Background: COVID-19, an infectious viral disease, has caused a global health crisis. Most cases remain asymptomatic. The majority of patients have mild symptoms while about 15% develop a severe form. The clinical spe...Background: COVID-19, an infectious viral disease, has caused a global health crisis. Most cases remain asymptomatic. The majority of patients have mild symptoms while about 15% develop a severe form. The clinical spectrum of SARS-CoV-2 infection appears broad, encompassing asymptomatic infection, upper respiratory tract symptoms, and severe viral pneumonia with respiratory failure that can lead to death. Laboratory tests play an important role in the management of COVID-19 patients. In addition to being essential for the diagnosis, several biological analyses make it possible to identify the inflammatory processes and the potential complications of this disease. This study attempted to identify biochemical assays that could help in the prognosis of the disease to ensure early management. Methods: This was a descriptive study. It focused on patients hospitalized for COVID-19 from March 19, 2020, to January 26, 2021, at the Infectious Disease Management Centre in Lomé (Togo). Medians were compared using the (Mann-Whitney and Wilcoxon) test and frequencies were compared using the Chi-square test or Fisher’s exact test. Results: We included 782 patients. The median age was 41 years IQR from 32 to 55. We observed several biochemical abnormalities in varying proportions for all biochemical parameters studied. Compared to non-serious patients, critically ill patients at admission had more frequently elevated urea, creatinine, transaminases, TG, GGT, CRP and blood glucose. Also, they had more frequent decreases in total cholesterol, HDL-c, blood chloride, and blood calcium. As for patients who died during hospitalization, compared with healed patients, they had more frequent elevations of urea, creatinine, AST, ALT, GGT. CRP and blood glucose. They also had a more frequent decrease in total cholesterol, HDL-c, blood chloride, blood calcium, and blood glucose (p = 0.025). Conclusion: This study shows that COVID-19 is a multi-organ systemic inflammatory viral disease that should be systematically investigated once the diagnosis is confirmed.展开更多
Background: Ophidian envenomation is common in Sub-Saharan Africa, and its management is hampered by the lack of access to healthcare services in rural areas, in particular the availability and appropriate use of anti...Background: Ophidian envenomation is common in Sub-Saharan Africa, and its management is hampered by the lack of access to healthcare services in rural areas, in particular the availability and appropriate use of antivenom. Rare cases of serious side effects following the administration of antivenom have been reported. This is the case for a young farmer from the central region of Togo, who experienced a second snake bite within four years, and in whom antivenom serotherapy led to severe allergic manifestations. Case presentation: This 24-year-old patient, with a history of antivenom and tetanus serotherapy, was admitted to the Centre Hospitalier Régional (CHR) of Sokodé for a snakebite that occurred 45 minutes earlier while working in the field. Clinical assessment on admission revealed grade 1 envenomation, characterized by local pain in the right upper limb, with no sign of complication. He received an intravenous infusion of antivenom serotherapy, which rapidly relieved the pain, allowing him to be discharged after 24 hours of hospital monitoring. However, he was readmitted five days later for a skin rash associated with generalized pruritus and edema of the face and the neck, which prompted his evacuation to the Sylvanus Olympio University Hospital. He was diagnosed with a hypersensitivity-type allergic reaction to antivenom serum. Symptomatic treatment with antihistamines resulted in a favourable outcome after five days in the hospital. Conclusion: This young farmer developed a severe allergic reaction following a second course of antivenom serotherapy for low-grade ophidian envenomation. Although the efficacy of antivenom serum is undeniable in the management of snakebites, its use should be guided by a sound clinical assessment and framed by rigorous monitoring, especially in people sensitized to antivenom or antitoxin serotherapy. This highlights the importance of training healthcare staff alongside the availability of anti-venomous sera at peripheral healthcare centres.展开更多
