Environmental and ecological problems in the urban-rural integration were analyzed, characteristics of urban green space system introduced, such as excellent landscape eco-structure, distinctive historical and humanis...Environmental and ecological problems in the urban-rural integration were analyzed, characteristics of urban green space system introduced, such as excellent landscape eco-structure, distinctive historical and humanistic features, and diversified natural landscape resources, and also challenges pointed out. Evolution, overall spatial structure and conservation concept of conservation-minded urban green space system planning were elaborated, on the basis of which the evaluation system of conservation-minded urban green space system was studied, and it was proposed that mutual relationship between impact factors of compound value and qualitative evaluation factors should be taken into consideration as a whole in evaluating conservation effects of green space system. Quantitative evaluation indexes and qualitative evaluation measures were analyzed, an objective and precise evaluation system for the conservation-minded urban green space system was established by combining qualitative and quantitative analysis to improve ecological environment during the urbanization, and fully show planning concepts of conservation-minded green space system.展开更多
This study proposes a novel approach to optimizing individual work schedules for book digitization using mixed-integer programming (MIP). By leveraging the power of MIP solvers, we aimed to minimize the overall digiti...This study proposes a novel approach to optimizing individual work schedules for book digitization using mixed-integer programming (MIP). By leveraging the power of MIP solvers, we aimed to minimize the overall digitization time while considering various constraints and process dependencies. The book digitization process involves three key steps: cutting, scanning, and binding. Each step has specific requirements and limitations such as the number of pages that can be processed simultaneously and potential bottlenecks. To address these complexities, we formulate the problem as a one-machine job shop scheduling problem with additional constraints to capture the unique characteristics of book digitization. We conducted a series of experiments to evaluate the performance of our proposed approach. By comparing the optimized schedules with the baseline approach, we demonstrated significant reductions in the overall processing time. In addition, we analyzed the impact of different weighting schemes on the optimization results, highlighting the importance of identifying and prioritizing critical processes. Our findings suggest that MIP-based optimization can be a valuable tool for improving the efficiency of individual work schedules, even in seemingly simple tasks, such as book digitization. By carefully considering specific constraints and objectives, we can save time and leverage resources by carefully considering specific constraints and objectives.展开更多
The construction projects’ dynamic and interconnected nature requires a comprehensive understanding of complexity during pre-construction. Traditional tools such as Gantt charts, CPM, and PERT often overlook uncertai...The construction projects’ dynamic and interconnected nature requires a comprehensive understanding of complexity during pre-construction. Traditional tools such as Gantt charts, CPM, and PERT often overlook uncertainties. This study identifies 20 complexity factors through expert interviews and literature, categorising them into six groups. The Analytical Hierarchy Process evaluated the significance of different factors, establishing their corresponding weights to enhance adaptive project scheduling. A system dynamics (SD) model is developed and tested to evaluate the dynamic behaviour of identified complexity factors. The model simulates the impact of complexity on total project duration (TPD), revealing significant deviations from initial deterministic estimates. Data collection and analysis for reliability tests, including normality and Cronbach alpha, to validate the model’s components and expert feedback. Sensitivity analysis confirmed a positive relationship between complexity and project duration, with higher complexity levels resulting in increased TPD. This relationship highlights the inadequacy of static planning approaches and underscores the importance of addressing complexity dynamically. The study provides a framework for enhancing planning systems through system dynamics and recommends expanding the model to ensure broader applicability in diverse construction projects.展开更多
Rational laboratory layout design and scientific management systems are key to improving overall laboratory efficiency and safety,providing a solid foundation and guarantee for the smooth progress of scientific resear...Rational laboratory layout design and scientific management systems are key to improving overall laboratory efficiency and safety,providing a solid foundation and guarantee for the smooth progress of scientific research.This article addresses a series of issues such as low testing efficiency caused by unreasonable laboratory layouts,incomplete or outdated equipment configurations affecting testing accuracy,and safety hazards arising from the lack of effective laboratory management systems.It conducts an in-depth exploration of the design and planning strategies for physicochemical laboratories.By proposing specific designs and guidelines for the location selection,functional zoning,and layout requirements of physicochemical laboratories,the aim is to optimize laboratory space utilization,enhance testing efficiency,and ensure the advancement of equipment configurations and the accuracy of testing precision.Simultaneously,it emphasizes the establishment of an effective laboratory management system to prevent and control safety hazards,safeguarding the lives of laboratory personnel and ensuring stable laboratory operations.展开更多
Objective:To understand the current situation of career planning awareness and readiness of freshman medical students with a background in digital medicine,and to provide references for optimizing the medical educatio...Objective:To understand the current situation of career planning awareness and readiness of freshman medical students with a background in digital medicine,and to provide references for optimizing the medical education system and career guidance.Methods:A cross-sectional study was conducted on freshman medical students at a university in Yunnan Province using questionnaire survey.Results:A total of 272 questionnaires were distributed and 264 valid questionnaires were returned,yielding an effective response rate of 97.10%.The average score of digital medical awareness of freshman medical students was(70.50±8.81),and 63.63%of the students had a high awareness(score≧70);The average score of career planning awareness and readiness of freshman medical students was(91.76±14.87),and 60.63%of students had high awareness and readiness(score≧90).Pearson correlation analysis showed that the total score of digital medical awareness was positively correlated with the total score of career planning awareness and readiness(r=0.13,P<0.05).Conclusion:Freshman medical students’career planning awareness and readiness are generally good,but their practical application of digital medical-related skills still needs improvement.It is suggested that schools strengthen the integration of interdisciplinary curriculum,introduce digital vocational training modules,and formulate differentiated guidance strategies for different majors to enhance students’professional competitiveness in the digital medical era.展开更多
