AIM:To compare intraocular pressure(IOP)measured via the trans palpebral IOP(tp IOP)method using a Diaton or with a Goldman applanation tonometer(GAT)and study the determinants of IOP difference in eyes undergoing tra...AIM:To compare intraocular pressure(IOP)measured via the trans palpebral IOP(tp IOP)method using a Diaton or with a Goldman applanation tonometer(GAT)and study the determinants of IOP difference in eyes undergoing transepithelial photorefractive keratectomy(TPRK)for myopia.METHODS:This cross-sectional validation study was held in 2020 in an eye hospital in Saudi Arabia.IOP was measured by Diaton and GAT before treatment,after one week,and one month of TPRK.It is considered if IOP difference by Diaton and GAT was less than±2 mm Hg acceptable.The IOP difference was tested if correlated to spherical equivalent(SE),central corneal thickness(CCT),age,gender,or tp IOP.RESULTS:Totolly 200 myopic eyes of 100 patients were included in the study.The mean difference of IOP measured by two methods before TPRK,1wk,and 1mo after TPRK were 0.790,-0.790,and-0.920 mm Hg,respectively(P<0.001).Diaton could measure IOP effectively 89.5%eyes before TPRK and 82%and 84%at 1wk and 1mo after TPTK,respectively.At week 1,IOP differences were significantly correlated to baseline CCT(P=0.02)and tp IOP at week 1(P<0.001).One month after TPRK,only tp IOP was significantly correlated to the difference in IOP(P<0.001).CONCLUSION:Diaton is a good screening tool for IOP before TPRK.It helps in monitoring IOP after surgery.Although more practical,it is less efficient than GAT.In eyes with high myopia and low tp IOP before surgery,IOP post-TPRK by Diaton and GAT could differ.展开更多
目的:探究动态对比增强磁共振成像(dynamic contrast-enhanced magnetic resonance imaging,DCE-MRI)技术定量容积运转常数(Ktrans)、速率常数(K_(ep))指导肝脏肿块定性诊断的价值。方法:选取2018年1月—2022年12月期间苏州市相城区中...目的:探究动态对比增强磁共振成像(dynamic contrast-enhanced magnetic resonance imaging,DCE-MRI)技术定量容积运转常数(Ktrans)、速率常数(K_(ep))指导肝脏肿块定性诊断的价值。方法:选取2018年1月—2022年12月期间苏州市相城区中医医院收治的肝脏不明肿块患者共计92例,全部研究对象均接受DCE-MRI定量的Ktrans、K_(ep)检测,以组织病理学活检结果作为金标准,评估DCE-MRI定量的K^(trans)、K_(ep)检测应用于肝脏肿块定性诊断的价值。结果:在92例研究对象中,最终确诊为恶性病变者28例;非恶性病变者64例。两组研究对象的DCE-MRI检测结果显示,恶性病变组患者的Ktrans、K_(ep)水平均高于非恶性病变组,差异存在统计学意义(P<0.05);ROC曲线显示,DCE-MRI定量K^(trans)、K_(ep)应用于肝脏肿块定性检查的曲线下面积(AUC)分别为0.878、0.922,两项指标联合诊断的AUC为0.972。由此可见,K^(trans)、K_(ep)应用于肝脏肿块定性均具有较高的评估价值(P<0.05),且联合检测的评估效果优于单项检测。结论:DCE-MRI定量K^(trans)、K_(ep)应用于肝脏肿块定性均具有较高的评估价值,且联合检测的评估效果优于单项检测,值得借鉴应用。展开更多
Accurate spectroscopic data for H_(2)^(16)O in the 1.1μm region are particularly important for the study of Earth's atmosphere.The pure water vapor molecular spectra were measured based on direct laser absorption...Accurate spectroscopic data for H_(2)^(16)O in the 1.1μm region are particularly important for the study of Earth's atmosphere.The pure water vapor molecular spectra were measured based on direct laser absorption spectroscopy using a narrow line-width external cavity diode laser combined with a high-precision Fabry-Pérot etalon.A total of 31 H_(2)^(16)O transitions were studied for the first time by using the speed-dependent Nelkin-Ghatak profile and the Hartmann-Tran profile.From an accurate line-shape analysis,we obtained the line intensities and the self-broadening coefficients,and they are compared with the available data reported in the HITRAN 2016 database and the HITRAN 2020 database.Finally,we obtained information on the influence of Dicke narrowing,as well as the correlations between Dicke narrowing and speed dependence,and of speed-dependent effects.展开更多
Background: Accurate determination of gestational age has become important for deciding the appropriate time for termination of the pregnancy as well as to monitor the fetal growth during the entire period of pregnanc...Background: Accurate determination of gestational age has become important for deciding the appropriate time for termination of the pregnancy as well as to monitor the fetal growth during the entire period of pregnancy. Objective: The aim of the study was to assess whether the trans-cerebellar diameter, placental thickness or combining both of them is more accurate for assessment of gestational age in the 3<sup>rd</sup> trimester