Background:Alcohol and illicit drugs(AID)continue to be a major global health concern.Although preventable,AID is linked to millions of deaths annually worldwide.The situation is particularly grave for young people,wi...Background:Alcohol and illicit drugs(AID)continue to be a major global health concern.Although preventable,AID is linked to millions of deaths annually worldwide.The situation is particularly grave for young people,with AID being a major direct risk factor for disability-adjusted youth life-years lost and death.It further contributes to assaults,road crashes,accidental poisoning,and suicide,leading to long-term issues and public health concerns.Objective:This study aimed at disclosing current AID prevalence data for Argentinian,Bulgarian,Chilean and Romanian youth.It shed light on the predictors of AID in young people from those countries.Method:The study used an online survey to gather data from people aged 18 to 25(n=1,297).The survey was underpinned by the theory of planned behaviour(TPB).Predictors were investigated separately for drinking alcohol and using illicit drugs.Results:Our data revealed that across the four target countries,49%to 90%of the participants drank alcohol,and 8%to 35%used illicit drugs in the past three months.Between 20%and 91%of them intended to drink,and between 8%and 31%intended to use illicit drugs in the following three months.Our TPB model predicted statistically significant(P<0.001)amounts of variance in drinking alcohol(between 61%and 72%)and using illicit drugs(between 20.3%and 74.4%).Intention was consistent in significantly predicting both behaviours.Evidence around the predictive validity of self-efficacy,age and gender was mixed across the investigated countries.Conclusion:This research provided an update on the scarce AID epidemiological data.It also supplied evidence about what theoretically-informed measures might be useful targets of interventions in the case of Argentina,Bulgaria,Chile and Romania.This new knowledge of understanding substance abuse determinants and prevalence may help researchers and practitioners better meet young people's health prevention needs.展开更多
Background: Diabetic retinopathy is among the most common diabetic complications, and is one of the leading causes of blindness in the world. Recent studies have linked vitamin D to the pathogenesis of diabetes and th...Background: Diabetic retinopathy is among the most common diabetic complications, and is one of the leading causes of blindness in the world. Recent studies have linked vitamin D to the pathogenesis of diabetes and there is growing evidence that vitamin D can interfere with the mechanisms involved in diabetes and its complications. Despite improvements in treatment, diabetic retinopathy remains a significant complication of type 1 diabetes mellitus. Identification of early treatable predictors of diabetic retinopathy such as vitamin D deficiency, may allow more aggressive management of those at high risk. Purpose: To assess the association of vitamin D deficiency with diabetic retinopathy in young people with type 1 diabetes mellitus. Design: Observational study with case control design. Method: 60 young people with type 1 diabetes aged between 11 to 24 years were included in this study. Among them, 30-young people have diabetic retinopathy and 30-young people do not have diabetic retinopathy. Purposive sampling technique was applied as per inclusion criteria. Statistical analysis of the results was done by using computer-based software, SPSS version 26. P value of less than 0.05 was considered as statistically significant. Results: Vitamin D deficiency was present in 83% of the young people with diabetic retinopathy and in 53% without diabetic retinopathy. The mean vitamin D level in young people with and without diabetic retinopathy was 17.38 ± 3.77 ng/ml and 20.15 ± 5.06 ng/ml respectively and the difference was statistically significant (p = 0.019). Vitamin D deficiency was increased with the severity of diabetic retinopathy. Univariate and multivariate logistic regression showed vitamin D deficiency was independently associated with diabetic retinopathy with a crude odds ratio of 5.69 with a p value of 0.008 and adjusted odds ratio of 16.08 with a p value of 0.002 respectively. Conclusion: Result of the study revealed that vitamin D deficiency was strongly associated with diabetic retinopathy in young people with type 1 diabetes mellitus.展开更多
Despite the acceptance of physical activity （PA） being integral to a young person＇s health, children with disability often exhibit low levels of PA. In young people with cystic fibrosis （CF） the importance of exe...Despite the acceptance of physical activity （PA） being integral to a young person＇s health, children with disability often exhibit low levels of PA. In young people with cystic fibrosis （CF） the importance of exercise and daily PA is acknowledged by clinicians and their support teams, however, there is a lack of knowledge related to its prescription. CF is a recessive genetic disorder affecting the lung, pancreas and sweat glands. CF is the most common life shortening genetic disease in the Caucasian population for which there is no cure. In the UK, CF affects over 9000 people, with 4000 under 16 years of age. Only about half of the CF population can expect to live beyond 40 years of age. Besides drug therapies, rehabilitative exercise programmes form an important component of treatment and long term exercise programmes are considered positive treatment strategies, but all lack any detailed prescriptive information. Several reviews and editorials have highlighted the lack of evidence based research in PA and exercise training in young people with CF; but advocate a greater need for understanding the role of exercise in therapeutic interventions. The purpose of this review is to update the reader on the current recommendations and evidence in PA and exercise training for young people with CE These developments have extended our understanding of PA and exercise training in children and adolescents with CF, and its implementation in the management of this chronic disease.展开更多
The coronavirus pandemic has affected all facets of our lives and all ages and social strata worldwide.Measures have been taken to protect against the spread of the virus,such as more rigorous hand hygiene,the use of ...The coronavirus pandemic has affected all facets of our lives and all ages and social strata worldwide.Measures have been taken to protect against the spread of the virus,such as more rigorous hand hygiene,the use of face masks and social distancing.However,the focus has often been on young people,who have been seen as a group lacking sufficient respect for government-imposed measures.This review outlines the preventive measures that have been taken in different countries and discusses their specific impact on young people and adolescents,taking into account the developmental stage and concrete needs of this age group.It summarizes those studies that have provided information on compliance with preventive measures by young people and adolescents,concluding that although compliance levels among this age group are lower than among older adults,the general view of youths as non-compliant is not consistent with real,objective data.The review also summarizes different views regarding the possible reasons for this lower level of compliance,taking into account both social(gender and age)and personal factors(personality,empathy,prosociality,self-control,cognitive styles and motivations),and discusses the practical implications of these findings for the future.展开更多
This study examined the relationship between sexual risk behavior and HIV counselling and testing uptake among young people in Nigeria. Probability sampling technique was used to obtain a sample of 10,091 respondents ...This study examined the relationship between sexual risk behavior and HIV counselling and testing uptake among young people in Nigeria. Probability sampling technique was used to obtain a sample of 10,091 respondents (ages 15 to 24 years) for the study. The multistage cluster sampling was used to select suitable young people with known probability. Data were collected throughout Nigeria between September and December 2012 from 32,543 households (rural = 22,192;urban = 10,351) using structured and semi-structured questionnaires. The data were summed using descriptive statistics. Frequencies and percentages;measures of central tendencies were used to answer the research question while nonparametric test such as chi-square was used to analyze non-normally distributed data at 0.5 level of significance. Results of data analysis indicated that sexual risk behaviors comprised three variables: sex with multiple partners, intergenerational sex (sex with partners 10 years older), and transactional sex. The results of the chi-square test of association between sex with multiple partners and HCT uptake showed that there was no statistically significant relationship between sex with multiple partners and HCT uptake among young people ages 15 to 24 years in Nigeria. It was among others recommended that sexually active young people in Nigeria should use protection against HIV infection.展开更多
