Introduction: Indicators of maternal health are often used to evaluate the social development and overall health of a population, as well as the accessibility of health services. Among these indicators, the Potential ...Introduction: Indicators of maternal health are often used to evaluate the social development and overall health of a population, as well as the accessibility of health services. Among these indicators, the Potential Years of Life Lost, which is associated with maternal deaths, is useful for the definition of priorities, monitoring, evaluation, and intervention, identifying the highest risk groups. Objective: To analyze the Potential Years of Life Lost by maternal death in Santa Catarina in 2000 and 2014. Method: An Ecological study with exploratory spatial analysis was conducted with data obtained from the Information System on Mortality and Live Births. Results: In the Information System, 35 maternal deaths in the year 2000 were identified and 24 in 2014. The total estimated years of life lost were 845 years in 2000 and 780 years in 2014, dominated by direct obstetric causes. In 2000, women who died lost, on average, 39.8 years of life;and 41.5 years in 2014. Conclusion: The spatial pattern observed in 2000 highlights areas of high risk in different regions of Santa Catarina. The greatest loss of years occurred in younger women, confirming the need to prevent and control maternal mortality and review strategies for compliance with public policies in the State.展开更多
Background:Colorectal cancer(CRC)is the fourth cause of cancer death in China.We aimed to provide national and subnational estimates and changes of CRC premature mortality burden during 2005–2020.Methods:Data from mu...Background:Colorectal cancer(CRC)is the fourth cause of cancer death in China.We aimed to provide national and subnational estimates and changes of CRC premature mortality burden during 2005–2020.Methods:Data from multi-source on the basis of the national surveillance mortality system were used to estimate mortality and years of life lost(YLL)of CRC in the Chinese population during 2005–2020.Estimates were generated and compared for 31 provincial-level administrative divisions in China.Results:Estimated CRC deaths increased from 111.41 thousand in 2005 to 178.02 thousand in 2020;age-standardized mortality rate decreased from 10.01 per 100,000 in 2005 to 9.68 per 100,000 in 2020.Substantial reduction in CRC premature mortality burden,as measured by age-standardized YLL rate,was observed with a reduction of 10.20%nationwide.Marked differences were observed in the geographical patterns of provincial units,and they appeared to be obvious in areas with higher economic development.Population aging was the dominant driver which contributed to the increase in CRC deaths,followed by population growth and age-specific mortality change.Conclusions:Substantial discrepancies were observed in the premature mortality burden of CRC across China.Targeted considerations were needed to promote a healthy lifestyle,expand cost-effective CRC early screening and diagnosis,and improve medical treatment to reduce CRC mortality among high-risk populations and regions with inadequate healthcare resources.展开更多
Although numerous studies have investigated premature deaths attributable to temperature,effects of temperature on years of life lost(YLL)remain unclear.We estimated the relationship between temperatures and YLL,and q...Although numerous studies have investigated premature deaths attributable to temperature,effects of temperature on years of life lost(YLL)remain unclear.We estimated the relationship between temperatures and YLL,and quantified the YLL per death caused by temperature in China.We collected daily meteorological and mortality data,and calculated the daily YLL values for 364 locations(2013–2017 in Yunnan,Guangdong,Hunan,Zhejiang,and Jilin provinces,and 2006–2011 in other locations)in China.A time-series design with a distributed lag nonlinear model was first employed to estimate the location-specific associations between temperature and YLL rates(YLL/100,000 population),and a multivariate meta-analysis model was used to pool location-specific associations.Then,YLL per death caused by temperatures was calculated.The temperature and YLL rates consistently showed U-shaped associations.A mean of 1.02(95%confidence interval:0.67,1.37)YLL per death was attributable to temperature.Cold temperature caused 0.98 YLL per death with most from moderate cold(0.84).The mean YLL per death was higher in those with cardiovascular diseases(1.14),males(1.15),younger age categories(1.31 in people aged 65–74 years),and in central China(1.34)than in those with respiratory diseases(0.47),females(0.87),older people(0.85 in people R75 years old),and northern China(0.64)or southern China(1.19).The mortality burden was modified by annual temperature and temperature variability,relative humidity,latitude,longitude,altitude,education attainment,and central heating use.Temperatures caused substantial YLL per death in China,which was modified by demographic and regional characteristics.展开更多