of pregnancy. Patients and Methods: This is a cross sectional study conducted at outpatient Clinic and Obstetric ward, Ain Shams University Maternity Hospital, over a period of six months from March 2019 to September 2019. One hundred pregnant women were recruited according to inclusion criteria either from outpatient clinic or were admitted in obstetric ward Ain Shams Maternity Hospital to find out the most accurate fetal biometric measurement in the third trimester either trans-cerebellar diameter placental thickness or both compared to reliable LMP (last menstrual period) dates confirmed by crown rump length (CRL) in the first trimester. Results: Trans-cerebellar diameter mean ± SD was 46.0 ± 3.5 with range 38.2 - 51.7. The mean of placental thickness was 39.6 ± 7.1 with range 22.8 - 54.3. Placental thickness had highest determination (0.813) for last menstrual period followed by trans-cerebellar diameter (0.802). Combining trans-cerebellar diameter and placental thickness increased determination (0.902) for last menstrual period. Conclusion: Combined use of trans-cerebellar diameter and placental thickness in the third trimester of pregnancy is a reliable indicator for gestational age in women whose last menstrual period is unreliable or unknown, but placental thickness had higher accuracy than trans-cerebellar diameter.展开更多
Necrotic feet secondary to vascular compromise in the diabetic patient may require an emergent guillotine amputation. Unrecognized, retained hardware in a distal ankle years after fracture repair may complicate the in...Necrotic feet secondary to vascular compromise in the diabetic patient may require an emergent guillotine amputation. Unrecognized, retained hardware in a distal ankle years after fracture repair may complicate the intraoperative guillotine amputation at the transtibial/fibula level. Troubleshooting such an unexpected surgical problem is not necessarily straightforward depending on the clinical situation. Presented is a case report where a patient with a necrotic burned foot failed to inform the burn team that he had implanted ankle hardware, prior to his surgical intervention. A successful amputation was completed after proceeding down a specific algorithm devised for such a scenario.展开更多
Tourism literature is a window for foreigners to know China and a medium for publicizing Chinese culture.Increasing the quality of translation of tourism literature is of great significance in promoting Chinese touris...Tourism literature is a window for foreigners to know China and a medium for publicizing Chinese culture.Increasing the quality of translation of tourism literature is of great significance in promoting Chinese tourisms' further development.This paper explores the strategies to deal with the translation of tourism literature,taking Skopos Theory as the theoretical base.展开更多
To establish a cytologic expressing system of rat glutathione S-transferase pi (GST-pi) cDNA for detecting the resistance of HeLa cells to anticancer drugs. Methods The assessment was made with various anticancer dr...To establish a cytologic expressing system of rat glutathione S-transferase pi (GST-pi) cDNA for detecting the resistance of HeLa cells to anticancer drugs. Methods The assessment was made with various anticancer drugs (adriamycin, mitomycin, cisplatinum and vincristine) that showed different cytotoxicities in transfectant HeLa cells with pSV-GT containing rat GST-pi cDNA (HeLa/pSV-GT) or control pSV-neo (HeLa/pSV-neo). Expression levels of GST-pi mRNA in HeLa/pSV-GT and HeLa/pSV-neo were measured by in situ hybridization using Digoxin-labelled cDNA probe. Results HeLa/pSV-GT expressed significantly high degree of GST-pi mRNA, whereas both HeLa/pSV-neo and HeLa cells had very low expression. Cytotoxicities of HeLa/pSV-GT and HeLa/pSV-neo with 4 anticancer drugs were measured by MTT assay. Drug concentrations for yielding 50% inhibition (IC50) in HeLa/pSV-GT by adriamycin, mitomycin and cisplatinum were 70.13 靏/mL, 10.95 靏/mL and 16.52 靏/mL, respectively. In contrast, IC50 in HeLa/pSV-neo was 10.34 靏/mL, 7.48 靏/mL and 13.70 靏/mL, respectively. The cytotoxicities of vincristine on both HeLa/pSV-GT and HeLa/pSV-neo were not significantly different. Conclusions Our findings suggest that HeLa/pSV-GT containing rat GST-pi cDNA is resistant to some anticancer drugs due to overexpression of GST-pi. Also, HeLa/pSV-GT cell line could serve as a useful cytogenetic model for further research.展开更多
