BACKGROUND Functional vocal cord disorders can be a differential diagnosis for postoperative upper airway obstruction requiring urgent intervention.However,this may be unfamiliar to anesthesiologists who would favor i...BACKGROUND Functional vocal cord disorders can be a differential diagnosis for postoperative upper airway obstruction requiring urgent intervention.However,this may be unfamiliar to anesthesiologists who would favor inappropriate airway intervention and increased morbidity.CASE SUMMARY A 61-year-old woman underwent cervical laminectomy,followed by laparoscopic cholecystectomy 10 mo later.Despite adequate reversal of neuromuscular blockade,the patient experienced repetitive respiratory difficulty with inspiratory stridor after extubation.After the second operation,the patient was diagnosed with paradoxical vocal fold motion(PVFM)by an otolaryngologist based on the clinical features and fiberoptic bronchoscopy results,and the patient was successfully treated.CONCLUSION PVFM should be considered a differential diagnosis if a patient presents with stridor after general anesthesia.展开更多
This paper deals about a quantitative and qualitative study of the sustained vibration pat-terns of vocal cords with a mulfifunctional glottograph developed by the authors.The glottogramsand their parameters for the m...This paper deals about a quantitative and qualitative study of the sustained vibration pat-terns of vocal cords with a mulfifunctional glottograph developed by the authors.The glottogramsand their parameters for the modal,falsetto,breathy and pressed voices are presented.This paper al-so sets out to explore the influence of the changes in the properties of the vocal tract andfundamental frequency,on vocal cord vibration.Typical clinical results show that the glottographicmethod may be used in the diagnosis and treatment of laryngeal diseases,phonation physiology andevaluation of artistic voice.展开更多
The change of vocal flinction after vocal fold dehydration due to dryness was discussed along with the treatment eHect of different atomizing agents.Forty-eight staffs from The Central Hospital of Wuhan were recniited...The change of vocal flinction after vocal fold dehydration due to dryness was discussed along with the treatment eHect of different atomizing agents.Forty-eight staffs from The Central Hospital of Wuhan were recniited.All volunteers breathed dry air for vocal fold dehydration.After dry air inhalation,the subjects were randomly divided into four groups,with 12 cases each.Three groups were treatment groups,receiving 0.9%nonnal saline(IS),5%hypertonic saline(HS)and double-distilled water(SW)atomizing inhalation therapy,respectively,and the last group was the control group without treatment.Voice data were collected for all subjects before and immediately after dry air inhalation using the Multi-Dimensional Voice Program(MDVP)system.Atomizing inhalation therapy was given 10 min after dry air inhalation,and voice data were collected using MDVP system at the following time points after atomizing inhalation treatment:5 min,20 min,35 min,50 min,65 min,80 min,95 min,110 min.In the control group,voice data were collected at the same time points and compared with those of treatment groups.The vocal function parameters collected before and after dry air inhalation as well as after treatment were subjected to test using SPSS 16.0 software.In the four groups,jitter(fundamental frequency perturbation),shimmer(amplitude perturbation),and amplitude perturbation quotient(APQ)were significantly increased after dry air inhalation(P<0.05).In IS,HS and SW groups,after atomizing inhalation treatment,there was an obvious reduction in jitter,shimmer and APQ,showing significant differences as compared with those after dry air inhalation(P<0.05).Moreover,these parameters were significantly lower than those in the control group(P<0.05).The jitter,shimmer and APQ in the IS group were significantly lower than those in the HS and SW groups(P<0.05).We are led to a con elusion:Vocal fold dehydration induced by dryness can reduce the stability of voice;such decreased voice stability can be improved by atomizing inhalation therapy;without proper treatment,voice stability caused by vocal fold dehydration cannot heal spontaneously;of three atomizing agents namely,IS,HS and SW,IS had the best treatment effect for decreased voice stability caused by vocal fold dehydration.展开更多
<strong>Objective(s):</strong> The aim of this study is to explore if there is a correlation between the typical voice classification and the morphometric characteristics of the vocal folds, using video la...<strong>Objective(s):</strong> The aim of this study is to explore if there is a correlation between the typical voice classification and the morphometric characteristics of the vocal folds, using video laryngeal stroboscopy, on professional singers in Greece. <strong>Methods:</strong> 70 professional singers, 50% men (35 men) and 50% women (35 women), were recruited for this study. A stroboscopic evaluation was prepared for every participant. Additionally, the voice classification and features of individuals were correlated statistically. <strong>Results:</strong> Statistically significant difference were observed between the voice categories and the size of stomatopharynx, the shape of the hard palate, the length of the vocal folds, the width and thickness of the vocal folds, as well as the tone of speech, in male singers. Statistically significant differences were also observed between the voice categories and all the variables except the shape of epiglottis, the color of speech and the shape of the vocal folds, in female singers. <strong>Conclusions:</strong> There is correlation between the morphometric characteristics of the vocal folds and the voice categories.展开更多