Background The rise in suicides among children aged 10–14 years demands urgent attention globally.This study aims to assess the global burden of suicide-related deaths in this age group from 1990 to 2019,considering ...Background The rise in suicides among children aged 10–14 years demands urgent attention globally.This study aims to assess the global burden of suicide-related deaths in this age group from 1990 to 2019,considering factors such as sex,geography,and sociodemographics,to inform prevention strategies and interventions.Methods The data from Global Burden of Disease 2019,encompassing 204 countries and territories,were analyzed to investigate deaths and years of life lost(YLLs)due to suicide among children aged 10–14 years.Statistical analyses,including mortality rates,YLLs,and the sociodemographic index(SDI),were conducted using standardized tools.Results In 2019,a total of 8327[95%uncertainty interval(UI)=7073–9685]children aged 10–14 years died globally due to suicide,with a mortality rate of 1.30(95%UI=1.10–1.51)per 100,000.The rates varied across countries/territories ranging between 0.05(95%UI=0.02–0.10)in South Africa and 7.49(95%UI=5.13–10.57)in Greenland.The contribution of suicide-related deaths to all-cause mortality ranged from 0.07%(95%UI=0.04%–0.15%)in South Africa to 33.02%(95%UI=24.36%–41.53%)in Greenland.Worldwide,there were approximately 636,196(95%UI=540,383–740,009)YLLs due to suicide,with a rate of 99.07(95%UI=84.15–115.23)per 100,000.The association between SDI and suicide-related deaths was evident,with higher contributions observed in countries with higher SDI.Conclusions This study reveals a concerning global burden of suicide-related deaths among children aged 10–14 years.Despite progress in reducing mortality rates,suicide remains a significant issue.While overall rates have declined,the percentage of deaths caused by suicide in this age group is increasing.展开更多
Although exposure to air pollution increases the risk of premature mortality and years of life lost(YLL),the effects of daily air quality improvement to the life expectancy of respiratory diseases remained unclear.We ...Although exposure to air pollution increases the risk of premature mortality and years of life lost(YLL),the effects of daily air quality improvement to the life expectancy of respiratory diseases remained unclear.We applied a generalized additive model(GAM)to assess the associations between daily PM_(2.5) exposure and YLL from respiratory diseases in 96 Chinese cities during 2013–2016.We further estimated the avoidable YLL,potential gains in life expectancy,and the attributable fraction by assuming dailyPM_(2.5) concentration decrease to the air quality standards of China and World Health Organization.Regional and national results were generated by random-effects meta-analysis.A total of 861,494 total respiratory diseases and 586,962 chronic obstructive pulmonary disease(COPD)caused death from 96 Chinese cities were recorded during study period.Each 10 mg/m3 increase of PM_(2.5) in 3-day moving average(lag02)was associated with 0.16(95%CI:0.08,0.24)years increment in life expectancy from total respiratory diseases.The highest effect was observed in Southwest region with 0.42(95%CI:0.22,0.62)years increase in life expectancy.By attaining the WHO's Air Quality Guidelines,we estimated that an average of 782.09(95%CI:438.29,1125.89)YLLs caused by total respiratory death in each city could be avoided,which corresponded to 1.15%(95%CI:0.67%,1.64%)of the overall YLLs,and 0.12(95%CI:0.07,0.17)years increment in life expectancy.The results of COPD were generally consistent with total respiratory diseases.Our findings indicate that reduction in daily PM_(2.5) concentrations might lead to longer life expectancy from respiratory death.展开更多
AIM: To determine the extent of colorectal cancer (CRC) mortality and the association between demographic characteristics and CRC mortality in Inner Mongolia.