Since the city of Chongqing became a municipality on 14th March, 1997, the structure of Chongqing population has undergone tremendous changes. Especially the young, born after the 1980s, will play an important part in...Since the city of Chongqing became a municipality on 14th March, 1997, the structure of Chongqing population has undergone tremendous changes. Especially the young, born after the 1980s, will play an important part in the future housing market. So it seems quite urgem to effectively satisfy the housing needs of young people. Massive research and practices indicate that the housing industrialization conserves the environment, improves quality and reduces cost of housing and is among the most effective ways to boost sustainable development of housing industry. The main objective of the paper is to discuss how to meet the growing housing demands of the young and concludes that housing with recreation, sports and other ancillary facilities will be better fit to the young to rent or to own. Furthermore, an analysis of the Chongqing housing market potential of young people＇s wish to rent or to purchase satisfactory housing demonstrates that some real estate investors may be failing to exploit serious opportunities that could arise from providing service to the young. And this case study of meeting the changing housing needs of the young may help accelerate the process of housing industrialization in Chongqing as well as providing a useful study concerning housing industry.展开更多
This paper is part of a wider project being carried out by the Research Group Literary Education, Culture and Society, which has been subsidised by the Ministry of University of Spain. Our project＇s main aim is the c...This paper is part of a wider project being carried out by the Research Group Literary Education, Culture and Society, which has been subsidised by the Ministry of University of Spain. Our project＇s main aim is the close study of three closely interrelated phenomena, globalisation, exclusion and multiculturality, in order to determine the influences on the children and young people Literature. We intend in this paper to show the results of a first research made in a smaller corpus in order to better draw up the entire project.展开更多
This study examined the relationship between HIV counselling and testing (HCT) awareness and HCT uptake among young people in Nigeria and their implications for social change. The study is a quantitative research guid...This study examined the relationship between HIV counselling and testing (HCT) awareness and HCT uptake among young people in Nigeria and their implications for social change. The study is a quantitative research guided by one research question and one hypothesis. The target population comprised young people in Nigeria ages 15 to 24 years because the focus of this study was to identify the factors affecting HCT uptake among young people in this age cohort. The representative sample was obtained from the updated master sample frame of rural and urban zones developed by the National Population Commission in Nigeria. This master sample frame was a national survey that comprised all 36 states in Nigeria. Probability sampling technique was used to obtain a sample of 10,091 respondents (ages 15 to 24 years) for the study. The multistage cluster sampling was used to select suitable young people with known probability. Data were collected throughout Nigeria between September and December 2012 from 32,543 households (rural = 22,192;urban = 10,351) using structured and semi-structured questionnaires. The individual questionnaires asked about household characteristics, background characteristics of the respondents. Data were analyzed by inputting them into SPSS v21.0 for analysis and then coded them for each participant. The data were summed using descriptive statistics. Frequencies and percentages;measures of central tendencies were used to answer the research question while nonparametric tests such as chi-square were used to analyze non-normally distributed data at 0.5 level of significance. The results of the chi-square test of association between HCT awareness and HCT uptake showed that there was a statistically significant relationship between HCT awareness and HCT uptake among young people ages 15 to 24 years in Nigeria, X<sup>2</sup> (1, n = 8916) = 306.66, p < 0.001. In other words, knowledge of the availability of HCT services may have influenced the possibility that the participants would use them. Among others, it was recommended that government should examine the efficacy of HCT treatments in Nigeria, along with conducting a demographic analysis of the at-risk population.展开更多
What impressed you most during your stay in China？ At the invitation of Chinese leaders. I came to China in 2007. My trip gave me a chance to learn from China＇s experience educating youngergenerations. During this t...What impressed you most during your stay in China？ At the invitation of Chinese leaders. I came to China in 2007. My trip gave me a chance to learn from China＇s experience educating youngergenerations. During this time. many things impressed me a lot, especial- ly the patriotism of Chinese people.展开更多
Objective:To investigate the differences in risk factors and prognosis between young and elderly patients with acute ST-segment elevation myocardial infarction(STEMI)so as to provide a basis for the prevention of youn...Objective:To investigate the differences in risk factors and prognosis between young and elderly patients with acute ST-segment elevation myocardial infarction(STEMI)so as to provide a basis for the prevention of young patients with acute STEMI.Methods:Patients initially diagnosed with STEMI in the 920"Hospital of Joint Logistic Support Force of PLA from January 1,2018 to December 31,2022 were retrospectively enrolled in this study.A total of 235 STEMI patients aged≤45 years old and 532 STEMI patients aged≥65 years old were screened.The baseline characteristics,laboratory indicators,clinical characteristics,coronary angiography,SYNTAX score and major adverse cardiovascular events(MACE)during 1-year follow-up were analyzed and compared.Results:A total of 767 STEMI patients were enrolled,including 235 in the young group and 532 in the elderly group.Among the STEM patients in the young group,224 cases were male,and smoking and drinking were common.Compared with the elderly group,the young group had shorter hospital stays and more family history of ischemic heart disease(IHD).The level of low-density lipoprotein in the young group was higher than that in the old group,while the level of high-density lipoprotein in the young group was lower than that in the old group.The level of high uric acid and homocysteine in the young group was significantly higher than that in the old group.The main cause of STEMI in the young group was fatigue,and the most common symptom was angina pectoris.Coronary angiography showed that single vessel disease was more common in the young group than in the elderly group,and the lesion in the young group was the left anterior descending artery.The SYNTAX score was significantly lower in the young group than in the elderly group according to the anatomical characteristics of coronary artery disease.In the forest plot,diabetes mellitus and a family history of IHD showed a trend of major adverse cardiovascular events(MACE)in both groups.Conclusion:Males,smokers,alcohol drinkers and family history of ischemic heart disease are more common in young patients.Common risk factors include fatigue,hyperuricemia,hyperlipidemia and so on.In addition,age itself is an independent risk factor.Management of diabetes,hyperuricemia,and homocysteine levels is essential to reduce the incidence of cardiovascular events in young patients.By controlling these factors,the incidence of young patients with acute STEMI can be effectively prevented and the corresponding prevention and treatment basis can be provided.展开更多