In this work,a three dimensional(3D)convolutional neural network(CNN)model based on image slices of various normal and pathological vocal folds is proposed for accurate and efficient prediction of glottal flows.The 3D...In this work,a three dimensional(3D)convolutional neural network(CNN)model based on image slices of various normal and pathological vocal folds is proposed for accurate and efficient prediction of glottal flows.The 3D CNN model is composed of the feature extraction block and regression block.The feature extraction block is capable of learning low dimensional features from the high dimensional image data of the glottal shape,and the regression block is employed to flatten the output from the feature extraction block and obtain the desired glottal flow data.The input image data is the condensed set of 2D image slices captured in the axial plane of the 3D vocal folds,where these glottal shapes are synthesized based on the equations of normal vibration modes.The output flow data is the corresponding flow rate,averaged glottal pressure and nodal pressure distributions over the glottal surface.The 3D CNN model is built to establish the mapping between the input image data and output flow data.The ground-truth flow variables of each glottal shape in the training and test datasets are obtained by a high-fidelity sharp-interface immersed-boundary solver.The proposed model is trained to predict the concerned flow variables for glottal shapes in the test set.The present 3D CNN model is more efficient than traditional Computational Fluid Dynamics(CFD)models while the accuracy can still be retained,and more powerful than previous data-driven prediction models because more details of the glottal flow can be provided.The prediction performance of the trained 3D CNN model in accuracy and efficiency indicates that this model could be promising for future clinical applications.展开更多
The geometric and biomechanical properties of the larynx strongly influence voice quality and efficiency. A physical understanding of phonation natures in pathological conditions is important for predictions of how vo...The geometric and biomechanical properties of the larynx strongly influence voice quality and efficiency. A physical understanding of phonation natures in pathological conditions is important for predictions of how voice disorders can be treated using therapy and rehabilitation. Here, we present a continuum-based numerical model of phonation that considers complex fluid-structure interactions occurring in the airway. This model considers a three-dimensional geometry of vocal folds, muscle contractions, and viscoelastic properties to provide a realistic framework of phonation. The vocal fold motion is coupled to an unsteady compressible respiratory flow, allowing numerical simulations of normal and diseased phonations to derive clear relationships between actual laryngeal structures and model parameters such as muscle activity. As a pilot analysis of diseased phonation, we model vocal nodules, the mass lesions that can appear bilaterally on both sides of the vocal folds. Comparison of simulations with and without the nodules demonstrates how the lesions affect vocal fold motion, consequently restricting voice quality. Furthermore, we found that the minimum lung pressure required for voice production increases as nodules move closer to the center of the vocal fold. Thus, simulations using the developed model may provide essential insight into complex phonation phenomena and further elucidate the etiologic mechanisms of voice disorders.展开更多
文摘BACKGROUND Functional vocal cord disorders can be a differential diagnosis for postoperative upper airway obstruction requiring urgent intervention.However,this may be unfamiliar to anesthesiologists who would favor inappropriate airway intervention and increased morbidity.CASE SUMMARY A 61-year-old woman underwent cervical laminectomy,followed by laparoscopic cholecystectomy 10 mo later.Despite adequate reversal of neuromuscular blockade,the patient experienced repetitive respiratory difficulty with inspiratory stridor after extubation.After the second operation,the patient was diagnosed with paradoxical vocal fold motion(PVFM)by an otolaryngologist based on the clinical features and fiberoptic bronchoscopy results,and the patient was successfully treated.CONCLUSION PVFM should be considered a differential diagnosis if a patient presents with stridor after general anesthesia.
基金The project was supported by the National Natural Science Foundation of China No.6881030
文摘This paper deals about a quantitative and qualitative study of the sustained vibration pat-terns of vocal cords with a mulfifunctional glottograph developed by the authors.The glottogramsand their parameters for the modal,falsetto,breathy and pressed voices are presented.This paper al-so sets out to explore the influence of the changes in the properties of the vocal tract andfundamental frequency,on vocal cord vibration.Typical clinical results show that the glottographicmethod may be used in the diagnosis and treatment of laryngeal diseases,phonation physiology andevaluation of artistic voice.