The burden of injuries is underestimated to an evengreater extent in developing countries than inindustrialized countries. The objective of this paper is toanalyze injuries and diseases in the monitored work place
Biliary tract carcinoma(BTC)is a group of malignant tumors that originate in the digestive system and occurs with a high incidence in China.Few consistent and comparable assessments of BTC disease burden have been con...Biliary tract carcinoma(BTC)is a group of malignant tumors that originate in the digestive system and occurs with a high incidence in China.Few consistent and comparable assessments of BTC disease burden have been conducted at national or subnational levels,and little is known about the demographic,temporal,and geographic patterns of epidemiological characteristics and disease burden of BTC in China.The incidence,mortality,disability-adjusted life-years(DALYs),years of life lost(YLLs)due to premature death and years lived with disability(YLDs)of BTC were comprehensively examined by age,sex,and calendar year in the Chinese population,using the methodological framework and analytical strategies used for the 2021 Global Burden of Disease study.All-age incidence increased from 17,077 to 51,720between 1990 and 2021,and the age-standardized incidence rate rose by 13.62%;all-age deaths increased from 17,251 to 37,833,but the age-standardized mortality rate fell by nearly one-fifth.The DALYs rose by 89.57%while the age-standardized DALY rate fell by 23.24%.Variations of the tendencies in BTC burden were found between sexes and age groups.Data for each provincial region indicate that coastal eastern provincial regions have higher incidence and YLD levels,whereas northern provincial regions have higher mortality,DALY,and YLL levels.The proportions of DALYs attributable to high body mass index(BMI)illustrate the growing attribution obesity has made,and high BMI usually puts more burden on northern provincial regions.These results provide evidence to support precise,targeted,and customed public health strategies aimed at enhancing biliary tract health among the Chinese population.展开更多
基金financed in part by the Coordenacao de Aperfeicoamento de Pessoal de Nível Superior-Brasil(CAPES)-Finance Code 001.
文摘Introduction: Indicators of maternal health are often used to evaluate the social development and overall health of a population, as well as the accessibility of health services. Among these indicators, the Potential Years of Life Lost, which is associated with maternal deaths, is useful for the definition of priorities, monitoring, evaluation, and intervention, identifying the highest risk groups. Objective: To analyze the Potential Years of Life Lost by maternal death in Santa Catarina in 2000 and 2014. Method: An Ecological study with exploratory spatial analysis was conducted with data obtained from the Information System on Mortality and Live Births. Results: In the Information System, 35 maternal deaths in the year 2000 were identified and 24 in 2014. The total estimated years of life lost were 845 years in 2000 and 780 years in 2014, dominated by direct obstetric causes. In 2000, women who died lost, on average, 39.8 years of life;and 41.5 years in 2014. Conclusion: The spatial pattern observed in 2000 highlights areas of high risk in different regions of Santa Catarina. The greatest loss of years occurred in younger women, confirming the need to prevent and control maternal mortality and review strategies for compliance with public policies in the State.
基金the National Key Research&Development Program of the Ministry of Science and Technology of the People’s Republic of China(No.2018YFC1315301)Taikang Yicai Public Health and Epidemic Control Fund.
文摘Background:Colorectal cancer(CRC)is the fourth cause of cancer death in China.We aimed to provide national and subnational estimates and changes of CRC premature mortality burden during 2005–2020.Methods:Data from multi-source on the basis of the national surveillance mortality system were used to estimate mortality and years of life lost(YLL)of CRC in the Chinese population during 2005–2020.Estimates were generated and compared for 31 provincial-level administrative divisions in China.Results:Estimated CRC deaths increased from 111.41 thousand in 2005 to 178.02 thousand in 2020;age-standardized mortality rate decreased from 10.01 per 100,000 in 2005 to 9.68 per 100,000 in 2020.Substantial reduction in CRC premature mortality burden,as measured by age-standardized YLL rate,was observed with a reduction of 10.20%nationwide.Marked differences were observed in the geographical patterns of provincial units,and they appeared to be obvious in areas with higher economic development.Population aging was the dominant driver which contributed to the increase in CRC deaths,followed by population growth and age-specific mortality change.Conclusions:Substantial discrepancies were observed in the premature mortality burden of CRC across China.Targeted considerations were needed to promote a healthy lifestyle,expand cost-effective CRC early screening and diagnosis,and improve medical treatment to reduce CRC mortality among high-risk populations and regions with inadequate healthcare resources.
