目的探讨乳腺肿瘤的多参数MRI特征(T_(2)-WI、ADC值和DCE)以及乳腺密度和背景实质增强(BPE)特征在不同乳腺癌(BC)分子亚型中的差异,以期为临床诊断提供重要参考。方法本研究为回顾性研究,纳入344例患者。所有患者均接受了多参数乳房MRI(...目的探讨乳腺肿瘤的多参数MRI特征(T_(2)-WI、ADC值和DCE)以及乳腺密度和背景实质增强(BPE)特征在不同乳腺癌(BC)分子亚型中的差异,以期为临床诊断提供重要参考。方法本研究为回顾性研究,纳入344例患者。所有患者均接受了多参数乳房MRI(T_(2)WI、ADC和DCE序列),并根据最新的BIRADS提取特征,使用ROI之间的类内系数(ICC)来评估读者间协议。结果研究人群分为:luminal A 89例(26%),luminal B HER2阳性39例(11.5%),luminal B HER2阴性168例(48.5%),三阴性(TNBC)41例(12%),HER2富集7例(2%)。Luminal内A肿瘤与特殊的组织学类型、最小的肿瘤大小和持续的动力学曲线相关(P均<0.05)。Luminal B HER2阴性肿瘤与最低ADC值相关(0.77×10^(-3)mm^(2)/s^(2)),其预测BC分子亚型的准确性为0.583。TNBC与不对称和中度/显著BPE,圆形/椭圆形肿块,边缘受限和边缘增强相关(P均<0.05)。HER2富集的BC与最大肿瘤大小相关(平均37.28mm,p值=0.02)。结论BC分子亚型与T_(2)WI、ADC和DCE MRI特征相关,ADC有助于预测luminal B HER2阴性病例。展开更多
肠梗阻是指各种原因引起的肠道内容物不能顺利通过肠道,是临床中常见疾病,其可分为:机械性肠梗阻、动力性肠梗阻、血运性肠梗阻。在机械性肠梗阻中,除了肿瘤、肠壁扭转、肠道粘连、粪石嵌顿、蛔虫成团等常见病因外,还有一个相对罕见的病...肠梗阻是指各种原因引起的肠道内容物不能顺利通过肠道,是临床中常见疾病,其可分为:机械性肠梗阻、动力性肠梗阻、血运性肠梗阻。在机械性肠梗阻中,除了肿瘤、肠壁扭转、肠道粘连、粪石嵌顿、蛔虫成团等常见病因外,还有一个相对罕见的病因,即发育异常导致本应退化的结构长期存在刺激肠道引发局部炎症及狭窄。脐部肠道索带是由卵黄管发育异常所形成的,其存在可引起肠梗阻等疾病,通过常规检查很难明确病因,多在术中探查时明确。因此结合临床病例探讨其发病机制及诊疗措施对于该疾病的研究有着重大意义。本案报道1例脐部肠道索带引发肠梗阻的病例。现将整个治疗过程阐述如下。Intestinal obstruction refers to the failure of intestinal contents to pass through the intestines for various causes, and is a common disease in the clinic, which can be divided into: mechanical intestinal obstruction, dynamic intestinal obstruction and haemodynamic intestinal obstruction. In mechanical intestinal obstruction, in addition to tumours, intestinal wall torsion, intestinal adhesions, faecal impaction, roundworm formation and other common causes, there is also a relatively rare cause, that is, developmental anomalies lead to long-term presence of degenerative structures that irritate the intestinal tract and cause local inflammation and stenosis. The umbilical intestinal cord is formed by the abnormal development of the vitelline duct, and its presence can cause intestinal obstruction and other diseases. It is difficult to clarify the etiology of the disease through routine examination, and it is mostly clarified during intraoperative exploration. Therefore, exploring its pathogenesis and diagnostic and therapeutic measures in conjunction with clinical cases is of great significance to the study of this disease. This case reports a case of intestinal obstruction caused by umbilical intestinal cord. The whole treatment process is described as follows.展开更多
文摘目的探讨乳腺肿瘤的多参数MRI特征(T_(2)-WI、ADC值和DCE)以及乳腺密度和背景实质增强(BPE)特征在不同乳腺癌(BC)分子亚型中的差异,以期为临床诊断提供重要参考。方法本研究为回顾性研究,纳入344例患者。所有患者均接受了多参数乳房MRI(T_(2)WI、ADC和DCE序列),并根据最新的BIRADS提取特征,使用ROI之间的类内系数(ICC)来评估读者间协议。结果研究人群分为:luminal A 89例(26%),luminal B HER2阳性39例(11.5%),luminal B HER2阴性168例(48.5%),三阴性(TNBC)41例(12%),HER2富集7例(2%)。Luminal内A肿瘤与特殊的组织学类型、最小的肿瘤大小和持续的动力学曲线相关(P均<0.05)。Luminal B HER2阴性肿瘤与最低ADC值相关(0.77×10^(-3)mm^(2)/s^(2)),其预测BC分子亚型的准确性为0.583。TNBC与不对称和中度/显著BPE,圆形/椭圆形肿块,边缘受限和边缘增强相关(P均<0.05)。HER2富集的BC与最大肿瘤大小相关(平均37.28mm,p值=0.02)。结论BC分子亚型与T_(2)WI、ADC和DCE MRI特征相关,ADC有助于预测luminal B HER2阴性病例。
文摘肠梗阻是指各种原因引起的肠道内容物不能顺利通过肠道,是临床中常见疾病,其可分为:机械性肠梗阻、动力性肠梗阻、血运性肠梗阻。在机械性肠梗阻中,除了肿瘤、肠壁扭转、肠道粘连、粪石嵌顿、蛔虫成团等常见病因外,还有一个相对罕见的病因,即发育异常导致本应退化的结构长期存在刺激肠道引发局部炎症及狭窄。脐部肠道索带是由卵黄管发育异常所形成的,其存在可引起肠梗阻等疾病,通过常规检查很难明确病因,多在术中探查时明确。因此结合临床病例探讨其发病机制及诊疗措施对于该疾病的研究有着重大意义。本案报道1例脐部肠道索带引发肠梗阻的病例。现将整个治疗过程阐述如下。Intestinal obstruction refers to the failure of intestinal contents to pass through the intestines for various causes, and is a common disease in the clinic, which can be divided into: mechanical intestinal obstruction, dynamic intestinal obstruction and haemodynamic intestinal obstruction. In mechanical intestinal obstruction, in addition to tumours, intestinal wall torsion, intestinal adhesions, faecal impaction, roundworm formation and other common causes, there is also a relatively rare cause, that is, developmental anomalies lead to long-term presence of degenerative structures that irritate the intestinal tract and cause local inflammation and stenosis. The umbilical intestinal cord is formed by the abnormal development of the vitelline duct, and its presence can cause intestinal obstruction and other diseases. It is difficult to clarify the etiology of the disease through routine examination, and it is mostly clarified during intraoperative exploration. Therefore, exploring its pathogenesis and diagnostic and therapeutic measures in conjunction with clinical cases is of great significance to the study of this disease. This case reports a case of intestinal obstruction caused by umbilical intestinal cord. The whole treatment process is described as follows.
