Youth moral education is an extremely important work,which is related to the inheritance of traditional virtues of the Chinese nation,the fundamental plan of“successor,”and the construction of modern Chinese spiritu...Youth moral education is an extremely important work,which is related to the inheritance of traditional virtues of the Chinese nation,the fundamental plan of“successor,”and the construction of modern Chinese spiritual civilization.In the era of big data,the moral education of youth is facing new challenges and opportunities.The wide application of big data technology has brought about an information explosion,exposing young people to more diverse and complex social information.It not only brings opportunities for positive moral education but also many challenges.The main problems of youth moral education in the era of big data are neglected youth subjectivity,insufficient youth moral practice,and utilitarian youth value orientation.We should develop personalized moral education programs,strengthen the integration of moral knowledge and action,and pay more attention to moral practice to improve the pertinence and effectiveness of moral education for young people in the era of big data.展开更多
Retelling is a very efficient means of generative learning; it engages students in meaning reconstruction, and consequently facilitates students' reading comprehension. This study aims to explore how the retelling...Retelling is a very efficient means of generative learning; it engages students in meaning reconstruction, and consequently facilitates students' reading comprehension. This study aims to explore how the retelling technique can affect Chinese tertiary-level students' reading comprehension of narrative and expository texts.展开更多
Excited-state intramolecular proton transfer(ESIPT) molecules are broadly applied to UV absorbers, fluorescence sensing, and lighting materials. In previous work, the fluorescence colors of oxazoline-substituted hydro...Excited-state intramolecular proton transfer(ESIPT) molecules are broadly applied to UV absorbers, fluorescence sensing, and lighting materials. In previous work, the fluorescence colors of oxazoline-substituted hydroxyfluorenes and hydroxylated benzoxazole were diversified by adding the π-conjugation. There is intriguing that the mechanism of diversified fluorescence colors induced by ESIPT. Here, the density functional theory(DFT) and time-dependent DFT(TDDFT)are advised to identify the effects of π-conjugation on ESIPT and photophysical properties. The stabilized geometrical configurations, frontier molecular orbitals(FMOs) isosurfaces, and O–H stretching vibration frequency analysis demonstrate that PT processes are more active in S1state. Constructing the minimum energy pathways of ESIPT processes, we find that the calculated peak of enol and keto fluorescence of naphthoxazole(NO–OH) is distinctly bathochromic-shift relative to the oxazoline-substituted hydroxyfluorenes(Oxa–OH) configuration when adding π-conjugation-substitution, and it means that π-conjugation-substitution can diversify the fluorescence color. We hope our studies can establish new channels to devise the ESIPT-based molecules.展开更多
The attacks on in-vehicle Controller Area Network(CAN)bus messages severely disrupt normal communication between vehicles.Therefore,researches on intrusion detection models for CAN have positive business value for veh...The attacks on in-vehicle Controller Area Network(CAN)bus messages severely disrupt normal communication between vehicles.Therefore,researches on intrusion detection models for CAN have positive business value for vehicle security,and the intrusion detection technology for CAN bus messages can effectively protect the invehicle network from unlawful attacks.Previous machine learning-based models are unable to effectively identify intrusive abnormal messages due to their inherent shortcomings.Hence,to address the shortcomings of the previous machine learning-based intrusion detection technique,we propose a novel method using Attention Mechanism and AutoEncoder for Intrusion Detection(AMAEID).The AMAEID model first converts the raw hexadecimal message data into binary format to obtain better input.Then the AMAEID model encodes and decodes the binary message data using a multi-layer denoising autoencoder model to obtain a hidden feature representation that can represent the potential features behind the message data at a deeper level.Finally,the AMAEID model uses the attention mechanism and the fully connected layer network to infer whether the message is an abnormal message or not.The experimental results with three evaluation metrics on a real in-vehicle CAN bus message dataset outperform some traditional machine learning algorithms,demonstrating the effectiveness of the AMAEID model.展开更多
