无创产前检测(Non-Invasive Prenatal Testing, NIPT)自临床应用以来,因其方便快捷、无需侵入的特点于全球迅速开展。胎儿游离DNA浓度(Fetal Fraction, FF)是NIPT的质控参数,同时也可作为预测不良妊娠结局的重要指标。本文旨在分析总结F...无创产前检测(Non-Invasive Prenatal Testing, NIPT)自临床应用以来,因其方便快捷、无需侵入的特点于全球迅速开展。胎儿游离DNA浓度(Fetal Fraction, FF)是NIPT的质控参数,同时也可作为预测不良妊娠结局的重要指标。本文旨在分析总结FF的影响因素及与胎盘相关性不良妊娠结局的关系,以期发挥FF在临床应用中的价值。Non-invasive prenatal testing (NIPT) has been rapidly developed worldwide due to its characteristics, including convenience and non-invasive. Fetal fraction (FF) is a parameter of sample quality control for NIPT and can also be used as an important indicator for predicting adverse pregnancy outcomes. This article aims to analyze and summarize the influencing factors of FF and the relationship between FF with placenta-related adverse pregnancy outcomes, in order to exert the value of FF in clinical application.展开更多
文摘无创产前检测(Non-Invasive Prenatal Testing, NIPT)自临床应用以来,因其方便快捷、无需侵入的特点于全球迅速开展。胎儿游离DNA浓度(Fetal Fraction, FF)是NIPT的质控参数,同时也可作为预测不良妊娠结局的重要指标。本文旨在分析总结FF的影响因素及与胎盘相关性不良妊娠结局的关系,以期发挥FF在临床应用中的价值。Non-invasive prenatal testing (NIPT) has been rapidly developed worldwide due to its characteristics, including convenience and non-invasive. Fetal fraction (FF) is a parameter of sample quality control for NIPT and can also be used as an important indicator for predicting adverse pregnancy outcomes. This article aims to analyze and summarize the influencing factors of FF and the relationship between FF with placenta-related adverse pregnancy outcomes, in order to exert the value of FF in clinical application.
