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Innovative immunosuppression in kidney transplantation:A challenge for unmet needs
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作者 Maurizio Salvadori Aris Tsalouchos 《World Journal of Transplantation》 2022年第3期27-41,共15页
Due to the optimal results obtained in kidney transplantation and to the lack of interest of the industries,new innovative drugs in kidney transplantation are difficult to be encountered.The best strategy to find the ... Due to the optimal results obtained in kidney transplantation and to the lack of interest of the industries,new innovative drugs in kidney transplantation are difficult to be encountered.The best strategy to find the new drugs recently developed or under development is to search in the sections of kidney transplantation still not completely covered by the drugs on the market.These unmet needs are the prevention of delayed graft function(DGF),the protection of the graft over the long time and the desensitization of preformed anti human leukocyte antigen antibodies and the treatment of the acute antibody-mediated rejection.These needs are particularly relevant due to the expansion of some kind of kidney transplantation as transplantation from non-heart beating donor and in the case of antibody-incompatible grafts.The first are particularly exposed to DGF,the latter need a safe desensitization and a safe treatments of the antibody mediated rejections that often occur.Particular caution is needed in treating these drugs.First,they are described in very recent studies and the follow-up of their effect is of course rather short.Second,some of these drugs are still in an early phase of study,even if in well-conducted randomized controlled trials.Particular caution and a careful check need to be used in trials launched 2 or 3 years ago.Indeed,is always necessary to verify whether the study is still going on or whether and why the study itself was abandoned. 展开更多
关键词 New drugs unmet needs in kidney transplantation Delayed graft function Long-term outcomes Kidney inflammation Anti-human leukocyte antigen antibodies
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Supportive care needs of women with gynecologic cancer and factors affecting in Turkiye: a cross sectional study
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作者 Ebru Var Evşen Nazik 《Nursing Communications》 2024年第7期1-7,共7页
Background:Identifying and managing patients'supportive care needs is an essential component of health care.The cancer patients'needs are multidimensional and it is important to identify these needs.This study... Background:Identifying and managing patients'supportive care needs is an essential component of health care.The cancer patients'needs are multidimensional and it is important to identify these needs.This study was conducted to assess supportive care needs of women with gynecologic cancer and affecting factors.Methods:This cross-sectional study consisted of 98 women with gynecologic cancer.The data of the study was gathered using“Personal Information Form”and the“James Supportive Care Screening”.Results:The most frequently reported unmet needs of gynecologic cancer patients were emotional issues,including uncertainty(87.6%),fears(85.7%),feeling down(86.7%),worry(87.6%),loss of interest in usual activities(73.3%)and physical symptoms including fatigue/lack of energy(81.9%),weakness(81.9%),lack of appetite(76.2%).The most frequently reported social/practical problems was transportation problems(50%).The mean scores for JSCS was 29.72±15.57.There were a statistically significant difference was found only between family type,stage of the disease,and time of diagnosis,and the total mean scores of the JSCS(p<0.05).Conclusion:It has been determined that patients with gynecological cancer mostly experience emotional and physical problems.Health professionals working in the oncology unit should be aware of unmet needs.Certain programs and services to address the identified unmet needs should be provided. 展开更多
关键词 gynecologic cancer unmet needs supportive care NURSING
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Unmet needs as indicator of improving chronic care delivery system in China 被引量:2
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作者 Xia-Tong Ke Chun-Lu Wang +1 位作者 Jack Warren Salmon Wen-Xi Tang 《Chronic Diseases and Translational Medicine》 CSCD 2021年第1期1-13,共13页
In 2009, China strengthened its public health service system. Since then, the country has made remarkable achievements in community-based chronic disease prevention and control;however, certain groups still have unmet... In 2009, China strengthened its public health service system. Since then, the country has made remarkable achievements in community-based chronic disease prevention and control;however, certain groups still have unmet needs. During 2019 to 2029, China will consolidate the top-level design of its medical health system. During this period, the coordination of department policies, improvement of service delivery mechanisms, building an integrated health service system, and other issues will be highlighted. This study will provide a basis for designing China’s chronic disease prevention and control system during the next stage of development. We will consider the unmet needs of patients with chronic diseases as an indicator for remodeling the prediction system in combination with the elements and structural theories of complex health systems. In this article, we first introduce the definition and measurement methods of unmet needs. Second, we identify the existing unmet needs found among patients with chronic diseases with reference to the chronic disease prevention and control policies of China as well as current service items. Finally, we propose the design of community chronic disease service package for the next development stage based on unmet needs of patients with chronic diseases. We also provide suggestions for how to improve China’s chronic care delivery system. 展开更多