Objective:To explore the anti-melanogenic potential of Cyrtomium falcatum.Methods:The effects of Cyrtomium falcatum crude extract and its solvent fractions on tyrosinase activity,melanin content,and the expressions of...Objective:To explore the anti-melanogenic potential of Cyrtomium falcatum.Methods:The effects of Cyrtomium falcatum crude extract and its solvent fractions on tyrosinase activity,melanin content,and the expressions of melanogenesis-related genes and proteins were analyzed inα-melanocyte-stimulating hormone(α-MSH)-stimulated B16F10 cells.Results:α-MSH treatment significantly increased tyrosinase activity,and extracellular and intracellular melanin content,as well as the expression levels of tyrosinase,microphthalmia-associated transcription factor(MITF),tyrosinase-related protein(TRP)-1,and TRP-2 in B16F10 cells.Treatment with Cyrtomium falcatum crude extract and its solvent fractions reduced tyrosinase activity and extracellular and intracellular melanin content and downregulated the expression levels of tyrosinase,MITF,TRP-1,and TRP-2 in a dose-dependent manner.Conclusions:Cyrtomium falcatum has potential anti-melanogenesis effects and can be used as a potential source material in cosmeceutical industry for the research and development of novel lead molecules with whitening properties.展开更多
Traditional wireless sensor networks(WSNs)are typically deployed in remote and hostile environments for information collection.The wireless communication methods adopted by sensor nodes may make the network highly vul...Traditional wireless sensor networks(WSNs)are typically deployed in remote and hostile environments for information collection.The wireless communication methods adopted by sensor nodes may make the network highly vulnerable to various attacks.Traditional encryption and authentication mechanisms cannot prevent attacks launched by internal malicious nodes.The trust-based security mechanism is usually adopted to solve this problem in WSNs.However,the behavioral evidence used for trust estimation presents some uncertainties due to the open wireless medium and the inexpensive sensor nodes.Moreover,how to efficiently collect behavioral evidences are rarely discussed.To address these issues,in this paper,we present a trust management mechanism based on fuzzy logic and a cloud model.First,a type-II fuzzy logic system is used to preprocess the behavioral evidences and alleviate uncertainty.Then,the cloud model is introduced to estimate the trust values for sensor nodes.Finally,a dynamic behavior monitoring protocol is proposed to provide a balance between energy conservation and safety assurance.Simulation results demonstrate that our trust management mechanism can effectively protect the network from internal malicious attacks while enhancing the energy efficiency of behavior monitoring.展开更多
Tidal flow is a periodic movement of unsteady and non-uniform,which has acceleration and deceleration process obviously,especially in coastal shallow waters.Many researches show that vertical distribution of tidal flo...Tidal flow is a periodic movement of unsteady and non-uniform,which has acceleration and deceleration process obviously,especially in coastal shallow waters.Many researches show that vertical distribution of tidal flow Reynolds stress deviated from linear distribution.The parabolic distribution of the tidal flow Reynolds stress was proposed by Song et al.(2009).Although the model fills better with field observations and indoor experimental data,it has the lower truncated series expansion of tidal flow Reynolds stress,and the description of the distribution is not very comprehensive.By introducing the motion equation of tidal flow and improving the parabolic distribution established by Song et al.(2009),the cubic distribution of the tidal flow Reynolds stress is proposed.The cubic distribution is verified well by field data(Bowden and Fairbairn,1952;Bowden et al.,1959;Rippeth et al.,2002) and experimental data(Anwar and Atkins,1980),is consistent with the numerical model results of Kuo et al.(1996),and is compared with the parabolic distribution of the tidal flow Reynolds stress.It is shown that this cubic distribution is not only better than the parabolic distribution,but also can better reflect the basic features of Reynolds stress deviating from linear distribution downward with the tidal flow acceleration and upward with the tidal flow deceleration,for the foundation of further study on the velocity profile of tidal flow.展开更多