Village revitalization is a major development strategy in China,where village planning plays as its critical component.Taking village planning of De’an County in Jiangxi Province as an example,this paper explored the...Village revitalization is a major development strategy in China,where village planning plays as its critical component.Taking village planning of De’an County in Jiangxi Province as an example,this paper explored the significant importance of village planning in promoting rural revitalization along with its corresponding promote mechanisms.Through in-depth research on the detailed situation of village planning and implementation in Jiangxi,this paper summarized that some challenges exist,including backward planning,poor planning consciousness,difficulties in planning implementation.Based on these findings,the paper analyzed the challenges of village land resource scarcity,village images lacking in uniqueness features,and insufficient rural infrastructure construction.Furthermore,it proposed strategies such as taking the lead in planning from the beginning,advancing practical implementation at a high level,adhering to bottom-line thinking,and coordinating high-quality rural land protection and development,applying strategies such as ecological and pleasant living,building villages suitable for living and working,and construction of beautiful countryside,aiming to provide valuable reference for related research fields.展开更多
Objective:This study aimed to explore the readiness for advance care planning(ACP)among older adults in Macao’s day service centers and investigate the influencing factors.Methods:A cross-sectional study was conducte...Objective:This study aimed to explore the readiness for advance care planning(ACP)among older adults in Macao’s day service centers and investigate the influencing factors.Methods:A cross-sectional study was conducted from October to December 2022 using a convenience sampling method.A total of 312 older adults were selected from 13 day service centers for older adults in Macao,China.The Advance Care Planning Acceptance Questionnaire and the Family Adaptation,Partnership,Growth,Affection,Resolve(APGAR)Scale were used to survey the older adults.Results:A total of 306 older adults completed the survey.The score for advance care planning readiness was 65.55±10.69,and 59.5%of participants(n=182)were willing to participate in ACP.The family function score was 7.24±2.51,while 70.3%of participants were from a highly functional family.The higher family function indicating a higher readiness for advance care planning(r=0.396,P<0.001).The multiple linear regression analysis indicated that the variables“age,”“knowledge of ACP,”“experience with ACP,”and“received resuscitation of yourself,relatives or friends”combined with“family function”can influence advance care planning readiness among older adults(R^(2)=0.317,F=27.898,P<0.001).Conclusions:Older adults in Macao’s day service centers were willing to engage in ACP.The importance of family involvement is highlighted in the ACP readiness.Health education and improved family communication are vital for promoting ACP,which ensures individuals receive care when they lack the capacity to make that choice.Additionally,healthcare professionals should enhance communication and education with older adults during the medical care process.展开更多
Legged robots have always been a focal point of research for scholars domestically and internationally.Compared to other types of robots,quadruped robots exhibit superior balance and stability,enabling them to adapt e...Legged robots have always been a focal point of research for scholars domestically and internationally.Compared to other types of robots,quadruped robots exhibit superior balance and stability,enabling them to adapt effectively to diverse environments and traverse rugged terrains.This makes them well-suited for applications such as search and rescue,exploration,and transportation,with strong environmental adaptability,high flexibility,and broad application prospects.This paper discusses the current state of research on quadruped robots in terms of development status,gait trajectory planning methods,motion control strategies,reinforcement learning applications,and control algorithm integration.It highlights advancements in modeling,optimization,control,and data-driven approaches.The study identifies the adoption of efficient gait planning algorithms,the integration of reinforcement learning-based control technologies,and data-driven methods as key directions for the development of quadruped robots.The aim is to provide theoretical references for researchers in the field of quadruped robotics.展开更多
Machine learning-assisted retrosynthesis planning aims to utilize machine learning(ML)algorithms to find synthetic pathways for target compounds.In recent years,with the development of artificial intelligence(AI),espe...Machine learning-assisted retrosynthesis planning aims to utilize machine learning(ML)algorithms to find synthetic pathways for target compounds.In recent years,with the development of artificial intelligence(AI),especially ML,researchers’interest in ML-assisted retrosynthesis planning has rapidly increased,bringing development and opportunities to the field.In this review,we aim to provide a comprehensive understanding of ML-assisted retrosynthesis planning.We first discuss the formal definition and the objective of retrosynthesis planning,and organize a modular framework which includes four modules:data preparation,data preprocessing,pathway generation and evaluation,and pathway verification.Then,we sequentially review the current status of the first three modules(except pathway verification)in the ML-assisted retrosynthesis planning framework,including ideas,methods,and latest progress.Following that,we specifically discuss large language models in retrosynthesis planning.Finally,we summarize the extant challenges that are faced by current ML-assisted retrosynthesis planning research and offer a perspective on future research directions and development.展开更多
Despite its immense potential,the application of digital twin technology in real industrial scenarios still faces numerous challenges.This study focuses on industrial assembly lines in sectors such as microelectronics...Despite its immense potential,the application of digital twin technology in real industrial scenarios still faces numerous challenges.This study focuses on industrial assembly lines in sectors such as microelectronics,pharmaceuticals,and food packaging,where precision and speed are paramount,applying digital twin technology to the robotic assembly process.The innovation of this research lies in the development of a digital twin architecture and system for Delta robots that is suitable for real industrial environments.Based on this system,a deep reinforcement learning algorithm for obstacle avoidance path planning in Delta robots has been developed,significantly enhancing learning efficiency through an improved intermediate reward mechanism.Experiments on communication and interaction between the digital twin system and the physical robot validate the effectiveness of this method.The system not only enhances the integration of digital twin technology,deep reinforcement learning and robotics,offering an efficient solution for path planning and target grasping inDelta robots,but also underscores the transformative potential of digital twin technology in intelligent manufacturing,with extensive applicability across diverse industrial domains.展开更多
The global demand for effective skin injury treatments has prompted the exploration of tissue engineering solutions.While three-dimensional(3D)bioprinting has shown promise,challenges persist with respect to achieving...The global demand for effective skin injury treatments has prompted the exploration of tissue engineering solutions.While three-dimensional(3D)bioprinting has shown promise,challenges persist with respect to achieving timely and compatible solutions to treat diverse skin injuries.In situ bioprinting has emerged as a key new technology,since it reduces risks during the implantation of printed scaffolds and demonstrates superior therapeutic effects.However,maintaining printing fidelity during in situ bioprinting remains a critical challenge,particularly with respect to model layering and path planning.This study proposes a novel optimization-based conformal path planning strategy for in situ bioprinting-based repair of complex skin injuries.This strategy employs constrained optimization to identify optimal waypoints on a point cloud-approximated curved surface,thereby ensuring a high degree of similarity between predesigned planar and surface-mapped 3D paths.Furthermore,this method is applicable for skin wound treatments,since it generates 3D-equidistant zigzag curves along surface tangents and enables multi-layer conformal path planning to facilitate the treatment of volumetric injuries.Furthermore,the proposed algorithm was found to be a feasible and effective treatment in a murine back injury model as well as in other complex models,thereby showcasing its potential to guide in situ bioprinting,enhance bioprinting fidelity,and facilitate improvement of clinical outcomes.展开更多