Introduction: In December 2021, Beninese soldiers were victims of armed terrorist attacks. This study aims to determine the psychological impact of the events experienced on the victims in order to better prevent post...Introduction: In December 2021, Beninese soldiers were victims of armed terrorist attacks. This study aims to determine the psychological impact of the events experienced on the victims in order to better prevent post-traumatic stress disorder. Materials and methods: This is a descriptive cross-sectional study conducted from December 13 to 14, 2021, i.e. 12 days after the oldest event and 4 days after the most recent. The experience of the event was assessed with the Peritraumatic Distress Inventory and the Peritraumatic Dissociation Experiences Questionnaire. Symptoms experienced in the hours and days after the event were assessed with the Revised Event Impact Scale. Results: 36 soldiers were included out of the 38 survivors, i.e. 94.73%. They were 51.43% victims of the night assault, 37.14% of the ambush on patrol and 11.43% of the explosion of vehicle on mine, all male. The average age was 31 years with extremes of 25 and 49 years. The 25 - 30 year olds predominated, 52.78%. 100% of soldiers had significant peritraumatic dissociation, of which 94.44% also had significant peritraumatic distress. 100% of the soldiers had manifestations of intrusion, 89% of manifestations of avoidance and 83% of manifestations of hyperexcitation. 88.89% had an index for acute stress including 100% of victims of night assault and vehicle explosion on mine. Conclusion: This study shows a high prevalence of peritraumatic reactions, recognized factors favoring post-traumatic stress disorder, and the interest of their evaluation for medical and psychological help adapted to the victims.展开更多
Introduction: According to the WHO, suicide is a real public health problem worldwide, and several risk factors have been identified, including pain and chronic illness. Objective: The aim of this study was to assess ...Introduction: According to the WHO, suicide is a real public health problem worldwide, and several risk factors have been identified, including pain and chronic illness. Objective: The aim of this study was to assess the suicidal risk in sickle-cell patients. Method: This was a descriptive and analytical cross-sectional study of sickle-cell patients followed up at the University Clinic of Blood Diseases of Hubert Koutoukou Maga National University Hospital Center from August 2022 to November 2022. The instrument used was the Ducher suicide risk self-assessment scale. Results: A total of 65 patients were included. Mean age was 27.04 ± 1.95 years, with extremes of 16 and 50 years, and a peak of 47.69% in the 20 - 30 age group. Women predominated (58.46%), with a sex ratio of 0.71. Somatic complaints accounted for 41.54% of patients’ visits, including 21.54% for pain. Suicidal risk was positive in 44.62%, including 13.85% for severe suicidal risk, and 20% attributed their desire to die to pain. The factor associated with positive suicidal risk was single parenthood (p = 0.02). Of those with a positive suicidal risk, 46% had shared the intention with close relatives (family and friends), but none had used medical services. Conclusion: These data demonstrate the high prevalence of suicidal risk among people with sickle cell disease, and therefore the need for psychosocial intervention in this specific population in Benin.展开更多
<strong>Introduction:</strong> Glaucoma is a major cause of irreversible blindness worldwide. Early detection and awareness are essential to reduce the impact on eye health. The aim of this study is to ass...<strong>Introduction:</strong> Glaucoma is a major cause of irreversible blindness worldwide. Early detection and awareness are essential to reduce the impact on eye health. The aim of this study is to assess the knowledge, attitudes and practices of health care staff about glaucoma in Lomé. <strong>Materials and Methods:</strong> This was a prospective cross-sectional and descriptive study including health care staff in Lomé, from October 1st to December 31st, 2020, for a period of 3 months. After their agreement, the officers responded to questions based on a survey sheet. <strong>Results:</strong> A total of 169 agents from 3 centers in Lomé, i.e. the Sylvanus Olympio University Teaching Hospital, the Campus University teaching Hospital and the Bè Hospital were involved. 50.9% of the agents were male versus 49.1% female, i.e. a ratio of 1.04. The average age was 33.66 ± 10.45 years. 46.10% were doctors versus 53.90% paramedics. 58.60% had at most 5 years of experience against 41.40% who had more than 5 years of experience. 53.80% defined glaucoma as ocular hypertension while 17.20% defined it as optic nerve disease. 46.20% did not know that there were many types of glaucomas compared to 53.20% who knew that there are many types of glaucomas. 92.30% knew that glaucoma can lead to cause visual loss. Regarding attitudes and practices about glaucoma, 91.70% declared that the follow-up should be done by the ophthalmologist, 81.10% thought that it would be necessary to be checked by the doctor only every 6 months. Finally, 65.08% declared that they had to use eye drops for life for the treatment. <strong>Conclusion:</strong> Steps should be taken to educate staff more about glaucoma attitudes and practices and also plan for action in the population.展开更多