BACKGROUND Psychological problems affect economic development.However,there is a huge gap between mental health service resources and mental health service needs.Existing mental health service technology and platforms...BACKGROUND Psychological problems affect economic development.However,there is a huge gap between mental health service resources and mental health service needs.Existing mental health service technology and platforms cannot meet all the diverse mental health needs of people.Smart medicine is a new medical system based online that can effectively improve the quality and efficiency of medical services and make mental health services accessible.AIM To explore the level of intelligent medical use among young and middle-aged people and its correlation with psychological factors.METHODS Convenience sampling was used to select 200 young and middle-aged patients with medical experience at the Third People's Hospital of Chengdu between January 2022 and January 2023 as the research subjects.The general condition Questionnaire,Eysenck Personality Questionnaire,Symptom Checklist-90,General Health Questionnaire,and Smart Medical Service Use Intention Questionnaire were used to collect data.Pearson’s correlation was used to analyze the correlation between the participants’willingness to use smart medical services and their personality characteristics,psychological symptoms,and mental health.RESULTS The results revealed that the mental health of young and middle-aged people was poor,and some had psycho-logical problems such as anxiety,depression,and physical discomfort.Familiarity,acceptance,and usage of smart healthcare in this population are at a medium level,and these levels correlate with psychological characteristics.Acceptance was positively correlated with E,and negatively correlated with P,anxiety,fear,anxiety/insomnia,and social dysfunction.The degree of use was negatively correlated with P,obsessive-compulsive symptoms,depression,anxiety,hostility,paranoia,and somatic symptoms.CONCLUSION The familiarity,acceptance,and usage of smart medical services among the middle-aged and young groups are related to various psychological characteristics.展开更多
BACKGROUND Stroke has become one of the most serious life-threatening diseases due to its high morbidity,disability,recurrence and mortality rates.AIM To explore the intervention effect of multi-disciplinary treatment...BACKGROUND Stroke has become one of the most serious life-threatening diseases due to its high morbidity,disability,recurrence and mortality rates.AIM To explore the intervention effect of multi-disciplinary treatment(MDT)extended nursing model on negative emotions and quality of life of young patients with post-stroke.METHODS A total of 60 young stroke patients who were hospitalized in the neurology department of our hospital from January 2020 to December 2021 were selected and randomly divided into a control group and an experimental group,with 30 patients in each group.The control group used the conventional care model and the experimental group used the MDT extended nursing model.After the inhospital and 3-mo post-discharge interventions,the differences in negative emotions and quality of life scores between the two groups were evaluated and analyzed at the time of admission,at the time of discharge and after discharge,respectively.RESULTS There are no statistically significant differences in the negative emotions scores between the two groups at admission,while there are statistically significant differences in the negative emotions scores within each group at admission and discharge,at discharge and post-discharge,and at discharge and post-discharge.In addition,the negative emotions scores were all statistically significant at discharge and after discharge when compared between the two groups.There was no statistically significant difference in quality of life scores at the time of admission between the two groups,and the difference between quality of life scores at the time of admission and discharge,at the time of discharge and post-discharge,and at the time of admission and post-discharge for each group of patients was statistically significant.CONCLUSION The MDT extended nursing mode can improve the negative emotion of patients and improve their quality of life.Therefore,it can be applied in future clinical practice and is worthy of promotion.展开更多
Objective:To investigate the correlation of variables between dominant and non-dominant eyes in healthy young people.Methods:300 cases(600 eyes)of healthy young volunteers recruited in our hospital from March 2020 to ...Objective:To investigate the correlation of variables between dominant and non-dominant eyes in healthy young people.Methods:300 cases(600 eyes)of healthy young volunteers recruited in our hospital from March 2020 to February 2022were selected as the research objects.The general data of the volunteers were collected and the dominant eye,diopter,biological parameters and retinal blood flow density were detected.We compared all the test indexes of volunteers with different dominant eyes,and compared the refractive parameters,biological parameters and retinal blood flow density between the dominant and non-dominant eyes of volunteers.Results:Among the 300volunteers,62.67%(188/300)had the right eye as the dominant eye and 37.33%(112/300)had the left eye as the dominant eye.There was no significant difference in gender,BMI and equivalent spherical lens(SE)among the subjects with different dominant eyes(P>0.05).The SE and spherical diopter(S)of dominant eye were higher than that of non-dominant eye(P<0.05),but there was no significant difference between the dominant and non-dominant eye(C)(P>0.05);There was no significant difference in SE and C between dominant and non-dominant eye in volunteers with SE difference≤0.5 D and 0.51-1.25 D(P>0.05),and spherical diopter(S)of dominant eye was higher than that of non-dominant eye(P<0.05);The difference of SE was 1.26-2.00 D,>2.00 D,the SE and spherical diopter(S)of dominant eye were higher than those of non-dominant eye(P<0.05),but there was no significant difference between the dominant and non-dominant eye C(P>0.05).The levels of RA and CA in the dominant eye of 300 volunteers were lower than those in the non-dominant eye.The RA and CA levels of the dominant eye were lower than those of the non-dominant eye in volunteers with RA difference≤0.50 D,0.51-1.25 D,1.26-2.00 D,>2.00 D(P<0.05).There was no significant difference in the levels of axial length(AL),central corneal thickness(CCT),anterior chamber depth(ACD)and lens thickness(LT)between the dominant and non-dominant eyes(P>0.05).The levels of superficial retinal capillary layer(SVC),deep retinal capillary layer(DVC)and mean retinal blood flow density(RET)in dominant eyes were lower than those in non-dominant eyes.The level of AC in non-dominant eyes was higher than that in non-dominant eyes(P<0.05).Conclusion:The dominant eye of healthy young people is mostly the right eye,which has nothing to do with gender,age and BMI.Meanwhile,the biological parameters between the dominant and non-dominant eye were basically the same,the mean retinal blood flow density of the dominant eye was lower than that of the non-dominant eye,but its AC was higher than that of the non-dominant eye.展开更多