BACKGROUND Kidney transplantation is one of the most effective treatments for patients with end-stage renal disease.However,many regions face low deceased donor rates and limited ABO-compatible transplant availability...BACKGROUND Kidney transplantation is one of the most effective treatments for patients with end-stage renal disease.However,many regions face low deceased donor rates and limited ABO-compatible transplant availability,which increases reliance on living donors.These regional challenges necessitate the implementation of kidney paired donation(KPD)programs to overcome incompatibilities such as ABO mismatch or positive cross-matching,even when suitable and willing donors are available.AIM To evaluate the effectiveness of a single-center domino KPD model in both operational planning and clinical management processes and to assess its impact on clinical outcomes.METHODS Between April 2020 and January 2024,we retrospectively evaluated patients enrolled in our center’s domino kidney transplantation program.Donor-recipient pairs unable to proceed due to ABO incompatibility or positive cross-matching with their own living donors were included.Donors and recipients were assessed based on blood group compatibility,HLA tissue typing,and negative cross-match results.A specialized computer algorithm grouped patients into three-way,fourway,and five-way chains.All surgical procedures were performed on the same day at a single center.RESULTS A total of 169 kidney transplants were performed,forming 52 domino chains.These domino KPD transplants accounted for a notable proportion of our center’s overall transplant activity,which included both living donor kidney transplants and deceased donor transplants.Among these chains,the primary reasons for participation were ABO incompatibility(74%),positive cross-matching(10%),and the desire to improve HLA mismatch(16%).Improved HLA mismatch profiles and high graft survival(96%at 1 year,92%at 3 years)and patient survival(98%at 1 year,94%at 3 years)rates were observed,as well as low acute rejection episodes.CONCLUSION The single-center domino KPD model enhanced transplant opportunities for incompatible donor-recipient pairs while maintaining excellent clinical outcomes.By providing a framework that addresses regional challenges,improves operational efficiency,and optimizes clinical management,this model offers actionable insights to reduce waiting lists and improve patient outcomes.展开更多
An improved version of the sparse A^(*)algorithm is proposed to address the common issue of excessive expansion of nodes and failure to consider current ship status and parameters in traditional path planning algorith...An improved version of the sparse A^(*)algorithm is proposed to address the common issue of excessive expansion of nodes and failure to consider current ship status and parameters in traditional path planning algorithms.This algorithm considers factors such as initial position and orientation of the ship,safety range,and ship draft to determine the optimal obstacle-avoiding route from the current to the destination point for ship planning.A coordinate transformation algorithm is also applied to convert commonly used latitude and longitude coordinates of ship travel paths to easily utilized and analyzed Cartesian coordinates.The algorithm incorporates a hierarchical chart processing algorithm to handle multilayered chart data.Furthermore,the algorithm considers the impact of ship length on grid size and density when implementing chart gridification,adjusting the grid size and density accordingly based on ship length.Simulation results show that compared to traditional path planning algorithms,the sparse A^(*)algorithm reduces the average number of path points by 25%,decreases the average maximum storage node number by 17%,and raises the average path turning angle by approximately 10°,effectively improving the safety of ship planning paths.展开更多
As the development of new power systems accelerates and the impacts of high renewable energy integration and extreme weather intensify,grid-alternative energy storage is garnering increasing attention for its grid-int...As the development of new power systems accelerates and the impacts of high renewable energy integration and extreme weather intensify,grid-alternative energy storage is garnering increasing attention for its grid-interaction benefits and clear business models.Consequently,assessing the value of grid-alternative energy storage in the systemtransition has become critically important.Considering the performance characteristics of storage,we propose a value assessment frame-work for grid-alternative energy storage,quantifying its non-wires-alternative effects from both cost and benefit perspectives.Building on this,we developed a collaborative planning model for energy storage and transmission grids,aimed at maximizing the economic benefits of storage systems while balancing investment and operational costs.The model considers regional grid interconnections and their interactions with system operation.By participating in system operations,grid-alternative energy storage not only maximizes its own economic benefits but also generates social welfare transfer effects.Furthermore,based on multi-regional interconnected planning,grid-alternative energy storage can reduce system costs by approximately 35%,with the most significant changes observed in generation costs.Multi-regional coordinated planning significantly enhances the sys-tem’s flexibility in regulation.However,when the load factor of interconnection lines between regions remains constant,system operational flexibility tends to decrease,leading to a roughly 28.9%increase in storage investment.Additionally,under regional coordinated planning,the greater the disparity in wind power integration across interconnected regions,the more noticeable the reduction in system costs.展开更多
To improve the efficiency and accuracy of path planning for fan inspection tasks in thermal power plants,this paper proposes an intelligent inspection robot path planning scheme based on an improved A^(*)algorithm.The...To improve the efficiency and accuracy of path planning for fan inspection tasks in thermal power plants,this paper proposes an intelligent inspection robot path planning scheme based on an improved A^(*)algorithm.The inspection robot utilizes multiple sensors to monitor key parameters of the fans,such as vibration,noise,and bearing temperature,and upload the data to the monitoring center.The robot’s inspection path employs the improved A^(*)algorithm,incorporating obstacle penalty terms,path reconstruction,and smoothing optimization techniques,thereby achieving optimal path planning for the inspection robot in complex environments.Simulation results demonstrate that the improved A^(*)algorithm significantly outperforms the traditional A^(*)algorithm in terms of total path distance,smoothness,and detour rate,effectively improving the execution efficiency of inspection tasks.展开更多
Rational distribution network planning optimizes power flow distribution,reduces grid stress,enhances voltage quality,promotes renewable energy utilization,and reduces costs.This study establishes a distribution netwo...Rational distribution network planning optimizes power flow distribution,reduces grid stress,enhances voltage quality,promotes renewable energy utilization,and reduces costs.This study establishes a distribution network planning model incorporating distributed wind turbines(DWT),distributed photovoltaics(DPV),and energy storage systems(ESS).K-means++is employed to partition the distribution network based on electrical distance.Considering the spatiotemporal correlation of distributed generation(DG)outputs in the same region,a joint output model of DWT and DPV is developed using the Frank-Copula.Due to the model’s high dimensionality,multiple constraints,and mixed-integer characteristics,bilevel programming theory is utilized to structure the model.The model is solved using a mixed-integer particle swarmoptimization algorithm(MIPSO)to determine the optimal location and capacity of DG and ESS integrated into the distribution network to achieve the best economic benefits and operation quality.The proposed bilevel planning method for distribution networks is validated through simulations on the modified IEEE 33-bus system.The results demonstrate significant improvements,with the proposedmethod reducing the annual comprehensive cost by 41.65%and 13.98%,respectively,compared to scenarios without DG and ESS or with only DG integration.Furthermore,it reduces the daily average voltage deviation by 24.35%and 10.24%and daily network losses by 55.72%and 35.71%.展开更多