<strong>Background:</strong> Large papillary excavations constitute a true differential diagnosis of glaucoma in our environments. <strong>Aim:</strong> To present a clinical case of large papi...<strong>Background:</strong> Large papillary excavations constitute a true differential diagnosis of glaucoma in our environments. <strong>Aim:</strong> To present a clinical case of large papillary excavation simulating glaucomatous optic neuropathy in a young subject. <strong>Case Presentation:</strong> The ophthalmologic examination made it possible to note a visual acuity of LogMar 0.00, ocular hypertonia and a large papillary excavation in both eyes. The visual field noted bilateral perimetric involvement suggesting optic neuropathy. Optical coherence tomography (OCT) of the ganglion complex revealed an absence of involvement of the ganglion complex and the ganglion ridge essential to evoke optic neuropathy. An ocular hypotonizing treatment made it possible to normalize the intraocular pressure. <strong>Conclusion:</strong> The particularity of this observation lies in the fact that the perimeter involvement that preceded any involvement can simulate a glaucomatous involvement. Functional damage to the visual field must be correlated with structural damage to suggest glaucomatous damage in our ophthalmic patients.展开更多
Background: Diabetic patients have risk of kidney disease. The aim of this study was to assess the level of renal risk in our study population and to identify the associated predictive factors. Methods: It was a descr...Background: Diabetic patients have risk of kidney disease. The aim of this study was to assess the level of renal risk in our study population and to identify the associated predictive factors. Methods: It was a descriptive and analytical cross-sectional study carried out over 5 years (January 1, 2016 to December 31, 2020). All patients were included regardless of the duration of diabetes and having achieved at least one serum creatinine and at least two (2) proteinuria in the 24 hours over a period of at least three months. The level of renal risk was assessed using the KDIGO 2012 classification. Results: A total of 320 patient medical files were retained. The sex ratio M/F was 1.2. The average age was 57.2 ± 11.8 years. Hypertension was the most common comorbidity (84.4%). Diabetic nephropathy was found in 177 patients, a frequency of 42.8%. The very significant renal risk was found in 174 patients (54.4%). In multivariate logistic regression, the risk factors significantly associated with renal risk were: Male sex (OR = 2.50;95% CI = 1.29 - 4.84, p-value = 0.006);microangiopathy (OR = 5.54;95% CI = 1.82 - 16.85 p = 0.002) and beta-blockers (OR = 5.64;95% CI = 1.04 - 30.53 p = 0.004). The Oral Antidiabetes (OR = 0.23;95% CI = 0.10 - 0.55, p = 0.001), the blockers of Renin-Angiotensin system (OR = 0.58;95% CI = 0.41 - 0.90, p = 0.040) and the average socioeconomic level (OR = 0.50;95% CI = 0.25 - 0.98, p = 0.044) were rather the protective factors.展开更多
Cancer is common in our setting and represents a real public health concern in sub-Saharan Africa. This work aimed to assess the role of computed tomography in the follow-up of patients treated for cancer in Togo. Thi...Cancer is common in our setting and represents a real public health concern in sub-Saharan Africa. This work aimed to assess the role of computed tomography in the follow-up of patients treated for cancer in Togo. This was a retrospective descriptive study carried out over a period of one year, on patients with cancer, treated in the medical oncology unit of </span><i><span style="font-family:Verdana;">CHU</span></i> <i><span style="font-family:Verdana;">Sylvanus Olympio</span></i><span style="font-family:Verdana;"> and having undergone at least two CT scans after cancer treatment. Computed tomography evaluation was performed according to the RECIST 1.1 guidelines. We had found</span><b> </b><span style="font-family:Verdana;">46 patients. The mean age of the patients was 54.22 years with a female predominance (sex ratio 1:2.5). Cancers mainly involved the urogenital system (60.8%) followed by the digestive system (28.3%). Carcinoma represented 93.5% of cases, mainly adenocarcinoma (45.7%). 74 target lesions were present at baseline, with 18.9% and 11.6% disappearing at the first and second assessments respectively. 36 non-target lesions were present at baseline, with 25% and 22.2% disappearing at the first and second assessments respectively. New lesions were found in the abdominal region in 54.5% of cases and in the thoracic region in 41.3% at the first and second assessments respectively. 58.7% of patients had a stable disease at the first assessment and 39.1% had progression at the second assessment. 50% of them had received chemotherapy in combination with surgery. Computed tomography using the RECIST 1.1 guidelines is a necessity in monitoring tumor extensions and in the follow-up of cancer patients.展开更多