BACKGROUND The incidence rate of cerebral infarction in young people is increasing day by day,the age of onset tends to be younger,and its internal pathogenesis and mechanism are very complicated,which leads to greate...BACKGROUND The incidence rate of cerebral infarction in young people is increasing day by day,the age of onset tends to be younger,and its internal pathogenesis and mechanism are very complicated,which leads to greater difficulties in treatment.Therefore,it is essential to analyze the key pathway that affects the onset of cerebral infarction in young people from the perspective of genetics.AIM To compare the differentially expressed genes in the brain tissue of young and aged rats with middle cerebral artery occlusion and to analyse their effect on the key signalling pathway involved in the development of cerebral ischaemia in young rats.METHODS The Gene Expression Omnibus 2R online analysis tool was used to analyse the differentially expressed genes in the GSE166162 dataset regarding the development of cerebral ischaemia in young and aged groups of rats.DAVID 6.8 software was further used to filter the differentially expressed genes.These genes were subjected to Gene Ontology(GO)function analysis and Kyoto Encyclopedia of Genes and Genomes(KEGG)pathway enrichment analysis to determine the key gene pathway that affects the occurrence of cerebral ischaemia in young rats.RESULTS Thirty-five differentially expressed genes(such as Igf2,Col1a2,and Sfrp1)were obtained;73 GO enrichment analysis pathways are mainly involved in biological processes such as drug response,amino acid stimulation response,blood vessel development,various signalling pathways,and enzyme regulation.They are involved in molecular functions such as drug binding,protein binding,dopamine binding,metal ion binding,and dopamine neurotransmitter receptor activity.KEGG pathway enrichment analysis showed a significantly enriched pathway:The cyclic adenosine monophosphate(c-AMP)signalling pathway.CONCLUSION The c-AMP signalling pathway might be the key pathway in the intervention of cerebral infarction in young people.展开更多
This study investigates mental health literacy among young and middle-aged urban and rural residents and the differences in mental health literacy,perceived social support and subjective well-being.From January to Feb...This study investigates mental health literacy among young and middle-aged urban and rural residents and the differences in mental health literacy,perceived social support and subjective well-being.From January to February 2022,620 participants(320 rural and 300 urban residents)from three provinces of China were selected by con-venience sampling.A general data questionnaire,mental health literacy scale,perceived social support scale and subjective well-being scale were administered.The mental health literacy scores of urban residents were 3.34±0.57 and those of rural residents were 2.73±0.79.The results of multiple regression analysis showed that the mental health literacy scores of rural residents were more significant than those of urban residents in terms of sex and age,while urban residents’mental health literacy scores were more significant than those of rural resi-dents in terms of monthly income.Mental health literacy,perceived social support and subjective well-being of young and middle-aged urban and rural residents were all positively correlated(P<0.01).While the level of mental health literacy is better among urban residents than rural residents,perceived social support plays a partial mediating role between mental health literacy and subjective well-being of both urban and rural residents,and should be the focus of researchers seeking to improve the level of well-being of residents.展开更多
Sexually transmitted diseases （STDs） are among the first ten causes of unpleasant diseases in young adult males in developing countries and the second major cause of unpleasant diseases in young adult women. Adolesc...Sexually transmitted diseases （STDs） are among the first ten causes of unpleasant diseases in young adult males in developing countries and the second major cause of unpleasant diseases in young adult women. Adolescents and young adults （15-24 years old） make up only 25% of the sexually active population, but represent almost 50% of all new acquired STDs. In general, STDs are epidemics and present an enormous health and economic consequences. An adequate screening for STDs should be done on a routine basis in every part of the world. Many STDs are asymptomatic and therefore can difficult to control. The purpose of reporting of STDs is to ensure that persons who are infected will be quickly diagnosed and appropriately treated to control the spread of infection and also so that partners are notified, tested and appropriately treated. It is estimated that reported cases of STDs represent only 50%-80% of reportable STD infections in the United States, reflecting limited screening and low disease reporting. High-risk sexual behavior is a highly contributive factor of this process as it often leads to teenage pregnancies and HIV/AIDS. One possible explanation for this behavior is that people do not have enough information about the transmission of STDs or ignore the precautions required for safe sex. Approximately 60% of new HIV infections worldwide occur in young people. The frequency of high-risk behaviors among youths may also be influenced by opportunity to engage in them, particularly the amount of time that they are unsupervised by adults. However, in diagnosing and treating these patients, we can effectively prevent the spread of HIV/AIDS. Individuals infected with STDs are 5-10 times more likely than uninfected individuals to acquire or transmit HIV through sexual contact. The breaking of the genital tract lining or skin creates a portal of entry for HIV and, hence, HIV-infected individuals with other STDs are more likely to shed HIV in their genital secretions. To date, the condom is the most effective method available for males for protection against STDs. It is important to control STDs, and prevention can be the key of this process. Prevention can be achieved through education of the population, identification of symptomatic and asymptomatic people, and effective diagnosis and treatment of these patients and their partners.展开更多
BACKGROUND:Coffee is commonly consumed among young people in China. However,consumers are rarely aware of physically adverse effects as a result of excessive consumption of caffeine.DATA SOURCES:A literature search us...BACKGROUND:Coffee is commonly consumed among young people in China. However,consumers are rarely aware of physically adverse effects as a result of excessive consumption of caffeine.DATA SOURCES:A literature search using multiple databases was performed for articles published with concentration on meta-analyses,systematic reviews,and randomized controlled trials.RESULTS:Excess coffee consumption is also a risk of primary cardiac arrest especially in young people. Treatment modalities include activated charcoals,beta-blockers,vasopressin and hemodialysis when necessary.CONCLUSION:Coffee consumers should be advised not to routinely take more than moderate coffee.展开更多
This project was supported by the Department of Antidrug Policies of the Italian Government＇s Presidency Council and it was undertaken by the Forensic Toxicology Division of the University of Florence, in order to id...This project was supported by the Department of Antidrug Policies of the Italian Government＇s Presidency Council and it was undertaken by the Forensic Toxicology Division of the University of Florence, in order to identify the age of onset of abuse of alcohol, caffeine and nicotine, through a scientific approach. The study involved 874 volunteer students aged between 13 and 16 years donating a small lock of their hair. The toxicological researches were performed with gas chromatography-mass spectrometer and liquid chromatography-tandem mass spectrometer instrumentations, on 50 mg of hair （3/4 cm proximal）, detecting： FAEE （fatty acids ethyl esters） and EtG （ethyl glucuronide） as markers of alcohol intake; nicotine and cotinine; caffeine. A self-reported questionnaire was also submitted. The main results showed that 17.6% drinks alcohol （3% is a ＂heavy drinkers＂）, 43.5% ingests more than an espresso/day （21.4% more than 2 espresso/day） and 24.3% is an active smokers （17.0% of ＂heavy smokers＂）. This study depicted a worrisome picture due to the early contact of the adolescents with these substance; moreover it demonstrated that the knowledge about this phenomenon by means of scientific evidences （not only by self-reported questionnaires）, is the only basis for its comprehension and for planning effective prevention strategies.展开更多
The Paediatric Observation Priority Score (POPS) is a bespoke assessment tool for use in Paediatric Emergency Departments incorporating traditional physiological parameters alongside more subjective observational crit...The Paediatric Observation Priority Score (POPS) is a bespoke assessment tool for use in Paediatric Emergency Departments incorporating traditional physiological parameters alongside more subjective observational criteria. Initial performance characteristics of POPS were analysed in a convenience sample of 936 presentations to ED. Triage on the basis of gut instinct parameters identified an additional 261 patients deemed of lowest acuity compared to analysis by physiology scores. Resource consumption increased with increasing acuity on presentation. POPS shows promise in assisting in the assessment process of children presenting to Emergency Departments. Inclusion of subjective triage criteria helps contextualise the physiological parameter scoring by using the experience of staff conducting triage. Initial interpretation of presenting physiology gives a more informed assessment of initial acuity, and thus is better able to identify a child who can be safely managed in the community. The system also allows for rapid detection of those most unwell.展开更多
