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针刺提高大鼠学习记忆功能与其抗氧化作用的关系(英文) 被引量:9
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作者 欧阳颀 李忠仁 +2 位作者 穆艳云 马骋 沈梅红 《中国临床康复》 CSCD 2003年第25期3450-3452,共3页
目的:研究针刺对大鼠学习记忆的影响,分析针刺影响大鼠学习记忆与其影响脑内自由基反应的关系。方法:筛选体质量和灵活性等较一致健康大鼠40只,按随机数字表随机分成4组,每组10只。其中针刺组用30#美容针于实验开始之日起针刺固定于自... 目的:研究针刺对大鼠学习记忆的影响,分析针刺影响大鼠学习记忆与其影响脑内自由基反应的关系。方法:筛选体质量和灵活性等较一致健康大鼠40只,按随机数字表随机分成4组,每组10只。其中针刺组用30#美容针于实验开始之日起针刺固定于自制大鼠固定架上的大鼠肾俞、百会穴。百会向前平刺3~5mm,肾俞向内斜刺5mm,接G6805电针仪刺激10min,连续波,频率为3Hz,以大鼠肢体抖动为刺激强度标准,1次/d,连续7d;尼莫组灌服尼莫地平混悬液10mL/kg,1次/d,连续7d;模型组和空白组自实验第1天起,与针刺组同样方式固定,10min/次,1次/d,连续7d。采用水迷宫测试正常大鼠和亚硝酸钠所致痴呆大鼠的学习记忆能力,同时测定被试大鼠脑内过氧化脂质(LPO)含量和超氧化歧化酶(SOD)活性。结果:在第5天训练末,针刺组在(9.3±2.6)s即可登陆,而空白组在(45.5±7.6)s才能成功登陆,说明针刺能提高正常大鼠的学习记忆能力;造模后模型组登陆时间持续居高,而针刺组登陆时间逐渐缩短,较之模型组差异有显著性意义(t=2.982,P<0.05)。此外,在第12天的末次测试中,模型组错误次数为(5.71±1.37)次,针刺组分别为(0.73±0.25)次,均较模型组减少,差异具有非常显著性意义(t=3.576,P<0.01),提示针刺能拮抗亚硝酸钠对大鼠空间识别记忆巩固的破坏;针刺组大鼠? 展开更多
关键词 针刺 学习记忆能力 自由基 过氧化脂质 超氧化物歧化酶
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肖少卿“透穴针法”举要 被引量:3
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作者 欧阳八四 高洁 肖少卿 《中医杂志》 CSCD 北大核心 1997年第9期534-535,共2页
肖少卿教授从事针灸教学、科研、临床工作数十载。笔者受业于肖老,肖老临床常用“透穴针法”治疗。透穴针法为采用不同的方向、角度和深度以同一针作用于两个或两个以上穴位的针刺方法。其在《内经》中即有其雏形。随着医学的发展,后世... 肖少卿教授从事针灸教学、科研、临床工作数十载。笔者受业于肖老,肖老临床常用“透穴针法”治疗。透穴针法为采用不同的方向、角度和深度以同一针作用于两个或两个以上穴位的针刺方法。其在《内经》中即有其雏形。随着医学的发展,后世发展并完善了这种刺法。肖老在临床中不断探索。 展开更多
关键词 透针 名医经验 肖少卿 腰扭伤
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神经损伤对骨代谢影响的实验研究 被引量:5
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作者 高润 阮德明 《中国实用神经疾病杂志》 2006年第6期55-57,共3页
目的通过对90只大鼠神经损伤后,IGF-1(胰岛素样生长因子-1)和NGF(神经生长因子)对骨代谢变化的研究,探讨神经系统影响骨代谢的可能机制。方法90只实验大鼠随机分为中枢损伤组(脊髓横断)30只,周围神经损伤组(坐骨神经和股神经离断)30只,... 目的通过对90只大鼠神经损伤后,IGF-1(胰岛素样生长因子-1)和NGF(神经生长因子)对骨代谢变化的研究,探讨神经系统影响骨代谢的可能机制。方法90只实验大鼠随机分为中枢损伤组(脊髓横断)30只,周围神经损伤组(坐骨神经和股神经离断)30只,正常对照组30只。每组又根据7、21、42d不同时间段分为3个亚组,每组10只。结果神经损伤组后不同时间段血钙、血碱性磷酸酶(ALP)、尿钙(Ca)和尿肌苷(Cr)及Ca/Cr均发生明显改变,骨IGF-1和NGF含量与神经损伤明显相关,且呈程度依赖性改变,特别是NGF含量神经损伤组与正常组比较有显著性差异,并呈现动态的“双相增高”现象,其中枢损伤组变化更为显著。结论神经系统对骨组织内环境调节是多层次、多元和复杂的,IGF-1和NGF作为骨代谢调节中重要的神经肽及营养因子,在骨吸收和骨形成耦联机制中发挥着极其重要的作用,通过课题研究证明,神经系统对骨代谢调节具有重要作用,并为今后进一步建立“神经-内分泌-骨的轴线调节理论”和制定骨相关疾病的治疗与康复措施奠定基础。 展开更多
关键词 骨代谢 神经损伤 IGF-1 NGF
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艾灸干预血管内皮细胞损伤作用机制研究进展 被引量:7
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作者 强晟 朱德淳 张建斌 《山西中医》 2021年第3期58-60,共3页
艾灸干预血管内皮功能的启动机制尚未明确。搜集整理近年来相关文献,总结艾灸干预血管内皮细胞损伤的机制,主要涉及抗氧化应激、抗炎症反应、调节Hcy浓度、调节ox-LDL含量、调节多种血管活性物质水平等方面,为临床进一步优化治疗方案、... 艾灸干预血管内皮功能的启动机制尚未明确。搜集整理近年来相关文献,总结艾灸干预血管内皮细胞损伤的机制,主要涉及抗氧化应激、抗炎症反应、调节Hcy浓度、调节ox-LDL含量、调节多种血管活性物质水平等方面,为临床进一步优化治疗方案、提高疗效提供理论依据。 展开更多
关键词 艾灸 血管内皮细胞 作用机制 综述
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软组织损伤超声成像的康复临床应用意义 被引量:1
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作者 朱毅 励建安 朱黎婷 《中华物理医学与康复杂志》 CAS CSCD 北大核心 2011年第11期873-875,共3页
