Since its inception,Animal Models and Experimental Medicine(AMEM)has received 632 articles in total from 52 countries and regions includ-ing China,Iran,the United States,India,Nigeria,Israel,Germany,Iraq,Italy,Japan,A...Since its inception,Animal Models and Experimental Medicine(AMEM)has received 632 articles in total from 52 countries and regions includ-ing China,Iran,the United States,India,Nigeria,Israel,Germany,Iraq,Italy,Japan,Australia,Bangladesh,Belgium,Brazil,and Canada,among others.AMEM has become an important international exchange plat-form for innovative research achievements in the field of laboratory animal science and basic medicine.展开更多
These Chinese National Guidelines(GB/T 35892-20181)were issued February 06,2018 and became effective September 01,2018.The authors recognized the urgent need for an authentic English translation to inform the internat...These Chinese National Guidelines(GB/T 35892-20181)were issued February 06,2018 and became effective September 01,2018.The authors recognized the urgent need for an authentic English translation to inform the international community of the compliance requirements in China.It was appreciated that the final translation must reflect the specialist understanding of those working under the Guideline whilst remaining faithful to the meaning of the original Chinese text.A three-step translation process was therefore determined.Step 1:A professional interpretation service(KL Communications,UK)was commissioned to prepare a literal translation of the Chinese text.Supportive documents were provided which explained specialist terminology.This translation was checked by two bilingual experts.Step 2:A workshop was held in Nanjing in May 2019 to which were invited experts in laboratory animal welfare and ethical use.These included international native English-speaking and Chinese-speaking delegates.The delegates worked in multilingual teams to review sections of the literal translation ahead of the workshop,and to agree an authentic interpretation during the workshop.Step 3:Following the workshop,three bilingual experts(two native Chinese speakers and one native English speaker)reviewed the entire document to ensure consistency of terminology and general accuracy.This document is thus not a“literal translation”but an“accurate interpretation”of the original text.Any challenge of work being performed under these Guidelines should rely on the Chinese text in the first place.However,this translation may be used as mitigating evidence,especially where those performing the work are non-Chinese speakers.展开更多
1|INTRODUCTION For decades,experimental animal models have been powerful tools for biomedical research and have supported most of the physiological or medical achievements recognized by Nobel Prizes,including the rese...1|INTRODUCTION For decades,experimental animal models have been powerful tools for biomedical research and have supported most of the physiological or medical achievements recognized by Nobel Prizes,including the research that won this year's Physiology or Medicine Prize.On 4th October 2021,the Nobel Prize in Physiology or Medicine 2021 was awarded jointly to David Julius and Ardem Patapoutian"for their discoveries of receptors for temperature and touch."1 Their discoveries have profoundly changed our view of how we sense the world around us2.展开更多
The 2nd Longtan Science Conference and the 40th anniversary of the Institute of Laboratory Animal Sciences,Chinese Academy of Medical Sciences&Comparative Medicine Center,Peking Union Medical College.On November 1...The 2nd Longtan Science Conference and the 40th anniversary of the Institute of Laboratory Animal Sciences,Chinese Academy of Medical Sciences&Comparative Medicine Center,Peking Union Medical College.On November 19-20,2020,the 2nd Longtan Science Conference and the 40th anniversary celebrations of the Institute of Laboratory Animal Sciences,Chinese Academy of Medical Sciences&Comparative Medicine Center,Peking Union Medical College(hereinafter referred to as"ILAS")were held in Beijing.The conference was jointly organized by the Institute and the Chinese Association for Laboratory Animal Sciences.展开更多
According to the traditional Chinese zodiac,2023 is the Year of the Rabbit,which holds the meaning of life and hope due to the rabbit's vigorous reproductive ability.Over the past 5 years AMEM has flourished,initi...According to the traditional Chinese zodiac,2023 is the Year of the Rabbit,which holds the meaning of life and hope due to the rabbit's vigorous reproductive ability.Over the past 5 years AMEM has flourished,initial hopes have been realized and the journal has gone from strength to strength.Following the gradual rise in submissions and the journal's increasing influence,in 2022 AMEM changed from quarterly to bimonthly,and successively launched seven themed sections-columns-includ-ing neurodegenerative disease,cardiovascular disease,and so on.展开更多
At the first issue of the year 2021,I would like to extend my sincere gratitude for your continued support and attention to Animal Models and Experimental Medicine(AMEM)journal.On behalf of AMEM,I would like to wish y...At the first issue of the year 2021,I would like to extend my sincere gratitude for your continued support and attention to Animal Models and Experimental Medicine(AMEM)journal.On behalf of AMEM,I would like to wish you a Happy New Year and all the best!AMEM is an international,open access academic journal dedicated to establish an international platform for academic exchange in the field of experimental animal sciences.AMEM is jointly founded by Chinese Association for Laboratory Animal Sciences(CALAS),Asian Federation of Laboratory Animal Science Associations(AFLAS),the International Council for Laboratory Animal Science(ICLAS)and Institute of Laboratory Animal Sciences(ILAS),Chinese Academy of Medical Sciences&Peking Union Medical College.Since its first publication in 2018,it has now entered into its fourth year.展开更多