This study in Gadarif State,Sudan,analyzes the crucial role of youth in conflict resolution and peace building efforts amidst the ongoing crisis.Findings reveal that youth,facing economic,environmental,and security ch...This study in Gadarif State,Sudan,analyzes the crucial role of youth in conflict resolution and peace building efforts amidst the ongoing crisis.Findings reveal that youth,facing economic,environmental,and security challenges,actively engage in peacemaking through initiatives,emergency rooms,and cultural programs,contributing to social cohesion and combatting hate speech.Despite their willingness to build peace,they encounter obstacles like the lack of training programs,limited support,and marginalization in policy-making processes.Recommendations emphasize the necessity of empowering youth through training programs,enhancing government support,and addressing negative perceptions from older generations towards youth contributions.Conclusively,prioritizing youth issues and fostering their participation in peace building initiatives are essential for sustainable peace and social harmony in Gadarif State.展开更多
文摘Background:Alcohol and illicit drugs(AID)continue to be a major global health concern.Although preventable,AID is linked to millions of deaths annually worldwide.The situation is particularly grave for young people,with AID being a major direct risk factor for disability-adjusted youth life-years lost and death.It further contributes to assaults,road crashes,accidental poisoning,and suicide,leading to long-term issues and public health concerns.Objective:This study aimed at disclosing current AID prevalence data for Argentinian,Bulgarian,Chilean and Romanian youth.It shed light on the predictors of AID in young people from those countries.Method:The study used an online survey to gather data from people aged 18 to 25(n=1,297).The survey was underpinned by the theory of planned behaviour(TPB).Predictors were investigated separately for drinking alcohol and using illicit drugs.Results:Our data revealed that across the four target countries,49%to 90%of the participants drank alcohol,and 8%to 35%used illicit drugs in the past three months.Between 20%and 91%of them intended to drink,and between 8%and 31%intended to use illicit drugs in the following three months.Our TPB model predicted statistically significant(P<0.001)amounts of variance in drinking alcohol(between 61%and 72%)and using illicit drugs(between 20.3%and 74.4%).Intention was consistent in significantly predicting both behaviours.Evidence around the predictive validity of self-efficacy,age and gender was mixed across the investigated countries.Conclusion:This research provided an update on the scarce AID epidemiological data.It also supplied evidence about what theoretically-informed measures might be useful targets of interventions in the case of Argentina,Bulgaria,Chile and Romania.This new knowledge of understanding substance abuse determinants and prevalence may help researchers and practitioners better meet young people's health prevention needs.
文摘Background: Diabetic retinopathy is among the most common diabetic complications, and is one of the leading causes of blindness in the world. Recent studies have linked vitamin D to the pathogenesis of diabetes and there is growing evidence that vitamin D can interfere with the mechanisms involved in diabetes and its complications. Despite improvements in treatment, diabetic retinopathy remains a significant complication of type 1 diabetes mellitus. Identification of early treatable predictors of diabetic retinopathy such as vitamin D deficiency, may allow more aggressive management of those at high risk. Purpose: To assess the association of vitamin D deficiency with diabetic retinopathy in young people with type 1 diabetes mellitus. Design: Observational study with case control design. Method: 60 young people with type 1 diabetes aged between 11 to 24 years were included in this study. Among them, 30-young people have diabetic retinopathy and 30-young people do not have diabetic retinopathy. Purposive sampling technique was applied as per inclusion criteria. Statistical analysis of the results was done by using computer-based software, SPSS version 26. P value of less than 0.05 was considered as statistically significant. Results: Vitamin D deficiency was present in 83% of the young people with diabetic retinopathy and in 53% without diabetic retinopathy. The mean vitamin D level in young people with and without diabetic retinopathy was 17.38 ± 3.77 ng/ml and 20.15 ± 5.06 ng/ml respectively and the difference was statistically significant (p = 0.019). Vitamin D deficiency was increased with the severity of diabetic retinopathy. Univariate and multivariate logistic regression showed vitamin D deficiency was independently associated with diabetic retinopathy with a crude odds ratio of 5.69 with a p value of 0.008 and adjusted odds ratio of 16.08 with a p value of 0.002 respectively. Conclusion: Result of the study revealed that vitamin D deficiency was strongly associated with diabetic retinopathy in young people with type 1 diabetes mellitus.
文摘Despite the acceptance of physical activity （PA） being integral to a young person＇s health, children with disability often exhibit low levels of PA. In young people with cystic fibrosis （CF） the importance of exercise and daily PA is acknowledged by clinicians and their support teams, however, there is a lack of knowledge related to its prescription. CF is a recessive genetic disorder affecting the lung, pancreas and sweat glands. CF is the most common life shortening genetic disease in the Caucasian population for which there is no cure. In the UK, CF affects over 9000 people, with 4000 under 16 years of age. Only about half of the CF population can expect to live beyond 40 years of age. Besides drug therapies, rehabilitative exercise programmes form an important component of treatment and long term exercise programmes are considered positive treatment strategies, but all lack any detailed prescriptive information. Several reviews and editorials have highlighted the lack of evidence based research in PA and exercise training in young people with CF; but advocate a greater need for understanding the role of exercise in therapeutic interventions. The purpose of this review is to update the reader on the current recommendations and evidence in PA and exercise training for young people with CE These developments have extended our understanding of PA and exercise training in children and adolescents with CF, and its implementation in the management of this chronic disease.
文摘The coronavirus pandemic has affected all facets of our lives and all ages and social strata worldwide.Measures have been taken to protect against the spread of the virus,such as more rigorous hand hygiene,the use of face masks and social distancing.However,the focus has often been on young people,who have been seen as a group lacking sufficient respect for government-imposed measures.This review outlines the preventive measures that have been taken in different countries and discusses their specific impact on young people and adolescents,taking into account the developmental stage and concrete needs of this age group.It summarizes those studies that have provided information on compliance with preventive measures by young people and adolescents,concluding that although compliance levels among this age group are lower than among older adults,the general view of youths as non-compliant is not consistent with real,objective data.The review also summarizes different views regarding the possible reasons for this lower level of compliance,taking into account both social(gender and age)and personal factors(personality,empathy,prosociality,self-control,cognitive styles and motivations),and discusses the practical implications of these findings for the future.