<strong>Background:</strong> Ocular coloboma is the product of an error in the fetal fissure closure, normally occurring between the fifth and sixth weeks of gestation <a href="#R1" target=&qu...<strong>Background:</strong> Ocular coloboma is the product of an error in the fetal fissure closure, normally occurring between the fifth and sixth weeks of gestation <a href="#R1" target="_blank">[1]</a>. It may involve the cornea, iris, zonula, ciliary body, choroid, retina and optic nerve. The incidence of this syndrome is 0.7 per 10,000 live-births <a href="#R1" target="_blank">[1]</a>. The aim of this observation is to present the first case of bilateral coloboma of the iris <a href="#R1" target="_blank">[1]</a>. This case was associated with an ametropia causing a decrease in visual acuity. <strong>Case Presentation:</strong> This was a clinical observation concerning a young 12-year-old patient who consulted for blurring of vision which had progressed for approximately 2 years. The ophthalmologic examination revealed an ametropia with a bilateral notch of the pupillary rim suggesting a bilateral coloboma. There was no association with another coloboma such as chorioretinal coloboma which is quite common and is accompanied frequently by visual symptoms. <strong>Conclusion:</strong> A visual impairment of the child can indicate ametropia. However, other congenital anomalies can be discovered as was the case in this clinical observation.展开更多
Breast cancer represents a real public health problem due to its increasing frequency, its seriousness and its psycho-social implications. The aims of this study were to determine the level of awareness of women on th...Breast cancer represents a real public health problem due to its increasing frequency, its seriousness and its psycho-social implications. The aims of this study were to determine the level of awareness of women on the performance of mammography in the diagnosis and screening for breast cancer. This was a cross-sectional study over a period of 4 months (from October 1, 2016 to January 31, 2017) in Togo. It consisted in completing a questionnaire distributed to women above 30 years of age. The mean age of the women was 42 years. 88.8% of them had heard of breast cancer. There was a link between age, occupation, level of education and awareness of breast cancer. Only 20.8% of women had heard of mammography, with a link between awareness of mammography and age, occupation, and level of education. A link was noted between awareness of breast cancer and awareness of mammography. Information on mammographic breast cancer screening is inadequate in Togo.展开更多
<strong>Background:</strong> Druses of the papilla constitute abnormal deposits of calcified hyaline material at the level of the head of the optic nerve. They can be superficial or deep. <strong>Aim...<strong>Background:</strong> Druses of the papilla constitute abnormal deposits of calcified hyaline material at the level of the head of the optic nerve. They can be superficial or deep. <strong>Aim:</strong> The aim of this study is to show the utility of ocular ultrasound in ophthalmology in underdeveloped countries for the characterization of optic disc druse. <strong>Case Presentation:</strong> Our study relates to a clinical observation of buried papillary druses diagnosed by ocular ultrasound. The ophthalmologic examination revealed an aspect of false papillary edema in the fundus. The ocular ultrasound revealed hyperechogenic deposits buried in the papillary margins, which suggests the deep papillary druses. <strong>Conclusion:</strong> Ocular ultrasound still has a prominent place in the diagnosis of certain eye conditions despite the new sophisticated means available to ophthalmology to date.展开更多
文摘Background: COVID-19, an infectious viral disease, has caused a global health crisis. Most cases remain asymptomatic. The majority of patients have mild symptoms while about 15% develop a severe form. The clinical spectrum of SARS-CoV-2 infection appears broad, encompassing asymptomatic infection, upper respiratory tract symptoms, and severe viral pneumonia with respiratory failure that can lead to death. Laboratory tests play an important role in the management of COVID-19 patients. In addition to being essential for the diagnosis, several biological analyses make it possible to identify the inflammatory processes and the potential complications of this disease. This study attempted to identify biochemical assays that could help in the prognosis of the disease to ensure early management. Methods: This was a descriptive study. It focused on patients hospitalized for COVID-19 from March 19, 2020, to January 26, 2021, at the Infectious Disease Management Centre in Lomé (Togo). Medians were compared using the (Mann-Whitney and Wilcoxon) test and frequencies were compared using the Chi-square test or Fisher’s exact test. Results: We included 782 patients. The median age was 41 years IQR from 32 to 55. We observed several biochemical abnormalities in varying proportions for all biochemical parameters studied. Compared to non-serious patients, critically ill patients at admission had more frequently elevated urea, creatinine, transaminases, TG, GGT, CRP and blood glucose. Also, they had more frequent decreases in total cholesterol, HDL-c, blood chloride, and blood calcium. As for patients who died during hospitalization, compared with healed patients, they had more frequent elevations of urea, creatinine, AST, ALT, GGT. CRP and blood glucose. They also had a more frequent decrease in total cholesterol, HDL-c, blood chloride, blood calcium, and blood glucose (p = 0.025). Conclusion: This study shows that COVID-19 is a multi-organ systemic inflammatory viral disease that should be systematically investigated once the diagnosis is confirmed.
