1文献来源Petrelli F,Sgroi G,Sarti E,et al.Increasing the interval between neoadjuvant chemoradiotherapy and surgery in rectal cancer:A meta-analysis of published studies[J].Ann Surg,2016,263(3):458-464.2证据水平1b。3...1文献来源Petrelli F,Sgroi G,Sarti E,et al.Increasing the interval between neoadjuvant chemoradiotherapy and surgery in rectal cancer:A meta-analysis of published studies[J].Ann Surg,2016,263(3):458-464.2证据水平1b。3背景·现有的局部进展期直肠癌(cT3-4/cN+)的治疗方案为新辅助放化疗(chemoradiotherapy,CRT)+全直肠系膜切除术(total mesorectal excision,TME)。·局部进展期直肠癌可以通过术前治疗获得病理降期,手术可以达到R0切除,并增加局部控制率、改善临床结局。·CRT结束后等待手术的时间超过经典的6~8周能否使患者获益仍未明确。展开更多
文摘1文献来源Petrelli F,Sgroi G,Sarti E,et al.Increasing the interval between neoadjuvant chemoradiotherapy and surgery in rectal cancer:A meta-analysis of published studies[J].Ann Surg,2016,263(3):458-464.2证据水平1b。3背景·现有的局部进展期直肠癌(cT3-4/cN+)的治疗方案为新辅助放化疗(chemoradiotherapy,CRT)+全直肠系膜切除术(total mesorectal excision,TME)。·局部进展期直肠癌可以通过术前治疗获得病理降期,手术可以达到R0切除,并增加局部控制率、改善临床结局。·CRT结束后等待手术的时间超过经典的6~8周能否使患者获益仍未明确。