文摘This study examined the relationship between sexual risk behavior and HIV counselling and testing uptake among young people in Nigeria. Probability sampling technique was used to obtain a sample of 10,091 respondents (ages 15 to 24 years) for the study. The multistage cluster sampling was used to select suitable young people with known probability. Data were collected throughout Nigeria between September and December 2012 from 32,543 households (rural = 22,192;urban = 10,351) using structured and semi-structured questionnaires. The data were summed using descriptive statistics. Frequencies and percentages;measures of central tendencies were used to answer the research question while nonparametric test such as chi-square was used to analyze non-normally distributed data at 0.5 level of significance. Results of data analysis indicated that sexual risk behaviors comprised three variables: sex with multiple partners, intergenerational sex (sex with partners 10 years older), and transactional sex. The results of the chi-square test of association between sex with multiple partners and HCT uptake showed that there was no statistically significant relationship between sex with multiple partners and HCT uptake among young people ages 15 to 24 years in Nigeria. It was among others recommended that sexually active young people in Nigeria should use protection against HIV infection.
文摘Since the city of Chongqing became a municipality on 14th March, 1997, the structure of Chongqing population has undergone tremendous changes. Especially the young, born after the 1980s, will play an important part in the future housing market. So it seems quite urgem to effectively satisfy the housing needs of young people. Massive research and practices indicate that the housing industrialization conserves the environment, improves quality and reduces cost of housing and is among the most effective ways to boost sustainable development of housing industry. The main objective of the paper is to discuss how to meet the growing housing demands of the young and concludes that housing with recreation, sports and other ancillary facilities will be better fit to the young to rent or to own. Furthermore, an analysis of the Chongqing housing market potential of young people＇s wish to rent or to purchase satisfactory housing demonstrates that some real estate investors may be failing to exploit serious opportunities that could arise from providing service to the young. And this case study of meeting the changing housing needs of the young may help accelerate the process of housing industrialization in Chongqing as well as providing a useful study concerning housing industry.
文摘This paper is part of a wider project being carried out by the Research Group Literary Education, Culture and Society, which has been subsidised by the Ministry of University of Spain. Our project＇s main aim is the close study of three closely interrelated phenomena, globalisation, exclusion and multiculturality, in order to determine the influences on the children and young people Literature. We intend in this paper to show the results of a first research made in a smaller corpus in order to better draw up the entire project.
文摘This study examined the relationship between HIV counselling and testing (HCT) awareness and HCT uptake among young people in Nigeria and their implications for social change. The study is a quantitative research guided by one research question and one hypothesis. The target population comprised young people in Nigeria ages 15 to 24 years because the focus of this study was to identify the factors affecting HCT uptake among young people in this age cohort. The representative sample was obtained from the updated master sample frame of rural and urban zones developed by the National Population Commission in Nigeria. This master sample frame was a national survey that comprised all 36 states in Nigeria. Probability sampling technique was used to obtain a sample of 10,091 respondents (ages 15 to 24 years) for the study. The multistage cluster sampling was used to select suitable young people with known probability. Data were collected throughout Nigeria between September and December 2012 from 32,543 households (rural = 22,192;urban = 10,351) using structured and semi-structured questionnaires. The individual questionnaires asked about household characteristics, background characteristics of the respondents. Data were analyzed by inputting them into SPSS v21.0 for analysis and then coded them for each participant. The data were summed using descriptive statistics. Frequencies and percentages;measures of central tendencies were used to answer the research question while nonparametric tests such as chi-square were used to analyze non-normally distributed data at 0.5 level of significance. The results of the chi-square test of association between HCT awareness and HCT uptake showed that there was a statistically significant relationship between HCT awareness and HCT uptake among young people ages 15 to 24 years in Nigeria, X<sup>2</sup> (1, n = 8916) = 306.66, p < 0.001. In other words, knowledge of the availability of HCT services may have influenced the possibility that the participants would use them. Among others, it was recommended that government should examine the efficacy of HCT treatments in Nigeria, along with conducting a demographic analysis of the at-risk population.
文摘What impressed you most during your stay in China？ At the invitation of Chinese leaders. I came to China in 2007. My trip gave me a chance to learn from China＇s experience educating youngergenerations. During this time. many things impressed me a lot, especial- ly the patriotism of Chinese people.
基金Science and Technology Project of Department of Science and Technology of Yunnan Province(Project No.:202102AY070001-030)The Talent Training Fund of the Joint Logistics Support Force(Project No.:20220105)Science and Technology Project of the 920^(th) Hospital of the Joint Logistics Support Force(Project No.:2020YGD11)。
文摘Objective:To investigate the differences in risk factors and prognosis between young and elderly patients with acute ST-segment elevation myocardial infarction(STEMI)so as to provide a basis for the prevention of young patients with acute STEMI.Methods:Patients initially diagnosed with STEMI in the 920"Hospital of Joint Logistic Support Force of PLA from January 1,2018 to December 31,2022 were retrospectively enrolled in this study.A total of 235 STEMI patients aged≤45 years old and 532 STEMI patients aged≥65 years old were screened.The baseline characteristics,laboratory indicators,clinical characteristics,coronary angiography,SYNTAX score and major adverse cardiovascular events(MACE)during 1-year follow-up were analyzed and compared.Results:A total of 767 STEMI patients were enrolled,including 235 in the young group and 532 in the elderly group.Among the STEM patients in the young group,224 cases were male,and smoking and drinking were common.Compared with the elderly group,the young group had shorter hospital stays and more family history of ischemic heart disease(IHD).The level of low-density lipoprotein in the young group was higher than that in the old group,while the level of high-density lipoprotein in the young group was lower than that in the old group.The level of high uric acid and homocysteine in the young group was significantly higher than that in the old group.The main cause of STEMI in the young group was fatigue,and the most common symptom was angina pectoris.Coronary angiography showed that single vessel disease was more common in the young group than in the elderly group,and the lesion in the young group was the left anterior descending artery.The SYNTAX score was significantly lower in the young group than in the elderly group according to the anatomical characteristics of coronary artery disease.In the forest plot,diabetes mellitus and a family history of IHD showed a trend of major adverse cardiovascular events(MACE)in both groups.Conclusion:Males,smokers,alcohol drinkers and family history of ischemic heart disease are more common in young patients.Common risk factors include fatigue,hyperuricemia,hyperlipidemia and so on.In addition,age itself is an independent risk factor.Management of diabetes,hyperuricemia,and homocysteine levels is essential to reduce the incidence of cardiovascular events in young patients.By controlling these factors,the incidence of young patients with acute STEMI can be effectively prevented and the corresponding prevention and treatment basis can be provided.
基金Project of Chengdu Municipal Health Commission,No.2022179.
