Parasitic disease is one of the most serious diseases in humans and animals. Animal antiparasitic drugs are mainly used to kill, expel and prevent animal parasites, and they are divided into anthelmintics, antiprotozo...Parasitic disease is one of the most serious diseases in humans and animals. Animal antiparasitic drugs are mainly used to kill, expel and prevent animal parasites, and they are divided into anthelmintics, antiprotozoals, insecticides, and so on. Animal antiparasitic drugs play an important role in the prevention and control of animal parasitic diseases, healthy development of animal husbandry and security of public health. In recent years, as people pay more attention paid to parasitic diseases, the research and development of antiparasitic drugs have made great progresses. Mastering the research and application progresses of antiparasitic drugs is of great significance to clinical medication and basic research. This paper reviews the history, current situation, the latest progresses and future development directions of research and application of antiparasitic drugs.展开更多
Macrolide antibiotics have been widely used in clinic due to their good antibacterial effects and high safety, but the drug-resistant bacteria appear constantly. To solve the problem of drug resistance in pathogens, s...Macrolide antibiotics have been widely used in clinic due to their good antibacterial effects and high safety, but the drug-resistant bacteria appear constantly. To solve the problem of drug resistance in pathogens, scholars obtain the third generation of macrolide antibiotics, ketolide antibiotics, which are developed by modifying the structure of macrolide antibiotics, thereby efficiently solving the problem. Ketolide antibiotics are a type of erythromycin derivatives with macrolide structure, and the typical drugs mainly include telithromycin, cethromycin and solithromycin, etc . This paper briefly introduced the recent progress of ketolide antibiotics, with an attempt to provide help to the research and development of new macrolide antibiotics.展开更多
基金Supported by Earmarked Fund for China Agriculture Research System(CAR-38)Twelfth Five-Year National Key Technology Research and Development Program(2015BAD1101)~~
文摘Parasitic disease is one of the most serious diseases in humans and animals. Animal antiparasitic drugs are mainly used to kill, expel and prevent animal parasites, and they are divided into anthelmintics, antiprotozoals, insecticides, and so on. Animal antiparasitic drugs play an important role in the prevention and control of animal parasitic diseases, healthy development of animal husbandry and security of public health. In recent years, as people pay more attention paid to parasitic diseases, the research and development of antiparasitic drugs have made great progresses. Mastering the research and application progresses of antiparasitic drugs is of great significance to clinical medication and basic research. This paper reviews the history, current situation, the latest progresses and future development directions of research and application of antiparasitic drugs.
基金Supported by National Sci-tech Support Plant during Twelfth Five-Year Plan(2015BAD1101)Earmarked Fund for China Agriculture Research System(CAR-38)~~
文摘Macrolide antibiotics have been widely used in clinic due to their good antibacterial effects and high safety, but the drug-resistant bacteria appear constantly. To solve the problem of drug resistance in pathogens, scholars obtain the third generation of macrolide antibiotics, ketolide antibiotics, which are developed by modifying the structure of macrolide antibiotics, thereby efficiently solving the problem. Ketolide antibiotics are a type of erythromycin derivatives with macrolide structure, and the typical drugs mainly include telithromycin, cethromycin and solithromycin, etc . This paper briefly introduced the recent progress of ketolide antibiotics, with an attempt to provide help to the research and development of new macrolide antibiotics.
