Background Immunization is a cornerstone of public health.Despite great success,China’s National Immunization Program(NIP)faces challenges,such as the integration of several World Health Organization-recommended vacc...Background Immunization is a cornerstone of public health.Despite great success,China’s National Immunization Program(NIP)faces challenges,such as the integration of several World Health Organization-recommended vaccines and other systemic issues.The Innovation Laboratory for Vaccine Delivery Research(VaxLab),supported by the Bill&Melinda Gates Foundation and established in 2021 at Duke Kunshan University,focuses on enhancing China’s NIP through research and policy advocacy.This editorial aims to summarize the key findings of the manuscripts published in the collection contributed by VaxLab team and set the future research agenda.Key findings The collection contains eleven manuscripts discussing China’s immunization landscape and strategies to improve coverage,particularly for non-NIP vaccines like human papillomavirus vaccine(HPV),pneumococcal conjugate vaccine(PCV),Haemophilus influenzae type b vaccine(Hib),and rotavirus vaccines.Key findings include:(i)The COVID-19 vaccination campaign demonstrated China’s capacity for rapid,large-scale immunization efforts,suggesting potential for broader vaccine coverage improvements;(ii)Efforts in combating cervical cancer through the HPV vaccine indicate progress but also highlight challenges like vaccine supply and equitable access;(iii)The lag in adopting higher-valent paediatric combination vaccines in China needs attention to address regulatory and health system hurdles;(iv)Disparities in access to non-NIP vaccines underscore the need for government initiatives to improve vaccine coverage,especially for remote areas and marginalized populations;(v)Original studies emphasize the influence of caregivers’knowledge,health workers’financial incentives,and concerns about vaccine efficacy on immunization rates;(vi)Case studies from the Weifang City of China and Indonesia to introduce PCV offer insights on successful vaccine introduction strategies and the impact of innovative financing and government support.Conclusion The articles emphasize the need for government leadership,strategic policymaking,and public awareness to enhance vaccine coverage and equity.The VaxLab will continue strengthening China’s NIP by focusing on vaccine financing,emphasizing diversity,equity,and inclusion,and improving maternal vaccination coverage.Research will extend to Southeast Asian and Western Pacific regions,especially in middle-income countries facing challenges in vaccine financing and delivery.The collective efforts outlined in this collection show a commitment to evolving and adapting immunization strategies to meet global health goals and to provide equitable access to vaccines for all.展开更多
1.Introduction.The Immunization Agenda 2030 outlined the importance of capacity building for researchers,regulators and public health officials at national,regional and local levels in its multiple strategic prioritie...1.Introduction.The Immunization Agenda 2030 outlined the importance of capacity building for researchers,regulators and public health officials at national,regional and local levels in its multiple strategic priorities for building an effective immunization programme[1].The mission of University of Chinese Academy of Sciences focuses on frontier science and applied biotechnology to address the challenges for both the development of the country as well as world sustainability,facing the forefront of the global scientific and technological advances,to compete on the main economic battlefield,and to address the major needs of the country and for the lives and health of the people.展开更多
Forty years ago,smallpox was declared eradicated by the World Health Organization(WHO).As D.A.Henderson,Director of the Smallpox Eradication Programme at the WHO quoted from the 33^(rd) World Health Assembly(1980)(1),...Forty years ago,smallpox was declared eradicated by the World Health Organization(WHO).As D.A.Henderson,Director of the Smallpox Eradication Programme at the WHO quoted from the 33^(rd) World Health Assembly(1980)(1),“...the world and all its peoples have won freedom from smallpox...a most devastating disease...since earliest time,leaving death,blindness,and disfigurement in its wake and which only a decade ago was rampant in Africa,Asia and South America.”展开更多
文摘Background Immunization is a cornerstone of public health.Despite great success,China’s National Immunization Program(NIP)faces challenges,such as the integration of several World Health Organization-recommended vaccines and other systemic issues.The Innovation Laboratory for Vaccine Delivery Research(VaxLab),supported by the Bill&Melinda Gates Foundation and established in 2021 at Duke Kunshan University,focuses on enhancing China’s NIP through research and policy advocacy.This editorial aims to summarize the key findings of the manuscripts published in the collection contributed by VaxLab team and set the future research agenda.Key findings The collection contains eleven manuscripts discussing China’s immunization landscape and strategies to improve coverage,particularly for non-NIP vaccines like human papillomavirus vaccine(HPV),pneumococcal conjugate vaccine(PCV),Haemophilus influenzae type b vaccine(Hib),and rotavirus vaccines.Key findings include:(i)The COVID-19 vaccination campaign demonstrated China’s capacity for rapid,large-scale immunization efforts,suggesting potential for broader vaccine coverage improvements;(ii)Efforts in combating cervical cancer through the HPV vaccine indicate progress but also highlight challenges like vaccine supply and equitable access;(iii)The lag in adopting higher-valent paediatric combination vaccines in China needs attention to address regulatory and health system hurdles;(iv)Disparities in access to non-NIP vaccines underscore the need for government initiatives to improve vaccine coverage,especially for remote areas and marginalized populations;(v)Original studies emphasize the influence of caregivers’knowledge,health workers’financial incentives,and concerns about vaccine efficacy on immunization rates;(vi)Case studies from the Weifang City of China and Indonesia to introduce PCV offer insights on successful vaccine introduction strategies and the impact of innovative financing and government support.Conclusion The articles emphasize the need for government leadership,strategic policymaking,and public awareness to enhance vaccine coverage and equity.The VaxLab will continue strengthening China’s NIP by focusing on vaccine financing,emphasizing diversity,equity,and inclusion,and improving maternal vaccination coverage.Research will extend to Southeast Asian and Western Pacific regions,especially in middle-income countries facing challenges in vaccine financing and delivery.The collective efforts outlined in this collection show a commitment to evolving and adapting immunization strategies to meet global health goals and to provide equitable access to vaccines for all.
基金supported by the University of Chinese Academy of Sciences Education Foundation and the Bill&Melinda Gates Foundation(INV-008950)。
文摘1.Introduction.The Immunization Agenda 2030 outlined the importance of capacity building for researchers,regulators and public health officials at national,regional and local levels in its multiple strategic priorities for building an effective immunization programme[1].The mission of University of Chinese Academy of Sciences focuses on frontier science and applied biotechnology to address the challenges for both the development of the country as well as world sustainability,facing the forefront of the global scientific and technological advances,to compete on the main economic battlefield,and to address the major needs of the country and for the lives and health of the people.
文摘Forty years ago,smallpox was declared eradicated by the World Health Organization(WHO).As D.A.Henderson,Director of the Smallpox Eradication Programme at the WHO quoted from the 33^(rd) World Health Assembly(1980)(1),“...the world and all its peoples have won freedom from smallpox...a most devastating disease...since earliest time,leaving death,blindness,and disfigurement in its wake and which only a decade ago was rampant in Africa,Asia and South America.”