基金We thank Professor Antonio Gasparrini for providing assistance during statistical analysis.This work was supported by the National Key Research and Development Program of China(2018YFA0606200)Guangzhou Science and Technology Project(201704020194)+3 种基金and the Guangdong Health Innovation Platform.The funders were not involved in the research and preparation of the article,including study designcollection,analysis,and interpretation of datawriting of the articleand the decision to submit it for publication.
文摘Although numerous studies have investigated premature deaths attributable to temperature,effects of temperature on years of life lost(YLL)remain unclear.We estimated the relationship between temperatures and YLL,and quantified the YLL per death caused by temperature in China.We collected daily meteorological and mortality data,and calculated the daily YLL values for 364 locations(2013–2017 in Yunnan,Guangdong,Hunan,Zhejiang,and Jilin provinces,and 2006–2011 in other locations)in China.A time-series design with a distributed lag nonlinear model was first employed to estimate the location-specific associations between temperature and YLL rates(YLL/100,000 population),and a multivariate meta-analysis model was used to pool location-specific associations.Then,YLL per death caused by temperatures was calculated.The temperature and YLL rates consistently showed U-shaped associations.A mean of 1.02(95%confidence interval:0.67,1.37)YLL per death was attributable to temperature.Cold temperature caused 0.98 YLL per death with most from moderate cold(0.84).The mean YLL per death was higher in those with cardiovascular diseases(1.14),males(1.15),younger age categories(1.31 in people aged 65–74 years),and in central China(1.34)than in those with respiratory diseases(0.47),females(0.87),older people(0.85 in people R75 years old),and northern China(0.64)or southern China(1.19).The mortality burden was modified by annual temperature and temperature variability,relative humidity,latitude,longitude,altitude,education attainment,and central heating use.Temperatures caused substantial YLL per death in China,which was modified by demographic and regional characteristics.
基金This research received no specific grants from any funding agency in the public,commercial,or not-for-profit sectors.
文摘Background The rise in suicides among children aged 10–14 years demands urgent attention globally.This study aims to assess the global burden of suicide-related deaths in this age group from 1990 to 2019,considering factors such as sex,geography,and sociodemographics,to inform prevention strategies and interventions.Methods The data from Global Burden of Disease 2019,encompassing 204 countries and territories,were analyzed to investigate deaths and years of life lost(YLLs)due to suicide among children aged 10–14 years.Statistical analyses,including mortality rates,YLLs,and the sociodemographic index(SDI),were conducted using standardized tools.Results In 2019,a total of 8327[95%uncertainty interval(UI)=7073–9685]children aged 10–14 years died globally due to suicide,with a mortality rate of 1.30(95%UI=1.10–1.51)per 100,000.The rates varied across countries/territories ranging between 0.05(95%UI=0.02–0.10)in South Africa and 7.49(95%UI=5.13–10.57)in Greenland.The contribution of suicide-related deaths to all-cause mortality ranged from 0.07%(95%UI=0.04%–0.15%)in South Africa to 33.02%(95%UI=24.36%–41.53%)in Greenland.Worldwide,there were approximately 636,196(95%UI=540,383–740,009)YLLs due to suicide,with a rate of 99.07(95%UI=84.15–115.23)per 100,000.The association between SDI and suicide-related deaths was evident,with higher contributions observed in countries with higher SDI.Conclusions This study reveals a concerning global burden of suicide-related deaths among children aged 10–14 years.Despite progress in reducing mortality rates,suicide remains a significant issue.While overall rates have declined,the percentage of deaths caused by suicide in this age group is increasing.
基金supported by the National Key R&D Program of China(Grant No.2016YFC0206501)the National Natural Science Foundation of China(Grant No.81972993)+1 种基金the Fundamental Research Funds for the Central Universities(Grant No.20ykpy86)the Guangdong Basic and Applied Basic Research Foundation(Grant No.2019A1515110003).
