Bifunctional reagents that serve as dual coupling partners with an activating species have emerged as valuable synthetic tools in organic chemistry.They allow for the development of diverse reaction modes with enhance...Bifunctional reagents that serve as dual coupling partners with an activating species have emerged as valuable synthetic tools in organic chemistry.They allow for the development of diverse reaction modes with enhanced efficiency and structural variability,which is in high demand for atom-economic and sustainable synthesis.Among them,bifunctional reagents containing Nheteroaryl groups have received much attention due to their ability to introduce privileged N-heteroaryl moieties into complex molecules that are otherwise challenging to access.Furthermore,these reagents have been employed under visible-light conditions to achieve various synthetic applications,enabling difunctionalization of alkenes,alkynes,and[1.1.1]propellanes under mild reaction conditions,providing access to highly functionalized N-heteroarenes.In this review,we provide an overview of the recent achievements and applications of photoinduced difunctionalization using bifunctional reagents containing N-heteroaryl groups.We systematically categorize the representative contributions in the field based on bifunctional reagents and their reactivity patterns.This review aims to highlight the potential of these reagents as powerful synthetic tools for sustainable and diverse synthesis.展开更多
Enhancing the stability and durability of metal-organic frameworks(MOFs)is vital for practical applications because many promising MOF materials suffer from phase transitions and/or structural decompositions with humi...Enhancing the stability and durability of metal-organic frameworks(MOFs)is vital for practical applications because many promising MOF materials suffer from phase transitions and/or structural decompositions with humidity being a particularly damaging condition.In mechanical engineering,the frame of buildings and furniture can be stabilized significantly by installing a truss beam.Employing the same principle,we functionalized the organic component of MOF-5 to contain a carbazole moiety that can act as a molecular truss beam by reaching across the corner and forming a stableπ–πinteraction with a phenyl group on the edge position of the MOF-skeleton.This structural support enhanced the stability of the MOF substantially,allowing the designed MOF to maintain compositional integrity under steam conditions at 90℃for~5 days.The unmodified MOF-5 shows clear signs of structural collapse after~1 h.展开更多
基金supported by the Institute for Basic Science(IBS-R010-A2)。
文摘Bifunctional reagents that serve as dual coupling partners with an activating species have emerged as valuable synthetic tools in organic chemistry.They allow for the development of diverse reaction modes with enhanced efficiency and structural variability,which is in high demand for atom-economic and sustainable synthesis.Among them,bifunctional reagents containing Nheteroaryl groups have received much attention due to their ability to introduce privileged N-heteroaryl moieties into complex molecules that are otherwise challenging to access.Furthermore,these reagents have been employed under visible-light conditions to achieve various synthetic applications,enabling difunctionalization of alkenes,alkynes,and[1.1.1]propellanes under mild reaction conditions,providing access to highly functionalized N-heteroarenes.In this review,we provide an overview of the recent achievements and applications of photoinduced difunctionalization using bifunctional reagents containing N-heteroaryl groups.We systematically categorize the representative contributions in the field based on bifunctional reagents and their reactivity patterns.This review aims to highlight the potential of these reagents as powerful synthetic tools for sustainable and diverse synthesis.
基金This work was supported by the Korea Science Academy of KAIST with funds from the Ministry of Science and ICT and the Institute for Basic Science (IBS-R010-A1) in Korea.
文摘Enhancing the stability and durability of metal-organic frameworks(MOFs)is vital for practical applications because many promising MOF materials suffer from phase transitions and/or structural decompositions with humidity being a particularly damaging condition.In mechanical engineering,the frame of buildings and furniture can be stabilized significantly by installing a truss beam.Employing the same principle,we functionalized the organic component of MOF-5 to contain a carbazole moiety that can act as a molecular truss beam by reaching across the corner and forming a stableπ–πinteraction with a phenyl group on the edge position of the MOF-skeleton.This structural support enhanced the stability of the MOF substantially,allowing the designed MOF to maintain compositional integrity under steam conditions at 90℃for~5 days.The unmodified MOF-5 shows clear signs of structural collapse after~1 h.
