Archaeologists exploring a well-preserved shipwreck prove a forgotten marine trade route The first probing of the ancient merchant vessel Nanhai No.1 after the wreck was put into a museum pool of simulated seawater su...Archaeologists exploring a well-preserved shipwreck prove a forgotten marine trade route The first probing of the ancient merchant vessel Nanhai No.1 after the wreck was put into a museum pool of simulated seawater successfully recovered porcelain and stone artifacts from its cabin on September 27.展开更多
Given the increased circulation time after fishing,a series of changes take place in live clams,leading to a deterioration in quality even after death.Thus,in this study,we aimed to explore the optimal mode of transpo...Given the increased circulation time after fishing,a series of changes take place in live clams,leading to a deterioration in quality even after death.Thus,in this study,we aimed to explore the optimal mode of transportation of clams.The container for holding clams was reformed,and a water circulation temperature control system was established.The physiological responses of clams during anhydrous and watery transportation at two temperatures(4 and 15℃)were investigated based on the aforementioned system.When comparing the transportation patterns after 3 d of transport,a higher survival rate was observed at 4℃(97%)than at 15℃(63%)in the anhydrous transportation groups and a lower survival rate was observed at 4℃(93%)than at 15℃(99%)in the watery transportation groups.In addition,the glycogen content,condition index(CI),and adenylate energy charge(A.E.C)value were higher at4℃((40.87±0.99)mg g^(-1),13.71%±0.50%and 57.45%±1.60%)than at 15℃((30.54±0.81)mg g^(-1),9.09%±0.30%and 43.12%±1.65%)in the anhydrous transportation groups.In the watery transportation groups,a lower glycogen content,CI,and A.E.C.value were observed at 4℃((33.78±0.84)mg g^(-1),9.78%±0.50%and 64.65%±1.25%)than at 15℃((41.53±0.93)mg g^(-1),12.72%±0.83%and 71.58%±1.27%).Results from this study show that anhydrous transportation(4℃)is the optimal transport condition for clams to maintain a high quality and good physiological conditions.Thus,this study will be particularly useful for establishing shellfish transportation systems.展开更多
The establishment and realization of the VPP calucation’s model for the functional analytic theory are discussed in this paper.Functional analyzing method is a theoretical model of the VPP calculation which can elimi...The establishment and realization of the VPP calucation’s model for the functional analytic theory are discussed in this paper.Functional analyzing method is a theoretical model of the VPP calculation which can eliminate the influence of the sail and board’s size skillfully,so it can be regarded as a brief standard of the sailboard’s VPP results.As a brief watery dynamical model,resistance on board can be regarded as a direct proportion to the square of the boat-velocity.The boat-velocities at the state of six wind-velocities(3m/s-8m/s) with angles of 25°-180° are obtained by calculating,which provides an important gist of the sailing-route’s selection in upwind-sailing.展开更多
Background: Diarrhoea is the second leading cause of childhood mortality in children under five years old. Water is a major contributing risk factor for this disease that is a common illness and a global killer. Mater...Background: Diarrhoea is the second leading cause of childhood mortality in children under five years old. Water is a major contributing risk factor for this disease that is a common illness and a global killer. Material and Methods: Water samples from different areas of Karachi were collected and were processed by MPN technique to evaluate the presence of microbiological substances. Results: Out of the processed samples, 64% were positive for the presence of mix enteric pathogen from different areas of Karachi;from Bhens colony, 74% were positive for the presence of fecal coli forms, among which 4% were positive for EHEC isolated from storage tank and water tank. Conclusion: The abovementioned results reflect the presence of organisms of public health importance in different sources of drinking water. According to WHO guidelines, there should be zero tolerance of these organisms in water.展开更多
The zoonotic cryptosporidiosis is globally distributed,one of the major diarrheal diseases in humans and animals.Cryptosporidium oocysts are also one of the major environmental concerns,making it a pathogen that fits ...The zoonotic cryptosporidiosis is globally distributed,one of the major diarrheal diseases in humans and animals.Cryptosporidium oocysts are also one of the major environmental concerns,making it a pathogen that fits well into the One Health concept.Despite its importance,fully effective drugs are not yet available.Anti-cryptosporidial drug discovery has historically faced many unusual challenges attributed to unique parasite biology and technical burdens.While significant progresses have been made recently,anti-cryptosporidial drug discovery still faces a major obstacle:identification of systemic drugs that can be absorbed by patients experiencing watery diarrhea and effectively pass through electron-dense(ED)band at the parasite-host cell interface to act on the epicellular parasite.There may be a need to develop an in vitro assay to effectively screen hits/leads for their capability to cross ED band.In the meantime,non-systemic drugs with strong mucoadhesive properties for extended gastrointestinal exposure may represent another direction in developing anti-cryptosporidial therapeutics.For developing both systemic and non-systemic drugs,a non-ruminant animal model exhibiting diarrheal symptoms suitable for routine evaluation of drug absorption and anti-cryptosporidial efficacy may be very helpful.展开更多
文摘Archaeologists exploring a well-preserved shipwreck prove a forgotten marine trade route The first probing of the ancient merchant vessel Nanhai No.1 after the wreck was put into a museum pool of simulated seawater successfully recovered porcelain and stone artifacts from its cabin on September 27.