This study aimed to investigate the antioxidant effect of soybean milk fermented by a new type of Lactobacillus fermentum(LF-HFY02)by using D-galactose induced aging mice model.Firstly,the optimal fermentation conditi...This study aimed to investigate the antioxidant effect of soybean milk fermented by a new type of Lactobacillus fermentum(LF-HFY02)by using D-galactose induced aging mice model.Firstly,the optimal fermentation conditions was screened out by detecting the effects of different fermentation temperature and time on the active components and antioxidant activity of soybean milk in viro.And then unfermented soybean milk and the soybean milk fermented by different Lactobacillus was given by gavage to D-galactose-induced aging mouse.The activities of GSH,GSH-Px,SOD,CAT and T-AOC in serum,brain and liver of soybean milk fermented by LF-HFY02 were significantly increased,while the content of MDA and the level of AGEs in hippocampal were significantly decreased compared with D-galactose induced group.Further more,the mRNA expression of GSH and SOD in mouse liver were obviously up-regulated by soybean milk fermented by LF-HFY02.The skin tissue structure of mice in the LF-HFY02 fermented soybean milk group was more complete,the collagen fibers were increased and arranged orderly and liver inflammation has improved compared with the model group.And Western blot analysis showed that LF-HFY02 effectively upregulated EGFR,SOD and GSH protein expression in mouse liver.These findings suggest that LF-HFY02 can effectively prevent D-galactose-induced oxidation and aging in mice,and the effect was even better than that of the Lactobacillus delbruechii subsp.bulgaricus and vitamin C.Thus,LF-HFY02 may be potentially employed as a probiotic strain.In conclusion,soybean milk fermented by LF-HFY02 can increase the content of antioxidant factors and the activity of antioxidant enzymes by regulating gene and protein expression,and finally inhibit the process of tissue cell peroxidation,and improve the oxidative damage of mouse skin and liver.The results could provide a basis for the research and development and industrial production of probiotic-related fermented soybean milk products.展开更多
This research the preventive effect of Kudingcha polyphenols(Kp)on colitis based on animal experiments.Experimental mice divided into four groups,including normal group,model group,low-concentration Kp(LKP)group and h...This research the preventive effect of Kudingcha polyphenols(Kp)on colitis based on animal experiments.Experimental mice divided into four groups,including normal group,model group,low-concentration Kp(LKP)group and high-concentration Kp(HKP)group,and they all smeared and given 0.15 mL 1%oxazolone solution by lavage to induce BALB/c mice colitis.DAI,colon weight/length ratio,serum levels of cytokines,related antioxidant activities of colon tissues such,and the mRNA expressions.The experimental results show that KP can significantly(p<0.05)reduce DAI in mice with colitis and inhibit shortening of colon caused by colitis,increase colon weight/length ratio.It can also significantly reduce(p<0.05)the activities of MPO,NO,MDA in mice colon tissues with colitis,increase the activity of GSH,and significantly increase(p<0.05)the level of IL-2 and decrease the level of IL-10 in mice serum with colitis.The results of qPCR assay show that Kp can significantly increase(p<0.05)the expression of Cu/Zn-SOD,Mn-SOD,GSH-Px,CAT,c-Kit,SCF and decrease the expression of IL-8,CXCR2 in mice colon tissues with colitis.Kp has a good preventive effect on colitis,and high concentration of PT has better preventive effect.展开更多
[Objective]This study aimed to improve the yield of bacteriocins from lactic acid bacteria by optimizing the fermentation process for production of bacteriocins from lactic acid bacteria.[Method]By single-factor analy...[Objective]This study aimed to improve the yield of bacteriocins from lactic acid bacteria by optimizing the fermentation process for production of bacteriocins from lactic acid bacteria.[Method]By single-factor analysis,fermentation temperature,seed age,inoculation volume,fermentation duration and fermentation media p H were optimized to determine the best fermentation process.The inhibitory zone of bacteriocins from lactic acid bacteria was analyzed with oxford cup method,based on which the fermentation process was evaluated.[Result]The optimal fermentation process was optimized:fermentation temperature 37℃,seed age 14 h,inoculation volume 2%,fermentation duration 48 h,fermentation media p H 5.0.[Conclusion]Under the optimized fermentation conditions,the yield of bacteriocins from lactic acid bacteria was improved significantly.展开更多