This paper introduces an Improved Bidirectional Jump Point Search(I-BJPS)algorithm to address the challenges of the traditional Jump Point Search(JPS)in mobile robot path planning.These challenges include excessive no...This paper introduces an Improved Bidirectional Jump Point Search(I-BJPS)algorithm to address the challenges of the traditional Jump Point Search(JPS)in mobile robot path planning.These challenges include excessive node expansions,frequent path inflexion points,slower search times,and a high number of jump points in complex environments with large areas and dense obstacles.Firstly,we improve the heuristic functions in both forward and reverse directions to minimize expansion nodes and search time.We also introduce a node optimization strategy to reduce non-essential nodes so that the path length is optimized.Secondly,we employ a second-order Bezier Curve to smooth turning points,making generated paths more suitable for mobile robot motion requirements.Then,we integrate the Dynamic Window Approach(DWA)to improve path planning safety.Finally,the simulation results demonstrate that the I-BJPS algorithm significantly outperforms both the original unidirectional JPS algorithm and the bidirectional JPS algorithm in terms of search time,the number of path inflexion points,and overall path length,the advantages of the I-BJPS algorithm are particularly pronounced in complex environments.Experimental results from real-world scenarios indicate that the proposed algorithm can efficiently and rapidly generate an optimal path that is safe,collision-free,and well-suited to the robot’s locomotion requirements.展开更多
Combat effectiveness of unmanned aerial vehicle(UAV)formations can be severely affected by the mission execution reliability.During the practical execution phase,there are inevitable risks where UAVs being destroyed o...Combat effectiveness of unmanned aerial vehicle(UAV)formations can be severely affected by the mission execution reliability.During the practical execution phase,there are inevitable risks where UAVs being destroyed or targets failed to be executed.To improve the mission reliability,a resilient mission planning framework integrates task pre-and re-assignment modules is developed in this paper.In the task pre-assignment phase,to guarantee the mission reliability,probability constraints regarding the minimum mission success rate are imposed to establish a multi-objective optimization model.And an improved genetic algorithm with the multi-population mechanism and specifically designed evolutionary operators is used for efficient solution.As in the task-reassignment phase,possible trigger events are first analyzed.A real-time contract net protocol-based algorithm is then proposed to address the corresponding emergency scenario.And the dual objective used in the former phase is adapted into a single objective to keep a consistent combat intention.Three cases of different scales demonstrate that the two modules cooperate well with each other.On the one hand,the pre-assignment module can generate high-reliability mission schedules as an elaborate mathematical model is introduced.On the other hand,the re-assignment module can efficiently respond to various emergencies and adjust the original schedule within a millisecond.The corresponding animation is accessible at bilibili.com/video/BV12t421w7EE for better illustration.展开更多
Under the background of global tourism development,the planning and design of rural tourism landscape in Libo Yaoshan Ancient Village in the buffer zone of a world natural heritage site were discussed.Through the anal...Under the background of global tourism development,the planning and design of rural tourism landscape in Libo Yaoshan Ancient Village in the buffer zone of a world natural heritage site were discussed.Through the analysis of the current resources and characteristics of Yaoshan Ancient Village,the planning and design principles of cultural inheritance and innovation,ecological protection and sustainable development,and integration of landscape diversity and experience based on the concept of global tourism were clarified.A specific planning and design scheme for tourism landscape was put forward,such as creating the entrance service area,core sightseeing area,rural sightseeing area,folk experience area and other functional divisions.Besides,traffic routes should be optimized and adjusted,and the supporting construction of tourism service facilities should be strengthened to comprehensively improve the overall quality of rural tourism landscape of Yaoshan Ancient Village,promote the sustainable development of local rural tourism,and provide useful reference for the planning and design of rural tourism landscape in other similar areas.展开更多
The traditional A^(*)algorithm exhibits a low efficiency in the path planning of unmanned surface vehicles(USVs).In addition,the path planned presents numerous redundant inflection waypoints,and the security is low,wh...The traditional A^(*)algorithm exhibits a low efficiency in the path planning of unmanned surface vehicles(USVs).In addition,the path planned presents numerous redundant inflection waypoints,and the security is low,which is not conducive to the control of USV and also affects navigation safety.In this paper,these problems were addressed through the following improvements.First,the path search angle and security were comprehensively considered,and a security expansion strategy of nodes based on the 5×5 neighborhood was proposed.The A^(*)algorithm search neighborhood was expanded from 3×3 to 5×5,and safe nodes were screened out for extension via the node security expansion strategy.This algorithm can also optimize path search angles while improving path security.Second,the distance from the current node to the target node was introduced into the heuristic function.The efficiency of the A^(*)algorithm was improved,and the path was smoothed using the Floyd algorithm.For the dynamic adjustment of the weight to improve the efficiency of DWA,the distance from the USV to the target point was introduced into the evaluation function of the dynamic-window approach(DWA)algorithm.Finally,combined with the local target point selection strategy,the optimized DWA algorithm was performed for local path planning.The experimental results show the smooth and safe path planned by the fusion algorithm,which can successfully avoid dynamic obstacles and is effective and feasible in path planning for USVs.展开更多
文摘Environmental and ecological problems in the urban-rural integration were analyzed, characteristics of urban green space system introduced, such as excellent landscape eco-structure, distinctive historical and humanistic features, and diversified natural landscape resources, and also challenges pointed out. Evolution, overall spatial structure and conservation concept of conservation-minded urban green space system planning were elaborated, on the basis of which the evaluation system of conservation-minded urban green space system was studied, and it was proposed that mutual relationship between impact factors of compound value and qualitative evaluation factors should be taken into consideration as a whole in evaluating conservation effects of green space system. Quantitative evaluation indexes and qualitative evaluation measures were analyzed, an objective and precise evaluation system for the conservation-minded urban green space system was established by combining qualitative and quantitative analysis to improve ecological environment during the urbanization, and fully show planning concepts of conservation-minded green space system.