超声诊断学始于20世纪,最早是由美国海军医学研究所的Ludwig在临床开展应用的。虽然超声检查应用于软组织成像只有20多年,但目前其已在软组织疾病的诊断中发挥着难以取代的作用。随着便携式超声仪的问世,为软组织损伤的超声检查在临... 超声诊断学始于20世纪,最早是由美国海军医学研究所的Ludwig在临床开展应用的。虽然超声检查应用于软组织成像只有20多年,但目前其已在软组织疾病的诊断中发挥着难以取代的作用。随着便携式超声仪的问世,为软组织损伤的超声检查在临床的应用提供了更多的便利。 展开更多
关键词 软组织损伤 临床 超声成像 海军医学研究所 超声诊断学 用意 康复 超声检查
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无步行能力脑卒中偏瘫患者踏车有氧训练有效性的初步研究 被引量:5
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作者 王尊 范宏娟 +5 位作者 陆晓 王翔 朱晓军 顾一煌 王磊 王彤 《中华物理医学与康复杂志》 CAS CSCD 北大核心 2011年第12期924-927,共4页
目的研究无辅助步行和独立步行能力的脑卒中偏瘫患者进行低强度踏车有氧训练的有效性。方法将无辅助步行和独立步行能力的脑卒中偏瘫患者30例分为对照组和有氧训练组。2组患者均接受常规康复治疗,有氧训练组患者在常规康复治疗的基础... 目的研究无辅助步行和独立步行能力的脑卒中偏瘫患者进行低强度踏车有氧训练的有效性。方法将无辅助步行和独立步行能力的脑卒中偏瘫患者30例分为对照组和有氧训练组。2组患者均接受常规康复治疗,有氧训练组患者在常规康复治疗的基础上进行每周3次、每次30min、共6周的低强度踏车有氧训练。2组患者总康复治疗时程和时间均相等。治疗前、后2组患者均采用Fugle-Meyer运动功能评分法(FMA)和Rivermead运动指数评定肢体功能,运用Barthel指数(BI)评定日常生活活动(ADL)能力,并进行运动试验终止心率、耐受时间及实验室检查[空腹血糖、血胰岛素、血脂、血胆固醇、高敏C反应蛋白、口服葡萄糖耐量试验(OGTT)2h血糖和胰岛素等,并计算稳态模型胰岛素抵抗指数(HOMA—IR)]。结果24例患者完成观察程序(每组12例)。2组患者治疗前、后肢体运动功能、运动试验耐受时间、空腹胰岛素、OGTT2h血糖、HOMA-IR等指标明显改善(P〈0.05),治疗后2组间FMA、Rivermead指数、BI、运动试验耐受时间、空腹胰岛素及OGTT2h血糖等差异均有统计学意义(P〈0.05)。结论低强度踏车有氧训练可以有效应用于无步行能力的脑卒中偏瘫患者。 展开更多
关键词 脑卒中 有氧训练 有效性
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Case of post-stroke depression 被引量:2
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作者 Facai LIN 《World Journal of Acupuncture-Moxibustion》 CSCD 2018年第1期61-62,I0009,共3页
By adopting the psychosomatic therapy, the author treated 1 case of post-stroke depression through applying traditional acupuncture, acupoint injection combined with TCM five-element music therapy. After treatment, th... By adopting the psychosomatic therapy, the author treated 1 case of post-stroke depression through applying traditional acupuncture, acupoint injection combined with TCM five-element music therapy. After treatment, the neurological functions of the patient obviously recovered, Hamilton Depression(HAMD)Scale(17 items) score reduced, the levels of tumor necrosis factor and hypersensitive C-reactive protein both declined, and all the indicators were improved significantly, indicating that the curative effect of acupuncture combined with TCM five-element music therapy on this PSD patient was significant, and this treatment method was worthy of further exploration. 展开更多
关键词 STROKE Post-stroke depression ACUPUNCTURE Five-element music Music therapy
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Mechanism of the acupoints of the governor vessel in treatment of post-stroke depression on the base of the specificity of meridian points 被引量:1
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作者 Linxia QIAN Yueting JIANG Facai LIN 《World Journal of Acupuncture-Moxibustion》 CSCD 2019年第3期244-248,共5页