A tetrahedral silver(I) cluster complex {Ag4[HC(PPh2)3](S2PPh2)3}ClO4(1,HC(PPh2)3 = 1,1,1-tris(triphenylphosphino)methane, S2PPh2 = diphenyldithiophosphinate) was synthesized by assembling silver ion with phosphor and...A tetrahedral silver(I) cluster complex {Ag4[HC(PPh2)3](S2PPh2)3}ClO4(1,HC(PPh2)3 = 1,1,1-tris(triphenylphosphino)methane, S2PPh2 = diphenyldithiophosphinate) was synthesized by assembling silver ion with phosphor and sulphur mixed-ligand system. The complex was characterized by single-crystal X-ray crystallography, high-resolution mass spectroscopy and thermal analysis. In the crystal structure, an inverted tetrahedron was constructed from Ag4 metal skeleton. The Ag4 cage was stabilized by three diphenyldithiophosphinate ligands and one 1,1,1-tris(triphenylphosphino)methane ligand. 1 exhibits luminescent properties in solid state. A bright yellow-green emission centered at 533 nm has been observed in solid state. Large Stokes' shifts with long range of emissive lifetime indicate that the emission likely originates from a triplet state parentage.展开更多
Through the calculation and analysis of the tourism economic spatial relation,it found that Liaoning central urban agglomeration tourism economic spatial relation has many problems,such as the central city is insuffic...Through the calculation and analysis of the tourism economic spatial relation,it found that Liaoning central urban agglomeration tourism economic spatial relation has many problems,such as the central city is insufficient,and the low degree of spatial relations. Therefore,this article puts forward the countermeasures,which can provide theoretical and practical reference for Liaoning central urban agglomeration tourism industry layout.展开更多
Ganoderma(lingzhi)is a famous herbal medicine and edible supplement in oriental countries for a long history.In this study,a simple micellar electrokinetic chromatography(MEKC)method was established for the analysis o...Ganoderma(lingzhi)is a famous herbal medicine and edible supplement in oriental countries for a long history.In this study,a simple micellar electrokinetic chromatography(MEKC)method was established for the analysis of nucleosides and bases,the major bioactive components in Ganoderma for the first time.By optimizing the borate concentration,the sodium dodecyl sulfate(SDS)concentration and the pH value of running buffer,10 nucleosides and bases achieved an ideal separation.In real sample analysis,the developed method was successfully used to determine the 10 target analytes in 23 batches of Ganoderma samples from different regions.Results indicated that contents of 10 investigated analytes in each sample showed obvious variation.The principal components analysis(PCA)and hierarchical cluster analysis(HCA)analysis classified the samples into three groups,and the HCA tree visualized the relationships which was mainly contributed by geographical partition.The results indicated geographical origin to be an important factor that affect the accumulation of nucleosides and bases in Ganoderma.In summary,this study provides a simple and practical strategy for quality assessment and cultivation reference of Ganoderma.展开更多
Nanoscale tetragonal BiOCl samples have been synthesized using Bi[SC12H25]3 and CHCl3 as bismuth and chlorine sources by solvothermal reactions. The structure, morphology, and formation process have been investigated ...Nanoscale tetragonal BiOCl samples have been synthesized using Bi[SC12H25]3 and CHCl3 as bismuth and chlorine sources by solvothermal reactions. The structure, morphology, and formation process have been investigated by SEM, TEM, HRTEM, XRD, and EDX analyses. The layered crystal structure feature of BiOCl may induce the growth of nano plates, which can subsequently aggregate into 3D spherical or flower-like microstructures under the presence of ethanol. The reaction temperature and the identity of secondary solvent influence the morphology. The yield of BiOCl depends on the completeness of the reaction and the degree of a competition reduction of BiOCl to Bi by ethanol. The as-synthesized 3D quasi-spherical BiOCl sample has an optical band gap of 3.15 eV, and shows much better photocatalytic performance on the degradation of methyl orange than that of commercial P25.展开更多
文摘Youth moral education is an extremely important work,which is related to the inheritance of traditional virtues of the Chinese nation,the fundamental plan of“successor,”and the construction of modern Chinese spiritual civilization.In the era of big data,the moral education of youth is facing new challenges and opportunities.The wide application of big data technology has brought about an information explosion,exposing young people to more diverse and complex social information.It not only brings opportunities for positive moral education but also many challenges.The main problems of youth moral education in the era of big data are neglected youth subjectivity,insufficient youth moral practice,and utilitarian youth value orientation.We should develop personalized moral education programs,strengthen the integration of moral knowledge and action,and pay more attention to moral practice to improve the pertinence and effectiveness of moral education for young people in the era of big data.