文摘This study proposes a novel approach to optimizing individual work schedules for book digitization using mixed-integer programming (MIP). By leveraging the power of MIP solvers, we aimed to minimize the overall digitization time while considering various constraints and process dependencies. The book digitization process involves three key steps: cutting, scanning, and binding. Each step has specific requirements and limitations such as the number of pages that can be processed simultaneously and potential bottlenecks. To address these complexities, we formulate the problem as a one-machine job shop scheduling problem with additional constraints to capture the unique characteristics of book digitization. We conducted a series of experiments to evaluate the performance of our proposed approach. By comparing the optimized schedules with the baseline approach, we demonstrated significant reductions in the overall processing time. In addition, we analyzed the impact of different weighting schemes on the optimization results, highlighting the importance of identifying and prioritizing critical processes. Our findings suggest that MIP-based optimization can be a valuable tool for improving the efficiency of individual work schedules, even in seemingly simple tasks, such as book digitization. By carefully considering specific constraints and objectives, we can save time and leverage resources by carefully considering specific constraints and objectives.
文摘The construction projects’ dynamic and interconnected nature requires a comprehensive understanding of complexity during pre-construction. Traditional tools such as Gantt charts, CPM, and PERT often overlook uncertainties. This study identifies 20 complexity factors through expert interviews and literature, categorising them into six groups. The Analytical Hierarchy Process evaluated the significance of different factors, establishing their corresponding weights to enhance adaptive project scheduling. A system dynamics (SD) model is developed and tested to evaluate the dynamic behaviour of identified complexity factors. The model simulates the impact of complexity on total project duration (TPD), revealing significant deviations from initial deterministic estimates. Data collection and analysis for reliability tests, including normality and Cronbach alpha, to validate the model’s components and expert feedback. Sensitivity analysis confirmed a positive relationship between complexity and project duration, with higher complexity levels resulting in increased TPD. This relationship highlights the inadequacy of static planning approaches and underscores the importance of addressing complexity dynamically. The study provides a framework for enhancing planning systems through system dynamics and recommends expanding the model to ensure broader applicability in diverse construction projects.
文摘Rational laboratory layout design and scientific management systems are key to improving overall laboratory efficiency and safety,providing a solid foundation and guarantee for the smooth progress of scientific research.This article addresses a series of issues such as low testing efficiency caused by unreasonable laboratory layouts,incomplete or outdated equipment configurations affecting testing accuracy,and safety hazards arising from the lack of effective laboratory management systems.It conducts an in-depth exploration of the design and planning strategies for physicochemical laboratories.By proposing specific designs and guidelines for the location selection,functional zoning,and layout requirements of physicochemical laboratories,the aim is to optimize laboratory space utilization,enhance testing efficiency,and ensure the advancement of equipment configurations and the accuracy of testing precision.Simultaneously,it emphasizes the establishment of an effective laboratory management system to prevent and control safety hazards,safeguarding the lives of laboratory personnel and ensuring stable laboratory operations.
文摘Objective:To understand the current situation of career planning awareness and readiness of freshman medical students with a background in digital medicine,and to provide references for optimizing the medical education system and career guidance.Methods:A cross-sectional study was conducted on freshman medical students at a university in Yunnan Province using questionnaire survey.Results:A total of 272 questionnaires were distributed and 264 valid questionnaires were returned,yielding an effective response rate of 97.10%.The average score of digital medical awareness of freshman medical students was(70.50±8.81),and 63.63%of the students had a high awareness(score≧70);The average score of career planning awareness and readiness of freshman medical students was(91.76±14.87),and 60.63%of students had high awareness and readiness(score≧90).Pearson correlation analysis showed that the total score of digital medical awareness was positively correlated with the total score of career planning awareness and readiness(r=0.13,P<0.05).Conclusion:Freshman medical students’career planning awareness and readiness are generally good,but their practical application of digital medical-related skills still needs improvement.It is suggested that schools strengthen the integration of interdisciplinary curriculum,introduce digital vocational training modules,and formulate differentiated guidance strategies for different majors to enhance students’professional competitiveness in the digital medical era.