文摘The change of vocal flinction after vocal fold dehydration due to dryness was discussed along with the treatment eHect of different atomizing agents.Forty-eight staffs from The Central Hospital of Wuhan were recniited.All volunteers breathed dry air for vocal fold dehydration.After dry air inhalation,the subjects were randomly divided into four groups,with 12 cases each.Three groups were treatment groups,receiving 0.9%nonnal saline(IS),5%hypertonic saline(HS)and double-distilled water(SW)atomizing inhalation therapy,respectively,and the last group was the control group without treatment.Voice data were collected for all subjects before and immediately after dry air inhalation using the Multi-Dimensional Voice Program(MDVP)system.Atomizing inhalation therapy was given 10 min after dry air inhalation,and voice data were collected using MDVP system at the following time points after atomizing inhalation treatment:5 min,20 min,35 min,50 min,65 min,80 min,95 min,110 min.In the control group,voice data were collected at the same time points and compared with those of treatment groups.The vocal function parameters collected before and after dry air inhalation as well as after treatment were subjected to test using SPSS 16.0 software.In the four groups,jitter(fundamental frequency perturbation),shimmer(amplitude perturbation),and amplitude perturbation quotient(APQ)were significantly increased after dry air inhalation(P<0.05).In IS,HS and SW groups,after atomizing inhalation treatment,there was an obvious reduction in jitter,shimmer and APQ,showing significant differences as compared with those after dry air inhalation(P<0.05).Moreover,these parameters were significantly lower than those in the control group(P<0.05).The jitter,shimmer and APQ in the IS group were significantly lower than those in the HS and SW groups(P<0.05).We are led to a con elusion:Vocal fold dehydration induced by dryness can reduce the stability of voice;such decreased voice stability can be improved by atomizing inhalation therapy;without proper treatment,voice stability caused by vocal fold dehydration cannot heal spontaneously;of three atomizing agents namely,IS,HS and SW,IS had the best treatment effect for decreased voice stability caused by vocal fold dehydration.
文摘<strong>Objective(s):</strong> The aim of this study is to explore if there is a correlation between the typical voice classification and the morphometric characteristics of the vocal folds, using video laryngeal stroboscopy, on professional singers in Greece. <strong>Methods:</strong> 70 professional singers, 50% men (35 men) and 50% women (35 women), were recruited for this study. A stroboscopic evaluation was prepared for every participant. Additionally, the voice classification and features of individuals were correlated statistically. <strong>Results:</strong> Statistically significant difference were observed between the voice categories and the size of stomatopharynx, the shape of the hard palate, the length of the vocal folds, the width and thickness of the vocal folds, as well as the tone of speech, in male singers. Statistically significant differences were also observed between the voice categories and all the variables except the shape of epiglottis, the color of speech and the shape of the vocal folds, in female singers. <strong>Conclusions:</strong> There is correlation between the morphometric characteristics of the vocal folds and the voice categories.
基金supported by the Open Project of Key Laboratory of Computational Aerodynamics,AVIC Aerodynamics Research Institute(Grant No.YL2022XFX0409).
文摘In this work,a three dimensional(3D)convolutional neural network(CNN)model based on image slices of various normal and pathological vocal folds is proposed for accurate and efficient prediction of glottal flows.The 3D CNN model is composed of the feature extraction block and regression block.The feature extraction block is capable of learning low dimensional features from the high dimensional image data of the glottal shape,and the regression block is employed to flatten the output from the feature extraction block and obtain the desired glottal flow data.The input image data is the condensed set of 2D image slices captured in the axial plane of the 3D vocal folds,where these glottal shapes are synthesized based on the equations of normal vibration modes.The output flow data is the corresponding flow rate,averaged glottal pressure and nodal pressure distributions over the glottal surface.The 3D CNN model is built to establish the mapping between the input image data and output flow data.The ground-truth flow variables of each glottal shape in the training and test datasets are obtained by a high-fidelity sharp-interface immersed-boundary solver.The proposed model is trained to predict the concerned flow variables for glottal shapes in the test set.The present 3D CNN model is more efficient than traditional Computational Fluid Dynamics(CFD)models while the accuracy can still be retained,and more powerful than previous data-driven prediction models because more details of the glottal flow can be provided.The prediction performance of the trained 3D CNN model in accuracy and efficiency indicates that this model could be promising for future clinical applications.
文摘The geometric and biomechanical properties of the larynx strongly influence voice quality and efficiency. A physical understanding of phonation natures in pathological conditions is important for predictions of how voice disorders can be treated using therapy and rehabilitation. Here, we present a continuum-based numerical model of phonation that considers complex fluid-structure interactions occurring in the airway. This model considers a three-dimensional geometry of vocal folds, muscle contractions, and viscoelastic properties to provide a realistic framework of phonation. The vocal fold motion is coupled to an unsteady compressible respiratory flow, allowing numerical simulations of normal and diseased phonations to derive clear relationships between actual laryngeal structures and model parameters such as muscle activity. As a pilot analysis of diseased phonation, we model vocal nodules, the mass lesions that can appear bilaterally on both sides of the vocal folds. Comparison of simulations with and without the nodules demonstrates how the lesions affect vocal fold motion, consequently restricting voice quality. Furthermore, we found that the minimum lung pressure required for voice production increases as nodules move closer to the center of the vocal fold. Thus, simulations using the developed model may provide essential insight into complex phonation phenomena and further elucidate the etiologic mechanisms of voice disorders.