Focusing on the effect specificity of meridian points along the running course of meridian,by taking the treatment of post-stroke depression(PSD)with the acupoints of the governor vessel as an example,the correlation ... Focusing on the effect specificity of meridian points along the running course of meridian,by taking the treatment of post-stroke depression(PSD)with the acupoints of the governor vessel as an example,the correlation between meridian points and disease was explored.The specific regulatory effect of governor vessel,Baihui(百会GV20)and Shenting(神庭GV24)in physiology and pathology in PSD and the material basis of the specificity effect were analyzed.Finally,the specific relationship between the acupoints of the governor vessel and PSD was explained. 展开更多
关键词 SPECIFICITY of MERIDIAN POINTS POST-STROKE depression Governor vessel Baihui(百会GV20) Shenting(神庭GV24)
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Wrist–ankle acupuncture combined with pinching along the spine for children allergic rhinitis: A randomized controlled trial 被引量:1
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作者 Yu Liu Yi-Huang Gu Ying Xiong 《World Journal of Acupuncture-Moxibustion》 CSCD 2019年第4期259-263,共5页
Objective:To investigate the clinical effect of wrist–ankle acupuncture combined with pinching along the spine on allergic rhinitis(AR)in children.Methods:A total of 65 children with AR were collected from February 2... Objective:To investigate the clinical effect of wrist–ankle acupuncture combined with pinching along the spine on allergic rhinitis(AR)in children.Methods:A total of 65 children with AR were collected from February 2017 through to December 2018 and they were randomly divided into a combined treatment group with wrist–ankle acupuncture,pinching along the spine and western medication(combined treatment group,32 cases)and a western medication group(33 cases).In the western medication group,loratadine was prescribed for oral administration.In the combined treatment group,on the base of the medication as the western medication group,the wrist–ankle acupuncture was adopted in combination with pinching along the spine.Before and after treatment,the symptoms and physical signs were scored and the clinical effect was observed in the children of the two groups.Results:After the treatment and in the follow-up,the scores of the symptoms and physical signs in the combined treatment group were lower than those of the western medication group,indicating a statistical significance(all P<0.05).The total effective rate was 93.7%in the combined treatment group,which was higher than 63.63%in the western medication group,indicating a statistical significance(P<0.05).Conclusion:The combined treatment of wrist–ankle acupuncture combined with pinching along the spine and loratadine effectively relieves the clinical symptoms and the physical signs in AR children.The clinical effect of this combined treatment is better than the simple use of loratadine. 展开更多
关键词 Wrist–ankle acupuncture Pinching along the spine Children Allergic rhinitis Randomized controlled trial(RCT)
