Aspirin,Ticlopidine(Ticlid),Clopidogrel(Plavix)三药都是抗血小板凝集的药物,临床常应用于血栓形成的预防及治疗。 Aspirin应用于临床已有百年历史,被誉为廿世纪的奇迹药物(wonder drug of the 20 th centruy)。自从1971年被证实它...Aspirin,Ticlopidine(Ticlid),Clopidogrel(Plavix)三药都是抗血小板凝集的药物,临床常应用于血栓形成的预防及治疗。 Aspirin应用于临床已有百年历史,被誉为廿世纪的奇迹药物(wonder drug of the 20 th centruy)。自从1971年被证实它有抗血小板凝集作用后,在脑血管意外疾病,心血管疾病,以及某些外周血管疾病治疗中,Aspirin一直作为传统药物用来预防血栓形成。它是非处方药物,价格便宜。 自从药物Ticlopidine和Clopidogrel出现后,展开更多
Eighty-two patients with supraventricular tachycardia undergoing radiofrequency catheter ablation (RFCA) were studied to observe the inhibition effect of aspirin and ticlopidine on platelet aggregability(PAG) and thro...Eighty-two patients with supraventricular tachycardia undergoing radiofrequency catheter ablation (RFCA) were studied to observe the inhibition effect of aspirin and ticlopidine on platelet aggregability(PAG) and thromboxane B2(TXB2) of the blood samples.Patients were divided into aspirin group A.ticlopidine group B.aspirin+ticlopidine group C and control group D.PAG and TXB2 were increased clearly after RFCA in all groups(P<0.001).Treatment with aspirin or ticlopidine before operation could reduce the patelet aggregability caused by RFCA and the joint effect of two drugs(change rate of group A:52.51±12.51%;group B:54.78±11.27%;group C:30.51±10.59%;group D:91.75±21.43%;(P<0.05)was studied .The much decreased platelet aggregability after antiplatelet therapy was evidence of the potential benefit of the treatment in preventing thromboembolism after ablation.Pretreatment with aspirin and ticlopidine together is a good way to decrease palateler aggregability after RFCA.展开更多
文摘Aspirin,Ticlopidine(Ticlid),Clopidogrel(Plavix)三药都是抗血小板凝集的药物,临床常应用于血栓形成的预防及治疗。 Aspirin应用于临床已有百年历史,被誉为廿世纪的奇迹药物(wonder drug of the 20 th centruy)。自从1971年被证实它有抗血小板凝集作用后,在脑血管意外疾病,心血管疾病,以及某些外周血管疾病治疗中,Aspirin一直作为传统药物用来预防血栓形成。它是非处方药物,价格便宜。 自从药物Ticlopidine和Clopidogrel出现后,
文摘Eighty-two patients with supraventricular tachycardia undergoing radiofrequency catheter ablation (RFCA) were studied to observe the inhibition effect of aspirin and ticlopidine on platelet aggregability(PAG) and thromboxane B2(TXB2) of the blood samples.Patients were divided into aspirin group A.ticlopidine group B.aspirin+ticlopidine group C and control group D.PAG and TXB2 were increased clearly after RFCA in all groups(P<0.001).Treatment with aspirin or ticlopidine before operation could reduce the patelet aggregability caused by RFCA and the joint effect of two drugs(change rate of group A:52.51±12.51%;group B:54.78±11.27%;group C:30.51±10.59%;group D:91.75±21.43%;(P<0.05)was studied .The much decreased platelet aggregability after antiplatelet therapy was evidence of the potential benefit of the treatment in preventing thromboembolism after ablation.Pretreatment with aspirin and ticlopidine together is a good way to decrease palateler aggregability after RFCA.