文摘BACKGROUND Psychological problems affect economic development.However,there is a huge gap between mental health service resources and mental health service needs.Existing mental health service technology and platforms cannot meet all the diverse mental health needs of people.Smart medicine is a new medical system based online that can effectively improve the quality and efficiency of medical services and make mental health services accessible.AIM To explore the level of intelligent medical use among young and middle-aged people and its correlation with psychological factors.METHODS Convenience sampling was used to select 200 young and middle-aged patients with medical experience at the Third People's Hospital of Chengdu between January 2022 and January 2023 as the research subjects.The general condition Questionnaire,Eysenck Personality Questionnaire,Symptom Checklist-90,General Health Questionnaire,and Smart Medical Service Use Intention Questionnaire were used to collect data.Pearson’s correlation was used to analyze the correlation between the participants’willingness to use smart medical services and their personality characteristics,psychological symptoms,and mental health.RESULTS The results revealed that the mental health of young and middle-aged people was poor,and some had psycho-logical problems such as anxiety,depression,and physical discomfort.Familiarity,acceptance,and usage of smart healthcare in this population are at a medium level,and these levels correlate with psychological characteristics.Acceptance was positively correlated with E,and negatively correlated with P,anxiety,fear,anxiety/insomnia,and social dysfunction.The degree of use was negatively correlated with P,obsessive-compulsive symptoms,depression,anxiety,hostility,paranoia,and somatic symptoms.CONCLUSION The familiarity,acceptance,and usage of smart medical services among the middle-aged and young groups are related to various psychological characteristics.
基金Supported by the Joint Guidance Project of Qiqihar Science and Technology Plan in 2020,No.LHYD-202054。
文摘BACKGROUND Stroke has become one of the most serious life-threatening diseases due to its high morbidity,disability,recurrence and mortality rates.AIM To explore the intervention effect of multi-disciplinary treatment(MDT)extended nursing model on negative emotions and quality of life of young patients with post-stroke.METHODS A total of 60 young stroke patients who were hospitalized in the neurology department of our hospital from January 2020 to December 2021 were selected and randomly divided into a control group and an experimental group,with 30 patients in each group.The control group used the conventional care model and the experimental group used the MDT extended nursing model.After the inhospital and 3-mo post-discharge interventions,the differences in negative emotions and quality of life scores between the two groups were evaluated and analyzed at the time of admission,at the time of discharge and after discharge,respectively.RESULTS There are no statistically significant differences in the negative emotions scores between the two groups at admission,while there are statistically significant differences in the negative emotions scores within each group at admission and discharge,at discharge and post-discharge,and at discharge and post-discharge.In addition,the negative emotions scores were all statistically significant at discharge and after discharge when compared between the two groups.There was no statistically significant difference in quality of life scores at the time of admission between the two groups,and the difference between quality of life scores at the time of admission and discharge,at the time of discharge and post-discharge,and at the time of admission and post-discharge for each group of patients was statistically significant.CONCLUSION The MDT extended nursing mode can improve the negative emotion of patients and improve their quality of life.Therefore,it can be applied in future clinical practice and is worthy of promotion.
文摘Objective:To investigate the correlation of variables between dominant and non-dominant eyes in healthy young people.Methods:300 cases(600 eyes)of healthy young volunteers recruited in our hospital from March 2020 to February 2022were selected as the research objects.The general data of the volunteers were collected and the dominant eye,diopter,biological parameters and retinal blood flow density were detected.We compared all the test indexes of volunteers with different dominant eyes,and compared the refractive parameters,biological parameters and retinal blood flow density between the dominant and non-dominant eyes of volunteers.Results:Among the 300volunteers,62.67%(188/300)had the right eye as the dominant eye and 37.33%(112/300)had the left eye as the dominant eye.There was no significant difference in gender,BMI and equivalent spherical lens(SE)among the subjects with different dominant eyes(P>0.05).The SE and spherical diopter(S)of dominant eye were higher than that of non-dominant eye(P<0.05),but there was no significant difference between the dominant and non-dominant eye(C)(P>0.05);There was no significant difference in SE and C between dominant and non-dominant eye in volunteers with SE difference≤0.5 D and 0.51-1.25 D(P>0.05),and spherical diopter(S)of dominant eye was higher than that of non-dominant eye(P<0.05);The difference of SE was 1.26-2.00 D,>2.00 D,the SE and spherical diopter(S)of dominant eye were higher than those of non-dominant eye(P<0.05),but there was no significant difference between the dominant and non-dominant eye C(P>0.05).The levels of RA and CA in the dominant eye of 300 volunteers were lower than those in the non-dominant eye.The RA and CA levels of the dominant eye were lower than those of the non-dominant eye in volunteers with RA difference≤0.50 D,0.51-1.25 D,1.26-2.00 D,>2.00 D(P<0.05).There was no significant difference in the levels of axial length(AL),central corneal thickness(CCT),anterior chamber depth(ACD)and lens thickness(LT)between the dominant and non-dominant eyes(P>0.05).The levels of superficial retinal capillary layer(SVC),deep retinal capillary layer(DVC)and mean retinal blood flow density(RET)in dominant eyes were lower than those in non-dominant eyes.The level of AC in non-dominant eyes was higher than that in non-dominant eyes(P<0.05).Conclusion:The dominant eye of healthy young people is mostly the right eye,which has nothing to do with gender,age and BMI.Meanwhile,the biological parameters between the dominant and non-dominant eye were basically the same,the mean retinal blood flow density of the dominant eye was lower than that of the non-dominant eye,but its AC was higher than that of the non-dominant eye.
文摘BACKGROUND The incidence rate of cerebral infarction in young people is increasing day by day,the age of onset tends to be younger,and its internal pathogenesis and mechanism are very complicated,which leads to greater difficulties in treatment.Therefore,it is essential to analyze the key pathway that affects the onset of cerebral infarction in young people from the perspective of genetics.AIM To compare the differentially expressed genes in the brain tissue of young and aged rats with middle cerebral artery occlusion and to analyse their effect on the key signalling pathway involved in the development of cerebral ischaemia in young rats.METHODS The Gene Expression Omnibus 2R online analysis tool was used to analyse the differentially expressed genes in the GSE166162 dataset regarding the development of cerebral ischaemia in young and aged groups of rats.DAVID 6.8 software was further used to filter the differentially expressed genes.These genes were subjected to Gene Ontology(GO)function analysis and Kyoto Encyclopedia of Genes and Genomes(KEGG)pathway enrichment analysis to determine the key gene pathway that affects the occurrence of cerebral ischaemia in young rats.RESULTS Thirty-five differentially expressed genes(such as Igf2,Col1a2,and Sfrp1)were obtained;73 GO enrichment analysis pathways are mainly involved in biological processes such as drug response,amino acid stimulation response,blood vessel development,various signalling pathways,and enzyme regulation.They are involved in molecular functions such as drug binding,protein binding,dopamine binding,metal ion binding,and dopamine neurotransmitter receptor activity.KEGG pathway enrichment analysis showed a significantly enriched pathway:The cyclic adenosine monophosphate(c-AMP)signalling pathway.CONCLUSION The c-AMP signalling pathway might be the key pathway in the intervention of cerebral infarction in young people.