文摘Village revitalization is a major development strategy in China,where village planning plays as its critical component.Taking village planning of De’an County in Jiangxi Province as an example,this paper explored the significant importance of village planning in promoting rural revitalization along with its corresponding promote mechanisms.Through in-depth research on the detailed situation of village planning and implementation in Jiangxi,this paper summarized that some challenges exist,including backward planning,poor planning consciousness,difficulties in planning implementation.Based on these findings,the paper analyzed the challenges of village land resource scarcity,village images lacking in uniqueness features,and insufficient rural infrastructure construction.Furthermore,it proposed strategies such as taking the lead in planning from the beginning,advancing practical implementation at a high level,adhering to bottom-line thinking,and coordinating high-quality rural land protection and development,applying strategies such as ecological and pleasant living,building villages suitable for living and working,and construction of beautiful countryside,aiming to provide valuable reference for related research fields.
文摘Objective:This study aimed to explore the readiness for advance care planning(ACP)among older adults in Macao’s day service centers and investigate the influencing factors.Methods:A cross-sectional study was conducted from October to December 2022 using a convenience sampling method.A total of 312 older adults were selected from 13 day service centers for older adults in Macao,China.The Advance Care Planning Acceptance Questionnaire and the Family Adaptation,Partnership,Growth,Affection,Resolve(APGAR)Scale were used to survey the older adults.Results:A total of 306 older adults completed the survey.The score for advance care planning readiness was 65.55±10.69,and 59.5%of participants(n=182)were willing to participate in ACP.The family function score was 7.24±2.51,while 70.3%of participants were from a highly functional family.The higher family function indicating a higher readiness for advance care planning(r=0.396,P<0.001).The multiple linear regression analysis indicated that the variables“age,”“knowledge of ACP,”“experience with ACP,”and“received resuscitation of yourself,relatives or friends”combined with“family function”can influence advance care planning readiness among older adults(R^(2)=0.317,F=27.898,P<0.001).Conclusions:Older adults in Macao’s day service centers were willing to engage in ACP.The importance of family involvement is highlighted in the ACP readiness.Health education and improved family communication are vital for promoting ACP,which ensures individuals receive care when they lack the capacity to make that choice.Additionally,healthcare professionals should enhance communication and education with older adults during the medical care process.
基金funded by the Natural Science Basis Research Plan in Shaanxi Province of China(Program No.2023-JC-QN-0659)General Specialized Scientific Research Program of the Shaanxi Provincial Department of Education(Program 23JK0349).
文摘Legged robots have always been a focal point of research for scholars domestically and internationally.Compared to other types of robots,quadruped robots exhibit superior balance and stability,enabling them to adapt effectively to diverse environments and traverse rugged terrains.This makes them well-suited for applications such as search and rescue,exploration,and transportation,with strong environmental adaptability,high flexibility,and broad application prospects.This paper discusses the current state of research on quadruped robots in terms of development status,gait trajectory planning methods,motion control strategies,reinforcement learning applications,and control algorithm integration.It highlights advancements in modeling,optimization,control,and data-driven approaches.The study identifies the adoption of efficient gait planning algorithms,the integration of reinforcement learning-based control technologies,and data-driven methods as key directions for the development of quadruped robots.The aim is to provide theoretical references for researchers in the field of quadruped robotics.
基金supported by the National Key Research and Development Program of China(2022ZD0117501).
文摘Machine learning-assisted retrosynthesis planning aims to utilize machine learning(ML)algorithms to find synthetic pathways for target compounds.In recent years,with the development of artificial intelligence(AI),especially ML,researchers’interest in ML-assisted retrosynthesis planning has rapidly increased,bringing development and opportunities to the field.In this review,we aim to provide a comprehensive understanding of ML-assisted retrosynthesis planning.We first discuss the formal definition and the objective of retrosynthesis planning,and organize a modular framework which includes four modules:data preparation,data preprocessing,pathway generation and evaluation,and pathway verification.Then,we sequentially review the current status of the first three modules(except pathway verification)in the ML-assisted retrosynthesis planning framework,including ideas,methods,and latest progress.Following that,we specifically discuss large language models in retrosynthesis planning.Finally,we summarize the extant challenges that are faced by current ML-assisted retrosynthesis planning research and offer a perspective on future research directions and development.
基金supported in part by the National Natural Science Foundation of China under Grants 62303098 and 62173073in part by China Postdoctoral Science Foundation under Grant 2022M720679+1 种基金in part by the Central University Basic Research Fund of China under Grant N2304021in part by the Liaoning Provincial Science and Technology Plan Project-Technology Innovation Guidance of the Science and Technology Department under Grant 2023JH1/10400011.
文摘Despite its immense potential,the application of digital twin technology in real industrial scenarios still faces numerous challenges.This study focuses on industrial assembly lines in sectors such as microelectronics,pharmaceuticals,and food packaging,where precision and speed are paramount,applying digital twin technology to the robotic assembly process.The innovation of this research lies in the development of a digital twin architecture and system for Delta robots that is suitable for real industrial environments.Based on this system,a deep reinforcement learning algorithm for obstacle avoidance path planning in Delta robots has been developed,significantly enhancing learning efficiency through an improved intermediate reward mechanism.Experiments on communication and interaction between the digital twin system and the physical robot validate the effectiveness of this method.The system not only enhances the integration of digital twin technology,deep reinforcement learning and robotics,offering an efficient solution for path planning and target grasping inDelta robots,but also underscores the transformative potential of digital twin technology in intelligent manufacturing,with extensive applicability across diverse industrial domains.
基金supported in part by the National Natural Science Foundation of China(Nos.52205532 and 624B2077)the National Key Research and Development Program of China(No.2023YFB4302003).
文摘The global demand for effective skin injury treatments has prompted the exploration of tissue engineering solutions.While three-dimensional(3D)bioprinting has shown promise,challenges persist with respect to achieving timely and compatible solutions to treat diverse skin injuries.In situ bioprinting has emerged as a key new technology,since it reduces risks during the implantation of printed scaffolds and demonstrates superior therapeutic effects.However,maintaining printing fidelity during in situ bioprinting remains a critical challenge,particularly with respect to model layering and path planning.This study proposes a novel optimization-based conformal path planning strategy for in situ bioprinting-based repair of complex skin injuries.This strategy employs constrained optimization to identify optimal waypoints on a point cloud-approximated curved surface,thereby ensuring a high degree of similarity between predesigned planar and surface-mapped 3D paths.Furthermore,this method is applicable for skin wound treatments,since it generates 3D-equidistant zigzag curves along surface tangents and enables multi-layer conformal path planning to facilitate the treatment of volumetric injuries.Furthermore,the proposed algorithm was found to be a feasible and effective treatment in a murine back injury model as well as in other complex models,thereby showcasing its potential to guide in situ bioprinting,enhance bioprinting fidelity,and facilitate improvement of clinical outcomes.