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Experimental research progress on the effect of moxibustion on liver and its influence factors 被引量:1
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作者 Qian XU Ping-ping TANG +3 位作者 Chuan-yang JIN Li-yuan LIU Ru-lin YE Jian-bin ZHANG 《World Journal of Acupuncture-Moxibustion》 CSCD 2020年第3期217-222,共6页
Through retrieving the relevant experimental researches from Pubmed,CNKI,Wanfang and VIP databases,it is discovered that the effects of moxibustion on liver are mainly reflected in the following three aspects,namely,m... Through retrieving the relevant experimental researches from Pubmed,CNKI,Wanfang and VIP databases,it is discovered that the effects of moxibustion on liver are mainly reflected in the following three aspects,namely,maintaining the normal functions of liver,promoting the repair of liver injury and delaying liver aging.By further analysis and in view of experiments,the factors influencing these effects may include stimulation site,stimulation intensity and heat source.The effects of moxibustion on liver and its influencing factors are explored and discovered in the perspective of experimental researches and these discoveries have been verified in clinical practice correspondingly.Based on the current study situation,moxibustion therapy is still limited in clinical studies on liver disorders as compared with the experimental researches.Hence,the deep exploration of moxibustion on its specific biological effect and mechanism and the excavation of moxibustion on its clinical application are likely to be the coming emphasis of the basic research and clinical practice for moxibustion. 展开更多
关键词 MOXIBUSTION Effect of moxibustion on liver Influencing factors Experimental research progress
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Globus hystericus co-treated with acupuncture and five-element music therapy
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作者 Lin-xia QIAN Fa-cai LIN 《World Journal of Acupuncture-Moxibustion》 CSCD 2019年第1期80-82,共3页
In order to mutually regulate mental and physical conditions, the authors adopted acupuncture in combination with five-element music therapy of traditional Chinese medicine(TCM) for 1 case of globus hystericus. Bǎih... In order to mutually regulate mental and physical conditions, the authors adopted acupuncture in combination with five-element music therapy of traditional Chinese medicine(TCM) for 1 case of globus hystericus. Bǎihui(百会 GV 20),Hégǔ(合谷 LI 4)、Zhōngwǎn(中脘 CV 12).Qìhǎi(气海 CV 6) et al. were needled once every other day and music of Zhi tone was played for the patient. A further study is needed for the application of this therapeutic method. 展开更多
关键词 ACUPUNCTURE Five-element MUSIC MUSIC THERAPY EMOTION GLOBUS hystericus
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