In the Chinese Year of the Dog,we are pleased to present to you the first issue of the new journal we have organized:Animal Models and Experimental Medicine(AMEM).Why do we need a new journal in this area?Laboratory a...In the Chinese Year of the Dog,we are pleased to present to you the first issue of the new journal we have organized:Animal Models and Experimental Medicine(AMEM).Why do we need a new journal in this area?Laboratory animal sciences is an emerging interdisciplinary subject,which integrates theories and methods from many disciplines,including biology,medicine,pharmacy,veterinary,bioengineering,biomedical engineering,etc.In recent years,many outstanding papers based on laboratory animals have been published around the world,highlighting how laboratory animal sciences has,among other things,provided systematic biological materials and pertinent technologies for the development of related disciplines;integration into many frontier disciplines;development of new disciplines such as comparative medicine,experimental animal medicine,and comparative biology;and supported development in fields such as life sciences,medicine,food,environment and aerospace.However,there are very few specialized journals in this field,and their impact is very limited.Therefore,it is urgent to establish a professional English-language journal to meet the need of all researchers in this important field.展开更多
The outbreak of novel coronavirus disease(COVID-19)caused by SARS-CoV-2 severely challenges the economic stability of countries around the globe.Immune responses induced by active infection and vaccination have result...The outbreak of novel coronavirus disease(COVID-19)caused by SARS-CoV-2 severely challenges the economic stability of countries around the globe.Immune responses induced by active infection and vaccination have resulted in severe complications like thrombosis and cardiac injury in a measurable number of COVID-19 cases.Hence,knowledge of dissemination of these events is of clinical importance.展开更多
Epitopes are small segmented antigenic peptides that are able to elicit the immune response by recognizing B and T-cells.In the present scenario,knowledge of immunogenic epitopes specific to severe acute respiratory s...Epitopes are small segmented antigenic peptides that are able to elicit the immune response by recognizing B and T-cells.In the present scenario,knowledge of immunogenic epitopes specific to severe acute respiratory syndrome coronavirus(SARS-CoV-2)becomes highly essential for understanding the disease pathogenesis,etiology,disease screening and also for the development of suitable viral vaccine candidates.展开更多
文摘Since its inception,Animal Models and Experimental Medicine(AMEM)has received 632 articles in total from 52 countries and regions includ-ing China,Iran,the United States,India,Nigeria,Israel,Germany,Iraq,Italy,Japan,Australia,Bangladesh,Belgium,Brazil,and Canada,among others.AMEM has become an important international exchange plat-form for innovative research achievements in the field of laboratory animal science and basic medicine.
基金Astra Zeneca R&DUniversities Federation for Animal Welfare+3 种基金Royal Society for the Prevention of Cruelty to AnimalsNovo Nordisk PharmaceuticalsGovernment of the United KingdomAAALAC International。
文摘These Chinese National Guidelines(GB/T 35892-20181)were issued February 06,2018 and became effective September 01,2018.The authors recognized the urgent need for an authentic English translation to inform the international community of the compliance requirements in China.It was appreciated that the final translation must reflect the specialist understanding of those working under the Guideline whilst remaining faithful to the meaning of the original Chinese text.A three-step translation process was therefore determined.Step 1:A professional interpretation service(KL Communications,UK)was commissioned to prepare a literal translation of the Chinese text.Supportive documents were provided which explained specialist terminology.This translation was checked by two bilingual experts.Step 2:A workshop was held in Nanjing in May 2019 to which were invited experts in laboratory animal welfare and ethical use.These included international native English-speaking and Chinese-speaking delegates.The delegates worked in multilingual teams to review sections of the literal translation ahead of the workshop,and to agree an authentic interpretation during the workshop.Step 3:Following the workshop,three bilingual experts(two native Chinese speakers and one native English speaker)reviewed the entire document to ensure consistency of terminology and general accuracy.This document is thus not a“literal translation”but an“accurate interpretation”of the original text.Any challenge of work being performed under these Guidelines should rely on the Chinese text in the first place.However,this translation may be used as mitigating evidence,especially where those performing the work are non-Chinese speakers.