文摘Background: Ophidian envenomation is common in Sub-Saharan Africa, and its management is hampered by the lack of access to healthcare services in rural areas, in particular the availability and appropriate use of antivenom. Rare cases of serious side effects following the administration of antivenom have been reported. This is the case for a young farmer from the central region of Togo, who experienced a second snake bite within four years, and in whom antivenom serotherapy led to severe allergic manifestations. Case presentation: This 24-year-old patient, with a history of antivenom and tetanus serotherapy, was admitted to the Centre Hospitalier Régional (CHR) of Sokodé for a snakebite that occurred 45 minutes earlier while working in the field. Clinical assessment on admission revealed grade 1 envenomation, characterized by local pain in the right upper limb, with no sign of complication. He received an intravenous infusion of antivenom serotherapy, which rapidly relieved the pain, allowing him to be discharged after 24 hours of hospital monitoring. However, he was readmitted five days later for a skin rash associated with generalized pruritus and edema of the face and the neck, which prompted his evacuation to the Sylvanus Olympio University Hospital. He was diagnosed with a hypersensitivity-type allergic reaction to antivenom serum. Symptomatic treatment with antihistamines resulted in a favourable outcome after five days in the hospital. Conclusion: This young farmer developed a severe allergic reaction following a second course of antivenom serotherapy for low-grade ophidian envenomation. Although the efficacy of antivenom serum is undeniable in the management of snakebites, its use should be guided by a sound clinical assessment and framed by rigorous monitoring, especially in people sensitized to antivenom or antitoxin serotherapy. This highlights the importance of training healthcare staff alongside the availability of anti-venomous sera at peripheral healthcare centres.
文摘Introduction: In December 2021, Beninese soldiers were victims of armed terrorist attacks. This study aims to determine the psychological impact of the events experienced on the victims in order to better prevent post-traumatic stress disorder. Materials and methods: This is a descriptive cross-sectional study conducted from December 13 to 14, 2021, i.e. 12 days after the oldest event and 4 days after the most recent. The experience of the event was assessed with the Peritraumatic Distress Inventory and the Peritraumatic Dissociation Experiences Questionnaire. Symptoms experienced in the hours and days after the event were assessed with the Revised Event Impact Scale. Results: 36 soldiers were included out of the 38 survivors, i.e. 94.73%. They were 51.43% victims of the night assault, 37.14% of the ambush on patrol and 11.43% of the explosion of vehicle on mine, all male. The average age was 31 years with extremes of 25 and 49 years. The 25 - 30 year olds predominated, 52.78%. 100% of soldiers had significant peritraumatic dissociation, of which 94.44% also had significant peritraumatic distress. 100% of the soldiers had manifestations of intrusion, 89% of manifestations of avoidance and 83% of manifestations of hyperexcitation. 88.89% had an index for acute stress including 100% of victims of night assault and vehicle explosion on mine. Conclusion: This study shows a high prevalence of peritraumatic reactions, recognized factors favoring post-traumatic stress disorder, and the interest of their evaluation for medical and psychological help adapted to the victims.
文摘Introduction: According to the WHO, suicide is a real public health problem worldwide, and several risk factors have been identified, including pain and chronic illness. Objective: The aim of this study was to assess the suicidal risk in sickle-cell patients. Method: This was a descriptive and analytical cross-sectional study of sickle-cell patients followed up at the University Clinic of Blood Diseases of Hubert Koutoukou Maga National University Hospital Center from August 2022 to November 2022. The instrument used was the Ducher suicide risk self-assessment scale. Results: A total of 65 patients were included. Mean age was 27.04 ± 1.95 years, with extremes of 16 and 50 years, and a peak of 47.69% in the 20 - 30 age group. Women predominated (58.46%), with a sex ratio of 0.71. Somatic complaints accounted for 41.54% of patients’ visits, including 21.54% for pain. Suicidal risk was positive in 44.62%, including 13.85% for severe suicidal risk, and 20% attributed their desire to die to pain. The factor associated with positive suicidal risk was single parenthood (p = 0.02). Of those with a positive suicidal risk, 46% had shared the intention with close relatives (family and friends), but none had used medical services. Conclusion: These data demonstrate the high prevalence of suicidal risk among people with sickle cell disease, and therefore the need for psychosocial intervention in this specific population in Benin.