文摘BACKGROUND Kidney transplantation is one of the most effective treatments for patients with end-stage renal disease.However,many regions face low deceased donor rates and limited ABO-compatible transplant availability,which increases reliance on living donors.These regional challenges necessitate the implementation of kidney paired donation(KPD)programs to overcome incompatibilities such as ABO mismatch or positive cross-matching,even when suitable and willing donors are available.AIM To evaluate the effectiveness of a single-center domino KPD model in both operational planning and clinical management processes and to assess its impact on clinical outcomes.METHODS Between April 2020 and January 2024,we retrospectively evaluated patients enrolled in our center’s domino kidney transplantation program.Donor-recipient pairs unable to proceed due to ABO incompatibility or positive cross-matching with their own living donors were included.Donors and recipients were assessed based on blood group compatibility,HLA tissue typing,and negative cross-match results.A specialized computer algorithm grouped patients into three-way,fourway,and five-way chains.All surgical procedures were performed on the same day at a single center.RESULTS A total of 169 kidney transplants were performed,forming 52 domino chains.These domino KPD transplants accounted for a notable proportion of our center’s overall transplant activity,which included both living donor kidney transplants and deceased donor transplants.Among these chains,the primary reasons for participation were ABO incompatibility(74%),positive cross-matching(10%),and the desire to improve HLA mismatch(16%).Improved HLA mismatch profiles and high graft survival(96%at 1 year,92%at 3 years)and patient survival(98%at 1 year,94%at 3 years)rates were observed,as well as low acute rejection episodes.CONCLUSION The single-center domino KPD model enhanced transplant opportunities for incompatible donor-recipient pairs while maintaining excellent clinical outcomes.By providing a framework that addresses regional challenges,improves operational efficiency,and optimizes clinical management,this model offers actionable insights to reduce waiting lists and improve patient outcomes.
基金Supported by the Tianjin University of Technology Graduate R esearch Innovation Project(YJ2281).
文摘An improved version of the sparse A^(*)algorithm is proposed to address the common issue of excessive expansion of nodes and failure to consider current ship status and parameters in traditional path planning algorithms.This algorithm considers factors such as initial position and orientation of the ship,safety range,and ship draft to determine the optimal obstacle-avoiding route from the current to the destination point for ship planning.A coordinate transformation algorithm is also applied to convert commonly used latitude and longitude coordinates of ship travel paths to easily utilized and analyzed Cartesian coordinates.The algorithm incorporates a hierarchical chart processing algorithm to handle multilayered chart data.Furthermore,the algorithm considers the impact of ship length on grid size and density when implementing chart gridification,adjusting the grid size and density accordingly based on ship length.Simulation results show that compared to traditional path planning algorithms,the sparse A^(*)algorithm reduces the average number of path points by 25%,decreases the average maximum storage node number by 17%,and raises the average path turning angle by approximately 10°,effectively improving the safety of ship planning paths.
基金funded by the Technology Project of State Grid Jibei Electric Power Supply Co.,Ltd.(Grant Number:52018F240001).
文摘As the development of new power systems accelerates and the impacts of high renewable energy integration and extreme weather intensify,grid-alternative energy storage is garnering increasing attention for its grid-interaction benefits and clear business models.Consequently,assessing the value of grid-alternative energy storage in the systemtransition has become critically important.Considering the performance characteristics of storage,we propose a value assessment frame-work for grid-alternative energy storage,quantifying its non-wires-alternative effects from both cost and benefit perspectives.Building on this,we developed a collaborative planning model for energy storage and transmission grids,aimed at maximizing the economic benefits of storage systems while balancing investment and operational costs.The model considers regional grid interconnections and their interactions with system operation.By participating in system operations,grid-alternative energy storage not only maximizes its own economic benefits but also generates social welfare transfer effects.Furthermore,based on multi-regional interconnected planning,grid-alternative energy storage can reduce system costs by approximately 35%,with the most significant changes observed in generation costs.Multi-regional coordinated planning significantly enhances the sys-tem’s flexibility in regulation.However,when the load factor of interconnection lines between regions remains constant,system operational flexibility tends to decrease,leading to a roughly 28.9%increase in storage investment.Additionally,under regional coordinated planning,the greater the disparity in wind power integration across interconnected regions,the more noticeable the reduction in system costs.
文摘To improve the efficiency and accuracy of path planning for fan inspection tasks in thermal power plants,this paper proposes an intelligent inspection robot path planning scheme based on an improved A^(*)algorithm.The inspection robot utilizes multiple sensors to monitor key parameters of the fans,such as vibration,noise,and bearing temperature,and upload the data to the monitoring center.The robot’s inspection path employs the improved A^(*)algorithm,incorporating obstacle penalty terms,path reconstruction,and smoothing optimization techniques,thereby achieving optimal path planning for the inspection robot in complex environments.Simulation results demonstrate that the improved A^(*)algorithm significantly outperforms the traditional A^(*)algorithm in terms of total path distance,smoothness,and detour rate,effectively improving the execution efficiency of inspection tasks.
基金This research was funded by“Chunhui Program”Collaborative Scientific Research Project of the Ministry of Education of the People’s Republic of China(Project No.HZKY20220242)the S&T Program of Hebei(Project No.225676163GH).