文摘Retelling is a very efficient means of generative learning; it engages students in meaning reconstruction, and consequently facilitates students' reading comprehension. This study aims to explore how the retelling technique can affect Chinese tertiary-level students' reading comprehension of narrative and expository texts.
基金supported by the National Natural Science Foundation of China (Grant No. 11974152)the Shenyang High level Innovative Talents Program (Grant No. RC200565)+1 种基金the Science program of Liaoning Provincial Department of Education (Grant No. LJKZ0097)the Intercollegiate cooperation project of colleges and universities of Liaoning Provincial Department of Education。
文摘Excited-state intramolecular proton transfer(ESIPT) molecules are broadly applied to UV absorbers, fluorescence sensing, and lighting materials. In previous work, the fluorescence colors of oxazoline-substituted hydroxyfluorenes and hydroxylated benzoxazole were diversified by adding the π-conjugation. There is intriguing that the mechanism of diversified fluorescence colors induced by ESIPT. Here, the density functional theory(DFT) and time-dependent DFT(TDDFT)are advised to identify the effects of π-conjugation on ESIPT and photophysical properties. The stabilized geometrical configurations, frontier molecular orbitals(FMOs) isosurfaces, and O–H stretching vibration frequency analysis demonstrate that PT processes are more active in S1state. Constructing the minimum energy pathways of ESIPT processes, we find that the calculated peak of enol and keto fluorescence of naphthoxazole(NO–OH) is distinctly bathochromic-shift relative to the oxazoline-substituted hydroxyfluorenes(Oxa–OH) configuration when adding π-conjugation-substitution, and it means that π-conjugation-substitution can diversify the fluorescence color. We hope our studies can establish new channels to devise the ESIPT-based molecules.
基金supported by Chongqing Big Data Engineering Laboratory for Children,Chongqing Electronics Engineering Technology Research Center for Interactive Learning,Project of Science and Technology Research Program of Chongqing Education Commission of China. (No.KJZD-K201801601).
文摘The attacks on in-vehicle Controller Area Network(CAN)bus messages severely disrupt normal communication between vehicles.Therefore,researches on intrusion detection models for CAN have positive business value for vehicle security,and the intrusion detection technology for CAN bus messages can effectively protect the invehicle network from unlawful attacks.Previous machine learning-based models are unable to effectively identify intrusive abnormal messages due to their inherent shortcomings.Hence,to address the shortcomings of the previous machine learning-based intrusion detection technique,we propose a novel method using Attention Mechanism and AutoEncoder for Intrusion Detection(AMAEID).The AMAEID model first converts the raw hexadecimal message data into binary format to obtain better input.Then the AMAEID model encodes and decodes the binary message data using a multi-layer denoising autoencoder model to obtain a hidden feature representation that can represent the potential features behind the message data at a deeper level.Finally,the AMAEID model uses the attention mechanism and the fully connected layer network to infer whether the message is an abnormal message or not.The experimental results with three evaluation metrics on a real in-vehicle CAN bus message dataset outperform some traditional machine learning algorithms,demonstrating the effectiveness of the AMAEID model.
基金This work was supported by the National Research Foundation of Korea(NRF)grant funded by the Korea government(MSIT)(No.2023R1A2C1006268 and RS-2023-00212560).