基金supported by the Philosophy and Social Science Planning Project of Henan Province(2020BSH015).
文摘This study investigates mental health literacy among young and middle-aged urban and rural residents and the differences in mental health literacy,perceived social support and subjective well-being.From January to February 2022,620 participants(320 rural and 300 urban residents)from three provinces of China were selected by con-venience sampling.A general data questionnaire,mental health literacy scale,perceived social support scale and subjective well-being scale were administered.The mental health literacy scores of urban residents were 3.34±0.57 and those of rural residents were 2.73±0.79.The results of multiple regression analysis showed that the mental health literacy scores of rural residents were more significant than those of urban residents in terms of sex and age,while urban residents’mental health literacy scores were more significant than those of rural resi-dents in terms of monthly income.Mental health literacy,perceived social support and subjective well-being of young and middle-aged urban and rural residents were all positively correlated(P<0.01).While the level of mental health literacy is better among urban residents than rural residents,perceived social support plays a partial mediating role between mental health literacy and subjective well-being of both urban and rural residents,and should be the focus of researchers seeking to improve the level of well-being of residents.
文摘Sexually transmitted diseases （STDs） are among the first ten causes of unpleasant diseases in young adult males in developing countries and the second major cause of unpleasant diseases in young adult women. Adolescents and young adults （15-24 years old） make up only 25% of the sexually active population, but represent almost 50% of all new acquired STDs. In general, STDs are epidemics and present an enormous health and economic consequences. An adequate screening for STDs should be done on a routine basis in every part of the world. Many STDs are asymptomatic and therefore can difficult to control. The purpose of reporting of STDs is to ensure that persons who are infected will be quickly diagnosed and appropriately treated to control the spread of infection and also so that partners are notified, tested and appropriately treated. It is estimated that reported cases of STDs represent only 50%-80% of reportable STD infections in the United States, reflecting limited screening and low disease reporting. High-risk sexual behavior is a highly contributive factor of this process as it often leads to teenage pregnancies and HIV/AIDS. One possible explanation for this behavior is that people do not have enough information about the transmission of STDs or ignore the precautions required for safe sex. Approximately 60% of new HIV infections worldwide occur in young people. The frequency of high-risk behaviors among youths may also be influenced by opportunity to engage in them, particularly the amount of time that they are unsupervised by adults. However, in diagnosing and treating these patients, we can effectively prevent the spread of HIV/AIDS. Individuals infected with STDs are 5-10 times more likely than uninfected individuals to acquire or transmit HIV through sexual contact. The breaking of the genital tract lining or skin creates a portal of entry for HIV and, hence, HIV-infected individuals with other STDs are more likely to shed HIV in their genital secretions. To date, the condom is the most effective method available for males for protection against STDs. It is important to control STDs, and prevention can be the key of this process. Prevention can be achieved through education of the population, identification of symptomatic and asymptomatic people, and effective diagnosis and treatment of these patients and their partners.
文摘BACKGROUND:Coffee is commonly consumed among young people in China. However,consumers are rarely aware of physically adverse effects as a result of excessive consumption of caffeine.DATA SOURCES:A literature search using multiple databases was performed for articles published with concentration on meta-analyses,systematic reviews,and randomized controlled trials.RESULTS:Excess coffee consumption is also a risk of primary cardiac arrest especially in young people. Treatment modalities include activated charcoals,beta-blockers,vasopressin and hemodialysis when necessary.CONCLUSION:Coffee consumers should be advised not to routinely take more than moderate coffee.
文摘This project was supported by the Department of Antidrug Policies of the Italian Government＇s Presidency Council and it was undertaken by the Forensic Toxicology Division of the University of Florence, in order to identify the age of onset of abuse of alcohol, caffeine and nicotine, through a scientific approach. The study involved 874 volunteer students aged between 13 and 16 years donating a small lock of their hair. The toxicological researches were performed with gas chromatography-mass spectrometer and liquid chromatography-tandem mass spectrometer instrumentations, on 50 mg of hair （3/4 cm proximal）, detecting： FAEE （fatty acids ethyl esters） and EtG （ethyl glucuronide） as markers of alcohol intake; nicotine and cotinine; caffeine. A self-reported questionnaire was also submitted. The main results showed that 17.6% drinks alcohol （3% is a ＂heavy drinkers＂）, 43.5% ingests more than an espresso/day （21.4% more than 2 espresso/day） and 24.3% is an active smokers （17.0% of ＂heavy smokers＂）. This study depicted a worrisome picture due to the early contact of the adolescents with these substance; moreover it demonstrated that the knowledge about this phenomenon by means of scientific evidences （not only by self-reported questionnaires）, is the only basis for its comprehension and for planning effective prevention strategies.
文摘The Paediatric Observation Priority Score (POPS) is a bespoke assessment tool for use in Paediatric Emergency Departments incorporating traditional physiological parameters alongside more subjective observational criteria. Initial performance characteristics of POPS were analysed in a convenience sample of 936 presentations to ED. Triage on the basis of gut instinct parameters identified an additional 261 patients deemed of lowest acuity compared to analysis by physiology scores. Resource consumption increased with increasing acuity on presentation. POPS shows promise in assisting in the assessment process of children presenting to Emergency Departments. Inclusion of subjective triage criteria helps contextualise the physiological parameter scoring by using the experience of staff conducting triage. Initial interpretation of presenting physiology gives a more informed assessment of initial acuity, and thus is better able to identify a child who can be safely managed in the community. The system also allows for rapid detection of those most unwell.
基金Our sincere thanks to the European Union of the project teams of Enabling University Peace Education in British Council and all those who provided unconditional support.We would like to thank Dr.Muatsim Ibrahim Malik as supervisor and Dr.Afag Mohammed Sadig as co-supervisor for their support,suggestions and comments that helped us improve the same.We are also grateful to Ustaz Bashir Ibrahim for his help and support in data collection.A special mention and grateful thanks to Gadarif community specifically youth for their cooperation in data collection,which has contributed to our research experience.
文摘This study in Gadarif State,Sudan,analyzes the crucial role of youth in conflict resolution and peace building efforts amidst the ongoing crisis.Findings reveal that youth,facing economic,environmental,and security challenges,actively engage in peacemaking through initiatives,emergency rooms,and cultural programs,contributing to social cohesion and combatting hate speech.Despite their willingness to build peace,they encounter obstacles like the lack of training programs,limited support,and marginalization in policy-making processes.Recommendations emphasize the necessity of empowering youth through training programs,enhancing government support,and addressing negative perceptions from older generations towards youth contributions.Conclusively,prioritizing youth issues and fostering their participation in peace building initiatives are essential for sustainable peace and social harmony in Gadarif State.