文摘Although exposure to air pollution increases the risk of premature mortality and years of life lost(YLL),the effects of daily air quality improvement to the life expectancy of respiratory diseases remained unclear.We applied a generalized additive model(GAM)to assess the associations between daily PM_(2.5) exposure and YLL from respiratory diseases in 96 Chinese cities during 2013–2016.We further estimated the avoidable YLL,potential gains in life expectancy,and the attributable fraction by assuming dailyPM_(2.5) concentration decrease to the air quality standards of China and World Health Organization.Regional and national results were generated by random-effects meta-analysis.A total of 861,494 total respiratory diseases and 586,962 chronic obstructive pulmonary disease(COPD)caused death from 96 Chinese cities were recorded during study period.Each 10 mg/m3 increase of PM_(2.5) in 3-day moving average(lag02)was associated with 0.16(95%CI:0.08,0.24)years increment in life expectancy from total respiratory diseases.The highest effect was observed in Southwest region with 0.42(95%CI:0.22,0.62)years increase in life expectancy.By attaining the WHO's Air Quality Guidelines,we estimated that an average of 782.09(95%CI:438.29,1125.89)YLLs caused by total respiratory death in each city could be avoided,which corresponded to 1.15%(95%CI:0.67%,1.64%)of the overall YLLs,and 0.12(95%CI:0.07,0.17)years increment in life expectancy.The results of COPD were generally consistent with total respiratory diseases.Our findings indicate that reduction in daily PM_(2.5) concentrations might lead to longer life expectancy from respiratory death.
基金Supported by Inner Mongolia Autonomous Region Colleges and Universities of Science and Technology Research Projects,No.NJZY13415Inner Mongolia Medical University Technology Million Project,No.NY2011BW006Natural Science Foundation of Inner Mongolia in China,No.2013MS1124
文摘AIM: To determine the extent of colorectal cancer (CRC) mortality and the association between demographic characteristics and CRC mortality in Inner Mongolia.
文摘The burden of injuries is underestimated to an evengreater extent in developing countries than inindustrialized countries. The objective of this paper is toanalyze injuries and diseases in the monitored work place
基金supported by the Key Program of Shanghai Science and Technology Commission(YDZX20193100004049)National Natural Science Foundation of China(82273016 and 82303937)+2 种基金Open Project of State Key Laboratory of Oncogenes and Related Genes(KF2120)National Key Project of Research and Development Program of China(2021YFC2500404 and 2021YFC2500405)the University-level Scientific Fund of Shanghai University of Medicine and Health Sciences(SSF-24-1602)。
文摘Biliary tract carcinoma(BTC)is a group of malignant tumors that originate in the digestive system and occurs with a high incidence in China.Few consistent and comparable assessments of BTC disease burden have been conducted at national or subnational levels,and little is known about the demographic,temporal,and geographic patterns of epidemiological characteristics and disease burden of BTC in China.The incidence,mortality,disability-adjusted life-years(DALYs),years of life lost(YLLs)due to premature death and years lived with disability(YLDs)of BTC were comprehensively examined by age,sex,and calendar year in the Chinese population,using the methodological framework and analytical strategies used for the 2021 Global Burden of Disease study.All-age incidence increased from 17,077 to 51,720between 1990 and 2021,and the age-standardized incidence rate rose by 13.62%;all-age deaths increased from 17,251 to 37,833,but the age-standardized mortality rate fell by nearly one-fifth.The DALYs rose by 89.57%while the age-standardized DALY rate fell by 23.24%.Variations of the tendencies in BTC burden were found between sexes and age groups.Data for each provincial region indicate that coastal eastern provincial regions have higher incidence and YLD levels,whereas northern provincial regions have higher mortality,DALY,and YLL levels.The proportions of DALYs attributable to high body mass index(BMI)illustrate the growing attribution obesity has made,and high BMI usually puts more burden on northern provincial regions.These results provide evidence to support precise,targeted,and customed public health strategies aimed at enhancing biliary tract health among the Chinese population.