文摘Objective:To explore the anti-melanogenic potential of Cyrtomium falcatum.Methods:The effects of Cyrtomium falcatum crude extract and its solvent fractions on tyrosinase activity,melanin content,and the expressions of melanogenesis-related genes and proteins were analyzed inα-melanocyte-stimulating hormone(α-MSH)-stimulated B16F10 cells.Results:α-MSH treatment significantly increased tyrosinase activity,and extracellular and intracellular melanin content,as well as the expression levels of tyrosinase,microphthalmia-associated transcription factor(MITF),tyrosinase-related protein(TRP)-1,and TRP-2 in B16F10 cells.Treatment with Cyrtomium falcatum crude extract and its solvent fractions reduced tyrosinase activity and extracellular and intracellular melanin content and downregulated the expression levels of tyrosinase,MITF,TRP-1,and TRP-2 in a dose-dependent manner.Conclusions:Cyrtomium falcatum has potential anti-melanogenesis effects and can be used as a potential source material in cosmeceutical industry for the research and development of novel lead molecules with whitening properties.
基金supported in part by the Chongqing Electronics Engineering Technology Research Center for Interactive Learningin part by the Chongqing key discipline of electronic informationin part by the Science and Technology Research Program of Chongqing Municipal Education Commission(KJQN202201630)。
文摘Traditional wireless sensor networks(WSNs)are typically deployed in remote and hostile environments for information collection.The wireless communication methods adopted by sensor nodes may make the network highly vulnerable to various attacks.Traditional encryption and authentication mechanisms cannot prevent attacks launched by internal malicious nodes.The trust-based security mechanism is usually adopted to solve this problem in WSNs.However,the behavioral evidence used for trust estimation presents some uncertainties due to the open wireless medium and the inexpensive sensor nodes.Moreover,how to efficiently collect behavioral evidences are rarely discussed.To address these issues,in this paper,we present a trust management mechanism based on fuzzy logic and a cloud model.First,a type-II fuzzy logic system is used to preprocess the behavioral evidences and alleviate uncertainty.Then,the cloud model is introduced to estimate the trust values for sensor nodes.Finally,a dynamic behavior monitoring protocol is proposed to provide a balance between energy conservation and safety assurance.Simulation results demonstrate that our trust management mechanism can effectively protect the network from internal malicious attacks while enhancing the energy efficiency of behavior monitoring.
基金supported by the National Natural Science Foundation of China (Grant No. 41076008)the Science and Technology Project of Chongqing Education Committee (Grant No. KJ110409 and No. KJ111501)+1 种基金the National Engineering Research Center for Inland Waterway Regulation Program (Grant No. SLK2012A02)the National Key Technology R&D Program (Grant No. 2012BAB05B03)
文摘Tidal flow is a periodic movement of unsteady and non-uniform,which has acceleration and deceleration process obviously,especially in coastal shallow waters.Many researches show that vertical distribution of tidal flow Reynolds stress deviated from linear distribution.The parabolic distribution of the tidal flow Reynolds stress was proposed by Song et al.(2009).Although the model fills better with field observations and indoor experimental data,it has the lower truncated series expansion of tidal flow Reynolds stress,and the description of the distribution is not very comprehensive.By introducing the motion equation of tidal flow and improving the parabolic distribution established by Song et al.(2009),the cubic distribution of the tidal flow Reynolds stress is proposed.The cubic distribution is verified well by field data(Bowden and Fairbairn,1952;Bowden et al.,1959;Rippeth et al.,2002) and experimental data(Anwar and Atkins,1980),is consistent with the numerical model results of Kuo et al.(1996),and is compared with the parabolic distribution of the tidal flow Reynolds stress.It is shown that this cubic distribution is not only better than the parabolic distribution,but also can better reflect the basic features of Reynolds stress deviating from linear distribution downward with the tidal flow acceleration and upward with the tidal flow deceleration,for the foundation of further study on the velocity profile of tidal flow.