基金Young Elite Scientists Sponsorship Program by CAST(YESS:2019QNRC001)National Natural Science Foundation of China Grant(31970510,81941012)+1 种基金CAMS Innovation Fund for Medical Sciences(CIFMS)grant(2021-1-I2M-034)SAFEA:Introduction of Overseas Talents in Cultural and Educational Sector(G20190001626).
文摘1|INTRODUCTION For decades,experimental animal models have been powerful tools for biomedical research and have supported most of the physiological or medical achievements recognized by Nobel Prizes,including the research that won this year's Physiology or Medicine Prize.On 4th October 2021,the Nobel Prize in Physiology or Medicine 2021 was awarded jointly to David Julius and Ardem Patapoutian"for their discoveries of receptors for temperature and touch."1 Their discoveries have profoundly changed our view of how we sense the world around us2.
文摘The 2nd Longtan Science Conference and the 40th anniversary of the Institute of Laboratory Animal Sciences,Chinese Academy of Medical Sciences&Comparative Medicine Center,Peking Union Medical College.On November 19-20,2020,the 2nd Longtan Science Conference and the 40th anniversary celebrations of the Institute of Laboratory Animal Sciences,Chinese Academy of Medical Sciences&Comparative Medicine Center,Peking Union Medical College(hereinafter referred to as"ILAS")were held in Beijing.The conference was jointly organized by the Institute and the Chinese Association for Laboratory Animal Sciences.
文摘According to the traditional Chinese zodiac,2023 is the Year of the Rabbit,which holds the meaning of life and hope due to the rabbit's vigorous reproductive ability.Over the past 5 years AMEM has flourished,initial hopes have been realized and the journal has gone from strength to strength.Following the gradual rise in submissions and the journal's increasing influence,in 2022 AMEM changed from quarterly to bimonthly,and successively launched seven themed sections-columns-includ-ing neurodegenerative disease,cardiovascular disease,and so on.
文摘At the first issue of the year 2021,I would like to extend my sincere gratitude for your continued support and attention to Animal Models and Experimental Medicine(AMEM)journal.On behalf of AMEM,I would like to wish you a Happy New Year and all the best!AMEM is an international,open access academic journal dedicated to establish an international platform for academic exchange in the field of experimental animal sciences.AMEM is jointly founded by Chinese Association for Laboratory Animal Sciences(CALAS),Asian Federation of Laboratory Animal Science Associations(AFLAS),the International Council for Laboratory Animal Science(ICLAS)and Institute of Laboratory Animal Sciences(ILAS),Chinese Academy of Medical Sciences&Peking Union Medical College.Since its first publication in 2018,it has now entered into its fourth year.
文摘In the Chinese Year of the Dog,we are pleased to present to you the first issue of the new journal we have organized:Animal Models and Experimental Medicine(AMEM).Why do we need a new journal in this area?Laboratory animal sciences is an emerging interdisciplinary subject,which integrates theories and methods from many disciplines,including biology,medicine,pharmacy,veterinary,bioengineering,biomedical engineering,etc.In recent years,many outstanding papers based on laboratory animals have been published around the world,highlighting how laboratory animal sciences has,among other things,provided systematic biological materials and pertinent technologies for the development of related disciplines;integration into many frontier disciplines;development of new disciplines such as comparative medicine,experimental animal medicine,and comparative biology;and supported development in fields such as life sciences,medicine,food,environment and aerospace.However,there are very few specialized journals in this field,and their impact is very limited.Therefore,it is urgent to establish a professional English-language journal to meet the need of all researchers in this important field.
文摘The outbreak of novel coronavirus disease(COVID-19)caused by SARS-CoV-2 severely challenges the economic stability of countries around the globe.Immune responses induced by active infection and vaccination have resulted in severe complications like thrombosis and cardiac injury in a measurable number of COVID-19 cases.Hence,knowledge of dissemination of these events is of clinical importance.
文摘Epitopes are small segmented antigenic peptides that are able to elicit the immune response by recognizing B and T-cells.In the present scenario,knowledge of immunogenic epitopes specific to severe acute respiratory syndrome coronavirus(SARS-CoV-2)becomes highly essential for understanding the disease pathogenesis,etiology,disease screening and also for the development of suitable viral vaccine candidates.