Challenges in translation can be approached from the perspective of intercultural communication, and translation also plays a major role in communication between cultures. The translators of news should be culture con...Challenges in translation can be approached from the perspective of intercultural communication, and translation also plays a major role in communication between cultures. The translators of news should be culture conscious and adopt flexible strategies in dealing with cultural differences. In news translation, the readability of the target language text counts the most.展开更多
文摘AIM:To compare intraocular pressure(IOP)measured via the trans palpebral IOP(tp IOP)method using a Diaton or with a Goldman applanation tonometer(GAT)and study the determinants of IOP difference in eyes undergoing transepithelial photorefractive keratectomy(TPRK)for myopia.METHODS:This cross-sectional validation study was held in 2020 in an eye hospital in Saudi Arabia.IOP was measured by Diaton and GAT before treatment,after one week,and one month of TPRK.It is considered if IOP difference by Diaton and GAT was less than±2 mm Hg acceptable.The IOP difference was tested if correlated to spherical equivalent(SE),central corneal thickness(CCT),age,gender,or tp IOP.RESULTS:Totolly 200 myopic eyes of 100 patients were included in the study.The mean difference of IOP measured by two methods before TPRK,1wk,and 1mo after TPRK were 0.790,-0.790,and-0.920 mm Hg,respectively(P<0.001).Diaton could measure IOP effectively 89.5%eyes before TPRK and 82%and 84%at 1wk and 1mo after TPTK,respectively.At week 1,IOP differences were significantly correlated to baseline CCT(P=0.02)and tp IOP at week 1(P<0.001).One month after TPRK,only tp IOP was significantly correlated to the difference in IOP(P<0.001).CONCLUSION:Diaton is a good screening tool for IOP before TPRK.It helps in monitoring IOP after surgery.Although more practical,it is less efficient than GAT.In eyes with high myopia and low tp IOP before surgery,IOP post-TPRK by Diaton and GAT could differ.
文摘目的:探究动态对比增强磁共振成像(dynamic contrast-enhanced magnetic resonance imaging,DCE-MRI)技术定量容积运转常数(Ktrans)、速率常数(K_(ep))指导肝脏肿块定性诊断的价值。方法:选取2018年1月—2022年12月期间苏州市相城区中医医院收治的肝脏不明肿块患者共计92例,全部研究对象均接受DCE-MRI定量的Ktrans、K_(ep)检测,以组织病理学活检结果作为金标准,评估DCE-MRI定量的K^(trans)、K_(ep)检测应用于肝脏肿块定性诊断的价值。结果:在92例研究对象中,最终确诊为恶性病变者28例;非恶性病变者64例。两组研究对象的DCE-MRI检测结果显示,恶性病变组患者的Ktrans、K_(ep)水平均高于非恶性病变组,差异存在统计学意义(P<0.05);ROC曲线显示,DCE-MRI定量K^(trans)、K_(ep)应用于肝脏肿块定性检查的曲线下面积(AUC)分别为0.878、0.922,两项指标联合诊断的AUC为0.972。由此可见,K^(trans)、K_(ep)应用于肝脏肿块定性均具有较高的评估价值(P<0.05),且联合检测的评估效果优于单项检测。结论:DCE-MRI定量K^(trans)、K_(ep)应用于肝脏肿块定性均具有较高的评估价值,且联合检测的评估效果优于单项检测,值得借鉴应用。
基金Project supported by the National Natural Science Foundation of China (Grant Nos.41805014 and 62205005)the Key Program of the Natural Science Research Fund of the Education Department of Anhui Province (Grant Nos.KJ2021A0637 and KJ2021A0638)the Key Program in the Youth Talent Support Plan in Universities of Anhui Province (Grant No.gxyqZD2020032)。
文摘Accurate spectroscopic data for H_(2)^(16)O in the 1.1μm region are particularly important for the study of Earth's atmosphere.The pure water vapor molecular spectra were measured based on direct laser absorption spectroscopy using a narrow line-width external cavity diode laser combined with a high-precision Fabry-Pérot etalon.A total of 31 H_(2)^(16)O transitions were studied for the first time by using the speed-dependent Nelkin-Ghatak profile and the Hartmann-Tran profile.From an accurate line-shape analysis,we obtained the line intensities and the self-broadening coefficients,and they are compared with the available data reported in the HITRAN 2016 database and the HITRAN 2020 database.Finally,we obtained information on the influence of Dicke narrowing,as well as the correlations between Dicke narrowing and speed dependence,and of speed-dependent effects.
