We identified 21 cases of torsion of the spermatic cord. The mean age of the patients was 17.9 ± 4.4 years. The average consultation time was 19.2 ± 21.4 hours with extremes of [2 h and 98 h]. Only 6 patients (28.6%) consulted before the sixth hour. All patients presented with scrotal swelling. At scrototomy, all torsions were intravaginal with two turns of spiral in 13 cases and three turns in 8 cases. Orchiectomy followed by contralateral orchidopexy was performed in 6 cases. In the other cases, bilateral orchidopexy was performed after detorsion. The average hospital stay was 4.5 days. We recorded 4 cases of testicular atrophy after orchidopexy. Conclusion: Spermatic cord torsion is an infrequent emergency in our department. The delay in consultation remains the main predictive factor of testicular necrosis. Emergency exploratory scrotomy should be the rule. 展开更多
关键词 Spermatic Cord torsion Delay in Consultation ORCHIDOPEXY ORCHIECTOMY testicular Atrophy
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中性粒细胞-淋巴细胞比值或可帮助术前预判急性阴囊疼痛患儿是否发生睾丸扭转
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作者 贺显雅 王晨 +11 位作者 杨勇军 陈俊杰 伍学成 李卓 刘哲 宋光庆 滕伊漓 陈佳 王洪卫 郑华义 李远伟 卢强 《现代泌尿外科杂志》 CAS 2024年第9期785-789,共5页
目的探讨应用中性粒细胞-淋巴细胞比值(NLR)预判急性阴囊疼痛患儿睾丸扭转(TT)的准确性。方法回顾性收集2017年1月—2024年1月于湖南省人民医院和洪江市人民医院接受住院治疗的158例术前超声诊断疑似为TT的患儿资料,所有患儿均急诊接受... 目的探讨应用中性粒细胞-淋巴细胞比值(NLR)预判急性阴囊疼痛患儿睾丸扭转(TT)的准确性。方法回顾性收集2017年1月—2024年1月于湖南省人民医院和洪江市人民医院接受住院治疗的158例术前超声诊断疑似为TT的患儿资料,所有患儿均急诊接受了睾丸探查手术。根据探查结果分为TT组(143例)和非TT组(15例)。分析两组患儿的临床资料、实验室检查和彩超检查结果,采用受试者工作特征(ROC)曲线分析NLR对TT诊断的敏感度和特异度。结果TT组和非TT组临床资料差异无统计学意义(P>0.05)。TT组NLR明显高于非TT组[(4.82±2.37)vs.(2.85±0.75),P<0.05]。NLR预测TT的最佳截断值为2.07,ROC曲线下面积(AUC)为0.809(95%CI:0.709~0.909),敏感度和特异度分别为97.9%、93.3%,显著高于其他因素。结论对于超声诊断疑似TT的急性阴囊疼痛患儿,NLR或可帮助预判是否发生TT,作为此类患儿临床治疗决策的重要参考指标。 展开更多
关键词 睾丸扭转 中性粒细胞-淋巴细胞比值 儿童 睾丸附睾炎
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