随着技术的发展,纳米超声造影剂的研究越来越多,除了常规的微泡结构纳米超声造影剂,还出现了许多新型的纳米超声造影剂,这些纳米超声造影剂经过修饰或负载药物被赋予了疾病治疗能力。本文针对这些纳米超声造影剂各自的优缺点和实现临床...随着技术的发展,纳米超声造影剂的研究越来越多,除了常规的微泡结构纳米超声造影剂,还出现了许多新型的纳米超声造影剂,这些纳米超声造影剂经过修饰或负载药物被赋予了疾病治疗能力。本文针对这些纳米超声造影剂各自的优缺点和实现临床转化中遇到的困难进行综述。With the development of technology, nanosized ultrasound contrast agents are increasingly being investigated. In addition to conventional microbubble-structured nanosized ultrasound contrast agents, a number of novel nanosized ultrasound contrast agents have emerged that have been modified or loaded with drugs to be endowed with disease-treating capabilities. This paper provides a review of the advantages and disadvantages of each of these nanosized ultrasound contrast agents and the difficulties encountered in achieving clinical translation.展开更多
文摘随着技术的发展,纳米超声造影剂的研究越来越多,除了常规的微泡结构纳米超声造影剂,还出现了许多新型的纳米超声造影剂,这些纳米超声造影剂经过修饰或负载药物被赋予了疾病治疗能力。本文针对这些纳米超声造影剂各自的优缺点和实现临床转化中遇到的困难进行综述。With the development of technology, nanosized ultrasound contrast agents are increasingly being investigated. In addition to conventional microbubble-structured nanosized ultrasound contrast agents, a number of novel nanosized ultrasound contrast agents have emerged that have been modified or loaded with drugs to be endowed with disease-treating capabilities. This paper provides a review of the advantages and disadvantages of each of these nanosized ultrasound contrast agents and the difficulties encountered in achieving clinical translation.