文摘Background: Accurate determination of gestational age has become important for deciding the appropriate time for termination of the pregnancy as well as to monitor the fetal growth during the entire period of pregnancy. Objective: The aim of the study was to assess whether the trans-cerebellar diameter, placental thickness or combining both of them is more accurate for assessment of gestational age in the 3<sup>rd</sup> trimester of pregnancy. Patients and Methods: This is a cross sectional study conducted at outpatient Clinic and Obstetric ward, Ain Shams University Maternity Hospital, over a period of six months from March 2019 to September 2019. One hundred pregnant women were recruited according to inclusion criteria either from outpatient clinic or were admitted in obstetric ward Ain Shams Maternity Hospital to find out the most accurate fetal biometric measurement in the third trimester either trans-cerebellar diameter placental thickness or both compared to reliable LMP (last menstrual period) dates confirmed by crown rump length (CRL) in the first trimester. Results: Trans-cerebellar diameter mean ± SD was 46.0 ± 3.5 with range 38.2 - 51.7. The mean of placental thickness was 39.6 ± 7.1 with range 22.8 - 54.3. Placental thickness had highest determination (0.813) for last menstrual period followed by trans-cerebellar diameter (0.802). Combining trans-cerebellar diameter and placental thickness increased determination (0.902) for last menstrual period. Conclusion: Combined use of trans-cerebellar diameter and placental thickness in the third trimester of pregnancy is a reliable indicator for gestational age in women whose last menstrual period is unreliable or unknown, but placental thickness had higher accuracy than trans-cerebellar diameter.
文摘Necrotic feet secondary to vascular compromise in the diabetic patient may require an emergent guillotine amputation. Unrecognized, retained hardware in a distal ankle years after fracture repair may complicate the intraoperative guillotine amputation at the transtibial/fibula level. Troubleshooting such an unexpected surgical problem is not necessarily straightforward depending on the clinical situation. Presented is a case report where a patient with a necrotic burned foot failed to inform the burn team that he had implanted ankle hardware, prior to his surgical intervention. A successful amputation was completed after proceeding down a specific algorithm devised for such a scenario.
文摘Tourism literature is a window for foreigners to know China and a medium for publicizing Chinese culture.Increasing the quality of translation of tourism literature is of great significance in promoting Chinese tourisms' further development.This paper explores the strategies to deal with the translation of tourism literature,taking Skopos Theory as the theoretical base.
基金the National Natural Science Foundation of China.
文摘To establish a cytologic expressing system of rat glutathione S-transferase pi (GST-pi) cDNA for detecting the resistance of HeLa cells to anticancer drugs. Methods The assessment was made with various anticancer drugs (adriamycin, mitomycin, cisplatinum and vincristine) that showed different cytotoxicities in transfectant HeLa cells with pSV-GT containing rat GST-pi cDNA (HeLa/pSV-GT) or control pSV-neo (HeLa/pSV-neo). Expression levels of GST-pi mRNA in HeLa/pSV-GT and HeLa/pSV-neo were measured by in situ hybridization using Digoxin-labelled cDNA probe. Results HeLa/pSV-GT expressed significantly high degree of GST-pi mRNA, whereas both HeLa/pSV-neo and HeLa cells had very low expression. Cytotoxicities of HeLa/pSV-GT and HeLa/pSV-neo with 4 anticancer drugs were measured by MTT assay. Drug concentrations for yielding 50% inhibition (IC50) in HeLa/pSV-GT by adriamycin, mitomycin and cisplatinum were 70.13 靏/mL, 10.95 靏/mL and 16.52 靏/mL, respectively. In contrast, IC50 in HeLa/pSV-neo was 10.34 靏/mL, 7.48 靏/mL and 13.70 靏/mL, respectively. The cytotoxicities of vincristine on both HeLa/pSV-GT and HeLa/pSV-neo were not significantly different. Conclusions Our findings suggest that HeLa/pSV-GT containing rat GST-pi cDNA is resistant to some anticancer drugs due to overexpression of GST-pi. Also, HeLa/pSV-GT cell line could serve as a useful cytogenetic model for further research.
文摘Challenges in translation can be approached from the perspective of intercultural communication, and translation also plays a major role in communication between cultures. The translators of news should be culture conscious and adopt flexible strategies in dealing with cultural differences. In news translation, the readability of the target language text counts the most.