文摘<strong>Introduction:</strong> Glaucoma is a major cause of irreversible blindness worldwide. Early detection and awareness are essential to reduce the impact on eye health. The aim of this study is to assess the knowledge, attitudes and practices of health care staff about glaucoma in Lomé. <strong>Materials and Methods:</strong> This was a prospective cross-sectional and descriptive study including health care staff in Lomé, from October 1st to December 31st, 2020, for a period of 3 months. After their agreement, the officers responded to questions based on a survey sheet. <strong>Results:</strong> A total of 169 agents from 3 centers in Lomé, i.e. the Sylvanus Olympio University Teaching Hospital, the Campus University teaching Hospital and the Bè Hospital were involved. 50.9% of the agents were male versus 49.1% female, i.e. a ratio of 1.04. The average age was 33.66 ± 10.45 years. 46.10% were doctors versus 53.90% paramedics. 58.60% had at most 5 years of experience against 41.40% who had more than 5 years of experience. 53.80% defined glaucoma as ocular hypertension while 17.20% defined it as optic nerve disease. 46.20% did not know that there were many types of glaucomas compared to 53.20% who knew that there are many types of glaucomas. 92.30% knew that glaucoma can lead to cause visual loss. Regarding attitudes and practices about glaucoma, 91.70% declared that the follow-up should be done by the ophthalmologist, 81.10% thought that it would be necessary to be checked by the doctor only every 6 months. Finally, 65.08% declared that they had to use eye drops for life for the treatment. <strong>Conclusion:</strong> Steps should be taken to educate staff more about glaucoma attitudes and practices and also plan for action in the population.
文摘<strong>Background:</strong> Large papillary excavations constitute a true differential diagnosis of glaucoma in our environments. <strong>Aim:</strong> To present a clinical case of large papillary excavation simulating glaucomatous optic neuropathy in a young subject. <strong>Case Presentation:</strong> The ophthalmologic examination made it possible to note a visual acuity of LogMar 0.00, ocular hypertonia and a large papillary excavation in both eyes. The visual field noted bilateral perimetric involvement suggesting optic neuropathy. Optical coherence tomography (OCT) of the ganglion complex revealed an absence of involvement of the ganglion complex and the ganglion ridge essential to evoke optic neuropathy. An ocular hypotonizing treatment made it possible to normalize the intraocular pressure. <strong>Conclusion:</strong> The particularity of this observation lies in the fact that the perimeter involvement that preceded any involvement can simulate a glaucomatous involvement. Functional damage to the visual field must be correlated with structural damage to suggest glaucomatous damage in our ophthalmic patients.
文摘Background: Diabetic patients have risk of kidney disease. The aim of this study was to assess the level of renal risk in our study population and to identify the associated predictive factors. Methods: It was a descriptive and analytical cross-sectional study carried out over 5 years (January 1, 2016 to December 31, 2020). All patients were included regardless of the duration of diabetes and having achieved at least one serum creatinine and at least two (2) proteinuria in the 24 hours over a period of at least three months. The level of renal risk was assessed using the KDIGO 2012 classification. Results: A total of 320 patient medical files were retained. The sex ratio M/F was 1.2. The average age was 57.2 ± 11.8 years. Hypertension was the most common comorbidity (84.4%). Diabetic nephropathy was found in 177 patients, a frequency of 42.8%. The very significant renal risk was found in 174 patients (54.4%). In multivariate logistic regression, the risk factors significantly associated with renal risk were: Male sex (OR = 2.50;95% CI = 1.29 - 4.84, p-value = 0.006);microangiopathy (OR = 5.54;95% CI = 1.82 - 16.85 p = 0.002) and beta-blockers (OR = 5.64;95% CI = 1.04 - 30.53 p = 0.004). The Oral Antidiabetes (OR = 0.23;95% CI = 0.10 - 0.55, p = 0.001), the blockers of Renin-Angiotensin system (OR = 0.58;95% CI = 0.41 - 0.90, p = 0.040) and the average socioeconomic level (OR = 0.50;95% CI = 0.25 - 0.98, p = 0.044) were rather the protective factors.