基金funded by Chongqing University Innovation Research Group Project(CXQTP20033)the Science and Technology Project of Chongqing(cstc2021jcyj-msxm X0408)Scientific and Technological Innovation Project of Construction of Double City Economic Circle in Chengdu-Chongqing Area of Chongqing Education Commission(KJCX2020052)。
文摘This study aimed to investigate the antioxidant effect of soybean milk fermented by a new type of Lactobacillus fermentum(LF-HFY02)by using D-galactose induced aging mice model.Firstly,the optimal fermentation conditions was screened out by detecting the effects of different fermentation temperature and time on the active components and antioxidant activity of soybean milk in viro.And then unfermented soybean milk and the soybean milk fermented by different Lactobacillus was given by gavage to D-galactose-induced aging mouse.The activities of GSH,GSH-Px,SOD,CAT and T-AOC in serum,brain and liver of soybean milk fermented by LF-HFY02 were significantly increased,while the content of MDA and the level of AGEs in hippocampal were significantly decreased compared with D-galactose induced group.Further more,the mRNA expression of GSH and SOD in mouse liver were obviously up-regulated by soybean milk fermented by LF-HFY02.The skin tissue structure of mice in the LF-HFY02 fermented soybean milk group was more complete,the collagen fibers were increased and arranged orderly and liver inflammation has improved compared with the model group.And Western blot analysis showed that LF-HFY02 effectively upregulated EGFR,SOD and GSH protein expression in mouse liver.These findings suggest that LF-HFY02 can effectively prevent D-galactose-induced oxidation and aging in mice,and the effect was even better than that of the Lactobacillus delbruechii subsp.bulgaricus and vitamin C.Thus,LF-HFY02 may be potentially employed as a probiotic strain.In conclusion,soybean milk fermented by LF-HFY02 can increase the content of antioxidant factors and the activity of antioxidant enzymes by regulating gene and protein expression,and finally inhibit the process of tissue cell peroxidation,and improve the oxidative damage of mouse skin and liver.The results could provide a basis for the research and development and industrial production of probiotic-related fermented soybean milk products.
基金The present research was supported by the Program for Innovation Team Building at Institutions of Higher Education in Chongqing(CXTDX201601040)the Introduction of High-level Personnel Research Start-up Fund of Chongqing University of Education(2013BSRC001),China.
文摘This research the preventive effect of Kudingcha polyphenols(Kp)on colitis based on animal experiments.Experimental mice divided into four groups,including normal group,model group,low-concentration Kp(LKP)group and high-concentration Kp(HKP)group,and they all smeared and given 0.15 mL 1%oxazolone solution by lavage to induce BALB/c mice colitis.DAI,colon weight/length ratio,serum levels of cytokines,related antioxidant activities of colon tissues such,and the mRNA expressions.The experimental results show that KP can significantly(p<0.05)reduce DAI in mice with colitis and inhibit shortening of colon caused by colitis,increase colon weight/length ratio.It can also significantly reduce(p<0.05)the activities of MPO,NO,MDA in mice colon tissues with colitis,increase the activity of GSH,and significantly increase(p<0.05)the level of IL-2 and decrease the level of IL-10 in mice serum with colitis.The results of qPCR assay show that Kp can significantly increase(p<0.05)the expression of Cu/Zn-SOD,Mn-SOD,GSH-Px,CAT,c-Kit,SCF and decrease the expression of IL-8,CXCR2 in mice colon tissues with colitis.Kp has a good preventive effect on colitis,and high concentration of PT has better preventive effect.
基金Supported by Research Project of Sichuan University of Science&Engineering(No.2011RC12,2014KY02)Scientific Research Foundation of the Education Department of Sichuan Province(No.15ZA0222)Research Project of Liquor-marking Biological Technology and Application of Key Laboratory of Sichuan Province(NJ2013-06)
文摘[Objective]This study aimed to improve the yield of bacteriocins from lactic acid bacteria by optimizing the fermentation process for production of bacteriocins from lactic acid bacteria.[Method]By single-factor analysis,fermentation temperature,seed age,inoculation volume,fermentation duration and fermentation media p H were optimized to determine the best fermentation process.The inhibitory zone of bacteriocins from lactic acid bacteria was analyzed with oxford cup method,based on which the fermentation process was evaluated.[Result]The optimal fermentation process was optimized:fermentation temperature 37℃,seed age 14 h,inoculation volume 2%,fermentation duration 48 h,fermentation media p H 5.0.[Conclusion]Under the optimized fermentation conditions,the yield of bacteriocins from lactic acid bacteria was improved significantly.