文摘Rational distribution network planning optimizes power flow distribution,reduces grid stress,enhances voltage quality,promotes renewable energy utilization,and reduces costs.This study establishes a distribution network planning model incorporating distributed wind turbines(DWT),distributed photovoltaics(DPV),and energy storage systems(ESS).K-means++is employed to partition the distribution network based on electrical distance.Considering the spatiotemporal correlation of distributed generation(DG)outputs in the same region,a joint output model of DWT and DPV is developed using the Frank-Copula.Due to the model’s high dimensionality,multiple constraints,and mixed-integer characteristics,bilevel programming theory is utilized to structure the model.The model is solved using a mixed-integer particle swarmoptimization algorithm(MIPSO)to determine the optimal location and capacity of DG and ESS integrated into the distribution network to achieve the best economic benefits and operation quality.The proposed bilevel planning method for distribution networks is validated through simulations on the modified IEEE 33-bus system.The results demonstrate significant improvements,with the proposedmethod reducing the annual comprehensive cost by 41.65%and 13.98%,respectively,compared to scenarios without DG and ESS or with only DG integration.Furthermore,it reduces the daily average voltage deviation by 24.35%and 10.24%and daily network losses by 55.72%and 35.71%.
基金supported by the Xinjiang Uygur Autonomous Region Central Guided Local Science and Technology Development Fund Project(No.ZYYD2025QY17).
文摘This paper introduces an Improved Bidirectional Jump Point Search(I-BJPS)algorithm to address the challenges of the traditional Jump Point Search(JPS)in mobile robot path planning.These challenges include excessive node expansions,frequent path inflexion points,slower search times,and a high number of jump points in complex environments with large areas and dense obstacles.Firstly,we improve the heuristic functions in both forward and reverse directions to minimize expansion nodes and search time.We also introduce a node optimization strategy to reduce non-essential nodes so that the path length is optimized.Secondly,we employ a second-order Bezier Curve to smooth turning points,making generated paths more suitable for mobile robot motion requirements.Then,we integrate the Dynamic Window Approach(DWA)to improve path planning safety.Finally,the simulation results demonstrate that the I-BJPS algorithm significantly outperforms both the original unidirectional JPS algorithm and the bidirectional JPS algorithm in terms of search time,the number of path inflexion points,and overall path length,the advantages of the I-BJPS algorithm are particularly pronounced in complex environments.Experimental results from real-world scenarios indicate that the proposed algorithm can efficiently and rapidly generate an optimal path that is safe,collision-free,and well-suited to the robot’s locomotion requirements.
基金supported by the National Key Research and Development Plan(Grant No.2021YFB3302501)the National Natural Science Foundation of China(Grant Nos.12102077,12161076,U2241263).
文摘Combat effectiveness of unmanned aerial vehicle(UAV)formations can be severely affected by the mission execution reliability.During the practical execution phase,there are inevitable risks where UAVs being destroyed or targets failed to be executed.To improve the mission reliability,a resilient mission planning framework integrates task pre-and re-assignment modules is developed in this paper.In the task pre-assignment phase,to guarantee the mission reliability,probability constraints regarding the minimum mission success rate are imposed to establish a multi-objective optimization model.And an improved genetic algorithm with the multi-population mechanism and specifically designed evolutionary operators is used for efficient solution.As in the task-reassignment phase,possible trigger events are first analyzed.A real-time contract net protocol-based algorithm is then proposed to address the corresponding emergency scenario.And the dual objective used in the former phase is adapted into a single objective to keep a consistent combat intention.Three cases of different scales demonstrate that the two modules cooperate well with each other.On the one hand,the pre-assignment module can generate high-reliability mission schedules as an elaborate mathematical model is introduced.On the other hand,the re-assignment module can efficiently respond to various emergencies and adjust the original schedule within a millisecond.The corresponding animation is accessible at bilibili.com/video/BV12t421w7EE for better illustration.
基金Sponsored by the Guizhou Provincial Key Technology R&D Program:A Study on the Conservation Model with Technology and Sustainable Development Demonstration of the World Natural Heritages in Guizhou(No.2202023QKHZC).
文摘Under the background of global tourism development,the planning and design of rural tourism landscape in Libo Yaoshan Ancient Village in the buffer zone of a world natural heritage site were discussed.Through the analysis of the current resources and characteristics of Yaoshan Ancient Village,the planning and design principles of cultural inheritance and innovation,ecological protection and sustainable development,and integration of landscape diversity and experience based on the concept of global tourism were clarified.A specific planning and design scheme for tourism landscape was put forward,such as creating the entrance service area,core sightseeing area,rural sightseeing area,folk experience area and other functional divisions.Besides,traffic routes should be optimized and adjusted,and the supporting construction of tourism service facilities should be strengthened to comprehensively improve the overall quality of rural tourism landscape of Yaoshan Ancient Village,promote the sustainable development of local rural tourism,and provide useful reference for the planning and design of rural tourism landscape in other similar areas.
基金Supported by the EDD of China(No.80912020104)the Science and Technology Commission of Shanghai Municipality(No.22ZR1427700 and No.23692106900).
文摘The traditional A^(*)algorithm exhibits a low efficiency in the path planning of unmanned surface vehicles(USVs).In addition,the path planned presents numerous redundant inflection waypoints,and the security is low,which is not conducive to the control of USV and also affects navigation safety.In this paper,these problems were addressed through the following improvements.First,the path search angle and security were comprehensively considered,and a security expansion strategy of nodes based on the 5×5 neighborhood was proposed.The A^(*)algorithm search neighborhood was expanded from 3×3 to 5×5,and safe nodes were screened out for extension via the node security expansion strategy.This algorithm can also optimize path search angles while improving path security.Second,the distance from the current node to the target node was introduced into the heuristic function.The efficiency of the A^(*)algorithm was improved,and the path was smoothed using the Floyd algorithm.For the dynamic adjustment of the weight to improve the efficiency of DWA,the distance from the USV to the target point was introduced into the evaluation function of the dynamic-window approach(DWA)algorithm.Finally,combined with the local target point selection strategy,the optimized DWA algorithm was performed for local path planning.The experimental results show the smooth and safe path planned by the fusion algorithm,which can successfully avoid dynamic obstacles and is effective and feasible in path planning for USVs.
