AIM: To understand the relationship between the migration of NSC and the expression of bFGF after permanent cerebral ischemia. METHODS: Choosing rats with permanent cerebral ischemia as models and adopting immunohisto...AIM: To understand the relationship between the migration of NSC and the expression of bFGF after permanent cerebral ischemia. METHODS: Choosing rats with permanent cerebral ischemia as models and adopting immunohistochemical staining to observe the migration of NSC in the state of cerebral ischemia and the expression of bFGF protein. RESULTS: There was a migration pattern with time space accordance between NSCs and bFGF + cells which migrated from SEZ towards ischemic cerebral tissue along ventral side of corpus callosum, and the intense bFGF protein expression in the corpus callosum after ischemia. Many bFGF + cells were found within and near the ischemic tissue after long time ischemia. CONCLUSION: The migration of NSCs from SEZ to ischemic area might need the sustenance of bFGF protein.展开更多
文摘AIM: To understand the relationship between the migration of NSC and the expression of bFGF after permanent cerebral ischemia. METHODS: Choosing rats with permanent cerebral ischemia as models and adopting immunohistochemical staining to observe the migration of NSC in the state of cerebral ischemia and the expression of bFGF protein. RESULTS: There was a migration pattern with time space accordance between NSCs and bFGF + cells which migrated from SEZ towards ischemic cerebral tissue along ventral side of corpus callosum, and the intense bFGF protein expression in the corpus callosum after ischemia. Many bFGF + cells were found within and near the ischemic tissue after long time ischemia. CONCLUSION: The migration of NSCs from SEZ to ischemic area might need the sustenance of bFGF protein.