基金supported by the Science and Technology Research Program of Chongqing Municipal Education Commission(Nos.KJQN201801602,KJQN201801607)the Basic and Frontier Research Project of Chongqing Science and Technology Commission(No.cstc2018jcyjAX0110)+1 种基金the Key Laboratory for Green Chemical Technology of Chongqing University of Education(No.2016xjpt08)the Research Project of Chongqing University of Education(Nos.JG2017015,KY20180241,YX-2019-01)
文摘A tetrahedral silver(I) cluster complex {Ag4[HC(PPh2)3](S2PPh2)3}ClO4(1,HC(PPh2)3 = 1,1,1-tris(triphenylphosphino)methane, S2PPh2 = diphenyldithiophosphinate) was synthesized by assembling silver ion with phosphor and sulphur mixed-ligand system. The complex was characterized by single-crystal X-ray crystallography, high-resolution mass spectroscopy and thermal analysis. In the crystal structure, an inverted tetrahedron was constructed from Ag4 metal skeleton. The Ag4 cage was stabilized by three diphenyldithiophosphinate ligands and one 1,1,1-tris(triphenylphosphino)methane ligand. 1 exhibits luminescent properties in solid state. A bright yellow-green emission centered at 533 nm has been observed in solid state. Large Stokes' shifts with long range of emissive lifetime indicate that the emission likely originates from a triplet state parentage.
基金Supported by Science and Technology Planning Project in Anshan City in 2013
文摘Through the calculation and analysis of the tourism economic spatial relation,it found that Liaoning central urban agglomeration tourism economic spatial relation has many problems,such as the central city is insufficient,and the low degree of spatial relations. Therefore,this article puts forward the countermeasures,which can provide theoretical and practical reference for Liaoning central urban agglomeration tourism industry layout.
基金financially supported by the Research Committee of the University of Macao(MYRG2018-00239-ICMS and MYRG2014-00089-ICMS-QRCM)the Macao Science and Technology Development Fund(162/2017/A3)Guangzhou International Science and Technology Cooperation Project(File no.201807010044)。
文摘Ganoderma(lingzhi)is a famous herbal medicine and edible supplement in oriental countries for a long history.In this study,a simple micellar electrokinetic chromatography(MEKC)method was established for the analysis of nucleosides and bases,the major bioactive components in Ganoderma for the first time.By optimizing the borate concentration,the sodium dodecyl sulfate(SDS)concentration and the pH value of running buffer,10 nucleosides and bases achieved an ideal separation.In real sample analysis,the developed method was successfully used to determine the 10 target analytes in 23 batches of Ganoderma samples from different regions.Results indicated that contents of 10 investigated analytes in each sample showed obvious variation.The principal components analysis(PCA)and hierarchical cluster analysis(HCA)analysis classified the samples into three groups,and the HCA tree visualized the relationships which was mainly contributed by geographical partition.The results indicated geographical origin to be an important factor that affect the accumulation of nucleosides and bases in Ganoderma.In summary,this study provides a simple and practical strategy for quality assessment and cultivation reference of Ganoderma.
基金supported by the National Natural Science Foundation of China (20973175, 20803080)973 Program (2009CB939801, 2010CB933501)
文摘Nanoscale tetragonal BiOCl samples have been synthesized using Bi[SC12H25]3 and CHCl3 as bismuth and chlorine sources by solvothermal reactions. The structure, morphology, and formation process have been investigated by SEM, TEM, HRTEM, XRD, and EDX analyses. The layered crystal structure feature of BiOCl may induce the growth of nano plates, which can subsequently aggregate into 3D spherical or flower-like microstructures under the presence of ethanol. The reaction temperature and the identity of secondary solvent influence the morphology. The yield of BiOCl depends on the completeness of the reaction and the degree of a competition reduction of BiOCl to Bi by ethanol. The as-synthesized 3D quasi-spherical BiOCl sample has an optical band gap of 3.15 eV, and shows much better photocatalytic performance on the degradation of methyl orange than that of commercial P25.