关键词 unmet needs Chronic care Integrated delivery system Policy review
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Healthcare needs and access in a sample of Chinese young adults in Vancouver, British Columbia: A qualitative analysis
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作者 Christine H.K.Ou Sabrina T.Wong +1 位作者 Jean-Fréderic Levesque Elizabeth Saewyc 《International Journal of Nursing Sciences》 2017年第2期173-178,共6页
Objectives: Immigrants of Chinese ethnicity and young people (between 18 and 30 years of age) are known to access health services less frequently and may be at greater risk for experiencing unmet health needs. The pur... Objectives: Immigrants of Chinese ethnicity and young people (between 18 and 30 years of age) are known to access health services less frequently and may be at greater risk for experiencing unmet health needs. The purpose of this study was to examine the health beliefs, health behaviors, primary care access, and perceived unmet healthcare needs of Chinese young adults.Methods: Semi-structured in-depth interviews were carried out with eight Chinese young adults in Vancouver, Canada. Results: A content analysis revealed that these Chinese young adults experienced unmet healthcare needs, did not have a primary care provider, and did not access preventive services. Cultural factors such as strong family ties, filial piety, and the practice of Traditional Chinese Medicine influenced their health behaviors and healthcare access patterns. Conclusion: Chinese young adults share similar issues with other young adults in relation to not having a primary care provider and accessing preventive care but their health beliefs and practices make their needs for care unique from other young adults. 展开更多
关键词 Chinese young adults IMMIGRANTS Primary healthcare unmet health needs Health behaviours ACCULTURATION
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Unmet supportive care needs in families of children with chronic health conditions: an Australian cross‑sectional study
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作者 Sangeetha Thomas Linda K.Byrne +2 位作者 Nicholas P.Ryan Christel Hendrieckx Victoria White 《World Journal of Pediatrics》 SCIE CSCD 2023年第12期1181-1191,共11页
Background The aim of this study was to identify similarities and diferences in the unmet supportive care needs(USCN)of families of children with major chronic health conditions(CHCs)using a universal need assessment ... Background The aim of this study was to identify similarities and diferences in the unmet supportive care needs(USCN)of families of children with major chronic health conditions(CHCs)using a universal need assessment tool.Methods A cross-sectional online survey involving parents of children with congenital heart disease(CHD),type 1 diabetes mellitus(T1D),cancer,and asthma diagnosed within the last 5 years recruited via social media and support organizations.Thirty-four items assessing the USCN across six domains(care needs,physical and social needs,informational needs,support needs,fnancial needs,child-related emotional needs)were responded to on a 4-point Likert scale[no need(1)to high need(4)].Descriptive statistics identifed the level of need,and linear regressions identifed factors associated with higher need domain scores.Due to small numbers,the asthma group was excluded from comparisons across CHCs.Results One hundred and ninety-four parents completed the survey(CHD:n=97,T1D:n=50,cancer:n=39,and asthma:n=8).Parents of children with cancer were most likely to report at least one USCN(92%),followed by parents of children with T1D(62%).The fve most commonly reported USCN across CHCs were drawn from four domains:child-related emotional,support,care,and fnancial.Three need items were included in the top fve needs for all conditions.A higher USCN was associated with a greater frequency of hospital visits and the absence of parental support.Conclusions Using a universal need assessment tool,this is one of the frst studies to characterize USCN in families of children diagnosed with common CHCs.While proportions endorsing diferent needs varied across conditions,the most endorsed needs were similar across the illness groups.This suggests that support programs or services could be shared across diferent CHCs. 展开更多
关键词 CHILDREN Chronic illness Need assessment unmet supportive care needs
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Family planning program under low fertility:where to go
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作者 Baochang Gu 《China Population and Development Studies》 2021年第3期61-68,共8页
This commentary is intended to take China as a case to discuss the mission of the family planning program under low fertility scenario.After a brief review of the initiation of family planning program in the 1970s,as ... This commentary is intended to take China as a case to discuss the mission of the family planning program under low fertility scenario.After a brief review of the initiation of family planning program in the 1970s,as well as the reorientation of family planning program since ICPD in 1994,it will focus on the new mission for the family planning program under low fertility scenario in the twenty-first century,in particular concerning the issue of induced abortion among the others.Given the enormous evidence of unmet needs in reproductive health as identified in the discussion,it is argued that family planning programmes are in fact even more needed than ever before under low-fertility scenario,and should not be abandoned but strengthened,which clearly has nothing to do to call back to the program for population control in the 1970s-1980s,and nor even go back to the program for“two reorientations”in the 1990s,but to aim to serving the people to fulfill their reproductive health and reproductive rights in light of ICPD and SDGs,and to become truly integral component of“Healthy China 2030”Strategy. 展开更多
关键词 Family planning program Low fertility China ABORTION unmet needs
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