基金This study is supported by the National Key R&D Program of China(No.2018YFD0901004)the Innovation Team Project of Hebei Province Modern Agricultural Industry Technology System(No.HBCT2018170207)+1 种基金the Innovation Center of Hebei Agricultural Products Processing Technology(No.199676183H)the Modern Agricultural Industry Technology System(No.CARS-49).
文摘Given the increased circulation time after fishing,a series of changes take place in live clams,leading to a deterioration in quality even after death.Thus,in this study,we aimed to explore the optimal mode of transportation of clams.The container for holding clams was reformed,and a water circulation temperature control system was established.The physiological responses of clams during anhydrous and watery transportation at two temperatures(4 and 15℃)were investigated based on the aforementioned system.When comparing the transportation patterns after 3 d of transport,a higher survival rate was observed at 4℃(97%)than at 15℃(63%)in the anhydrous transportation groups and a lower survival rate was observed at 4℃(93%)than at 15℃(99%)in the watery transportation groups.In addition,the glycogen content,condition index(CI),and adenylate energy charge(A.E.C)value were higher at4℃((40.87±0.99)mg g^(-1),13.71%±0.50%and 57.45%±1.60%)than at 15℃((30.54±0.81)mg g^(-1),9.09%±0.30%and 43.12%±1.65%)in the anhydrous transportation groups.In the watery transportation groups,a lower glycogen content,CI,and A.E.C.value were observed at 4℃((33.78±0.84)mg g^(-1),9.78%±0.50%and 64.65%±1.25%)than at 15℃((41.53±0.93)mg g^(-1),12.72%±0.83%and 71.58%±1.27%).Results from this study show that anhydrous transportation(4℃)is the optimal transport condition for clams to maintain a high quality and good physiological conditions.Thus,this study will be particularly useful for establishing shellfish transportation systems.
基金This work was supported by the key sur mounting event of General Administration of Sport of China for 2004 Olympics:Research of the optimal incline-angle and route in sailboard sports(03056).
文摘The establishment and realization of the VPP calucation’s model for the functional analytic theory are discussed in this paper.Functional analyzing method is a theoretical model of the VPP calculation which can eliminate the influence of the sail and board’s size skillfully,so it can be regarded as a brief standard of the sailboard’s VPP results.As a brief watery dynamical model,resistance on board can be regarded as a direct proportion to the square of the boat-velocity.The boat-velocities at the state of six wind-velocities(3m/s-8m/s) with angles of 25°-180° are obtained by calculating,which provides an important gist of the sailing-route’s selection in upwind-sailing.
文摘Background: Diarrhoea is the second leading cause of childhood mortality in children under five years old. Water is a major contributing risk factor for this disease that is a common illness and a global killer. Material and Methods: Water samples from different areas of Karachi were collected and were processed by MPN technique to evaluate the presence of microbiological substances. Results: Out of the processed samples, 64% were positive for the presence of mix enteric pathogen from different areas of Karachi;from Bhens colony, 74% were positive for the presence of fecal coli forms, among which 4% were positive for EHEC isolated from storage tank and water tank. Conclusion: The abovementioned results reflect the presence of organisms of public health importance in different sources of drinking water. According to WHO guidelines, there should be zero tolerance of these organisms in water.
基金supported in part by grants from the National Key Research and Development Program of China 2017YFC1601206(J.Y.)the National Institutes of Health,USA R01AI125362(G.D.C.).
文摘The zoonotic cryptosporidiosis is globally distributed,one of the major diarrheal diseases in humans and animals.Cryptosporidium oocysts are also one of the major environmental concerns,making it a pathogen that fits well into the One Health concept.Despite its importance,fully effective drugs are not yet available.Anti-cryptosporidial drug discovery has historically faced many unusual challenges attributed to unique parasite biology and technical burdens.While significant progresses have been made recently,anti-cryptosporidial drug discovery still faces a major obstacle:identification of systemic drugs that can be absorbed by patients experiencing watery diarrhea and effectively pass through electron-dense(ED)band at the parasite-host cell interface to act on the epicellular parasite.There may be a need to develop an in vitro assay to effectively screen hits/leads for their capability to cross ED band.In the meantime,non-systemic drugs with strong mucoadhesive properties for extended gastrointestinal exposure may represent another direction in developing anti-cryptosporidial therapeutics.For developing both systemic and non-systemic drugs,a non-ruminant animal model exhibiting diarrheal symptoms suitable for routine evaluation of drug absorption and anti-cryptosporidial efficacy may be very helpful.