文摘Cancer is common in our setting and represents a real public health concern in sub-Saharan Africa. This work aimed to assess the role of computed tomography in the follow-up of patients treated for cancer in Togo. This was a retrospective descriptive study carried out over a period of one year, on patients with cancer, treated in the medical oncology unit of </span><i><span style="font-family:Verdana;">CHU</span></i> <i><span style="font-family:Verdana;">Sylvanus Olympio</span></i><span style="font-family:Verdana;"> and having undergone at least two CT scans after cancer treatment. Computed tomography evaluation was performed according to the RECIST 1.1 guidelines. We had found</span><b> </b><span style="font-family:Verdana;">46 patients. The mean age of the patients was 54.22 years with a female predominance (sex ratio 1:2.5). Cancers mainly involved the urogenital system (60.8%) followed by the digestive system (28.3%). Carcinoma represented 93.5% of cases, mainly adenocarcinoma (45.7%). 74 target lesions were present at baseline, with 18.9% and 11.6% disappearing at the first and second assessments respectively. 36 non-target lesions were present at baseline, with 25% and 22.2% disappearing at the first and second assessments respectively. New lesions were found in the abdominal region in 54.5% of cases and in the thoracic region in 41.3% at the first and second assessments respectively. 58.7% of patients had a stable disease at the first assessment and 39.1% had progression at the second assessment. 50% of them had received chemotherapy in combination with surgery. Computed tomography using the RECIST 1.1 guidelines is a necessity in monitoring tumor extensions and in the follow-up of cancer patients.
文摘<strong>Background:</strong> Ocular coloboma is the product of an error in the fetal fissure closure, normally occurring between the fifth and sixth weeks of gestation <a href="#R1" target="_blank">[1]</a>. It may involve the cornea, iris, zonula, ciliary body, choroid, retina and optic nerve. The incidence of this syndrome is 0.7 per 10,000 live-births <a href="#R1" target="_blank">[1]</a>. The aim of this observation is to present the first case of bilateral coloboma of the iris <a href="#R1" target="_blank">[1]</a>. This case was associated with an ametropia causing a decrease in visual acuity. <strong>Case Presentation:</strong> This was a clinical observation concerning a young 12-year-old patient who consulted for blurring of vision which had progressed for approximately 2 years. The ophthalmologic examination revealed an ametropia with a bilateral notch of the pupillary rim suggesting a bilateral coloboma. There was no association with another coloboma such as chorioretinal coloboma which is quite common and is accompanied frequently by visual symptoms. <strong>Conclusion:</strong> A visual impairment of the child can indicate ametropia. However, other congenital anomalies can be discovered as was the case in this clinical observation.
文摘Breast cancer represents a real public health problem due to its increasing frequency, its seriousness and its psycho-social implications. The aims of this study were to determine the level of awareness of women on the performance of mammography in the diagnosis and screening for breast cancer. This was a cross-sectional study over a period of 4 months (from October 1, 2016 to January 31, 2017) in Togo. It consisted in completing a questionnaire distributed to women above 30 years of age. The mean age of the women was 42 years. 88.8% of them had heard of breast cancer. There was a link between age, occupation, level of education and awareness of breast cancer. Only 20.8% of women had heard of mammography, with a link between awareness of mammography and age, occupation, and level of education. A link was noted between awareness of breast cancer and awareness of mammography. Information on mammographic breast cancer screening is inadequate in Togo.
文摘<strong>Background:</strong> Druses of the papilla constitute abnormal deposits of calcified hyaline material at the level of the head of the optic nerve. They can be superficial or deep. <strong>Aim:</strong> The aim of this study is to show the utility of ocular ultrasound in ophthalmology in underdeveloped countries for the characterization of optic disc druse. <strong>Case Presentation:</strong> Our study relates to a clinical observation of buried papillary druses diagnosed by ocular ultrasound. The ophthalmologic examination revealed an aspect of false papillary edema in the fundus. The ocular ultrasound revealed hyperechogenic deposits buried in the papillary margins, which suggests the deep papillary druses. <strong>Conclusion:</strong> Ocular ultrasound still has a prominent place in the diagnosis of certain eye conditions despite the new sophisticated means available to ophthalmology to date.
